Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2024-01-18
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
| x | |
|---|---|
| A1BG | -0.0036275 |
| A1BG-AS1 | -0.0025847 |
| A1CF | 0.0086162 |
| A2M | -0.0036205 |
| A2M-AS1 | 0.0167440 |
| A2ML1 | 0.0082655 |
Here are some metrics about the input data profile:
| Profile metrics | |
|---|---|
| num_genesets | 1654 |
| num_genes_in_profile | 22007 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 10383 |
| num_profile_genes_not_in_sets | 11624 |
Here is a plot of the input profiles. Note the dynamic ranges.
Here is the contour plot of the profile including all detected genes.
Input genesets
Here are some metrics about the gene sets used:
GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt| Gene sets metrics | |
|---|---|
| num_genesets | 1654 |
| num_genesets_excluded | 365 |
| num_genesets_included | 1289 |
Differential pathway expression
Interactive enrichment scatterplot
Significance is calculated by -log10(p-value). All points shown are
FDR<0.05.
Significance is calculated by -log10(p-value). Top N sets shown
irrespective of FDR.
Results table
Top N= 50 gene sets
## Warning in kable_styling(., "hover", full_width = FALSE): Please specify format
## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 1.61e-19 | -0.1470 | 2.65e-16 |
| REACTOME SENSORY PERCEPTION | 555 | 2.08e-14 | 0.1900 | 1.71e-11 |
| REACTOME CELL CYCLE | 666 | 2.09e-12 | -0.1600 | 9.44e-10 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 2.30e-12 | 0.2190 | 9.44e-10 |
| REACTOME CELL CYCLE MITOTIC | 539 | 4.66e-11 | -0.1660 | 1.53e-08 |
| REACTOME M PHASE | 398 | 6.00e-09 | -0.1700 | 1.64e-06 |
| REACTOME KERATINIZATION | 210 | 1.21e-06 | 0.1940 | 2.84e-04 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 5.41e-06 | -0.1750 | 1.11e-03 |
| REACTOME METABOLISM OF RNA | 675 | 1.76e-05 | -0.0969 | 2.99e-03 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 1.82e-05 | -0.1530 | 2.99e-03 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 2.71e-05 | 0.2170 | 3.96e-03 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 2.96e-05 | -0.1740 | 3.96e-03 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 3.14e-05 | -0.1440 | 3.96e-03 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 3.51e-05 | -0.0670 | 4.12e-03 |
| REACTOME MRNA SPLICING | 197 | 4.45e-05 | -0.1690 | 4.65e-03 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 4.53e-05 | -0.1700 | 4.65e-03 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 5.99e-05 | 0.1520 | 5.78e-03 |
| REACTOME SUMOYLATION | 179 | 6.37e-05 | -0.1730 | 5.81e-03 |
| REACTOME DNA REPAIR | 321 | 9.21e-05 | -0.1270 | 7.96e-03 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 1.11e-04 | 0.3410 | 9.10e-03 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 1.18e-04 | -0.4000 | 9.20e-03 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 1.35e-04 | 0.1530 | 1.01e-02 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 1.76e-04 | 0.0834 | 1.26e-02 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 1.95e-04 | -0.2500 | 1.33e-02 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 2.18e-04 | -0.1290 | 1.43e-02 |
| REACTOME CELLULAR SENESCENCE | 189 | 2.93e-04 | -0.1530 | 1.85e-02 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 3.48e-04 | -0.2840 | 2.12e-02 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 3.62e-04 | -0.1520 | 2.12e-02 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 4.65e-04 | -0.1850 | 2.63e-02 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 5.19e-04 | 0.2300 | 2.84e-02 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 5.49e-04 | 0.2690 | 2.89e-02 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 5.64e-04 | 0.1170 | 2.89e-02 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 7.44e-04 | -0.2050 | 3.70e-02 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 7.68e-04 | 0.1760 | 3.71e-02 |
| REACTOME TRNA PROCESSING | 105 | 8.20e-04 | -0.1890 | 3.85e-02 |
| REACTOME DEUBIQUITINATION | 260 | 8.65e-04 | -0.1200 | 3.95e-02 |
| REACTOME MITOTIC PROPHASE | 134 | 8.98e-04 | -0.1660 | 3.99e-02 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 9.53e-04 | -0.4630 | 4.07e-02 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 9.72e-04 | -0.0695 | 4.07e-02 |
| REACTOME MUSCLE CONTRACTION | 197 | 9.92e-04 | 0.1360 | 4.07e-02 |
| REACTOME SIGNALING BY GPCR | 673 | 1.22e-03 | 0.0731 | 4.89e-02 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 1.29e-03 | -0.1330 | 4.97e-02 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 1.30e-03 | -0.1460 | 4.97e-02 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 1.52e-03 | -0.1730 | 5.67e-02 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 1.62e-03 | -0.4870 | 5.70e-02 |
| REACTOME CILIUM ASSEMBLY | 190 | 1.63e-03 | -0.1330 | 5.70e-02 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 1.64e-03 | -0.2840 | 5.70e-02 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 1.66e-03 | 0.1810 | 5.70e-02 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 1.82e-03 | -0.1140 | 6.04e-02 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.84e-03 | -0.2040 | 6.04e-02 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pANOVA | s.dist | p.adjustANOVA |
|---|---|---|---|---|
| REACTOME RNA POLYMERASE II TRANSCRIPTION | 1336 | 1.61e-19 | -0.147000 | 2.65e-16 |
| REACTOME SENSORY PERCEPTION | 555 | 2.08e-14 | 0.190000 | 1.71e-11 |
| REACTOME CELL CYCLE | 666 | 2.09e-12 | -0.160000 | 9.44e-10 |
| REACTOME OLFACTORY SIGNALING PATHWAY | 348 | 2.30e-12 | 0.219000 | 9.44e-10 |
| REACTOME CELL CYCLE MITOTIC | 539 | 4.66e-11 | -0.166000 | 1.53e-08 |
| REACTOME M PHASE | 398 | 6.00e-09 | -0.170000 | 1.64e-06 |
| REACTOME KERATINIZATION | 210 | 1.21e-06 | 0.194000 | 2.84e-04 |
| REACTOME MITOTIC METAPHASE AND ANAPHASE | 228 | 5.41e-06 | -0.175000 | 1.11e-03 |
| REACTOME METABOLISM OF RNA | 675 | 1.76e-05 | -0.096900 | 2.99e-03 |
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 263 | 1.82e-05 | -0.153000 | 2.99e-03 |
| REACTOME FORMATION OF THE CORNIFIED ENVELOPE | 125 | 2.71e-05 | 0.217000 | 3.96e-03 |
| REACTOME MITOTIC PROMETAPHASE | 194 | 2.96e-05 | -0.174000 | 3.96e-03 |
| REACTOME CELL CYCLE CHECKPOINTS | 284 | 3.14e-05 | -0.144000 | 3.96e-03 |
| REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION | 1356 | 3.51e-05 | -0.067000 | 4.12e-03 |
| REACTOME MRNA SPLICING | 197 | 4.45e-05 | -0.169000 | 4.65e-03 |
| REACTOME MITOTIC G2 G2 M PHASES | 194 | 4.53e-05 | -0.170000 | 4.65e-03 |
| REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | 236 | 5.99e-05 | 0.152000 | 5.78e-03 |
| REACTOME SUMOYLATION | 179 | 6.37e-05 | -0.173000 | 5.81e-03 |
| REACTOME DNA REPAIR | 321 | 9.21e-05 | -0.127000 | 7.96e-03 |
| REACTOME INTERLEUKIN 10 SIGNALING | 43 | 1.11e-04 | 0.341000 | 9.10e-03 |
| REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III | 31 | 1.18e-04 | -0.400000 | 9.20e-03 |
| REACTOME BIOLOGICAL OXIDATIONS | 210 | 1.35e-04 | 0.153000 | 1.01e-02 |
| REACTOME TRANSPORT OF SMALL MOLECULES | 697 | 1.76e-04 | 0.083400 | 1.26e-02 |
| REACTOME NUCLEAR ENVELOPE NE REASSEMBLY | 74 | 1.95e-04 | -0.250000 | 1.33e-02 |
| REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE | 277 | 2.18e-04 | -0.129000 | 1.43e-02 |
| REACTOME CELLULAR SENESCENCE | 189 | 2.93e-04 | -0.153000 | 1.85e-02 |
| REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF | 53 | 3.48e-04 | -0.284000 | 2.12e-02 |
| REACTOME SEPARATION OF SISTER CHROMATIDS | 184 | 3.62e-04 | -0.152000 | 2.12e-02 |
| REACTOME RESOLUTION OF SISTER CHROMATID COHESION | 120 | 4.65e-04 | -0.185000 | 2.63e-02 |
| REACTOME ANTIMICROBIAL PEPTIDES | 76 | 5.19e-04 | 0.230000 | 2.84e-02 |
| REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | 55 | 5.49e-04 | 0.269000 | 2.89e-02 |
| REACTOME EXTRACELLULAR MATRIX ORGANIZATION | 291 | 5.64e-04 | 0.117000 | 2.89e-02 |
| REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | 91 | 7.44e-04 | -0.205000 | 3.70e-02 |
| REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | 122 | 7.68e-04 | 0.176000 | 3.71e-02 |
| REACTOME TRNA PROCESSING | 105 | 8.20e-04 | -0.189000 | 3.85e-02 |
| REACTOME DEUBIQUITINATION | 260 | 8.65e-04 | -0.120000 | 3.95e-02 |
| REACTOME MITOTIC PROPHASE | 134 | 8.98e-04 | -0.166000 | 3.99e-02 |
| REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF | 17 | 9.53e-04 | -0.463000 | 4.07e-02 |
| REACTOME CELLULAR RESPONSES TO STIMULI | 779 | 9.72e-04 | -0.069500 | 4.07e-02 |
| REACTOME MUSCLE CONTRACTION | 197 | 9.92e-04 | 0.136000 | 4.07e-02 |
| REACTOME SIGNALING BY GPCR | 673 | 1.22e-03 | 0.073100 | 4.89e-02 |
| REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC | 198 | 1.29e-03 | -0.133000 | 4.97e-02 |
| REACTOME DNA DOUBLE STRAND BREAK REPAIR | 162 | 1.30e-03 | -0.146000 | 4.97e-02 |
| REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS | 113 | 1.52e-03 | -0.173000 | 5.67e-02 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS | 14 | 1.62e-03 | -0.487000 | 5.70e-02 |
| REACTOME CILIUM ASSEMBLY | 190 | 1.63e-03 | -0.133000 | 5.70e-02 |
| REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP | 41 | 1.64e-03 | -0.284000 | 5.70e-02 |
| REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS | 101 | 1.66e-03 | 0.181000 | 5.70e-02 |
