date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0021250
A1BG-AS1 0.0032587
A1CF -0.0002496
A2M 0.0023641
A2M-AS1 0.0040564
A2ML1 -0.0009114

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 7.72e-09 -0.1430 1.27e-05
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 5.31e-08 0.0886 4.36e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 1.24e-05 -0.2470 5.19e-03
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.26e-05 -0.1360 5.19e-03
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 3.19e-05 -0.2580 1.05e-02
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 4.99e-05 -0.2100 1.37e-02
REACTOME NONSENSE MEDIATED DECAY NMD 107 1.56e-04 -0.2120 3.42e-02
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 1.67e-04 -0.2250 3.42e-02
REACTOME COMPLEMENT CASCADE 54 2.01e-04 -0.2920 3.67e-02
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 3.59e-04 -0.1970 5.90e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 4.42e-04 -0.1200 6.59e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 7.48e-04 -0.4250 1.02e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 9.71e-04 0.0742 1.17e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 9.99e-04 0.0533 1.17e-01
REACTOME SELENOAMINO ACID METABOLISM 108 1.19e-03 -0.1800 1.21e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.25e-03 -0.1360 1.21e-01
REACTOME INFLUENZA INFECTION 149 1.26e-03 -0.1530 1.21e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 1.42e-03 -0.6510 1.29e-01
REACTOME GPCR LIGAND BINDING 444 1.71e-03 -0.0868 1.48e-01
REACTOME SUMOYLATION 179 1.80e-03 0.1350 1.48e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 2.46e-03 -0.5270 1.88e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 2.52e-03 0.2120 1.88e-01
REACTOME DEUBIQUITINATION 260 2.92e-03 0.1070 1.93e-01
REACTOME SIGNALING BY WNT 318 2.94e-03 0.0970 1.93e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 2.98e-03 0.1160 1.93e-01
REACTOME SENSORY PROCESSING OF SOUND 72 3.15e-03 -0.2010 1.93e-01
REACTOME RRNA PROCESSING 192 3.21e-03 -0.1230 1.93e-01
REACTOME PTEN REGULATION 135 3.29e-03 0.1470 1.93e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 3.59e-03 -0.1930 2.00e-01
REACTOME MUSCLE CONTRACTION 197 3.72e-03 -0.1200 2.00e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 3.78e-03 -0.7480 2.00e-01
REACTOME CARDIAC CONDUCTION 125 4.36e-03 -0.1480 2.23e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 4.60e-03 -0.3570 2.29e-01
REACTOME HATS ACETYLATE HISTONES 129 5.18e-03 0.1430 2.44e-01
REACTOME RHO GTPASE EFFECTORS 305 5.20e-03 0.0930 2.44e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 5.59e-03 -0.4280 2.55e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 6.58e-03 0.0913 2.92e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 6.96e-03 -0.0888 3.01e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 7.74e-03 0.1130 3.15e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 7.74e-03 0.1920 3.15e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 7.88e-03 -0.1330 3.15e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 8.16e-03 0.1660 3.19e-01
REACTOME CELL CYCLE CHECKPOINTS 284 8.82e-03 0.0903 3.37e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 9.03e-03 -0.2630 3.37e-01
REACTOME MEIOTIC SYNAPSIS 73 9.64e-03 0.1750 3.52e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 1.07e-02 -0.0964 3.79e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 1.08e-02 0.0554 3.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 1.12e-02 0.1610 3.83e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 1.15e-02 -0.1150 3.85e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 1.22e-02 -0.3620 3.96e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME SENSORY PERCEPTION 555 7.72e-09 -1.43e-01 1.27e-05
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 5.31e-08 8.86e-02 4.36e-05
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 1.24e-05 -2.47e-01 5.19e-03
REACTOME OLFACTORY SIGNALING PATHWAY 348 1.26e-05 -1.36e-01 5.19e-03
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 3.19e-05 -2.58e-01 1.05e-02
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 4.99e-05 -2.10e-01 1.37e-02
REACTOME NONSENSE MEDIATED DECAY NMD 107 1.56e-04 -2.12e-01 3.42e-02
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 1.67e-04 -2.25e-01 3.42e-02
REACTOME COMPLEMENT CASCADE 54 2.01e-04 -2.92e-01 3.67e-02
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 3.59e-04 -1.97e-01 5.90e-02
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 4.42e-04 -1.20e-01 6.59e-02
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 7.48e-04 -4.25e-01 1.02e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 9.71e-04 7.42e-02 1.17e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 9.99e-04 5.33e-02 1.17e-01
REACTOME SELENOAMINO ACID METABOLISM 108 1.19e-03 -1.80e-01 1.21e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.25e-03 -1.36e-01 1.21e-01
REACTOME INFLUENZA INFECTION 149 1.26e-03 -1.53e-01 1.21e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 1.42e-03 -6.51e-01 1.29e-01
REACTOME GPCR LIGAND BINDING 444 1.71e-03 -8.68e-02 1.48e-01
REACTOME SUMOYLATION 179 1.80e-03 1.35e-01 1.48e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 2.46e-03 -5.27e-01 1.88e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 2.52e-03 2.12e-01 1.88e-01
REACTOME DEUBIQUITINATION 260 2.92e-03 1.07e-01 1.93e-01
REACTOME SIGNALING BY WNT 318 2.94e-03 9.70e-02 1.93e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 2.98e-03 1.16e-01 1.93e-01
REACTOME SENSORY PROCESSING OF SOUND 72 3.15e-03 -2.01e-01 1.93e-01
REACTOME RRNA PROCESSING 192 3.21e-03 -1.23e-01 1.93e-01
REACTOME PTEN REGULATION 135 3.29e-03 1.47e-01 1.93e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 3.59e-03 -1.93e-01 2.00e-01
REACTOME MUSCLE CONTRACTION 197 3.72e-03 -1.20e-01 2.00e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 3.78e-03 -7.48e-01 2.00e-01
REACTOME CARDIAC CONDUCTION 125 4.36e-03 -1.48e-01 2.23e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 4.60e-03 -3.57e-01 2.29e-01
REACTOME HATS ACETYLATE HISTONES 129 5.18e-03 1.43e-01 2.44e-01
REACTOME RHO GTPASE EFFECTORS 305 5.20e-03 9.30e-02 2.44e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 5.59e-03 -4.28e-01 2.55e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 6.58e-03 9.13e-02 2.92e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 6.96e-03 -8.88e-02 3.01e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 7.74e-03 1.13e-01 3.15e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 7.74e-03 1.92e-01 3.15e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 7.88e-03 -1.33e-01 3.15e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 8.16e-03 1.66e-01 3.19e-01
REACTOME CELL CYCLE CHECKPOINTS 284 8.82e-03 9.03e-02 3.37e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 9.03e-03 -2.63e-01 3.37e-01
REACTOME MEIOTIC SYNAPSIS 73 9.64e-03 1.75e-01 3.52e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 1.07e-02 -9.64e-02 3.79e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 1.08e-02 5.54e-02 3.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 1.12e-02 1.61e-01 3.83e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 1.15e-02 -1.15e-01 3.85e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 1.22e-02 -3.62e-01 3.96e-01
REACTOME KERATINIZATION 210 1.26e-02 -9.99e-02 3.96e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 1.26e-02 1.88e-01 3.96e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 1.31e-02 -4.53e-01 3.96e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 1.32e-02 -2.21e-01 3.96e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 1.33e-02 2.53e-01 3.96e-01
REACTOME CELL CYCLE 666 1.40e-02 5.58e-02 4.10e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.46e-02 -6.31e-01 4.18e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 1.49e-02 3.63e-01 4.18e-01
REACTOME SIGNALING BY INTERLEUKINS 444 1.50e-02 -6.73e-02 4.18e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 1.55e-02 2.55e-01 4.23e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.59e-02 8.15e-02 4.26e-01
REACTOME EICOSANOIDS 12 1.62e-02 -4.01e-01 4.26e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 1.65e-02 -1.53e-01 4.26e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 1.66e-02 -3.99e-01 4.26e-01
REACTOME RND2 GTPASE CYCLE 42 1.69e-02 2.13e-01 4.26e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 1.75e-02 -5.19e-01 4.35e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 1.81e-02 -1.49e-01 4.44e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 1.84e-02 1.29e-01 4.45e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 1.87e-02 -1.71e-01 4.45e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 1.91e-02 -2.47e-01 4.48e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 1.94e-02 1.15e-01 4.49e-01
REACTOME CELLULAR SENESCENCE 189 2.06e-02 9.76e-02 4.70e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 2.12e-02 -5.43e-01 4.77e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 2.15e-02 -1.38e-01 4.78e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 2.23e-02 1.24e-01 4.89e-01
REACTOME CELL CYCLE MITOTIC 539 2.30e-02 5.73e-02 4.96e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 2.44e-02 -5.60e-02 5.13e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 2.47e-02 6.88e-02 5.13e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 2.52e-02 -2.70e-01 5.13e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 2.53e-02 8.58e-02 5.13e-01
REACTOME DNA REPLICATION PRE INITIATION 150 2.59e-02 1.05e-01 5.13e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 2.60e-02 -2.95e-01 5.13e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.61e-02 1.60e-01 5.13e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 2.63e-02 1.10e-01 5.13e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 2.71e-02 8.09e-02 5.23e-01
REACTOME RAB GERANYLGERANYLATION 57 2.79e-02 1.68e-01 5.23e-01
REACTOME SIGNALING BY MET 78 2.80e-02 -1.44e-01 5.23e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 2.81e-02 -1.26e-01 5.23e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 2.86e-02 4.21e-01 5.24e-01
REACTOME SIGNALING BY GPCR 673 2.90e-02 -4.94e-02 5.24e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 2.90e-02 -2.27e-01 5.24e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 3.03e-02 3.77e-01 5.41e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 3.12e-02 -2.72e-01 5.52e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 3.32e-02 -2.25e-01 5.81e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 3.40e-02 2.50e-01 5.88e-01
REACTOME M PHASE 398 3.56e-02 6.14e-02 6.04e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 3.57e-02 -1.68e-01 6.04e-01
REACTOME HDACS DEACETYLATE HISTONES 85 3.75e-02 1.30e-01 6.17e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 3.83e-02 -8.37e-02 6.17e-01
REACTOME RHO GTPASE CYCLE 423 3.83e-02 5.87e-02 6.17e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 3.85e-02 2.90e-01 6.17e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 3.85e-02 1.64e-01 6.17e-01
REACTOME BASE EXCISION REPAIR 87 3.87e-02 1.28e-01 6.17e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 3.95e-02 -1.63e-01 6.24e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 4.09e-02 1.09e-01 6.40e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 4.25e-02 -2.34e-01 6.58e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 4.37e-02 -2.67e-01 6.67e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 4.38e-02 -1.89e-01 6.67e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 4.43e-02 2.16e-01 6.67e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 4.47e-02 1.41e-01 6.67e-01
REACTOME GENE SILENCING BY RNA 133 4.63e-02 1.00e-01 6.72e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 4.66e-02 -2.87e-01 6.72e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 4.67e-02 1.44e-01 6.72e-01
REACTOME PROCESSING OF SMDT1 16 4.68e-02 2.87e-01 6.72e-01
REACTOME TCR SIGNALING 113 4.71e-02 1.08e-01 6.72e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 4.78e-02 9.52e-02 6.76e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 4.85e-02 6.82e-02 6.76e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 4.86e-02 1.09e-01 6.76e-01
REACTOME FERTILIZATION 26 4.91e-02 -2.23e-01 6.78e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 4.98e-02 1.84e-01 6.81e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 5.10e-02 3.01e-01 6.93e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 5.23e-02 -2.57e-01 7.01e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 5.27e-02 3.54e-01 7.01e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 5.29e-02 1.55e-01 7.01e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 5.43e-02 3.51e-01 7.06e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 5.49e-02 1.37e-01 7.06e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 5.51e-02 1.33e-01 7.06e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 5.57e-02 -2.36e-01 7.06e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 5.58e-02 1.99e-01 7.06e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 5.59e-02 -3.19e-01 7.06e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 5.64e-02 1.27e-01 7.06e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 5.67e-02 2.30e-01 7.06e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 5.88e-02 1.75e-01 7.20e-01
REACTOME MET PROMOTES CELL MOTILITY 41 5.96e-02 -1.70e-01 7.20e-01
REACTOME DNA REPAIR 321 5.96e-02 6.12e-02 7.20e-01
REACTOME AUTOPHAGY 144 5.96e-02 9.09e-02 7.20e-01
REACTOME ESR MEDIATED SIGNALING 210 6.03e-02 7.52e-02 7.23e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 6.20e-02 -3.11e-01 7.33e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 6.28e-02 1.48e-01 7.33e-01
REACTOME BIOLOGICAL OXIDATIONS 210 6.29e-02 -7.45e-02 7.33e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 6.29e-02 9.79e-02 7.33e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 6.37e-02 -4.37e-01 7.33e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 6.38e-02 -3.57e-01 7.33e-01
REACTOME PD 1 SIGNALING 21 6.48e-02 2.33e-01 7.33e-01
REACTOME POTASSIUM CHANNELS 102 6.50e-02 -1.06e-01 7.33e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 6.55e-02 -4.34e-01 7.33e-01
REACTOME DNA REPLICATION 178 6.56e-02 8.00e-02 7.33e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 6.71e-02 7.04e-02 7.36e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 6.76e-02 1.06e-01 7.36e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 6.79e-02 -7.38e-02 7.36e-01
REACTOME NEDDYLATION 235 6.79e-02 6.91e-02 7.36e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 6.82e-02 3.33e-01 7.36e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 6.86e-02 1.64e-01 7.36e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 6.94e-02 2.35e-01 7.40e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 7.04e-02 8.39e-02 7.46e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 7.22e-02 2.88e-01 7.60e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 7.29e-02 3.27e-01 7.63e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 7.38e-02 -2.07e-01 7.67e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 7.45e-02 -2.66e-01 7.70e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 7.60e-02 -1.08e-01 7.75e-01
REACTOME TRIGLYCERIDE METABOLISM 35 7.62e-02 -1.73e-01 7.75e-01
REACTOME CHOLINE CATABOLISM 6 7.68e-02 4.17e-01 7.75e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 7.69e-02 -8.45e-02 7.75e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 7.91e-02 1.60e-01 7.78e-01
REACTOME DIGESTION 17 7.94e-02 -2.46e-01 7.78e-01
REACTOME SLC TRANSPORTER DISORDERS 94 8.02e-02 -1.04e-01 7.78e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 8.05e-02 1.11e-01 7.78e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 8.06e-02 1.28e-01 7.78e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 8.07e-02 -9.60e-02 7.78e-01
REACTOME PYRUVATE METABOLISM 29 8.15e-02 1.87e-01 7.78e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 8.16e-02 3.56e-01 7.78e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 8.18e-02 -3.03e-01 7.78e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 8.22e-02 -4.49e-01 7.78e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 8.25e-02 1.31e-01 7.78e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 8.32e-02 -2.67e-01 7.81e-01
REACTOME ION HOMEOSTASIS 52 8.46e-02 -1.38e-01 7.86e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 8.47e-02 1.44e-01 7.86e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 8.57e-02 -4.44e-01 7.90e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 8.63e-02 -1.22e-01 7.90e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 8.73e-02 1.67e-01 7.90e-01
REACTOME ACTIVATION OF C3 AND C5 6 8.73e-02 -4.03e-01 7.90e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 8.88e-02 2.96e-01 7.90e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 8.89e-02 2.54e-01 7.90e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 8.90e-02 7.27e-02 7.90e-01
REACTOME MEIOSIS 110 8.97e-02 9.36e-02 7.90e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 8.98e-02 8.97e-02 7.90e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 9.00e-02 1.96e-01 7.90e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 9.05e-02 3.46e-01 7.91e-01
REACTOME ARMS MEDIATED ACTIVATION 7 9.19e-02 -3.68e-01 7.99e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 9.30e-02 3.23e-01 8.03e-01
REACTOME FREE FATTY ACID RECEPTORS 5 9.36e-02 4.33e-01 8.04e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 9.40e-02 1.23e-01 8.04e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 9.59e-02 1.29e-01 8.11e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 9.62e-02 2.48e-01 8.11e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 9.65e-02 3.20e-01 8.11e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 9.71e-02 1.07e-01 8.11e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 9.87e-02 -1.42e-01 8.11e-01
REACTOME G2 M CHECKPOINTS 162 9.87e-02 7.52e-02 8.11e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 9.88e-02 1.41e-01 8.11e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 9.94e-02 2.24e-01 8.11e-01
REACTOME SIGNALING BY NOTCH 234 1.01e-01 6.23e-02 8.11e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 1.01e-01 5.87e-02 8.11e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 1.01e-01 2.44e-01 8.11e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 1.02e-01 2.11e-01 8.11e-01
REACTOME PYRIMIDINE CATABOLISM 12 1.02e-01 -2.72e-01 8.11e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 1.03e-01 3.56e-01 8.11e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 1.03e-01 9.83e-02 8.11e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 1.03e-01 -9.29e-02 8.11e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 1.03e-01 2.35e-01 8.11e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 1.05e-01 1.09e-01 8.11e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 1.05e-01 -2.00e-01 8.11e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 1.05e-01 7.93e-02 8.11e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 1.05e-01 -1.91e-01 8.11e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 1.06e-01 1.39e-01 8.13e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 1.08e-01 1.67e-01 8.13e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.08e-01 1.07e-01 8.13e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 1.08e-01 3.79e-01 8.13e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 1.08e-01 3.79e-01 8.13e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 1.08e-01 1.72e-01 8.13e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 1.10e-01 9.60e-02 8.16e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 1.10e-01 3.49e-01 8.16e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 1.11e-01 2.77e-01 8.19e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 1.12e-01 1.74e-01 8.19e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 1.13e-01 -3.46e-01 8.19e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 1.13e-01 -1.95e-01 8.19e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 1.13e-01 7.98e-02 8.19e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 1.14e-01 -2.53e-01 8.19e-01
REACTOME PROTEIN FOLDING 96 1.14e-01 9.34e-02 8.19e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 1.14e-01 9.74e-02 8.19e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 1.15e-01 -2.75e-01 8.19e-01
REACTOME MISMATCH REPAIR 15 1.16e-01 2.34e-01 8.21e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 1.16e-01 -9.98e-02 8.21e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 1.17e-01 2.61e-01 8.23e-01
REACTOME RHOD GTPASE CYCLE 49 1.17e-01 1.29e-01 8.23e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 1.20e-01 9.49e-02 8.25e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 1.20e-01 4.83e-02 8.25e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 1.21e-01 7.47e-02 8.25e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 1.21e-01 -2.17e-01 8.25e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 1.21e-01 -2.98e-01 8.25e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 1.21e-01 -6.88e-02 8.25e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 1.22e-01 -2.69e-01 8.25e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 1.23e-01 2.16e-01 8.25e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 1.23e-01 -2.16e-01 8.25e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 1.23e-01 1.60e-01 8.25e-01
REACTOME MITOTIC PROPHASE 134 1.24e-01 7.70e-02 8.25e-01
REACTOME O LINKED GLYCOSYLATION 109 1.24e-01 -8.53e-02 8.25e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 1.25e-01 -2.46e-01 8.25e-01
REACTOME SNRNP ASSEMBLY 53 1.25e-01 1.22e-01 8.25e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 1.25e-01 1.42e-01 8.25e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 1.26e-01 9.19e-02 8.26e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 1.27e-01 8.82e-02 8.31e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 1.28e-01 2.65e-01 8.31e-01
REACTOME TELOMERE MAINTENANCE 106 1.29e-01 8.54e-02 8.32e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 1.30e-01 -2.69e-02 8.32e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 1.30e-01 1.65e-01 8.32e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 1.32e-01 1.78e-01 8.32e-01
REACTOME MRNA SPLICING 197 1.32e-01 6.22e-02 8.32e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 1.32e-01 -1.17e-01 8.32e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 1.33e-01 -3.34e-02 8.32e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 1.34e-01 -2.89e-01 8.32e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 1.35e-01 1.66e-01 8.32e-01
REACTOME INTERFERON SIGNALING 193 1.35e-01 6.23e-02 8.32e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 1.35e-01 -2.09e-01 8.32e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 1.36e-01 -2.87e-01 8.32e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 1.36e-01 -1.42e-01 8.32e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 1.37e-01 2.15e-01 8.32e-01
REACTOME TRNA AMINOACYLATION 40 1.38e-01 1.35e-01 8.32e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 1.39e-01 7.93e-02 8.32e-01
REACTOME MITOTIC PROMETAPHASE 194 1.39e-01 6.16e-02 8.32e-01
REACTOME MYOGENESIS 29 1.39e-01 1.59e-01 8.32e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 1.40e-01 -3.48e-01 8.32e-01
REACTOME CELLULAR RESPONSES TO STIMULI 779 1.40e-01 3.11e-02 8.32e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 1.40e-01 9.48e-02 8.32e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.41e-01 1.30e-01 8.32e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 1.41e-01 1.64e-01 8.32e-01
REACTOME DNA METHYLATION 58 1.42e-01 1.12e-01 8.32e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 1.42e-01 -2.12e-01 8.32e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 1.42e-01 3.80e-01 8.32e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 1.42e-01 9.17e-02 8.32e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 1.42e-01 2.45e-01 8.32e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 1.43e-01 1.04e-01 8.34e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 1.44e-01 1.54e-01 8.38e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 1.45e-01 1.93e-01 8.38e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 1.45e-01 2.54e-01 8.38e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 1.45e-01 -8.73e-02 8.38e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 1.46e-01 1.53e-01 8.40e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 1.47e-01 1.92e-01 8.40e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 1.48e-01 -2.52e-01 8.41e-01
REACTOME NTRK2 ACTIVATES RAC1 5 1.48e-01 -3.74e-01 8.41e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 1.52e-01 1.29e-01 8.56e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 1.52e-01 -2.07e-01 8.56e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 1.53e-01 -3.12e-01 8.56e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 1.53e-01 -1.94e-01 8.56e-01
REACTOME ECM PROTEOGLYCANS 73 1.56e-01 -9.61e-02 8.56e-01
REACTOME RET SIGNALING 40 1.57e-01 1.29e-01 8.56e-01
REACTOME SIGNAL AMPLIFICATION 33 1.57e-01 1.42e-01 8.56e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 1.58e-01 2.58e-01 8.56e-01
REACTOME HEMOSTASIS 591 1.58e-01 3.39e-02 8.56e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 1.60e-01 2.25e-01 8.56e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 1.61e-01 -2.44e-01 8.56e-01
REACTOME ELASTIC FIBRE FORMATION 44 1.61e-01 -1.22e-01 8.56e-01
REACTOME ZINC TRANSPORTERS 15 1.61e-01 -2.09e-01 8.56e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 1.62e-01 6.41e-02 8.56e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 1.64e-01 1.55e-01 8.56e-01
REACTOME CHYLOMICRON CLEARANCE 5 1.64e-01 3.59e-01 8.56e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 1.64e-01 -3.59e-01 8.56e-01
REACTOME LAMININ INTERACTIONS 28 1.64e-01 -1.52e-01 8.56e-01
REACTOME RND1 GTPASE CYCLE 41 1.65e-01 1.25e-01 8.56e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 1.65e-01 7.87e-02 8.56e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 1.65e-01 1.79e-01 8.56e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 1.66e-01 1.64e-01 8.56e-01
REACTOME TYROSINE CATABOLISM 5 1.67e-01 -3.57e-01 8.56e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 1.67e-01 -2.00e-01 8.56e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.68e-01 -8.32e-02 8.56e-01
REACTOME FRUCTOSE METABOLISM 7 1.68e-01 3.01e-01 8.56e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 1.68e-01 -3.56e-01 8.56e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 1.68e-01 -1.62e-01 8.56e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 1.69e-01 7.87e-02 8.56e-01
REACTOME GAB1 SIGNALOSOME 17 1.71e-01 1.92e-01 8.56e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 1.72e-01 -1.20e-01 8.56e-01
REACTOME L1CAM INTERACTIONS 112 1.72e-01 -7.46e-02 8.56e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 1.73e-01 -1.15e-01 8.56e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 1.73e-01 1.29e-01 8.56e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 1.73e-01 -5.80e-02 8.56e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 1.74e-01 -8.24e-02 8.56e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.75e-01 7.12e-02 8.56e-01
REACTOME FATTY ACIDS 15 1.75e-01 -2.02e-01 8.56e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 1.75e-01 7.93e-02 8.56e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 1.75e-01 4.73e-02 8.56e-01
REACTOME CA2 PATHWAY 62 1.76e-01 9.94e-02 8.56e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.77e-01 -3.02e-02 8.56e-01
REACTOME LDL CLEARANCE 19 1.77e-01 1.79e-01 8.56e-01
REACTOME CHROMOSOME MAINTENANCE 130 1.78e-01 6.84e-02 8.56e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 1.78e-01 8.50e-02 8.56e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 1.79e-01 2.59e-01 8.56e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 1.79e-01 2.34e-01 8.56e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 1.80e-01 1.88e-01 8.56e-01
REACTOME MITOCHONDRIAL TRANSLATION 93 1.81e-01 8.02e-02 8.56e-01
REACTOME CHL1 INTERACTIONS 9 1.81e-01 -2.57e-01 8.56e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 1.82e-01 1.22e-01 8.56e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 1.82e-01 -1.87e-01 8.56e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 1.82e-01 9.73e-02 8.56e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 1.84e-01 -2.56e-01 8.56e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 1.84e-01 2.22e-01 8.56e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 1.84e-01 -3.43e-01 8.56e-01
REACTOME METAL ION SLC TRANSPORTERS 23 1.84e-01 -1.60e-01 8.56e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 1.84e-01 -2.71e-01 8.56e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 1.85e-01 -1.20e-01 8.56e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 1.86e-01 9.95e-02 8.56e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 1.87e-01 2.04e-01 8.56e-01
REACTOME HCMV LATE EVENTS 110 1.87e-01 7.28e-02 8.56e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.88e-01 1.52e-01 8.56e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 1.88e-01 -1.74e-01 8.56e-01
REACTOME DIGESTION AND ABSORPTION 22 1.88e-01 -1.62e-01 8.56e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 1.88e-01 1.90e-01 8.56e-01
REACTOME NEURONAL SYSTEM 388 1.89e-01 -3.89e-02 8.56e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 1.89e-01 7.97e-02 8.56e-01
REACTOME SIGNALING BY NOTCH4 80 1.89e-01 8.50e-02 8.56e-01
REACTOME LONG TERM POTENTIATION 22 1.89e-01 -1.62e-01 8.56e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 1.90e-01 9.79e-02 8.56e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 1.90e-01 7.99e-02 8.56e-01
REACTOME CD28 CO STIMULATION 32 1.91e-01 1.34e-01 8.56e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 1.91e-01 1.51e-01 8.56e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 1.92e-01 6.41e-02 8.56e-01
REACTOME PYRIMIDINE SALVAGE 10 1.92e-01 -2.38e-01 8.56e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 1.92e-01 1.54e-01 8.56e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 1.93e-01 2.01e-01 8.56e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 1.93e-01 -1.64e-01 8.56e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 1.93e-01 1.06e-01 8.56e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 1.94e-01 -2.37e-01 8.56e-01
REACTOME UBIQUINOL BIOSYNTHESIS 8 1.94e-01 2.65e-01 8.56e-01
REACTOME PI METABOLISM 79 1.95e-01 8.44e-02 8.56e-01
REACTOME S PHASE 159 1.95e-01 5.96e-02 8.56e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 1.95e-01 -2.49e-01 8.56e-01
REACTOME XENOBIOTICS 22 1.96e-01 -1.59e-01 8.56e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 1.97e-01 2.63e-01 8.56e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 1.98e-01 -1.26e-01 8.56e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 1.98e-01 2.24e-01 8.56e-01
REACTOME DECTIN 2 FAMILY 26 1.98e-01 -1.46e-01 8.56e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 1.99e-01 1.70e-01 8.56e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 1.99e-01 1.09e-01 8.56e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 1.99e-01 -1.40e-01 8.56e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 2.03e-01 3.29e-01 8.56e-01
REACTOME SIGNALING BY VEGF 102 2.03e-01 7.29e-02 8.56e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 2.03e-01 9.06e-02 8.56e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 2.04e-01 -2.12e-01 8.56e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 2.04e-01 1.19e-01 8.56e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 2.05e-01 -2.77e-01 8.56e-01
REACTOME TRANSLATION 278 2.05e-01 -4.42e-02 8.56e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 2.05e-01 -1.73e-01 8.56e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 2.05e-01 -2.03e-01 8.56e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 2.05e-01 1.83e-01 8.56e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 2.06e-01 1.72e-01 8.56e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 2.07e-01 1.63e-01 8.56e-01
REACTOME GLUCONEOGENESIS 33 2.07e-01 -1.27e-01 8.56e-01
REACTOME RHOV GTPASE CYCLE 36 2.07e-01 1.22e-01 8.56e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 2.07e-01 7.53e-02 8.56e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 2.09e-01 -2.96e-01 8.61e-01
REACTOME PROGRAMMED CELL DEATH 204 2.09e-01 5.10e-02 8.61e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 2.10e-01 1.81e-01 8.62e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 2.11e-01 2.95e-01 8.62e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 2.11e-01 8.41e-02 8.62e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 2.14e-01 6.62e-02 8.66e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 2.14e-01 -2.54e-01 8.66e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 2.14e-01 -3.85e-02 8.66e-01
REACTOME SIGNALING BY ALK 26 2.14e-01 1.41e-01 8.66e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 2.15e-01 -2.16e-01 8.66e-01
REACTOME DOPAMINE RECEPTORS 5 2.15e-01 3.20e-01 8.66e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 2.16e-01 1.03e-01 8.66e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 2.17e-01 2.38e-01 8.69e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 2.18e-01 -2.06e-01 8.69e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 2.18e-01 1.63e-01 8.69e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 2.19e-01 -6.45e-02 8.69e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 2.22e-01 -1.31e-01 8.74e-01
REACTOME HS GAG DEGRADATION 19 2.22e-01 1.62e-01 8.74e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 2.23e-01 6.73e-02 8.74e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 2.23e-01 8.61e-02 8.74e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 2.24e-01 2.66e-01 8.74e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 2.24e-01 2.34e-01 8.74e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 2.24e-01 1.40e-01 8.74e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 2.26e-01 9.71e-02 8.74e-01
REACTOME SPERM MOTILITY AND TAXES 9 2.26e-01 2.33e-01 8.74e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 2.26e-01 2.85e-01 8.74e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 2.27e-01 7.54e-02 8.74e-01
REACTOME INTRA GOLGI TRAFFIC 43 2.28e-01 1.06e-01 8.74e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.29e-01 -1.74e-01 8.74e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 2.29e-01 1.68e-01 8.74e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 2.29e-01 6.82e-02 8.74e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 2.30e-01 -1.63e-01 8.74e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 2.30e-01 -1.02e-01 8.74e-01
REACTOME PROTEIN LOCALIZATION 153 2.30e-01 5.62e-02 8.74e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 2.32e-01 -2.08e-01 8.74e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 2.33e-01 1.84e-01 8.74e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 2.33e-01 1.54e-01 8.74e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 2.34e-01 1.12e-01 8.74e-01
REACTOME MATURATION OF PROTEIN 3A 9 2.34e-01 2.29e-01 8.74e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 2.35e-01 2.28e-01 8.74e-01
REACTOME HEME DEGRADATION 15 2.36e-01 1.77e-01 8.74e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 2.37e-01 -2.58e-01 8.74e-01
REACTOME ORGANIC CATION TRANSPORT 10 2.37e-01 2.16e-01 8.74e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 2.38e-01 3.05e-01 8.74e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 2.39e-01 5.37e-02 8.74e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 2.39e-01 2.40e-01 8.74e-01
REACTOME RAC3 GTPASE CYCLE 85 2.40e-01 7.38e-02 8.74e-01
REACTOME G0 AND EARLY G1 27 2.40e-01 1.31e-01 8.74e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 2.41e-01 -3.03e-01 8.74e-01
REACTOME COLLAGEN DEGRADATION 61 2.41e-01 -8.68e-02 8.74e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 2.43e-01 -1.87e-01 8.74e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 2.43e-01 1.44e-01 8.74e-01
REACTOME RHOF GTPASE CYCLE 40 2.43e-01 1.07e-01 8.74e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 2.43e-01 -2.38e-01 8.74e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 2.43e-01 1.11e-01 8.74e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 2.44e-01 1.17e-01 8.74e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 2.45e-01 -1.50e-01 8.74e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 2.46e-01 -2.23e-01 8.74e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 2.47e-01 -2.73e-01 8.74e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 2.47e-01 -1.54e-01 8.74e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 2.47e-01 6.84e-02 8.74e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 2.48e-01 -1.22e-01 8.74e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 2.48e-01 1.53e-01 8.74e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 2.50e-01 2.10e-01 8.74e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 2.50e-01 -1.30e-01 8.74e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 2.50e-01 1.30e-01 8.74e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 2.50e-01 7.73e-02 8.74e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 2.50e-01 1.19e-01 8.74e-01
REACTOME SARS COV 1 INFECTION 136 2.50e-01 -5.71e-02 8.74e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 2.51e-01 -2.10e-01 8.74e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 2.51e-01 2.51e-01 8.74e-01
REACTOME ENDOGENOUS STEROLS 26 2.51e-01 -1.30e-01 8.74e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 2.51e-01 -1.91e-01 8.74e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 2.52e-01 -9.77e-02 8.74e-01
REACTOME SIGNALING BY NOTCH2 32 2.52e-01 -1.17e-01 8.74e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 2.52e-01 -6.84e-02 8.74e-01
REACTOME HCMV INFECTION 152 2.53e-01 5.38e-02 8.74e-01
REACTOME RHOU GTPASE CYCLE 37 2.53e-01 1.09e-01 8.74e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 2.54e-01 2.33e-01 8.74e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 2.54e-01 1.60e-01 8.74e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 2.55e-01 -2.19e-01 8.74e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 2.55e-01 -2.19e-01 8.74e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 2.56e-01 8.41e-02 8.75e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 2.57e-01 2.67e-01 8.76e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 2.57e-01 -2.47e-01 8.76e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 2.58e-01 2.07e-01 8.76e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 2.59e-01 -2.17e-01 8.79e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 2.60e-01 5.78e-02 8.79e-01
REACTOME CARNITINE METABOLISM 13 2.61e-01 1.80e-01 8.79e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 2.61e-01 -1.13e-01 8.79e-01
REACTOME INTERFERON GAMMA SIGNALING 88 2.62e-01 6.92e-02 8.79e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 2.62e-01 6.49e-02 8.79e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 2.63e-01 1.20e-01 8.81e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 2.65e-01 -2.63e-01 8.85e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 2.65e-01 2.43e-01 8.85e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 2.66e-01 -9.93e-02 8.85e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 2.67e-01 -4.04e-02 8.86e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 2.69e-01 1.07e-01 8.89e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 2.69e-01 2.13e-01 8.89e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 2.69e-01 1.46e-01 8.89e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 2.70e-01 2.01e-01 8.90e-01
REACTOME HYDROLYSIS OF LPC 9 2.70e-01 -2.12e-01 8.90e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 2.71e-01 9.93e-02 8.91e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 2.73e-01 -2.83e-01 8.94e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 2.73e-01 2.83e-01 8.94e-01
REACTOME SYNTHESIS OF DNA 119 2.74e-01 5.80e-02 8.95e-01
REACTOME PHENYLALANINE METABOLISM 6 2.75e-01 2.58e-01 8.95e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 2.75e-01 2.23e-01 8.95e-01
REACTOME COBALAMIN CBL METABOLISM 7 2.76e-01 -2.38e-01 8.97e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 2.78e-01 2.09e-01 8.98e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 2.78e-01 7.39e-02 8.98e-01
REACTOME CIRCADIAN CLOCK 68 2.78e-01 -7.60e-02 8.98e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 2.80e-01 2.36e-01 9.02e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 2.81e-01 7.35e-02 9.02e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 2.85e-01 -1.78e-01 9.02e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 2.85e-01 6.87e-02 9.02e-01
REACTOME RECYCLING OF EIF2 GDP 7 2.85e-01 2.33e-01 9.02e-01
REACTOME PI 3K CASCADE FGFR4 19 2.86e-01 1.41e-01 9.02e-01
REACTOME HCMV EARLY EVENTS 128 2.86e-01 5.46e-02 9.02e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 2.87e-01 -1.85e-01 9.02e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 2.87e-01 2.51e-01 9.02e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 2.87e-01 -2.51e-01 9.02e-01
REACTOME METABOLISM OF STEROIDS 150 2.88e-01 5.03e-02 9.02e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 2.88e-01 1.85e-01 9.02e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.88e-01 1.02e-01 9.02e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 2.88e-01 2.32e-01 9.02e-01
REACTOME RHOT1 GTPASE CYCLE 5 2.90e-01 2.73e-01 9.02e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 2.90e-01 -1.93e-01 9.02e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 2.91e-01 -2.49e-01 9.02e-01
REACTOME SIGNALING BY SCF KIT 42 2.91e-01 9.41e-02 9.02e-01
REACTOME DIGESTION OF DIETARY LIPID 7 2.92e-01 -2.30e-01 9.02e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 2.92e-01 1.22e-01 9.02e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 2.92e-01 1.76e-01 9.02e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 2.93e-01 -1.39e-01 9.02e-01
REACTOME RAS PROCESSING 22 2.93e-01 -1.30e-01 9.02e-01
REACTOME METABOLISM OF PORPHYRINS 26 2.93e-01 1.19e-01 9.02e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 2.94e-01 -2.14e-01 9.02e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 2.95e-01 8.65e-02 9.02e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 2.95e-01 -1.32e-01 9.02e-01
REACTOME DEGRADATION OF AXIN 54 2.95e-01 8.23e-02 9.02e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 2.96e-01 -2.13e-01 9.02e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 2.97e-01 2.70e-01 9.02e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 2.97e-01 1.10e-01 9.02e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 2.98e-01 1.74e-01 9.02e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 2.98e-01 2.46e-01 9.02e-01
REACTOME CREATINE METABOLISM 9 2.99e-01 -2.00e-01 9.03e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 3.00e-01 1.04e-01 9.03e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 3.01e-01 -1.60e-01 9.03e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 3.01e-01 -1.30e-01 9.03e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 3.01e-01 1.80e-01 9.03e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 3.02e-01 -1.19e-01 9.03e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 3.03e-01 -2.25e-01 9.03e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 3.04e-01 3.46e-02 9.03e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 3.05e-01 2.42e-01 9.03e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 3.06e-01 -9.03e-02 9.03e-01
REACTOME SARS COV INFECTIONS 392 3.06e-01 3.01e-02 9.03e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 3.07e-01 7.62e-02 9.03e-01
REACTOME SIALIC ACID METABOLISM 33 3.07e-01 1.03e-01 9.03e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 3.07e-01 -2.64e-01 9.03e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 3.07e-01 6.48e-02 9.03e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 3.07e-01 1.52e-01 9.03e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 3.08e-01 -7.49e-02 9.03e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 3.08e-01 1.23e-01 9.03e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 3.10e-01 1.07e-01 9.06e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 3.11e-01 1.02e-01 9.06e-01
REACTOME MEMBRANE TRAFFICKING 603 3.11e-01 2.41e-02 9.06e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 3.12e-01 1.85e-01 9.06e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 3.12e-01 -9.48e-02 9.06e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 3.13e-01 -2.06e-01 9.06e-01
REACTOME TRNA PROCESSING 105 3.13e-01 5.70e-02 9.06e-01
REACTOME UCH PROTEINASES 99 3.14e-01 5.86e-02 9.06e-01
REACTOME INFECTIOUS DISEASE 910 3.15e-01 1.96e-02 9.06e-01
REACTOME HYALURONAN METABOLISM 17 3.15e-01 1.41e-01 9.06e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 3.15e-01 3.69e-02 9.06e-01
REACTOME SPHINGOLIPID METABOLISM 84 3.15e-01 6.34e-02 9.06e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 3.18e-01 2.18e-01 9.10e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 3.19e-01 -2.03e-01 9.12e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 3.20e-01 1.92e-01 9.12e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 3.21e-01 8.37e-02 9.12e-01
REACTOME CILIUM ASSEMBLY 190 3.22e-01 4.17e-02 9.12e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 3.22e-01 -1.91e-01 9.12e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 3.22e-01 2.56e-01 9.12e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 3.24e-01 -1.72e-01 9.12e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 3.24e-01 1.52e-01 9.12e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 3.24e-01 -4.59e-02 9.12e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 3.25e-01 -7.06e-02 9.12e-01
REACTOME PHASE 2 PLATEAU PHASE 14 3.25e-01 -1.52e-01 9.12e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 3.25e-01 -1.47e-01 9.12e-01
REACTOME EXTENSION OF TELOMERES 49 3.26e-01 8.12e-02 9.12e-01
REACTOME DNA DAMAGE REVERSAL 8 3.27e-01 2.00e-01 9.14e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 3.27e-01 2.53e-01 9.14e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 3.28e-01 1.18e-01 9.15e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 3.29e-01 -1.37e-01 9.15e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 3.30e-01 -1.08e-01 9.18e-01
REACTOME SEMAPHORIN INTERACTIONS 61 3.31e-01 -7.19e-02 9.18e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 3.32e-01 -2.12e-01 9.18e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 3.32e-01 5.88e-02 9.18e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 3.33e-01 -1.69e-01 9.18e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 3.34e-01 1.55e-01 9.19e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 3.34e-01 4.08e-02 9.19e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 3.35e-01 1.86e-01 9.19e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 3.35e-01 1.68e-01 9.19e-01
REACTOME BICARBONATE TRANSPORTERS 10 3.36e-01 -1.76e-01 9.21e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 3.38e-01 9.23e-02 9.24e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 3.40e-01 7.89e-02 9.24e-01
REACTOME G PROTEIN ACTIVATION 24 3.40e-01 1.12e-01 9.24e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 3.40e-01 -2.25e-01 9.24e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 3.41e-01 -9.73e-02 9.24e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 3.42e-01 7.69e-02 9.24e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 3.42e-01 1.26e-01 9.24e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 3.43e-01 5.88e-02 9.24e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 3.43e-01 5.88e-02 9.24e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 3.43e-01 1.07e-01 9.24e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 3.44e-01 1.33e-01 9.24e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 3.46e-01 6.52e-02 9.27e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 3.48e-01 -1.13e-01 9.28e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 3.48e-01 1.16e-01 9.28e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 3.48e-01 -8.37e-02 9.28e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 3.49e-01 1.00e-01 9.28e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 3.49e-01 -1.31e-01 9.28e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 3.50e-01 2.41e-01 9.28e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 3.50e-01 5.90e-02 9.28e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 3.51e-01 -1.20e-01 9.28e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 3.52e-01 -3.11e-02 9.28e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 3.52e-01 1.90e-01 9.28e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 3.53e-01 2.03e-01 9.28e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 3.53e-01 -9.48e-02 9.28e-01
REACTOME CS DS DEGRADATION 12 3.53e-01 1.55e-01 9.28e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 3.54e-01 -1.20e-01 9.28e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 3.55e-01 -1.03e-01 9.28e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 3.56e-01 8.05e-02 9.28e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 3.56e-01 -2.18e-01 9.28e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 3.56e-01 6.08e-02 9.28e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 3.58e-01 -1.68e-01 9.33e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 3.59e-01 -1.42e-01 9.33e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 3.60e-01 1.53e-01 9.34e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 3.63e-01 -1.41e-01 9.38e-01
REACTOME PCP CE PATHWAY 91 3.64e-01 5.51e-02 9.38e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 3.64e-01 8.63e-02 9.38e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 3.64e-01 -7.35e-02 9.38e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 3.65e-01 1.45e-01 9.38e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 3.65e-01 5.93e-02 9.38e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 3.66e-01 -1.11e-01 9.39e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 3.68e-01 5.04e-02 9.43e-01
REACTOME GLUCURONIDATION 23 3.70e-01 1.08e-01 9.45e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 3.70e-01 -6.80e-02 9.45e-01
REACTOME PARACETAMOL ADME 26 3.71e-01 -1.01e-01 9.45e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 3.71e-01 6.46e-02 9.45e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 3.73e-01 1.25e-01 9.47e-01
REACTOME GAP JUNCTION DEGRADATION 12 3.75e-01 -1.48e-01 9.47e-01
REACTOME PHOSPHOLIPID METABOLISM 201 3.75e-01 3.63e-02 9.47e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 3.75e-01 -7.91e-02 9.47e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 3.75e-01 2.29e-01 9.47e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 3.76e-01 -1.71e-01 9.47e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 3.77e-01 1.11e-01 9.48e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 3.77e-01 1.80e-01 9.48e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 3.78e-01 1.24e-01 9.48e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 3.78e-01 2.28e-01 9.48e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 3.81e-01 9.74e-02 9.48e-01
REACTOME INNATE IMMUNE SYSTEM 1002 3.81e-01 -1.63e-02 9.48e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 3.82e-01 -6.47e-02 9.48e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 3.82e-01 8.08e-02 9.48e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 3.83e-01 4.65e-02 9.48e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 3.83e-01 5.75e-02 9.48e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 3.85e-01 1.77e-01 9.48e-01
REACTOME HEME SIGNALING 47 3.85e-01 7.32e-02 9.48e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 3.85e-01 1.07e-01 9.48e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 3.86e-01 9.83e-02 9.48e-01
REACTOME CA DEPENDENT EVENTS 36 3.88e-01 -8.32e-02 9.48e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 3.88e-01 -1.33e-01 9.48e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 3.89e-01 -9.41e-02 9.48e-01
REACTOME SIGNALING BY EGFR 49 3.89e-01 7.11e-02 9.48e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 3.89e-01 1.88e-01 9.48e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 3.90e-01 -6.64e-02 9.48e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 3.90e-01 1.11e-01 9.48e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 3.91e-01 6.06e-02 9.48e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 3.91e-01 -1.17e-01 9.48e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 3.92e-01 1.05e-01 9.48e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 3.94e-01 -8.71e-02 9.48e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 3.94e-01 -3.56e-02 9.48e-01
REACTOME FASL CD95L SIGNALING 5 3.94e-01 -2.20e-01 9.48e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 3.95e-01 -7.50e-02 9.48e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 3.95e-01 7.03e-02 9.48e-01
REACTOME SIGNALING BY PTK6 54 3.95e-01 -6.69e-02 9.48e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 3.95e-01 1.64e-01 9.48e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 3.96e-01 -1.27e-01 9.48e-01
REACTOME TRAIL SIGNALING 8 3.96e-01 1.73e-01 9.48e-01
REACTOME TBC RABGAPS 40 3.96e-01 7.75e-02 9.48e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 3.96e-01 2.19e-01 9.48e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 3.96e-01 -1.85e-01 9.48e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 3.99e-01 -7.61e-02 9.52e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 4.00e-01 2.17e-01 9.52e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 4.01e-01 9.71e-02 9.52e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 4.01e-01 1.83e-01 9.52e-01
REACTOME THYROXINE BIOSYNTHESIS 10 4.02e-01 1.53e-01 9.52e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 4.04e-01 -1.11e-01 9.52e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 4.04e-01 7.93e-02 9.52e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 4.04e-01 4.29e-02 9.52e-01
REACTOME CELL CELL COMMUNICATION 126 4.05e-01 -4.30e-02 9.52e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 4.05e-01 1.52e-01 9.52e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 4.05e-01 -1.03e-01 9.52e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 4.05e-01 1.28e-01 9.52e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 4.06e-01 1.38e-01 9.53e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 4.07e-01 -8.75e-02 9.53e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 4.09e-01 -1.80e-01 9.55e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 4.11e-01 1.50e-01 9.55e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 4.11e-01 -1.09e-01 9.55e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 4.11e-01 5.53e-02 9.55e-01
REACTOME MEIOTIC RECOMBINATION 80 4.11e-01 5.32e-02 9.55e-01
REACTOME DUAL INCISION IN GG NER 39 4.11e-01 7.61e-02 9.55e-01
REACTOME TRP CHANNELS 27 4.13e-01 9.11e-02 9.55e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 4.13e-01 4.97e-02 9.55e-01
REACTOME RAC2 GTPASE CYCLE 81 4.13e-01 5.26e-02 9.55e-01
REACTOME SOS MEDIATED SIGNALLING 7 4.13e-01 -1.79e-01 9.55e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 4.15e-01 9.82e-02 9.57e-01
REACTOME LEISHMANIA INFECTION 156 4.15e-01 3.78e-02 9.57e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 4.16e-01 -6.58e-02 9.57e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 4.17e-01 4.46e-02 9.57e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 4.20e-01 -1.90e-01 9.63e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 4.21e-01 -1.24e-01 9.63e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 4.21e-01 -1.24e-01 9.63e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 4.23e-01 -2.07e-01 9.63e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 4.24e-01 5.24e-02 9.63e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 4.24e-01 2.06e-01 9.63e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 4.25e-01 -6.46e-02 9.63e-01
REACTOME SIGNALING BY HIPPO 19 4.26e-01 -1.05e-01 9.63e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 4.26e-01 1.15e-01 9.63e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 4.27e-01 -1.87e-01 9.63e-01
REACTOME FCGR ACTIVATION 11 4.28e-01 1.38e-01 9.63e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 4.29e-01 7.41e-02 9.63e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 4.31e-01 1.52e-01 9.63e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 4.31e-01 -7.92e-02 9.63e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 4.31e-01 -9.93e-02 9.63e-01
REACTOME P2Y RECEPTORS 9 4.34e-01 -1.51e-01 9.63e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 4.34e-01 8.69e-02 9.63e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 4.34e-01 1.21e-01 9.63e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 4.35e-01 1.17e-01 9.63e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 4.35e-01 1.43e-01 9.63e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 4.37e-01 -1.09e-01 9.63e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 4.37e-01 -1.20e-01 9.63e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 4.37e-01 1.35e-01 9.63e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 4.38e-01 -1.24e-01 9.63e-01
REACTOME CHYLOMICRON REMODELING 10 4.38e-01 -1.42e-01 9.63e-01
REACTOME LGI ADAM INTERACTIONS 14 4.39e-01 -1.19e-01 9.63e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 4.39e-01 -5.92e-02 9.63e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 4.40e-01 -1.19e-01 9.63e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 4.42e-01 1.19e-01 9.63e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 4.42e-01 -8.71e-02 9.63e-01
REACTOME TRYPTOPHAN CATABOLISM 14 4.43e-01 1.19e-01 9.63e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 4.44e-01 4.33e-02 9.63e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 4.44e-01 9.89e-02 9.63e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 4.44e-01 1.67e-01 9.63e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 4.45e-01 1.33e-01 9.63e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 4.45e-01 1.10e-01 9.63e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 4.46e-01 7.79e-02 9.63e-01
REACTOME ALK MUTANTS BIND TKIS 12 4.46e-01 -1.27e-01 9.63e-01
REACTOME CREB PHOSPHORYLATION 6 4.46e-01 -1.80e-01 9.63e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 4.47e-01 7.89e-02 9.63e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 4.47e-01 -1.17e-01 9.63e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 4.48e-01 -9.57e-02 9.63e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 4.48e-01 1.10e-01 9.63e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 4.48e-01 1.46e-01 9.63e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 4.48e-01 -1.03e-01 9.63e-01
REACTOME SURFACTANT METABOLISM 28 4.49e-01 -8.27e-02 9.63e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 4.49e-01 -1.17e-01 9.63e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 4.50e-01 1.65e-01 9.63e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 4.50e-01 1.45e-01 9.63e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 4.50e-01 -1.45e-01 9.63e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 4.51e-01 6.65e-02 9.63e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 4.51e-01 3.97e-02 9.63e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 4.51e-01 -6.49e-02 9.63e-01
REACTOME CGMP EFFECTS 16 4.51e-01 -1.09e-01 9.63e-01
REACTOME PROTEIN METHYLATION 17 4.52e-01 -1.05e-01 9.63e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 4.52e-01 -1.64e-01 9.63e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 4.53e-01 1.94e-01 9.64e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 4.56e-01 1.11e-01 9.65e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 4.56e-01 1.76e-01 9.65e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 4.57e-01 6.56e-02 9.65e-01
REACTOME REGULATION OF KIT SIGNALING 16 4.57e-01 1.07e-01 9.65e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 4.57e-01 -1.07e-01 9.65e-01
REACTOME AMINO ACID CONJUGATION 9 4.57e-01 -1.43e-01 9.65e-01
REACTOME MET RECEPTOR ACTIVATION 6 4.58e-01 -1.75e-01 9.65e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 4.59e-01 4.88e-02 9.65e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 4.59e-01 -1.35e-01 9.65e-01
REACTOME STABILIZATION OF P53 56 4.61e-01 5.70e-02 9.68e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 4.62e-01 -1.73e-01 9.68e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 4.62e-01 1.23e-01 9.68e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 4.63e-01 -9.25e-02 9.68e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 4.64e-01 -1.60e-01 9.68e-01
REACTOME PARASITE INFECTION 57 4.64e-01 5.60e-02 9.68e-01
REACTOME MITOPHAGY 28 4.65e-01 7.98e-02 9.68e-01
REACTOME METABOLISM OF LIPIDS 709 4.65e-01 1.61e-02 9.68e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 4.66e-01 8.26e-02 9.68e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 4.67e-01 -1.27e-01 9.68e-01
REACTOME DNA STRAND ELONGATION 31 4.67e-01 7.55e-02 9.68e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 4.69e-01 -6.54e-02 9.68e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 4.70e-01 -8.04e-02 9.68e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 4.71e-01 4.76e-02 9.68e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 4.72e-01 5.29e-02 9.68e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 4.73e-01 -8.64e-02 9.68e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 4.74e-01 -8.83e-02 9.68e-01