| REACTOME CHROMATIN MODIFYING ENZYMES | 252 | 1.82e-03 | -0.114000 | 6.04e-02 |
| REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | 78 | 1.84e-03 | -0.204000 | 6.04e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS | 36 | 2.19e-03 | -0.295000 | 7.07e-02 |
| REACTOME MITOTIC SPINDLE CHECKPOINT | 109 | 2.46e-03 | -0.168000 | 7.77e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY TP53 | 351 | 2.79e-03 | -0.092900 | 8.59e-02 |
| REACTOME POLO LIKE KINASE MEDIATED EVENTS | 16 | 2.87e-03 | -0.430000 | 8.59e-02 |
| REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 | 32 | 2.88e-03 | -0.304000 | 8.59e-02 |
| REACTOME UB SPECIFIC PROCESSING PROTEASES | 187 | 3.19e-03 | -0.125000 | 9.25e-02 |
| REACTOME HCMV INFECTION | 152 | 3.21e-03 | -0.138000 | 9.25e-02 |
| REACTOME MEMBRANE TRAFFICKING | 603 | 3.43e-03 | -0.069800 | 9.70e-02 |
| REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND | 21 | 3.52e-03 | 0.368000 | 9.79e-02 |
| REACTOME G2 M CHECKPOINTS | 162 | 3.58e-03 | -0.133000 | 9.79e-02 |
| REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION | 14 | 3.64e-03 | -0.449000 | 9.79e-02 |
| REACTOME HATS ACETYLATE HISTONES | 129 | 4.08e-03 | -0.146000 | 1.08e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS | 8 | 4.42e-03 | -0.581000 | 1.15e-01 |
| REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS | 16 | 4.50e-03 | 0.410000 | 1.15e-01 |
| REACTOME TRANSPORT OF ORGANIC ANIONS | 10 | 4.86e-03 | 0.514000 | 1.22e-01 |
| REACTOME CARDIAC CONDUCTION | 125 | 4.91e-03 | 0.146000 | 1.22e-01 |
| REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX | 39 | 5.04e-03 | -0.259000 | 1.22e-01 |
| REACTOME PTEN REGULATION | 135 | 5.06e-03 | -0.140000 | 1.22e-01 |
| REACTOME HOMOLOGY DIRECTED REPAIR | 132 | 5.11e-03 | -0.141000 | 1.22e-01 |
| REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | 30 | 5.30e-03 | 0.294000 | 1.24e-01 |
| REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT | 101 | 5.70e-03 | -0.159000 | 1.32e-01 |
| REACTOME TRNA PROCESSING IN THE NUCLEUS | 58 | 6.14e-03 | -0.208000 | 1.40e-01 |
| REACTOME RHOV GTPASE CYCLE | 36 | 6.40e-03 | -0.263000 | 1.42e-01 |
| REACTOME CREATION OF C4 AND C2 ACTIVATORS | 14 | 6.45e-03 | 0.420000 | 1.42e-01 |
| REACTOME NONHOMOLOGOUS END JOINING NHEJ | 64 | 6.59e-03 | -0.196000 | 1.42e-01 |
| REACTOME INTEGRIN CELL SURFACE INTERACTIONS | 83 | 6.68e-03 | 0.172000 | 1.42e-01 |
| REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS | 74 | 6.71e-03 | -0.182000 | 1.42e-01 |
| REACTOME MET PROMOTES CELL MOTILITY | 41 | 6.74e-03 | 0.245000 | 1.42e-01 |
| REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 7.16e-03 | 0.401000 | 1.48e-01 |
| REACTOME NUCLEAR ENVELOPE BREAKDOWN | 52 | 7.29e-03 | -0.215000 | 1.48e-01 |
| REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING | 45 | 7.37e-03 | 0.231000 | 1.48e-01 |
| REACTOME COLLAGEN FORMATION | 88 | 7.39e-03 | 0.165000 | 1.48e-01 |
| REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS | 25 | 8.00e-03 | -0.306000 | 1.58e-01 |
| REACTOME RHO GTPASES ACTIVATE IQGAPS | 31 | 9.61e-03 | -0.269000 | 1.83e-01 |
| REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | 134 | 9.67e-03 | 0.129000 | 1.83e-01 |
| REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION | 28 | 9.70e-03 | 0.282000 | 1.83e-01 |
| REACTOME DNA DAMAGE REVERSAL | 8 | 9.72e-03 | -0.528000 | 1.83e-01 |
| REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM | 21 | 9.99e-03 | -0.325000 | 1.86e-01 |
| REACTOME GOLGI TO ER RETROGRADE TRANSPORT | 132 | 1.03e-02 | -0.129000 | 1.86e-01 |
| REACTOME REGULATION OF BETA CELL DEVELOPMENT | 41 | 1.03e-02 | -0.232000 | 1.86e-01 |
| REACTOME G ALPHA I SIGNALLING EVENTS | 304 | 1.03e-02 | 0.085500 | 1.86e-01 |
| REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS | 68 | 1.06e-02 | -0.179000 | 1.88e-01 |
| REACTOME XENOBIOTICS | 22 | 1.08e-02 | 0.314000 | 1.88e-01 |
| REACTOME ASPARAGINE N LINKED GLYCOSYLATION | 299 | 1.09e-02 | -0.085600 | 1.88e-01 |
| REACTOME HCMV EARLY EVENTS | 128 | 1.10e-02 | -0.130000 | 1.88e-01 |
| REACTOME DISEASES OF PROGRAMMED CELL DEATH | 96 | 1.10e-02 | -0.150000 | 1.88e-01 |
| REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES | 65 | 1.11e-02 | 0.182000 | 1.88e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 | 229 | 1.16e-02 | -0.096800 | 1.94e-01 |
| REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT | 152 | 1.17e-02 | -0.118000 | 1.94e-01 |
| REACTOME COLLAGEN CHAIN TRIMERIZATION | 42 | 1.23e-02 | 0.223000 | 2.00e-01 |
| REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK | 47 | 1.24e-02 | -0.211000 | 2.00e-01 |
| REACTOME PKMTS METHYLATE HISTONE LYSINES | 64 | 1.24e-02 | -0.181000 | 2.00e-01 |
| REACTOME VESICLE MEDIATED TRANSPORT | 642 | 1.27e-02 | -0.057600 | 2.03e-01 |
| REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT | 222 | 1.30e-02 | -0.096800 | 2.05e-01 |
| REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 98 | 1.32e-02 | -0.145000 | 2.05e-01 |
| REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND | 55 | 1.32e-02 | -0.193000 | 2.05e-01 |
| REACTOME COMPLEMENT CASCADE | 54 | 1.34e-02 | 0.195000 | 2.05e-01 |
| REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX | 85 | 1.35e-02 | -0.155000 | 2.05e-01 |
| REACTOME MET ACTIVATES PTK2 SIGNALING | 30 | 1.44e-02 | 0.258000 | 2.17e-01 |
| REACTOME COLLAGEN DEGRADATION | 61 | 1.46e-02 | 0.181000 | 2.17e-01 |
| REACTOME G2 M DNA DAMAGE CHECKPOINT | 90 | 1.49e-02 | -0.149000 | 2.20e-01 |
| REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION | 138 | 1.54e-02 | -0.119000 | 2.25e-01 |
| REACTOME RHO GTPASES ACTIVATE FORMINS | 136 | 1.64e-02 | -0.119000 | 2.38e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | 81 | 1.66e-02 | -0.154000 | 2.39e-01 |
| REACTOME PROPIONYL COA CATABOLISM | 5 | 1.69e-02 | -0.617000 | 2.41e-01 |
| REACTOME ION HOMEOSTASIS | 52 | 1.70e-02 | 0.191000 | 2.41e-01 |
| REACTOME SIGNALING BY MET | 78 | 1.72e-02 | 0.156000 | 2.42e-01 |
| REACTOME FERTILIZATION | 26 | 1.75e-02 | 0.269000 | 2.42e-01 |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 129 | 1.75e-02 | 0.121000 | 2.42e-01 |
| REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA | 115 | 1.82e-02 | -0.127000 | 2.45e-01 |
| REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | 26 | 1.86e-02 | -0.267000 | 2.45e-01 |
| REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | 23 | 1.86e-02 | -0.284000 | 2.45e-01 |
| REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 58 | 1.87e-02 | -0.179000 | 2.45e-01 |
| REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT | 159 | 1.88e-02 | -0.108000 | 2.45e-01 |
| REACTOME PHASE 0 RAPID DEPOLARISATION | 31 | 1.88e-02 | 0.244000 | 2.45e-01 |
| REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE | 17 | 1.88e-02 | 0.329000 | 2.45e-01 |
| REACTOME DEFECTS IN COBALAMIN B12 METABOLISM | 13 | 1.92e-02 | -0.375000 | 2.48e-01 |
| REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | 82 | 1.94e-02 | 0.149000 | 2.49e-01 |
| REACTOME TYPE I HEMIDESMOSOME ASSEMBLY | 11 | 2.02e-02 | 0.404000 | 2.58e-01 |
| REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS | 93 | 2.06e-02 | -0.139000 | 2.60e-01 |
| REACTOME DRUG ADME | 103 | 2.08e-02 | 0.132000 | 2.60e-01 |
| REACTOME SENSORY PROCESSING OF SOUND | 72 | 2.09e-02 | 0.157000 | 2.60e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX | 19 | 2.16e-02 | -0.304000 | 2.63e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY VENTX | 41 | 2.19e-02 | -0.207000 | 2.63e-01 |
| REACTOME HIV INFECTION | 223 | 2.21e-02 | -0.088900 | 2.63e-01 |
| REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS | 11 | 2.22e-02 | -0.398000 | 2.63e-01 |
| REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES | 59 | 2.24e-02 | 0.172000 | 2.63e-01 |
| REACTOME SUMOYLATION OF RNA BINDING PROTEINS | 47 | 2.24e-02 | -0.192000 | 2.63e-01 |
| REACTOME INTEGRIN SIGNALING | 27 | 2.25e-02 | 0.254000 | 2.63e-01 |
| REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION | 90 | 2.27e-02 | -0.139000 | 2.63e-01 |
| REACTOME CHAPERONE MEDIATED AUTOPHAGY | 20 | 2.29e-02 | 0.294000 | 2.63e-01 |
| REACTOME PHASE II CONJUGATION OF COMPOUNDS | 102 | 2.29e-02 | 0.130000 | 2.63e-01 |
| REACTOME SIGNALING BY INTERLEUKINS | 444 | 2.32e-02 | 0.062900 | 2.63e-01 |
| REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION | 24 | 2.33e-02 | -0.268000 | 2.63e-01 |
| REACTOME HEME DEGRADATION | 15 | 2.34e-02 | 0.338000 | 2.63e-01 |
| REACTOME SENSORY PERCEPTION OF TASTE | 47 | 2.35e-02 | 0.191000 | 2.63e-01 |
| REACTOME GLUTATHIONE CONJUGATION | 33 | 2.35e-02 | 0.228000 | 2.63e-01 |
| REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE | 93 | 2.37e-02 | -0.136000 | 2.63e-01 |
| REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE | 20 | 2.41e-02 | -0.291000 | 2.65e-01 |
| REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION | 84 | 2.42e-02 | -0.142000 | 2.65e-01 |
| REACTOME IRAK4 DEFICIENCY TLR2 4 | 17 | 2.45e-02 | 0.315000 | 2.65e-01 |
| REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 | 679 | 2.46e-02 | -0.050600 | 2.65e-01 |
| REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING | 12 | 2.51e-02 | 0.373000 | 2.68e-01 |
| REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION | 18 | 2.51e-02 | -0.305000 | 2.68e-01 |