REACTOME DRUG ADME 103 4.75e-01 -4.07e-02 9.68e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 4.76e-01 -9.44e-02 9.68e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 4.76e-01 -1.68e-01 9.68e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 4.76e-01 -1.24e-01 9.68e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 4.77e-01 6.06e-02 9.68e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 4.78e-01 -3.94e-02 9.68e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 4.78e-01 1.18e-01 9.68e-01
REACTOME DISEASES OF METABOLISM 237 4.78e-01 -2.68e-02 9.68e-01
REACTOME IRS MEDIATED SIGNALLING 47 4.78e-01 5.98e-02 9.68e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 4.79e-01 -8.53e-02 9.68e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 4.80e-01 1.18e-01 9.68e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 4.80e-01 -1.09e-01 9.68e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 4.80e-01 7.21e-02 9.68e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 4.81e-01 8.32e-02 9.68e-01
REACTOME KERATAN SULFATE DEGRADATION 13 4.81e-01 1.13e-01 9.68e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 4.81e-01 -1.66e-01 9.68e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 4.82e-01 -1.09e-01 9.68e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 4.83e-01 -1.66e-01 9.68e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 4.84e-01 -1.28e-01 9.68e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 4.85e-01 -9.79e-02 9.68e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 4.85e-01 5.13e-02 9.68e-01
REACTOME SIGNALING BY FGFR2 72 4.85e-01 -4.76e-02 9.68e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 4.85e-01 -1.34e-01 9.68e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 4.85e-01 -7.13e-02 9.68e-01
REACTOME GABA RECEPTOR ACTIVATION 57 4.85e-01 -5.34e-02 9.68e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 4.88e-01 9.72e-02 9.69e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 4.88e-01 8.96e-02 9.69e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 4.88e-01 1.79e-01 9.69e-01
REACTOME NEUROFASCIN INTERACTIONS 6 4.88e-01 1.63e-01 9.69e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 4.89e-01 5.55e-02 9.69e-01
REACTOME LAGGING STRAND SYNTHESIS 19 4.89e-01 9.16e-02 9.69e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 4.90e-01 1.41e-01 9.69e-01
REACTOME PROTEIN UBIQUITINATION 76 4.90e-01 -4.58e-02 9.69e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 4.93e-01 5.25e-02 9.72e-01
REACTOME APOPTOSIS 173 4.94e-01 3.02e-02 9.72e-01
REACTOME HIV INFECTION 223 4.95e-01 2.65e-02 9.72e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 4.96e-01 -1.05e-01 9.72e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 4.96e-01 5.12e-02 9.72e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 4.97e-01 -1.60e-01 9.72e-01
REACTOME INFLAMMASOMES 21 4.98e-01 -8.55e-02 9.72e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 4.98e-01 5.72e-02 9.72e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 4.99e-01 1.48e-01 9.72e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 4.99e-01 1.23e-01 9.72e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 4.99e-01 1.08e-01 9.72e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 5.00e-01 8.51e-02 9.72e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 5.00e-01 1.17e-01 9.72e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 5.00e-01 -9.44e-02 9.72e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 5.01e-01 1.08e-01 9.73e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 5.04e-01 -1.16e-01 9.76e-01
REACTOME P38MAPK EVENTS 13 5.05e-01 1.07e-01 9.76e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 5.06e-01 1.11e-01 9.76e-01
REACTOME REPRODUCTION 136 5.06e-01 3.30e-02 9.76e-01
REACTOME ORGANIC ANION TRANSPORT 5 5.07e-01 -1.71e-01 9.76e-01
REACTOME METABOLISM OF STEROID HORMONES 35 5.08e-01 -6.47e-02 9.76e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 5.08e-01 -6.76e-02 9.76e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 5.08e-01 1.35e-01 9.76e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 5.08e-01 -7.80e-02 9.76e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 5.09e-01 6.45e-02 9.77e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 5.12e-01 1.26e-01 9.80e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 5.13e-01 -1.20e-01 9.80e-01
REACTOME SELECTIVE AUTOPHAGY 79 5.13e-01 4.26e-02 9.80e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 5.13e-01 4.15e-02 9.80e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 5.14e-01 -6.04e-02 9.80e-01
REACTOME SIGNALING BY NOTCH1 69 5.15e-01 4.54e-02 9.80e-01
REACTOME FANCONI ANEMIA PATHWAY 35 5.18e-01 6.32e-02 9.80e-01
REACTOME PECAM1 INTERACTIONS 12 5.18e-01 -1.08e-01 9.80e-01
REACTOME PURINE CATABOLISM 17 5.18e-01 9.05e-02 9.80e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 5.19e-01 -9.32e-02 9.80e-01
REACTOME PEXOPHAGY 11 5.20e-01 -1.12e-01 9.80e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 5.20e-01 7.02e-02 9.80e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 5.21e-01 4.21e-02 9.80e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 5.21e-01 -1.17e-01 9.80e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 5.22e-01 6.76e-02 9.80e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 5.22e-01 -3.65e-02 9.80e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 5.24e-01 1.16e-01 9.80e-01
REACTOME INSULIN PROCESSING 24 5.24e-01 -7.51e-02 9.80e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 5.27e-01 1.49e-01 9.80e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 5.27e-01 8.60e-02 9.80e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 5.27e-01 6.56e-02 9.80e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 5.28e-01 -1.49e-01 9.80e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 5.29e-01 -9.73e-02 9.80e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 5.29e-01 1.15e-01 9.80e-01
REACTOME BASIGIN INTERACTIONS 24 5.29e-01 -7.42e-02 9.80e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 5.29e-01 -8.12e-02 9.80e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 5.31e-01 -8.30e-02 9.80e-01
REACTOME CD209 DC SIGN SIGNALING 20 5.32e-01 -8.07e-02 9.80e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 5.33e-01 -1.61e-01 9.80e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 5.33e-01 -1.14e-01 9.80e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.34e-01 1.27e-01 9.80e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 5.36e-01 -3.55e-02 9.80e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 5.36e-01 4.92e-02 9.80e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 5.37e-01 5.87e-02 9.80e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 5.37e-01 1.13e-01 9.80e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 5.37e-01 3.59e-02 9.80e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 5.37e-01 6.62e-02 9.80e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 5.38e-01 1.45e-01 9.80e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 5.38e-01 -6.02e-02 9.80e-01
REACTOME PYROPTOSIS 27 5.38e-01 6.85e-02 9.80e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 5.39e-01 6.01e-02 9.80e-01
REACTOME NUCLEOTIDE SALVAGE 21 5.39e-01 -7.74e-02 9.80e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 5.39e-01 4.62e-02 9.80e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 5.39e-01 1.07e-01 9.80e-01
REACTOME NICOTINATE METABOLISM 31 5.40e-01 -6.36e-02 9.80e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 5.40e-01 -8.12e-02 9.80e-01
REACTOME G2 PHASE 5 5.40e-01 1.58e-01 9.80e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 5.41e-01 5.52e-02 9.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 5.41e-01 5.88e-02 9.80e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 5.41e-01 -5.72e-02 9.80e-01
REACTOME HEDGEHOG OFF STATE 111 5.42e-01 3.35e-02 9.80e-01
REACTOME KINESINS 59 5.43e-01 -4.58e-02 9.80e-01
REACTOME PI 3K CASCADE FGFR3 17 5.43e-01 8.52e-02 9.80e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 5.44e-01 -1.57e-01 9.80e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 5.44e-01 -5.01e-02 9.80e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 5.45e-01 -4.31e-02 9.81e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 5.45e-01 -9.34e-02 9.81e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 5.47e-01 1.10e-01 9.81e-01
REACTOME MITOTIC G2 G2 M PHASES 194 5.48e-01 2.50e-02 9.81e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 5.49e-01 4.81e-02 9.81e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 5.49e-01 4.06e-02 9.81e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 5.49e-01 -1.15e-01 9.81e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 5.50e-01 1.70e-02 9.81e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 5.50e-01 1.04e-01 9.81e-01
REACTOME SIGNALING BY ALK IN CANCER 53 5.51e-01 4.74e-02 9.81e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 5.51e-01 3.22e-02 9.81e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 5.52e-01 -7.50e-02 9.81e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 5.52e-01 -7.01e-02 9.81e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 5.58e-01 -4.99e-02 9.91e-01
REACTOME RHOQ GTPASE CYCLE 57 5.59e-01 4.47e-02 9.91e-01
REACTOME DEGRADATION OF DVL 56 5.60e-01 4.51e-02 9.91e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 5.60e-01 8.69e-02 9.91e-01
REACTOME MET RECEPTOR RECYCLING 10 5.62e-01 -1.06e-01 9.93e-01
REACTOME HDL CLEARANCE 5 5.62e-01 1.50e-01 9.93e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 5.63e-01 4.22e-02 9.93e-01
REACTOME ENOS ACTIVATION 11 5.64e-01 -1.00e-01 9.94e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 5.65e-01 -1.36e-01 9.94e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 5.65e-01 1.17e-01 9.94e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 5.66e-01 1.25e-01 9.94e-01
REACTOME METABOLISM OF POLYAMINES 56 5.67e-01 4.42e-02 9.94e-01
REACTOME DISEASES OF GLYCOSYLATION 137 5.67e-01 -2.83e-02 9.94e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 5.68e-01 5.84e-02 9.94e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 5.70e-01 8.77e-02 9.96e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 5.70e-01 -7.34e-02 9.96e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 5.72e-01 -5.97e-02 9.97e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 5.72e-01 8.43e-02 9.97e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 5.74e-01 -1.08e-01 9.98e-01
REACTOME RAP1 SIGNALLING 16 5.74e-01 -8.11e-02 9.98e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 5.75e-01 -6.49e-02 9.98e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 5.76e-01 -3.22e-02 9.98e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 5.76e-01 -3.84e-02 9.98e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 5.78e-01 -1.44e-01 9.99e-01
REACTOME SIGNALING BY CSF3 G CSF 30 5.78e-01 -5.87e-02 9.99e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 5.79e-01 -8.28e-02 9.99e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 5.80e-01 -6.39e-02 9.99e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 5.81e-01 -1.13e-01 9.99e-01
REACTOME NETRIN 1 SIGNALING 49 5.82e-01 -4.55e-02 9.99e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 5.82e-01 1.06e-01 9.99e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 5.83e-01 9.16e-02 9.99e-01
REACTOME SIGNALING BY PDGF 57 5.83e-01 -4.20e-02 9.99e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 5.84e-01 -1.05e-01 9.99e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 5.87e-01 -4.53e-02 9.99e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 5.89e-01 -1.40e-01 9.99e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 5.89e-01 4.25e-02 9.99e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 5.91e-01 6.10e-02 9.99e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 5.91e-01 -7.53e-02 9.99e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 5.92e-01 -7.74e-02 9.99e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 5.92e-01 -1.03e-01 9.99e-01
REACTOME MTOR SIGNALLING 40 5.93e-01 4.89e-02 9.99e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 5.93e-01 -1.09e-01 9.99e-01
REACTOME ADRENOCEPTORS 9 5.93e-01 -1.03e-01 9.99e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 5.94e-01 7.07e-02 9.99e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 5.95e-01 -7.92e-02 9.99e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 5.96e-01 1.08e-01 9.99e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 5.96e-01 5.18e-02 9.99e-01
REACTOME RND3 GTPASE CYCLE 41 5.97e-01 4.77e-02 9.99e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 5.98e-01 -4.35e-02 9.99e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 5.99e-01 7.84e-02 9.99e-01
REACTOME COLLAGEN FORMATION 88 5.99e-01 -3.24e-02 9.99e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 6.00e-01 -8.41e-02 9.99e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 6.01e-01 4.15e-02 9.99e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 6.02e-01 -6.15e-02 9.99e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 6.03e-01 6.71e-02 9.99e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 6.04e-01 -9.48e-02 9.99e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 6.05e-01 -9.95e-02 9.99e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 6.05e-01 -9.44e-02 9.99e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 6.06e-01 3.79e-02 9.99e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 6.07e-01 4.09e-02 9.99e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 6.07e-01 -2.98e-02 9.99e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 6.07e-01 4.65e-02 9.99e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 6.07e-01 -5.94e-02 9.99e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 6.08e-01 1.33e-01 9.99e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 6.08e-01 1.32e-01 9.99e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 6.09e-01 -1.04e-01 9.99e-01
REACTOME GLUCOSE METABOLISM 90 6.11e-01 -3.10e-02 9.99e-01
REACTOME EPHRIN SIGNALING 17 6.14e-01 -7.07e-02 9.99e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 6.14e-01 -4.67e-02 9.99e-01
REACTOME FLT3 SIGNALING 38 6.14e-01 4.73e-02 9.99e-01
REACTOME SYNTHESIS OF PI 5 6.14e-01 -1.30e-01 9.99e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 6.14e-01 -6.68e-02 9.99e-01
REACTOME HISTIDINE CATABOLISM 8 6.14e-01 -1.03e-01 9.99e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 6.15e-01 3.58e-02 9.99e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 6.15e-01 -1.18e-01 9.99e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 6.16e-01 8.73e-02 9.99e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 6.17e-01 -1.29e-01 9.99e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 6.18e-01 -8.31e-02 9.99e-01
REACTOME METABOLISM OF RNA 675 6.20e-01 1.12e-02 9.99e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 6.20e-01 -6.94e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 6.21e-01 6.56e-02 9.99e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 6.23e-01 -1.07e-01 9.99e-01
REACTOME ACTIVATION OF RAC1 12 6.23e-01 8.20e-02 9.99e-01
REACTOME ION CHANNEL TRANSPORT 172 6.23e-01 -2.17e-02 9.99e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 6.24e-01 7.07e-02 9.99e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 6.26e-01 -5.75e-02 9.99e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 6.26e-01 9.95e-02 9.99e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 6.27e-01 8.11e-02 9.99e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 6.28e-01 -1.06e-01 9.99e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 6.28e-01 -5.11e-02 9.99e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 6.29e-01 -3.64e-02 9.99e-01
REACTOME CELL JUNCTION ORGANIZATION 89 6.29e-01 -2.96e-02 9.99e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 6.29e-01 5.82e-02 9.99e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 6.29e-01 -8.82e-02 9.99e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 6.29e-01 -1.25e-01 9.99e-01
REACTOME METABOLISM OF COFACTORS 19 6.31e-01 6.37e-02 9.99e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 6.33e-01 5.51e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 6.34e-01 -8.29e-02 9.99e-01
REACTOME ALPHA DEFENSINS 6 6.34e-01 -1.12e-01 9.99e-01
REACTOME INTESTINAL ABSORPTION 5 6.35e-01 1.23e-01 9.99e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 6.35e-01 3.19e-02 9.99e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 6.36e-01 4.76e-02 9.99e-01
REACTOME SIGNALING BY ACTIVIN 15 6.38e-01 7.01e-02 9.99e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 6.39e-01 -5.91e-02 9.99e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 6.39e-01 2.39e-02 9.99e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 6.43e-01 -7.43e-02 9.99e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 6.43e-01 -9.46e-02 9.99e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 6.43e-01 -8.06e-02 9.99e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 6.44e-01 5.83e-02 9.99e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 6.44e-01 1.91e-02 9.99e-01
REACTOME MELANIN BIOSYNTHESIS 5 6.45e-01 -1.19e-01 9.99e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 6.45e-01 -6.87e-02 9.99e-01
REACTOME ERK MAPK TARGETS 20 6.46e-01 5.94e-02 9.99e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 6.47e-01 -4.35e-02 9.99e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 6.47e-01 -2.84e-02 9.99e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 6.47e-01 -1.08e-01 9.99e-01
REACTOME ACTIVATION OF SMO 18 6.48e-01 -6.22e-02 9.99e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 6.48e-01 -4.99e-02 9.99e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 6.48e-01 -5.49e-02 9.99e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 6.48e-01 1.18e-01 9.99e-01
REACTOME DSCAM INTERACTIONS 11 6.49e-01 -7.93e-02 9.99e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 6.50e-01 5.59e-02 9.99e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 6.50e-01 -2.25e-02 9.99e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 6.50e-01 -5.46e-02 9.99e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 6.51e-01 -4.49e-02 9.99e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 6.51e-01 -1.17e-01 9.99e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 6.51e-01 -5.70e-02 9.99e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 6.53e-01 5.95e-02 9.99e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 6.53e-01 -9.80e-02 9.99e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 6.54e-01 -3.50e-02 9.99e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 6.54e-01 1.92e-02 9.99e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 6.55e-01 3.94e-02 9.99e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 6.55e-01 4.31e-02 9.99e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 6.55e-01 2.71e-02 9.99e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 6.55e-01 6.45e-02 9.99e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 6.55e-01 6.26e-02 9.99e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 6.56e-01 -4.02e-02 9.99e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 6.56e-01 -5.25e-02 9.99e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 6.58e-01 -4.75e-02 9.99e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 6.59e-01 -1.14e-01 9.99e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 6.59e-01 -4.66e-02 9.99e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 6.60e-01 -2.02e-02 9.99e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 6.61e-01 5.40e-02 9.99e-01
REACTOME VLDL CLEARANCE 6 6.61e-01 -1.03e-01 9.99e-01
REACTOME THE NLRP3 INFLAMMASOME 16 6.61e-01 -6.32e-02 9.99e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 6.61e-01 -6.32e-02 9.99e-01
REACTOME SIGNALLING TO RAS 20 6.63e-01 5.63e-02 9.99e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 6.63e-01 -3.10e-02 9.99e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 6.63e-01 5.36e-02 9.99e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 6.63e-01 5.24e-02 9.99e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 6.63e-01 1.12e-01 9.99e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 6.64e-01 -4.84e-02 9.99e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 6.65e-01 1.02e-01 9.99e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 6.65e-01 7.22e-02 9.99e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 6.65e-01 7.54e-02 9.99e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 6.66e-01 -7.20e-02 9.99e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 6.66e-01 3.39e-02 9.99e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 6.67e-01 -3.27e-02 9.99e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 6.67e-01 8.79e-02 9.99e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 6.68e-01 -7.48e-02 9.99e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 6.68e-01 -7.46e-02 9.99e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 6.69e-01 5.39e-02 9.99e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 6.69e-01 -2.82e-02 9.99e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 6.69e-01 -1.01e-01 9.99e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 6.70e-01 -1.10e-01 9.99e-01
REACTOME TNF SIGNALING 54 6.71e-01 -3.34e-02 9.99e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 6.71e-01 -1.10e-01 9.99e-01
REACTOME RUNX3 REGULATES P14 ARF 10 6.72e-01 7.74e-02 9.99e-01
REACTOME COMPLEX I BIOGENESIS 49 6.72e-01 -3.50e-02 9.99e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 6.72e-01 7.73e-02 9.99e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 6.72e-01 -9.23e-02 9.99e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 6.73e-01 4.19e-02 9.99e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 6.73e-01 6.75e-02 9.99e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 6.74e-01 -9.93e-02 9.99e-01
REACTOME CIPROFLOXACIN ADME 5 6.78e-01 1.07e-01 9.99e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 6.78e-01 -6.65e-02 9.99e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 6.79e-01 -5.49e-02 9.99e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 6.79e-01 7.98e-02 9.99e-01
REACTOME DEADENYLATION OF MRNA 25 6.82e-01 -4.73e-02 9.99e-01
REACTOME SIGNALING BY FGFR1 49 6.82e-01 -3.38e-02 9.99e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 6.83e-01 -7.12e-02 9.99e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 6.83e-01 2.74e-02 9.99e-01
REACTOME RAC1 GTPASE CYCLE 172 6.84e-01 1.80e-02 9.99e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 6.84e-01 -7.83e-02 9.99e-01
REACTOME RHOC GTPASE CYCLE 71 6.84e-01 -2.79e-02 9.99e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 6.85e-01 -1.94e-02 9.99e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 6.85e-01 -5.67e-02 9.99e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 6.88e-01 3.86e-02 9.99e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 6.88e-01 5.79e-02 9.99e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 6.89e-01 1.03e-01 9.99e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 6.89e-01 -3.61e-02 9.99e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 6.90e-01 5.76e-02 9.99e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 6.90e-01 8.13e-02 9.99e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 6.91e-01 5.74e-02 9.99e-01
REACTOME VLDL ASSEMBLY 5 6.91e-01 -1.03e-01 9.99e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 6.92e-01 4.58e-02 9.99e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 6.92e-01 8.08e-02 9.99e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 6.93e-01 -3.52e-02 9.99e-01
REACTOME GLYCOLYSIS 70 6.94e-01 -2.72e-02 9.99e-01
REACTOME PTK6 EXPRESSION 5 6.94e-01 -1.02e-01 9.99e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 6.96e-01 9.21e-02 9.99e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 6.98e-01 -9.15e-02 9.99e-01
REACTOME METHYLATION 14 6.99e-01 5.97e-02 9.99e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 6.99e-01 6.45e-02 9.99e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 7.00e-01 9.94e-02 9.99e-01
REACTOME ASPIRIN ADME 42 7.01e-01 -3.42e-02 9.99e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 7.01e-01 7.83e-02 9.99e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 7.03e-01 7.35e-02 9.99e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 7.04e-01 2.46e-02 9.99e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 7.04e-01 -4.48e-02 9.99e-01
REACTOME RHOJ GTPASE CYCLE 51 7.05e-01 3.07e-02 9.99e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 7.05e-01 8.27e-02 9.99e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 7.05e-01 -5.65e-02 9.99e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 7.05e-01 4.89e-02 9.99e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 7.05e-01 -6.59e-02 9.99e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 7.05e-01 -3.69e-02 9.99e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 7.06e-01 7.26e-02 9.99e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 7.08e-01 -4.97e-02 9.99e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 7.08e-01 -4.41e-02 9.99e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 7.09e-01 -5.57e-02 9.99e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 7.09e-01 2.51e-02 9.99e-01
REACTOME METALLOTHIONEINS BIND METALS 11 7.09e-01 -6.50e-02 9.99e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 7.09e-01 8.79e-02 9.99e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 7.09e-01 -7.62e-02 9.99e-01
REACTOME NCAM1 INTERACTIONS 41 7.09e-01 -3.37e-02 9.99e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 7.10e-01 -1.95e-02 9.99e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 7.11e-01 -4.05e-02 9.99e-01
REACTOME SYNTHESIS OF PG 8 7.11e-01 7.56e-02 9.99e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 7.12e-01 3.15e-02 9.99e-01
REACTOME PI 3K CASCADE FGFR1 21 7.14e-01 4.62e-02 9.99e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 7.14e-01 -8.63e-02 9.99e-01
REACTOME ABC TRANSPORTER DISORDERS 76 7.14e-01 -2.43e-02 9.99e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 7.14e-01 6.37e-02 9.99e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 7.20e-01 2.72e-02 9.99e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 7.21e-01 -7.30e-02 9.99e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 7.21e-01 -4.13e-02 9.99e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 7.21e-01 -3.39e-02 9.99e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 7.21e-01 2.35e-02 9.99e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 7.22e-01 -4.85e-02 9.99e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 7.22e-01 3.48e-02 9.99e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 7.23e-01 3.57e-02 9.99e-01
REACTOME SYNTHESIS OF PA 38 7.23e-01 3.32e-02 9.99e-01
REACTOME PLATELET HOMEOSTASIS 85 7.24e-01 2.22e-02 9.99e-01
REACTOME SIGNALING BY NTRKS 132 7.24e-01 -1.78e-02 9.99e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 7.24e-01 9.11e-02 9.99e-01
REACTOME DARPP 32 EVENTS 24 7.24e-01 4.16e-02 9.99e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 7.24e-01 7.70e-02 9.99e-01
REACTOME RHOB GTPASE CYCLE 67 7.25e-01 2.48e-02 9.99e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 7.28e-01 4.19e-02 9.99e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 7.29e-01 1.63e-02 9.99e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 7.29e-01 -3.78e-02 9.99e-01
REACTOME LYSINE CATABOLISM 12 7.31e-01 5.74e-02 9.99e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 7.31e-01 7.95e-03 9.99e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 7.32e-01 2.86e-02 9.99e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 7.32e-01 -3.68e-02 9.99e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 7.32e-01 2.00e-02 9.99e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 7.33e-01 -6.97e-02 9.99e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 7.33e-01 8.80e-02 9.99e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 7.33e-01 -8.79e-02 9.99e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 7.34e-01 8.79e-02 9.99e-01
REACTOME COENZYME A BIOSYNTHESIS 8 7.35e-01 6.90e-02 9.99e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 7.35e-01 -2.68e-02 9.99e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 7.36e-01 5.04e-02 9.99e-01
REACTOME MIRO GTPASE CYCLE 8 7.36e-01 6.89e-02 9.99e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 7.36e-01 5.63e-02 9.99e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 7.36e-01 -2.19e-02 9.99e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 7.37e-01 2.23e-02 9.99e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 7.39e-01 3.78e-02 9.99e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 7.39e-01 8.62e-02 9.99e-01
REACTOME MRNA CAPPING 28 7.39e-01 3.63e-02 9.99e-01
REACTOME ATORVASTATIN ADME 9 7.40e-01 -6.40e-02 9.99e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 7.40e-01 5.78e-02 9.99e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 7.40e-01 2.58e-02 9.99e-01
REACTOME PHYSIOLOGICAL FACTORS 14 7.41e-01 -5.10e-02 9.99e-01
REACTOME AURKA ACTIVATION BY TPX2 69 7.42e-01 2.29e-02 9.99e-01
REACTOME REGULATED NECROSIS 57 7.43e-01 2.51e-02 9.99e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 7.44e-01 3.14e-02 9.99e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 7.45e-01 -4.43e-02 9.99e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 7.46e-01 2.89e-02 9.99e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 7.48e-01 3.79e-02 9.99e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 7.49e-01 1.77e-02 9.99e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 7.49e-01 3.12e-02 9.99e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 7.49e-01 -5.12e-02 9.99e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 7.50e-01 8.27e-03 9.99e-01
REACTOME CYP2E1 REACTIONS 10 7.50e-01 -5.82e-02 9.99e-01
REACTOME HEME BIOSYNTHESIS 13 7.50e-01 5.09e-02 9.99e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 7.51e-01 5.53e-02 9.99e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 7.52e-01 6.10e-02 9.99e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 7.52e-01 -3.99e-02 9.99e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 7.53e-01 6.06e-02 9.99e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 7.53e-01 3.37e-02 9.99e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 7.55e-01 -3.85e-02 9.99e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 7.55e-01 -5.44e-02 9.99e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 7.55e-01 -3.41e-02 9.99e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 7.55e-01 -4.99e-02 9.99e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 7.56e-01 -6.77e-02 9.99e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 7.57e-01 4.48e-02 9.99e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 7.58e-01 -4.09e-02 9.99e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 7.58e-01 5.93e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 7.58e-01 3.88e-02 9.99e-01
REACTOME ETHANOL OXIDATION 12 7.59e-01 5.12e-02 9.99e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 7.59e-01 -1.88e-02 9.99e-01
REACTOME CHYLOMICRON ASSEMBLY 10 7.59e-01 -5.59e-02 9.99e-01
REACTOME RSK ACTIVATION 5 7.60e-01 7.90e-02 9.99e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 7.61e-01 4.03e-02 9.99e-01
REACTOME DEFENSINS 33 7.61e-01 -3.06e-02 9.99e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 7.61e-01 -4.38e-02 9.99e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 7.62e-01 2.61e-02 9.99e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 7.62e-01 2.29e-02 9.99e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 7.62e-01 5.26e-02 9.99e-01
REACTOME DUAL INCISION IN TC NER 63 7.63e-01 -2.20e-02 9.99e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 7.63e-01 -2.86e-02 9.99e-01
REACTOME UREA CYCLE 9 7.64e-01 -5.79e-02 9.99e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 7.64e-01 -2.97e-02 9.99e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 7.64e-01 5.78e-02 9.99e-01
REACTOME UNWINDING OF DNA 12 7.65e-01 4.99e-02 9.99e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 7.65e-01 -6.10e-02 9.99e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 7.65e-01 -4.78e-02 9.99e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 7.65e-01 -3.15e-02 9.99e-01
REACTOME TIE2 SIGNALING 18 7.66e-01 4.06e-02 9.99e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 7.66e-01 3.85e-02 9.99e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 7.67e-01 -4.42e-02 9.99e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 7.67e-01 -4.41e-02 9.99e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 7.67e-01 -6.97e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 7.68e-01 2.92e-02 9.99e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 7.68e-01 -4.91e-02 9.99e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 7.69e-01 -4.71e-02 9.99e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 7.71e-01 -3.44e-02 9.99e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 7.71e-01 5.32e-02 9.99e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 7.71e-01 2.07e-02 9.99e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 7.71e-01 3.59e-02 9.99e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 7.71e-01 -4.20e-02 9.99e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 7.72e-01 5.92e-02 9.99e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 7.72e-01 -2.26e-02 9.99e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 7.73e-01 3.82e-02 9.99e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 7.73e-01 -7.44e-02 9.99e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 7.73e-01 -3.82e-02 9.99e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 7.74e-01 5.87e-02 9.99e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 7.74e-01 2.84e-02 9.99e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 7.74e-01 -2.93e-02 9.99e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 7.75e-01 -4.99e-02 9.99e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 7.75e-01 3.53e-02 9.99e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 7.75e-01 3.52e-02 9.99e-01
REACTOME VITAMINS 6 7.76e-01 -6.71e-02 9.99e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 7.77e-01 4.94e-02 9.99e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 7.77e-01 6.67e-02 9.99e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 7.78e-01 7.28e-02 9.99e-01
REACTOME DAP12 INTERACTIONS 37 7.79e-01 2.67e-02 9.99e-01
REACTOME REGULATION BY C FLIP 11 7.79e-01 -4.88e-02 9.99e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 7.80e-01 6.60e-02 9.99e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 7.80e-01 3.52e-02 9.99e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 7.80e-01 -2.81e-02 9.99e-01
REACTOME HEDGEHOG ON STATE 85 7.80e-01 1.75e-02 9.99e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 7.81e-01 5.36e-02 9.99e-01
REACTOME SIGNALING BY BMP 27 7.81e-01 -3.09e-02 9.99e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 7.82e-01 4.01e-02 9.99e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 7.82e-01 -6.05e-02 9.99e-01
REACTOME SARS COV 2 INFECTION 281 7.83e-01 9.57e-03 9.99e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 7.83e-01 7.12e-02 9.99e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 7.84e-01 2.20e-02 9.99e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 7.85e-01 -4.06e-02 9.99e-01
REACTOME IRS ACTIVATION 5 7.86e-01 -7.02e-02 9.99e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 7.87e-01 4.50e-02 9.99e-01
REACTOME CYTOPROTECTION BY HMOX1 59 7.88e-01 2.03e-02 9.99e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 7.89e-01 6.32e-02 9.99e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 7.89e-01 2.33e-02 9.99e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 7.89e-01 -5.15e-02 9.99e-01
REACTOME SIGNALING BY NOTCH3 48 7.90e-01 -2.22e-02 9.99e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 7.93e-01 -1.40e-02 9.99e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 7.93e-01 -2.68e-02 9.99e-01
REACTOME CRISTAE FORMATION 27 7.97e-01 2.86e-02 9.99e-01
REACTOME RHOBTB GTPASE CYCLE 34 7.97e-01 2.55e-02 9.99e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 7.98e-01 2.29e-02 9.99e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 7.98e-01 -3.82e-02 9.99e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 7.98e-01 -1.85e-02 9.99e-01
REACTOME CDC42 GTPASE CYCLE 144 7.99e-01 1.23e-02 9.99e-01
REACTOME DEATH RECEPTOR SIGNALING 143 8.00e-01 -1.23e-02 9.99e-01
REACTOME 2 LTR CIRCLE FORMATION 7 8.00e-01 -5.54e-02 9.99e-01
REACTOME STAT5 ACTIVATION 7 8.00e-01 5.53e-02 9.99e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 8.01e-01 3.25e-02 9.99e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 8.02e-01 -6.49e-02 9.99e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 8.02e-01 3.74e-02 9.99e-01
REACTOME NUCLEOTIDE CATABOLISM 35 8.02e-01 -2.45e-02 9.99e-01
REACTOME SYNTHESIS OF PC 27 8.02e-01 2.78e-02 9.99e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 8.03e-01 2.54e-02 9.99e-01
REACTOME SARS COV 2 HOST INTERACTIONS 191 8.04e-01 1.04e-02 9.99e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 8.04e-01 -6.41e-02 9.99e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 8.04e-01 -6.41e-02 9.99e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 8.05e-01 3.19e-02 9.99e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 8.05e-01 3.56e-02 9.99e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 8.05e-01 1.94e-02 9.99e-01
REACTOME DAG AND IP3 SIGNALING 40 8.06e-01 -2.24e-02 9.99e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 8.07e-01 -2.43e-02 9.99e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 8.07e-01 2.67e-02 9.99e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 8.08e-01 3.00e-02 9.99e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 8.09e-01 -5.69e-02 9.99e-01
REACTOME GPER1 SIGNALING 45 8.10e-01 -2.08e-02 9.99e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 8.10e-01 3.71e-02 9.99e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 8.11e-01 4.89e-02 9.99e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 8.11e-01 -6.17e-02 9.99e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 8.12e-01 -5.62e-02 9.99e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 8.12e-01 -1.68e-02 9.99e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 8.12e-01 1.97e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 8.13e-01 4.56e-02 9.99e-01
REACTOME PREDNISONE ADME 10 8.13e-01 4.32e-02 9.99e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 8.14e-01 -1.39e-02 9.99e-01
REACTOME ATTACHMENT AND ENTRY 16 8.14e-01 3.40e-02 9.99e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 8.14e-01 -2.26e-02 9.99e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 8.16e-01 4.75e-02 9.99e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 8.17e-01 -3.58e-02 9.99e-01
REACTOME SIGNALING BY FGFR3 39 8.17e-01 -2.15e-02 9.99e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 8.17e-01 5.45e-02 9.99e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 8.17e-01 3.15e-02 9.99e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 8.17e-01 -2.67e-02 9.99e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 8.19e-01 2.42e-02 9.99e-01
REACTOME RHOH GTPASE CYCLE 37 8.19e-01 2.17e-02 9.99e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 8.21e-01 4.62e-02 9.99e-01
REACTOME AZATHIOPRINE ADME 22 8.21e-01 2.78e-02 9.99e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 8.22e-01 -2.46e-02 9.99e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 8.22e-01 5.81e-02 9.99e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 8.22e-01 -2.60e-02 9.99e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 8.23e-01 -3.13e-02 9.99e-01
REACTOME RESPONSE TO METAL IONS 14 8.24e-01 -3.43e-02 9.99e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 8.24e-01 -3.70e-02 9.99e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 8.25e-01 -1.42e-02 9.99e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 8.26e-01 2.77e-02 9.99e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 8.27e-01 -2.83e-02 9.99e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 8.27e-01 5.15e-02 9.99e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 8.29e-01 2.50e-02 9.99e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 8.30e-01 4.38e-02 9.99e-01
REACTOME KETONE BODY METABOLISM 9 8.30e-01 4.12e-02 9.99e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 8.31e-01 -2.47e-02 9.99e-01
REACTOME SIGNALING BY ERBB2 50 8.32e-01 1.74e-02 9.99e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 8.32e-01 2.88e-02 9.99e-01
REACTOME EGFR DOWNREGULATION 30 8.33e-01 2.22e-02 9.99e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 8.35e-01 -4.02e-02 9.99e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 8.35e-01 2.19e-02 9.99e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 8.36e-01 -1.78e-02 9.99e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.36e-01 3.08e-02 9.99e-01
REACTOME REGULATION OF RAS BY GAPS 66 8.37e-01 1.46e-02 9.99e-01
REACTOME RHOG GTPASE CYCLE 71 8.38e-01 1.41e-02 9.99e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 8.38e-01 1.17e-02 9.99e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 8.38e-01 1.49e-02 9.99e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 8.39e-01 1.79e-02 9.99e-01
REACTOME MET ACTIVATES PTPN11 5 8.40e-01 5.20e-02 9.99e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 8.41e-01 2.32e-02 9.99e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 8.41e-01 2.65e-02 9.99e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 8.42e-01 2.98e-02 9.99e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 8.42e-01 4.35e-02 9.99e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 8.42e-01 -1.29e-02 9.99e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 8.42e-01 2.45e-02 9.99e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 8.42e-01 1.58e-02 9.99e-01
REACTOME FRUCTOSE CATABOLISM 5 8.44e-01 5.09e-02 9.99e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 8.44e-01 2.12e-02 9.99e-01
REACTOME FATTY ACID METABOLISM 170 8.44e-01 -8.73e-03 9.99e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 8.45e-01 -2.22e-02 9.99e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 8.45e-01 3.57e-02 9.99e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 8.45e-01 3.99e-02 9.99e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 8.45e-01 -5.04e-02 9.99e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 8.46e-01 4.25e-02 9.99e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 8.46e-01 2.44e-02 9.99e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 8.47e-01 1.39e-02 9.99e-01
REACTOME ATTENUATION PHASE 27 8.47e-01 -2.15e-02 9.99e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 8.47e-01 -1.81e-02 9.99e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 8.47e-01 4.21e-02 9.99e-01
REACTOME LIPOPHAGY 9 8.48e-01 -3.68e-02 9.99e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 8.51e-01 -2.89e-02 9.99e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 8.54e-01 -2.58e-02 9.99e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 8.55e-01 -3.74e-02 9.99e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 8.55e-01 -1.96e-02 9.99e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 8.55e-01 -9.20e-03 9.99e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 8.55e-01 1.49e-02 9.99e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 8.55e-01 -1.99e-02 9.99e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 8.56e-01 1.82e-02 9.99e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 8.56e-01 1.88e-02 9.99e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 8.56e-01 1.98e-02 9.99e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 8.57e-01 -3.68e-02 9.99e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 8.57e-01 -1.64e-02 9.99e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 8.57e-01 -3.13e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 8.58e-01 2.37e-02 9.99e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 8.60e-01 -2.28e-02 9.99e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 8.60e-01 -1.99e-02 9.99e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 8.60e-01 -2.07e-02 9.99e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 8.61e-01 2.21e-02 9.99e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 8.61e-01 2.80e-02 9.99e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 8.62e-01 2.19e-02 9.99e-01
REACTOME RELAXIN RECEPTORS 8 8.62e-01 -3.54e-02 9.99e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 8.64e-01 4.43e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 8.66e-01 -1.76e-02 9.99e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 8.66e-01 -2.81e-02 9.99e-01
REACTOME NRCAM INTERACTIONS 6 8.68e-01 -3.91e-02 9.99e-01
REACTOME INTEGRATION OF PROVIRUS 9 8.69e-01 3.17e-02 9.99e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 8.69e-01 -4.24e-02 9.99e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 8.70e-01 3.15e-02 9.99e-01
REACTOME PHOSPHORYLATION OF EMI1 6 8.70e-01 3.85e-02 9.99e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 8.71e-01 -9.50e-03 9.99e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 8.71e-01 3.83e-02 9.99e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 8.73e-01 2.12e-02 9.99e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 8.74e-01 1.49e-02 9.99e-01
REACTOME OPIOID SIGNALLING 89 8.75e-01 9.68e-03 9.99e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 8.75e-01 -3.04e-02 9.99e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 8.75e-01 1.64e-02 9.99e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 8.75e-01 -3.21e-02 9.99e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 8.76e-01 -1.68e-02 9.99e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 8.76e-01 1.00e-02 9.99e-01
REACTOME GASTRULATION 49 8.77e-01 1.28e-02 9.99e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 8.77e-01 -1.66e-02 9.99e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 8.78e-01 -3.96e-02 9.99e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 8.78e-01 -3.34e-02 9.99e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 8.78e-01 -2.66e-02 9.99e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 8.78e-01 -2.14e-02 9.99e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 8.79e-01 1.97e-02 9.99e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 8.79e-01 -3.93e-02 9.99e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 8.80e-01 3.89e-02 9.99e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 8.81e-01 2.89e-02 9.99e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 8.81e-01 -2.24e-02 9.99e-01
REACTOME LDL REMODELING 6 8.81e-01 -3.53e-02 9.99e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 8.81e-01 -1.32e-02 9.99e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 8.81e-01 1.98e-02 9.99e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 8.81e-01 -1.63e-02 9.99e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 8.81e-01 -2.22e-02 9.99e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 8.83e-01 -1.56e-02 9.99e-01
REACTOME GLYCOGEN SYNTHESIS 13 8.83e-01 -2.35e-02 9.99e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 8.83e-01 -1.94e-02 9.99e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 8.84e-01 -1.08e-02 9.99e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 8.86e-01 1.60e-02 9.99e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 8.86e-01 -3.14e-02 9.99e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 8.86e-01 1.31e-02 9.99e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 8.87e-01 1.03e-02 9.99e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 8.88e-01 2.26e-02 9.99e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 8.89e-01 8.14e-03 9.99e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 8.89e-01 1.20e-02 9.99e-01
REACTOME RECYCLING PATHWAY OF L1 43 8.90e-01 1.22e-02 9.99e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 8.90e-01 1.33e-02 9.99e-01
REACTOME SIGNALING BY FGFR4 40 8.90e-01 -1.26e-02 9.99e-01
REACTOME METALLOPROTEASE DUBS 36 8.91e-01 -1.33e-02 9.99e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 8.91e-01 -1.68e-02 9.99e-01
REACTOME SIGNALING BY FGFR 85 8.92e-01 -8.53e-03 9.99e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 8.94e-01 -1.41e-02 9.99e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 8.95e-01 -2.89e-02 9.99e-01
REACTOME PI 3K CASCADE FGFR2 22 8.96e-01 1.61e-02 9.99e-01
REACTOME MRNA EDITING 10 8.97e-01 -2.37e-02 9.99e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 8.97e-01 -1.86e-02 9.99e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 8.98e-01 -1.92e-02 9.99e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 8.98e-01 3.32e-02 9.99e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 8.98e-01 -2.22e-02 9.99e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 8.99e-01 -1.39e-02 9.99e-01
REACTOME RHOA GTPASE CYCLE 142 8.99e-01 6.15e-03 9.99e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 9.00e-01 -2.18e-02 9.99e-01
REACTOME STIMULI SENSING CHANNELS 100 9.00e-01 -7.25e-03 9.99e-01
REACTOME POLYMERASE SWITCHING 13 9.01e-01 2.00e-02 9.99e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 9.02e-01 2.51e-02 9.99e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 9.03e-01 7.72e-03 9.99e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 9.03e-01 1.71e-02 9.99e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 9.03e-01 2.12e-02 9.99e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 9.03e-01 1.70e-02 9.99e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 9.03e-01 -2.12e-02 9.99e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 9.04e-01 1.21e-02 9.99e-01
REACTOME SIGNALLING TO ERKS 34 9.04e-01 1.19e-02 9.99e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 9.05e-01 1.73e-02 9.99e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 9.06e-01 1.09e-02 9.99e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 9.07e-01 1.20e-02 9.99e-01
REACTOME HIV LIFE CYCLE 145 9.07e-01 -5.63e-03 9.99e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 9.08e-01 2.23e-02 9.99e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 9.08e-01 -2.73e-02 9.99e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 9.08e-01 -2.51e-02 9.99e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 9.09e-01 -2.35e-02 9.99e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 9.10e-01 6.00e-03 9.99e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 9.11e-01 2.64e-02 9.99e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 9.11e-01 1.03e-02 9.99e-01
REACTOME BETA DEFENSINS 27 9.11e-01 -1.24e-02 9.99e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 9.12e-01 2.87e-02 9.99e-01
REACTOME SIGNALING BY ERBB4 57 9.12e-01 -8.44e-03 9.99e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 9.12e-01 -6.19e-03 9.99e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 9.12e-01 2.12e-02 9.99e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 9.13e-01 1.07e-02 9.99e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 9.13e-01 -1.82e-02 9.99e-01
REACTOME SERINE BIOSYNTHESIS 9 9.14e-01 2.09e-02 9.99e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 9.14e-01 -1.80e-02 9.99e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 9.15e-01 -1.60e-02 9.99e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 9.15e-01 -1.77e-02 9.99e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 9.16e-01 -8.54e-03 9.99e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 9.17e-01 5.97e-03 9.99e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 9.17e-01 1.80e-02 9.99e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 9.18e-01 -2.25e-02 9.99e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 9.19e-01 2.63e-02 9.99e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 9.21e-01 -1.40e-02 1.00e+00
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 9.22e-01 1.27e-02 1.00e+00
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 9.22e-01 -1.51e-02 1.00e+00
REACTOME FORMATION OF APOPTOSOME 10 9.24e-01 1.75e-02 1.00e+00
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 9.24e-01 9.46e-03 1.00e+00
REACTOME NICOTINAMIDE SALVAGING 19 9.24e-01 -1.26e-02 1.00e+00
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 9.24e-01 2.45e-02 1.00e+00
REACTOME CALNEXIN CALRETICULIN CYCLE 26 9.24e-01 1.08e-02 1.00e+00
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 9.27e-01 5.95e-03 1.00e+00
REACTOME SYNTHESIS OF KETONE BODIES 8 9.27e-01 -1.87e-02 1.00e+00
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 9.27e-01 1.99e-02 1.00e+00
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 9.28e-01 -8.62e-03 1.00e+00
REACTOME SEROTONIN RECEPTORS 11 9.28e-01 -1.58e-02 1.00e+00
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 9.28e-01 6.04e-03 1.00e+00
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 9.31e-01 2.23e-02 1.00e+00
REACTOME DNA REPLICATION INITIATION 7 9.32e-01 1.86e-02 1.00e+00
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 9.33e-01 8.99e-03 1.00e+00
REACTOME DISEASES OF DNA REPAIR 51 9.34e-01 6.73e-03 1.00e+00
REACTOME SODIUM PROTON EXCHANGERS 7 9.34e-01 1.80e-02 1.00e+00
REACTOME SIGNALING BY WNT IN CANCER 32 9.34e-01 8.40e-03 1.00e+00
REACTOME PTK6 REGULATES CELL CYCLE 6 9.35e-01 1.93e-02 1.00e+00
REACTOME ERKS ARE INACTIVATED 13 9.35e-01 -1.30e-02 1.00e+00
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 9.37e-01 -6.24e-03 1.00e+00
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 9.37e-01 -1.62e-02 1.00e+00
REACTOME ABACAVIR ADME 9 9.37e-01 1.52e-02 1.00e+00
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 9.38e-01 8.38e-03 1.00e+00
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 9.38e-01 -1.36e-02 1.00e+00
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 9.39e-01 -8.16e-03 1.00e+00
REACTOME SIGNALING BY RETINOIC ACID 41 9.40e-01 -6.82e-03 1.00e+00
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 9.40e-01 1.54e-02 1.00e+00
REACTOME PURINE SALVAGE 12 9.41e-01 -1.24e-02 1.00e+00
REACTOME CLEC7A DECTIN 1 SIGNALING 97 9.41e-01 4.32e-03 1.00e+00
REACTOME RAF ACTIVATION 33 9.42e-01 -7.31e-03 1.00e+00
REACTOME ANCHORING FIBRIL FORMATION 13 9.42e-01 -1.16e-02 1.00e+00
REACTOME TOLL LIKE RECEPTOR CASCADES 158 9.43e-01 -3.32e-03 1.00e+00
REACTOME MAPK FAMILY SIGNALING CASCADES 314 9.44e-01 -2.32e-03 1.00e+00
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 9.44e-01 -6.23e-03 1.00e+00
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 9.45e-01 1.52e-02 1.00e+00
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 9.45e-01 1.11e-02 1.00e+00
REACTOME HDL ASSEMBLY 8 9.46e-01 1.39e-02 1.00e+00
REACTOME AMYLOID FIBER FORMATION 102 9.46e-01 3.87e-03 1.00e+00
REACTOME REGULATION OF INSULIN SECRETION 77 9.47e-01 4.37e-03 1.00e+00
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 9.49e-01 -1.40e-02 1.00e+00
REACTOME DNA DAMAGE BYPASS 47 9.49e-01 5.41e-03 1.00e+00
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 9.50e-01 -1.21e-02 1.00e+00
REACTOME GAP JUNCTION ASSEMBLY 36 9.50e-01 -5.98e-03 1.00e+00
REACTOME KILLING MECHANISMS 11 9.52e-01 -1.05e-02 1.00e+00
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 9.53e-01 -6.38e-03 1.00e+00
REACTOME SIGNALING BY ERBB2 IN CANCER 26 9.53e-01 -6.69e-03 1.00e+00
REACTOME HS GAG BIOSYNTHESIS 28 9.53e-01 6.42e-03 1.00e+00
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 9.54e-01 6.25e-03 1.00e+00
REACTOME OPSINS 7 9.54e-01 -1.27e-02 1.00e+00
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 9.54e-01 -4.96e-03 1.00e+00
REACTOME RHOBTB3 ATPASE CYCLE 8 9.56e-01 -1.12e-02 1.00e+00
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 9.57e-01 7.02e-03 1.00e+00
REACTOME SIGNALING BY NODAL 20 9.58e-01 6.74e-03 1.00e+00
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 9.59e-01 -3.42e-03 1.00e+00
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 9.59e-01 -8.00e-03 1.00e+00
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 9.59e-01 -4.97e-03 1.00e+00
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 9.59e-01 -7.20e-03 1.00e+00
REACTOME GLYCOGEN METABOLISM 22 9.59e-01 -6.29e-03 1.00e+00
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 9.59e-01 6.95e-03 1.00e+00
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 9.60e-01 -1.10e-02 1.00e+00
REACTOME SMOOTH MUSCLE CONTRACTION 43 9.61e-01 4.34e-03 1.00e+00
REACTOME REGULATION OF IFNG SIGNALING 14 9.61e-01 -7.52e-03 1.00e+00
REACTOME METABOLISM OF CARBOHYDRATES 279 9.63e-01 1.60e-03 1.00e+00
REACTOME SIGNAL ATTENUATION 10 9.64e-01 -8.34e-03 1.00e+00
REACTOME ESTROGEN BIOSYNTHESIS 6 9.64e-01 -1.07e-02 1.00e+00
REACTOME NEUTROPHIL DEGRANULATION 460 9.65e-01 1.20e-03 1.00e+00
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 9.65e-01 -4.72e-03 1.00e+00
REACTOME PROTEIN REPAIR 6 9.66e-01 1.01e-02 1.00e+00
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 9.67e-01 4.66e-03 1.00e+00
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 9.67e-01 -5.83e-03 1.00e+00
REACTOME HSF1 ACTIVATION 29 9.67e-01 4.46e-03 1.00e+00
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 9.67e-01 -4.96e-03 1.00e+00
REACTOME EPH EPHRIN SIGNALING 90 9.68e-01 2.45e-03 1.00e+00
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 9.68e-01 -2.43e-03 1.00e+00
REACTOME INTERLEUKIN 18 SIGNALING 8 9.70e-01 -7.64e-03 1.00e+00
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 9.70e-01 5.95e-03 1.00e+00
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 9.70e-01 -2.58e-03 1.00e+00
REACTOME HDL REMODELING 10 9.71e-01 -6.65e-03 1.00e+00
REACTOME INTEGRIN SIGNALING 27 9.71e-01 -3.99e-03 1.00e+00
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 9.72e-01 -2.83e-03 1.00e+00
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 9.72e-01 5.18e-03 1.00e+00
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 9.73e-01 -3.40e-03 1.00e+00
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 9.73e-01 -4.67e-03 1.00e+00
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 9.74e-01 -2.57e-03 1.00e+00
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 9.75e-01 -2.32e-03 1.00e+00
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 9.76e-01 -6.68e-03 1.00e+00
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 9.76e-01 4.04e-03 1.00e+00
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 9.77e-01 6.94e-03 1.00e+00
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 9.78e-01 4.68e-03 1.00e+00
REACTOME PROPIONYL COA CATABOLISM 5 9.78e-01 -7.05e-03 1.00e+00
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 9.79e-01 2.16e-03 1.00e+00
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 9.79e-01 2.69e-03 1.00e+00
REACTOME DAP12 SIGNALING 27 9.79e-01 -2.87e-03 1.00e+00
REACTOME GLUTATHIONE CONJUGATION 33 9.80e-01 2.52e-03 1.00e+00
REACTOME SIGNALING BY MST1 5 9.80e-01 -6.47e-03 1.00e+00
REACTOME MTORC1 MEDIATED SIGNALLING 23 9.80e-01 2.99e-03 1.00e+00
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 9.81e-01 1.26e-03 1.00e+00
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 9.81e-01 2.55e-03 1.00e+00
REACTOME SYNTHESIS OF PE 13 9.82e-01 -3.64e-03 1.00e+00
REACTOME AGGREPHAGY 42 9.84e-01 -1.83e-03 1.00e+00
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 9.84e-01 4.79e-03 1.00e+00
REACTOME SYNDECAN INTERACTIONS 26 9.84e-01 2.25e-03 1.00e+00
REACTOME RIBAVIRIN ADME 11 9.84e-01 3.45e-03 1.00e+00
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 9.84e-01 3.57e-03 1.00e+00
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 9.86e-01 1.73e-03 1.00e+00
REACTOME FORMATION OF AXIAL MESODERM 14 9.86e-01 -2.70e-03 1.00e+00
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 9.87e-01 3.39e-03 1.00e+00
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 9.87e-01 4.18e-03 1.00e+00
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 9.88e-01 2.44e-03 1.00e+00
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 9.89e-01 -1.48e-03 1.00e+00
REACTOME SIGNALING BY HEDGEHOG 148 9.91e-01 -5.60e-04 1.00e+00
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 9.91e-01 2.82e-03 1.00e+00
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 9.92e-01 2.44e-03 1.00e+00
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 9.93e-01 6.74e-04 1.00e+00
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 9.93e-01 8.91e-04 1.00e+00
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 9.93e-01 -1.01e-03 1.00e+00
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 9.94e-01 -1.02e-03 1.00e+00
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 9.95e-01 -9.70e-04 1.00e+00
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 9.95e-01 -6.45e-04 1.00e+00
REACTOME PI3K AKT ACTIVATION 9 9.95e-01 1.20e-03 1.00e+00
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 9.95e-01 -1.10e-03 1.00e+00
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 9.96e-01 4.55e-04 1.00e+00
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 9.96e-01 3.74e-04 1.00e+00
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 9.97e-01 -7.27e-04 1.00e+00
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 9.98e-01 -5.64e-04 1.00e+00
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 9.99e-01 4.09e-04 1.00e+00
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 9.99e-01 2.55e-04 1.00e+00
REACTOME SIGNALING BY LEPTIN 11 1.00e+00 -9.92e-05 1.00e+00
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 1.00e+00 3.44e-06 1.00e+00