| REACTOME INNATE IMMUNE SYSTEM | 1002 | 2.54e-02 | 0.041700 | 2.68e-01 |
| REACTOME ORGANIC ANION TRANSPORT | 5 | 2.55e-02 | 0.577000 | 2.68e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS | 29 | 2.56e-02 | -0.239000 | 2.68e-01 |
| REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX | 14 | 2.66e-02 | -0.342000 | 2.71e-01 |
| REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | 183 | 2.69e-02 | -0.094800 | 2.71e-01 |
| REACTOME G ALPHA Q SIGNALLING EVENTS | 206 | 2.70e-02 | 0.089400 | 2.71e-01 |
| REACTOME RORA ACTIVATES GENE EXPRESSION | 17 | 2.73e-02 | -0.309000 | 2.71e-01 |
| REACTOME OPIOID SIGNALLING | 89 | 2.75e-02 | 0.135000 | 2.71e-01 |
| REACTOME HCMV LATE EVENTS | 110 | 2.77e-02 | -0.121000 | 2.71e-01 |
| REACTOME PLATELET AGGREGATION PLUG FORMATION | 39 | 2.78e-02 | 0.204000 | 2.71e-01 |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 78 | 2.81e-02 | -0.144000 | 2.71e-01 |
| REACTOME G PROTEIN ACTIVATION | 24 | 2.81e-02 | 0.259000 | 2.71e-01 |
| REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION | 145 | 2.83e-02 | -0.105000 | 2.71e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 | 25 | 2.85e-02 | 0.253000 | 2.71e-01 |
| REACTOME CELL CELL COMMUNICATION | 126 | 2.86e-02 | 0.113000 | 2.71e-01 |
| REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS | 5 | 2.90e-02 | -0.564000 | 2.71e-01 |
| REACTOME AURKA ACTIVATION BY TPX2 | 69 | 2.90e-02 | -0.152000 | 2.71e-01 |
| REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS | 66 | 2.91e-02 | 0.155000 | 2.71e-01 |
| REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | 15 | 2.92e-02 | 0.325000 | 2.71e-01 |
| REACTOME RHO GTPASE EFFECTORS | 305 | 2.93e-02 | -0.072500 | 2.71e-01 |
| REACTOME SIGNALING BY PTK6 | 54 | 2.94e-02 | 0.171000 | 2.71e-01 |
| REACTOME CELL JUNCTION ORGANIZATION | 89 | 2.94e-02 | 0.134000 | 2.71e-01 |
| REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS | 55 | 2.94e-02 | 0.170000 | 2.71e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION | 29 | 2.97e-02 | -0.233000 | 2.71e-01 |
| REACTOME ECM PROTEOGLYCANS | 73 | 2.98e-02 | 0.147000 | 2.71e-01 |
| REACTOME PYRIMIDINE SALVAGE | 10 | 2.99e-02 | 0.396000 | 2.71e-01 |
| REACTOME SIGNALING BY WNT | 318 | 3.02e-02 | -0.070700 | 2.71e-01 |
| REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES | 11 | 3.02e-02 | -0.377000 | 2.71e-01 |
| REACTOME PHOSPHORYLATION OF THE APC C | 20 | 3.06e-02 | -0.279000 | 2.71e-01 |
| REACTOME INTRAFLAGELLAR TRANSPORT | 50 | 3.08e-02 | -0.177000 | 2.71e-01 |
| REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT | 77 | 3.08e-02 | -0.142000 | 2.71e-01 |
| REACTOME OXIDATIVE STRESS INDUCED SENESCENCE | 118 | 3.11e-02 | -0.115000 | 2.71e-01 |
| REACTOME S PHASE | 159 | 3.12e-02 | -0.099000 | 2.71e-01 |
| REACTOME FORMATION OF LATERAL PLATE MESODERM | 5 | 3.12e-02 | -0.556000 | 2.71e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS | 11 | 3.12e-02 | -0.375000 | 2.71e-01 |
| REACTOME RHOU GTPASE CYCLE | 37 | 3.17e-02 | -0.204000 | 2.74e-01 |
| REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS | 6 | 3.19e-02 | 0.506000 | 2.74e-01 |
| REACTOME INITIAL TRIGGERING OF COMPLEMENT | 21 | 3.24e-02 | 0.270000 | 2.77e-01 |
| REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE | 11 | 3.25e-02 | 0.372000 | 2.77e-01 |
| REACTOME SIGNALING BY CSF3 G CSF | 30 | 3.31e-02 | 0.225000 | 2.80e-01 |
| REACTOME HS GAG DEGRADATION | 19 | 3.34e-02 | 0.282000 | 2.81e-01 |
| REACTOME CITRIC ACID CYCLE TCA CYCLE | 21 | 3.38e-02 | -0.268000 | 2.83e-01 |
| REACTOME NEGATIVE REGULATION OF FLT3 | 15 | 3.43e-02 | 0.316000 | 2.86e-01 |
| REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE | 81 | 3.48e-02 | -0.136000 | 2.89e-01 |
| REACTOME CD22 MEDIATED BCR REGULATION | 5 | 3.50e-02 | 0.544000 | 2.89e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | 21 | 3.53e-02 | -0.265000 | 2.90e-01 |
| REACTOME DNA REPLICATION PRE INITIATION | 150 | 3.59e-02 | -0.099200 | 2.90e-01 |
| REACTOME O LINKED GLYCOSYLATION | 109 | 3.59e-02 | 0.116000 | 2.90e-01 |
| REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | 24 | 3.60e-02 | 0.247000 | 2.90e-01 |
| REACTOME PECAM1 INTERACTIONS | 12 | 3.61e-02 | 0.349000 | 2.90e-01 |
| REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | 63 | 3.69e-02 | 0.152000 | 2.96e-01 |
| REACTOME NCAM1 INTERACTIONS | 41 | 3.72e-02 | 0.188000 | 2.97e-01 |
| REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE | 76 | 3.76e-02 | -0.138000 | 2.98e-01 |
| REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | 160 | 3.78e-02 | -0.095100 | 2.98e-01 |
| REACTOME EUKARYOTIC TRANSLATION ELONGATION | 87 | 3.79e-02 | 0.129000 | 2.98e-01 |
| REACTOME REGULATION OF INSULIN SECRETION | 77 | 3.82e-02 | 0.137000 | 2.98e-01 |
| REACTOME INWARDLY RECTIFYING K CHANNELS | 35 | 3.85e-02 | 0.202000 | 2.99e-01 |
| REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA | 14 | 3.96e-02 | -0.318000 | 3.06e-01 |
| REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR | 66 | 4.04e-02 | -0.146000 | 3.12e-01 |
| REACTOME HDMS DEMETHYLATE HISTONES | 40 | 4.10e-02 | -0.187000 | 3.13e-01 |
| REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES | 77 | 4.10e-02 | -0.135000 | 3.13e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | 36 | 4.14e-02 | -0.196000 | 3.13e-01 |
| REACTOME ANDROGEN BIOSYNTHESIS | 11 | 4.15e-02 | -0.355000 | 3.13e-01 |
| REACTOME REGULATION OF PTEN GENE TRANSCRIPTION | 59 | 4.16e-02 | -0.153000 | 3.13e-01 |
| REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | 52 | 4.17e-02 | -0.163000 | 3.13e-01 |
| REACTOME GPCR LIGAND BINDING | 444 | 4.25e-02 | 0.056200 | 3.17e-01 |
| REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE | 43 | 4.33e-02 | -0.178000 | 3.19e-01 |
| REACTOME ACTIVATION OF SMO | 18 | 4.35e-02 | -0.275000 | 3.19e-01 |
| REACTOME TRIGLYCERIDE CATABOLISM | 23 | 4.36e-02 | 0.243000 | 3.19e-01 |
| REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | 23 | 4.36e-02 | 0.243000 | 3.19e-01 |
| REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES | 30 | 4.37e-02 | 0.213000 | 3.19e-01 |
| REACTOME CA2 ACTIVATED K CHANNELS | 9 | 4.44e-02 | 0.387000 | 3.20e-01 |
| REACTOME RECYCLING PATHWAY OF L1 | 43 | 4.45e-02 | -0.177000 | 3.20e-01 |
| REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 62 | 4.45e-02 | 0.148000 | 3.20e-01 |
| REACTOME NEF MEDIATED CD8 DOWN REGULATION | 7 | 4.46e-02 | -0.438000 | 3.20e-01 |
| REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES | 18 | 4.48e-02 | 0.273000 | 3.20e-01 |
| REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM | 9 | 4.56e-02 | 0.385000 | 3.24e-01 |
| REACTOME POTASSIUM CHANNELS | 102 | 4.63e-02 | 0.114000 | 3.27e-01 |
| REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING | 32 | 4.68e-02 | -0.203000 | 3.27e-01 |
| REACTOME CHOLESTEROL BIOSYNTHESIS | 25 | 4.70e-02 | -0.229000 | 3.27e-01 |
| REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS | 6 | 4.71e-02 | 0.468000 | 3.27e-01 |
| REACTOME CELLULAR HEXOSE TRANSPORT | 21 | 4.72e-02 | 0.250000 | 3.27e-01 |
| REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING | 5 | 4.73e-02 | 0.512000 | 3.27e-01 |
| REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING | 11 | 4.75e-02 | 0.345000 | 3.28e-01 |
| REACTOME SIGNALING BY PDGF | 57 | 4.78e-02 | 0.152000 | 3.29e-01 |
| REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS | 46 | 4.84e-02 | -0.168000 | 3.31e-01 |
| REACTOME INTERLEUKIN 2 FAMILY SIGNALING | 40 | 4.92e-02 | 0.180000 | 3.35e-01 |
| REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION | 20 | 4.98e-02 | -0.253000 | 3.38e-01 |
| REACTOME RHOJ GTPASE CYCLE | 51 | 5.06e-02 | -0.158000 | 3.42e-01 |
| REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | 38 | 5.10e-02 | 0.183000 | 3.43e-01 |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 37 | 5.12e-02 | -0.185000 | 3.43e-01 |
| REACTOME METABOLISM OF AMINE DERIVED HORMONES | 17 | 5.13e-02 | 0.273000 | 3.43e-01 |
| REACTOME HIV LIFE CYCLE | 145 | 5.18e-02 | -0.093600 | 3.44e-01 |
| REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA | 52 | 5.21e-02 | 0.156000 | 3.44e-01 |
| REACTOME DNA REPLICATION | 178 | 5.21e-02 | -0.084400 | 3.44e-01 |
| REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION | 8 | 5.29e-02 | 0.395000 | 3.47e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS | 43 | 5.35e-02 | -0.170000 | 3.49e-01 |
| REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS | 10 | 5.39e-02 | 0.352000 | 3.49e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY | 156 | 5.42e-02 | -0.089300 | 3.49e-01 |
| REACTOME G1 S SPECIFIC TRANSCRIPTION | 28 | 5.42e-02 | -0.210000 | 3.49e-01 |
| REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | 296 | 5.43e-02 | -0.065000 | 3.49e-01 |
| REACTOME MITOCHONDRIAL BIOGENESIS | 87 | 5.44e-02 | -0.119000 | 3.49e-01 |
| REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC | 52 | 5.50e-02 | -0.154000 | 3.51e-01 |
| REACTOME DIGESTION | 17 | 5.52e-02 | 0.269000 | 3.52e-01 |
| REACTOME SEMAPHORIN INTERACTIONS | 61 | 5.58e-02 | 0.142000 | 3.53e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 | 117 | 5.60e-02 | -0.102000 | 3.53e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS | 52 | 5.65e-02 | -0.153000 | 3.55e-01 |
| REACTOME GENE SILENCING BY RNA | 133 | 5.82e-02 | -0.095100 | 3.65e-01 |