Detailed Gene set reports



REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 7.72e-09
s.dist -0.143
p.adjustANOVA 1.27e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR56B4 -12153
OR51B6 -12101
OR4D11 -12082
OR52E2 -12073
OR10Z1 -12069
OR2AG1 -12068
OR52E6 -12056
OR8B4 -12048
OR10J3 -12045
OR56A1 -12010
OR2L5 -11976
RLBP1 -11935
OR51F1 -11924
TAS2R39 -11899
OR5C1 -11896
OR5T3 -11885
OR51G2 -11734
OR2S2 -11728
OR51S1 -11725
OR51T1 -11684

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR56B4 -12153.0
OR51B6 -12101.0
OR4D11 -12082.0
OR52E2 -12073.0
OR10Z1 -12069.0
OR2AG1 -12068.0
OR52E6 -12056.0
OR8B4 -12048.0
OR10J3 -12045.0
OR56A1 -12010.0
OR2L5 -11976.0
RLBP1 -11935.0
OR51F1 -11924.0
TAS2R39 -11899.0
OR5C1 -11896.0
OR5T3 -11885.0
OR51G2 -11734.0
OR2S2 -11728.0
OR51S1 -11725.0
OR51T1 -11684.0
OR10G4 -11675.0
TAS1R3 -11649.0
OR4N2 -11647.0
OR2AT4 -11641.0
OR8G5 -11611.0
OR56B1 -11604.0
OR10P1 -11596.0
OR13D1 -11563.0
OR2H1 -11558.0
OR10X1 -11533.0
OR8D2 -11499.0
OR10G2 -11496.0
OR5B3 -11489.0
OR10H2 -11482.0
OR5P3 -11457.0
OR51B4 -11435.0
OR51F2 -11431.0
OR6N2 -11422.0
OR4D6 -11405.0
OR5A1 -11395.0
OR2M7 -11394.0
OR5A2 -11370.0
OR5T2 -11367.0
OR6Y1 -11359.0
OR51B2 -11341.0
OR5P2 -11336.0
OR8H3 -11326.0
OR10J1 -11319.0
OR52R1 -11307.0
RDH5 -11293.0
OR2C3 -11289.0
OR2J2 -11273.0
OR2V1 -11265.0
RBP3 -11260.0
OR52A5 -11153.0
SLC17A8 -11148.0
OR7D4 -11110.0
OR51G1 -11104.0
AKR1C1 -11103.0
OR51V1 -11092.0
OR6C74 -11090.0
OR6B1 -11088.0
OR52B2 -11077.0
OR10V1 -11060.0
OR11H4 -11043.0
USH1C -11018.0
OR6B3 -11005.0
RTP2 -10992.0
STRC -10961.0
OR5AK2 -10931.0
TAS2R4 -10892.0
SCNN1D -10885.0
OR6C4 -10853.0
TAS2R43 -10850.0
OR2T12 -10835.0
TAS2R13 -10820.0
OR6C65 -10792.0
OR8B2 -10779.0
OR10H5 -10772.0
CALHM3 -10767.0
PDE6A -10757.0
OR5T1 -10736.0
OR9G4 -10693.0
OR8K5 -10681.0
APOA4 -10673.0
OR51E1 -10653.0
OR2Y1 -10589.0
GRK1 -10548.0
OR51Q1 -10539.0
HSD17B6 -10488.0
APOC3 -10450.0
OR6X1 -10423.0
RDH16 -10367.0
RHO -10342.0
ACTB -10333.0
OR10J5 -10327.0
OR9A2 -10309.0
OR52I1 -10292.0
RBP2 -10234.0
OR2AG2 -10212.0
OR6C6 -10206.0
OR5K4 -10163.0
EPS8L2 -10129.0
OR5D14 -10125.0
OR2T33 -10116.0
EPB41L1 -10094.0
CLPS -10023.0
GNAT1 -10008.0
OR5W2 -9953.0
OR2D3 -9942.0
OR6K2 -9934.0
OR10A4 -9881.0
LRRC52 -9867.0
SCN3A -9865.0
OR13C2 -9774.0
OR51B5 -9744.0
OR51D1 -9653.0
ANO2 -9650.0
TAS2R40 -9648.0
CACNA2D2 -9629.0
OR5M10 -9620.0
OR2D2 -9610.0
RGS9BP -9573.0
OR1E2 -9571.0
OR4C46 -9534.0
OR6K3 -9527.0
BSN -9492.0
OR10C1 -9435.0
OR8I2 -9434.0
OR8U1 -9389.0
OR8G1 -9367.0
RAB3A -9326.0
APOM -9284.0
OR10H3 -9243.0
BCO1 -9216.0
OR52W1 -9162.0
SCN2A -9149.0
STRA6 -9068.0
OR2B2 -9057.0
OR52K1 -8976.0
FNTA -8962.0
OR4X1 -8958.0
OR6B2 -8921.0
RDH8 -8885.0
OR5AS1 -8884.0
OR5B12 -8861.0
TMC2 -8826.0
CLIC5 -8805.0
OR10K2 -8784.0
TAS2R41 -8779.0
HSPG2 -8775.0
FSCN2 -8771.0
OR12D3 -8757.0
PNLIP -8732.0
GPIHBP1 -8711.0
OR5AN1 -8695.0
CALHM1 -8694.0
CHRNA9 -8675.0
OR9G1 -8668.5
OR9G9 -8668.5
OR6C70 -8602.0
OR52D1 -8593.0
STX1A -8545.0
OR1A1 -8493.0
ABCA4 -8482.0
OTOG -8474.0
EPB41L3 -8462.0
SDC1 -8387.0
CACNA1D -8381.0
OR10A6 -8325.0
OR7C2 -8305.0
OR5M3 -8269.0
CNGB1 -8214.0
TAS2R8 -8192.0
OR2A14 -8172.0
LRP2 -8171.0
OR6N1 -8142.0
OR5L2 -8110.0
OR6A2 -8106.0
OR5AU1 -8089.0
ACTG1 -8054.0
GRM4 -7974.0
OR10Q1 -7954.0
OR1Q1 -7890.0
OR5B21 -7883.0
KCNMA1 -7872.0
OTOF -7829.0
TRPM5 -7821.0
TAS1R1 -7788.0
CTBP2 -7781.0
OR10AG1 -7745.0
TAS2R16 -7742.0
OR2G3 -7728.0
OR2M3 -7726.0
OR6V1 -7706.0
TAS2R38 -7698.0
OR2AP1 -7675.0
OR2M5 -7601.0
SAG -7570.0
OR52N1 -7555.0
OR1F1 -7519.0
OR4M1 -7498.0
OR5B17 -7496.0
CDH23 -7423.0
RPE65 -7316.0
SCN2B -7285.0
TAS2R3 -7236.0
TMIE -7197.0
SLC24A1 -7174.0
OR7A5 -7141.0
XIRP2 -7108.0
OR1N1 -7027.0
CAPZA2 -6878.0
RBP1 -6824.0
GPC6 -6777.0
OR1J2 -6762.0
OR51M1 -6758.0
LRP1 -6745.0
OR4C3 -6652.0
OR51L1 -6642.0
OR1G1 -6635.0
OR2A12 -6632.0
OR1J1 -6614.0
GNG13 -6611.0
OR5J2 -6564.0
OR7A17 -6489.0
OR9A4 -6417.0
OR8A1 -6401.0
LPL -6239.0
OR1M1 -6235.0
OR52L1 -6201.0
OR52H1 -6158.0
OR8U8 -6155.0
GPC5 -6153.0
OR14J1 -6142.0
KCNN2 -6029.0
EBF1 -6009.0
CNGA4 -5981.0
OR4C45 -5927.0
OR2A5 -5882.0
RDH10 -5830.0
TAS1R2 -5814.0
KCNJ2 -5795.0
OR9K2 -5763.0
APOA1 -5666.0
APOC2 -5655.0
OR2H2 -5600.0
LRP12 -5516.0
ESPNL -5465.0
OR2C1 -5461.0
METAP2 -5432.0
OR6C3 -5390.0
GUCA1C -5382.0
EPS8 -5326.0
RDH12 -5251.0
OR2T4 -5221.0
OR10G7 -5135.0
KCNQ4 -5051.0
OR2Z1 -4973.0
OR2B3 -4963.0
OR2AE1 -4827.0
OR11A1 -4761.0
OR1I1 -4739.0
RCVRN -4616.0
RDX -4606.0
ATP2B1 -4576.0
OR10S1 -4483.0
GNB1 -4430.0
OR8D1 -4357.0
TRIOBP -4299.0
OR5AR1 -4218.0
ATP2B2 -4206.0
USH1G -4174.0
GUCA1A -4093.0
CAMKMT -4076.0
OR56A4 -4072.0
CAPZA1 -3984.0
OR7A10 -3914.0
GRM1 -3850.0
OR2B6 -3841.0
OR2AK2 -3791.0
OR10A5 -3758.0
OR5M1 -3700.0
NMT1 -3670.0
OR9Q2 -3651.0
GNAL -3644.0
OR4F6 -3594.0
LHX2 -3582.0
LDLR -3415.0
OR6T1 -3276.0
OR4D9 -3273.0
MYH9 -3268.0
SPTAN1 -3189.0
OR2F2 -3154.0
PLB1 -3149.0
OR1C1 -3028.0
RTP1 -2943.0
OR51I2 -2925.0
OR10K1 -2863.0
REEP1 -2739.0
OR11L1 -2714.0
OR4A5 -2675.0
SDR9C7 -2619.0
SCN1B -2616.0
MYO3A -2539.0
OR10A2 -2468.0
OR2T1 -2429.0
TAS2R5 -2330.0
GPC2 -2281.0
PJVK -2268.0
SCN9A -2207.0
MYO3B -2181.0
OR7G3 -2161.0
SCN4B -2060.0
GRXCR1 -1984.0
OR8D4 -1969.0
PCLO -1899.0
CNGA1 -1885.0
OR1N2 -1825.0
OTOGL -1817.0
OR5B2 -1747.0
TWF2 -1680.0
OR6Q1 -1587.0
PLS1 -1346.0
OR2T8 -1279.0
CALM1 -1278.0
OR2L13 -1249.0
GRXCR2 -1244.0
LRP10 -1230.0
CABP1 -1228.0
PCDH15 -1159.0
MYO7A -1144.0
OR1S1 -1107.0
OR2W1 -1092.0
OR8H1 -1013.0
OR56A5 -986.0
RBP4 -954.0
MYO15A -883.0
RETSAT -736.0
OR10H1 -692.0
OR52M1 -578.0
OR1B1 -561.0
GSN -546.0
MYO1C -537.0
OR13C3 -484.0
NMT2 -482.0
PDE6G -232.0
OR4C15 -149.0
OPN1SW -141.0
OR4E2 -123.0
OR13G1 -58.0
OR8S1 -42.0
CABP2 37.0
OR8B8 107.0
OR10H4 149.0
SCNN1A 153.0
SCNN1B 200.0
OR4D10 214.0
OR6C68 383.0
OR10W1 409.0
CAPZB 419.0
EZR 432.0
LRP8 472.0
OR13A1 488.0
OR6P1 560.0
OR1J4 581.0
WHRN 735.0
OR2M4 736.0
TMC1 811.0
OR12D2 821.0
OR9Q1 918.0
ITPR3 994.0
OR7C1 998.0
BCO2 1013.0
NAPEPLD 1049.0
LRAT 1088.0
OR5D13 1124.0
OR2M2 1153.0
OR5AP2 1238.0
OR8B12 1367.0
TRPM4 1383.0
OR7G1 1429.0
OR13C9 1432.0
CYP4V2 1470.0
OR51I1 1662.0
CACNB2 1675.0
OR4X2 1738.0
RGS9 1811.0
SPTBN1 1819.0
PDE6B 1820.0
OR2V2 1891.0
OR2T3 1981.0
PRKCQ 1984.0
OR14I1 2155.0
OR56A3 2185.0
ESPN 2467.0
OR4K17 2546.0
OR1L8 2663.0
GNAT3 2888.0
VAMP2 2995.0
OR4F15 3010.0
SDC3 3088.0
SNAP25 3092.0
APOA2 3105.0
OR2L3 3213.0
OR10G3 3235.0
OR6C2 3237.0
OR8U3 3287.0
OR4K5 3396.0
DHRS9 3429.0
OR7G2 3449.0
GRK4 3555.0
TPRN 3570.0
OR10A7 3722.0
GPC1 3792.0
OR6M1 3844.0
OR2L8 3857.0
OR8J1 3866.0
OR11G2 3913.0
OR9I1 3998.0
OR13F1 4083.0
OR4C16 4143.0
METAP1 4185.0
TWF1 4211.0
SDC4 4216.0
FNTB 4307.0
SLC26A5 4317.0
LHFPL5 4340.0
OR52J3 4401.0
LDB1 4472.0
APOE 4556.0
OR8K1 4591.0
GNB5 4614.0
PRKCA 4876.0
OR5F1 4877.0
OR4L1 4885.0
OR4A47 5010.0
OR3A2 5015.0
OR14C36 5076.0
TAS2R14 5162.0
ADCY3 5263.0
OR8K3 5323.0
OR51E2 5347.0
OR8J3 5472.0
AKR1C4 5713.0
GUCY2D 5768.0
OR4D5 5807.0
OR52E4 5812.0
OR6C1 5916.0
OR6S1 5939.0
OR2G6 5952.0
OR5H6 6022.0
GUCA1B 6038.0
CHRNA10 6052.0
SDC2 6188.0
OR5H2 6315.0
DHRS3 6431.0
DNAJC5 6484.0
RDH11 6502.0
OR1D2 6515.0
TTR 6572.0
AKR1C3 6575.0
AKR1B10 6623.0
SCNN1G 6629.0
KCNMB1 6660.0
OR2A2 6726.0
OR10G8 6753.0
OR13J1 6802.0
OR5I1 6828.0
OR52I2 6900.0
OR1A2 6957.0
OR2B11 6959.0
OR4B1 6998.0
RIPOR2 7014.0
OR1S2 7049.0
OR5M9 7074.0
OR2K2 7088.0
APOB 7093.0
AGRN 7105.0
TAS2R30 7127.0
TAS2R1 7175.0
OR52B6 7211.0
OR3A3 7237.0
HSD17B1 7247.0
OR52E8 7248.0
OR4C6 7268.0
OR52A1 7455.0
OR5L1 7498.0
OR1L1 7513.0
OR7D2 7572.0
OR52N2 7577.0
OR6F1 7717.0
OR10G9 7748.0
OR6K6 7761.0
GNB3 7772.0
TAS2R7 7780.0
OR5V1 7831.0
OR4D1 7915.0
OR13C4 7927.0
OR13C8 7963.0
OR6C76 7972.0
OR1L6 8006.0
OR4A15 8038.0
OR1L4 8042.0
PLCB2 8065.0
OR5M11 8154.0
OR4K2 8200.0
OR1L3 8252.0
OR1K1 8264.0
TAS2R50 8265.0
GRK7 8329.0
OR51A7 8357.0
OR51A2 8429.0
TAS2R20 8430.0
OR2T11 8431.0
OR4N5 8450.0
OR1E1 8476.0
OR2W3 8480.0
OR4D2 8511.0
TAS2R10 8565.0
CIB2 8580.0
OR10AD1 8581.0
OR2L2 8584.0
OR2F1 8640.0
OR5M8 8688.0
OR5D16 8693.0
OR5AC2 8727.0
OTOP1 8748.0
OR5D18 8805.0
OR4K15 8830.0
OR52K2 8898.0
OR5K3 8902.5
OR2T27 8908.0
OR11H6 9028.0
OR5H15 9055.0
OR10A3 9081.0
OR4A16 9173.0
OR4S1 9196.0
TAS2R31 9211.0
TAS2R46 9224.0
OR4K1 9233.0
OR6C75 9236.0
OR2T6 9399.0
OR3A1 9431.0
OR4K14 9439.0
GNGT1 9442.0
OR4K13 9466.0
OR14A16 9538.0
OR2G2 9584.0
OR5K1 9633.0
OR5K2 9638.0
OR10T2 9694.0
OR4C12 9765.0
OR5H1 9775.0
OR7E24 9815.0


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 5.31e-08
s.dist 0.0886
p.adjustANOVA 4.36e-05



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF738 9767
ZNF484 9635
ZNF350 9542
CTSK 9490
SUZ12 9441
ZNF611 9345
AGRP 9331
CCNT1 9273
ZNF737 9227
AGO1 9194
ZFP14 9193
ZNF273 9155
BMI1 9147
ZNF430 9144
VENTX 9131
PIP4K2B 9086
H3C1 9085
SNRPE 9065
ZNF658 8989
ZNF418 8980

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF738 9767.0
ZNF484 9635.0
ZNF350 9542.0
CTSK 9490.0
SUZ12 9441.0
ZNF611 9345.0
AGRP 9331.0
CCNT1 9273.0
ZNF737 9227.0
AGO1 9194.0
ZFP14 9193.0
ZNF273 9155.0
BMI1 9147.0
ZNF430 9144.0
VENTX 9131.0
PIP4K2B 9086.0
H3C1 9085.0
SNRPE 9065.0
ZNF658 8989.0
ZNF418 8980.0
CCN2 8957.0
H2AZ2 8952.0
ZNF197 8895.0
RETN 8894.0
DLX6 8859.0
DDX39B 8852.0
ZNF135 8823.0
CDKN2B 8810.0
PIP4K2C 8803.0
COX19 8793.0
POLR2G 8755.0
ZNF124 8740.0
ZNF564 8739.0
NR1H2 8734.0
ZNF486 8716.0
ING5 8712.0
RBL2 8703.0
ZNF222 8691.0
ZNF202 8656.0
ZNF92 8652.0
NOTCH2 8639.0
ZNF562 8634.0
ZNF860 8607.0
ANAPC15 8606.0
ZNF589 8597.0
H2BC17 8591.0
H4C12 8556.0
ZNF114 8535.0
SARNP 8527.0
PSMD13 8524.0
ZNF214 8441.0
CASP10 8392.0
ZNF493 8317.0
ZNF383 8311.0
ZNF724 8303.0
PMS2 8296.0
ZNF43 8287.0
DEK 8262.0
CTDP1 8261.0
ZNF563 8257.0
GRIA2 8214.0
H4C5 8212.0
ZNF517 8195.0
ZNF587 8172.0
ZNF558 8156.0
PHF20 8130.0
ZNF454 8126.0
LAMTOR3 8110.0
IGFBP3 8092.0
RXRG 8087.0
CREBBP 8084.0
LEF1 8081.0
PRKAB1 8054.0
ZNF112 8031.0
HIPK1 8029.0
SMURF2 8023.0
ZNF300 7980.0
KMT2D 7924.0
RGCC 7914.0
ZNF337 7911.0
ZNF680 7845.0
RNF34 7837.0
TFDP2 7789.0
ZNF716 7755.0
IWS1 7752.0
ZNF660 7751.0
CAT 7746.0
HDAC4 7743.0
SNAPC4 7734.0
ZNF714 7733.0
CASP1 7730.0
PPP2R1B 7726.0
PSMF1 7714.0
ZNF394 7707.0
ZNF689 7694.0
SNRPF 7677.0
RBX1 7648.0
PIDD1 7647.0
RPA3 7645.0
ZNF133 7633.0
ZNF264 7630.0
MAPK14 7626.0
ZNF772 7609.0
ZNF596 7602.0
CBX5 7575.0
PCBP4 7569.0
SPI1 7554.0
ZNF699 7552.0
PF4 7540.0
CDC7 7461.0
PDPK1 7458.0
BNIP3L 7448.0
ERCC3 7445.0
ZNF263 7437.0
BGLAP 7413.0
ZNF749 7402.0
ZKSCAN7 7387.0
ZNF226 7378.0
MEAF6 7374.0
ZNF416 7369.0
ZFP37 7358.0
FOS 7336.0
HDAC1 7322.0
MGA 7313.0
CDK1 7310.0
PSMD11 7309.0
H2BC9 7299.5
H3C7 7299.5
ZNF200 7294.0
TCF7 7254.0
RPA1 7231.0
SETD1A 7225.0
BRPF3 7223.0
ZNF154 7195.0
ZNF286A 7179.0
MTOR 7178.0
ARNT 7172.0
TXNIP 7168.0
ZNF549 7154.0
BID 7145.0
LSM10 7140.0
HDAC3 7126.0
HUS1 7120.0
ANAPC5 7097.0
ATXN3 7075.0
TCF3 7064.0
ZNF676 7060.0
ZNF460 7050.0
DGCR8 7026.0
SKI 7020.0
BTG1 7016.0
LAMTOR4 7004.0
ZNF18 6979.0
PPARG 6934.0
ZNF600 6932.0
COL1A2 6930.0
ZNF777 6925.0
ZNF626 6918.0
ZNF100 6906.0
PSME4 6905.0
ZFP2 6898.0
ZNF347 6879.0
PSMA2 6867.0
ATR 6854.0
KAT2A 6840.0
PRKAB2 6829.0
ZNF234 6822.0
ZNF773 6810.0
GPAM 6808.0
SYMPK 6804.0
PIP4K2A 6788.0
LGALS3 6759.0
TGIF2 6758.0
ZKSCAN4 6741.0
ZNF519 6738.0
TAF11 6725.0
TNRC6C 6711.0
CDC40 6706.0
DYRK2 6703.0
CTLA4 6701.0
PSMC6 6685.0
ZNF496 6661.0
ZNF317 6656.0
ZNF597 6642.0
CTR9 6622.0
ZKSCAN8 6620.0
ZNF649 6611.0
TAF8 6610.0
PARP1 6591.0
ZNF761 6586.0
MAPKAP1 6583.0
ZNF585A 6573.0
NR2F1 6561.0
ZNF559 6556.0
SYT10 6523.0
AURKB 6511.0
ATAD2 6435.0
GEM 6434.0
RB1 6397.0
ITGA4 6368.0
TFAP2A 6366.0
TFDP1 6358.0
CBX2 6305.0
PSMB6 6285.0
HEY2 6252.0
ZNF253 6246.0
AKT2 6231.0
ZC3H11A 6223.0
ZNF750 6221.0
LAMTOR1 6216.0
ZNF436 6212.0
SSRP1 6203.0
ZNF708 6191.0
CTSL 6187.0
POLDIP3 6169.0
RICTOR 6152.0
POLR2B 6148.0
ZNF354A 6120.0
GTF2E2 6119.0
KMT2C 6099.0
TAF3 6089.0
GTF2A1 6082.0
PITX2 6078.0
ZNF79 6044.0
JMY 6041.0
ZNF354B 6035.0
ZNF624 6024.0
H4C3 6009.0
TSC2 5999.0
YEATS4 5980.0
TAF5 5949.0
PPM1A 5941.0
KRBOX5 5938.0
ZNF557 5929.0
TWIST2 5918.0
NR4A2 5917.0
TP53I3 5913.0
ZNF667 5905.0
RFFL 5877.0
ELF1 5860.0
H2BC12 5854.0
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ZNF727 5798.0
SESN3 5747.0
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TOP3A 5734.0
ZNF664 5732.0
MED25 5727.0
INTS9 5725.0
TFAP2B 5723.0
PPARGC1A 5699.0
FOXO3 5693.0
ZNF543 5689.0
BCL2L11 5686.0
H2AC4 5676.0
ZNF189 5673.0
ZFPM1 5650.0
ZNF669 5642.0
EZH2 5620.0
ZNF684 5618.0
ZNF140 5605.0
ZNF671 5600.0
POLR2A 5585.0
H2AC20 5583.0
MIR137 5577.0
RMI2 5558.0
H3C8 5547.0
SERPINE1 5533.0
PPARA 5527.0
KCTD6 5517.0
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NR2E1 5474.0
PSMD9 5439.0
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CSNK2B 5425.0
MDM4 5418.0
ZNF771 5413.0
ZNF577 5396.0
PCGF6 5373.0
ZNF726 5370.0
ESR1 5343.0
RPTOR 5338.0
ZNF569 5337.0
H4C9 5306.0
NR2E3 5292.0
ZNF567 5289.0
NELFE 5285.0
PRDM1 5270.0
CCNA2 5259.0
ZNF791 5257.0
WDR5 5255.0
ZNF778 5246.0
BRPF1 5199.0
MYB 5194.0
ANAPC10 5142.0
ZNF75A 5141.0
TBX5 5132.0
PSMD7 5071.0
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MED27 5018.0
ITCH 5014.0
MED7 5001.0
U2AF1L4 4998.0
PRKCB 4990.0
ZNF26 4988.0
IGFBP1 4974.0
CCND3 4969.0
SRSF11 4968.0
TP53BP2 4945.0
ZNF665 4931.0
THOC5 4928.0
TAF15 4927.0
ASH2L 4906.0
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PSMB7 4896.0
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TAF1L 4541.0
NFYB 4531.0
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PPP2R5C 4507.0
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TCF12 4327.0
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ZNF169 4323.0
AKT3 4319.0
ZNF215 4304.0
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UBE2I 4284.0
YAF2 4269.0
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ZNF311 4217.0
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ZNF548 4108.0
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TAF12 4104.0
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ZNF770 4084.0
RARA 4076.0
L3MBTL2 4072.0
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ZNF461 4066.0
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ZNF195 3968.0
NFYC 3963.0
ZNF573 3945.0
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ZNF735 3917.0
ZNF23 3858.0
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PSMD14 3838.0
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H2BC7 3829.5
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ZNF248 3728.0
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ZNF2 3606.0
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EIF4A3 3582.0
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SMAD1 3494.0
TFAP2C 3482.0
ZFP69 3481.0
SETD1B 3446.0
ZNF268 3422.0
ATM 3411.0
POLR2H 3403.0
ELOA 3366.0
DLX5 3361.0
HEY1 3344.0
ZNF175 3332.0
MAML1 3323.0
FOXG1 3256.0
SNAPC2 3245.0
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CDK7 3219.0
RSPO3 3216.0
ZNF287 3210.0
BDNF 3207.0
CDC73 3203.0
BRD1 3193.0
GAMT 3189.0
TAF9 3178.0
SGK1 3113.0
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H2AC18 3107.5
H2AC19 3107.5
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DHX38 3071.0
ZNF331 3064.0
EED 3060.0
NPAS4 3052.0
ZNF662 3036.0
PSMD12 3007.0
ZNF3 3004.0
ZNF420 2975.0
CCNK 2952.0
CNOT6 2931.0
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POU2F1 2865.0
H4C16 2844.0
GTF2F1 2819.0
FANCD2 2813.0
ZNF221 2799.0
ZNF227 2796.0
NR5A2 2788.0
MAML2 2775.0
GAD1 2773.0
ZKSCAN3 2749.0
ZNF606 2747.0
ZNF70 2738.0
TRPC3 2711.0
CNOT4 2708.0
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FZR1 2630.0
CEBPB 2627.0
PSMA4 2616.0
ZNF230 2605.0
ZNF20 2600.0
ZNF136 2590.0
GADD45A 2583.0
ZNF426 2550.0
PSME1 2536.0
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TP73 2504.0
HDAC7 2503.0
EHMT1 2495.0
HNF4A 2486.0
ZNF45 2481.0
MSX2 2480.0
E2F5 2468.0
INTS6 2455.0
LAMTOR2 2452.0
ZNF774 2449.0
CBX4 2447.0
SOX9 2446.0
ZNF471 2442.0
ZNF682 2428.0
BRIP1 2420.0
PINK1 2414.0
EHMT2 2400.0
GTF2F2 2390.0
EXO1 2346.0
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BRD2 2319.0
PML 2311.0
ZNF425 2309.0
NCBP2 2289.0
ZNF14 2273.0
H3C11 2270.0
RABGGTA 2269.0
ZNF700 2242.0
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SIN3B 2221.0
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CYCS 2192.0
ZNF677 2162.0
ARID2 2145.0
FKBP5 2143.0
MOBP 2135.0
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CDK2 2115.0
ZNF740 2112.0
ZNF793 2064.0
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ZNF875 2021.0
SPP1 2012.0
PRKCQ 1984.0
ZNF28 1976.0
ZNF267 1965.0
CHD3 1941.0
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TMEM219 1917.0
ZNF560 1914.0
CLDN5 1913.0
BMP2 1904.0
SMARCA4 1900.0
H3C6 1887.0
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CRADD 1870.0
TSC1 1856.0
RPS27A 1837.0
ITGA5 1836.0
CDK8 1831.0
PPP2CA 1817.0
PPP1R13B 1815.0
TNRC6A 1810.0
ZNF529 1808.0
CDC27 1790.0
NCOR2 1788.0
PLK2 1785.0
PPP1R13L 1784.0
MRE11 1757.0
OCLN 1722.0
RNF2 1715.0
ZNF490 1690.0
ZNF746 1672.0
ITGBL1 1650.0
TIGAR 1631.0
GATA4 1616.0
RBFOX3 1613.0
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LAMTOR5 1572.0
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NFE2 1516.0
ZNF211 1509.0
GAD2 1486.0
ZNF621 1473.0
CENPJ 1469.0
NRBF2 1442.0
ZNF33A 1433.0
ZNF530 1416.0
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ZNF441 1356.0
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TP63 1323.0
ZNF25 1283.0
NELFB 1278.0
ZNF605 1256.0
SNW1 1236.0
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H3C2 1183.0
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PCF11 1140.0
BRCA1 1137.0
INTS8 1097.0
ZNF786 1094.0
PPM1D 1065.0
GSK3B 1036.0
FANCI 1032.0
ZNF143 1029.0
CNOT11 974.0
WDR33 952.0
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LMO2 904.0
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ZNF160 872.0
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RNF111 856.0
ZNF19 850.0
RPA2 810.0
RORB 793.0
ZNF568 773.0
ZNF324B 768.0
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ZKSCAN5 721.0
ZNF555 714.0
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CDC23 687.0
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ZNF398 659.0
LIFR 641.0
TP53INP1 640.0
CSTF3 611.0
TFAP2D 583.0
PLXNA4 582.0
PSMD6 572.0
PSMC3 570.0
ZNF324 561.0
SRC 550.0
HES1 542.0
CHEK1 534.0
PSMB2 533.0
SCO1 523.0
MIR132 495.0
GATAD2B 485.0
INTS3 471.0
ZNF675 466.0
PSMD8 460.0
ZNF641 435.0
PRDX5 408.0
FANCC 405.0
ELL2 395.0
ZNF213 373.0
TNFRSF10B 346.0
PSMA3 337.0
PHC1 323.0
RYBP 314.0
RFC3 302.0
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EAF2 279.0
HDAC11 276.0
E2F1 271.0
CSTF1 267.0
INTS13 238.0
ZNF343 230.0
SRSF5 226.0
CHTOP 220.0
SREBF1 216.0
RRAGA 215.0
YWHAG 201.0
ZFP1 195.0
MAGOHB 192.0
PSMD5 170.0
UBE2D1 159.0
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NR4A3 147.0
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ZNF257 96.0
PRDM7 90.0
ZNF551 83.0
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ZNF429 45.0
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EP300 15.0
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ZFP28 -22.0
NELFA -54.0
ZNF582 -63.0
ZNF184 -64.0
HIVEP3 -70.0
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ZNF138 -87.0
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ZNF547 -187.0
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ZNF607 -314.0
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ZNF703 -349.0
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ZNF776 -460.0
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ZNF713 -636.0
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ZNF655 -769.0
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ZNF785 -1110.0
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ZNF721 -1491.0
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ZNF250 -1891.0
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ZNF764 -2306.0
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ING2 -6277.0
ZNF74 -6279.0
ZFP69B -6280.0
ESRRB -6291.0
ZNF528 -6303.0
ZNF473 -6309.0
NR1H4 -6356.0
POLR2E -6392.0
NFATC2 -6394.0
SRRT -6399.0
KMT2E -6402.0
H2BC1 -6416.0
ZNF556 -6418.0
SRSF7 -6436.0
RBL1 -6448.0
YWHAB -6461.0
CBX6 -6482.0
NAMPT -6505.0
MED1 -6506.0
PGR -6524.0
L3MBTL1 -6527.0
UBB -6535.0
MED6 -6544.0
PIN1 -6552.0
VDR -6563.0
KMT2A -6565.0
SP7 -6602.0
ZNF561 -6612.0
LBR -6626.0
NPM1 -6656.0
NR1I3 -6664.0
HDAC9 -6719.0
CGA -6754.0
COX20 -6769.0
ZNF385A -6771.0
H2BC11 -6780.0
PERP -6798.0
H2BC26 -6814.0
TAF7 -6840.0
MED4 -6843.0
DDIT3 -6845.0
JAG1 -6851.0
ZNF550 -6884.0
KCTD15 -6887.0
PSMC1 -6897.0
THBS1 -6908.0
TOPBP1 -6914.0
GTF2B -6934.0
TNKS1BP1 -6950.0
SRSF2 -7010.0
H4C2 -7011.0
RPAP2 -7025.0
CSNK2A1 -7041.0
ZNF101 -7046.0
CPSF2 -7087.0
ZNF718 -7102.0
ZNF540 -7103.0
CNOT8 -7138.0
RARB -7171.0
ICE1 -7182.0
COX6A1 -7189.0
FAS -7195.0
POLR2L -7198.0
PRKACA -7200.0
NDRG1 -7203.0
ZNF717 -7211.0
KCNIP3 -7231.0
COX5A -7237.0
CCNA1 -7274.0
ZKSCAN1 -7300.0
UBE2S -7305.0
UBC -7308.0
PRKAG1 -7330.0
GTF2E1 -7352.0
ZNF583 -7357.0
H2AZ1 -7369.0
ZNF417 -7371.0
EGFR -7397.0
RBM8A -7442.0
THOC7 -7449.0
TNFRSF10C -7453.0
RELA -7456.0
CGB8 -7462.0
SUMO1 -7473.0
PSME3 -7475.0
ZNF678 -7493.0
CCNH -7497.0
TAF6 -7548.0
UCMA -7557.0
CASP2 -7562.0
CCNE2 -7568.0
ZNF614 -7588.0
PSMB4 -7626.0
DDX39A -7700.0
SIRT1 -7713.0
SLBP -7714.0
PSMC5 -7743.0
PRELID1 -7744.0
GRIN2A -7810.0
NR6A1 -7836.0
TEAD2 -7864.0
GPX2 -7865.0
RNU12 -7898.0
SMARCE1 -7900.0
HSPD1 -7935.0
ARNT2 -7944.0
H3-3B -7982.0
ZNF480 -8013.0
NFKB1 -8019.0
KAT5 -8090.0
POLR2K -8099.0
UBA52 -8101.0
SNRPD3 -8107.0
ZNF470 -8124.0
CAMK2B -8137.0
BCL2L14 -8178.0
NR1H3 -8193.0
POU4F1 -8235.0
TAF13 -8245.0
MLST8 -8255.0
ZNF610 -8259.0
MED31 -8262.0
COX4I1 -8275.0
CREB1 -8293.0
YAP1 -8336.0
ZNF442 -8343.0
PABPN1 -8344.0
CNOT3 -8350.0
TP53 -8352.0
RBM14 -8383.0
SRSF4 -8393.0
SIRT3 -8402.0
NPY -8526.0
RNMT -8540.0
HNF4G -8541.0
ZNF212 -8542.0
ZNF552 -8552.0
APAF1 -8553.0
LSM11 -8630.0
CDK4 -8679.0
RBBP5 -8717.0
GP1BA -8765.0
H2AC8 -8778.0
YBX1 -8800.0
MSTN -8802.0
SLC2A3 -8849.0
NELFCD -8903.0
USP2 -8908.0
RET -8942.0
MTA2 -9053.0
H2BC8 -9079.0
CCNG1 -9204.0
UBE2C -9239.0
DAXX -9294.0
COX8A -9299.0
RBBP8 -9329.0
ZNF205 -9342.0
INTS5 -9357.0
CNOT2 -9384.0
MED26 -9421.0
PAF1 -9433.0
MAGOH -9442.0
MIR27A -9476.0
COX14 -9480.0
ATRIP -9488.0
COX5B -9494.0
USP7 -9538.0
ZNF625 -9544.0
KMT5A -9545.0
NR1D2 -9604.0
SURF1 -9606.0
TPX2 -9621.0
GLI2 -9655.0
LMO1 -9727.0
E2F4 -9759.0
ZNF730 -9763.0
SOD2 -9781.0
PLK3 -9811.0
JUNB -9818.0
TRIM28 -9819.0
TCEA1 -9843.0
E2F7 -9892.0
DLL1 -9898.0
POLR2F -9908.0
CDC16 -9923.0
H2BC14 -9980.0
MIR24-2 -9991.0
H3C10 -10013.0
NPPA -10027.0
PRKAG3 -10028.0
H2AC14 -10060.0
SKP1 -10072.0
ZNF233 -10148.0
CCNG2 -10150.0
PSMB10 -10166.0
RHNO1 -10241.0
TP53AIP1 -10284.0
MED20 -10306.0
MAPKAPK5 -10315.0
FOXO6 -10350.0
ZNF679 -10380.0
RAD1 -10381.0
RAD50 -10384.0
NLRC4 -10413.0
RTF1 -10427.0
CPSF6 -10434.0
ZNF571 -10547.0
ELOA2 -10549.0
PRMT1 -10582.0
ZNF586 -10648.0
STEAP3 -10651.0
IFNG -10672.0
CR1 -10697.0
NR4A1 -10711.0
ABCA6 -10718.0
PCK1 -10749.0
MYBL2 -10760.0
ZNF431 -10784.0
SKIL -10825.0
TRIM63 -10860.0
SCO2 -10874.0
THOC3 -10875.0
PTPN11 -10878.0
PPP2CB -10912.0
H3C12 -10932.0
ZNF34 -10951.0
ZNF691 -10952.0
KLF4 -10956.0
ZNF736 -11007.0
FASLG -11169.0
G6PC1 -11200.0
HDAC10 -11215.0
CAMK2A -11296.0
ZNF506 -11332.0
SFN -11352.0
KMT2B -11378.0
IL2 -11513.0
ZNF320 -11592.0
PSMB11 -11624.0
ZNF419 -11639.0
ZNF595 -11749.0
CSF2 -11790.0
ZNF732 -11940.0
ZNF468 -11957.0
IL3 -12113.0


REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 1.24e-05
s.dist -0.247
p.adjustANOVA 0.00519



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
SEC11C -10921.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
SPCS2 -10400.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
SRPRA -10009.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
SEC11C -10921.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
SPCS2 -10400.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
SRPRA -10009.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
SPCS1 -9704.0
RPL37 -9383.0
RPL38 -9338.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
SRP14 -8243.0
UBA52 -8101.0
RPL35A -7809.0
RPS25 -7758.0
RPS5 -7280.0
RPN1 -7150.0
RPS13 -7029.0
RPS6 -6939.0
SEC11A -6713.0
RPL13 -6617.0
RPS20 -6260.0
RPN2 -6071.0
SRP72 -6008.0
RPL41 -5634.0
RPS21 -5458.0
RPL23A -5311.0
RPS24 -5072.0
RPL39L -5003.0
SSR1 -4861.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
RPL3L -4049.0
RPL6 -4047.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
SRP68 -3675.0
SRPRB -3635.0
SEC61B -3524.0
RPL30 -3513.0
SRP19 -3258.0
RPL35 -3180.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
RPS3 -1606.0
SPCS3 -1338.0
RPL22 -1193.0
SRP9 -1185.0
RPS29 -1088.0
RPL17 -837.0
SSR2 -604.0
RPL5 -544.0
RPS11 -225.0
RPL26 -28.0
RPL27A 454.0
DDOST 699.0
SEC61A2 874.0
RPL19 1027.0
RPL11 1163.0
TRAM1 1185.0
RPS16 1311.0
RPS27A 1837.0
RPLP1 2863.0
RPL34 3847.0
SRP54 4132.0
RPS9 4427.0
RPL37A 4707.0
RPL15 5290.0
SSR3 5326.0
RPL26L1 5864.0
SEC61G 6090.0
SEC61A1 6443.0
RPL32 7009.0
RPS19 7158.0
RPS27 7711.0
RPS14 8094.0
RPL31 8401.0
RPL10L 9197.0


REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 1.26e-05
s.dist -0.136
p.adjustANOVA 0.00519



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR56B4 -12153
OR51B6 -12101
OR4D11 -12082
OR52E2 -12073
OR10Z1 -12069
OR2AG1 -12068
OR52E6 -12056
OR8B4 -12048
OR10J3 -12045
OR56A1 -12010
OR2L5 -11976
OR51F1 -11924
OR5C1 -11896
OR5T3 -11885
OR51G2 -11734
OR2S2 -11728
OR51S1 -11725
OR51T1 -11684
OR10G4 -11675
OR4N2 -11647

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR56B4 -12153.0
OR51B6 -12101.0
OR4D11 -12082.0
OR52E2 -12073.0
OR10Z1 -12069.0
OR2AG1 -12068.0
OR52E6 -12056.0
OR8B4 -12048.0
OR10J3 -12045.0
OR56A1 -12010.0
OR2L5 -11976.0
OR51F1 -11924.0
OR5C1 -11896.0
OR5T3 -11885.0
OR51G2 -11734.0
OR2S2 -11728.0
OR51S1 -11725.0
OR51T1 -11684.0
OR10G4 -11675.0
OR4N2 -11647.0
OR2AT4 -11641.0
OR8G5 -11611.0
OR56B1 -11604.0
OR10P1 -11596.0
OR13D1 -11563.0
OR2H1 -11558.0
OR10X1 -11533.0
OR8D2 -11499.0
OR10G2 -11496.0
OR5B3 -11489.0
OR10H2 -11482.0
OR5P3 -11457.0
OR51B4 -11435.0
OR51F2 -11431.0
OR6N2 -11422.0
OR4D6 -11405.0
OR5A1 -11395.0
OR2M7 -11394.0
OR5A2 -11370.0
OR5T2 -11367.0
OR6Y1 -11359.0
OR51B2 -11341.0
OR5P2 -11336.0
OR8H3 -11326.0
OR10J1 -11319.0
OR52R1 -11307.0
OR2C3 -11289.0
OR2J2 -11273.0
OR2V1 -11265.0
OR52A5 -11153.0
OR7D4 -11110.0
OR51G1 -11104.0
OR51V1 -11092.0
OR6C74 -11090.0
OR6B1 -11088.0
OR52B2 -11077.0
OR10V1 -11060.0
OR11H4 -11043.0
OR6B3 -11005.0
RTP2 -10992.0
OR5AK2 -10931.0
OR6C4 -10853.0
OR2T12 -10835.0
OR6C65 -10792.0
OR8B2 -10779.0
OR10H5 -10772.0
OR5T1 -10736.0
OR9G4 -10693.0
OR8K5 -10681.0
OR51E1 -10653.0
OR2Y1 -10589.0
OR51Q1 -10539.0
OR6X1 -10423.0
OR10J5 -10327.0
OR9A2 -10309.0
OR52I1 -10292.0
OR2AG2 -10212.0
OR6C6 -10206.0
OR5K4 -10163.0
OR5D14 -10125.0
OR2T33 -10116.0
OR5W2 -9953.0
OR2D3 -9942.0
OR6K2 -9934.0
OR10A4 -9881.0
OR13C2 -9774.0
OR51B5 -9744.0
OR51D1 -9653.0
ANO2 -9650.0
OR5M10 -9620.0
OR2D2 -9610.0
OR1E2 -9571.0
OR4C46 -9534.0
OR6K3 -9527.0
OR10C1 -9435.0
OR8I2 -9434.0
OR8U1 -9389.0
OR8G1 -9367.0
OR10H3 -9243.0
OR52W1 -9162.0
OR2B2 -9057.0
OR52K1 -8976.0
OR4X1 -8958.0
OR6B2 -8921.0
OR5AS1 -8884.0
OR5B12 -8861.0
OR10K2 -8784.0
OR12D3 -8757.0
OR5AN1 -8695.0
OR9G1 -8668.5
OR9G9 -8668.5
OR6C70 -8602.0
OR52D1 -8593.0
OR1A1 -8493.0
OR10A6 -8325.0
OR7C2 -8305.0
OR5M3 -8269.0
CNGB1 -8214.0
OR2A14 -8172.0
OR6N1 -8142.0
OR5L2 -8110.0
OR6A2 -8106.0
OR5AU1 -8089.0
OR10Q1 -7954.0
OR1Q1 -7890.0
OR5B21 -7883.0
OR10AG1 -7745.0
OR2G3 -7728.0
OR2M3 -7726.0
OR6V1 -7706.0
OR2AP1 -7675.0
OR2M5 -7601.0
OR52N1 -7555.0
OR1F1 -7519.0
OR4M1 -7498.0
OR5B17 -7496.0
OR7A5 -7141.0
OR1N1 -7027.0
OR1J2 -6762.0
OR51M1 -6758.0
OR4C3 -6652.0
OR51L1 -6642.0
OR1G1 -6635.0
OR2A12 -6632.0
OR1J1 -6614.0
GNG13 -6611.0
OR5J2 -6564.0
OR7A17 -6489.0
OR9A4 -6417.0
OR8A1 -6401.0
OR1M1 -6235.0
OR52L1 -6201.0
OR52H1 -6158.0
OR8U8 -6155.0
OR14J1 -6142.0
EBF1 -6009.0
CNGA4 -5981.0
OR4C45 -5927.0
OR2A5 -5882.0
OR9K2 -5763.0
OR2H2 -5600.0
OR2C1 -5461.0
OR6C3 -5390.0
OR2T4 -5221.0
OR10G7 -5135.0
OR2Z1 -4973.0
OR2B3 -4963.0
OR2AE1 -4827.0
OR11A1 -4761.0
OR1I1 -4739.0
OR10S1 -4483.0
GNB1 -4430.0
OR8D1 -4357.0
OR5AR1 -4218.0
OR56A4 -4072.0
OR7A10 -3914.0
OR2B6 -3841.0
OR2AK2 -3791.0
OR10A5 -3758.0
OR5M1 -3700.0
OR9Q2 -3651.0
GNAL -3644.0
OR4F6 -3594.0
LHX2 -3582.0
OR6T1 -3276.0
OR4D9 -3273.0
OR2F2 -3154.0
OR1C1 -3028.0
RTP1 -2943.0
OR51I2 -2925.0
OR10K1 -2863.0
REEP1 -2739.0
OR11L1 -2714.0
OR4A5 -2675.0
OR10A2 -2468.0
OR2T1 -2429.0
OR7G3 -2161.0
OR8D4 -1969.0
OR1N2 -1825.0
OR5B2 -1747.0
OR6Q1 -1587.0
OR2T8 -1279.0
OR2L13 -1249.0
OR1S1 -1107.0
OR2W1 -1092.0
OR8H1 -1013.0
OR56A5 -986.0
OR10H1 -692.0
OR52M1 -578.0
OR1B1 -561.0
OR13C3 -484.0
OR4C15 -149.0
OR4E2 -123.0
OR13G1 -58.0
OR8S1 -42.0
OR8B8 107.0
OR10H4 149.0
OR4D10 214.0
OR6C68 383.0
OR10W1 409.0
OR13A1 488.0
OR6P1 560.0
OR1J4 581.0
OR2M4 736.0
OR12D2 821.0
OR9Q1 918.0
OR7C1 998.0
OR5D13 1124.0
OR2M2 1153.0
OR5AP2 1238.0
OR8B12 1367.0
OR7G1 1429.0
OR13C9 1432.0
OR51I1 1662.0
OR4X2 1738.0
OR2V2 1891.0
OR2T3 1981.0
OR14I1 2155.0
OR56A3 2185.0
OR4K17 2546.0
OR1L8 2663.0
OR4F15 3010.0
OR2L3 3213.0
OR10G3 3235.0
OR6C2 3237.0
OR8U3 3287.0
OR4K5 3396.0
OR7G2 3449.0
OR10A7 3722.0
OR6M1 3844.0
OR2L8 3857.0
OR8J1 3866.0
OR11G2 3913.0
OR9I1 3998.0
OR13F1 4083.0
OR4C16 4143.0
OR52J3 4401.0
LDB1 4472.0
OR8K1 4591.0
OR5F1 4877.0
OR4L1 4885.0
OR4A47 5010.0
OR3A2 5015.0
OR14C36 5076.0
ADCY3 5263.0
OR8K3 5323.0
OR51E2 5347.0
OR8J3 5472.0
OR4D5 5807.0
OR52E4 5812.0
OR6C1 5916.0
OR6S1 5939.0
OR2G6 5952.0
OR5H6 6022.0
OR5H2 6315.0
OR1D2 6515.0
OR2A2 6726.0
OR10G8 6753.0
OR13J1 6802.0
OR5I1 6828.0
OR52I2 6900.0
OR1A2 6957.0
OR2B11 6959.0
OR4B1 6998.0
OR1S2 7049.0
OR5M9 7074.0
OR2K2 7088.0
OR52B6 7211.0
OR3A3 7237.0
OR52E8 7248.0
OR4C6 7268.0
OR52A1 7455.0
OR5L1 7498.0
OR1L1 7513.0
OR7D2 7572.0
OR52N2 7577.0
OR6F1 7717.0
OR10G9 7748.0
OR6K6 7761.0
OR5V1 7831.0
OR4D1 7915.0
OR13C4 7927.0
OR13C8 7963.0
OR6C76 7972.0
OR1L6 8006.0
OR4A15 8038.0
OR1L4 8042.0
OR5M11 8154.0
OR4K2 8200.0
OR1L3 8252.0
OR1K1 8264.0
OR51A7 8357.0
OR51A2 8429.0
OR2T11 8431.0
OR4N5 8450.0
OR1E1 8476.0
OR2W3 8480.0
OR4D2 8511.0
OR10AD1 8581.0
OR2L2 8584.0
OR2F1 8640.0
OR5M8 8688.0
OR5D16 8693.0
OR5AC2 8727.0
OR5D18 8805.0
OR4K15 8830.0
OR52K2 8898.0
OR5K3 8902.5
OR2T27 8908.0
OR11H6 9028.0
OR5H15 9055.0
OR10A3 9081.0
OR4A16 9173.0
OR4S1 9196.0
OR4K1 9233.0
OR6C75 9236.0
OR2T6 9399.0
OR3A1 9431.0
OR4K14 9439.0
OR4K13 9466.0
OR14A16 9538.0
OR2G2 9584.0
OR5K1 9633.0
OR5K2 9638.0
OR10T2 9694.0
OR4C12 9765.0
OR5H1 9775.0
OR7E24 9815.0


REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 3.19e-05
s.dist -0.258
p.adjustANOVA 0.0105



Top enriched genes

Top 20 genes
GeneID Gene Rank
EEF1G -11487.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EEF1G -11487.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
RPL35A -7809.0
RPS25 -7758.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
RPL13 -6617.0
RPS20 -6260.0
EEF1B2 -5888.0
RPL41 -5634.0
RPS21 -5458.0
RPL23A -5311.0
RPS24 -5072.0
RPL39L -5003.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
RPL3L -4049.0
RPL6 -4047.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
RPL30 -3513.0
EEF1A1 -3420.0
RPL35 -3180.0
EEF2 -3111.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
RPS3 -1606.0
RPL22 -1193.0
RPS29 -1088.0
RPL17 -837.0
RPL5 -544.0
RPS11 -225.0
RPL26 -28.0
RPL27A 454.0
RPL19 1027.0
RPL11 1163.0
RPS16 1311.0
RPS27A 1837.0
RPLP1 2863.0
RPL34 3847.0
RPS9 4427.0
RPL37A 4707.0
EEF1A2 4960.0
EEF1D 5057.0
RPL15 5290.0
RPL26L1 5864.0
RPL32 7009.0
RPS19 7158.0
RPS27 7711.0
RPS14 8094.0
RPL31 8401.0
RPL10L 9197.0


REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
1082
set REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize 125
pANOVA 4.99e-05
s.dist -0.21
p.adjustANOVA 0.0137



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRT16 -12075
SPRR1B -11908
KRT78 -11859
KRT83 -11772
FLG -11766
KRT80 -11713
LELP1 -11700
KRT75 -11661
SPRR2G -11571
KRT6A -11447
TGM5 -11388
LCE3D -11167
KRT74 -11124
KRT4 -11051
KRT15 -10873
KRT71 -10847
KRT82 -10805
KRT85 -10777
LCE1B -10747
KRT18 -10699

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRT16 -12075
SPRR1B -11908
KRT78 -11859
KRT83 -11772
FLG -11766
KRT80 -11713
LELP1 -11700
KRT75 -11661
SPRR2G -11571
KRT6A -11447
TGM5 -11388
LCE3D -11167
KRT74 -11124
KRT4 -11051
KRT15 -10873
KRT71 -10847
KRT82 -10805
KRT85 -10777
LCE1B -10747
KRT18 -10699
KRT79 -10645
KRT5 -10462
SPRR2A -10448
KRT84 -10377
KRT77 -10372
LCE1E -10331
KRT76 -10289
KRT73 -10268
LCE4A -10182
LCE2B -10177
CDSN -10175
LIPJ -10138
IVL -10107
LCE3E -10044
KRT32 -10018
KRT2 -9866
LCE2A -9255
PKP3 -9211
JUP -9129
KRT27 -9123
KRT26 -8897
KRT8 -8645
KRT33B -8473
CELA2A -8190
CASP14 -8179
KRT17 -7871
KRT25 -7856
SPINK6 -7561
DSG3 -7129
PKP2 -7110
KLK14 -7040
LCE6A -6953
LCE2D -6830
PERP -6798
PKP1 -6772
PCSK6 -6479
KLK5 -6439
KRT7 -6193
SPRR2F -6116
KRT6C -5974
ST14 -5728
LCE5A -5092
KRT38 -5039
PI3 -5031
LCE1A -4153
SPINK9 -3928
KLK8 -3779
EVPL -3502
LCE1C -3119
SPINK5 -3065
TCHH -2996
SPRR1A -2964
KRT20 -2938
KRT10 -2868
KAZN -2806
KRT1 -2572
PPL -2482
KRT40 -2286
DSG4 -2009
KRT3 -1788
DSC3 -1711
FURIN -1473
DSG1 -1461
CAPN1 -697
DSP -542
KRT28 268
KRT12 363
KRT13 393
PKP4 553
KRT36 576
KLK12 1072
KRT72 1139
KLK13 1244
KRT23 2042
SPRR2D 2111
LCE3B 2667
KRT31 2928
CAPNS1 3023
DSC2 3472
LCE3A 4127
SPRR3 4249
TGM1 4252
DSG2 4938
LIPM 5377
KRT9 6080
CSTA 6104
KRT35 6200
KRT19 6471
SPRR2E 7029
KRT6B 7400
KRT37 7846
LIPN 7989
KRT86 8166
RPTN 8180
KRT24 8228
KRT33A 8277
LIPK 8695
KRT39 8724
KRT34 8914
PRSS8 8961
LCE1F 9159
KRT14 9285
KRT81 9636
LCE2C 9702
DSC1 9786


REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 0.000156
s.dist -0.212
p.adjustANOVA 0.0342



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
MAGOH -9442.0
RPL37 -9383.0
RPL38 -9338.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
MAGOH -9442.0
RPL37 -9383.0
RPL38 -9338.0
EIF4G1 -9280.0
RPL18A -9270.0
RPL14 -9085.0
SMG9 -8999.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
PPP2R2A -7857.0
RPL35A -7809.0
RPS25 -7758.0
RBM8A -7442.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
RPL13 -6617.0
RPS20 -6260.0
RPL41 -5634.0
RPS21 -5458.0
RPL23A -5311.0
PABPC1 -5303.0
RPS24 -5072.0
SMG5 -5052.0
RPL39L -5003.0
UPF2 -4889.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
ETF1 -4193.0
RPL3L -4049.0
RPL6 -4047.0
GSPT1 -4015.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
RPL30 -3513.0
CASC3 -3191.0
RPL35 -3180.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
RPS27L -2334.0
NCBP1 -2261.0
RPS26 -2128.0
RPL28 -2101.0
RPS3 -1606.0
PPP2R1A -1400.0
RPL22 -1193.0
RPS29 -1088.0
SMG8 -994.0
RPL17 -837.0
PNRC2 -758.0
RPL5 -544.0
RNPS1 -298.0
RPS11 -225.0
RPL26 -28.0
MAGOHB 192.0
RPL27A 454.0
SMG7 475.0
RPL19 1027.0
RPL11 1163.0
RPS16 1311.0
PPP2CA 1817.0
RPS27A 1837.0
NCBP2 2289.0
RPLP1 2863.0
EIF4A3 3582.0
RPL34 3847.0
RPS9 4427.0
RPL37A 4707.0
SMG1 4829.0
UPF1 4909.0
DCP1A 5167.0
SMG6 5250.0
RPL15 5290.0
RPL26L1 5864.0
RPL32 7009.0
RPS19 7158.0
RPS27 7711.0
UPF3A 7923.0
RPS14 8094.0
RPL31 8401.0
RPL10L 9197.0


REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 0.000167
s.dist -0.225
p.adjustANOVA 0.0342



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0
RPL18A -9270.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
ATF3 -8409.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
RPL35A -7809.0
RPS25 -7758.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
DDIT3 -6845.0
RPL13 -6617.0
RPS20 -6260.0
ATF4 -5994.0
ATF2 -5645.0
RPL41 -5634.0
RPS21 -5458.0
RPL23A -5311.0
RPS24 -5072.0
RPL39L -5003.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
RPL3L -4049.0
RPL6 -4047.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
RPL30 -3513.0
RPL35 -3180.0
RPL24 -2999.0
GCN1 -2927.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
TRIB3 -1981.0
RPS3 -1606.0
RPL22 -1193.0
RPS29 -1088.0
RPL17 -837.0
RPL5 -544.0
RPS11 -225.0
RPL26 -28.0
RPL27A 454.0
RPL19 1027.0
EIF2S2 1041.0
RPL11 1163.0
RPS16 1311.0
EIF2S1 1357.0
RPS27A 1837.0
CEBPB 2627.0
RPLP1 2863.0
CEBPG 3394.0
RPL34 3847.0
EIF2AK4 4382.0
RPS9 4427.0
RPL37A 4707.0
IMPACT 5016.0
RPL15 5290.0
RPL26L1 5864.0
ASNS 6580.0
RPL32 7009.0
RPS19 7158.0
RPS27 7711.0
RPS14 8094.0
RPL31 8401.0
RPL10L 9197.0


REACTOME_COMPLEMENT_CASCADE

REACTOME_COMPLEMENT_CASCADE
212
set REACTOME_COMPLEMENT_CASCADE
setSize 54
pANOVA 0.000201
s.dist -0.292
p.adjustANOVA 0.0367



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -11633.0
FCN2 -11559.0
C5AR1 -11113.0
C4A -10879.5
C4B -10879.5
CRP -10819.0
CR1 -10697.0
MASP1 -10383.0
FCN3 -10157.0
C1QB -10126.0
CPN1 -9945.0
C5AR2 -9813.0
CFI -9578.0
CFD -9361.0
C6 -9189.0
MBL2 -9077.0
ELANE -8725.0
CPN2 -8683.0
CFHR5 -7119.0
F2 -6955.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -11633.0
FCN2 -11559.0
C5AR1 -11113.0
C4A -10879.5
C4B -10879.5
CRP -10819.0
CR1 -10697.0
MASP1 -10383.0
FCN3 -10157.0
C1QB -10126.0
CPN1 -9945.0
C5AR2 -9813.0
CFI -9578.0
CFD -9361.0
C6 -9189.0
MBL2 -9077.0
ELANE -8725.0
CPN2 -8683.0
CFHR5 -7119.0
F2 -6955.0
CFHR4 -6873.0
VTN -6443.0
CD46 -6240.0
C8A -6223.0
C3 -5985.0
CR2 -5864.0
C1S -5493.0
COLEC10 -5455.0
C7 -5444.0
CPB2 -5274.0
COLEC11 -5126.0
CD55 -4870.0
CFB -4429.0
CD81 -4360.0
CFH -3648.0
MASP2 -3170.0
PROS1 -2904.0
C2 -2040.0
CD59 -901.0
C5 686.0
C3AR1 1333.0
C8B 1619.0
CD19 1628.0
C1QC 1879.0
C4BPB 1908.0
SERPING1 2098.0
C4BPA 2770.0
C1R 3059.0
GZMM 3253.0
C9 4237.0
C8G 5694.0
C1QA 6057.0
CLU 6544.0
CFHR2 9044.0


REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 0.000359
s.dist -0.197
p.adjustANOVA 0.059



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
EIF3F -10188.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
EIF3F -10188.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0
EIF4G1 -9280.0
RPL18A -9270.0
RPL14 -9085.0
EIF4EBP1 -8846.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
EIF4A1 -8223.0
UBA52 -8101.0
RPL35A -7809.0
RPS25 -7758.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
EIF4A2 -6653.0
RPL13 -6617.0
RPS20 -6260.0
EIF2B5 -5767.0
RPL41 -5634.0
RPS21 -5458.0
EIF5B -5415.0
RPL23A -5311.0
PABPC1 -5303.0
RPS24 -5072.0
RPL39L -5003.0
RPL22L1 -4795.0
RPS23 -4737.0
EIF4E -4609.0
RPL7A -4508.0
RPL3L -4049.0
RPL6 -4047.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
EIF5 -3638.0
RPL30 -3513.0
EIF3B -3238.0
RPL35 -3180.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
EIF3A -2637.0
EIF4B -2593.0
RPL9 -2423.0
EIF4H -2396.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
RPS3 -1606.0
RPL22 -1193.0
RPS29 -1088.0
EIF2B1 -1066.0
RPL17 -837.0
RPL5 -544.0
EIF3J -435.0
RPS11 -225.0
RPL26 -28.0
RPL27A 454.0
EIF2B4 840.0
RPL19 1027.0
EIF2S2 1041.0
RPL11 1163.0
RPS16 1311.0
EIF2S1 1357.0
RPS27A 1837.0
EIF3I 1968.0
EIF3K 2683.0
RPLP1 2863.0
EIF3H 2929.0
EIF3G 3122.0
EIF3D 3839.0
RPL34 3847.0
EIF3M 4354.0
RPS9 4427.0
RPL37A 4707.0
EIF2B3 5202.0
RPL15 5290.0
EIF3E 5510.0
RPL26L1 5864.0
RPL32 7009.0
RPS19 7158.0
EIF3L 7532.0
RPS27 7711.0
RPS14 8094.0
EIF2B2 8271.0
RPL31 8401.0
RPL10L 9197.0


REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
116
set REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
setSize 291
pANOVA 0.000442
s.dist -0.12
p.adjustANOVA 0.0659



Top enriched genes

Top 20 genes
GeneID Gene Rank
MMP8 -11878
PRSS1 -11874
MMP19 -11612
ITGAX -11561
CAPN13 -11500
CEACAM6 -11464
PECAM1 -11438
MMP20 -11366
TNN -11232
P3H3 -11223
PDGFB -11134
ITGAD -10966
CDH1 -10913
LRP4 -10907
MMP11 -10877
HAPLN1 -10863
BMP10 -10861
COL13A1 -10837
FBLN1 -10650
MFAP2 -10500

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MMP8 -11878
PRSS1 -11874
MMP19 -11612
ITGAX -11561
CAPN13 -11500
CEACAM6 -11464
PECAM1 -11438
MMP20 -11366
TNN -11232
P3H3 -11223
PDGFB -11134
ITGAD -10966
CDH1 -10913
LRP4 -10907
MMP11 -10877
HAPLN1 -10863
BMP10 -10861
COL13A1 -10837
FBLN1 -10650
MFAP2 -10500
CAPN12 -10496
MMP24 -10412
ITGB6 -10340
MMP1 -10285
CTSD -10276
VWF -10252
COL7A1 -10232
MUSK -10221
COL27A1 -10209
DSPP -10156
SPARC -10133
EMILIN3 -10117
COL17A1 -9936
CAPN5 -9927
TIMP2 -9890
CAPN11 -9795
COL8A2 -9750
DDR2 -9724
FBLN2 -9710
MMP17 -9447
KDR -9444
ITGA3 -9430
ADAMTS1 -9373
ITGB8 -9314
ITGB5 -9313
COL23A1 -9232
TMPRSS6 -9197
SCUBE1 -9183
ITGA7 -9152
KLK2 -9056
ITGA9 -9035
ITGB1 -9031
LAMB2 -9008
ADAMTS14 -8964
COL16A1 -8919
PLOD2 -8788
HSPG2 -8775
ICAM1 -8748
ELANE -8725
ITGA11 -8678
TRAPPC4 -8585
LAMB3 -8550
SDC1 -8387
CTRB1 -8317
ADAMTS4 -8177
MMP9 -8176
ICAM5 -8125
ADAM19 -8081
OPTC -7816
ACAN -7784
ADAMTS18 -7747
MMP12 -7671
COL9A3 -7637
ASPN -7572
PDGFA -7491
COL5A3 -7318
KLKB1 -7185
ADAMTS3 -7176
THBS1 -6908
TNXB -6899
LAMC1 -6839
COL9A2 -6827
LAMC3 -6707
CAPNS2 -6596
TLL2 -6593
VTN -6443
GDF5 -6382
MATN4 -6350
PLG -6247
LUM -6182
ADAMTS2 -6086
LTBP1 -6080
P3H1 -6037
FBN1 -5910
CAPN9 -5850
ITGA10 -5753
TNR -5736
ITGB4 -5724
MMP16 -5624
CAPN7 -5609
LOX -5552
P4HB -5517
EFEMP2 -5420
ELN -5410
MADCAM1 -5342
HTRA1 -5322
COL20A1 -5297
COL14A1 -5205
DST -5184
ITGA2 -5134
NID1 -5124
CEACAM8 -5118
NTN4 -5087
CMA1 -4997
COL22A1 -4940
ITGA1 -4865
CTRB2 -4608
LTBP2 -4553
COL15A1 -4529
CAPN14 -4470
MFAP3 -4390
CD47 -4311
NCSTN -4289
TGFB1 -4255
ADAM9 -4176
F11R -4149
FGG -3975
MMP2 -3801
CTSG -3799
COL28A1 -3757
P3H2 -3689
ADAMTS9 -3685
COL1A1 -3665
COL11A2 -3555
FGB -3453
ADAMTS5 -3373
COL4A4 -3267
LAMA4 -3243
COL4A2 -3113
COL6A3 -3107
APP -3074
TNC -3034
COL5A2 -2914
NCAN -2753
LOXL1 -2752
PCOLCE2 -2531
MATN1 -2519
P4HA3 -2518
ITGA2B -2492
ADAM15 -2449
MMP13 -2272
LTBP4 -2266
COL11A1 -2196
CTSV -2142
CAPN8 -2141
COL9A1 -2035
BMP4 -1955
ADAMTS16 -1949
LTBP3 -1906
LAMA5 -1833
P4HA2 -1807
CAPN2 -1758
LOXL4 -1679
ITGAL -1515
FURIN -1473
SH3PXD2A -1462
CAST -1413
COL8A1 -1267
KLK7 -1195
COL5A1 -1138
TGFB2 -1040
FN1 -1014
MFAP5 -857
LAMA2 -855
COL24A1 -830
TLL1 -821
ADAMTS8 -795
CAPN1 -697
ADAM17 -560
LAMA1 -510
BMP7 -475
ITGB2 -450
SCUBE3 -369
LOXL3 -356
CD44 -351
DDR1 -347
PCOLCE -288
PLEC -258
EMILIN1 -188
COL25A1 -69
EMILIN2 -15
PTPRS -2
MMP3 0
ITGB3 84
DMP1 205
PSEN1 218
ICAM3 256
COL6A5 261
COL26A1 316
VCAN 365
ADAM12 403
LOXL2 449
NID2 465
NCAM1 638
COL3A1 796
JAM2 799
COMP 1207
CAPN3 1332
COL2A1 1379
NRXN1 1493
CAPN10 1512
PLOD3 1518
LAMC2 1685
CASP3 1797
ITGA5 1836
BMP1 1861
BMP2 1904
SPP1 2012
DCN 2166
PLOD1 2223
LAMA3 2475
COL12A1 2489
COL18A1 2506
COLGALT2 2670
COL4A3 2673
SPOCK3 2697
FBN2 2827
ITGAM 2965
COL19A1 2994
CAPNS1 3023
SDC3 3088
FMOD 3111
MMP14 3217
PHYKPL 3357
P4HA1 3766
MMP15 3832
PXDN 3854
COL4A1 3956
COL6A6 4006
FBN3 4021
SERPINH1 4025
SDC4 4216
BCAN 4254
CTSB 4265
COLGALT1 4415
ITGAE 4511
MMP25 4596
ICAM2 4651
CRTAP 4672
CD151 4687
JAM3 4700
VCAM1 4795
PRKCA 4876
LAMB1 5074
COL6A1 5298
SERPINE1 5533
MFAP4 5690
COL10A1 5848
ITGAV 5900
ITGA8 5984
CTSL 6187
SDC2 6188
DAG1 6247
COL6A2 6308
ITGA4 6368
ICAM4 6428
FGF2 6490
TTR 6572
CTSS 6756
ADAM8 6773
EFEMP1 6821
COL1A2 6930
FBLN5 6953
BSG 7084
AGRN 7105
ACTN1 7292
CEACAM1 7298
MMP10 7544
MATN3 7559
ITGA6 7643
IBSP 7651
TGFB3 7970
CAPN15 8076
A2M 8290
ADAM10 8404
MMP7 8544
PPIB 8604
COL21A1 8959
FGA 9219
ITGB7 9305
CTSK 9490


REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
214
set REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT
setSize 21
pANOVA 0.000748
s.dist -0.425
p.adjustANOVA 0.102



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -11633.0
FCN2 -11559.0
C4A -10879.5
C4B -10879.5
CRP -10819.0
MASP1 -10383.0
FCN3 -10157.0
C1QB -10126.0
CFD -9361.0
MBL2 -9077.0
C3 -5985.0
C1S -5493.0
COLEC10 -5455.0
COLEC11 -5126.0
CFB -4429.0
MASP2 -3170.0
C2 -2040.0
C1QC 1879.0
C1R 3059.0
GZMM 3253.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -11633.0
FCN2 -11559.0
C4A -10879.5
C4B -10879.5
CRP -10819.0
MASP1 -10383.0
FCN3 -10157.0
C1QB -10126.0
CFD -9361.0
MBL2 -9077.0
C3 -5985.0
C1S -5493.0
COLEC10 -5455.0
COLEC11 -5126.0
CFB -4429.0
MASP2 -3170.0
C2 -2040.0
C1QC 1879.0
C1R 3059.0
GZMM 3253.0
C1QA 6057.0


REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
1585
set REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
setSize 679
pANOVA 0.000971
s.dist 0.0742
p.adjustANOVA 0.117



Top enriched genes

Top 20 genes
GeneID Gene Rank
POTEE 9819
GMIP 9541
ARHGAP11B 9522
ZNF512B 9266
RND1 9170
H3C1 9085
STBD1 9077
YKT6 9072
H2AZ2 8952
ARHGAP11A 8905
GRB7 8889
MYL6 8862
DDX39B 8852
GOPC 8827
TUBA3C 8794
SCAI 8780
ABCD3 8770
MAPRE1 8713
KNTC1 8636
TUBB1 8617

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
POTEE 9819.0
GMIP 9541.0
ARHGAP11B 9522.0
ZNF512B 9266.0
RND1 9170.0
H3C1 9085.0
STBD1 9077.0
YKT6 9072.0
H2AZ2 8952.0
ARHGAP11A 8905.0
GRB7 8889.0
MYL6 8862.0
DDX39B 8852.0
GOPC 8827.0
TUBA3C 8794.0
SCAI 8780.0
ABCD3 8770.0
MAPRE1 8713.0
KNTC1 8636.0
TUBB1 8617.0
H2BC17 8591.0
H4C12 8556.0
FAM83B 8475.0
PPP1R14A 8437.0
S100A9 8281.0
PPP2R5D 8269.0
H4C5 8212.0
NET1 8193.0
CLIP1 8150.0
CLASP2 8135.0
ARHGEF5 8123.0
LEMD3 8027.0
ARHGAP1 8022.0
PPP2R5B 7999.0
ANKFY1 7993.0
KCTD13 7979.0
RHOB 7922.0
CDC42EP5 7893.0
MSI2 7882.0
TAOK1 7879.0
RND2 7871.0
SCFD1 7869.0
DBN1 7841.0
CENPO 7809.0
BAIAP2L2 7793.0
PARD6B 7763.0
MAD1L1 7744.0
PPP2R1B 7726.0
RPS27 7711.0
FRS2 7697.0
LMAN1 7663.0
TPM3 7658.0
MAPK14 7626.0
CDC37 7555.0
CTTN 7494.0
SOS2 7471.0
PDPK1 7458.0
NCKIPSD 7406.0
WDR81 7349.0
H2BC9 7299.5
H3C7 7299.5
ACTN1 7292.0
RHOV 7289.0
B9D2 7287.0
LIMK2 7205.0
CKAP4 7080.0
DOCK9 7072.0
SEH1L 7023.0
ALS2 6994.0
TAX1BP3 6990.0
FILIP1 6958.0
UBXN11 6909.0
ADD3 6903.0
FAM169A 6868.0
SRGAP2 6853.0
DOCK8 6826.0
ERBIN 6825.0
ARHGAP12 6806.0
ITSN2 6805.0
EVL 6783.0
MCF2L 6750.0
STAM2 6747.0
DYNC1LI1 6729.0
DYNC1H1 6601.0
ARPC1A 6552.0
SPC24 6531.0
AURKB 6511.0
RHOQ 6464.0
ABI2 6438.0
CENPF 6418.0
RHOD 6391.0
INCENP 6349.0
PRKCZ 6322.0
RAB7A 6317.0
CCT6A 6234.0
LAMTOR1 6216.0
WASF1 6194.0
ARHGAP44 6163.0
WWP2 6139.0
ARAP1 6062.0
ABR 6051.0
H4C3 6009.0
ARFGAP3 5940.0
ARHGEF3 5925.0
NDEL1 5866.0
H2BC12 5854.0
GOLGA3 5847.0
ALDH3A2 5808.0
DIAPH3 5748.0
PPP2R5A 5717.0
CDC42EP2 5702.0
SAMM50 5685.0
H2AC4 5676.0
SLITRK3 5624.0
H2AC20 5583.0
AMIGO2 5578.0
TUBA4A 5555.0
H3C8 5547.0
RAP1GDS1 5454.0
VAV2 5432.0
MAPK11 5430.0
DDRGK1 5361.0
NOXA1 5340.0
H4C9 5306.0
FGD3 5291.0
PIK3CA 5267.0
RAC3 5256.0
STK10 5241.0
FLOT1 5117.0
CDC42BPB 5091.0
CLTC 5050.0
PRKCB 4990.0
DSG2 4938.0
PRKCA 4876.0
SOS1 4874.0
DOCK7 4860.0
PIK3R1 4837.0
FGD2 4827.0
ARL13B 4810.0
NUP98 4773.0
CENPE 4766.0
NCKAP1 4739.0
PLEKHG1 4731.0
H4C6 4702.0
PAK2 4670.0
YWHAZ 4640.0
TRAK1 4620.0
PLEKHG3 4597.0
PARD6A 4581.5
ARPC3 4577.0
NIPSNAP2 4567.0
ANKRD26 4546.0
WIPF2 4509.0
PPP2R5C 4507.0
CDC42 4492.0
ARHGAP33 4477.0
KIF2C 4469.0
KIDINS220 4454.0
BRK1 4435.0
ABI1 4400.0
KNL1 4393.0
KLC3 4365.0
ROCK2 4363.0
KTN1 4356.0
NUP160 4345.0
DOCK2 4342.0
SLC4A7 4337.0
ABL2 4332.0
RTKN 4322.0
PIK3R2 4257.0
SPEN 4241.0
KIF18A 4221.0
TWF1 4211.0
TAOK3 4209.0
ARHGEF7 4193.0
MYO9A 4171.0
H3-3A 4158.0
PRAG1 4145.0
CHN1 4140.0
CTNNB1 4100.0
H2BC13 4070.0
PEAK1 4056.0
WDR11 4027.0
NISCH 4026.0
NDE1 4024.0
FRS3 3993.0
DIAPH1 3961.0
TMEM59 3937.0
NUF2 3895.0
ABL1 3849.0
H2AC7 3829.5
H2BC7 3829.5
PRC1 3826.0
TUBB8 3806.0
PREX2 3744.0
GNA13 3741.0
CENPK 3678.0
H2BC6 3659.0
SWAP70 3534.0
TUBB4A 3526.0
TUBA4B 3468.0
CENPN 3409.0
CKAP5 3390.0
ARHGEF2 3381.0
RCC2 3360.0
TUBB4B 3352.0
AKAP12 3322.0
PPP1R12B 3314.0
CYFIP2 3311.0
FAM91A1 3308.0
KDM1A 3304.0
RHOH 3252.0
MYL12B 3166.0
BIRC5 3110.0
H2AC18 3107.5
H2AC19 3107.5
BUB1B 3099.0
FMNL3 3079.0
ROPN1 3056.0
DYNC1I2 3054.0
NUP37 3040.0
VAPB 2963.0
ARHGAP30 2859.0
H4C16 2844.0
ARHGEF40 2805.0
FAF2 2786.0
VAV3 2778.0
DOCK10 2768.0
BUB3 2757.0
BCR 2602.0
DVL1 2494.0
RHOBTB3 2462.0
TNFAIP1 2445.0
ZAP70 2429.0
KLC1 2423.0
PAK6 2421.0
TEX2 2410.0
HMOX2 2392.0
CSK 2358.0
ARAP2 2351.0
ARPC5 2343.0
CENPU 2336.0
H4C1 2332.0
SH3BP1 2323.0
KIF14 2321.0
STK38 2320.0
DVL3 2296.0
SGO2 2287.0
H3C11 2270.0
IQGAP1 2259.0
ANKLE2 2243.0
RHOT1 2161.0
SRRM1 2116.0
FAM135A 2104.0
ARHGAP42 2066.0
H2AJ 2047.0
NCK2 2036.0
COPS4 2031.0
CAVIN1 2014.0
CTNNA1 2009.0
PKN3 1956.0
SEC13 1952.0
SNAP23 1931.0
H3C6 1887.0
SPTBN1 1819.0
PPP2CA 1817.0
TIAM2 1816.0
VANGL1 1758.0
CENPA 1710.0
ARHGAP25 1678.0
DDX4 1670.0
ARHGAP18 1638.0
PRKCD 1634.0
SHKBP1 1630.0
DVL2 1626.0
SENP1 1573.0
ITSN1 1540.0
HSP90AB1 1539.0
WDR91 1494.0
NUP107 1476.0
PFN2 1443.0
LMNB1 1405.0
NSFL1C 1371.0
H2BC4 1347.0
RND3 1338.0
GRB2 1328.0
RHOBTB2 1322.0
KDM4C 1298.0
HGS 1269.0
LETM1 1226.0
CENPH 1223.0
H3C2 1183.0
NCKAP1L 1154.0
TRAK2 1117.0
CLASP1 1102.0
MAD2L1 1096.0
ARHGEF26 1090.0
IQGAP2 1060.0
ARHGAP35 1054.0
TUBB3 1052.0
LCK 1044.0
NDUFA5 1001.0
ARHGDIB 953.0
H2AC6 949.0
CIT 929.0
SLITRK5 926.0
ARHGAP45 895.0
MAPK3 866.0
PTK2B 854.0
VHL 843.0
ARHGAP8 842.0
MYH11 837.0
PLXNA1 830.0
BUB1 812.0
STARD13 809.0
FAM13A 746.0
CDC25C 737.0
H2BC21 723.0
MPP7 709.0
PKP4 553.0
SRC 550.0
VANGL2 513.0
AHCTF1 452.0
GFOD1 424.0
CAPZB 419.0
MRTFA 400.0
CCDC115 369.0
ARHGAP5 333.0
GJA1 312.0
YWHAG 201.0
ARHGEF10 178.0
STIP1 143.0
VRK2 129.0
CUL3 113.0
PKN2 94.0
ARHGEF18 12.0
H2BC5 -9.0
ARHGAP19 -23.0
CENPT -26.0
ARHGAP17 -53.0
TOR1AIP1 -75.0
DAAM1 -95.0
ARHGAP28 -99.0
RAC2 -151.0
SEMA4F -174.0
BLTP3B -289.0
SYDE1 -296.0
EPSTI1 -303.0
RASGRF2 -343.0
H3C4 -374.0
PPP1CB -384.0
DYNC1I1 -433.0
PCDH7 -477.0
DSP -542.0
TUBB2B -595.0
MYO9B -643.0
OSBPL11 -702.0
STOM -727.0
TMOD3 -767.0
ELMO2 -780.0
FGD5 -858.0
ARHGAP20 -906.0
KIF5B -945.0
PTPN13 -982.0
ZWILCH -1021.0
H2BC10 -1032.0
MAP3K11 -1075.0
RHOT2 -1083.0
MTX1 -1100.0
RANGAP1 -1150.0
AKAP13 -1191.0
PIK3C3 -1205.0
OBSCN -1239.0
CCNE1 -1248.0
CALM1 -1278.0
DNMBP -1294.0
NSL1 -1316.0
PLXND1 -1377.0
DEPDC1B -1387.0
PPP2R1A -1400.0
H2BC15 -1414.0
DEF6 -1442.0
PFN1 -1458.0
DSG1 -1461.0
SH3PXD2A -1462.0
WASL -1503.0
NCOA2 -1529.0
NUDC -1543.0
TIAM1 -1595.0
STMN2 -1648.0
H2AX -1653.0
NDC80 -1672.0
NCF2 -1761.0
RBBP6 -1819.0
PAK1 -1880.0
WHAMM -1904.0
ACTR3 -1930.0
PAK5 -1932.0
RHOJ -1970.0
PLEKHG5 -1982.0
TRA2B -2003.0
IL32 -2026.0
HTR7 -2042.0
ARPC2 -2180.0
PIK3R4 -2201.0
ARHGAP10 -2206.0
ZWINT -2209.0
FARP1 -2224.0
ARHGAP15 -2285.0
GARRE1 -2325.0
MACO1 -2338.0
PAFAH1B1 -2384.0
ECT2 -2476.0
CDCA8 -2485.0
DBT -2502.0
PLEKHG4 -2503.0
LIMK1 -2563.0
FARP2 -2585.0
MIS12 -2586.0
TFRC -2599.0
WASF2 -2615.0
COPS2 -2623.0
YWHAE -2626.0
H4C13 -2630.0
H4C4 -2649.0
ESYT1 -2662.0
NF2 -2664.0
FMNL1 -2681.0
CKB -2696.0
H4C8 -2728.0
TUBA1C -2761.0
ZW10 -2773.0
CDKN1B -2790.0
SHMT2 -2796.0
HINT2 -2797.0
VIM -2800.0
VAV1 -2815.0
CPNE8 -2843.0
DOCK6 -2850.0
CAV1 -2895.0
CHN2 -2950.0
H2BC3 -2958.0
RANBP2 -2965.0
NUP133 -2987.0
GIT2 -3032.0
TUBB6 -3105.0
SPTAN1 -3189.0
ARHGAP26 -3234.0
DYNLL1 -3248.0
RHOG -3249.0
MYH9 -3268.0
NGEF -3288.0
WIPF1 -3304.0
ROCK1 -3317.0
SPATA13 -3338.0
ARHGEF25 -3360.0
BAIAP2L1 -3364.0
RHOC -3370.0
PLD2 -3382.0
NCK1 -3408.0
TXNL1 -3434.0
SPDL1 -3435.0
EMC3 -3447.0
PPP1R12A -3452.0
FLOT2 -3481.0
H4C11 -3485.0
TRIP10 -3515.0
ARHGEF12 -3531.0
ARPC4 -3605.0
MYH10 -3625.0
CDC42EP4 -3643.0
ITGB3BP -3696.0
IQGAP3 -3731.0
SCRIB -3776.0
SRGAP1 -3820.0
PLEKHG4B -3873.0
MAPK1 -3902.0
MFN2 -3922.0
CENPS -3932.0
CFTR -3968.0
TUBA1B -3969.0
CDC42BPA -4038.0
DOCK4 -4040.0
MYO19 -4092.0
ARHGAP22 -4111.0
KLK3 -4180.0
PTK2 -4183.0
PPP2R5E -4190.0
DYNC1LI2 -4243.0
CCT2 -4273.0
CPSF7 -4278.0
TRIO -4284.0
STAM -4324.0
SH3RF1 -4329.0
FERMT2 -4347.0
BAIAP2 -4376.0
MTR -4377.0
PLEKHG2 -4414.0
PDE5A -4417.0
ARHGAP31 -4524.0
FAM13B -4526.0
TJP2 -4570.0
TPM4 -4604.0
NOXO1 -4611.0
CDC42EP1 -4666.0
RHOA -4678.0
RACGAP1 -4730.0
MEN1 -4780.0
CFL1 -4810.0
RHOF -4818.0
PLK1 -4822.0
YWHAQ -4844.0
PLIN3 -5028.0
ARHGAP39 -5037.0
KLC2 -5044.0
ARHGEF11 -5075.0
ACBD5 -5089.0
FGD4 -5103.0
ACTC1 -5125.0
ARHGAP29 -5133.0
DST -5184.0
DOCK1 -5214.0
PAK4 -5225.0
TUBAL3 -5273.0
PICALM -5277.0
YWHAH -5306.0
TUBA1A -5328.0
MYO6 -5355.0
RALBP1 -5380.0
PREX1 -5385.0
CCT7 -5421.0
PKN1 -5454.0
CENPC -5501.0
SKA2 -5511.0
MYL9 -5545.0
CYFIP1 -5596.0
ARHGDIG -5638.0
WASF3 -5670.0
XPO1 -5699.0
SRF -5706.0
FNBP1L -5730.0
DLG4 -5765.0
ARHGAP27 -5779.0
GPS1 -5787.0
SRGAP3 -5794.0
ARHGEF4 -5802.0
WDR6 -5860.0
NOX3 -5930.0
H3C3 -5940.0
ARHGAP23 -6055.0
DLG5 -6070.0
ARHGEF1 -6092.0
ARFGAP2 -6098.0
GIT1 -6177.0
SOWAHC -6246.0
RHPN1 -6333.0
ARHGEF17 -6342.0
CENPL -6355.0
RRAS2 -6359.0
TUBB2A -6393.0
H2BC1 -6416.0
CCDC88A -6442.0
DOCK5 -6453.0
YWHAB -6461.0
CEP97 -6513.0
PIN1 -6552.0
LRRC41 -6589.0
WIPF3 -6615.0
LBR -6626.0
CCP110 -6659.0
LIN7B -6716.0
CYBA -6734.0
H2BC11 -6780.0
SYDE2 -6783.0
KALRN -6808.0
H2BC26 -6814.0
JAG1 -6851.0
SPC25 -6926.0
PLEKHG6 -6943.0
MYH14 -6999.0
FNBP1 -7006.0
H4C2 -7011.0
CENPP -7022.0
PIK3R3 -7035.0
KCTD3 -7043.0
RHPN2 -7061.0
CENPQ -7094.0
KIF2B -7248.0
KIF2A -7265.0
LRRC1 -7275.0
MUC13 -7277.0
UACA -7326.0
VAMP3 -7336.0
KLC4 -7349.0
RNF20 -7365.0
H2AZ1 -7369.0
DYNLL2 -7375.0
MFN1 -7421.0
FMNL2 -7431.0
MCAM -7457.0
ARHGEF28 -7495.0
C1QBP -7502.0
RAPGEF1 -7551.0
DLC1 -7580.0
CPD -7712.0
ARHGAP32 -7730.0
NUP43 -7764.0
DOCK3 -7820.0
RHOU -7881.0
ARHGAP21 -7888.0
PGRMC2 -7909.0
ARHGEF16 -7914.0
H3-3B -7982.0
SGO1 -7992.0
ACTG1 -8054.0
TUBA8 -8057.0
STX5 -8109.0
HSPE1 -8117.0
ARHGAP24 -8203.0
ARHGAP40 -8220.0
SLK -8248.0
ANLN -8270.0
RAC1 -8281.0
CDC42SE2 -8286.0
RASAL2 -8310.0
ARHGEF39 -8347.0
RHOBTB1 -8417.0
HNRNPC -8449.0
PLXNB1 -8605.0
NCF4 -8667.0
ARAP3 -8689.0
H2AC8 -8778.0
TUBA3D -8798.0
KIF5A -8814.0
ARHGAP9 -8820.0
CDC20 -8838.0
BASP1 -8880.0
DSN1 -8883.0
ACTR2 -8931.0
PHIP -9000.0
ITGB1 -9031.0
KLK2 -9056.0
EPHA2 -9069.0
H2BC8 -9079.0
PMF1 -9098.0
RALGAPA1 -9115.0
JUP -9129.0
PLD1 -9471.0
VCP -9546.0
ARHGEF19 -9595.0
CENPM -9662.0
TMEM87A -9692.0
TMPO -9909.0
NDUFS3 -9960.0
H2BC14 -9980.0
ARHGDIA -9984.0
H3C10 -10013.0
H2AC14 -10060.0
HSP90AA1 -10062.0
ARHGEF10L -10326.0
ACTB -10333.0
TUBA3E -10348.0
NUP85 -10353.0
EFHD2 -10360.0
MYLK -10393.0
ARPC1B -10420.0
STEAP3 -10651.0
S100A8 -10656.0
SLC1A5 -10857.0
PPP2CB -10912.0
CDH1 -10913.0
H3C12 -10932.0
AAAS -10980.0
SKA1 -11071.0
CDC42EP3 -11094.0
TAGAP -11239.0
PPP1CC -11311.0
SFN -11352.0
ARHGEF15 -11445.0


REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
1024
set REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize 1356
pANOVA 0.000999
s.dist 0.0533
p.adjustANOVA 0.117



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD52 9716
B4GAT1 9695
ZNF350 9542
SUZ12 9441
GALNT6 9411
AMBN 9390
SATB1 9382
PLET1 9338
CHML 9303
RAB5C 9295
LHB 9274
FGA 9219
VNN1 9212
TGFBR1 9195
GALNT8 9180
BMI1 9147
ASB7 9103
RAB3D 9100
YKT6 9072
RIPK1 8935

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD52 9716.0
B4GAT1 9695.0
ZNF350 9542.0
SUZ12 9441.0
GALNT6 9411.0
AMBN 9390.0
SATB1 9382.0
PLET1 9338.0
CHML 9303.0
RAB5C 9295.0
LHB 9274.0
FGA 9219.0
VNN1 9212.0
TGFBR1 9195.0
GALNT8 9180.0
BMI1 9147.0
ASB7 9103.0
RAB3D 9100.0
YKT6 9072.0
RIPK1 8935.0
SERPIND1 8931.0
TMED10 8927.0
TUBA3C 8794.0
GALNT3 8789.0
PIGS 8764.0
PMM1 8758.0
NEURL2 8750.0
NR1H2 8734.0
RAB12 8696.0
RAB38 8667.0
H2AC17 8661.0
ASB5 8627.0
POMGNT2 8622.0
AXIN2 8621.0
TUBB1 8617.0
LY6G6D 8616.0
H2BC17 8591.0
RAB34 8573.0
H4C12 8556.0
LRR1 8534.0
PSMD13 8524.0
ARF3 8487.0
RNF135 8451.0
ADAM10 8404.0
GCNT7 8385.0
CALU 8362.0
USP33 8337.0
RWDD3 8334.0
DOLPP1 8333.0
GOSR1 8266.0
PROZ 8246.0
MUC20 8240.0
CNTN3 8236.0
RNF146 8213.0
H4C5 8212.0
DNMT3B 8185.0
SEC22C 8176.0
SLC17A5 8168.0
FBXW9 8165.0
RAB33B 8148.0
FPGT 8141.0
NSF 8127.0
RAB42 8119.0
UMOD 8118.0
IGFBP3 8092.0
CREBBP 8084.0
FGF23 8075.0
LY6E 8067.0
ARF4 8059.0
NEU2 8025.0
SMURF2 8023.0
RAD18 8019.0
ARSG 7986.0
SEC24B 7983.0
KLHL2 7955.0
TRAF6 7953.0
TEX101 7936.0
NFRKB 7929.0
ST3GAL1 7926.0
NUP54 7883.0
SCFD1 7869.0
TTLL12 7838.0
COG1 7812.0
COPS8 7785.0
NRN1L 7775.0
TOP1 7768.0
AMFR 7762.0
HDAC4 7743.0
PSMF1 7714.0
DCAF7 7700.0
COMMD3 7671.0
ACTR8 7667.0
LMAN1 7663.0
RBX1 7648.0
FBXW4 7640.0
UBE2Q2 7606.0
CBX5 7575.0
MATN3 7559.0
EIF5A2 7548.0
COPS3 7514.0
UBE2J2 7481.0
BABAM1 7457.0
DCTN4 7449.0
RAB18 7432.0
PEX12 7414.0
BGLAP 7413.0
RFT1 7361.0
RAB19 7329.0
HERC2 7326.0
HDAC1 7322.0
PUM2 7317.0
CDK1 7310.0
PSMD11 7309.0
FBXL5 7304.0
H2BC9 7299.5
LARGE2 7261.0
FOXK1 7245.0
RPA1 7231.0
DCAF4 7184.0
SCG2 7173.0
TPR 7143.0
MAN2A2 7117.0
CDC34 7102.0
FOXL2 7095.0
APOB 7093.0
CKAP4 7080.0
ATXN3 7075.0
COPS6 7073.0
POFUT2 7067.0
MUCL1 7044.0
SEH1L 7023.0
GALNT5 7008.0
YOD1 6974.0
RAB21 6970.0
ALG10B 6965.0
PLAUR 6961.0
ADAMTS10 6950.0
PPARG 6934.0
PSME4 6905.0
USP16 6904.0
PSMA2 6867.0
KAT2A 6840.0
B4GALT4 6766.0
STAM2 6747.0
OTUD3 6737.0
NEU4 6736.0
SPP2 6734.0
DYNC1LI1 6729.0
PDIA6 6715.0
MBTPS1 6707.0
FBXW8 6705.0
UBA2 6702.0
USP8 6699.0
PSMC6 6685.0
SUDS3 6676.0
FBXL4 6668.0
GOLGB1 6655.0
QSOX1 6652.0
NPLOC4 6638.0
CTR9 6622.0
TNKS 6617.0
FBXO41 6605.0
DYNC1H1 6601.0
PARP1 6591.0
RAB40B 6589.0
CLSPN 6574.0
RAB40C 6571.0
COG5 6565.0
MPI 6557.0
ALG11 6555.0
C1GALT1 6549.0
CTSA 6514.0
AURKB 6511.0
MAN2A1 6510.0
WDTC1 6498.0
ALG9 6455.0
IFIH1 6444.0
FBXO44 6425.0
PTP4A2 6423.0
PGM3 6420.0
TFAP2A 6366.0
OTUB2 6363.0
INCENP 6349.0
TGFBR2 6348.0
PREB 6333.0
RAB7A 6317.0
MVD 6309.0
CBX2 6305.0
UFD1 6292.0
PSMB6 6285.0
SEC23IP 6283.0
TRIM13 6280.0
ALG12 6257.0
APOL1 6255.0
DAG1 6247.0
FUCA1 6244.0
MLEC 6239.0
SDC2 6188.0
MAVS 6186.0
CANX 6158.0
USP15 6151.0
PIGB 6150.0
FBXO2 6140.0
MGAT4B 6137.0
TRRAP 6116.0
GANAB 6098.0
AFP 6085.0
DPP3 6084.0
NOD1 6079.0
CUL7 6075.0
USP22 6064.0
TPST2 6060.0
KLHL20 6056.0
COMMD6 6026.0
H4C3 6009.0
CMAS 5993.0
UBE2V2 5978.0
NUCB1 5964.0
UBE2T 5947.0
ARFGAP3 5940.0
IL33 5933.0
NR4A2 5917.0
USP44 5862.0
H2BC12 5854.0
APLP2 5842.0
KBTBD6 5815.0
UCHL5 5797.0
RIPK2 5784.0
PIGN 5764.0
TNIP3 5762.0
NRN1 5740.0
TFAP2B 5723.0
TRAPPC2L 5721.0
PPARGC1A 5699.0
COG2 5682.0
H2AC4 5676.0
SPARCL1 5671.0
TULP4 5633.0
COMMD7 5630.0
ST3GAL2 5586.0
H2AC20 5583.0
NUP93 5581.0
TUBA4A 5555.0
ST8SIA6 5552.0
ST8SIA5 5545.0
APOA5 5537.0
PPARA 5527.0
AMDHD2 5520.0
KCTD6 5517.0
CTSC 5493.0
KLHL21 5484.0
INO80 5468.0
NEU1 5466.0
PSMD9 5439.0
XPC 5431.0
MDM4 5418.0
USP42 5408.0
NRIP1 5403.0
DCUN1D3 5389.0
ZRANB1 5383.0
USP4 5372.0
UCHL1 5365.0
MGAT4A 5359.0
ESR1 5343.0
ST6GAL1 5307.0
H4C9 5306.0
BABAM2 5265.0
CCNA2 5259.0
WDR5 5255.0
RAB8A 5236.0
MPDU1 5191.0
UBE2H 5128.0
RAB43 5123.0
NTNG2 5104.0
DPM3 5099.0
GALNT1 5098.0
SHPRH 5087.0
EEF1AKMT2 5084.0
GALNT2 5080.0
LAMB1 5074.0
PSMD7 5071.0
PIAS1 5064.0
FBXW5 5022.0
USP28 5019.0
SOCS2 5008.0
SUMO2 5002.0
CNTN5 4993.0
CTBP1 4983.0
IGFBP1 4974.0
PIGZ 4966.0
THBS2 4958.0
RAB23 4934.0
PSMB3 4905.0
PSMB7 4896.0
FBXL22 4881.0
LYPD3 4875.0
USP21 4866.0
NICN1 4841.0
SIAH2 4839.0
PHC3 4830.0
HLTF 4817.0
KBTBD7 4816.0
UBE2E3 4814.0
FBXW2 4813.0
DCAF10 4811.0
SENP5 4796.0
NUP98 4773.0
SEMA5A 4760.0
OS9 4742.0
NUP35 4738.0
ICMT 4736.0
FBXL12 4726.0
EID3 4723.0
ABRAXAS2 4718.0
H4C6 4702.0
NDC1 4699.0
FKBP8 4676.0
USP30 4671.0
WDR20 4666.0
ASXL2 4659.0
NUP210 4646.0
TUSC3 4605.0
UBE2W 4575.0
APOE 4556.0
WDR48 4502.0
CCN1 4497.0
MAN1C1 4489.0
ADAMTSL4 4468.0
SEC16B 4447.0
PENK 4420.0
MDC1 4416.0
PIAS4 4387.0
COG7 4361.0
KTN1 4356.0
NUP160 4345.0
ASB4 4334.0
UBE2K 4328.0
CSNK1D 4310.0
FBXO30 4298.0
UBE2I 4284.0
RAB36 4280.0
SUMF2 4278.0
TPGS1 4272.0
LMAN2L 4267.0
RAB35 4246.0
ATXN7 4231.0
GNPNAT1 4225.0
ALG6 4201.0
PIGM 4197.0
DTL 4151.0
COMMD9 4141.0
TGOLN2 4130.0
PIGG 4115.0
KLHL9 4097.0
RNF168 4092.0
RARA 4076.0
L3MBTL2 4072.0
H2BC13 4070.0
ARSJ 4067.0
COPB2 4052.0
TPGS2 4050.0
EDEM3 4046.0
PSMB1 4033.0
PCNA 4020.0
TADA2B 4019.0
PSMA5 4001.0
GALNTL6 3951.0
RAB39A 3889.0
CUL4A 3860.0
MARCHF6 3851.0
PSMD14 3838.0
CDKN1A 3835.0
H2AC7 3829.5
H2BC7 3829.5
SRD5A3 3820.0
TUBB8 3806.0
PEX13 3772.0
RNF144A 3761.0
B3GNT2 3756.0
CUL1 3754.0
RAB5B 3739.0
PIGY 3735.0
RAB4A 3724.0
SCMH1 3707.0
TP53BP1 3700.0
CUL2 3699.0
PIAS2 3666.0
H2BC6 3659.0
RAB29 3646.0
SMAD2 3580.0
HDAC2 3563.0
VASH1 3542.0
TUBB4A 3526.0
DCAF17 3510.0
ARRB1 3508.0
SMAD1 3494.0
RNF5 3485.0
TFAP2C 3482.0
DNMT3A 3470.0
PALB2 3469.0
TUBA4B 3468.0
UBE2F 3463.0
NUP214 3453.0
TRAPPC6B 3451.0
EEF2KMT 3444.0
CDH2 3440.0
SUMO3 3428.0
AREG 3387.0
TUBB4B 3352.0
COPB1 3327.0
ARFGAP1 3310.0
ST3GAL3 3301.0
DDB1 3298.0
UHRF2 3294.0
NANP 3275.0
PIGX 3270.0
COMMD4 3254.0
EDEM1 3249.0
SVBP 3239.0
ADAMTS19 3232.0
KLHL22 3214.0
CDC73 3203.0
CDC25A 3199.0
MTA1 3198.0
RUVBL1 3185.0
GAN 3179.0
FBXL16 3139.0
FUCA2 3138.0
TTLL4 3135.0
BIRC5 3110.0
H2AC18 3107.5
H2AC19 3107.5
APOA2 3105.0
NSMCE3 3100.0
VCPIP1 3089.0
ANK1 3085.0
DYNC1I2 3054.0
NUP37 3040.0
PSMD12 3007.0
VCPKMT 3005.0
DCUN1D2 2996.0
MCRS1 2987.0
LMAN2 2972.0
BIRC3 2918.0
FBXL20 2900.0
NAPB 2897.0
ENGASE 2893.0
PIGF 2877.0
H4C16 2844.0
DNAJC3 2833.0
ST3GAL4 2829.0
DAD1 2828.0
NUS1 2823.0
B4GALNT2 2822.0
PIGO 2816.0
MGAT4C 2802.0
NR5A2 2788.0
PRKN 2779.0
DCTN3 2734.0
VNN2 2695.0
SAR1B 2664.0
COMMD1 2631.0
TBC1D20 2619.0
PSMA4 2616.0
USP25 2614.0
SUMF1 2569.0
MUC6 2554.0
PSME1 2536.0
SEC22A 2535.0
PPP6R1 2517.0
HDAC7 2503.0
USP13 2456.0
CBX4 2447.0
VDAC1 2375.0
OTULIN 2368.0
WFS1 2366.0
MUC4 2352.0
H4C1 2332.0
PML 2311.0
BTRC 2310.0
PIGV 2302.0
KLHL3 2282.0
RABGGTA 2269.0
DCAF11 2268.0
COPZ1 2263.0
TRAPPC9 2260.0
TRIM27 2257.0
MCFD2 2251.0
FBXO21 2238.0
ALG14 2235.0
PGAP1 2224.0
MAT2B 2218.0
ADAMTS17 2198.0
METTL22 2186.0
DCAF5 2179.0
NPL 2174.0
RHOT1 2161.0
PPP6R3 2150.0
RAE1 2123.0
HNRNPK 2120.0
RAB20 2103.0
STAMBPL1 2082.0
NUP188 2071.0
BIRC2 2041.0
COPS4 2031.0
GBF1 2030.0
UGGT1 2022.0
NOD2 2013.0
SPP1 2012.0
GPAA1 1989.0
GNE 1986.0
RAD23B 1983.0
MITF 1977.0
SENP2 1955.0
SEC13 1952.0
CHD3 1941.0
IGFBP4 1940.0
SMAD4 1939.0
NEGR1 1925.0
DCUN1D1 1885.0
F10 1882.0
PRSS23 1878.0
GORASP1 1857.0
INO80D 1853.0
ZBTB16 1847.0
MEPE 1846.0
RPS27A 1837.0
TDG 1826.0
SPTBN1 1819.0
NCOR2 1788.0
GALNT7 1774.0
USP14 1770.0
SLC35C1 1749.0
KLHL11 1742.0
FBXL8 1733.0
RAB5A 1717.0
RNF2 1715.0
CYLD 1689.0
DPM2 1684.0
FAM20A 1653.0
DOHH 1640.0
PIGK 1575.0
SENP1 1573.0
DPH5 1560.0
KDM1B 1558.0
TOMM70 1537.0
KEAP1 1532.0
NUP155 1514.0
TAB1 1505.0
NUP107 1476.0
CCDC8 1458.0
VWA1 1444.0
FBXO17 1427.0
TTLL8 1412.0
H2BC4 1347.0
TOP2A 1336.0
COG3 1330.0
FCSK 1327.0
MANEA 1326.0
GALNT13 1324.0
RAB1B 1299.0
HGS 1269.0
USP20 1260.0
SQSTM1 1240.0
RXRA 1224.0
GATA3 1188.0
ALG5 1187.0
RCN1 1181.0
BRCA1 1137.0
RAB4B 1130.0
ADRB2 1122.0
ST6GALNAC1 1106.0
ADAMTS12 1104.0
TRAF2 1082.0
ART3 1079.0
SBSPON 1070.0
MXRA8 1055.0
TUBB3 1052.0
TRAPPC6A 1046.0
COMMD8 1033.0
GPLD1 1030.0
COPS7A 992.0
PIAS3 983.0
DCAF6 981.0
ASB14 968.0
H2AC6 949.0
USP12 935.0
CD109 925.0
PSMD1 886.0
B3GNTL1 853.0
VHL 843.0
SEC16A 838.0
ARSB 808.0
GGCX 757.0
RNF123 749.0
COP1 725.0
H2BC21 723.0
DDOST 699.0
STC2 694.0
FBXO11 692.0
TOPORS 689.0
USP47 674.0
B4GALT5 667.0
ST8SIA3 666.0
F5 663.0
TTLL5 655.0
LY6G6C 633.0
NUP205 632.0
RAB8B 631.0
RAET1G 627.0
LYPD1 602.0
RAB13 591.0
PSMD6 572.0
PSMC3 570.0
PSMB2 533.0
USP3 532.0
GALNT10 496.0
CUL5 463.0
PSMD8 460.0
PNPLA2 425.0
CAPZB 419.0
DNAJC24 407.0
MRTFA 400.0
FBXO31 392.0
VCAN 365.0
COPA 358.0
H2AC11 355.0
PSMA3 337.0
H2AC12 334.0
PHC1 323.0
PRMT3 307.0
GALNT4 294.0
STAG1 281.0
KDELR3 266.0
THSD7A 257.0
PEX14 231.0
RRAGA 215.0
FBXL13 213.0
DMP1 205.0
FBXL18 176.0
PSMD5 170.0
UBE2D1 159.0
CUL3 113.0
ACTR10 106.0
NR2C1 104.0
PEX2 89.0
MAN1B1 80.0
DHPS 78.0
NEDD8 47.0
COPG1 38.0
CCNF 32.0
EP300 15.0
FBXO10 -8.0
H2BC5 -9.0
SIN3A -19.0
THRA -89.0
ALB -102.0
SKP2 -107.0
FBXO22 -157.0
KLHL42 -167.0
POMGNT1 -197.0
DPAGT1 -208.0
BTBD6 -246.0
RAB15 -247.0
OPCML -259.0
PMM2 -265.0
SPSB3 -271.0
UBXN7 -279.0
SNX3 -291.0
DPM1 -293.0
ADAMTSL5 -312.0
SPTBN4 -377.0
H2AC13 -397.0
RAB37 -400.0
ETFB -414.0
SOCS5 -427.0
DYNC1I1 -433.0
COG4 -449.0
TMEM115 -493.0
RAB32 -507.0
YY1 -511.0
SEM1 -525.0
DPH6 -527.0
BET1 -547.0
NR5A1 -557.0
MAP3K7 -559.0
TUBB2B -595.0
LMO7 -599.0
ANK3 -618.0
FBXO9 -621.0
ARCN1 -649.0
CISH -679.0
DCUN1D5 -745.0
EPAS1 -750.0
FBXO6 -766.0
SMAD7 -785.0
ADAMTS8 -795.0
PSMA1 -810.0
TTLL1 -824.0
ASB3 -833.0
HIPK2 -843.0
IDE -847.0
FBXO32 -874.0
CD59 -901.0
USP34 -951.0
ADAMTSL1 -955.0
FUT8 -959.0
DHDDS -962.0
RTN4RL1 -972.0
TRIM4 -1009.0
FN1 -1014.0
DCAF16 -1028.0
H2BC10 -1032.0
MIA2 -1050.0
SAFB -1061.0
POLB -1123.0
RAB1A -1135.0
PIGL -1142.0
RANGAP1 -1150.0
TFG -1151.0
DPH7 -1163.0
ANKRD28 -1170.0
INS -1171.0
TRAF3 -1175.0
DPH2 -1176.0
GALNT16 -1201.0
TTLL9 -1219.0
UBA6 -1222.0
NUB1 -1251.0
CALM1 -1278.0
EEF1AKMT1 -1302.0
NUDT14 -1341.0
ASGR1 -1357.0
ABRAXAS1 -1380.0
H2AC21 -1383.0
RNF185 -1398.0
CNIH2 -1401.0
FN3KRP -1402.0
H2BC15 -1414.0
SENP8 -1431.0
KCTD7 -1455.0
PIGQ -1472.0
FURIN -1473.0
MIA3 -1477.0
SAE1 -1482.0
MUL1 -1486.0
NCOA2 -1529.0
PCGF2 -1542.0
MDM2 -1544.0
ARRB2 -1550.0
SPTBN2 -1563.0
ANK2 -1566.0
MGAT3 -1568.0
FBXO4 -1583.0
SEL1L -1588.0
APC -1598.0
RNF103 -1603.0
RAB11A -1609.0
CBX8 -1633.0
SATB2 -1663.0
TECTB -1668.0
UBE2G2 -1669.0
RAB10 -1682.0
SELENOS -1730.0
SPTB -1735.0
RING1 -1753.0
UBE2D2 -1754.0
SOCS3 -1804.0
NSMCE2 -1806.0
COPS5 -1814.0
MBD5 -1867.0
FOXK2 -1893.0
MELTF -1897.0
CTSZ -1929.0
UBE2M -1931.0
SKIC8 -1944.0
ADAMTS16 -1949.0
BMP4 -1955.0
RAD52 -1965.0
UGGT2 -1983.0
PCSK9 -1992.0
SMC6 -2043.0
DCTN2 -2057.0
AURKA -2075.0
GALNT12 -2084.0
USP10 -2148.0
CHGB -2151.0
PIGU -2184.0
PSME2 -2199.0
TADA3 -2200.0
USP49 -2233.0
XRCC4 -2238.0
TRIM25 -2264.0
ACTL6A -2279.0
DCTN5 -2292.0
MUC5B -2311.0
NTNG1 -2335.0
GLB1 -2342.0
DDB2 -2351.0
TAF10 -2376.0
ASB15 -2389.0
MAN1A2 -2401.0
FBXO15 -2403.0
PSMD4 -2411.0
RNF152 -2418.0
PARK7 -2427.0
ST6GAL2 -2432.0
RORA -2435.0
TRAPPC3 -2437.0
GALNT11 -2452.0
VDAC3 -2460.0
ST6GALNAC5 -2463.0
CDCA8 -2485.0
STT3A -2493.0
MBD6 -2555.0
H2AC15 -2567.0
SEC24D -2584.0
PRSS41 -2597.0
GCNT4 -2598.0
ACTR5 -2607.0
RAB11B -2613.0
COPS2 -2623.0
H4C13 -2630.0
H4C4 -2649.0
PHC2 -2666.0
OTUD7B -2670.0
COPG2 -2679.0
MDGA2 -2702.0
H4C8 -2728.0
FBXL7 -2746.0
TUBA1C -2761.0
HLA-A -2765.0
B3GNT8 -2771.0
KAT2B -2785.0
ADAMTS6 -2812.0
ADAMTS20 -2840.0
TTLL13 -2861.0
BTBD1 -2865.0
RAB2A -2866.0
CNTN4 -2884.0
UCHL3 -2886.0
RABGGTB -2889.0
MGAT5 -2891.0
ETFBKMT -2892.0
RCE1 -2901.0
PROS1 -2904.0
NAPA -2912.0
AGBL1 -2916.0
UBE2G1 -2932.0
FBXW11 -2934.0
KNG1 -2955.0
H2BC3 -2958.0
RANBP2 -2965.0
NUP133 -2987.0
CAND1 -3000.0
COPZ2 -3014.0
TNC -3034.0
FBXW12 -3055.0
APP -3074.0
STX17 -3083.0
DPH1 -3085.0
POMT2 -3093.0
TUBB6 -3105.0
EEF2 -3111.0
LARGE1 -3130.0
NAPG -3141.0
HSP90B1 -3159.0
B3GNT4 -3164.0
RECK -3169.0
SPTAN1 -3189.0
NOP58 -3224.0
BAP1 -3235.0
ELOC -3244.0
DYNLL1 -3248.0
NSMCE1 -3303.0
RAB3C -3328.0
NR1I2 -3341.0
POMT1 -3352.0
ADAMTS5 -3373.0
LY6K -3386.0
ULBP2 -3419.0
EEF1A1 -3420.0
B3GALNT2 -3449.0
UBE2E1 -3458.0
H4C11 -3485.0
UAP1 -3488.0
TNKS2 -3536.0
FBXO27 -3554.0
HIC1 -3557.0
BST1 -3566.0
FN3K -3586.0
GFUS -3602.0
BECN1 -3611.0
HIF1A -3630.0
VDAC2 -3672.0
RAB30 -3674.0
SMAD3 -3680.0
ADAMTS9 -3685.0
CDKN2A -3687.0
TRAPPC10 -3706.0
KLHL5 -3728.0
NR3C2 -3735.0
NR3C1 -3781.0
SEMA5B -3788.0
RAB44 -3823.0
ST6GALNAC4 -3828.0
DERL2 -3839.0
TOMM20 -3842.0
JOSD2 -3843.0
GMDS -3854.0
MGAT2 -3855.5
GCNT3 -3877.0
RAB6A -3882.0
ST3GAL5 -3893.0
RNF139 -3900.0
FBXO7 -3923.0
PEX5 -3925.0
GMPPA -3927.0
ANKRD9 -3958.0
CFTR -3968.0
TUBA1B -3969.0
FGG -3975.0
CAPZA1 -3984.0
NUP50 -3986.0
ALPI -3989.0
CHST4 -4025.0
KDELR2 -4026.0
LEO1 -4029.0
ITIH2 -4051.0
CAMKMT -4076.0
VASH2 -4080.0
SPTBN5 -4125.0
TMEM132A -4144.0
RAB17 -4147.0
MUC7 -4178.0
B3GNT9 -4179.0
TMED7 -4191.0
FBXW7 -4192.0
DYNC1LI2 -4243.0
TGFB1 -4255.0
IGFBP5 -4272.0
SLC35A1 -4302.0
ASB18 -4321.0
STAM -4324.0
GP2 -4340.0
PSMB5 -4359.0
SPON1 -4372.0
GMPPB -4378.0
KLHL25 -4421.0
EVA1A -4425.0
GOSR2 -4473.0
BPIFB2 -4519.0
B4GALT6 -4578.0
SERPINC1 -4591.0
ADAMTS15 -4598.0
PIGH -4624.0
MDGA1 -4631.0
BLM -4634.0
AGTPBP1 -4641.0
SOCS6 -4647.0
MYC -4660.0
RHOA -4678.0
NCOA1 -4726.0
THRB -4734.0
BARD1 -4746.0
CNIH1 -4749.0
NTM -4754.0
CSF1 -4755.0
STAMBP -4770.0
DCTN6 -4777.0
MEN1 -4780.0
PSMD3 -4790.0
PSMD2 -4823.0
TECTA -4852.0
SEC22B -4858.0
CD55 -4870.0
COPS7B -4892.0
RAB2B -4936.0
WSB1 -4947.0
USP48 -4948.0
PSMA7 -4955.0
INO80C -4962.0
PSMA8 -4966.0
WRN -4967.0
EIF5A -4972.0
SEC31A -4974.0
LRRC49 -4980.0
H2AC25 -4996.0
TRAPPC5 -5008.0
NLRP3 -5011.0
ELOB -5019.0
TGFA -5021.0
ASB8 -5033.0
PSMB8 -5035.0
COMMD2 -5050.0
UBD -5060.0
SEC24A -5095.0
TFPT -5150.0
TNIP2 -5153.0
ST8SIA4 -5159.0
LY6H -5243.0
WSB2 -5245.0
USP18 -5248.0
TMED3 -5250.0
SP3 -5253.0
SERPINA10 -5263.0
TUBAL3 -5273.0
ASXL1 -5302.0
DCUN1D4 -5308.0
THSD7B -5319.0
TUBA1A -5328.0
DCAF8 -5334.0
TTLL10 -5339.0
DCAF13 -5367.0
ST6GALNAC3 -5368.0
DPH3 -5371.0
ASB2 -5404.0
ADAMTSL2 -5417.0
WAC -5424.0
NSMCE4A -5425.0
SPSB2 -5435.0
DDX17 -5437.0
USP24 -5439.0
TMED9 -5443.0
METTL21A -5451.0
PSMB9 -5459.0
UBE2D3 -5466.0
NUP153 -5484.0
NAGK -5500.0
P4HB -5517.0
IL6 -5529.0
LSAMP -5530.0
UBE2R2 -5556.0
USP37 -5658.0
FBXL19 -5665.0
APOA1 -5666.0
PTEN -5671.0
NFKB2 -5732.0
SPON2 -5761.0
MBD1 -5762.0
PSMA6 -5784.0
GPS1 -5787.0
ASB1 -5815.0
COG6 -5816.0
TTLL3 -5824.0
GFPT2 -5827.0
PSMC2 -5834.0
ERCC8 -5839.0
MUC16 -5854.0
PSMC4 -5874.0
FBN1 -5910.0
GALNT9 -5926.0
C3 -5985.0
AGBL4 -5990.0
UBXN1 -5999.0
PRKCSH -6026.0
CP -6034.0
USP5 -6040.0
TNFAIP3 -6043.0
UBE2L3 -6065.0
RPN2 -6071.0
LTBP1 -6080.0
ADAMTS2 -6086.0
FBXL15 -6090.0
ARFGAP2 -6098.0
USO1 -6103.0
GALNT17 -6105.0
B3GNT5 -6115.0
SPSB1 -6117.0
DDX5 -6132.0
CNIH3 -6145.0
AXIN1 -6148.0
RAB25 -6150.0
NANS -6151.0
RAB22A -6160.0
H2AC1 -6184.0
SCG3 -6242.0
CHST8 -6271.0
B4GALT3 -6275.0
ING2 -6277.0
FUOM -6284.0
NFE2L2 -6307.0
THSD4 -6310.0
ASB16 -6345.0
NR1H4 -6356.0
SPSB4 -6362.0
KIN -6366.0
TTLL11 -6388.0
TUBB2A -6393.0
ALG2 -6396.0
FAM20C -6407.0
H2BC1 -6416.0
NUP88 -6429.0
ALG1 -6438.0
DNMT1 -6450.0
LYPD6B -6454.0
THSD1 -6460.0
RAB24 -6469.0
POM121 -6484.0
COPE -6497.0
PGR -6524.0
NFKBIA -6526.0
CUL9 -6534.0
UBB -6535.0
TTL -6547.0
VDR -6563.0
OTUD7A -6566.0
NUP62 -6573.0
LRRC41 -6589.0
PROC -6606.0
TNIP1 -6647.0
NPM1 -6656.0
CCP110 -6659.0
EDEM2 -6665.0
B4GALT2 -6693.0
PEX10 -6706.0
PIGC -6711.0
TTLL7 -6738.0
ADRM1 -6746.0
CGA -6754.0
ASB13 -6776.0
H2BC11 -6780.0
BET1L -6801.0
RAB27B -6812.0
H2BC26 -6814.0
LAMC1 -6839.0
AGBL3 -6842.0
PIGP -6848.0
FEM1A -6855.0
CHST10 -6872.0
CAPZA2 -6878.0
PSMC1 -6897.0
THBS1 -6908.0
CALR -6910.0
F2 -6955.0
NGLY1 -6980.0
HSPA8 -7000.0
H4C2 -7011.0
BCL10 -7068.0
GALNT15 -7086.0
LYPD4 -7111.0
UIMC1 -7124.0
COMMD10 -7133.0
RPN1 -7150.0
SPTA1 -7156.0
ACTR1A -7157.0
ST6GALNAC6 -7158.0
RAD21 -7170.0
ADAMTS3 -7176.0
TTLL6 -7190.0
PRKDC -7223.0
MUC17 -7245.0
CCNA1 -7274.0
MUC13 -7277.0
UBE2S -7305.0
UBC -7308.0
DERL1 -7323.0
RAB3B -7350.0
RNF20 -7365.0
DYNLL2 -7375.0
FBXL14 -7389.0
SEC23A -7400.0
ST8SIA1 -7424.0
RELA -7456.0
MGAT1 -7463.0
SUMO1 -7473.0
PSME3 -7475.0
ARSA -7476.0
UBE2N -7482.0
OTUB1 -7506.0
RNF40 -7512.0
TOP2B -7606.0
PSMB4 -7626.0
GRIA1 -7647.0
ADAMTSL3 -7653.0
SP100 -7668.0
PSMC5 -7743.0
ADAMTS18 -7747.0
NUP43 -7764.0
DOLK -7770.0
TRAPPC1 -7773.0
MAN1A1 -7783.0
MUC15 -7790.0
GOLM1 -7794.0
LYPD5 -7847.0
ALPL -7849.0
NUP42 -7851.0
FEM1C -7887.0
TPST1 -7889.0
GFPT1 -7897.0
SPRN -7901.0
IGFBP7 -7906.0
KBTBD8 -7930.0
H2AC16 -7951.0
GCNT1 -7958.0
FSTL3 -7980.0
GALNT14 -8006.0
TUBA8 -8057.0
PRND -8059.0
VGF -8085.0
SMC3 -8093.0
UBA52 -8101.0
STX5 -8109.0
ARSK -8160.0
CST3 -8175.0
ADAMTS4 -8177.0
UBE2B -8180.0
AGBL2 -8182.0
ARF5 -8184.0
NR1H3 -8193.0
KLHL41 -8213.0
CPM -8228.0
HIF3A -8290.0
RAB27A -8329.0
NOTUM -8331.0
TMED2 -8335.0
TP53 -8352.0
RAB14 -8366.0
ARF1 -8378.0
INO80E -8385.0
RAD23A -8423.0
ZNF131 -8425.0
NUP58 -8432.0
AGBL5 -8444.0
HNRNPC -8449.0
RPS2 -8500.0
F7 -8537.0
ST6GALNAC2 -8549.0
ASB17 -8560.0
TRAPPC4 -8585.0
MUC1 -8592.0
TF -8706.0
GPIHBP1 -8711.0
SEC24C -8716.0
RBBP5 -8717.0
B3GLCT -8737.0
JOSD1 -8744.0
FBXL3 -8756.0
H2AC8 -8778.0
TUBA3D -8798.0
ALG8 -8828.0
CDC20 -8838.0
ADAMTS7 -8850.0
PSCA -8853.0
MUC12 -8866.0
ST3GAL6 -8873.0
ST8SIA2 -8890.0
USP2 -8908.0
ADAMTS14 -8964.0
COG8 -8992.0
LAMB2 -9008.0
RTN4RL2 -9026.0
GALNT18 -9073.0
H2BC8 -9079.0
MFGE8 -9105.0
RAB31 -9148.0
B3GNT3 -9161.0
AHSG -9164.0
PIGW -9202.0
HRC -9234.0
ARSI -9238.0
UBE2C -9239.0
USP19 -9244.0
THY1 -9266.0
DAXX -9294.0
RAB3A -9326.0
ADAMTS1 -9373.0
B3GNT6 -9380.0
RIGI -9390.0
PAF1 -9433.0
TMEM129 -9455.0
DCTN1 -9474.0
PRSS21 -9484.0
SSPOP -9529.0
USP7 -9538.0
VCP -9546.0
CEACAM7 -9635.0
GALNTL5 -9658.0
ART4 -9678.0
ENAM -9690.0
COMMD5 -9735.0
UBA3 -9753.0
FEM1B -9776.0
POMK -9794.0
RAB26 -9796.0
TRIM28 -9819.0
SMC5 -9884.0
ANO8 -9886.0
DDA1 -9887.0
MUC5AC -9919.0
LY6D -9929.0
H2BC14 -9980.0
H2AC14 -10060.0
SKP1 -10072.0
MUC21 -10074.0
AMTN -10109.0
OBSL1 -10114.0
PDIA3 -10146.0
NEU3 -10152.0
PSMB10 -10166.0
B4GALT1 -10168.0
RNF7 -10204.0
ASB6 -10213.0
INO80B -10216.0
COL7A1 -10232.0
A4GNT -10237.0
FBXW10 -10255.0
LYPD2 -10272.0
FBXO40 -10295.0
PTRH2 -10325.0
ACTB -10333.0
MYSM1 -10337.0
RAET1L -10338.0
TUBA3E -10348.0
NUP85 -10353.0
NAE1 -10378.0
LMAN1L -10421.0
RTF1 -10427.0
MUC3A -10438.0
GOLGA2 -10502.0
SYVN1 -10538.0
ALG3 -10605.0
PIGT -10614.0
PPP6C -10624.0
IKBKE -10632.0
FOLR2 -10639.0
FSTL1 -10663.0
ALG10 -10710.0
LGALS1 -10742.0
SHISA5 -10762.0
OTOA -10775.0
SPACA4 -10800.0
ASGR2 -10832.0
ADAMTS13 -10836.0
MSLN -10855.0
C4A -10879.5
RAB6B -10928.0
MOGS -10964.0
AAAS -10980.0
POM121C -10983.0
SERPINA1 -11023.0
CEACAM5 -11083.0
UBE2Z -11089.0
ALPG -11233.0
RNF181 -11286.0
FOLR1 -11291.0
B3GNT7 -11511.0
TTLL2 -11538.0
PSMB11 -11624.0
LYPD8 -11718.0
IZUMO1R -11742.0
ASB10 -11835.0
CAPZA3 -11852.0
KDELR1 -11921.0
FUT3 -12042.0
FCGR3B -12065.0


REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM
484
set REACTOME_SELENOAMINO_ACID_METABOLISM
setSize 108
pANOVA 0.00119
s.dist -0.18
p.adjustANOVA 0.121



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAT1A -11542.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
MARS1 -10577.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAT1A -11542.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
MARS1 -10577.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
RPL37 -9383.0
RPL38 -9338.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
INMT -8282.0
UBA52 -8101.0
RPL35A -7809.0
RPS25 -7758.0
PAPSS2 -7718.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
RPL13 -6617.0
SCLY -6285.0
RPS20 -6260.0
TXNRD1 -5751.0
RPL41 -5634.0
RPS21 -5458.0
RPL23A -5311.0
GSR -5210.0
RPS24 -5072.0
RPL39L -5003.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
RPL3L -4049.0
RPL6 -4047.0
RPLP0 -3936.0
AIMP1 -3863.0
RPL36AL -3855.5
RPL12 -3714.0
RPL30 -3513.0
RPL35 -3180.0
LARS1 -3138.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
NNMT -1777.0
CTH -1743.0
RPS3 -1606.0
KARS1 -1449.0
RPL22 -1193.0
RPS29 -1088.0
RPL17 -837.0
RPL5 -544.0
PAPSS1 -249.0
RPS11 -225.0
RPL26 -28.0
AIMP2 347.0
RPL27A 454.0
SEPSECS 644.0
EEFSEC 804.0
RPL19 1027.0
RPL11 1163.0
RPS16 1311.0
RPS27A 1837.0
IARS1 1852.0
RPLP1 2863.0
GNMT 3174.0
RARS1 3783.0
RPL34 3847.0
RPS9 4427.0
EEF1E1 4465.0
RPL37A 4707.0
EPRS1 5174.0
SECISBP2 5277.0
RPL15 5290.0
RPL26L1 5864.0
DARS1 6010.0
SEPHS2 6564.0
RPL32 7009.0
RPS19 7158.0
PSTK 7430.0
RPS27 7711.0
HNMT 8004.0
RPS14 8094.0
RPL31 8401.0
AHCY 8459.0
RPL10L 9197.0


REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
601
set REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize 188
pANOVA 0.00125
s.dist -0.136
p.adjustANOVA 0.121



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
EDN2 -11812
CCR6 -11704
CXCR5 -11616
CCL20 -11615
CCL1 -11605
CCL13 -11584
CCL5 -11555
PPBP -11501
PROKR1 -11261
RXFP4 -11248
CX3CR1 -11186
NPFF -11121
C5AR1 -11113
ACKR2 -11069

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
EDN2 -11812
CCR6 -11704
CXCR5 -11616
CCL20 -11615
CCL1 -11605
CCL13 -11584
CCL5 -11555
PPBP -11501
PROKR1 -11261
RXFP4 -11248
CX3CR1 -11186
NPFF -11121
C5AR1 -11113
ACKR2 -11069
KEL -11029
PROK1 -11025
F2RL2 -11008
NPBWR2 -10976
CXCL10 -10918
ACKR1 -10882
CCR5 -10843
F2RL3 -10796
EDNRA -10732
AGT -10682
SAA1 -10622
GALR3 -10505
CCL21 -10468
CX3CL1 -10395
FPR2 -10391
RLN3 -10264
APLNR -10187
CCL11 -10184
UTS2 -10158
CXCL12 -10139
NPFFR1 -10084
CCL23 -9956
C5AR2 -9813
AVPR1B -9803
NPY5R -9752
CCL19 -9668
CCL27 -9397
PNOC -9350
QRFP -9327
CCKBR -9263
NPSR1 -9249
EDN1 -9154
GRP -9139
UTS2B -9125
PDYN -9088
NMBR -8991
CXCL5 -8881
CCL2 -8841
CCL17 -8684
TACR2 -8616
GPR37L1 -8548
NPY -8526
CXCL9 -8044
TAC1 -7957
NMS -7934
NPBWR1 -7813
NMUR1 -7471
NPY2R -7413
BDKRB2 -7167
F2 -6955
GAL -6918
PYY -6904
PMCH -6742
GALR2 -6733
CCR10 -6085
F2R -6072
C3 -5985
FPR3 -5898
OPRL1 -5660
GPER1 -5597
NTSR1 -5379
MC1R -5172
OXTR -5097
AGTR1 -4920
TACR3 -4814
MLN -4744
PPY -4632
CXCL13 -4617
EDN3 -4593
BDKRB1 -4562
KISS1 -4245
MC2R -4210
CXCL16 -3961
INSL5 -3870
NPS -3203
RXFP1 -3179
PRLHR -3098
APP -3074
CXCL3 -2985
KNG1 -2955
CXCR2 -2896
NPW -2876
NTSR2 -2798
EDNRB -2656
OPRM1 -2352
CXCR4 -2312
CCK -2171
OPRK1 -2124
RLN2 -2037
SSTR2 -1673
CCR8 -1546
ECE2 -1384
HCRTR1 -1264
SST -1115
GALR1 -530
NMU -419
POMC -331
PROKR2 -292
PROK2 -126
MC3R 483
TRH 599
C5 686
MLNR 1051
C3AR1 1333
ACKR3 2034
HEBP1 2371
CORT 2395
MCHR1 2471
PSAP 2542
NTS 2849
TACR1 2882
CXCR6 3143
SSTR5 3339
AVPR1A 3341
NPY1R 3677
MCHR2 3692
OPRD1 3708
CXCR1 3879
HCRTR2 4016
KISS1R 4153
PENK 4420
HCRT 4431
ECE1 4525
GHRL 4611
RXFP2 4861
XCL1 4984
FPR1 5077
CCKAR 5086
ANXA1 5126
GHSR 5169
CXCL8 5213
TRHR 5668
ACKR4 5792
SSTR3 5835
CXCL2 5948
INSL3 6113
CCR7 6179
NLN 6295
XCL2 6376
MC4R 6494
XCR1 6784
NMUR2 6859
F2RL1 7056
CCR2 7161
RXFP3 7275
CCL28 7436
GPR37 7511
SSTR4 7518
PF4 7540
CCR4 7589
CCL3 7624
CCR3 7679
PRLH 7813
NPB 7864
QRFPR 7876
NMB 7928
CCL25 8003
MC5R 8225
CCRL2 8328
SSTR1 8425
NPFFR2 8447
UTS2R 8799
CXCL6 9000
CCR1 9067
OXT 9140
CXCL11 9340
CXCL1 9475
CCR9 9543


REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 0.00126
s.dist -0.153
p.adjustANOVA 0.121



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPL29 -11475.0
ISG15 -11218.0
RPL18 -11061.0
RPLP2 -11033.0
POM121C -10983.0
AAAS -10980.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
NUP85 -10353.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
HSP90AA1 -10062.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPL29 -11475.0
ISG15 -11218.0
RPL18 -11061.0
RPLP2 -11033.0
POM121C -10983.0
AAAS -10980.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
NUP85 -10353.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
HSP90AA1 -10062.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
POLR2F -9908.0
RPS8 -9901.0
RPL7 -9769.0
KPNA4 -9740.0
RPL37 -9383.0
RPL38 -9338.0
KPNB1 -9278.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
NUP58 -8432.0
RPS18 -8407.0
PABPN1 -8344.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
POLR2K -8099.0
NUP42 -7851.0
RPL35A -7809.0
NUP43 -7764.0
RPS25 -7758.0
KPNA5 -7651.0
RPS5 -7280.0
POLR2L -7198.0
RPS13 -7029.0
RPS6 -6939.0
CALR -6910.0
RPL13 -6617.0
NUP62 -6573.0
CLTA -6520.0
POM121 -6484.0
NUP88 -6429.0
POLR2E -6392.0
RPS20 -6260.0
XPO1 -5699.0
RPL41 -5634.0
NUP153 -5484.0
RPS21 -5458.0
RPL23A -5311.0
POLR2J -5102.0
RPS24 -5072.0
RPL39L -5003.0
RPL22L1 -4795.0
RPS23 -4737.0
RPL7A -4508.0
POLR2I -4452.0
TGFB1 -4255.0
RPL3L -4049.0
RPL6 -4047.0
NUP50 -3986.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
RPL30 -3513.0
KPNA7 -3390.0
RPL35 -3180.0
RPL24 -2999.0
NUP133 -2987.0
RANBP2 -2965.0
RPS7 -2847.0
RPSA -2801.0
CPSF4 -2716.0
RPL9 -2423.0
RPS27L -2334.0
POLR2C -2257.0
RPS26 -2128.0
RAN -2120.0
RPL28 -2101.0
HSPA1A -1697.0
RPS3 -1606.0
RPL22 -1193.0
RPS29 -1088.0
POLR2D -1016.0
RPL17 -837.0
RPL5 -544.0
RPS11 -225.0
RPL26 -28.0
RPL27A 454.0
KPNA3 596.0
NUP205 632.0
RPL19 1027.0
KPNA2 1103.0
RPL11 1163.0
RPS16 1311.0
NUP107 1476.0
NUP155 1514.0
RPS27A 1837.0
SEC13 1952.0
NUP188 2071.0
RAE1 2123.0
GTF2F2 2390.0
GRSF1 2426.0
KPNA1 2598.0
GTF2F1 2819.0
DNAJC3 2833.0
RPLP1 2863.0
NUP37 3040.0
POLR2H 3403.0
NUP214 3453.0
RPL34 3847.0
NUP160 4345.0
IPO5 4350.0
RPS9 4427.0
NUP210 4646.0
NDC1 4699.0
RPL37A 4707.0
NUP35 4738.0
NUP98 4773.0
CLTC 5050.0
RPL15 5290.0
NUP93 5581.0
POLR2A 5585.0
RPL26L1 5864.0
POLR2B 6148.0
CANX 6158.0
PARP1 6591.0
RPL32 7009.0
SEH1L 7023.0
TPR 7143.0
RPS19 7158.0
RPS27 7711.0
NUP54 7883.0
RPS14 8094.0
RPL31 8401.0
EIF2AK2 8638.0
POLR2G 8755.0
RPL10L 9197.0


REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION

REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION
213
set REACTOME_LECTIN_PATHWAY_OF_COMPLEMENT_ACTIVATION
setSize 8
pANOVA 0.00142
s.dist -0.651
p.adjustANOVA 0.129



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
MASP1 -10383
FCN3 -10157
MBL2 -9077
COLEC10 -5455
COLEC11 -5126
MASP2 -3170

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
MASP1 -10383
FCN3 -10157
MBL2 -9077
COLEC10 -5455
COLEC11 -5126
MASP2 -3170


REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING
834
set REACTOME_GPCR_LIGAND_BINDING
setSize 444
pANOVA 0.00171
s.dist -0.0868
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
UCN2 -12032
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
TAS2R39 -11899
GPHA2 -11875
EDN2 -11812
CCR6 -11704
IAPP -11660
TAS1R3 -11649
CXCR5 -11616
CCL20 -11615
FSHB -11607
CCL1 -11605
CCL13 -11584
SUCNR1 -11581
CCL5 -11555