| REACTOME ERBB2 ACTIVATES PTK6 SIGNALING | 13 | 5.85e-02 | 0.303000 | 3.65e-01 |
| REACTOME SIGNAL AMPLIFICATION | 33 | 5.92e-02 | 0.190000 | 3.67e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION | 10 | 5.93e-02 | -0.344000 | 3.67e-01 |
| REACTOME DEADENYLATION DEPENDENT MRNA DECAY | 56 | 5.98e-02 | -0.145000 | 3.69e-01 |
| REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS | 16 | 6.00e-02 | -0.272000 | 3.69e-01 |
| REACTOME GLUCONEOGENESIS | 33 | 6.02e-02 | 0.189000 | 3.69e-01 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | 11 | 6.14e-02 | 0.326000 | 3.73e-01 |
| REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | 9 | 6.16e-02 | -0.360000 | 3.73e-01 |
| REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE | 71 | 6.16e-02 | -0.128000 | 3.73e-01 |
| REACTOME PRC2 METHYLATES HISTONES AND DNA | 65 | 6.19e-02 | -0.134000 | 3.73e-01 |
| REACTOME INTERLEUKIN 15 SIGNALING | 13 | 6.20e-02 | 0.299000 | 3.73e-01 |
| REACTOME ASPIRIN ADME | 42 | 6.23e-02 | 0.166000 | 3.73e-01 |
| REACTOME INACTIVATION OF CSF3 G CSF SIGNALING | 25 | 6.25e-02 | 0.215000 | 3.73e-01 |
| REACTOME MITOCHONDRIAL TRANSLATION | 93 | 6.38e-02 | -0.111000 | 3.80e-01 |
| REACTOME ATTACHMENT AND ENTRY | 16 | 6.42e-02 | 0.267000 | 3.80e-01 |
| REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS | 5 | 6.46e-02 | 0.477000 | 3.81e-01 |
| REACTOME ESTROGEN DEPENDENT GENE EXPRESSION | 140 | 6.48e-02 | -0.090400 | 3.81e-01 |
| REACTOME CONDENSATION OF PROPHASE CHROMOSOMES | 66 | 6.49e-02 | -0.131000 | 3.81e-01 |
| REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION | 8 | 6.56e-02 | 0.376000 | 3.81e-01 |
| REACTOME GABA B RECEPTOR ACTIVATION | 43 | 6.56e-02 | 0.162000 | 3.81e-01 |
| REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION | 10 | 6.56e-02 | 0.336000 | 3.81e-01 |
| REACTOME SIGNALING BY ERBB2 | 50 | 6.60e-02 | 0.150000 | 3.82e-01 |
| REACTOME METABOLISM OF STEROIDS | 150 | 6.63e-02 | -0.086900 | 3.82e-01 |
| REACTOME CRMPS IN SEMA3A SIGNALING | 15 | 6.68e-02 | 0.273000 | 3.82e-01 |
| REACTOME INTERLEUKIN 12 FAMILY SIGNALING | 53 | 6.69e-02 | 0.145000 | 3.82e-01 |
| REACTOME AQUAPORIN MEDIATED TRANSPORT | 51 | 6.72e-02 | 0.148000 | 3.82e-01 |
| REACTOME G0 AND EARLY G1 | 27 | 6.73e-02 | -0.203000 | 3.82e-01 |
| REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 | 12 | 6.75e-02 | 0.305000 | 3.82e-01 |
| REACTOME SYNAPTIC ADHESION LIKE MOLECULES | 19 | 6.82e-02 | 0.242000 | 3.83e-01 |
| REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | 23 | 6.85e-02 | 0.219000 | 3.83e-01 |
| REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY | 36 | 6.88e-02 | -0.175000 | 3.83e-01 |
| REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | 36 | 6.88e-02 | -0.175000 | 3.83e-01 |
| REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS | 9 | 6.88e-02 | 0.350000 | 3.83e-01 |
| REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL | 41 | 6.94e-02 | -0.164000 | 3.83e-01 |
| REACTOME PURINE CATABOLISM | 17 | 6.96e-02 | -0.254000 | 3.83e-01 |
| REACTOME AUTOPHAGY | 144 | 6.96e-02 | -0.087600 | 3.83e-01 |
| REACTOME HEME SIGNALING | 47 | 6.98e-02 | -0.153000 | 3.83e-01 |
| REACTOME PASSIVE TRANSPORT BY AQUAPORINS | 13 | 6.99e-02 | 0.290000 | 3.83e-01 |
| REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS | 37 | 7.02e-02 | -0.172000 | 3.83e-01 |
| REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | 91 | 7.07e-02 | 0.110000 | 3.85e-01 |
| REACTOME STAT5 ACTIVATION | 7 | 7.20e-02 | 0.393000 | 3.90e-01 |
| REACTOME APOPTOTIC EXECUTION PHASE | 49 | 7.35e-02 | -0.148000 | 3.95e-01 |
| REACTOME MULTIFUNCTIONAL ANION EXCHANGERS | 9 | 7.35e-02 | 0.344000 | 3.95e-01 |
| REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS | 41 | 7.37e-02 | -0.161000 | 3.95e-01 |
| REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | 101 | 7.38e-02 | 0.103000 | 3.95e-01 |
| REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | 49 | 7.48e-02 | -0.147000 | 3.99e-01 |
| REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | 8 | 7.50e-02 | -0.363000 | 3.99e-01 |
| REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY | 67 | 7.55e-02 | -0.126000 | 4.00e-01 |
| REACTOME CIRCADIAN CLOCK | 68 | 7.66e-02 | -0.124000 | 4.05e-01 |
| REACTOME GLUCAGON TYPE LIGAND RECEPTORS | 32 | 7.72e-02 | 0.180000 | 4.06e-01 |
| REACTOME GERM LAYER FORMATION AT GASTRULATION | 17 | 7.79e-02 | -0.247000 | 4.07e-01 |
| REACTOME SHC1 EVENTS IN ERBB2 SIGNALING | 22 | 7.81e-02 | 0.217000 | 4.07e-01 |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 688 | 7.84e-02 | 0.039400 | 4.07e-01 |
| REACTOME PROCESSING OF INTRONLESS PRE MRNAS | 19 | 7.84e-02 | -0.233000 | 4.07e-01 |
| REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | 20 | 7.91e-02 | -0.227000 | 4.10e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER | 28 | 7.99e-02 | -0.191000 | 4.12e-01 |
| REACTOME CREATINE METABOLISM | 9 | 8.02e-02 | 0.337000 | 4.12e-01 |
| REACTOME GAB1 SIGNALOSOME | 17 | 8.03e-02 | 0.245000 | 4.12e-01 |
| REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 100 | 8.07e-02 | -0.101000 | 4.13e-01 |
| REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING | 8 | 8.17e-02 | -0.355000 | 4.16e-01 |
| REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION | 8 | 8.26e-02 | -0.354000 | 4.20e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES | 16 | 8.30e-02 | -0.250000 | 4.21e-01 |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 8.34e-02 | -0.180000 | 4.22e-01 |
| REACTOME FLT3 SIGNALING | 38 | 8.41e-02 | 0.162000 | 4.24e-01 |
| REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES | 6 | 8.57e-02 | 0.405000 | 4.30e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS | 100 | 8.67e-02 | -0.099100 | 4.33e-01 |
| REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 | 9 | 8.69e-02 | 0.330000 | 4.33e-01 |
| REACTOME DEADENYLATION OF MRNA | 25 | 8.73e-02 | -0.198000 | 4.35e-01 |
| REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION | 26 | 8.91e-02 | -0.193000 | 4.40e-01 |
| REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | 35 | 8.93e-02 | -0.166000 | 4.40e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PI | 17 | 8.93e-02 | 0.238000 | 4.40e-01 |
| REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS | 7 | 8.96e-02 | -0.371000 | 4.40e-01 |
| REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS | 33 | 9.00e-02 | -0.171000 | 4.41e-01 |
| REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN | 37 | 9.10e-02 | -0.161000 | 4.44e-01 |
| REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | 9 | 9.13e-02 | 0.325000 | 4.44e-01 |
| REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS | 38 | 9.21e-02 | 0.158000 | 4.44e-01 |
| REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS | 6 | 9.21e-02 | -0.397000 | 4.44e-01 |
| REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | 93 | 9.21e-02 | 0.101000 | 4.44e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS | 5 | 9.21e-02 | -0.435000 | 4.44e-01 |
| REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION | 10 | 9.39e-02 | 0.306000 | 4.50e-01 |
| REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET | 8 | 9.40e-02 | 0.342000 | 4.50e-01 |
| REACTOME GASTRULATION | 49 | 9.53e-02 | -0.138000 | 4.54e-01 |
| REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | 13 | 9.56e-02 | -0.267000 | 4.54e-01 |
| REACTOME INTERLEUKIN 2 SIGNALING | 11 | 9.61e-02 | 0.290000 | 4.54e-01 |
| REACTOME MEIOSIS | 110 | 9.63e-02 | -0.091800 | 4.54e-01 |
| REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING | 24 | 9.64e-02 | 0.196000 | 4.54e-01 |
| REACTOME DNA DOUBLE STRAND BREAK RESPONSE | 74 | 9.66e-02 | -0.112000 | 4.54e-01 |
| REACTOME ERBB2 REGULATES CELL MOTILITY | 15 | 9.73e-02 | 0.247000 | 4.56e-01 |
| REACTOME ATORVASTATIN ADME | 9 | 9.74e-02 | 0.319000 | 4.56e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN | 21 | 9.80e-02 | -0.209000 | 4.56e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION | 41 | 9.82e-02 | -0.149000 | 4.56e-01 |
| REACTOME SPERM MOTILITY AND TAXES | 9 | 9.82e-02 | 0.318000 | 4.56e-01 |
| REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS | 28 | 1.00e-01 | -0.179000 | 4.63e-01 |
| REACTOME RND2 GTPASE CYCLE | 42 | 1.01e-01 | -0.146000 | 4.63e-01 |
| REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION | 361 | 1.01e-01 | -0.050300 | 4.63e-01 |
| REACTOME INTRA GOLGI TRAFFIC | 43 | 1.01e-01 | -0.145000 | 4.63e-01 |
| REACTOME REPRESSION OF WNT TARGET GENES | 14 | 1.02e-01 | -0.253000 | 4.65e-01 |
| REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS | 87 | 1.02e-01 | -0.101000 | 4.65e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS | 20 | 1.03e-01 | -0.211000 | 4.66e-01 |
| REACTOME G ALPHA Z SIGNALLING EVENTS | 48 | 1.03e-01 | 0.136000 | 4.66e-01 |
| REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS | 43 | 1.03e-01 | -0.144000 | 4.66e-01 |
| REACTOME NUCLEAR IMPORT OF REV PROTEIN | 34 | 1.06e-01 | -0.160000 | 4.77e-01 |
| REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 | 7 | 1.06e-01 | 0.352000 | 4.78e-01 |
| REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN | 6 | 1.07e-01 | 0.381000 | 4.78e-01 |
| REACTOME MAP2K AND MAPK ACTIVATION | 38 | 1.08e-01 | 0.151000 | 4.79e-01 |