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
UCN2 -12032
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
TAS2R39 -11899
GPHA2 -11875
EDN2 -11812
CCR6 -11704
IAPP -11660
TAS1R3 -11649
CXCR5 -11616
CCL20 -11615
FSHB -11607
CCL1 -11605
CCL13 -11584
SUCNR1 -11581
CCL5 -11555
GHRH -11527
PPBP -11501
GPR132 -11441
RAMP3 -11437
CMKLR1 -11353
P2RY2 -11337
PROKR1 -11261
RXFP4 -11248
CX3CR1 -11186
LTB4R2 -11180
NPFF -11121
C5AR1 -11113
ADGRE2 -11078
ACKR2 -11069
KEL -11029
PROK1 -11025
F2RL2 -11008
FZD4 -10991
NPBWR2 -10976
CXCL10 -10918
TAS2R4 -10892
ACKR1 -10882
TAS2R43 -10850
CCR5 -10843
TAS2R13 -10820
F2RL3 -10796
ADORA1 -10781
EDNRA -10732
SMO -10723
AGT -10682
SAA1 -10622
ADRA2B -10619
ADCYAP1R1 -10607
GALR3 -10505
CCL21 -10468
ADRA1D -10425
CX3CL1 -10395
FPR2 -10391
RHO -10342
WNT11 -10298
RLN3 -10264
APLNR -10187
CCL11 -10184
UTS2 -10158
CXCL12 -10139
NPFFR1 -10084
CCL23 -9956
GHRHR -9874
LHCGR -9858
C5AR2 -9813
AVPR1B -9803
NPY5R -9752
CHRM4 -9709
CCL19 -9668
TAS2R40 -9648
SCTR -9600
CALCRL -9592
GPR4 -9574
PLPPR3 -9553
GABBR2 -9485
WNT9B -9439
CCL27 -9397
PNOC -9350
QRFP -9327
DRD2 -9303
GPRC6A -9301
CCKBR -9263
NPSR1 -9249
EDN1 -9154
GRP -9139
UTS2B -9125
VIP -9096
P2RY11 -9090
PDYN -9088
NMBR -8991
FZD8 -8937
HTR5A -8917
CXCL5 -8881
CHRM3 -8878
TAS2R9 -8868
PLPPR2 -8867
CCL2 -8841
TAS2R41 -8779
PTH2R -8773
WNT8A -8693
CCL17 -8684
CHRM1 -8632
FSHR -8623
TACR2 -8616
P2RY6 -8575
GPR37L1 -8548
NPY -8526
GNRHR -8492
RGR -8468
CRHR1 -8420
LTB4R -8403
ADRA1B -8348
VIPR2 -8324
S1PR4 -8278
TAS2R8 -8192
CXCL9 -8044
GPR55 -7997
GRM4 -7974
GPBAR1 -7960
TAC1 -7957
ADORA2B -7945
ADM2 -7937
NMS -7934
LPAR2 -7861
NPBWR1 -7813
TAS1R1 -7788
TAS2R16 -7742
TAS2R38 -7698
FZD9 -7527
NMUR1 -7471
HRH1 -7438
LPAR1 -7430
WNT3A -7414
NPY2R -7413
RAMP1 -7363
TAS2R3 -7236
BDKRB2 -7167
F2 -6955
GPR183 -6922
GAL -6918
PYY -6904
CNR1 -6794
GCG -6774
HRH4 -6767
CGA -6754
PMCH -6742
GALR2 -6733
GNG13 -6611
HTR4 -6557
GNG5 -6508
GPR39 -6458
GNGT2 -6419
FZD7 -6331
CRHBP -6326
ADGRE5 -6319
HRH2 -6296
OXER1 -6157
CCR10 -6085
F2R -6072
ADRA1A -6046
C3 -5985
FPR3 -5898
OPN5 -5826
TAS1R2 -5814
CRHR2 -5746
HTR2A -5729
OPRL1 -5660
GPER1 -5597
NTSR1 -5379
MC1R -5172
HTR1A -5146
OXTR -5097
ADRB1 -4982
S1PR1 -4978
IHH -4950
AGTR1 -4920
GPR68 -4913
PTCH2 -4871
CD55 -4870
TACR3 -4814
MLN -4744
FZD6 -4650
PPY -4632
CXCL13 -4617
EDN3 -4593
BDKRB1 -4562
SCT -4517
GNG12 -4514
GNB1 -4430
FFAR4 -4371
PTH1R -4345
GNRH2 -4274
HRH3 -4261
KISS1 -4245
MC2R -4210
UCN -4138
GNB2 -4027
CXCL16 -3961
WNT4 -3871
INSL5 -3870
PTGER3 -3853
GRM1 -3850
VIPR1 -3808
FFAR2 -3662
GABBR1 -3633
CHRM2 -3573
TBXA2R -3546
GPR35 -3377
NPS -3203
RXFP1 -3179
PRLHR -3098
APP -3074
WNT7A -3003
CXCL3 -2985
KNG1 -2955
GPR17 -2926
TAS2R42 -2918
CXCR2 -2896
NPW -2876
FZD1 -2826
NTSR2 -2798
EDNRB -2656
PTHLH -2647
P2RY14 -2604
HTR1B -2506
GRM2 -2469
OPRM1 -2352
TAS2R5 -2330
CXCR4 -2312
TAAR5 -2291
CCK -2171
OPRK1 -2124
LPAR3 -2109
CASR -2065
GNG2 -2064
HTR7 -2042
PLPPR5 -2039
RLN2 -2037
ADM -1995
GIPR -1978
CRH -1854
GNB4 -1791
WNT6 -1752
SSTR2 -1673
P2RY1 -1654
PTH2 -1636
CCR8 -1546
PLPPR1 -1538
WNT10B -1453
ECE2 -1384
HCRTR1 -1264
CNR2 -1235
SST -1115
GNG4 -1001
HTR1F -967
TSHR -838
WNT9A -797
GNG7 -716
WNT2B -641
GALR1 -530
GLP2R -451
NMU -419
POMC -331
PROKR2 -292
OPN1SW -141
DRD1 -132
PROK2 -126
GRM8 -86
S1PR2 16
S1PR5 49
GRM5 160
HTR6 169
MC3R 483
FZD3 546
TRH 599
P2RY13 677
WNT7B 680
C5 686
WNT1 921
PTGDR 946
GLP1R 995
MLNR 1051
ADRB2 1122
C3AR1 1333
CALCR 1507
LPAR5 1531
GNG10 1595
GNRH1 1661
ADCYAP1 1982
ACKR3 2034
GRM3 2133
HEBP1 2371
CORT 2395
MCHR1 2471
PSAP 2542
WNT10A 2607
MTNR1A 2609
PTGDR2 2704
NTS 2849
TACR1 2882
TSHB 2901
GNG3 2935
GPR18 3120
CXCR6 3143
WNT16 3163
WNT8B 3241
SSTR5 3339
AVPR1A 3341
FZD10 3348
FZD5 3450
GRM7 3497
P2RY12 3523
TAAR2 3605
PLPPR4 3625
NPY1R 3677
MCHR2 3692
OPRD1 3708
HTR1E 3852
CXCR1 3879
PTGIR 3883
OPN3 3942
OPN4 3977
HCRTR2 4016
PTGFR 4034
WNT3 4085
KISS1R 4153
ADGRE1 4213
CALCB 4339
HTR1D 4372
GNAS 4399
PENK 4420
HCRT 4431
CALCA 4467
ECE1 4525
PTGER4 4574
GHRL 4611
GNB5 4614
RXFP2 4861
XCL1 4984
RAMP2 5053
FPR1 5077
CCKAR 5086
ANXA1 5126
TAS2R14 5162
GHSR 5169
CXCL8 5213
DRD3 5227
CHRM5 5253
ADRB3 5364
WNT5A 5593
DHH 5660
TRHR 5668
PTCH1 5675
TAAR8 5729
PTGER1 5752
ACKR4 5792
WNT2 5832
SSTR3 5835
CXCL2 5948
INSL3 6113
CCR7 6179
ADRA2C 6213
SHH 6249
NLN 6295
XCL2 6376
FZD2 6467
MC4R 6494
GNG8 6554
HCAR1 6641
GRM6 6662
LPAR6 6681
GIP 6722
PTH 6779
XCR1 6784
PTGER2 6791
NMUR2 6859
GNG11 6922
F2RL1 7056
TAS2R30 7127
MTNR1B 7134
CCR2 7161
ADRA2A 7162
TAS2R1 7175
RXFP3 7275
CCL28 7436
PTAFR 7505
GPR37 7511
SSTR4 7518
PF4 7540
CCR4 7589
CCL3 7624
CCR3 7679
GNB3 7772
TAS2R7 7780
RRH 7801
PRLH 7813
DRD5 7822
TAAR9 7856
NPB 7864
QRFPR 7876
NMB 7928
CCL25 8003
TAS2R19 8132
DRD4 8219
MC5R 8225
TAS2R50 8265
UCN3 8313
CCRL2 8328
SSTR1 8425
TAS2R20 8430
GPR31 8435
NPFFR2 8447
FFAR1 8545
TAS2R10 8565
TAAR1 8771
UTS2R 8799
HTR2B 8869
OXGR1 8930
ADORA3 8933
CXCL6 9000
CCR1 9067
FFAR3 9102
OXT 9140
TAS2R31 9211
TAS2R46 9224
GPR65 9229
LHB 9274
CXCL11 9340
GPHB5 9404
GNGT1 9442
HCAR2 9458
ADORA2A 9467
CXCL1 9475
CYSLTR2 9512
ADGRE3 9526
CCR9 9543
TAAR6 9544
TAS2R60 9563
S1PR3 9641


REACTOME_SUMOYLATION

REACTOME_SUMOYLATION
531
set REACTOME_SUMOYLATION
setSize 179
pANOVA 0.0018
s.dist 0.135
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF350 9542
SUZ12 9441
SATB1 9382
BMI1 9147
NR1H2 8734
H4C12 8556
RWDD3 8334
H4C5 8212
DNMT3B 8185
CREBBP 8084
NUP54 7883
TOP1 7768
HDAC4 7743
CBX5 7575
HERC2 7326
HDAC1 7322
RPA1 7231
TPR 7143
FOXL2 7095
SEH1L 7023

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF350 9542
SUZ12 9441
SATB1 9382
BMI1 9147
NR1H2 8734
H4C12 8556
RWDD3 8334
H4C5 8212
DNMT3B 8185
CREBBP 8084
NUP54 7883
TOP1 7768
HDAC4 7743
CBX5 7575
HERC2 7326
HDAC1 7322
RPA1 7231
TPR 7143
FOXL2 7095
SEH1L 7023
PPARG 6934
UBA2 6702
PARP1 6591
AURKB 6511
TFAP2A 6366
INCENP 6349
CBX2 6305
H4C3 6009
NR4A2 5917
TFAP2B 5723
PPARGC1A 5699
NUP93 5581
PPARA 5527
XPC 5431
NRIP1 5403
ESR1 5343
H4C9 5306
PIAS1 5064
SUMO2 5002
CTBP1 4983
PHC3 4830
SENP5 4796
NUP98 4773
NUP35 4738
EID3 4723
H4C6 4702
NDC1 4699
NUP210 4646
MDC1 4416
PIAS4 4387
NUP160 4345
UBE2I 4284
RNF168 4092
RARA 4076
L3MBTL2 4072
PCNA 4020
SCMH1 3707
TP53BP1 3700
PIAS2 3666
HDAC2 3563
TFAP2C 3482
DNMT3A 3470
NUP214 3453
SUMO3 3428
UHRF2 3294
MTA1 3198
BIRC5 3110
NSMCE3 3100
NUP37 3040
H4C16 2844
NR5A2 2788
HDAC7 2503
CBX4 2447
H4C1 2332
PML 2311
TRIM27 2257
RAE1 2123
HNRNPK 2120
NUP188 2071
MITF 1977
SENP2 1955
SEC13 1952
CHD3 1941
TDG 1826
NCOR2 1788
RNF2 1715
SENP1 1573
NUP155 1514
NUP107 1476
TOP2A 1336
RXRA 1224
BRCA1 1137
PIAS3 983
VHL 843
TOPORS 689
NUP205 632
MRTFA 400
PHC1 323
STAG1 281
NR2C1 104
EP300 15
SIN3A -19
THRA -89
NR5A1 -557
HIPK2 -843
SAFB -1061
RANGAP1 -1150
SAE1 -1482
NCOA2 -1529
PCGF2 -1542
MDM2 -1544
CBX8 -1633
SATB2 -1663
RING1 -1753
NSMCE2 -1806
RAD52 -1965
SMC6 -2043
AURKA -2075
XRCC4 -2238
PARK7 -2427
RORA -2435
CDCA8 -2485
H4C13 -2630
H4C4 -2649
PHC2 -2666
H4C8 -2728
RANBP2 -2965
NUP133 -2987
NOP58 -3224
NSMCE1 -3303
NR1I2 -3341
H4C11 -3485
HIC1 -3557
CDKN2A -3687
NR3C2 -3735
NR3C1 -3781
NUP50 -3986
BLM -4634
NCOA1 -4726
THRB -4734
WRN -4967
SP3 -5253
NSMCE4A -5425
DDX17 -5437
NUP153 -5484
NFKB2 -5732
MBD1 -5762
DDX5 -6132
ING2 -6277
NR1H4 -6356
NUP88 -6429
DNMT1 -6450
POM121 -6484
PGR -6524
NFKBIA -6526
VDR -6563
NUP62 -6573
NPM1 -6656
H4C2 -7011
RAD21 -7170
RELA -7456
SUMO1 -7473
TOP2B -7606
SP100 -7668
NUP43 -7764
NUP42 -7851
SMC3 -8093
NR1H3 -8193
TP53 -8352
ZNF131 -8425
NUP58 -8432
HNRNPC -8449
DAXX -9294
TRIM28 -9819
SMC5 -9884
NUP85 -10353
IKBKE -10632
AAAS -10980
POM121C -10983


REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA

REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA
499
set REACTOME_INTERACTION_WITH_CUMULUS_CELLS_AND_THE_ZONA_PELLUCIDA
setSize 11
pANOVA 0.00246
s.dist -0.527
p.adjustANOVA 0.188



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZP2 -10741
ZP4 -10481
B4GALT1 -10168
OVGP1 -10077
ZP1 -10016
ADAM20 -8384
SPAM1 -6152
ZP3 -5542
ADAM2 -3190
ADAM21 -1410
ADAM30 -330

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZP2 -10741
ZP4 -10481
B4GALT1 -10168
OVGP1 -10077
ZP1 -10016
ADAM20 -8384
SPAM1 -6152
ZP3 -5542
ADAM2 -3190
ADAM21 -1410
ADAM30 -330


REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS
818
set REACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS
setSize 68
pANOVA 0.00252
s.dist 0.212
p.adjustANOVA 0.188



Top enriched genes

Top 20 genes
GeneID Gene Rank
SUZ12 9441
SATB1 9382
BMI1 9147
H4C12 8556
H4C5 8212
NUP54 7883
HDAC4 7743
CBX5 7575
HDAC1 7322
TPR 7143
SEH1L 7023
CBX2 6305
H4C3 6009
NUP93 5581
H4C9 5306
PIAS1 5064
SUMO2 5002
PHC3 4830
NUP98 4773
NUP35 4738

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SUZ12 9441
SATB1 9382
BMI1 9147
H4C12 8556
H4C5 8212
NUP54 7883
HDAC4 7743
CBX5 7575
HDAC1 7322
TPR 7143
SEH1L 7023
CBX2 6305
H4C3 6009
NUP93 5581
H4C9 5306
PIAS1 5064
SUMO2 5002
PHC3 4830
NUP98 4773
NUP35 4738
H4C6 4702
NDC1 4699
NUP210 4646
NUP160 4345
UBE2I 4284
L3MBTL2 4072
SCMH1 3707
PIAS2 3666
HDAC2 3563
NUP214 3453
SUMO3 3428
NUP37 3040
H4C16 2844
CBX4 2447
H4C1 2332
RAE1 2123
NUP188 2071
SEC13 1952
CHD3 1941
RNF2 1715
NUP155 1514
NUP107 1476
NUP205 632
PHC1 323
PCGF2 -1542
CBX8 -1633
SATB2 -1663
RING1 -1753
H4C13 -2630
H4C4 -2649
PHC2 -2666
H4C8 -2728
RANBP2 -2965
NUP133 -2987
H4C11 -3485
NUP50 -3986
NUP153 -5484
NUP88 -6429
POM121 -6484
NUP62 -6573
H4C2 -7011
SUMO1 -7473
NUP43 -7764
NUP42 -7851
NUP58 -8432
NUP85 -10353
AAAS -10980
POM121C -10983


REACTOME_DEUBIQUITINATION

REACTOME_DEUBIQUITINATION
1000
set REACTOME_DEUBIQUITINATION
setSize 260
pANOVA 0.00292
s.dist 0.107
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
TGFBR1 9195.0
RIPK1 8935.0
H2AC17 8661.0
AXIN2 8621.0
H2BC17 8591.0
PSMD13 8524.0
RNF135 8451.0
USP33 8337.0
RNF146 8213.0
SMURF2 8023.0
TRAF6 7953.0
NFRKB 7929.0
PSMF1 7714.0
ACTR8 7667.0
BABAM1 7457.0
CDK1 7310.0
PSMD11 7309.0
H2BC9 7299.5
FOXK1 7245.0
ATXN3 7075.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TGFBR1 9195.0
RIPK1 8935.0
H2AC17 8661.0
AXIN2 8621.0
H2BC17 8591.0
PSMD13 8524.0
RNF135 8451.0
USP33 8337.0
RNF146 8213.0
SMURF2 8023.0
TRAF6 7953.0
NFRKB 7929.0
PSMF1 7714.0
ACTR8 7667.0
BABAM1 7457.0
CDK1 7310.0
PSMD11 7309.0
H2BC9 7299.5
FOXK1 7245.0
ATXN3 7075.0
YOD1 6974.0
PSME4 6905.0
USP16 6904.0
PSMA2 6867.0
KAT2A 6840.0
STAM2 6747.0
OTUD3 6737.0
USP8 6699.0
PSMC6 6685.0
SUDS3 6676.0
TNKS 6617.0
CLSPN 6574.0
IFIH1 6444.0
OTUB2 6363.0
TGFBR2 6348.0
UFD1 6292.0
PSMB6 6285.0
MAVS 6186.0
USP15 6151.0
TRRAP 6116.0
NOD1 6079.0
USP22 6064.0
IL33 5933.0
USP44 5862.0
H2BC12 5854.0
UCHL5 5797.0
RIPK2 5784.0
TNIP3 5762.0
H2AC4 5676.0
H2AC20 5583.0
INO80 5468.0
PSMD9 5439.0
MDM4 5418.0
USP42 5408.0
ZRANB1 5383.0
USP4 5372.0
UCHL1 5365.0
ESR1 5343.0
BABAM2 5265.0
CCNA2 5259.0
PSMD7 5071.0
USP28 5019.0
PSMB3 4905.0
PSMB7 4896.0
USP21 4866.0
SIAH2 4839.0
ABRAXAS2 4718.0
FKBP8 4676.0
USP30 4671.0
WDR20 4666.0
ASXL2 4659.0
WDR48 4502.0
ATXN7 4231.0
H2BC13 4070.0
PSMB1 4033.0
TADA2B 4019.0
PSMA5 4001.0
PSMD14 3838.0
H2AC7 3829.5
H2BC7 3829.5
H2BC6 3659.0
SMAD2 3580.0
ARRB1 3508.0
SMAD1 3494.0
CDC25A 3199.0
RUVBL1 3185.0
H2AC18 3107.5
H2AC19 3107.5
VCPIP1 3089.0
PSMD12 3007.0
MCRS1 2987.0
BIRC3 2918.0
PRKN 2779.0
PSMA4 2616.0
USP25 2614.0
PSME1 2536.0
USP13 2456.0
VDAC1 2375.0
MAT2B 2218.0
RHOT1 2161.0
STAMBPL1 2082.0
BIRC2 2041.0
NOD2 2013.0
RAD23B 1983.0
SMAD4 1939.0
INO80D 1853.0
RPS27A 1837.0
USP14 1770.0
CYLD 1689.0
KDM1B 1558.0
TOMM70 1537.0
KEAP1 1532.0
TAB1 1505.0
H2BC4 1347.0
HGS 1269.0
USP20 1260.0
GATA3 1188.0
BRCA1 1137.0
ADRB2 1122.0
TRAF2 1082.0
H2AC6 949.0
USP12 935.0
PSMD1 886.0
RNF123 749.0
H2BC21 723.0
USP47 674.0
PSMD6 572.0
PSMC3 570.0
PSMB2 533.0
USP3 532.0
PSMD8 460.0
H2AC11 355.0
PSMA3 337.0
H2AC12 334.0
PSMD5 170.0
UBE2D1 159.0
NEDD8 47.0
EP300 15.0
H2BC5 -9.0
SKP2 -107.0
SNX3 -291.0
H2AC13 -397.0
YY1 -511.0
SEM1 -525.0
MAP3K7 -559.0
SMAD7 -785.0
PSMA1 -810.0
IDE -847.0
USP34 -951.0
TRIM4 -1009.0
H2BC10 -1032.0
POLB -1123.0
TRAF3 -1175.0
ABRAXAS1 -1380.0
H2AC21 -1383.0
H2BC15 -1414.0
SENP8 -1431.0
MUL1 -1486.0
MDM2 -1544.0
ARRB2 -1550.0
APC -1598.0
MBD5 -1867.0
FOXK2 -1893.0
USP10 -2148.0
PSME2 -2199.0
TADA3 -2200.0
USP49 -2233.0
TRIM25 -2264.0
ACTL6A -2279.0
DDB2 -2351.0
TAF10 -2376.0
PSMD4 -2411.0
VDAC3 -2460.0
MBD6 -2555.0
H2AC15 -2567.0
ACTR5 -2607.0
OTUD7B -2670.0
KAT2B -2785.0
UCHL3 -2886.0
RCE1 -2901.0
H2BC3 -2958.0
BAP1 -3235.0
TNKS2 -3536.0
BECN1 -3611.0
HIF1A -3630.0
VDAC2 -3672.0
SMAD3 -3680.0
TOMM20 -3842.0
JOSD2 -3843.0
CFTR -3968.0
TGFB1 -4255.0
STAM -4324.0
PSMB5 -4359.0
MYC -4660.0
RHOA -4678.0
BARD1 -4746.0
STAMBP -4770.0
PSMD3 -4790.0
PSMD2 -4823.0
USP48 -4948.0
PSMA7 -4955.0
INO80C -4962.0
PSMA8 -4966.0
H2AC25 -4996.0
NLRP3 -5011.0
PSMB8 -5035.0
TFPT -5150.0
TNIP2 -5153.0
USP18 -5248.0
ASXL1 -5302.0
USP24 -5439.0
PSMB9 -5459.0
USP37 -5658.0
PTEN -5671.0
PSMA6 -5784.0
PSMC2 -5834.0
PSMC4 -5874.0
USP5 -6040.0
TNFAIP3 -6043.0
AXIN1 -6148.0
H2AC1 -6184.0
H2BC1 -6416.0
NFKBIA -6526.0
UBB -6535.0
OTUD7A -6566.0
TNIP1 -6647.0
CCP110 -6659.0
ADRM1 -6746.0
H2BC11 -6780.0
H2BC26 -6814.0
PSMC1 -6897.0
UIMC1 -7124.0
CCNA1 -7274.0
UBC -7308.0
PSME3 -7475.0
OTUB1 -7506.0
PSMB4 -7626.0
PSMC5 -7743.0
H2AC16 -7951.0
UBA52 -8101.0
TP53 -8352.0
INO80E -8385.0
RAD23A -8423.0
JOSD1 -8744.0
H2AC8 -8778.0
CDC20 -8838.0
USP2 -8908.0
H2BC8 -9079.0
USP19 -9244.0
RIGI -9390.0
USP7 -9538.0
VCP -9546.0
H2BC14 -9980.0
H2AC14 -10060.0
PSMB10 -10166.0
INO80B -10216.0
PTRH2 -10325.0
ACTB -10333.0
MYSM1 -10337.0
PSMB11 -11624.0


REACTOME_SIGNALING_BY_WNT

REACTOME_SIGNALING_BY_WNT
343
set REACTOME_SIGNALING_BY_WNT
setSize 318
pANOVA 0.00294
s.dist 0.097
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKK4 9504
GNGT1 9442
AGO1 9194
H3C1 9085
GNAT2 9039
H2AZ2 8952
AXIN2 8621
H2BC17 8591
H4C12 8556
PSMD13 8524
CTNNBIP1 8312
FRAT2 8272
PPP2R5D 8269
RNF146 8213
H4C5 8212
CREBBP 8084
LEF1 8081
PLCB2 8065
SMURF2 8023
PPP2R5B 7999

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKK4 9504.0
GNGT1 9442.0
AGO1 9194.0
H3C1 9085.0
GNAT2 9039.0
H2AZ2 8952.0
AXIN2 8621.0
H2BC17 8591.0
H4C12 8556.0
PSMD13 8524.0
CTNNBIP1 8312.0
FRAT2 8272.0
PPP2R5D 8269.0
RNF146 8213.0
H4C5 8212.0
CREBBP 8084.0
LEF1 8081.0
PLCB2 8065.0
SMURF2 8023.0
PPP2R5B 7999.0
KMT2D 7924.0
GNB3 7772.0
PPP2R1B 7726.0
PSMF1 7714.0
RBX1 7648.0
H3-4 7608.0
HDAC1 7322.0
PSMD11 7309.0
H2BC9 7299.5
H3C7 7299.5
TCF7 7254.0
GNG11 6922.0
PSME4 6905.0
PSMA2 6867.0
SOX17 6863.0
CHD8 6777.0
TNRC6C 6711.0
USP8 6699.0
PSMC6 6685.0
TNKS 6617.0
GNG8 6554.0
SOX7 6477.0
FZD2 6467.0
PSMB6 6285.0
BCL9L 6272.0
AKT2 6231.0
TRRAP 6116.0
H4C3 6009.0
H2BC12 5854.0
WNT2 5832.0
PPP2R5A 5717.0
H2AC4 5676.0
WNT5A 5593.0
H2AC20 5583.0
H3C8 5547.0
PSMD9 5439.0
CSNK2B 5425.0
RNF43 5405.0
ZRANB1 5383.0
H4C9 5306.0
RAC3 5256.0
NLK 5109.0
SFRP2 5101.0
PSMD7 5071.0
CLTC 5050.0
CSNK1G2 5013.0
PRKCB 4990.0
CTBP1 4983.0
ASH2L 4906.0
PSMB3 4905.0
PSMB7 4896.0
PRKCA 4876.0
AGO2 4867.0
H4C6 4702.0
YWHAZ 4640.0
GNB5 4614.0
PARD6A 4581.5
CLTB 4542.0
AP2B1 4519.0
PPP2R5C 4507.0
AP2M1 4358.0
AP2A2 4289.0
CCDC88C 4236.0
H3-3A 4158.0
CTNNB1 4100.0
WNT3 4085.0
H2BC13 4070.0
PSMB1 4033.0
PSMA5 4001.0
TLE3 3902.0
PSMD14 3838.0
H2AC7 3829.5
H2BC7 3829.5
CUL1 3754.0
BCL9 3721.0
H2BC6 3659.0
FZD5 3450.0
WNT8B 3241.0
WNT5B 3238.0
RSPO3 3216.0
CDC73 3203.0
RUVBL1 3185.0
WNT16 3163.0
ITPR2 3140.0
H2AC18 3107.5
H2AC19 3107.5
TERT 3095.0
PSMD12 3007.0
GNG3 2935.0
H4C16 2844.0
AP2S1 2832.0
SFRP1 2620.0
PSMA4 2616.0
WNT10A 2607.0
PYGO2 2582.0
PSME1 2536.0
DVL1 2494.0
SOX9 2446.0
LGR4 2389.0
AP2A1 2334.0
H4C1 2332.0
BTRC 2310.0
DVL3 2296.0
H3C11 2270.0
SOST 2219.0
SOX4 2163.0
TLE5 2125.0
PPP3R1 2053.0
H2AJ 2047.0
SMARCA4 1900.0
H3C6 1887.0
RPS27A 1837.0
PDE6B 1820.0
PPP2CA 1817.0
TNRC6A 1810.0
ITPR1 1737.0
DVL2 1626.0
GNG10 1595.0
NFATC1 1585.0
PPP3CA 1542.0
PYGO1 1390.0
H2BC4 1347.0
SOX2 1325.0
H3C2 1183.0
GSK3B 1036.0
ITPR3 994.0
H2AC6 949.0
WNT1 921.0
PSMD1 886.0
H2BC21 723.0
WNT7B 680.0
PSMD6 572.0
PSMC3 570.0
FZD3 546.0
PSMB2 533.0
VANGL2 513.0
PSMD8 460.0
RSPO4 423.0
PSMA3 337.0
PSMD5 170.0
TLE2 136.0
CUL3 113.0
PLCB3 56.0
EP300 15.0
H2BC5 -9.0
DAAM1 -95.0
RAC2 -151.0
PDE6G -232.0
CSNK1E -234.0
SNX3 -291.0
H3C4 -374.0
SEM1 -525.0
MAP3K7 -559.0
WNT2B -641.0
DKK2 -655.0
GNG7 -716.0
TLE4 -718.0
WNT9A -797.0
PSMA1 -810.0
TMED5 -860.0
MOV10 -904.0
USP34 -951.0
GNG4 -1001.0
H2BC10 -1032.0
PRKG1 -1101.0
KLHL12 -1125.0
CALM1 -1278.0
PPP2R1A -1400.0
H2BC15 -1414.0
WNT10B -1453.0
PFN1 -1458.0
CBY1 -1499.0
CSNK2A2 -1512.0
ARRB2 -1550.0
PRICKLE1 -1593.0
CXXC4 -1597.0
APC -1598.0
H2AX -1653.0
CSNK1A1 -1716.0
WNT6 -1752.0
GNB4 -1791.0
AGO4 -1920.0
GNG2 -2064.0
VPS29 -2168.0
PSME2 -2199.0
PSMD4 -2411.0
ROR2 -2446.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
RUNX3 -2818.0
FZD1 -2826.0
CAV1 -2895.0
H2BC3 -2958.0
PRKCG -2960.0
WNT7A -3003.0
ZNRF3 -3042.0
LGR5 -3061.0
RYK -3239.0
VPS26A -3423.0
H4C11 -3485.0
LRP6 -3493.0
TNKS2 -3536.0
LRP5 -3581.0
SCRIB -3776.0
WNT4 -3871.0
TCF4 -3909.0
GNB2 -4027.0
LEO1 -4029.0
PPP2R5E -4190.0
FRAT1 -4194.0
RSPO1 -4287.0
PSMB5 -4359.0
GNB1 -4430.0
TNRC6B -4433.0
GNG12 -4514.0
SMURF1 -4602.0
FZD6 -4650.0
MYC -4660.0
RHOA -4678.0
KRAS -4743.0
MEN1 -4780.0
PSMD3 -4790.0
PSMD2 -4823.0
TCF7L2 -4825.0
PSMA7 -4955.0
PSMA8 -4966.0
PSMB8 -5035.0
RSPO2 -5141.0
PIP5K1B -5180.0
HECW1 -5227.0
TCF7L1 -5388.0
PSMB9 -5459.0
PPP3CB -5477.0
WIF1 -5560.0
AGO3 -5584.0
AKT1 -5586.0
XPO1 -5699.0
PSMA6 -5784.0
PSMC2 -5834.0
DKK1 -5847.0
SOX6 -5870.0
PSMC4 -5874.0
H3C3 -5940.0
AXIN1 -6148.0
FZD7 -6331.0
H2BC1 -6416.0
GNGT2 -6419.0
WLS -6502.0
GNG5 -6508.0
CLTA -6520.0
UBB -6535.0
GNG13 -6611.0
KREMEN2 -6680.0
H2BC11 -6780.0
H2BC26 -6814.0
TLE1 -6861.0
PSMC1 -6897.0
H4C2 -7011.0
CSNK2A1 -7041.0
UBC -7308.0
H2AZ1 -7369.0
WNT3A -7414.0
PLCB1 -7468.0
PSME3 -7475.0
GNAO1 -7563.0
PSMB4 -7626.0
PSMC5 -7743.0
CTBP2 -7781.0
H3-3B -7982.0
KAT5 -8090.0
UBA52 -8101.0
PRKG2 -8265.0
RAC1 -8281.0
ROR1 -8299.0
SOX13 -8577.0
WNT8A -8693.0
RBBP5 -8717.0
H2AC8 -8778.0
FZD8 -8937.0
VPS35 -8949.0
LGR6 -9006.0
H2BC8 -9079.0
WNT9B -9439.0
DACT1 -9449.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
SKP1 -10072.0
PSMB10 -10166.0
WNT11 -10298.0
KREMEN1 -10750.0
PDE6A -10757.0
PPP2CB -10912.0
H3C12 -10932.0
FZD4 -10991.0
CAMK2A -11296.0
PSMB11 -11624.0


REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT
379
set REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT
setSize 222
pANOVA 0.00298
s.dist 0.116
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
DKK4 9504
H3C1 9085
H2AZ2 8952
AXIN2 8621
H2BC17 8591
H4C12 8556
PSMD13 8524
CTNNBIP1 8312
FRAT2 8272
PPP2R5D 8269
RNF146 8213
H4C5 8212
CREBBP 8084
LEF1 8081
SMURF2 8023
PPP2R5B 7999
KMT2D 7924
PPP2R1B 7726
PSMF1 7714
RBX1 7648

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DKK4 9504.0
H3C1 9085.0
H2AZ2 8952.0
AXIN2 8621.0
H2BC17 8591.0
H4C12 8556.0
PSMD13 8524.0
CTNNBIP1 8312.0
FRAT2 8272.0
PPP2R5D 8269.0
RNF146 8213.0
H4C5 8212.0
CREBBP 8084.0
LEF1 8081.0
SMURF2 8023.0
PPP2R5B 7999.0
KMT2D 7924.0
PPP2R1B 7726.0
PSMF1 7714.0
RBX1 7648.0
H3-4 7608.0
HDAC1 7322.0
PSMD11 7309.0
H2BC9 7299.5
H3C7 7299.5
TCF7 7254.0
PSME4 6905.0
PSMA2 6867.0
SOX17 6863.0
CHD8 6777.0
USP8 6699.0
PSMC6 6685.0
TNKS 6617.0
SOX7 6477.0
FZD2 6467.0
PSMB6 6285.0
BCL9L 6272.0
AKT2 6231.0
TRRAP 6116.0
H4C3 6009.0
H2BC12 5854.0
PPP2R5A 5717.0
H2AC4 5676.0
WNT5A 5593.0
H2AC20 5583.0
H3C8 5547.0
PSMD9 5439.0
CSNK2B 5425.0
RNF43 5405.0
H4C9 5306.0
SFRP2 5101.0
PSMD7 5071.0
CSNK1G2 5013.0
CTBP1 4983.0
ASH2L 4906.0
PSMB3 4905.0
PSMB7 4896.0
H4C6 4702.0
YWHAZ 4640.0
PPP2R5C 4507.0
CCDC88C 4236.0
H3-3A 4158.0
CTNNB1 4100.0
WNT3 4085.0
H2BC13 4070.0
PSMB1 4033.0
PSMA5 4001.0
TLE3 3902.0
PSMD14 3838.0
H2AC7 3829.5
H2BC7 3829.5
BCL9 3721.0
H2BC6 3659.0
FZD5 3450.0
WNT8B 3241.0
RSPO3 3216.0
CDC73 3203.0
RUVBL1 3185.0
H2AC18 3107.5
H2AC19 3107.5
TERT 3095.0
PSMD12 3007.0
H4C16 2844.0
SFRP1 2620.0
PSMA4 2616.0
PYGO2 2582.0
PSME1 2536.0
DVL1 2494.0
SOX9 2446.0
LGR4 2389.0
H4C1 2332.0
BTRC 2310.0
DVL3 2296.0
H3C11 2270.0
SOST 2219.0
SOX4 2163.0
H2AJ 2047.0
SMARCA4 1900.0
H3C6 1887.0
RPS27A 1837.0
PPP2CA 1817.0
DVL2 1626.0
PYGO1 1390.0
H2BC4 1347.0
SOX2 1325.0
H3C2 1183.0
GSK3B 1036.0
H2AC6 949.0
WNT1 921.0
PSMD1 886.0
H2BC21 723.0
PSMD6 572.0
PSMC3 570.0
PSMB2 533.0
PSMD8 460.0
RSPO4 423.0
PSMA3 337.0
PSMD5 170.0
TLE2 136.0
CUL3 113.0
EP300 15.0
H2BC5 -9.0
CSNK1E -234.0
H3C4 -374.0
SEM1 -525.0
DKK2 -655.0
TLE4 -718.0
WNT9A -797.0
PSMA1 -810.0
USP34 -951.0
H2BC10 -1032.0
KLHL12 -1125.0
PPP2R1A -1400.0
H2BC15 -1414.0
CBY1 -1499.0
CSNK2A2 -1512.0
CXXC4 -1597.0
APC -1598.0
H2AX -1653.0
CSNK1A1 -1716.0
PSME2 -2199.0
PSMD4 -2411.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
RUNX3 -2818.0
FZD1 -2826.0
CAV1 -2895.0
H2BC3 -2958.0
ZNRF3 -3042.0
LGR5 -3061.0
RYK -3239.0
H4C11 -3485.0
LRP6 -3493.0
TNKS2 -3536.0
LRP5 -3581.0
WNT4 -3871.0
TCF4 -3909.0
LEO1 -4029.0
PPP2R5E -4190.0
FRAT1 -4194.0
RSPO1 -4287.0
PSMB5 -4359.0
FZD6 -4650.0
MYC -4660.0
MEN1 -4780.0
PSMD3 -4790.0
PSMD2 -4823.0
TCF7L2 -4825.0
PSMA7 -4955.0
PSMA8 -4966.0
PSMB8 -5035.0
RSPO2 -5141.0
PIP5K1B -5180.0
HECW1 -5227.0
TCF7L1 -5388.0
PSMB9 -5459.0
WIF1 -5560.0
AKT1 -5586.0
XPO1 -5699.0
PSMA6 -5784.0
PSMC2 -5834.0
DKK1 -5847.0
SOX6 -5870.0
PSMC4 -5874.0
H3C3 -5940.0
AXIN1 -6148.0
H2BC1 -6416.0
UBB -6535.0
KREMEN2 -6680.0
H2BC11 -6780.0
H2BC26 -6814.0
TLE1 -6861.0
PSMC1 -6897.0
H4C2 -7011.0
CSNK2A1 -7041.0
UBC -7308.0
H2AZ1 -7369.0
WNT3A -7414.0
PSME3 -7475.0
PSMB4 -7626.0
PSMC5 -7743.0
H3-3B -7982.0
KAT5 -8090.0
UBA52 -8101.0
SOX13 -8577.0
WNT8A -8693.0
RBBP5 -8717.0
H2AC8 -8778.0
FZD8 -8937.0
LGR6 -9006.0
H2BC8 -9079.0
DACT1 -9449.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
PSMB10 -10166.0
KREMEN1 -10750.0
PPP2CB -10912.0
H3C12 -10932.0
FZD4 -10991.0
PSMB11 -11624.0


REACTOME_SENSORY_PROCESSING_OF_SOUND

REACTOME_SENSORY_PROCESSING_OF_SOUND
1510
set REACTOME_SENSORY_PROCESSING_OF_SOUND
setSize 72
pANOVA 0.00315
s.dist -0.201
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC17A8 -11148
USH1C -11018
STRC -10961
ACTB -10333
EPS8L2 -10129
EPB41L1 -10094
LRRC52 -9867
CACNA2D2 -9629
BSN -9492
RAB3A -9326
TMC2 -8826
CLIC5 -8805
FSCN2 -8771
CHRNA9 -8675
STX1A -8545
OTOG -8474
EPB41L3 -8462
CACNA1D -8381
ACTG1 -8054
KCNMA1 -7872

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC17A8 -11148
USH1C -11018
STRC -10961
ACTB -10333
EPS8L2 -10129
EPB41L1 -10094
LRRC52 -9867
CACNA2D2 -9629
BSN -9492
RAB3A -9326
TMC2 -8826
CLIC5 -8805
FSCN2 -8771
CHRNA9 -8675
STX1A -8545
OTOG -8474
EPB41L3 -8462
CACNA1D -8381
ACTG1 -8054
KCNMA1 -7872
OTOF -7829
CTBP2 -7781
CDH23 -7423
TMIE -7197
XIRP2 -7108
CAPZA2 -6878
KCNN2 -6029
ESPNL -5465
EPS8 -5326
KCNQ4 -5051
RDX -4606
ATP2B1 -4576
TRIOBP -4299
ATP2B2 -4206
USH1G -4174
CAPZA1 -3984
MYH9 -3268
SPTAN1 -3189
MYO3A -2539
PJVK -2268
MYO3B -2181
GRXCR1 -1984
PCLO -1899
OTOGL -1817
TWF2 -1680
PLS1 -1346
GRXCR2 -1244
CABP1 -1228
PCDH15 -1159
MYO7A -1144
MYO15A -883
GSN -546
MYO1C -537
CABP2 37
CAPZB 419
EZR 432
WHRN 735
TMC1 811
CACNB2 1675
SPTBN1 1819
ESPN 2467
VAMP2 2995
SNAP25 3092
TPRN 3570
TWF1 4211
SLC26A5 4317
LHFPL5 4340
CHRNA10 6052
DNAJC5 6484
KCNMB1 6660
RIPOR2 7014
CIB2 8580


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 0.00321
s.dist -0.123
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
RRP36 -11774.0
RPL29 -11475.0
UTP11 -11195.0
RPL18 -11061.0
RPLP2 -11033.0
NOP56 -10871.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
NOL12 -10061.0
RPL36 -10058.0
PNO1 -10025.0
RPS28 -9918.0
RPL4 -9917.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RRP36 -11774.0
RPL29 -11475.0
UTP11 -11195.0
RPL18 -11061.0
RPLP2 -11033.0
NOP56 -10871.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
RPL10A -10119.0
NOL12 -10061.0
RPL36 -10058.0
PNO1 -10025.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
NAT10 -9609.0
RRP9 -9507.0
BYSL -9419.0
RPL37 -9383.0
RPL38 -9338.0
MTERF4 -9286.0
RPL18A -9270.0
RRP1 -9191.0
GAR1 -9166.0
RPL14 -9085.0
ERI1 -9076.0
WDR3 -8988.0
DDX21 -8951.0
RPP38 -8790.0
XRN2 -8656.0
DDX49 -8638.0
EXOSC9 -8598.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
BMS1 -7981.0
RPP40 -7831.0
RPL35A -7809.0
FTSJ3 -7765.0
RPS25 -7758.0
UTP18 -7735.0
WDR12 -7547.0
WDR36 -7325.0
NCL -7281.0
RPS5 -7280.0
RIOK2 -7205.0
RPS13 -7029.0
RPS6 -6939.0
RPL13 -6617.0
PDCD11 -6465.0
NOP14 -6447.0
RPS20 -6260.0
EBNA1BP2 -6106.0
HEATR1 -5797.0
RPL41 -5634.0
MPHOSPH6 -5603.0
RPS21 -5458.0
DCAF13 -5367.0
RPL23A -5311.0
RPS24 -5072.0
NOL9 -5024.0
RPL39L -5003.0
NSUN4 -4803.0
RPL22L1 -4795.0
DIMT1 -4752.0
NOC4L -4741.0
RPS23 -4737.0
RPL7A -4508.0
WDR75 -4486.0
ISG20L2 -4479.0
SNU13 -4177.0
RCL1 -4156.0
TSR1 -4082.0
NIP7 -4063.0
RPL3L -4049.0
RPL6 -4047.0
EXOSC7 -3960.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
IMP4 -3703.0
DIS3 -3636.0
NOB1 -3517.0
RPL30 -3513.0
MRM3 -3417.0
PELP1 -3264.0
NOP58 -3224.0
RPL35 -3180.0
RPL24 -2999.0
LTV1 -2978.0
EXOSC5 -2935.0
RPS7 -2847.0
TSR3 -2821.0
RPSA -2801.0
MTREX -2778.0
PES1 -2677.0
EXOSC8 -2523.0
RPL9 -2423.0
UTP20 -2371.0
RPS27L -2334.0
RPS26 -2128.0
RPL28 -2101.0
RPP30 -1866.0
RPS3 -1606.0
FBL -1591.0
UTP15 -1520.0
UTP4 -1447.0
NOP2 -1293.0
RPL22 -1193.0
RPS29 -1088.0
RPL17 -837.0
TFB1M -774.0
RPL5 -544.0
IMP3 -524.0
PRORP -513.0
WDR46 -432.0
EXOSC10 -311.0
CSNK1E -234.0
RPS11 -225.0
KRR1 -134.0
RPL26 -28.0
RPL27A 454.0
DDX47 947.0
RPL19 1027.0
RPL11 1163.0
WDR43 1168.0
RPS16 1311.0
UTP25 1351.0
RPS27A 1837.0
GNL3 1999.0
EXOSC4 2195.0
NOL11 2484.0
C1D 2834.0
RPLP1 2863.0
BUD23 2970.0
TRMT112 3158.0
FCF1 3478.0
BOP1 3631.0
UTP3 3661.0
EXOSC1 3720.0
RPP21 3827.0
RPL34 3847.0
NOP10 3898.0
TEX10 4031.0
NOL6 4051.0
TRMT10C 4103.0
PWP2 4238.0
CSNK1D 4310.0
RPS9 4427.0
EMG1 4654.0
RPL37A 4707.0
RIOK1 4804.0
UTP6 4862.0
EXOSC3 5028.0
THUMPD1 5034.0
MRM2 5217.0
RPL15 5290.0
DDX52 5482.0
NHP2 5708.0
RPL26L1 5864.0
TBL3 5961.0
WDR18 6277.0
MRM1 6300.0
RPP14 6735.0
RIOK3 7007.0
RPL32 7009.0
MPHOSPH10 7021.0
RPS19 7158.0
RBM28 7607.0
RPS27 7711.0
ELAC2 7800.0
RPS14 8094.0
UTP14C 8235.0
RPL31 8401.0
RPP25 8520.0
DHX37 8624.0
SENP3 9092.0
EXOSC2 9111.0
RPL10L 9197.0
RRP7A 9308.0
EXOSC6 9622.0


REACTOME_PTEN_REGULATION

REACTOME_PTEN_REGULATION
1079
set REACTOME_PTEN_REGULATION
setSize 135
pANOVA 0.00329
s.dist 0.147
p.adjustANOVA 0.193



Top enriched genes

Top 20 genes
GeneID Gene Rank
SUZ12 9441
AGO1 9194
BMI1 9147
PSMD13 8524
RNF146 8213
LAMTOR3 8110
MTA3 8017
PSMF1 7714
HDAC1 7322
PSMD11 7309
MTOR 7178
MKRN1 7135
HDAC3 7126
LAMTOR4 7004
PPARG 6934
PSME4 6905
PSMA2 6867
OTUD3 6737
TNRC6C 6711
PSMC6 6685

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SUZ12 9441
AGO1 9194
BMI1 9147
PSMD13 8524
RNF146 8213
LAMTOR3 8110
MTA3 8017
PSMF1 7714
HDAC1 7322
PSMD11 7309
MTOR 7178
MKRN1 7135
HDAC3 7126
LAMTOR4 7004
PPARG 6934
PSME4 6905
PSMA2 6867
OTUD3 6737
TNRC6C 6711
PSMC6 6685
TNKS 6617
CBX2 6305
PSMB6 6285
AKT2 6231
LAMTOR1 6216
WWP2 6139
EZH2 5620
NR2E1 5474
PSMD9 5439
CSNK2B 5425
RPTOR 5338
SNAI1 5300
PSMD7 5071
NEDD4 4997
PSMB3 4905
PSMB7 4896
AGO2 4867
PHC3 4830
REST 4325
AKT3 4319
PSMB1 4033
PSMA5 4001
PSMD14 3838
PREX2 3744
SCMH1 3707
HDAC2 3563
KDM1A 3304
MTA1 3198
EED 3060
PSMD12 3007
MECOM 2999
PSMA4 2616
PSME1 2536
HDAC7 2503
USP13 2456
LAMTOR2 2452
CBX4 2447
PML 2311
TRIM27 2257
CHD3 1941
RPS27A 1837
TNRC6A 1810
RNF2 1715
LAMTOR5 1572
MBD3 1368
PSMD1 886
MAPK3 866
PSMD6 572
PSMC3 570
SALL4 567
PSMB2 533
GATAD2B 485
PSMD8 460
PSMA3 337
PHC1 323
RRAGA 215
PSMD5 170
CHD4 -106
RRAGD -286
ATN1 -480
SEM1 -525
PSMA1 -810
MOV10 -904
RCOR1 -997
FRK -1029
CSNK2A2 -1512
CBX8 -1633
RBBP4 -1649
RING1 -1753
GATAD2A -1886
AGO4 -1920
RRAGC -2136
PSME2 -2199
PSMD4 -2411
SLC38A9 -2609
PHC2 -2666
JUN -2983
TNKS2 -3536
EGR1 -3639
MAPK1 -3902
RHEB -4109
HDAC5 -4266
PSMB5 -4359
TNRC6B -4433
PSMD3 -4790
PSMD2 -4823
PSMA7 -4955
PSMA8 -4966
PSMB8 -5035
PSMB9 -5459
AGO3 -5584
AKT1 -5586
ATF2 -5645
PTEN -5671
PSMA6 -5784
STUB1 -5809
PSMC2 -5834
PSMC4 -5874
CBX6 -6482
UBB -6535
PSMC1 -6897
CSNK2A1 -7041
UBC -7308
PSME3 -7475
PSMB4 -7626
PSMC5 -7743
UBA52 -8101
MAF1 -8253
MLST8 -8255
TP53 -8352
MTA2 -9053
USP7 -9538
SNAI2 -9618
PSMB10 -10166
PSMB11 -11624


REACTOME_ANTIMICROBIAL_PEPTIDES

REACTOME_ANTIMICROBIAL_PEPTIDES
1060
set REACTOME_ANTIMICROBIAL_PEPTIDES
setSize 76
pANOVA 0.00359
s.dist -0.193
p.adjustANOVA 0.2



Top enriched genes

Top 20 genes
GeneID Gene Rank
S100A7 -12023
REG3G -11951
GNLY -11925
DEFB136 -11786
RNASE8 -11750
CCR6 -11704
LCN2 -11573
PLA2G2A -11543
DEFA4 -11520
DEFB134 -11493
DEFB133 -11384
EPPIN-WFDC6 -11258
CAMP -11151
SEMG1 -10783
S100A8 -10656
RNASE7 -10588
DEFB123 -10545
DEFB124 -10449
S100A7A -10249
PGLYRP3 -9862

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
S100A7 -12023.0
REG3G -11951.0
GNLY -11925.0
DEFB136 -11786.0
RNASE8 -11750.0
CCR6 -11704.0
LCN2 -11573.0
PLA2G2A -11543.0
DEFA4 -11520.0
DEFB134 -11493.0
DEFB133 -11384.0
EPPIN-WFDC6 -11258.0
CAMP -11151.0
SEMG1 -10783.0
S100A8 -10656.0
RNASE7 -10588.0
DEFB123 -10545.0
DEFB124 -10449.0
S100A7A -10249.0
PGLYRP3 -9862.0
BPIFB6 -9664.0
HTN3 -9233.0
HTN1 -8781.0
PRSS3 -8769.0
ELANE -8725.0
EPPIN -8450.0
PRTN3 -8300.0
BPIFA1 -8196.0
DCD -8008.0
BPIFA2 -8004.0
LEAP2 -7805.0
BPIFB4 -6970.0
DEFB110 -6890.0
CD4 -6717.0
LTF -6556.0
CHGA -6143.0
SLC11A1 -5966.0
BPIFB1 -5358.0
PI3 -5031.0
DEFB104A -4998.5
DEFB104B -4998.5
DEFB113 -4571.0
BPIFB2 -4519.0
CTSG -3799.0
DEFB127 -3698.0
DEFB135 -3441.0
DEFB1 -3192.0
ART1 -2686.0
DEFB118 -1428.0
TLR1 -1161.0
DEFB132 -834.0
RNASE3 961.0
DEFB128 1075.0
TLR2 2095.0
REG3A 2417.0
DEFB125 2820.0
BPI 3655.0
ATOX1 3814.0
DEFB121 4604.0
PGLYRP4 5574.0
DEFA5 5874.0
CLU 6544.0
DEFB126 6845.0
CCR2 7161.0
DEFB116 7675.0
RNASE6 7720.0
LYZ 8043.0
S100A9 8281.0
DEFB115 8330.0
DEFB129 8798.0
DEFB119 9037.0
PGLYRP1 9261.0
DEFB114 9294.0
PGLYRP2 9325.0
DEFA6 9489.0
ITLN1 9674.0


REACTOME_MUSCLE_CONTRACTION

REACTOME_MUSCLE_CONTRACTION
674
set REACTOME_MUSCLE_CONTRACTION
setSize 197
pANOVA 0.00372
s.dist -0.12
p.adjustANOVA 0.2



Top enriched genes

Top 20 genes
GeneID Gene Rank
SCN11A -11930
MYL4 -11898
ATP1A2 -11897
FXYD4 -11708
KCNK18 -11638
MYL7 -11545
KCNK7 -11525
MYL10 -11312
CAMK2A -11296
MYH6 -11145
CACNG4 -11020
FXYD2 -10790
MYH8 -10729
TNNI1 -10691
MYL3 -10571
KCNE1 -10429
MYLK -10393
NPPA -10027
SCN5A -9911
SCN3A -9865

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SCN11A -11930
MYL4 -11898
ATP1A2 -11897
FXYD4 -11708
KCNK18 -11638
MYL7 -11545
KCNK7 -11525
MYL10 -11312
CAMK2A -11296
MYH6 -11145
CACNG4 -11020
FXYD2 -10790
MYH8 -10729
TNNI1 -10691
MYL3 -10571
KCNE1 -10429
MYLK -10393
NPPA -10027
SCN5A -9911
SCN3A -9865
TRPC1 -9856
CACNA1C -9846
TNNT3 -9806
KCND3 -9721
CACNA2D2 -9629
KCNJ4 -9509
ITGB5 -9313
SCN2A -9149
DYSF -9070
KCNK17 -9020
TNNT2 -8979
KCNK5 -8833
KCNE4 -8532
CES1 -8497
MYL2 -8427
CASQ2 -8424
SCN8A -8413
CASQ1 -8209
MYL5 -8173
SCN7A -8153
CAMK2B -8137
NPR1 -7919
KCNK15 -7839
TPM2 -7696
ACTG2 -7658
ACTN2 -7595
TNNC1 -7518
SORBS1 -7401
CACNG6 -7311
SCN2B -7285
KCNIP3 -7231
KCNK1 -7229
PRKACA -7200
DES -7125
KCNK4 -7116
ORAI1 -7107
ABCC9 -7097
TNNC2 -7092
CACNA1G -6895
KCNK9 -6849
ACTN3 -6678
ATP1B3 -6629
SLC8A2 -6623
KCNJ12 -6592
FKBP1B -6430
FXYD3 -6379
MYL12A -6263
SLC8A3 -5878
KCNJ2 -5795
CORIN -5673
ATP1A1 -5568
MYL9 -5545
SCN1A -5526
SLC8A1 -5393
FGF14 -5177
ACTC1 -5125
ACTA2 -5015
WWTR1 -4896
ITGA1 -4865
ATP1B2 -4787
TPM4 -4604
SRI -4582
ATP2B1 -4576
CALD1 -4547
AHCYL1 -4527
PDE5A -4417
TRDN -4316
ALDH2 -4221
ATP2B2 -4206
MME -4127
CACNA1I -3561
ATP1A4 -3558
RANGRF -3519
NOS1 -3498
RYR2 -3257
VIM -2800
KAT2B -2785
MYL1 -2734
SCN1B -2616
TNNI2 -2453
SCN9A -2207
ACTA1 -2172
SCN4B -2060
PAK1 -1880
KCNQ1 -1549
GUCY1A1 -1519
CALM1 -1278
CACNA1H -1246
KCNIP1 -1194
NKX2-5 -1189
CAMK2G -1167
AKAP9 -1063
ORAI2 -1035
KCNK12 -1022
TMOD4 -949
HIPK2 -843
KCNJ14 -790
TMOD3 -767
LMOD1 -757
ASPH -712
RYR3 -707
TMOD2 -581
KCNK3 -575
TMOD1 -470
ATP1B1 -403
KCNE2 -387
FXYD1 -152
ATP2B4 -44
CAMK2D -17
STIM1 -10
MYBPC1 61
KCNK13 273
KCND2 274
RYR1 428
SLN 819
MYH11 837
PLN 966
ITPR3 994
FXYD7 1295
KCNIP2 1365
KCNK10 1422
GATA4 1616
CACNB2 1675
DMPK 1732
ITPR1 1737
KCNIP4 1765
VCL 1920
KCNK16 2073
GUCY1A2 2233
SCN4A 2418
NPR2 2694
ITPR2 3140
MYL12B 3166
FGF12 3316
FXYD6 3398
NEB 3519
CACNG7 3574
CACNB1 3619
SCN3B 3645
CACNG8 3674
SCN10A 3702
TPM1 3759
SORBS3 3856
CAV3 4037
MYBPC2 4392
PXN 4403
ATP2A1 4410
NPPC 4476
TNNI3 4493
PAK2 4670
MYL11 4716
TLN1 5042
ANXA1 5126
TBX5 5132
ATP2A3 5521
KCNH2 5534
GUCY1B1 5599
TRIM72 5611
ANXA2 5649
KCNJ11 5678
KCNK2 5851
TTN 6724
ATP2A2 6733
TNNT1 6872
TCAP 6895
FGF11 6949
KCNK6 6960
ANXA6 6986
ATP1A3 7187
MYBPC3 7262
MYL6B 7473
TPM3 7658
KCNE3 7681
HIPK1 8029
MYH3 8227
MYL6 8862
KCNA5 9034


REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE

REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE
521
set REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE
setSize 5
pANOVA 0.00378
s.dist -0.748
p.adjustANOVA 0.2



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
MASP1 -10383
FCN3 -10157
MASP2 -3170

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
MASP1 -10383
FCN3 -10157
MASP2 -3170


REACTOME_CARDIAC_CONDUCTION

REACTOME_CARDIAC_CONDUCTION
883
set REACTOME_CARDIAC_CONDUCTION
setSize 125
pANOVA 0.00436
s.dist -0.148
p.adjustANOVA 0.223



Top enriched genes

Top 20 genes
GeneID Gene Rank
SCN11A -11930
ATP1A2 -11897
FXYD4 -11708
KCNK18 -11638
KCNK7 -11525
CAMK2A -11296
CACNG4 -11020
FXYD2 -10790
KCNE1 -10429
NPPA -10027
SCN5A -9911
SCN3A -9865
TRPC1 -9856
CACNA1C -9846
KCND3 -9721
CACNA2D2 -9629
KCNJ4 -9509
SCN2A -9149
KCNK17 -9020
KCNK5 -8833

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SCN11A -11930
ATP1A2 -11897
FXYD4 -11708
KCNK18 -11638
KCNK7 -11525
CAMK2A -11296
CACNG4 -11020
FXYD2 -10790
KCNE1 -10429
NPPA -10027
SCN5A -9911
SCN3A -9865
TRPC1 -9856
CACNA1C -9846
KCND3 -9721
CACNA2D2 -9629
KCNJ4 -9509
SCN2A -9149
KCNK17 -9020
KCNK5 -8833
KCNE4 -8532
CES1 -8497
CASQ2 -8424
SCN8A -8413
CASQ1 -8209
SCN7A -8153
CAMK2B -8137
NPR1 -7919
KCNK15 -7839
CACNG6 -7311
SCN2B -7285
KCNIP3 -7231
KCNK1 -7229
PRKACA -7200
KCNK4 -7116
ORAI1 -7107
ABCC9 -7097
KCNK9 -6849
ATP1B3 -6629
SLC8A2 -6623
KCNJ12 -6592
FKBP1B -6430
FXYD3 -6379
SLC8A3 -5878
KCNJ2 -5795
CORIN -5673
ATP1A1 -5568
SCN1A -5526
SLC8A1 -5393
FGF14 -5177
WWTR1 -4896
ATP1B2 -4787
SRI -4582
ATP2B1 -4576
AHCYL1 -4527
TRDN -4316
ATP2B2 -4206
MME -4127
ATP1A4 -3558
RANGRF -3519
NOS1 -3498
RYR2 -3257
KAT2B -2785
SCN1B -2616
SCN9A -2207
SCN4B -2060
KCNQ1 -1549
CALM1 -1278
KCNIP1 -1194
NKX2-5 -1189
CAMK2G -1167
AKAP9 -1063
ORAI2 -1035
KCNK12 -1022
HIPK2 -843
KCNJ14 -790
ASPH -712
RYR3 -707
KCNK3 -575
ATP1B1 -403
KCNE2 -387
FXYD1 -152
ATP2B4 -44
CAMK2D -17
STIM1 -10
KCNK13 273
KCND2 274
RYR1 428
SLN 819
PLN 966
ITPR3 994
FXYD7 1295
KCNIP2 1365
KCNK10 1422
GATA4 1616
CACNB2 1675
DMPK 1732
ITPR1 1737
KCNIP4 1765
KCNK16 2073
SCN4A 2418
NPR2 2694
ITPR2 3140
FGF12 3316
FXYD6 3398
CACNG7 3574
CACNB1 3619
SCN3B 3645
CACNG8 3674
SCN10A 3702
ATP2A1 4410
NPPC 4476
TNNI3 4493
TBX5 5132
ATP2A3 5521
KCNH2 5534
KCNJ11 5678
KCNK2 5851
ATP2A2 6733
FGF11 6949
KCNK6 6960
ATP1A3 7187
KCNE3 7681
HIPK1 8029
KCNA5 9034


REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS

REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS
1428
set REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS
setSize 21
pANOVA 0.0046
s.dist -0.357
p.adjustANOVA 0.229



Top enriched genes

Top 20 genes
GeneID Gene Rank
FUT3 -12042
FUT7 -11738
B3GALT4 -11550
FUT5 -10530
FUT1 -9646
ST3GAL6 -8873
RHCE -8277
ST6GALNAC6 -7158
FUT10 -6770
B3GALT5 -6361
FUT11 -6131
B3GALT1 -5942
FUT9 -5773
FUT2 -5106
B3GALT2 -3993
FUT6 -3099
RHD -722
B4GALNT2 2822
ST3GAL4 2829
ST3GAL3 3301

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FUT3 -12042
FUT7 -11738
B3GALT4 -11550
FUT5 -10530
FUT1 -9646
ST3GAL6 -8873
RHCE -8277
ST6GALNAC6 -7158
FUT10 -6770
B3GALT5 -6361
FUT11 -6131
B3GALT1 -5942
FUT9 -5773
FUT2 -5106
B3GALT2 -3993
FUT6 -3099
RHD -722
B4GALNT2 2822
ST3GAL4 2829
ST3GAL3 3301
FUT4 8064


REACTOME_HATS_ACETYLATE_HISTONES

REACTOME_HATS_ACETYLATE_HISTONES
551
set REACTOME_HATS_ACETYLATE_HISTONES
setSize 129
pANOVA 0.00518
s.dist 0.143
p.adjustANOVA 0.244



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATXN7L3 9351.0
H3C1 9085.0
ING5 8712.0
H2AC17 8661.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
PHF20 8130.0
CREBBP 8084.0
VPS72 7853.0
MEAF6 7374.0
H2BC9 7299.5
H3C7 7299.5
BRPF3 7223.0
KAT6B 7176.0
KAT2A 6840.0
PAX3 6359.0
SGF29 6237.0
SUPT3H 6214.0
TRRAP 6116.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATXN7L3 9351.0
H3C1 9085.0
ING5 8712.0
H2AC17 8661.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
PHF20 8130.0
CREBBP 8084.0
VPS72 7853.0
MEAF6 7374.0
H2BC9 7299.5
H3C7 7299.5
BRPF3 7223.0
KAT6B 7176.0
KAT2A 6840.0
PAX3 6359.0
SGF29 6237.0
SUPT3H 6214.0
TRRAP 6116.0
USP22 6064.0
H4C3 6009.0
YEATS4 5980.0
YEATS2 5951.0
H2BC12 5854.0
H2AC4 5676.0
H2AC20 5583.0
H3C8 5547.0
H4C9 5306.0
WDR5 5255.0
BRPF1 5199.0
KAT7 4759.0
H4C6 4702.0
EP400 4349.0
MRGBP 4243.0
ATXN7 4231.0
CLOCK 4129.0
TAF12 4104.0
KAT6A 4096.0
H2BC13 4070.0
TADA2B 4019.0
H2AC7 3829.5
H2BC7 3829.5
JADE1 3796.0
ELP5 3676.0
ENY2 3670.0
H2BC6 3659.0
SUPT7L 3557.0
ELP1 3305.0
BRD1 3193.0
RUVBL1 3185.0
TAF9 3178.0
H2AC18 3107.5
H2AC19 3107.5
MCRS1 2987.0
H4C16 2844.0
H4C1 2332.0
MSL2 2291.0
H3C11 2270.0
H3C6 1887.0
H2BC4 1347.0
H3C2 1183.0
TAF6L 951.0
H2AC6 949.0
JADE2 814.0
KANSL1 785.0
H2BC21 723.0
H2AC11 355.0
H2AC12 334.0
EP300 15.0
H2BC5 -9.0
ELP2 -36.0
ELP4 -179.0
SAP130 -255.0
H3C4 -374.0
TADA1 -394.0
H2AC13 -397.0
H2BC10 -1032.0
H2AC21 -1383.0
H2BC15 -1414.0
NCOA2 -1529.0
DR1 -1989.0
TADA3 -2200.0
ACTL6A -2279.0
TAF10 -2376.0
H2AC15 -2567.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
HAT1 -2766.0
DMAP1 -2767.0
KAT2B -2785.0
H2BC3 -2958.0
TADA2A -3340.0
MBIP -3343.0
H4C11 -3485.0
ING4 -3590.0
TAF5L -3661.0
ELP6 -4097.0
KANSL2 -4640.0
NCOA1 -4726.0
MSL1 -4765.0
H2AC25 -4996.0
MORF4L1 -5191.0
BRD8 -5265.0
ING3 -5605.0
ATF2 -5645.0
EPC1 -5791.0
H3C3 -5940.0
SUPT20H -5960.0
KAT8 -6007.0
ZZZ3 -6170.0
H2AC1 -6184.0
H2BC1 -6416.0
H2BC11 -6780.0
H2BC26 -6814.0
H4C2 -7011.0
RUVBL2 -7262.0
H2AC16 -7951.0
KAT5 -8090.0
ELP3 -8315.0
H2AC8 -8778.0
H2BC8 -9079.0
KANSL3 -9475.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
ACTB -10333.0
H3C12 -10932.0


REACTOME_RHO_GTPASE_EFFECTORS

REACTOME_RHO_GTPASE_EFFECTORS
342
set REACTOME_RHO_GTPASE_EFFECTORS
setSize 305
pANOVA 0.0052
s.dist 0.093
p.adjustANOVA 0.244



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C1 9085
H2AZ2 8952
MYL6 8862
GOPC 8827
TUBA3C 8794
SCAI 8780
MAPRE1 8713
KNTC1 8636
TUBB1 8617
H2BC17 8591
H4C12 8556
PPP1R14A 8437
S100A9 8281
PPP2R5D 8269
H4C5 8212
CLIP1 8150
CLASP2 8135
PPP2R5B 7999
RHOB 7922
TAOK1 7879

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C1 9085.0
H2AZ2 8952.0
MYL6 8862.0
GOPC 8827.0
TUBA3C 8794.0
SCAI 8780.0
MAPRE1 8713.0
KNTC1 8636.0
TUBB1 8617.0
H2BC17 8591.0
H4C12 8556.0
PPP1R14A 8437.0
S100A9 8281.0
PPP2R5D 8269.0
H4C5 8212.0
CLIP1 8150.0
CLASP2 8135.0
PPP2R5B 7999.0
RHOB 7922.0
TAOK1 7879.0
CENPO 7809.0
MAD1L1 7744.0
PPP2R1B 7726.0
RPS27 7711.0
MAPK14 7626.0
CTTN 7494.0
PDPK1 7458.0
NCKIPSD 7406.0
H2BC9 7299.5
H3C7 7299.5
B9D2 7287.0
LIMK2 7205.0
SEH1L 7023.0
TAX1BP3 6990.0
SRGAP2 6853.0
EVL 6783.0
DYNC1LI1 6729.0
DYNC1H1 6601.0
ARPC1A 6552.0
SPC24 6531.0
AURKB 6511.0
RHOQ 6464.0
ABI2 6438.0
CENPF 6418.0
RHOD 6391.0
INCENP 6349.0
PRKCZ 6322.0
WASF1 6194.0
H4C3 6009.0
NDEL1 5866.0
H2BC12 5854.0
DIAPH3 5748.0
PPP2R5A 5717.0
H2AC4 5676.0
H2AC20 5583.0
TUBA4A 5555.0
H3C8 5547.0
MAPK11 5430.0
NOXA1 5340.0
H4C9 5306.0
PRKCB 4990.0
PRKCA 4876.0
NUP98 4773.0
CENPE 4766.0
NCKAP1 4739.0
H4C6 4702.0
PAK2 4670.0
YWHAZ 4640.0
ARPC3 4577.0
WIPF2 4509.0
PPP2R5C 4507.0
CDC42 4492.0
KIF2C 4469.0
BRK1 4435.0
ABI1 4400.0
KNL1 4393.0
KLC3 4365.0
ROCK2 4363.0
KTN1 4356.0
NUP160 4345.0
RTKN 4322.0
KIF18A 4221.0
H3-3A 4158.0
CTNNB1 4100.0
H2BC13 4070.0
NDE1 4024.0
DIAPH1 3961.0
NUF2 3895.0
ABL1 3849.0
H2AC7 3829.5
H2BC7 3829.5
PRC1 3826.0
TUBB8 3806.0
CENPK 3678.0
H2BC6 3659.0
TUBB4A 3526.0
TUBA4B 3468.0
CENPN 3409.0
CKAP5 3390.0
RCC2 3360.0
TUBB4B 3352.0
PPP1R12B 3314.0
CYFIP2 3311.0
KDM1A 3304.0
MYL12B 3166.0
BIRC5 3110.0
H2AC18 3107.5
H2AC19 3107.5
BUB1B 3099.0
FMNL3 3079.0
ROPN1 3056.0
DYNC1I2 3054.0
NUP37 3040.0
H4C16 2844.0
BUB3 2757.0
DVL1 2494.0
KLC1 2423.0
ARPC5 2343.0
CENPU 2336.0
H4C1 2332.0
KIF14 2321.0
DVL3 2296.0
SGO2 2287.0
H3C11 2270.0
IQGAP1 2259.0
H2AJ 2047.0
CTNNA1 2009.0
PKN3 1956.0
SEC13 1952.0
H3C6 1887.0
PPP2CA 1817.0
CENPA 1710.0
PRKCD 1634.0
DVL2 1626.0
NUP107 1476.0
PFN2 1443.0
H2BC4 1347.0
GRB2 1328.0
KDM4C 1298.0
CENPH 1223.0
H3C2 1183.0
NCKAP1L 1154.0
CLASP1 1102.0
MAD2L1 1096.0
IQGAP2 1060.0
TUBB3 1052.0
H2AC6 949.0
CIT 929.0
MAPK3 866.0
MYH11 837.0
BUB1 812.0
CDC25C 737.0
H2BC21 723.0
SRC 550.0
AHCTF1 452.0
MRTFA 400.0
YWHAG 201.0
PKN2 94.0
H2BC5 -9.0
CENPT -26.0
DAAM1 -95.0
RAC2 -151.0
H3C4 -374.0
PPP1CB -384.0
DYNC1I1 -433.0
TUBB2B -595.0
KIF5B -945.0
ZWILCH -1021.0
H2BC10 -1032.0
RANGAP1 -1150.0
PIK3C3 -1205.0
CALM1 -1278.0
NSL1 -1316.0
PPP2R1A -1400.0
H2BC15 -1414.0
PFN1 -1458.0
WASL -1503.0
NCOA2 -1529.0
NUDC -1543.0
H2AX -1653.0
NDC80 -1672.0
NCF2 -1761.0
PAK1 -1880.0
ACTR3 -1930.0
ARPC2 -2180.0
PIK3R4 -2201.0
ZWINT -2209.0
PAFAH1B1 -2384.0
CDCA8 -2485.0
LIMK1 -2563.0
MIS12 -2586.0
WASF2 -2615.0
YWHAE -2626.0
H4C13 -2630.0
H4C4 -2649.0
NF2 -2664.0
FMNL1 -2681.0
H4C8 -2728.0
TUBA1C -2761.0
ZW10 -2773.0
CDKN1B -2790.0
H2BC3 -2958.0
RANBP2 -2965.0
NUP133 -2987.0
TUBB6 -3105.0
DYNLL1 -3248.0
RHOG -3249.0
MYH9 -3268.0
WIPF1 -3304.0
ROCK1 -3317.0
RHOC -3370.0
NCK1 -3408.0
SPDL1 -3435.0
PPP1R12A -3452.0
H4C11 -3485.0
ARPC4 -3605.0
MYH10 -3625.0
ITGB3BP -3696.0
IQGAP3 -3731.0
MAPK1 -3902.0
CENPS -3932.0
CFTR -3968.0
TUBA1B -3969.0
KLK3 -4180.0
PTK2 -4183.0
PPP2R5E -4190.0
DYNC1LI2 -4243.0
BAIAP2 -4376.0
NOXO1 -4611.0
RHOA -4678.0
MEN1 -4780.0
CFL1 -4810.0
PLK1 -4822.0
YWHAQ -4844.0
KLC2 -5044.0
TUBAL3 -5273.0
YWHAH -5306.0
TUBA1A -5328.0
PKN1 -5454.0
CENPC -5501.0
SKA2 -5511.0
MYL9 -5545.0
CYFIP1 -5596.0
WASF3 -5670.0
XPO1 -5699.0
SRF -5706.0
DLG4 -5765.0
NOX3 -5930.0
H3C3 -5940.0
RHPN1 -6333.0
CENPL -6355.0
TUBB2A -6393.0
H2BC1 -6416.0
YWHAB -6461.0
PIN1 -6552.0
WIPF3 -6615.0
LIN7B -6716.0
CYBA -6734.0
H2BC11 -6780.0
H2BC26 -6814.0
SPC25 -6926.0
MYH14 -6999.0
H4C2 -7011.0
CENPP -7022.0
RHPN2 -7061.0
CENPQ -7094.0
KIF2B -7248.0
KIF2A -7265.0
KLC4 -7349.0
H2AZ1 -7369.0
DYNLL2 -7375.0
FMNL2 -7431.0
NUP43 -7764.0
H3-3B -7982.0
SGO1 -7992.0
ACTG1 -8054.0
TUBA8 -8057.0
RAC1 -8281.0
NCF4 -8667.0
H2AC8 -8778.0
TUBA3D -8798.0
KIF5A -8814.0
CDC20 -8838.0
DSN1 -8883.0
ACTR2 -8931.0
ITGB1 -9031.0
KLK2 -9056.0
H2BC8 -9079.0
PMF1 -9098.0
CENPM -9662.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
ACTB -10333.0
TUBA3E -10348.0
NUP85 -10353.0
MYLK -10393.0
ARPC1B -10420.0
S100A8 -10656.0
PPP2CB -10912.0
CDH1 -10913.0
H3C12 -10932.0
SKA1 -11071.0
PPP1CC -11311.0
SFN -11352.0


REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
216
set REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
setSize 14
pANOVA 0.00559
s.dist -0.428
p.adjustANOVA 0.255



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
CRP -10819
MASP1 -10383
FCN3 -10157
C1QB -10126
MBL2 -9077
C1S -5493
COLEC10 -5455
COLEC11 -5126
MASP2 -3170
C1QC 1879
C1R 3059
C1QA 6057

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -11633
FCN2 -11559
CRP -10819
MASP1 -10383
FCN3 -10157
C1QB -10126
MBL2 -9077
C1S -5493
COLEC10 -5455
COLEC11 -5126
MASP2 -3170
C1QC 1879
C1R 3059
C1QA 6057


REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
1355
set REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
setSize 299
pANOVA 0.00658
s.dist 0.0913
p.adjustANOVA 0.292



Top enriched genes

Top 20 genes
GeneID Gene Rank
SUZ12 9441
AGO1 9194
BMI1 9147
HGF 9119
PIP4K2B 9086
PIP4K2C 8803
EPGN 8762
KLB 8587
PSMD13 8524
NBEA 8400
BTC 8294
FGF19 8285
PPP2R5D 8269
RNF146 8213
LAMTOR3 8110
FGF23 8075
MTA3 8017
PPP2R5B 7999
TRAF6 7953
PPP2R1B 7726

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SUZ12 9441
AGO1 9194
BMI1 9147
HGF 9119
PIP4K2B 9086
PIP4K2C 8803
EPGN 8762
KLB 8587
PSMD13 8524
NBEA 8400
BTC 8294
FGF19 8285
PPP2R5D 8269
RNF146 8213
LAMTOR3 8110
FGF23 8075
MTA3 8017
PPP2R5B 7999
TRAF6 7953
PPP2R1B 7726
PSMF1 7714
FRS2 7697
PDPK1 7458
CD28 7446
PRKAR1B 7392
GSK3A 7323
HDAC1 7322
PSMD11 7309
MTOR 7178
MKRN1 7135
HDAC3 7126
LAMTOR4 7004
PPARG 6934
PSME4 6905
PSMA2 6867
PIP4K2A 6788
OTUD3 6737
TNRC6C 6711
PSMC6 6685
TNKS 6617
CHUK 6603
MAPKAP1 6583
FGF2 6490
PLCG1 6466
CBX2 6305
PSMB6 6285
AKT2 6231
LAMTOR1 6216
IL1RL1 6193
RICTOR 6152
WWP2 6139
TSC2 5999
IL33 5933
PPP2R5A 5717
FOXO3 5693
NRG4 5639
EZH2 5620
CAMKK2 5596
ADCY9 5492
NR2E1 5474
PSMD9 5439
CSNK2B 5425
PIP5K1A 5399
ESR1 5343
RPTOR 5338
SNAI1 5300
PIK3CA 5267
ADCY3 5263
PSMD7 5071
NEDD4 4997
PHLPP2 4935
PSMB3 4905
PSMB7 4896
PRKCA 4876
AGO2 4867
PIK3R1 4837
PHC3 4830
PDE1B 4770
PPP2R5C 4507
REST 4325
AKT3 4319
PRKACB 4309
KIT 4302
PIK3R2 4257
HBEGF 4189
PSMB1 4033
PSMA5 4001
PSMD14 3838
CDKN1A 3835
PREX2 3744
PIP5K1C 3736
SCMH1 3707
THEM4 3616
HDAC2 3563
AREG 3387
FGF22 3315
KDM1A 3304
MTA1 3198
ITPR2 3140
EREG 3106
EED 3060
PSMD12 3007
MECOM 2999
FGF8 2684
PSMA4 2616
PSME1 2536
HDAC7 2503
USP13 2456
LAMTOR2 2452
CBX4 2447
PML 2311
TRIM27 2257
GAB1 2190
IRS2 2153
GAB2 1949
CHD3 1941
ERBB4 1896
RPS27A 1837
PPP2CA 1817
TNRC6A 1810
ITPR1 1737
RNF2 1715
PRKACG 1714
FLT3LG 1647
PRKCD 1634
CD19 1628
PIK3CB 1590
LAMTOR5 1572
MBD3 1368
GRB2 1328
CAMK4 1186
KPNA2 1103
LCK 1044
GSK3B 1036
ITPR3 994
KL 894
PSMD1 886
MAPK3 866
FGF20 682
PSMD6 572
PSMC3 570
SALL4 567
SRC 550
PSMB2 533
GATAD2B 485
KITLG 482
PSMD8 460
ADCY8 394
FGFR2 370
PSMA3 337
CAMKK1 336
PHC1 323
RRAGA 215
STRN 172
PSMD5 170
CAMK2D -17
CHD4 -106
RAC2 -151
FGF4 -198
BAD -203
RRAGD -286
ADCY7 -430
ATN1 -480
SEM1 -525
ESR2 -551
PSMA1 -810
FGF18 -835
PRR5 -900
MOV10 -904
CASP9 -961
FGF10 -970
RCOR1 -997
FRK -1029
CAMK2G -1167
INS -1171
AKT1S1 -1188
CALM1 -1278
PPP2R1A -1400
CSNK2A2 -1512
MDM2 -1544
CBX8 -1633
FGFR1 -1638
RBBP4 -1649
ERBB3 -1703
RING1 -1753
RPS6KB2 -1828
GATAD2A -1886
AGO4 -1920
TRIB3 -1981
RRAGC -2136
PDE1C -2159
PSME2 -2199
PSMD4 -2411
SLC38A9 -2609
PHC2 -2666
FLT3 -2770
CDKN1B -2790
VAV1 -2815
PRKCG -2960
JUN -2983
FOXO1 -3163
RHOG -3249
IER3 -3296
FGFR3 -3355
NRG1 -3375
IRAK4 -3418
FGF9 -3471
TNKS2 -3536
EGR1 -3639
PRKAR1A -3766
PRKCE -3829
IL1RAP -3848
MAPK1 -3902
PIK3CD -3974
PIK3AP1 -4001
RHEB -4109
FGF5 -4112
INSR -4173
PPP2R5E -4190
HDAC5 -4266
PRKAR2B -4343
PSMB5 -4359
TNRC6B -4433
AHCYL1 -4527
MET -4670
ERBB2 -4711
PDE1A -4712
PSMD3 -4790
PSMD2 -4823
PSMA7 -4955
PSMA8 -4966
TGFA -5021
PSMB8 -5035
PIP5K1B -5180
PSMB9 -5459
AGO3 -5584
AKT1 -5586
ATF2 -5645
PTEN -5671
PSMA6 -5784
STUB1 -5809
PSMC2 -5834
PSMC4 -5874
FGFR4 -5902
PDGFRA -5958
ADCY6 -6082
CBX6 -6482
UBB -6535
IRS1 -6825
PSMC1 -6897
ADCY2 -6936
PIK3R3 -7035
CSNK2A1 -7041
PRKAR2A -7077
FGF6 -7152
PRKACA -7200
UBC -7308
EGFR -7397
TRAT1 -7422
PSME3 -7475
PDGFA -7491
PSMB4 -7626
PSMC5 -7743
ADCY4 -7912
UBA52 -8101
CAMK2B -8137
FYN -8164
MYD88 -8168
FGF7 -8198
PHLPP1 -8222
MAF1 -8253
MLST8 -8255
RAC1 -8281
CREB1 -8293
TP53 -8352
FGF3 -8519
NRG3 -8567
MTA2 -9053
FGF1 -9356
ADCY5 -9366
USP7 -9538
ADCY1 -9551
EGF -9564
SNAI2 -9618
PDGFRB -9703
NRG2 -9707
CD80 -9716
GRK2 -9782
CD86 -9840
PSMB10 -10166
FOXO6 -10350
NR4A1 -10711
FGF17 -10731
PTPN11 -10878
PPP2CB -10912
PDGFB -11134
ICOS -11202
CAMK2A -11296
PSMB11 -11624


REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
594
set REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize 312
pANOVA 0.00696
s.dist -0.0888
p.adjustANOVA 0.301



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
GPHA2 -11875
EDN2 -11812
CCR6 -11704
CXCR5 -11616
CCL20 -11615
FSHB -11607
CCL1 -11605
CCL13 -11584
SUCNR1 -11581
CCL5 -11555
PPBP -11501
GPR132 -11441
CMKLR1 -11353
P2RY2 -11337

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12119
CCL22 -12115
AVP -11978
TAC3 -11952
CCL7 -11939
CCL16 -11904
GPHA2 -11875
EDN2 -11812
CCR6 -11704
CXCR5 -11616
CCL20 -11615
FSHB -11607
CCL1 -11605
CCL13 -11584
SUCNR1 -11581
CCL5 -11555
PPBP -11501
GPR132 -11441
CMKLR1 -11353
P2RY2 -11337
PROKR1 -11261
RXFP4 -11248
CX3CR1 -11186
LTB4R2 -11180
NPFF -11121
C5AR1 -11113
ACKR2 -11069
KEL -11029
PROK1 -11025
F2RL2 -11008
NPBWR2 -10976
CXCL10 -10918
ACKR1 -10882
CCR5 -10843
F2RL3 -10796
ADORA1 -10781
EDNRA -10732
AGT -10682
SAA1 -10622
ADRA2B -10619
GALR3 -10505
CCL21 -10468
ADRA1D -10425
CX3CL1 -10395
FPR2 -10391
RHO -10342
RLN3 -10264
APLNR -10187
CCL11 -10184
UTS2 -10158
CXCL12 -10139
NPFFR1 -10084
CCL23 -9956
LHCGR -9858
C5AR2 -9813
AVPR1B -9803
NPY5R -9752
CHRM4 -9709
CCL19 -9668
GPR4 -9574
PLPPR3 -9553
CCL27 -9397
PNOC -9350
QRFP -9327
DRD2 -9303
CCKBR -9263
NPSR1 -9249
EDN1 -9154
GRP -9139
UTS2B -9125
P2RY11 -9090
PDYN -9088
NMBR -8991
HTR5A -8917
CXCL5 -8881
CHRM3 -8878
PLPPR2 -8867
CCL2 -8841
CCL17 -8684
CHRM1 -8632
FSHR -8623
TACR2 -8616
P2RY6 -8575
GPR37L1 -8548
NPY -8526
GNRHR -8492
RGR -8468
LTB4R -8403
ADRA1B -8348
S1PR4 -8278
CXCL9 -8044
GPR55 -7997
GPBAR1 -7960
TAC1 -7957
ADORA2B -7945
NMS -7934
LPAR2 -7861
NPBWR1 -7813
NMUR1 -7471
HRH1 -7438
LPAR1 -7430
NPY2R -7413
BDKRB2 -7167
F2 -6955
GPR183 -6922
GAL -6918
PYY -6904
CNR1 -6794
HRH4 -6767
CGA -6754
PMCH -6742
GALR2 -6733
HTR4 -6557
GPR39 -6458
HRH2 -6296
OXER1 -6157
CCR10 -6085
F2R -6072
ADRA1A -6046
C3 -5985
FPR3 -5898
OPN5 -5826
HTR2A -5729
OPRL1 -5660
GPER1 -5597
NTSR1 -5379
MC1R -5172
HTR1A -5146
OXTR -5097
ADRB1 -4982
S1PR1 -4978
AGTR1 -4920
GPR68 -4913
TACR3 -4814
MLN -4744
PPY -4632
CXCL13 -4617
EDN3 -4593
BDKRB1 -4562
FFAR4 -4371
GNRH2 -4274
HRH3 -4261
KISS1 -4245
MC2R -4210
CXCL16 -3961
INSL5 -3870
PTGER3 -3853
FFAR2 -3662
CHRM2 -3573
TBXA2R -3546
GPR35 -3377
NPS -3203
RXFP1 -3179
PRLHR -3098
APP -3074
CXCL3 -2985
KNG1 -2955
GPR17 -2926
CXCR2 -2896
NPW -2876
NTSR2 -2798
EDNRB -2656
P2RY14 -2604
HTR1B -2506
OPRM1 -2352
CXCR4 -2312
TAAR5 -2291
CCK -2171
OPRK1 -2124
LPAR3 -2109
HTR7 -2042
PLPPR5 -2039
RLN2 -2037
SSTR2 -1673
P2RY1 -1654
CCR8 -1546
PLPPR1 -1538
ECE2 -1384
HCRTR1 -1264
CNR2 -1235
SST -1115
HTR1F -967
TSHR -838
GALR1 -530
NMU -419
POMC -331
PROKR2 -292
OPN1SW -141
DRD1 -132
PROK2 -126
S1PR2 16
S1PR5 49
HTR6 169
MC3R 483
TRH 599
P2RY13 677
C5 686
PTGDR 946
MLNR 1051
ADRB2 1122
C3AR1 1333
LPAR5 1531
GNRH1 1661
ACKR3 2034
HEBP1 2371
CORT 2395
MCHR1 2471
PSAP 2542
MTNR1A 2609
PTGDR2 2704
NTS 2849
TACR1 2882
TSHB 2901
GPR18 3120
CXCR6 3143
SSTR5 3339
AVPR1A 3341
P2RY12 3523
TAAR2 3605
PLPPR4 3625
NPY1R 3677
MCHR2 3692
OPRD1 3708
HTR1E 3852
CXCR1 3879
PTGIR 3883
OPN3 3942
OPN4 3977
HCRTR2 4016
PTGFR 4034
KISS1R 4153
HTR1D 4372
PENK 4420
HCRT 4431
ECE1 4525
PTGER4 4574
GHRL 4611
RXFP2 4861
XCL1 4984
FPR1 5077
CCKAR 5086
ANXA1 5126
GHSR 5169
CXCL8 5213
DRD3 5227
CHRM5 5253
ADRB3 5364
TRHR 5668
TAAR8 5729
PTGER1 5752
ACKR4 5792
SSTR3 5835
CXCL2 5948
INSL3 6113
CCR7 6179
ADRA2C 6213
NLN 6295
XCL2 6376
MC4R 6494
HCAR1 6641
LPAR6 6681
XCR1 6784
PTGER2 6791
NMUR2 6859
F2RL1 7056
MTNR1B 7134
CCR2 7161
ADRA2A 7162
RXFP3 7275
CCL28 7436
PTAFR 7505
GPR37 7511
SSTR4 7518
PF4 7540
CCR4 7589
CCL3 7624
CCR3 7679
RRH 7801
PRLH 7813
DRD5 7822
TAAR9 7856
NPB 7864
QRFPR 7876
NMB 7928
CCL25 8003
DRD4 8219
MC5R 8225
CCRL2 8328
SSTR1 8425
GPR31 8435
NPFFR2 8447
FFAR1 8545
TAAR1 8771
UTS2R 8799
HTR2B 8869
OXGR1 8930
ADORA3 8933
CXCL6 9000
CCR1 9067
FFAR3 9102
OXT 9140
GPR65 9229
LHB 9274
CXCL11 9340
GPHB5 9404
HCAR2 9458
ADORA2A 9467
CXCL1 9475
CYSLTR2 9512
CCR9 9543
TAAR6 9544
S1PR3 9641


REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES
1004
set REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES
setSize 187
pANOVA 0.00774
s.dist 0.113
p.adjustANOVA 0.315



Top enriched genes

Top 20 genes
GeneID Gene Rank
TGFBR1 9195.0
RIPK1 8935.0
H2AC17 8661.0
AXIN2 8621.0
H2BC17 8591.0
PSMD13 8524.0
USP33 8337.0
RNF146 8213.0
SMURF2 8023.0
TRAF6 7953.0
PSMF1 7714.0
PSMD11 7309.0
H2BC9 7299.5
PSME4 6905.0
USP16 6904.0
PSMA2 6867.0
KAT2A 6840.0
STAM2 6747.0
USP8 6699.0
PSMC6 6685.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TGFBR1 9195.0
RIPK1 8935.0
H2AC17 8661.0
AXIN2 8621.0
H2BC17 8591.0
PSMD13 8524.0
USP33 8337.0
RNF146 8213.0
SMURF2 8023.0
TRAF6 7953.0
PSMF1 7714.0
PSMD11 7309.0
H2BC9 7299.5
PSME4 6905.0
USP16 6904.0
PSMA2 6867.0
KAT2A 6840.0
STAM2 6747.0
USP8 6699.0
PSMC6 6685.0
SUDS3 6676.0
TNKS 6617.0
CLSPN 6574.0
IFIH1 6444.0
UFD1 6292.0
PSMB6 6285.0
USP15 6151.0
TRRAP 6116.0
USP22 6064.0
IL33 5933.0
USP44 5862.0
H2BC12 5854.0
H2AC4 5676.0
H2AC20 5583.0
PSMD9 5439.0
MDM4 5418.0
USP42 5408.0
USP4 5372.0
CCNA2 5259.0
PSMD7 5071.0
USP28 5019.0
PSMB3 4905.0
PSMB7 4896.0
USP21 4866.0
SIAH2 4839.0
FKBP8 4676.0
USP30 4671.0
WDR20 4666.0
WDR48 4502.0
ATXN7 4231.0
H2BC13 4070.0
PSMB1 4033.0
TADA2B 4019.0
PSMA5 4001.0
PSMD14 3838.0
H2AC7 3829.5
H2BC7 3829.5
H2BC6 3659.0
SMAD2 3580.0
ARRB1 3508.0
SMAD1 3494.0
CDC25A 3199.0
RUVBL1 3185.0
H2AC18 3107.5
H2AC19 3107.5
PSMD12 3007.0
BIRC3 2918.0
PSMA4 2616.0
USP25 2614.0
PSME1 2536.0
USP13 2456.0
VDAC1 2375.0
MAT2B 2218.0
RHOT1 2161.0
BIRC2 2041.0
SMAD4 1939.0
RPS27A 1837.0
USP14 1770.0
CYLD 1689.0
TOMM70 1537.0
KEAP1 1532.0
TAB1 1505.0
H2BC4 1347.0
HGS 1269.0
USP20 1260.0
GATA3 1188.0
ADRB2 1122.0
TRAF2 1082.0
H2AC6 949.0
USP12 935.0
PSMD1 886.0
RNF123 749.0
H2BC21 723.0
USP47 674.0
PSMD6 572.0
PSMC3 570.0
PSMB2 533.0
USP3 532.0
PSMD8 460.0
H2AC11 355.0
PSMA3 337.0
H2AC12 334.0
PSMD5 170.0
H2BC5 -9.0
SKP2 -107.0
SNX3 -291.0
H2AC13 -397.0
SEM1 -525.0
MAP3K7 -559.0
SMAD7 -785.0
PSMA1 -810.0
IDE -847.0
USP34 -951.0
H2BC10 -1032.0
POLB -1123.0
H2AC21 -1383.0
H2BC15 -1414.0
MUL1 -1486.0
MDM2 -1544.0
ARRB2 -1550.0
USP10 -2148.0
PSME2 -2199.0
TADA3 -2200.0
USP49 -2233.0
DDB2 -2351.0
TAF10 -2376.0
PSMD4 -2411.0
VDAC3 -2460.0
H2AC15 -2567.0
RCE1 -2901.0
H2BC3 -2958.0
TNKS2 -3536.0
BECN1 -3611.0
HIF1A -3630.0
VDAC2 -3672.0
SMAD3 -3680.0
TOMM20 -3842.0
CFTR -3968.0
PSMB5 -4359.0
MYC -4660.0
PSMD3 -4790.0
PSMD2 -4823.0
USP48 -4948.0
PSMA7 -4955.0
PSMA8 -4966.0
H2AC25 -4996.0
PSMB8 -5035.0
USP18 -5248.0
USP24 -5439.0
PSMB9 -5459.0
USP37 -5658.0
PTEN -5671.0
PSMA6 -5784.0
PSMC2 -5834.0
PSMC4 -5874.0
USP5 -6040.0
AXIN1 -6148.0
H2AC1 -6184.0
H2BC1 -6416.0
NFKBIA -6526.0
UBB -6535.0
CCP110 -6659.0
ADRM1 -6746.0
H2BC11 -6780.0
H2BC26 -6814.0
PSMC1 -6897.0
CCNA1 -7274.0
UBC -7308.0
PSME3 -7475.0
OTUB1 -7506.0
PSMB4 -7626.0
PSMC5 -7743.0
H2AC16 -7951.0
UBA52 -8101.0
TP53 -8352.0
H2AC8 -8778.0
CDC20 -8838.0
USP2 -8908.0
H2BC8 -9079.0
USP19 -9244.0
RIGI -9390.0
USP7 -9538.0
H2BC14 -9980.0
H2AC14 -10060.0
PSMB10 -10166.0
PTRH2 -10325.0
PSMB11 -11624.0


REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY

REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
635
set REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
setSize 64
pANOVA 0.00774
s.dist 0.192
p.adjustANOVA 0.315



Top enriched genes

Top 20 genes
GeneID Gene Rank
HLA-DQA1 9240
CD3E 8820
CD3G 8811
CD247 8595
GRAP2 8590
PPP2R5D 8269
PPP2R5B 7999
CD3D 7917
HLA-DRA 7832
PDCD1LG2 7819
HLA-DPB1 7745
PPP2R1B 7726
BTLA 7712
PDPK1 7458
CD28 7446
MTOR 7178
HLA-DPA1 7053
CTLA4 6701
MAPKAP1 6583
AKT2 6231

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HLA-DQA1 9240
CD3E 8820
CD3G 8811
CD247 8595
GRAP2 8590
PPP2R5D 8269
PPP2R5B 7999
CD3D 7917
HLA-DRA 7832
PDCD1LG2 7819
HLA-DPB1 7745
PPP2R1B 7726
BTLA 7712
PDPK1 7458
CD28 7446
MTOR 7178
HLA-DPA1 7053
CTLA4 6701
MAPKAP1 6583
AKT2 6231
RICTOR 6152
PPP2R5A 5717
PIK3CA 5267
CD274 5054
PIK3R1 4837
PAK2 4670
PPP2R5C 4507
CDC42 4492
AKT3 4319
PIK3R2 4257
THEM4 3616
HLA-DQB1 2592
CSK 2358
PPP2CA 1817
GRB2 1328
LCK 1044
SRC 550
HLA-DQA2 -313
PRR5 -900
MAP3K14 -1240
PPP2R1A -1400
PAK1 -1880
LYN -1937
TRIB3 -1981
MAP3K8 -2258
VAV1 -2815
YES1 -4046
PPP2R5E -4190
AKT1 -5586
HLA-DQB2 -5718
CD4 -6717
HLA-DRB1 -6804
PIK3R3 -7035
PTPN6 -7632
FYN -8164
HLA-DRB5 -8197
MLST8 -8255
RAC1 -8281
PDCD1 -9112
CD80 -9716
CD86 -9840
PTPN11 -10878
PPP2CB -10912
ICOS -11202


REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
115
set REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
setSize 134
pANOVA 0.00788
s.dist -0.133
p.adjustANOVA 0.315



Top enriched genes

Top 20 genes
GeneID Gene Rank
MMP8 -11878
PRSS1 -11874
MMP19 -11612
CAPN13 -11500
MMP20 -11366
CDH1 -10913
MMP11 -10877
COL13A1 -10837
CAPN12 -10496
MMP24 -10412
MMP1 -10285
CTSD -10276
COL7A1 -10232
COL17A1 -9936
CAPN5 -9927
TIMP2 -9890
CAPN11 -9795
COL8A2 -9750
MMP17 -9447
ADAMTS1 -9373

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MMP8 -11878
PRSS1 -11874
MMP19 -11612
CAPN13 -11500
MMP20 -11366
CDH1 -10913
MMP11 -10877
COL13A1 -10837
CAPN12 -10496
MMP24 -10412
MMP1 -10285
CTSD -10276
COL7A1 -10232
COL17A1 -9936
CAPN5 -9927
TIMP2 -9890
CAPN11 -9795
COL8A2 -9750
MMP17 -9447
ADAMTS1 -9373
COL23A1 -9232
TMPRSS6 -9197
SCUBE1 -9183
KLK2 -9056
COL16A1 -8919
HSPG2 -8775
ELANE -8725
LAMB3 -8550
CTRB1 -8317
ADAMTS4 -8177
MMP9 -8176
OPTC -7816
ACAN -7784
ADAMTS18 -7747
MMP12 -7671
COL9A3 -7637
COL5A3 -7318
KLKB1 -7185
LAMC1 -6839
COL9A2 -6827
CAPNS2 -6596
TLL2 -6593
PLG -6247
FBN1 -5910
CAPN9 -5850
MMP16 -5624
CAPN7 -5609
ELN -5410
HTRA1 -5322
COL14A1 -5205
NID1 -5124
CMA1 -4997
CTRB2 -4608
COL15A1 -4529
CAPN14 -4470
NCSTN -4289
ADAM9 -4176
MMP2 -3801
CTSG -3799
ADAMTS9 -3685
COL1A1 -3665
COL11A2 -3555
ADAMTS5 -3373
COL4A4 -3267
COL4A2 -3113
COL6A3 -3107
COL5A2 -2914
ADAM15 -2449
MMP13 -2272
COL11A1 -2196
CTSV -2142
CAPN8 -2141
COL9A1 -2035
ADAMTS16 -1949
LAMA5 -1833
CAPN2 -1758
FURIN -1473
CAST -1413
COL8A1 -1267
KLK7 -1195
COL5A1 -1138
FN1 -1014
TLL1 -821
ADAMTS8 -795
CAPN1 -697
ADAM17 -560
SCUBE3 -369
CD44 -351
COL25A1 -69
MMP3 0
PSEN1 218
COL6A5 261
COL26A1 316
COL3A1 796
CAPN3 1332
COL2A1 1379
CAPN10 1512
LAMC2 1685
CASP3 1797
BMP1 1861
SPP1 2012
DCN 2166
LAMA3 2475
COL12A1 2489
COL18A1 2506
COL4A3 2673
SPOCK3 2697
FBN2 2827
COL19A1 2994
CAPNS1 3023
MMP14 3217
PHYKPL 3357
MMP15 3832
COL4A1 3956
COL6A6 4006
FBN3 4021
BCAN 4254
CTSB 4265
MMP25 4596
LAMB1 5074
COL6A1 5298
COL10A1 5848
CTSL 6187
COL6A2 6308
CTSS 6756
ADAM8 6773
COL1A2 6930
BSG 7084
MMP10 7544
CAPN15 8076
A2M 8290
ADAM10 8404
MMP7 8544
CTSK 9490


REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
381
set REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX
setSize 85
pANOVA 0.00816
s.dist 0.166
p.adjustANOVA 0.319



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C1 9085.0
H2AZ2 8952.0
AXIN2 8621.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
CREBBP 8084.0
LEF1 8081.0
KMT2D 7924.0
H3-4 7608.0
HDAC1 7322.0
H2BC9 7299.5
H3C7 7299.5
TCF7 7254.0
BCL9L 6272.0
TRRAP 6116.0
H4C3 6009.0
H2BC12 5854.0
H2AC4 5676.0
H2AC20 5583.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C1 9085.0
H2AZ2 8952.0
AXIN2 8621.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
CREBBP 8084.0
LEF1 8081.0
KMT2D 7924.0
H3-4 7608.0
HDAC1 7322.0
H2BC9 7299.5
H3C7 7299.5
TCF7 7254.0
BCL9L 6272.0
TRRAP 6116.0
H4C3 6009.0
H2BC12 5854.0
H2AC4 5676.0
H2AC20 5583.0
H3C8 5547.0
H4C9 5306.0
ASH2L 4906.0
H4C6 4702.0
H3-3A 4158.0
CTNNB1 4100.0
H2BC13 4070.0
TLE3 3902.0
H2AC7 3829.5
H2BC7 3829.5
BCL9 3721.0
H2BC6 3659.0
CDC73 3203.0
RUVBL1 3185.0
H2AC18 3107.5
H2AC19 3107.5
TERT 3095.0
H4C16 2844.0
PYGO2 2582.0
H4C1 2332.0
H3C11 2270.0
H2AJ 2047.0
SMARCA4 1900.0
H3C6 1887.0
PYGO1 1390.0
H2BC4 1347.0
H3C2 1183.0
H2AC6 949.0
H2BC21 723.0
TLE2 136.0
EP300 15.0
H2BC5 -9.0
H3C4 -374.0
TLE4 -718.0
H2BC10 -1032.0
H2BC15 -1414.0
H2AX -1653.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
RUNX3 -2818.0
H2BC3 -2958.0
H4C11 -3485.0
TCF4 -3909.0
LEO1 -4029.0
MYC -4660.0
MEN1 -4780.0
TCF7L2 -4825.0
TCF7L1 -5388.0
H3C3 -5940.0
H2BC1 -6416.0
H2BC11 -6780.0
H2BC26 -6814.0
TLE1 -6861.0
H4C2 -7011.0
H2AZ1 -7369.0
H3-3B -7982.0
KAT5 -8090.0
RBBP5 -8717.0
H2AC8 -8778.0
H2BC8 -9079.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
H3C12 -10932.0


REACTOME_CELL_CYCLE_CHECKPOINTS

REACTOME_CELL_CYCLE_CHECKPOINTS
1120
set REACTOME_CELL_CYCLE_CHECKPOINTS
setSize 284
pANOVA 0.00882
s.dist 0.0903
p.adjustANOVA 0.337



Top enriched genes

Top 20 genes
GeneID Gene Rank
MAPRE1 8713
KNTC1 8636
ANAPC15 8606
H2BC17 8591
H4C12 8556
PSMD13 8524
RNF8 8486
MCM6 8397
PPP2R5D 8269
H4C5 8212
CLIP1 8150
CLASP2 8135
PHF20 8130
PPP2R5B 7999
TAOK1 7879
CENPO 7809
MAD1L1 7744
PPP2R1B 7726
PSMF1 7714
RPS27 7711

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MAPRE1 8713.0
KNTC1 8636.0
ANAPC15 8606.0
H2BC17 8591.0
H4C12 8556.0
PSMD13 8524.0
RNF8 8486.0
MCM6 8397.0
PPP2R5D 8269.0
H4C5 8212.0
CLIP1 8150.0
CLASP2 8135.0
PHF20 8130.0
PPP2R5B 7999.0
TAOK1 7879.0
CENPO 7809.0
MAD1L1 7744.0
PPP2R1B 7726.0
PSMF1 7714.0
RPS27 7711.0
RPA3 7645.0
H3-4 7608.0
PCBP4 7569.0
CDC7 7461.0
BABAM1 7457.0
HERC2 7326.0
CDK1 7310.0
PSMD11 7309.0
H2BC9 7299.5
B9D2 7287.0
RPA1 7231.0
HUS1 7120.0
ANAPC5 7097.0
SEH1L 7023.0
PSME4 6905.0
PSMA2 6867.0
ATR 6854.0
NSD2 6769.0
DYNC1LI1 6729.0
PSMC6 6685.0
DYNC1H1 6601.0
CLSPN 6574.0
SPC24 6531.0
AURKB 6511.0
CENPF 6418.0
INCENP 6349.0
PSMB6 6285.0
ORC1 6269.0
H4C3 6009.0
UBE2V2 5978.0
CDC45 5959.0
NDEL1 5866.0
H2BC12 5854.0
ANAPC16 5819.0
TOP3A 5734.0
PPP2R5A 5717.0
RMI2 5558.0
PSMD9 5439.0
MDM4 5418.0
H4C9 5306.0
BABAM2 5265.0
CCNA2 5259.0
ANAPC10 5142.0
PSMD7 5071.0
PSMB3 4905.0
PSMB7 4896.0
NUP98 4773.0
CENPE 4766.0
H4C6 4702.0
YWHAZ 4640.0
PPP2R5C 4507.0
KIF2C 4469.0
MDC1 4416.0
KNL1 4393.0
PIAS4 4387.0
NUP160 4345.0
KIF18A 4221.0
ORC5 4105.0
RNF168 4092.0
H2BC13 4070.0
PSMB1 4033.0
NDE1 4024.0
PSMA5 4001.0
NUF2 3895.0
ANAPC2 3845.0
PSMD14 3838.0
CDKN1A 3835.0
H2BC7 3829.5
TP53BP1 3700.0
CENPK 3678.0
H2BC6 3659.0
ATM 3411.0
CENPN 3409.0
CKAP5 3390.0
RCC2 3360.0
DNA2 3220.0
CDC25A 3199.0
ORC3 3176.0
BIRC5 3110.0
BUB1B 3099.0
DYNC1I2 3054.0
NUP37 3040.0
PSMD12 3007.0
MCM3 3003.0
H4C16 2844.0
BUB3 2757.0
RAD17 2685.0
PSMA4 2616.0
PSME1 2536.0
BRIP1 2420.0
EXO1 2346.0
CENPU 2336.0
H4C1 2332.0
SGO2 2287.0
CDK2 2115.0
SEC13 1952.0
RPS27A 1837.0
PPP2CA 1817.0
CDC27 1790.0
MRE11 1757.0
CENPA 1710.0
CHEK2 1591.0
NUP107 1476.0
H2BC4 1347.0
MCM4 1246.0
CENPH 1223.0
BRCA1 1137.0
CLASP1 1102.0
MAD2L1 1096.0
PSMD1 886.0
BUB1 812.0
RPA2 810.0
CDC25C 737.0
COP1 725.0
H2BC21 723.0
CDC23 687.0
ANAPC1 671.0
PSMD6 572.0
PSMC3 570.0
CHEK1 534.0
PSMB2 533.0
PSMD8 460.0
ORC2 455.0
AHCTF1 452.0
PSMA3 337.0
RFC3 302.0
YWHAG 201.0
PSMD5 170.0
UBE2D1 159.0
H2BC5 -9.0
CENPT -26.0
ORC4 -175.0
DYNC1I1 -433.0
SEM1 -525.0
DBF4 -563.0
PSMA1 -810.0
ZWILCH -1021.0
H2BC10 -1032.0
RANGAP1 -1150.0
CCNE1 -1248.0
MCM7 -1282.0
NSL1 -1316.0
ABRAXAS1 -1380.0
PPP2R1A -1400.0
H2BC15 -1414.0
NUDC -1543.0
MDM2 -1544.0
H2AX -1653.0
NDC80 -1672.0
RMI1 -2047.0
PSME2 -2199.0
ZWINT -2209.0
PAFAH1B1 -2384.0
PSMD4 -2411.0
CDCA8 -2485.0
MIS12 -2586.0
YWHAE -2626.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
WEE1 -2759.0
ZW10 -2773.0
CDKN1B -2790.0
H2BC3 -2958.0
RANBP2 -2965.0
NUP133 -2987.0
CDC6 -3027.0
PKMYT1 -3165.0
MCM10 -3229.0
DYNLL1 -3248.0
MCM8 -3339.0
SPDL1 -3435.0
UBE2E1 -3458.0
H4C11 -3485.0
MCM2 -3545.0
CDKN2A -3687.0
ITGB3BP -3696.0
RFC2 -3795.0
CENPS -3932.0
CCNB1 -3983.0
ANAPC11 -4140.0
PPP2R5E -4190.0
RAD9B -4195.0
DYNC1LI2 -4243.0
PSMB5 -4359.0
RFC5 -4509.0
BLM -4634.0
BARD1 -4746.0
PSMD3 -4790.0
PLK1 -4822.0
PSMD2 -4823.0
YWHAQ -4844.0
GTSE1 -4894.0
PSMA7 -4955.0
PSMA8 -4966.0
WRN -4967.0
PSMB8 -5035.0
YWHAH -5306.0
CCNB2 -5336.0
PSMB9 -5459.0
ANAPC7 -5464.0
CDC26 -5475.0
RAD9A -5498.0
CENPC -5501.0
SKA2 -5511.0
NBN -5647.0
XPO1 -5699.0
PSMA6 -5784.0
PSMC2 -5834.0
PSMC4 -5874.0
RFC4 -5956.0
ANAPC4 -6057.0
CENPL -6355.0
H2BC1 -6416.0
YWHAB -6461.0
UBB -6535.0
ZNF385A -6771.0
H2BC11 -6780.0
H2BC26 -6814.0
PSMC1 -6897.0
TOPBP1 -6914.0
SPC25 -6926.0
H4C2 -7011.0
CENPP -7022.0
CENPQ -7094.0
UIMC1 -7124.0
MCM5 -7159.0
KIF2B -7248.0
KIF2A -7265.0
CCNA1 -7274.0
UBE2S -7305.0
UBC -7308.0
DYNLL2 -7375.0
PSME3 -7475.0
UBE2N -7482.0
CCNE2 -7568.0
PSMB4 -7626.0
PSMC5 -7743.0
NUP43 -7764.0
SGO1 -7992.0
KAT5 -8090.0
UBA52 -8101.0
TP53 -8352.0
CDC20 -8838.0
DSN1 -8883.0
H2BC8 -9079.0
PMF1 -9098.0
UBE2C -9239.0
RBBP8 -9329.0
ATRIP -9488.0
CENPM -9662.0
ORC6 -9809.0
CDC16 -9923.0
H2BC14 -9980.0
PSMB10 -10166.0
RHNO1 -10241.0
NUP85 -10353.0
RAD1 -10381.0
RAD50 -10384.0
PPP2CB -10912.0
SKA1 -11071.0
PPP1CC -11311.0
SFN -11352.0
PSMB11 -11624.0


REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
1591
set REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 33
pANOVA 0.00903
s.dist -0.263
p.adjustANOVA 0.337



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS15A -10613
RPS10 -10288
RPS15 -10280
RPS28 -9918
RPS8 -9901
FAU -8524
RPS2 -8500
RPS3A -8441
RPS18 -8407
RPS12 -8301
RPS25 -7758
RPS5 -7280
RPS13 -7029
RPS6 -6939
RPS20 -6260
RPS21 -5458
RPS24 -5072
RPS23 -4737
HNRNPA1 -3671
EEF1A1 -3420

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS15A -10613
RPS10 -10288
RPS15 -10280
RPS28 -9918
RPS8 -9901
FAU -8524
RPS2 -8500
RPS3A -8441
RPS18 -8407
RPS12 -8301
RPS25 -7758
RPS5 -7280
RPS13 -7029
RPS6 -6939
RPS20 -6260
RPS21 -5458
RPS24 -5072
RPS23 -4737
HNRNPA1 -3671
EEF1A1 -3420
RPS7 -2847
RPSA -2801
RPS27L -2334
RPS26 -2128
RPS3 -1606
RPS29 -1088
RPS11 -225
RPS16 1311
RPS27A 1837
RPS9 4427
RPS19 7158
RPS27 7711
RPS14 8094


REACTOME_MEIOTIC_SYNAPSIS

REACTOME_MEIOTIC_SYNAPSIS
54
set REACTOME_MEIOTIC_SYNAPSIS
setSize 73
pANOVA 0.00964
s.dist 0.175
p.adjustANOVA 0.352



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AZ2 8952.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
H3-4 7608.0
SYCP3 7516.0
SYNE2 7327.0
H2BC9 7299.5
REC8 7181.0
ATR 6854.0
SYCE3 6538.0
SYCE2 6034.0
H4C3 6009.0
TERF1 5972.0
H2BC12 5854.0
H2AC4 5676.0
SYCE1 5658.0
H2AC20 5583.0
SMC1B 5412.0
H4C9 5306.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AZ2 8952.0
H2BC17 8591.0
H4C12 8556.0
H4C5 8212.0
H3-4 7608.0
SYCP3 7516.0
SYNE2 7327.0
H2BC9 7299.5
REC8 7181.0
ATR 6854.0
SYCE3 6538.0
SYCE2 6034.0
H4C3 6009.0
TERF1 5972.0
H2BC12 5854.0
H2AC4 5676.0
SYCE1 5658.0
H2AC20 5583.0
SMC1B 5412.0
H4C9 5306.0
H4C6 4702.0
SUN2 4694.0
ACD 4581.5
UBE2I 4284.0
H2BC13 4070.0
POT1 4002.0
TINF2 3995.0
H2AC7 3829.5
H2BC7 3829.5
H2BC6 3659.0
STAG3 3116.0
H2AC18 3107.5
H2AC19 3107.5
SYCP1 3031.0
H4C16 2844.0
SYNE1 2516.0
H4C1 2332.0
SUN1 2149.0
H2AJ 2047.0
LMNB1 1405.0
H2BC4 1347.0
BRCA1 1137.0
H2AC6 949.0
H2BC21 723.0
STAG1 281.0
H2BC5 -9.0
DIDO1 -868.0
H2BC10 -1032.0
H2BC15 -1414.0
H2AX -1653.0
LMNA -2475.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
H2BC3 -2958.0
SYCP2 -3461.0
H4C11 -3485.0
TERF2IP -5287.0
H2BC1 -6416.0
HSPA2 -6496.0
H2BC11 -6780.0
H2BC26 -6814.0
H4C2 -7011.0
RAD21 -7170.0
H2AZ1 -7369.0
SMC3 -8093.0
TERF2 -8433.0
H2AC8 -8778.0
FKBP6 -8840.0
H2BC8 -9079.0
TEX12 -9889.0
H2BC14 -9980.0
H2AC14 -10060.0


REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT
729
set REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT
setSize 236
pANOVA 0.0107
s.dist -0.0964
p.adjustANOVA 0.379



Top enriched genes

Top 20 genes
GeneID Gene Rank
AVP -11978
SLC14A1 -11760
SLC7A7 -11692
SLC4A9 -11495
SLC13A5 -11468
SLC5A2 -11467
SLC18A1 -11421
SLC5A1 -11300
SLC24A3 -11252
SLC17A8 -11148
SLC28A3 -11122
SLC9A4 -11116
SLC1A5 -10857
SLC39A2 -10818
SLC26A9 -10795
SLC28A1 -10704
SLC16A3 -10633
SLC9A2 -10595
SLC6A7 -10524
SLCO2B1 -10460

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AVP -11978
SLC14A1 -11760
SLC7A7 -11692
SLC4A9 -11495
SLC13A5 -11468
SLC5A2 -11467
SLC18A1 -11421
SLC5A1 -11300
SLC24A3 -11252
SLC17A8 -11148
SLC28A3 -11122
SLC9A4 -11116
SLC1A5 -10857
SLC39A2 -10818
SLC26A9 -10795
SLC28A1 -10704
SLC16A3 -10633
SLC9A2 -10595
SLC6A7 -10524
SLCO2B1 -10460
SLC13A1 -10244
SLC45A3 -10195
SLC44A4 -10136
LCN9 -9970
SLC2A9 -9940
FGF21 -9930
SLC30A1 -9773
SLC22A15 -9764
SLC7A9 -9566
SLC4A1 -9470
SLC43A2 -9454
SLC6A13 -9337
SLC47A2 -9316
SLC22A11 -9271
SLC6A9 -9268
SLC24A4 -9209
SLC41A2 -9207
SLCO1C1 -9145
SLC5A11 -9119
SLC26A4 -9099
SLC30A2 -8989
SLCO2A1 -8945
SLC2A3 -8849
SLC44A5 -8780
SLC6A12 -8768
SLC34A3 -8539
SLC4A4 -8505
RHAG -8504
SLC39A10 -8498
SLC13A2 -8483
SLC25A10 -8355
RHBG -8334
SLCO4A1 -8152
SLC30A3 -8097
CTNS -8083
SLC22A8 -7952
SLC6A2 -7807
AHCYL2 -7769
SLC34A1 -7748
SLC1A6 -7704
LCN15 -7692
SLC3A2 -7435
SLC26A2 -7418
SLC26A1 -7210
SLC24A1 -7174
SLC22A7 -7169
SLC36A2 -7142
SLC39A6 -7044
SLC13A4 -7005
SLC2A6 -6917
SLC15A1 -6876
SLC38A1 -6691
SLC39A4 -6627
SLC8A2 -6623
SLC1A1 -6575
SLC17A6 -6548
SLC5A3 -6531
SLC30A8 -6435
RHCG -6426
SLC1A2 -6076
CP -6034
SLC27A4 -6032
SLC11A1 -5966
SLC8A3 -5878
SLC6A3 -5868
SLC22A2 -5656
SLC26A6 -5636
SLC2A4 -5480
SLC8A1 -5393
SLC22A4 -5236
SLC50A1 -5217
SLC2A12 -5204
SLC35B2 -5129
SLC33A1 -4971
SLC35D1 -4915
SLC2A1 -4722
SLC6A11 -4677
SRI -4582
SLC15A4 -4555
SLC40A1 -4465
SLC39A1 -4349
SLC5A6 -4344
SLC35A1 -4302
SLC5A7 -4117
SLC2A8 -3897
SLC5A4 -3774
SLC47A1 -3541
SLC27A1 -3507
SLC5A9 -3266
SLC13A3 -3251
SLC6A19 -3197
SLC44A1 -3143
SLC12A1 -3133
SLC36A1 -3062
SLC16A1 -2990
SLC4A10 -2973
SLC3A1 -2911
ARL2BP -2783
SLC38A3 -2532
SLC43A1 -2477
SLC1A7 -2341
SLC6A18 -2265
SLC9A5 -2041
SLC39A3 -1976
SLC29A3 -1877
SLC11A2 -1742
SLC7A5 -1567
SLC26A3 -1454
SLC2A13 -1372
CALM1 -1278
SLC22A3 -1243
SLC4A3 -977
SLC39A7 -932
SLC4A5 -927
SLC14A2 -786
SLCO1A2 -651
SLC2A11 -587
SLCO1B3 -469
SLC6A5 -237
SLC2A10 -173
SLC6A1 -133
SLC35D2 5
SLC12A4 228
SLC25A26 229
SLC22A16 244
SLC35B4 296
SLCO1B1 342
SLC44A3 352
SLC22A6 416
SLC17A7 461
SLC20A1 470
SLC29A2 499
SLC17A1 672
SLC25A22 678
SLC2A2 685
RUNX1 702
SLC7A11 751
SLC29A1 759
SLC2A14 882
SLC31A1 924
SLC26A11 1062
APOD 1064
SLC7A10 1211
SLC35B3 1254
SLC32A1 1372
SLC34A2 1406
SLC4A2 1423
SLC6A20 1669
SLC12A3 1687
SLC35C1 1749
SLC1A3 1829
SLC36A4 1975
SLC39A5 1980
SLC24A2 2028
SLC25A4 2119
SLC9A8 2537
SLC25A18 2714
SLC7A8 2728
SLC8B1 2755
MFSD4B 2980
SLC12A5 3119
SLC9A3 3505
SLC26A7 3705
EMB 3900
SLCO3A1 4008
SLC2A7 4300
SLC4A7 4337
SLC24A5 4355
SLC6A6 4588
SLC25A29 4603
SLC12A2 4628
SLC38A4 4740
SLC5A12 4755
SLC1A4 4762
SLC5A8 4788
SLC9A9 4790
SLC7A2 4832
SLC39A14 4929
SLC6A15 5049
SLC20A2 5113
SLC5A10 5158
SLC16A10 5229
SLC30A10 5309
SLC38A2 5407
SLC4A8 5508
SLC12A6 5705
SLC41A1 5962
SLC44A2 6003
SLC18A2 6040
SLC9A1 6226
SLC15A2 6287
SLC16A8 6553
LCN12 6579
SLC29A4 6789
SLC16A7 6801
SLC39A8 6919
SLC22A5 6956
SLC35A3 6971
SLC7A1 7042
BSG 7084
SLC12A7 7109
SLCO4C1 7818
ARL2 7880
SLC30A5 7934
SLC22A18 7952
SLC17A5 8168
SLC15A3 8211
SLC7A6 8380
SLC27A6 8418
SLC22A1 8689
SLC22A12 8779
SLC10A6 9029
SLC5A5 9141
SLC28A2 9546
RSC1A1 9573
LCN1 9639


REACTOME_ADAPTIVE_IMMUNE_SYSTEM

REACTOME_ADAPTIVE_IMMUNE_SYSTEM
79
set REACTOME_ADAPTIVE_IMMUNE_SYSTEM
setSize 729
pANOVA 0.0108
s.dist 0.0554
p.adjustANOVA 0.379



Top enriched genes

Top 20 genes
GeneID Gene Rank
BTN3A2 9725
CTSK 9490
CD79A 9360
PILRB 9312
ITGB7 9305
HLA-DQA1 9240
FGA 9219
TREML2 9177
ASB7 9103
TRIM21 9023
LAIR1 8996
CD160 8939
CD3E 8820
CD3G 8811
TUBA3C 8794
AP1S1 8694
ZNRF1 8668
LILRA4 8631
ASB5 8627
TUBB1 8617

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
BTN3A2 9725
CTSK 9490
CD79A 9360
PILRB 9312
ITGB7 9305
HLA-DQA1 9240
FGA 9219
TREML2 9177
ASB7 9103
TRIM21 9023
LAIR1 8996
CD160 8939
CD3E 8820
CD3G 8811
TUBA3C 8794
AP1S1 8694
ZNRF1 8668
LILRA4 8631
ASB5 8627
TUBB1 8617
HLA-F 8612
CD247 8595
GRAP2 8590
LRR1 8534
PSMD13 8524
CD200 8399
KIR3DL1 8325
KLRF1 8319
S100A9 8281
PPP2R5D 8269
UBR1 8259
SFTPD 8178
FBXW9 8165
BTN1A1 8147
CD33 8137
DCAF1 8063
SMURF2 8023
PPP2R5B 7999
CD79B 7987
SEC24B 7983
KLHL2 7955
TRAF6 7953
CD3D 7917
RNF34 7837
HLA-DRA 7832
PDCD1LG2 7819
HLA-DPB1 7745
PPP2R1B 7726
PSMF1 7714
BTLA 7712
CD1B 7685
RBX1 7648
FBXW4 7640
UBE2Q2 7606
UBE2J2 7481
IFITM1 7474
PDPK1 7458
DCTN4 7449
CD28 7446
NCR3 7441
BTN3A1 7410
TREM1 7370
KLRB1 7342
CD22 7331
HERC2 7326
LAIR2 7320
PSMD11 7309
FBXL5 7304
BTN2A2 7220
AREL1 7215
MTOR 7178
MKRN1 7135
CDC34 7102
ANAPC5 7097
HLA-DPA1 7053
UNKL 7015
FCGR3A 6989
LILRA5 6941
COL1A2 6930
PSME4 6905
PSMA2 6867
TREML4 6856
SIGLEC7 6848
TRAIP 6842
UBE2Q1 6827
EVL 6783
CTSS 6756
NPDC1 6748
DYNC1LI1 6729
FBXW8 6705
CTLA4 6701
PSMC6 6685
FBXL4 6668
CLEC2B 6608
FBXO41 6605
CHUK 6603
DYNC1H1 6601
CD101 6593
MAPKAP1 6583
RNF213 6533
CTSA 6514
PLCG1 6466
SEC61A1 6443
ICAM4 6428
FBXO44 6425
TPP2 6399
CARD11 6395
ITGA4 6368
AP1G1 6341
RAB7A 6317
PSMB6 6285
ULBP3 6266
DTX3L 6248
AKT2 6231
SLAMF6 6205
CTSL 6187
CD40 6167
CANX 6158
RICTOR 6152
FBXO2 6140
SEC61G 6090
CUL7 6075
KLHL20 6056
TRAF7 6037
HLA-B 5985
UBE2V2 5978
SIPA1 5970
PVR 5955
ITGAV 5900
KBTBD6 5815
RNF182 5809
RIPK2 5784
RNF14 5781
KIR2DL1 5737
PPP2R5A 5717
UBE2V1 5716
CLEC2D 5592
TUBA4A 5555
KCTD6 5517
CTSC 5493
KLHL21 5484
PSMD9 5439
CD74 5433
NFKBIB 5284
TRIM36 5275
MGRN1 5269
PIK3CA 5267
HLA-DMB 5225
ANAPC10 5142
HECTD1 5134
UBE2H 5128
BLMH 5120
TRIM69 5116
LCP2 5095
PSMD7 5071
CD274 5054
B2M 5052
CLTC 5050
RNF138 5039
FBXW5 5022
ITCH 5014
NEDD4 4997
PRKCB 4990
PSMB3 4905
PSMB7 4896
FBXL22 4881
SOS1 4874
TRIM32 4868
SIAH2 4839
PIK3R1 4837
KBTBD7 4816
UBE2E3 4814
FBXW2 4813
VCAM1 4795
CENPE 4766
FBXL12 4726
CTSH 4696
PAK2 4670
SELL 4660
ICAM2 4651
YWHAZ 4640
UBA5 4633
UBE2W 4575
AP2B1 4519
VAMP8 4508
PPP2R5C 4507
UBE2O 4506
CDC42 4492
KIF2C 4469
RNF130 4463
WWP1 4451
LAT 4394
KLC3 4365
MYLIP 4360
AP2M1 4358
ASB4 4334
UBE2K 4328
LTN1 4324
AKT3 4319
PRKACB 4309
FBXO30 4298
AP2A2 4289
CTSB 4265
PIK3R2 4257
MICB 4244
KIF18A 4221
ATG7 4220
STX4 4203
LY96 4188
UBOX5 4182
LILRA2 4168
THOP1 4161
KLHL9 4097
PSMB1 4033
PSMA5 4001
ATG14 3893
TRIM11 3890
ANAPC2 3845
PSMD14 3838
TUBB8 3806
UBE3A 3799
CUL1 3754
PTPN22 3737
CUL2 3699
THEM4 3616
LILRB2 3533
TUBB4A 3526
ACTR1B 3504
TUBA4B 3468
UBE2F 3463
LNX1 3354
TUBB4B 3352
CD300LF 3272
TRIM71 3234
KLHL22 3214
CXADR 3197
HERC5 3192
GAN 3179
UFL1 3171
HLA-C 3151
ITPR2 3140
FBXL16 3139
CD300E 3075
DYNC1I2 3054
HLA-DMA 3012
PSMD12 3007
LRSAM1 2913
FBXL20 2900
AP1S3 2843
AP2S1 2832
PRKN 2779
KIF3A 2776
SIAH1 2766
SIGLEC9 2751
DCTN3 2734
SAR1B 2664
FZR1 2630
UBR2 2625
PSMA4 2616
HLA-DQB1 2592
PSME1 2536
MRC2 2534
SIGLEC10 2505
PPIA 2496
ERAP2 2472
KIF4B 2433
ZAP70 2429
KLC1 2423
CSK 2358
AP2A1 2334
BTRC 2310
KLHL3 2282
ANAPC13 2274
CD200R1 2267
FBXO21 2238
CD36 2202
AP1B1 2122
TLR2 2095
PPP3R1 2053
INPP5D 1988
PRKCQ 1984
SEC13 1952
SNAP23 1931
HERC3 1910
RNF115 1860
RILP 1859
ZBTB16 1847
RPS27A 1837
PPP2CA 1817
RNF144B 1802
CDC27 1790
KLHL11 1742
TRIM39 1739
ITPR1 1737
FBXL8 1733
PRKACG 1714
CD8A 1712
UBE3C 1683
KIF22 1643
CD19 1628
KLRG1 1596
HLA-E 1592
PIK3CB 1590
NFATC1 1585
UBE2J1 1561
PPP3CA 1542
KEAP1 1532
FBXO17 1427
RASGRP1 1421
SOCS1 1403
SIGLEC6 1400
COL2A1 1379
GRB2 1328
TIRAP 1239
FYB1 1190
SIGLEC8 1114
ULBP1 1101
TUBB3 1052
PJA2 1045
LCK 1044
HECTD3 1037
ITPR3 994
ASB14 968
NFATC3 922
PSMD1 886
SEC61A2 874
RNF111 856
VHL 843
TRIM50 807
HCST 803
COL3A1 796
HSPA5 758
RNF123 749
ZNRF2 713
FBXO11 692
CDC23 687
ANAPC1 671
RASGRP3 589
PSMD6 572
PSMC3 570
RAP1GAP2 554
SRC 550
PSMB2 533
CUL5 463
PSMD8 460
CAPZB 419
FBXO31 392
PAG1 382
PSMA3 337
LONRF1 308
ICAM3 256
FBXL13 213
FBXL18 176
PSMD5 170
UBE2D1 159
CUL3 113
ACTR10 106
JAML 44
FKBP1A 34
CCNF 32
TLR4 21
FBXO10 -8
STIM1 -10
UBE2L6 -57
SKP2 -107
FBXO22 -157
KLHL42 -167
KIFAP3 -241
BTBD6 -246
HLA-DQA2 -313
UBE3D -398
DYNC1I1 -433
ITGB2 -450
REL -512
SEM1 -525
SYK -533
MAP3K7 -559
COLEC12 -565
TUBB2B -595
LMO7 -599
FBXO9 -621
RAF1 -714
DZIP3 -760
FBXO6 -766
PSMA1 -810
ASB3 -833
SH2D1B -867
FBXO32 -874
PRR5 -900
KIF5B -945
HERC1 -946
PIANP -974
SIGLEC12 -975
TRIM4 -1009
ORAI2 -1035
CTSF -1071
HACE1 -1096
PRKG1 -1101
TLR1 -1161
PIK3C3 -1205
UBA6 -1222
MAP3K14 -1240
IFI30 -1272
CALM1 -1278
RNF19B -1391
PPP2R1A -1400
DNM2 -1411
NFKBIE -1434
KCTD7 -1455
RCHY1 -1470
ITGAL -1515
KIF15 -1532
TRIM37 -1547
SPTBN2 -1563
FBXO4 -1583
UBE2G2 -1669
NCR3LG1 -1681
DNM3 -1706
UBE2D2 -1754
NCF2 -1761
SOCS3 -1804
RBBP6 -1819
LNPEP -1830
PAK1 -1880
CTSO -1918
UBE2M -1931
LYN -1937
ARIH2 -1950
TRIB3 -1981
DCTN2 -2057
UBAC1 -2072
CTSV -2142
UBE4A -2167
PSME2 -2199
PIK3R4 -2201
TAP2 -2202
SH3GL2 -2230
RBCK1 -2247
HLA-DOA -2248
MAP3K8 -2258
KIF20A -2271
DCTN5 -2292
XDH -2309
ASB15 -2389
FBXO15 -2403
HERC6 -2404
PSMD4 -2411
KIF26A -2416
PPL -2482
HLA-DOB -2511
LILRA3 -2516
TLR6 -2556
SEC24D -2584
FBXL7 -2746
TUBA1C -2761
HLA-A -2765
BTNL8 -2775
VAV1 -2815
BTBD1 -2865
UBE2G1 -2932
FBXW11 -2934
MICA -2948
BLK -3016
FBXW12 -3055
HERC4 -3066
TUBB6 -3105
GLMN -3200
ELOC -3244
DYNLL1 -3248
RAPGEF4 -3281
NCK1 -3408
NCR1 -3413
FGB -3453
UBE2E1 -3458
BTN2A1 -3483
ERAP1 -3521
SEC61B -3524
FBXO27 -3554
RAP1B -3556
BECN1 -3611
RNF114 -3615
COL1A1 -3665
KLHL5 -3728
TAB2 -3767
IKBKB -3825
CD1D -3849
FBXO7 -3923
TUBA1B -3969
PIK3CD -3974
FGG -3975
CAPZA1 -3984
PIK3AP1 -4001
UBE3B -4007
YES1 -4046
CD34 -4073
ANAPC11 -4140
PPP2R5E -4190
FBXW7 -4192
PTPRC -4204
DYNC1LI2 -4243
KIF23 -4270
ASB18 -4321
RNF25 -4325
SH3RF1 -4329
PSMB5 -4359
CD81 -4360
KLHL25 -4421
RNF217 -4457
AHCYL1 -4527
UBE2D4 -4542
SMURF1 -4602
RACGAP1 -4730
KRAS -4743
DCTN6 -4777
PSMD3 -4790
PSMD2 -4823
RNF41 -4837
SEC22B -4858
RNF4 -4863
BTNL2 -4918
AP1M1 -4931
WSB1 -4947
PSMA7 -4955
TRIP12 -4956
PSMA8 -4966
SEC31A -4974
ELOB -5019
KIF11 -5022
ASB8 -5033
PSMB8 -5035
RAP1A -5040
KLC2 -5044
SEC24A -5095
RNF220 -5119
AP1M2 -5138
CRTAM -5160
SIGLEC11 -5254
TUBAL3 -5273
TUBA1A -5328
LILRB3 -5333
MADCAM1 -5342
NEDD4L -5357
ASB2 -5404
SPSB2 -5435
PSMB9 -5459
ANAPC7 -5464
UBE2D3 -5466
KIR3DL2 -5467
CDC26 -5475
PPP3CB -5477
RASGRP2 -5539
UBE2R2 -5556
OSCAR -5566
AKT1 -5586
RNF19A -5588
UBR4 -5626
FBXL19 -5665
PTEN -5671
HLA-DQB2 -5718
MALT1 -5777
PSMA6 -5784
STUB1 -5809
ASB1 -5815
PSMC2 -5834
PSMC4 -5874
KLRC1 -5916
C3 -5985
ANAPC4 -6057
UBE2L3 -6065
FBXL15 -6090
SPSB1 -6117
SIGLEC5 -6168
HMGB1 -6344
ASB16 -6345
SPSB4 -6362
CD8B -6376
TUBB2A -6393
NFATC2 -6394
YWHAB -6461
CLTA -6520
NFKBIA -6526
UBB -6535
LRRC41 -6589
ITK -6661
CD4 -6717
CYBA -6734
ASB13 -6776
HLA-DRB1 -6804
CAPZA2 -6878
PSMC1 -6897
CALR -6910
PIK3R3 -7035
TAPBP -7039
BCL10 -7068
ORAI1 -7107
ACTR1A -7157
SLAMF7 -7175
PRKACA -7200
TAP1 -7222
KIF2B -7248
KIF2A -7265
LGMN -7270
UBE2S -7305
UBC -7308
VAMP3 -7336
KLC4 -7349
DYNLL2 -7375
FBXL14 -7389
SEC23A -7400
TRAT1 -7422
HLA-G -7447
RELA -7456
PSME3 -7475
UBE2N -7482
PSMB4 -7626
PTPN6 -7632
HECW2 -7655
CD300LD -7703
ENAH -7705
PSMC5 -7743
RAPGEF3 -7768
TRIM41 -7817
KBTBD8 -7930
DET1 -7948
NFKB1 -8019
PTPRJ -8030
BTNL9 -8046
NRAS -8056
TUBA8 -8057
UBA52 -8101
ICAM5 -8125
PLCG2 -8157
FYN -8164
MYD88 -8168
UBE2B -8180
HLA-DRB5 -8197
CBLB -8211
KLHL41 -8213
MLST8 -8255
RAC1 -8281
KIR2DL4 -8316
KLRD1 -8333
ARF1 -8378
CD14 -8469
CD1A -8476
MEX3C -8486
CD300A -8491
ASB17 -8560
CD300LG -8589
NCR2 -8594
NCF4 -8667
NPEPPS -8685
SEC24C -8716
ICAM1 -8748
FBXL3 -8756
TUBA3D -8798
KIF5A -8814
CD96 -8821
CDC20 -8838
RNF6 -8915
TRIM9 -8972
KIF3C -8977
OSBPL1A -9016
ITGB1 -9031
DNM1 -9071
PDCD1 -9112
UBE2E2 -9198
UBE2C -9239
ITGB5 -9313
LAG3 -9418
DCTN1 -9474
RNF126 -9548
HECTD2 -9617
KLRK1 -9630
CD80 -9716
UBA3 -9753
BLNK -9775
CD207 -9825
CD86 -9840
TRPC1 -9856
CD226 -9872
CDC16 -9923
COL17A1 -9936
CD300C -10034
SKP1 -10072
PDIA3 -10146
PSMB10 -10166
TYROBP -10190
RNF7 -10204
ASB6 -10213
SIGLEC1 -10248
FBXW10 -10255
CTSD -10276
FBXO40 -10295
TUBA3E -10348
KIF3B -10441
BTN3A3 -10483
HRAS -10556
MIB2 -10647
S100A8 -10656
LILRA1 -10680
RAP1GAP -10685
CLEC4G -10692
VASP -10726
NECTIN2 -10743
DAPP1 -10769
LILRB5 -10774
PILRA -10814
TRIM63 -10860
UBA7 -10870
PTPN11 -10878
PPP2CB -10912
CDH1 -10913
RAET1E -11030
UBE2Z -11089
ICOS -11202
CD209 -11237
UBE2U -11257
LILRB4 -11267
CD1C -11276
TREML1 -11316
LILRB1 -11358
PSMB11 -11624
S100A1 -11637
CD300LB -11801
ASB10 -11835
CAPZA3 -11852
CTSE -11963
TREM2 -11972


REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
1476
set REACTOME_TRANSCRIPTIONAL_REGULATION_OF_GRANULOPOIESIS
setSize 83
pANOVA 0.0112
s.dist 0.161
p.adjustANOVA 0.383



Top enriched genes

Top 20 genes
GeneID Gene Rank
H3C1 9085.0
H2AZ2 8952.0
H2BC17 8591.0
H4C12 8556.0
IL6R 8529.0
DEK 8262.0
H4C5 8212.0
LEF1 8081.0
TFDP2 7789.0
SPI1 7554.0
H2BC9 7299.5
H3C7 7299.5
STAT3 6634.0
TFDP1 6358.0
H4C3 6009.0
H2BC12 5854.0
H2AC4 5676.0
FLI1 5627.0
H2AC20 5583.0
H3C8 5547.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H3C1 9085.0
H2AZ2 8952.0
H2BC17 8591.0
H4C12 8556.0
IL6R 8529.0
DEK 8262.0
H4C5 8212.0
LEF1 8081.0
TFDP2 7789.0
SPI1 7554.0
H2BC9 7299.5
H3C7 7299.5
STAT3 6634.0
TFDP1 6358.0
H4C3 6009.0
H2BC12 5854.0
H2AC4 5676.0
FLI1 5627.0
H2AC20 5583.0
H3C8 5547.0
KLF5 5494.0
H4C9 5306.0
MYB 5194.0
H4C6 4702.0
H3-3A 4158.0
RARA 4076.0
H2BC13 4070.0
CDKN1A 3835.0
H2AC7 3829.5
H2BC7 3829.5
TAL1 3671.0
H2BC6 3659.0
CEBPE 3302.0
H2AC18 3107.5
H2AC19 3107.5
H4C16 2844.0
CEBPB 2627.0
H4C1 2332.0
PML 2311.0
H3C11 2270.0
CDK2 2115.0
H2AJ 2047.0
H3C6 1887.0
H2BC4 1347.0
RXRA 1224.0
H3C2 1183.0
H2AC6 949.0
H2BC21 723.0
RUNX1 702.0
E2F1 271.0
GATA2 128.0
EP300 15.0
H2BC5 -9.0
H3C4 -374.0
H2BC10 -1032.0
H2BC15 -1414.0
H2AX -1653.0
H4C13 -2630.0
H4C4 -2649.0
H4C8 -2728.0
H2BC3 -2958.0
CBFB -3194.0
H4C11 -3485.0
MYC -4660.0
H3C3 -5940.0
H2BC1 -6416.0
KMT2A -6565.0
H2BC11 -6780.0
H2BC26 -6814.0
H4C2 -7011.0
GFI1 -7186.0
H2AZ1 -7369.0
CSF3R -7875.0
H3-3B -7982.0
CREB1 -8293.0
CEBPA -8555.0
CDK4 -8679.0
H2AC8 -8778.0
H2BC8 -9079.0
H2BC14 -9980.0
H3C10 -10013.0
H2AC14 -10060.0
H3C12 -10932.0


REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 0.0115
s.dist -0.115
p.adjustANOVA 0.385



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB11 -11624.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
PSMB10 -10166.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
MAGOH -9442.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB11 -11624.0
RPL29 -11475.0
RPL18 -11061.0
RPLP2 -11033.0
RPL23 -10766.0
RPL13A -10708.5
RPL27 -10705.0
RPL21 -10618.0
RPS15A -10613.0
RPS10 -10288.0
RPS15 -10280.0
RPL3 -10246.0
PSMB10 -10166.0
RPL10A -10119.0
RPL36 -10058.0
RPS28 -9918.0
RPL4 -9917.0
RPS8 -9901.0
RPL7 -9769.0
MAGOH -9442.0
RPL37 -9383.0
RPL38 -9338.0
EIF4G1 -9280.0
RPL18A -9270.0
RPL14 -9085.0
FAU -8524.0
RPS2 -8500.0
RPS3A -8441.0
RPS18 -8407.0
RPL8 -8322.0
RPS12 -8301.0
UBA52 -8101.0
RPL35A -7809.0
SLIT1 -7797.0
RPS25 -7758.0
PSMC5 -7743.0
PSMB4 -7626.0
PSME3 -7475.0
RBM8A -7442.0
UBC -7308.0
RPS5 -7280.0
RPS13 -7029.0
RPS6 -6939.0
PSMC1 -6897.0
RPL13 -6617.0
UBB -6535.0
RPS20 -6260.0
PSMC4 -5874.0
PSMC2 -5834.0
PSMA6 -5784.0
RPL41 -5634.0
PSMB9 -5459.0
RPS21 -5458.0
RPL23A -5311.0
PABPC1 -5303.0
LHX3 -5157.0
RPS24 -5072.0
PSMB8 -5035.0
ELOB -5019.0
RPL39L -5003.0
PSMA8 -4966.0
PSMA7 -4955.0
UPF2 -4889.0
PSMD2 -4823.0
RPL22L1 -4795.0
PSMD3 -4790.0
RPS23 -4737.0
RPL7A -4508.0
PSMB5 -4359.0
ETF1 -4193.0
RPL3L -4049.0
RPL6 -4047.0
GSPT1 -4015.0
ROBO3 -3980.0
RPLP0 -3936.0
RPL36AL -3855.5
RPL12 -3714.0
LHX9 -3681.0
LHX2 -3582.0
RPL30 -3513.0
SLIT2 -3421.0
ELOC -3244.0
CASC3 -3191.0
RPL35 -3180.0
RPL24 -2999.0
RPS7 -2847.0
RPSA -2801.0
RPL9 -2423.0
PSMD4 -2411.0
RPS27L -2334.0
NCBP1 -2261.0
PSME2 -2199.0
RPS26 -2128.0
RPL28 -2101.0
LHX4 -1962.0
RPS3 -1606.0
RPL22 -1193.0
RPS29 -1088.0
RPL17 -837.0
PSMA1 -810.0
RPL5 -544.0
SEM1 -525.0
ROBO1 -355.0
RNPS1 -298.0
RPS11 -225.0
RPL26 -28.0
MSI1 98.0
PSMD5 170.0
MAGOHB 192.0
PSMA3 337.0
RPL27A 454.0
PSMD8 460.0
PSMB2 533.0
PSMC3 570.0
PSMD6 572.0
PSMD1 886.0
RPL19 1027.0
RPL11 1163.0
RPS16 1311.0
ZSWIM8 1621.0
RPS27A 1837.0
NCBP2 2289.0
ROBO2 2377.0
PSME1 2536.0
PSMA4 2616.0
RPLP1 2863.0
PSMD12 3007.0
EIF4A3 3582.0
CUL2 3699.0
PSMD14 3838.0
RPL34 3847.0
PSMA5 4001.0
PSMB1 4033.0
ISL1 4079.0
RPS9 4427.0
LDB1 4472.0
RPL37A 4707.0
PSMB7 4896.0
PSMB3 4905.0
PSMD7 5071.0
RPL15 5290.0
PSMD9 5439.0
RPL26L1 5864.0
DAG1 6247.0
PSMB6 6285.0
PSMC6 6685.0
PSMA2 6867.0
PSME4 6905.0
RPL32 7009.0
RPS19 7158.0
PSMD11 7309.0
RBX1 7648.0
RPS27 7711.0
PSMF1 7714.0
UPF3A 7923.0
RPS14 8094.0
USP33 8337.0
RPL31 8401.0
PSMD13 8524.0
HOXA2 8666.0
RPL10L 9197.0


REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS

REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS
385
set REACTOME_METABOLISM_OF_ANGIOTENSINOGEN_TO_ANGIOTENSINS
setSize 16
pANOVA 0.0122
s.dist -0.362
p.adjustANOVA 0.396



Top enriched genes

Top 20 genes
GeneID Gene Rank
CPA3 -10737
AGT -10682
CPB1 -10501
ACE -10469
CTSD -10276
ANPEP -10097
CES1 -8497
CPB2 -5274
CMA1 -4997
MME -4127
CTSG -3799
CTSZ -1929
ENPEP -957
AOPEP -181
REN 707
GZMH 9656

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CPA3 -10737
AGT -10682
CPB1 -10501
ACE -10469
CTSD -10276
ANPEP -10097
CES1 -8497
CPB2 -5274
CMA1 -4997
MME -4127
CTSG -3799
CTSZ -1929
ENPEP -957
AOPEP -181
REN 707
GZMH 9656


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report