| REACTOME KINESINS | 59 | 1.08e-01 | -0.121000 | 4.79e-01 |
| REACTOME PROTEIN UBIQUITINATION | 76 | 1.08e-01 | -0.107000 | 4.79e-01 |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 127 | 1.08e-01 | -0.082500 | 4.79e-01 |
| REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION | 62 | 1.08e-01 | -0.118000 | 4.79e-01 |
| REACTOME TERMINAL PATHWAY OF COMPLEMENT | 8 | 1.09e-01 | 0.328000 | 4.79e-01 |
| REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER | 15 | 1.09e-01 | 0.239000 | 4.79e-01 |
| REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | 15 | 1.09e-01 | -0.239000 | 4.80e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS | 121 | 1.10e-01 | -0.084200 | 4.81e-01 |
| REACTOME VISUAL PHOTOTRANSDUCTION | 93 | 1.10e-01 | 0.095800 | 4.82e-01 |
| REACTOME INTERLEUKIN 23 SIGNALING | 9 | 1.11e-01 | 0.307000 | 4.85e-01 |
| REACTOME DISEASES OF DNA REPAIR | 51 | 1.12e-01 | -0.129000 | 4.86e-01 |
| REACTOME PROGRAMMED CELL DEATH | 204 | 1.12e-01 | -0.064500 | 4.86e-01 |
| REACTOME ION CHANNEL TRANSPORT | 172 | 1.15e-01 | 0.069700 | 4.94e-01 |
| REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | 28 | 1.15e-01 | -0.172000 | 4.94e-01 |
| REACTOME PYROPTOSIS | 27 | 1.15e-01 | -0.175000 | 4.94e-01 |
| REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 | 12 | 1.15e-01 | 0.263000 | 4.94e-01 |
| REACTOME AMYLOID FIBER FORMATION | 102 | 1.15e-01 | 0.090200 | 4.94e-01 |
| REACTOME OTHER SEMAPHORIN INTERACTIONS | 18 | 1.16e-01 | 0.214000 | 4.94e-01 |
| REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | 20 | 1.17e-01 | -0.203000 | 4.94e-01 |
| REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS | 43 | 1.17e-01 | 0.138000 | 4.94e-01 |
| REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | 39 | 1.17e-01 | 0.145000 | 4.94e-01 |
| REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | 32 | 1.17e-01 | -0.160000 | 4.94e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 | 15 | 1.18e-01 | -0.233000 | 4.94e-01 |
| REACTOME SUMOYLATION OF SUMOYLATION PROTEINS | 35 | 1.19e-01 | -0.152000 | 4.94e-01 |
| REACTOME SIGNALING BY HEDGEHOG | 148 | 1.19e-01 | -0.074200 | 4.94e-01 |
| REACTOME FANCONI ANEMIA PATHWAY | 35 | 1.20e-01 | -0.152000 | 4.94e-01 |
| REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION | 98 | 1.20e-01 | -0.090900 | 4.94e-01 |
| REACTOME PLASMA LIPOPROTEIN REMODELING | 33 | 1.20e-01 | 0.156000 | 4.94e-01 |
| REACTOME DEFECTIVE GALNT3 CAUSES HFTC | 16 | 1.20e-01 | 0.224000 | 4.94e-01 |
| REACTOME LONG TERM POTENTIATION | 22 | 1.20e-01 | 0.191000 | 4.94e-01 |
| REACTOME CELLULAR RESPONSE TO HEAT STRESS | 99 | 1.21e-01 | -0.090300 | 4.94e-01 |
| REACTOME O LINKED GLYCOSYLATION OF MUCINS | 61 | 1.21e-01 | 0.115000 | 4.94e-01 |
| REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA | 37 | 1.21e-01 | -0.147000 | 4.94e-01 |
| REACTOME ACTIVATION OF RAC1 | 12 | 1.21e-01 | -0.259000 | 4.94e-01 |
| REACTOME UCH PROTEINASES | 99 | 1.22e-01 | -0.089900 | 4.97e-01 |
| REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 | 16 | 1.22e-01 | -0.223000 | 4.97e-01 |
| REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES | 77 | 1.22e-01 | 0.102000 | 4.97e-01 |
| REACTOME MATURATION OF PROTEIN 3A | 9 | 1.23e-01 | 0.297000 | 4.97e-01 |
| REACTOME STIMULI SENSING CHANNELS | 100 | 1.23e-01 | 0.089300 | 4.97e-01 |
| REACTOME REGULATION OF SIGNALING BY CBL | 22 | 1.24e-01 | 0.190000 | 4.97e-01 |
| REACTOME AMINO ACID CONJUGATION | 9 | 1.24e-01 | 0.296000 | 4.97e-01 |
| REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX | 83 | 1.24e-01 | -0.097500 | 5.00e-01 |
| REACTOME INTEGRATION OF ENERGY METABOLISM | 105 | 1.25e-01 | 0.086600 | 5.01e-01 |
| REACTOME GPER1 SIGNALING | 45 | 1.26e-01 | 0.132000 | 5.03e-01 |
| REACTOME NEPHRIN FAMILY INTERACTIONS | 22 | 1.26e-01 | -0.188000 | 5.04e-01 |
| REACTOME SYNTHESIS OF DNA | 119 | 1.27e-01 | -0.081000 | 5.05e-01 |
| REACTOME PD 1 SIGNALING | 21 | 1.27e-01 | 0.192000 | 5.06e-01 |
| REACTOME DIGESTION AND ABSORPTION | 22 | 1.28e-01 | 0.188000 | 5.06e-01 |
| REACTOME PI3K EVENTS IN ERBB2 SIGNALING | 16 | 1.29e-01 | 0.219000 | 5.09e-01 |
| REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION | 8 | 1.29e-01 | 0.310000 | 5.09e-01 |
| REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER | 18 | 1.31e-01 | 0.206000 | 5.14e-01 |
| REACTOME FATTY ACIDS | 15 | 1.31e-01 | 0.225000 | 5.14e-01 |
| REACTOME RESPONSE TO METAL IONS | 14 | 1.32e-01 | -0.233000 | 5.15e-01 |
| REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS | 17 | 1.32e-01 | 0.211000 | 5.16e-01 |
| REACTOME ENDOGENOUS STEROLS | 26 | 1.33e-01 | 0.170000 | 5.19e-01 |
| REACTOME MAPK6 MAPK4 SIGNALING | 91 | 1.34e-01 | -0.090800 | 5.20e-01 |
| REACTOME CGMP EFFECTS | 16 | 1.35e-01 | 0.216000 | 5.20e-01 |
| REACTOME DISINHIBITION OF SNARE FORMATION | 5 | 1.35e-01 | -0.386000 | 5.20e-01 |
| REACTOME DNA DAMAGE BYPASS | 47 | 1.35e-01 | -0.126000 | 5.21e-01 |
| REACTOME SNRNP ASSEMBLY | 53 | 1.37e-01 | -0.118000 | 5.25e-01 |
| REACTOME RNA POLYMERASE I PROMOTER ESCAPE | 83 | 1.37e-01 | -0.094500 | 5.25e-01 |
| REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | 67 | 1.38e-01 | -0.105000 | 5.28e-01 |
| REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY | 72 | 1.38e-01 | -0.101000 | 5.28e-01 |
| REACTOME REGULATION OF BACH1 ACTIVITY | 11 | 1.40e-01 | 0.257000 | 5.29e-01 |
| REACTOME INDUCTION OF CELL CELL FUSION | 12 | 1.40e-01 | 0.246000 | 5.29e-01 |
| REACTOME BIOTIN TRANSPORT AND METABOLISM | 10 | 1.40e-01 | -0.269000 | 5.29e-01 |
| REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING | 6 | 1.40e-01 | 0.348000 | 5.29e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PS | 22 | 1.40e-01 | 0.182000 | 5.29e-01 |
| REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT | 5 | 1.41e-01 | -0.381000 | 5.29e-01 |
| REACTOME TIGHT JUNCTION INTERACTIONS | 29 | 1.41e-01 | 0.158000 | 5.29e-01 |
| REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION | 9 | 1.41e-01 | -0.283000 | 5.29e-01 |
| REACTOME LAMININ INTERACTIONS | 28 | 1.41e-01 | 0.161000 | 5.29e-01 |
| REACTOME G ALPHA S SIGNALLING EVENTS | 155 | 1.42e-01 | 0.068300 | 5.30e-01 |
| REACTOME EUKARYOTIC TRANSLATION INITIATION | 110 | 1.43e-01 | 0.080900 | 5.30e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER | 77 | 1.43e-01 | 0.096600 | 5.30e-01 |
| REACTOME RIBAVIRIN ADME | 11 | 1.45e-01 | -0.254000 | 5.34e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 | 60 | 1.45e-01 | -0.109000 | 5.34e-01 |
| REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES | 33 | 1.45e-01 | 0.146000 | 5.34e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION | 102 | 1.45e-01 | -0.083400 | 5.34e-01 |
| REACTOME RHOG GTPASE CYCLE | 71 | 1.46e-01 | -0.099800 | 5.34e-01 |
| REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS | 5 | 1.46e-01 | 0.375000 | 5.34e-01 |
| REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | 16 | 1.46e-01 | 0.210000 | 5.34e-01 |
| REACTOME GLUTAMATE AND GLUTAMINE METABOLISM | 13 | 1.47e-01 | -0.232000 | 5.35e-01 |
| REACTOME RND3 GTPASE CYCLE | 41 | 1.47e-01 | -0.131000 | 5.36e-01 |
| REACTOME PEPTIDE HORMONE BIOSYNTHESIS | 13 | 1.48e-01 | -0.232000 | 5.36e-01 |
| REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | 73 | 1.48e-01 | -0.097800 | 5.38e-01 |
| REACTOME HYDROLYSIS OF LPC | 9 | 1.49e-01 | 0.278000 | 5.38e-01 |
| REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | 31 | 1.49e-01 | -0.150000 | 5.39e-01 |
| REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION | 5 | 1.50e-01 | -0.372000 | 5.39e-01 |
| REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS | 21 | 1.50e-01 | 0.181000 | 5.39e-01 |
| REACTOME PRE NOTCH EXPRESSION AND PROCESSING | 112 | 1.51e-01 | -0.078500 | 5.41e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES | 49 | 1.52e-01 | -0.118000 | 5.41e-01 |
| REACTOME VIRAL MESSENGER RNA SYNTHESIS | 44 | 1.52e-01 | -0.125000 | 5.41e-01 |
| REACTOME NEDDYLATION | 235 | 1.52e-01 | -0.054200 | 5.41e-01 |
| REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | 16 | 1.52e-01 | -0.207000 | 5.41e-01 |
| REACTOME PTK6 REGULATES CELL CYCLE | 6 | 1.53e-01 | 0.337000 | 5.43e-01 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | 111 | 1.54e-01 | -0.078300 | 5.44e-01 |
| REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS | 10 | 1.55e-01 | -0.260000 | 5.44e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA | 27 | 1.55e-01 | -0.158000 | 5.44e-01 |
| REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS | 16 | 1.55e-01 | 0.205000 | 5.44e-01 |
| REACTOME TCR SIGNALING | 113 | 1.56e-01 | -0.077300 | 5.45e-01 |
| REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | 13 | 1.56e-01 | 0.227000 | 5.45e-01 |
| REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA | 5 | 1.56e-01 | -0.366000 | 5.45e-01 |
| REACTOME REGULATION OF PTEN MRNA TRANSLATION | 9 | 1.57e-01 | -0.272000 | 5.49e-01 |
| REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE | 5 | 1.59e-01 | 0.364000 | 5.52e-01 |
| REACTOME LGI ADAM INTERACTIONS | 14 | 1.60e-01 | 0.217000 | 5.52e-01 |
| REACTOME HEDGEHOG ON STATE | 85 | 1.60e-01 | -0.088200 | 5.52e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS | 83 | 1.60e-01 | -0.089200 | 5.52e-01 |
| REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION | 19 | 1.60e-01 | 0.186000 | 5.52e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS | 19 | 1.60e-01 | 0.186000 | 5.52e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | 25 | 1.61e-01 | 0.162000 | 5.52e-01 |
| REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY | 5 | 1.62e-01 | 0.362000 | 5.52e-01 |
| REACTOME CALCITONIN LIKE LIGAND RECEPTORS | 10 | 1.62e-01 | 0.256000 | 5.52e-01 |
| REACTOME NONSENSE MEDIATED DECAY NMD | 107 | 1.62e-01 | 0.078300 | 5.52e-01 |
| REACTOME BICARBONATE TRANSPORTERS | 10 | 1.62e-01 | 0.255000 | 5.53e-01 |
| REACTOME INTEGRATION OF PROVIRUS | 9 | 1.63e-01 | -0.269000 | 5.53e-01 |
| REACTOME CHYLOMICRON CLEARANCE | 5 | 1.63e-01 | -0.360000 | 5.53e-01 |
| REACTOME PROTEIN REPAIR | 6 | 1.64e-01 | -0.328000 | 5.55e-01 |
| REACTOME SIGNALING BY ERBB4 | 57 | 1.65e-01 | 0.106000 | 5.56e-01 |
| REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS | 41 | 1.65e-01 | -0.125000 | 5.56e-01 |
| REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION | 84 | 1.67e-01 | -0.087300 | 5.58e-01 |
| REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS | 42 | 1.67e-01 | 0.123000 | 5.58e-01 |
| REACTOME PREDNISONE ADME | 10 | 1.67e-01 | 0.252000 | 5.58e-01 |
| REACTOME SYNDECAN INTERACTIONS | 26 | 1.67e-01 | 0.156000 | 5.58e-01 |
| REACTOME INTERLEUKIN 27 SIGNALING | 11 | 1.67e-01 | 0.240000 | 5.58e-01 |
| REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS | 16 | 1.68e-01 | 0.199000 | 5.60e-01 |
| REACTOME DOPAMINE RECEPTORS | 5 | 1.68e-01 | -0.356000 | 5.60e-01 |
| REACTOME COHESIN LOADING ONTO CHROMATIN | 8 | 1.69e-01 | -0.281000 | 5.61e-01 |
| REACTOME HEDGEHOG OFF STATE | 111 | 1.70e-01 | -0.075400 | 5.62e-01 |
| REACTOME CRISTAE FORMATION | 27 | 1.71e-01 | -0.152000 | 5.62e-01 |
| REACTOME PEPTIDE LIGAND BINDING RECEPTORS | 188 | 1.73e-01 | 0.057700 | 5.62e-01 |
| REACTOME SIGNALING BY MRAS COMPLEX MUTANTS | 7 | 1.73e-01 | -0.298000 | 5.62e-01 |
| REACTOME SIGNALING BY EGFR IN CANCER | 25 | 1.73e-01 | 0.158000 | 5.62e-01 |
| REACTOME SIGNALING BY ERBB2 IN CANCER | 26 | 1.73e-01 | 0.154000 | 5.62e-01 |
| REACTOME METALLOTHIONEINS BIND METALS | 11 | 1.73e-01 | -0.237000 | 5.62e-01 |
| REACTOME SURFACTANT METABOLISM | 28 | 1.73e-01 | 0.149000 | 5.62e-01 |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 250 | 1.74e-01 | 0.050000 | 5.62e-01 |
| REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | 111 | 1.74e-01 | 0.074700 | 5.62e-01 |
| REACTOME PEROXISOMAL LIPID METABOLISM | 28 | 1.74e-01 | -0.148000 | 5.62e-01 |
| REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 | 19 | 1.74e-01 | 0.180000 | 5.62e-01 |
| REACTOME METABOLISM OF LIPIDS | 709 | 1.74e-01 | -0.030000 | 5.62e-01 |
| REACTOME INTERLEUKIN 7 SIGNALING | 31 | 1.75e-01 | -0.141000 | 5.62e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS | 5 | 1.75e-01 | 0.350000 | 5.62e-01 |
| REACTOME NEF MEDIATED CD4 DOWN REGULATION | 9 | 1.75e-01 | -0.261000 | 5.62e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS | 14 | 1.77e-01 | -0.209000 | 5.65e-01 |
| REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | 22 | 1.77e-01 | -0.166000 | 5.65e-01 |
| REACTOME DISEASES OF GLYCOSYLATION | 137 | 1.77e-01 | 0.066800 | 5.65e-01 |
| REACTOME TRIGLYCERIDE METABOLISM | 35 | 1.78e-01 | 0.132000 | 5.66e-01 |
| REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS | 42 | 1.79e-01 | 0.120000 | 5.69e-01 |
| REACTOME MEIOTIC SYNAPSIS | 73 | 1.80e-01 | -0.090800 | 5.70e-01 |
| REACTOME CHROMOSOME MAINTENANCE | 130 | 1.81e-01 | -0.068000 | 5.72e-01 |
| REACTOME ETHANOL OXIDATION | 12 | 1.81e-01 | 0.223000 | 5.72e-01 |
| REACTOME RHOBTB2 GTPASE CYCLE | 22 | 1.83e-01 | -0.164000 | 5.77e-01 |
| REACTOME MITOCHONDRIAL UNCOUPLING | 5 | 1.85e-01 | -0.343000 | 5.82e-01 |
| REACTOME CYP2E1 REACTIONS | 10 | 1.85e-01 | 0.242000 | 5.83e-01 |
| REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION | 62 | 1.86e-01 | -0.097000 | 5.85e-01 |
| REACTOME ZINC TRANSPORTERS | 15 | 1.87e-01 | 0.197000 | 5.86e-01 |
| REACTOME DIGESTION OF DIETARY LIPID | 7 | 1.87e-01 | 0.288000 | 5.86e-01 |
| REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS | 30 | 1.88e-01 | 0.139000 | 5.87e-01 |
| REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE | 39 | 1.88e-01 | -0.122000 | 5.87e-01 |
| REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING | 38 | 1.89e-01 | 0.123000 | 5.88e-01 |
| REACTOME FORMATION OF PARAXIAL MESODERM | 22 | 1.90e-01 | -0.162000 | 5.89e-01 |
| REACTOME CELL CELL JUNCTION ORGANIZATION | 64 | 1.91e-01 | 0.094500 | 5.91e-01 |
| REACTOME SMOOTH MUSCLE CONTRACTION | 43 | 1.91e-01 | 0.115000 | 5.91e-01 |
| REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR | 11 | 1.91e-01 | -0.227000 | 5.91e-01 |
| REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | 15 | 1.93e-01 | -0.194000 | 5.94e-01 |
| REACTOME LIGAND RECEPTOR INTERACTIONS | 8 | 1.94e-01 | -0.265000 | 5.95e-01 |
| REACTOME DISEASES OF MITOTIC CELL CYCLE | 37 | 1.94e-01 | -0.123000 | 5.95e-01 |
| REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | 19 | 1.94e-01 | 0.172000 | 5.95e-01 |
| REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 17 | 1.95e-01 | 0.182000 | 5.95e-01 |
| REACTOME P75NTR REGULATES AXONOGENESIS | 9 | 1.95e-01 | 0.249000 | 5.95e-01 |
| REACTOME NEURONAL SYSTEM | 388 | 1.96e-01 | 0.038200 | 5.95e-01 |
| REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 66 | 1.96e-01 | -0.092000 | 5.95e-01 |
| REACTOME COBALAMIN CBL METABOLISM | 7 | 1.97e-01 | -0.282000 | 5.95e-01 |
| REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION | 5 | 1.97e-01 | 0.333000 | 5.95e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES | 12 | 1.98e-01 | -0.215000 | 5.98e-01 |
| REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 | 6 | 1.98e-01 | -0.303000 | 5.98e-01 |
| REACTOME NERVOUS SYSTEM DEVELOPMENT | 552 | 1.99e-01 | 0.032000 | 5.98e-01 |
| REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY | 16 | 1.99e-01 | 0.186000 | 5.98e-01 |
| REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS | 77 | 2.00e-01 | -0.084600 | 5.99e-01 |
| REACTOME SENSORY PERCEPTION OF SALTY TASTE | 6 | 2.00e-01 | 0.302000 | 5.99e-01 |
| REACTOME NUCLEAR SIGNALING BY ERBB4 | 32 | 2.01e-01 | 0.131000 | 6.00e-01 |
| REACTOME SIGNALING BY SCF KIT | 42 | 2.02e-01 | 0.114000 | 6.02e-01 |
| REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS | 58 | 2.02e-01 | -0.096900 | 6.02e-01 |
| REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 2.03e-01 | 0.130000 | 6.04e-01 |
| REACTOME ACYL CHAIN REMODELING OF DAG AND TAG | 5 | 2.04e-01 | 0.328000 | 6.05e-01 |
| REACTOME DNA METHYLATION | 58 | 2.04e-01 | -0.096400 | 6.05e-01 |
| REACTOME SIGNALING BY NOTCH2 | 32 | 2.05e-01 | 0.130000 | 6.05e-01 |
| REACTOME EGFR TRANSACTIVATION BY GASTRIN | 9 | 2.05e-01 | 0.244000 | 6.05e-01 |
| REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA | 5 | 2.06e-01 | -0.327000 | 6.06e-01 |
| REACTOME TRANSPORT OF FATTY ACIDS | 8 | 2.06e-01 | 0.258000 | 6.06e-01 |
| REACTOME INTERLEUKIN 18 SIGNALING | 8 | 2.07e-01 | -0.258000 | 6.07e-01 |
| REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 | 5 | 2.08e-01 | -0.325000 | 6.09e-01 |
| REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS | 28 | 2.08e-01 | 0.137000 | 6.09e-01 |
| REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | 14 | 2.10e-01 | -0.194000 | 6.13e-01 |
| REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | 14 | 2.10e-01 | 0.193000 | 6.13e-01 |
| REACTOME RECYCLING OF BILE ACIDS AND SALTS | 18 | 2.12e-01 | 0.170000 | 6.17e-01 |
| REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | 10 | 2.13e-01 | 0.227000 | 6.18e-01 |
| REACTOME JOSEPHIN DOMAIN DUBS | 11 | 2.14e-01 | 0.216000 | 6.18e-01 |
| REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA | 36 | 2.14e-01 | -0.120000 | 6.18e-01 |
| REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS | 9 | 2.14e-01 | -0.239000 | 6.18e-01 |
| REACTOME G PROTEIN MEDIATED EVENTS | 53 | 2.14e-01 | 0.098600 | 6.18e-01 |
| REACTOME G PROTEIN BETA GAMMA SIGNALLING | 30 | 2.15e-01 | 0.131000 | 6.18e-01 |
| REACTOME DOWNREGULATION OF ERBB2 SIGNALING | 29 | 2.15e-01 | 0.133000 | 6.18e-01 |
| REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING | 29 | 2.16e-01 | 0.133000 | 6.20e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES | 61 | 2.17e-01 | -0.091500 | 6.20e-01 |
| REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | 7 | 2.17e-01 | 0.269000 | 6.20e-01 |
| REACTOME NETRIN MEDIATED REPULSION SIGNALS | 8 | 2.17e-01 | 0.252000 | 6.20e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN | 13 | 2.18e-01 | 0.197000 | 6.20e-01 |
| REACTOME MET RECEPTOR ACTIVATION | 6 | 2.18e-01 | 0.290000 | 6.20e-01 |
| REACTOME KETONE BODY METABOLISM | 9 | 2.18e-01 | -0.237000 | 6.20e-01 |
| REACTOME CA DEPENDENT EVENTS | 36 | 2.19e-01 | 0.118000 | 6.22e-01 |
| REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 | 7 | 2.20e-01 | -0.268000 | 6.23e-01 |
| REACTOME CELLULAR RESPONSE TO HYPOXIA | 74 | 2.21e-01 | -0.082300 | 6.24e-01 |
| REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE | 25 | 2.21e-01 | -0.141000 | 6.24e-01 |
| REACTOME 2 LTR CIRCLE FORMATION | 7 | 2.22e-01 | -0.267000 | 6.24e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION | 12 | 2.22e-01 | -0.203000 | 6.24e-01 |
| REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE | 91 | 2.23e-01 | -0.074000 | 6.24e-01 |
| REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM | 6 | 2.23e-01 | 0.287000 | 6.24e-01 |
| REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | 105 | 2.24e-01 | 0.068700 | 6.26e-01 |
| REACTOME RESOLUTION OF D LOOP STRUCTURES | 33 | 2.25e-01 | -0.122000 | 6.27e-01 |
| REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS | 63 | 2.25e-01 | 0.088400 | 6.27e-01 |
| REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM | 7 | 2.25e-01 | 0.265000 | 6.28e-01 |
| REACTOME DECTIN 2 FAMILY | 26 | 2.26e-01 | 0.137000 | 6.28e-01 |
| REACTOME METAL ION SLC TRANSPORTERS | 23 | 2.26e-01 | 0.146000 | 6.28e-01 |
| REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS | 24 | 2.28e-01 | -0.142000 | 6.29e-01 |
| REACTOME ALPHA OXIDATION OF PHYTANATE | 6 | 2.28e-01 | -0.284000 | 6.29e-01 |
| REACTOME ESR MEDIATED SIGNALING | 210 | 2.28e-01 | -0.048300 | 6.29e-01 |
| REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA | 9 | 2.28e-01 | 0.232000 | 6.29e-01 |
| REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | 21 | 2.29e-01 | -0.152000 | 6.30e-01 |
| REACTOME TP53 REGULATES METABOLIC GENES | 81 | 2.29e-01 | -0.077300 | 6.30e-01 |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 2.31e-01 | 0.209000 | 6.32e-01 |
| REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION | 6 | 2.31e-01 | -0.282000 | 6.32e-01 |
| REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | 30 | 2.32e-01 | 0.126000 | 6.34e-01 |
| REACTOME BUDDING AND MATURATION OF HIV VIRION | 28 | 2.32e-01 | -0.130000 | 6.34e-01 |
| REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 16 | 2.34e-01 | 0.172000 | 6.35e-01 |
| REACTOME HISTIDINE CATABOLISM | 8 | 2.34e-01 | 0.243000 | 6.35e-01 |
| REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION | 5 | 2.34e-01 | -0.307000 | 6.35e-01 |
| REACTOME DEFECTS IN BIOTIN BTN METABOLISM | 8 | 2.35e-01 | -0.242000 | 6.37e-01 |
| REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS | 39 | 2.35e-01 | -0.110000 | 6.37e-01 |
| REACTOME SELECTIVE AUTOPHAGY | 79 | 2.37e-01 | -0.077000 | 6.38e-01 |
| REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM | 12 | 2.38e-01 | -0.197000 | 6.38e-01 |
| REACTOME PENTOSE PHOSPHATE PATHWAY | 12 | 2.38e-01 | -0.197000 | 6.38e-01 |
| REACTOME NGF INDEPENDANT TRKA ACTIVATION | 5 | 2.38e-01 | -0.305000 | 6.38e-01 |
| REACTOME MET ACTIVATES RAP1 AND RAC1 | 11 | 2.38e-01 | 0.205000 | 6.38e-01 |
| REACTOME RHOBTB GTPASE CYCLE | 34 | 2.39e-01 | -0.117000 | 6.39e-01 |
| REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX | 36 | 2.39e-01 | -0.113000 | 6.40e-01 |
| REACTOME G2 M DNA REPLICATION CHECKPOINT | 5 | 2.41e-01 | -0.303000 | 6.42e-01 |
| REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES | 507 | 2.41e-01 | 0.030400 | 6.43e-01 |
| REACTOME TRNA MODIFICATION IN THE MITOCHONDRION | 8 | 2.43e-01 | -0.238000 | 6.45e-01 |
| REACTOME GABA RECEPTOR ACTIVATION | 57 | 2.43e-01 | 0.089300 | 6.45e-01 |
| REACTOME DISEASES OF METABOLISM | 237 | 2.44e-01 | 0.044000 | 6.45e-01 |
| REACTOME PLATELET CALCIUM HOMEOSTASIS | 27 | 2.44e-01 | -0.130000 | 6.45e-01 |
| REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY | 10 | 2.44e-01 | -0.213000 | 6.46e-01 |
| REACTOME INTERLEUKIN 21 SIGNALING | 9 | 2.46e-01 | 0.224000 | 6.48e-01 |
| REACTOME G ALPHA 12 13 SIGNALLING EVENTS | 74 | 2.48e-01 | 0.077700 | 6.52e-01 |
| REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS | 6 | 2.48e-01 | 0.272000 | 6.52e-01 |
| REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 | 22 | 2.49e-01 | 0.142000 | 6.52e-01 |
| REACTOME PROSTANOID LIGAND RECEPTORS | 9 | 2.49e-01 | -0.222000 | 6.52e-01 |
| REACTOME AGGREPHAGY | 42 | 2.50e-01 | -0.103000 | 6.52e-01 |
| REACTOME METHIONINE SALVAGE PATHWAY | 6 | 2.50e-01 | -0.271000 | 6.52e-01 |
| REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS | 14 | 2.50e-01 | -0.177000 | 6.52e-01 |
| REACTOME FC EPSILON RECEPTOR FCERI SIGNALING | 127 | 2.51e-01 | -0.059000 | 6.52e-01 |
| REACTOME NEUREXINS AND NEUROLIGINS | 51 | 2.51e-01 | 0.092900 | 6.52e-01 |
| REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION | 11 | 2.51e-01 | -0.200000 | 6.52e-01 |
| REACTOME APOPTOSIS | 173 | 2.51e-01 | -0.050500 | 6.52e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | 28 | 2.52e-01 | -0.125000 | 6.52e-01 |
| REACTOME METABOLISM OF PORPHYRINS | 26 | 2.53e-01 | 0.130000 | 6.53e-01 |
| REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM | 6 | 2.54e-01 | -0.269000 | 6.53e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM | 38 | 2.54e-01 | 0.107000 | 6.53e-01 |
| REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS | 20 | 2.54e-01 | -0.147000 | 6.53e-01 |
| REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM | 21 | 2.54e-01 | -0.144000 | 6.53e-01 |
| REACTOME MET ACTIVATES PTPN11 | 5 | 2.55e-01 | 0.294000 | 6.53e-01 |
| REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING | 6 | 2.56e-01 | 0.268000 | 6.53e-01 |
| REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | 15 | 2.56e-01 | -0.169000 | 6.53e-01 |
| REACTOME IKBA VARIANT LEADS TO EDA ID | 6 | 2.57e-01 | -0.267000 | 6.53e-01 |
| REACTOME SIGNALING BY MAPK MUTANTS | 6 | 2.57e-01 | -0.267000 | 6.53e-01 |
| REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA | 5 | 2.57e-01 | -0.293000 | 6.53e-01 |
| REACTOME PLATELET SENSITIZATION BY LDL | 17 | 2.57e-01 | 0.159000 | 6.53e-01 |
| REACTOME MRNA SPLICING MINOR PATHWAY | 49 | 2.58e-01 | -0.093500 | 6.54e-01 |
| REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA | 6 | 2.60e-01 | -0.266000 | 6.58e-01 |
| REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION | 32 | 2.60e-01 | 0.115000 | 6.58e-01 |
| REACTOME PARACETAMOL ADME | 26 | 2.61e-01 | 0.127000 | 6.58e-01 |
| REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 | 16 | 2.61e-01 | -0.162000 | 6.58e-01 |
| REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY | 94 | 2.62e-01 | 0.066900 | 6.59e-01 |
| REACTOME STRIATED MUSCLE CONTRACTION | 35 | 2.62e-01 | 0.110000 | 6.59e-01 |
| REACTOME SIGNALING BY NUCLEAR RECEPTORS | 283 | 2.63e-01 | -0.038700 | 6.59e-01 |
| REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | 7 | 2.64e-01 | 0.244000 | 6.62e-01 |
| REACTOME AMINO ACIDS REGULATE MTORC1 | 53 | 2.65e-01 | -0.088500 | 6.63e-01 |
| REACTOME LIPOPHAGY | 9 | 2.66e-01 | 0.214000 | 6.64e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | 48 | 2.66e-01 | -0.092800 | 6.64e-01 |
| REACTOME ANCHORING FIBRIL FORMATION | 13 | 2.66e-01 | 0.178000 | 6.64e-01 |
| REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS | 16 | 2.67e-01 | 0.160000 | 6.64e-01 |
| REACTOME BETA OXIDATION OF PRISTANOYL COA | 9 | 2.68e-01 | -0.213000 | 6.65e-01 |
| REACTOME PTK6 PROMOTES HIF1A STABILIZATION | 6 | 2.68e-01 | 0.261000 | 6.66e-01 |
| REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | 14 | 2.69e-01 | 0.170000 | 6.67e-01 |
| REACTOME MEIOTIC RECOMBINATION | 80 | 2.70e-01 | -0.071400 | 6.67e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PC | 27 | 2.70e-01 | 0.123000 | 6.67e-01 |
| REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES | 7 | 2.71e-01 | -0.240000 | 6.68e-01 |
| REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS | 87 | 2.72e-01 | -0.068200 | 6.68e-01 |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 2.72e-01 | 0.138000 | 6.68e-01 |
| REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE | 5 | 2.73e-01 | -0.283000 | 6.69e-01 |
| REACTOME REGULATION OF NPAS4 MRNA TRANSLATION | 9 | 2.73e-01 | -0.211000 | 6.69e-01 |
| REACTOME ARACHIDONIC ACID METABOLISM | 57 | 2.73e-01 | 0.083900 | 6.69e-01 |
| REACTOME VXPX CARGO TARGETING TO CILIUM | 20 | 2.74e-01 | -0.141000 | 6.69e-01 |
| REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | 38 | 2.74e-01 | -0.103000 | 6.69e-01 |
| REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE | 49 | 2.74e-01 | -0.090200 | 6.69e-01 |
| REACTOME MITOTIC TELOPHASE CYTOKINESIS | 11 | 2.77e-01 | -0.189000 | 6.72e-01 |
| REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B | 24 | 2.78e-01 | -0.128000 | 6.72e-01 |
| REACTOME COMPLEX I BIOGENESIS | 49 | 2.78e-01 | -0.089500 | 6.72e-01 |
| REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS | 17 | 2.79e-01 | -0.152000 | 6.72e-01 |
| REACTOME INTERFERON ALPHA BETA SIGNALING | 70 | 2.79e-01 | 0.074800 | 6.72e-01 |
| REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS | 7 | 2.79e-01 | -0.236000 | 6.72e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION | 45 | 2.79e-01 | -0.093200 | 6.72e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | 14 | 2.79e-01 | -0.167000 | 6.72e-01 |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 64 | 2.80e-01 | 0.078100 | 6.72e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE | 5 | 2.80e-01 | -0.279000 | 6.72e-01 |
| REACTOME FLT3 SIGNALING BY CBL MUTANTS | 7 | 2.82e-01 | 0.235000 | 6.76e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION | 65 | 2.83e-01 | -0.077100 | 6.76e-01 |
| REACTOME METABOLISM OF FAT SOLUBLE VITAMINS | 46 | 2.83e-01 | 0.091500 | 6.76e-01 |
| REACTOME INTERLEUKIN 12 SIGNALING | 43 | 2.84e-01 | 0.094500 | 6.77e-01 |
| REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP | 104 | 2.86e-01 | -0.060600 | 6.80e-01 |
| REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA | 11 | 2.86e-01 | 0.186000 | 6.80e-01 |
| REACTOME EICOSANOIDS | 12 | 2.87e-01 | 0.177000 | 6.83e-01 |
| REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION | 42 | 2.88e-01 | 0.094700 | 6.84e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING | 5 | 2.89e-01 | 0.274000 | 6.84e-01 |
| REACTOME INTERLEUKIN 35 SIGNALLING | 12 | 2.89e-01 | 0.177000 | 6.84e-01 |
| REACTOME GAP JUNCTION ASSEMBLY | 36 | 2.90e-01 | -0.102000 | 6.84e-01 |
| REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION | 23 | 2.90e-01 | 0.127000 | 6.85e-01 |
| REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS | 32 | 2.91e-01 | -0.108000 | 6.85e-01 |
| REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS | 15 | 2.91e-01 | -0.157000 | 6.85e-01 |
| REACTOME NOD1 2 SIGNALING PATHWAY | 33 | 2.93e-01 | -0.106000 | 6.88e-01 |
| REACTOME HDL REMODELING | 10 | 2.95e-01 | 0.191000 | 6.92e-01 |
| REACTOME HDL ASSEMBLY | 8 | 2.96e-01 | -0.213000 | 6.93e-01 |
| REACTOME SIGNALING BY TGFB FAMILY MEMBERS | 119 | 2.96e-01 | -0.055400 | 6.93e-01 |
| REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY | 25 | 2.98e-01 | -0.120000 | 6.95e-01 |
| REACTOME FATTY ACID METABOLISM | 170 | 2.98e-01 | -0.046300 | 6.95e-01 |
| REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING | 74 | 2.98e-01 | 0.069900 | 6.95e-01 |
| REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION | 74 | 2.99e-01 | 0.069800 | 6.95e-01 |
| REACTOME ONCOGENE INDUCED SENESCENCE | 35 | 3.01e-01 | -0.101000 | 6.99e-01 |
| REACTOME PARASITE INFECTION | 57 | 3.02e-01 | 0.079100 | 6.99e-01 |
| REACTOME PLATELET HOMEOSTASIS | 85 | 3.04e-01 | 0.064500 | 7.03e-01 |
| REACTOME NUCLEOTIDE EXCISION REPAIR | 107 | 3.05e-01 | -0.057500 | 7.03e-01 |
| REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | 22 | 3.05e-01 | 0.126000 | 7.03e-01 |
| REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION | 6 | 3.06e-01 | 0.242000 | 7.03e-01 |
| REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING | 9 | 3.06e-01 | -0.197000 | 7.03e-01 |
| REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING | 46 | 3.07e-01 | -0.087000 | 7.03e-01 |
| REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS | 5 | 3.08e-01 | -0.264000 | 7.03e-01 |
| REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION | 11 | 3.08e-01 | -0.178000 | 7.03e-01 |
| REACTOME RESPIRATORY ELECTRON TRANSPORT | 90 | 3.08e-01 | -0.062200 | 7.03e-01 |
| REACTOME SARS COV 2 MODULATES AUTOPHAGY | 11 | 3.08e-01 | -0.178000 | 7.03e-01 |
| REACTOME PI3K EVENTS IN ERBB4 SIGNALING | 10 | 3.08e-01 | 0.186000 | 7.03e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII | 15 | 3.08e-01 | 0.152000 | 7.03e-01 |
| REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | 14 | 3.09e-01 | -0.157000 | 7.03e-01 |
| REACTOME ASSEMBLY OF THE HIV VIRION | 16 | 3.10e-01 | 0.147000 | 7.03e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL | 15 | 3.10e-01 | 0.151000 | 7.03e-01 |
| REACTOME AMINE LIGAND BINDING RECEPTORS | 40 | 3.10e-01 | -0.092800 | 7.03e-01 |
| REACTOME COPII MEDIATED VESICLE TRANSPORT | 66 | 3.10e-01 | -0.072200 | 7.03e-01 |
| REACTOME FGFR2 ALTERNATIVE SPLICING | 27 | 3.11e-01 | -0.113000 | 7.03e-01 |
| REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE | 35 | 3.11e-01 | -0.098900 | 7.03e-01 |
| REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION | 60 | 3.12e-01 | -0.075500 | 7.03e-01 |
| REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES | 34 | 3.12e-01 | 0.100000 | 7.03e-01 |
| REACTOME FGFR1B LIGAND BINDING AND ACTIVATION | 6 | 3.14e-01 | 0.238000 | 7.05e-01 |
| REACTOME MAPK3 ERK1 ACTIVATION | 10 | 3.14e-01 | -0.184000 | 7.06e-01 |
| REACTOME ACTIVATION OF TRKA RECEPTORS | 6 | 3.16e-01 | -0.236000 | 7.10e-01 |
| REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE | 6 | 3.17e-01 | -0.236000 | 7.10e-01 |
| REACTOME NEUTROPHIL DEGRANULATION | 460 | 3.18e-01 | 0.027200 | 7.11e-01 |
| REACTOME DISEASES OF IMMUNE SYSTEM | 29 | 3.19e-01 | 0.107000 | 7.12e-01 |
| REACTOME FORMATION OF AXIAL MESODERM | 14 | 3.20e-01 | -0.154000 | 7.14e-01 |
| REACTOME SODIUM CALCIUM EXCHANGERS | 11 | 3.21e-01 | 0.173000 | 7.14e-01 |
| REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION | 68 | 3.21e-01 | -0.069600 | 7.14e-01 |
| REACTOME ORGANIC ANION TRANSPORTERS | 10 | 3.22e-01 | 0.181000 | 7.14e-01 |
| REACTOME FCERI MEDIATED NF KB ACTIVATION | 78 | 3.22e-01 | -0.064900 | 7.14e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K | 12 | 3.23e-01 | -0.165000 | 7.15e-01 |
| REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA | 63 | 3.23e-01 | -0.072000 | 7.15e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION | 15 | 3.24e-01 | 0.147000 | 7.17e-01 |
| REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS | 8 | 3.28e-01 | 0.200000 | 7.22e-01 |
| REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS | 50 | 3.28e-01 | -0.080000 | 7.22e-01 |
| REACTOME CIPROFLOXACIN ADME | 5 | 3.29e-01 | 0.252000 | 7.24e-01 |
| REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION | 8 | 3.29e-01 | 0.199000 | 7.24e-01 |
| REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | 45 | 3.31e-01 | 0.083800 | 7.24e-01 |
| REACTOME GLUCOCORTICOID BIOSYNTHESIS | 10 | 3.31e-01 | 0.178000 | 7.24e-01 |
| REACTOME SIGNALING BY WNT IN CANCER | 32 | 3.31e-01 | -0.099300 | 7.24e-01 |
| REACTOME METABOLISM OF NUCLEOTIDES | 94 | 3.33e-01 | -0.057800 | 7.27e-01 |
| REACTOME REGULATION OF IFNA IFNB SIGNALING | 23 | 3.33e-01 | 0.117000 | 7.27e-01 |
| REACTOME BETA CATENIN PHOSPHORYLATION CASCADE | 16 | 3.33e-01 | -0.140000 | 7.27e-01 |
| REACTOME LDL CLEARANCE | 19 | 3.35e-01 | -0.128000 | 7.28e-01 |
| REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR | 79 | 3.35e-01 | -0.062700 | 7.28e-01 |
| REACTOME SHC1 EVENTS IN EGFR SIGNALING | 14 | 3.36e-01 | 0.149000 | 7.28e-01 |
| REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS | 7 | 3.36e-01 | -0.210000 | 7.28e-01 |
| REACTOME REGULATION OF IFNG SIGNALING | 14 | 3.36e-01 | 0.148000 | 7.28e-01 |
| REACTOME EPH EPHRIN SIGNALING | 90 | 3.37e-01 | -0.058600 | 7.28e-01 |
| REACTOME SYNTHESIS OF KETONE BODIES | 8 | 3.38e-01 | -0.196000 | 7.29e-01 |
| REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION | 16 | 3.38e-01 | 0.138000 | 7.29e-01 |
| REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 22 | 3.38e-01 | 0.118000 | 7.29e-01 |
| REACTOME TIE2 SIGNALING | 18 | 3.39e-01 | 0.130000 | 7.29e-01 |
| REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY | 26 | 3.39e-01 | -0.108000 | 7.29e-01 |
| REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | 11 | 3.40e-01 | -0.166000 | 7.29e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | 15 | 3.40e-01 | -0.142000 | 7.29e-01 |
| REACTOME RUNX3 REGULATES P14 ARF | 10 | 3.40e-01 | -0.174000 | 7.29e-01 |
| REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH | 9 | 3.41e-01 | -0.183000 | 7.29e-01 |
| REACTOME SIGNALING BY ALK IN CANCER | 53 | 3.43e-01 | 0.075300 | 7.32e-01 |
| REACTOME RHO GTPASES ACTIVATE PKNS | 86 | 3.45e-01 | -0.058800 | 7.36e-01 |
| REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | 16 | 3.46e-01 | 0.136000 | 7.36e-01 |
| REACTOME HIV TRANSCRIPTION INITIATION | 43 | 3.47e-01 | -0.082900 | 7.36e-01 |
| REACTOME DEGRADATION OF AXIN | 54 | 3.47e-01 | -0.074000 | 7.36e-01 |
| REACTOME ION TRANSPORT BY P TYPE ATPASES | 51 | 3.48e-01 | 0.076000 | 7.36e-01 |
| REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS | 10 | 3.48e-01 | -0.171000 | 7.36e-01 |
| REACTOME EXTENSION OF TELOMERES | 49 | 3.49e-01 | -0.077400 | 7.36e-01 |
| REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 | 59 | 3.49e-01 | -0.070500 | 7.36e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES | 15 | 3.49e-01 | -0.140000 | 7.36e-01 |
| REACTOME CHOLINE CATABOLISM | 6 | 3.49e-01 | 0.221000 | 7.36e-01 |
| REACTOME LYSOSOME VESICLE BIOGENESIS | 33 | 3.50e-01 | -0.094000 | 7.36e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | 46 | 3.51e-01 | 0.079500 | 7.37e-01 |
| REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS | 312 | 3.52e-01 | 0.030600 | 7.37e-01 |
| REACTOME PYRUVATE METABOLISM | 29 | 3.53e-01 | -0.099700 | 7.37e-01 |
| REACTOME THYROXINE BIOSYNTHESIS | 10 | 3.53e-01 | 0.170000 | 7.37e-01 |
| REACTOME SPRY REGULATION OF FGF SIGNALING | 16 | 3.54e-01 | 0.134000 | 7.37e-01 |
| REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB | 5 | 3.54e-01 | -0.239000 | 7.37e-01 |
| REACTOME INTERLEUKIN 37 SIGNALING | 20 | 3.55e-01 | 0.119000 | 7.37e-01 |
| REACTOME GRB7 EVENTS IN ERBB2 SIGNALING | 5 | 3.55e-01 | 0.239000 | 7.37e-01 |
| REACTOME RND1 GTPASE CYCLE | 41 | 3.56e-01 | -0.083300 | 7.37e-01 |
| REACTOME SIALIC ACID METABOLISM | 33 | 3.56e-01 | 0.092800 | 7.37e-01 |
| REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 25 | 3.56e-01 | 0.107000 | 7.37e-01 |
| REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN | 35 | 3.57e-01 | -0.090000 | 7.37e-01 |
| REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS | 33 | 3.57e-01 | -0.092600 | 7.37e-01 |
| REACTOME VITAMIN D CALCIFEROL METABOLISM | 12 | 3.58e-01 | 0.153000 | 7.37e-01 |
| REACTOME GP1B IX V ACTIVATION SIGNALLING | 11 | 3.58e-01 | 0.160000 | 7.37e-01 |
| REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION | 19 | 3.58e-01 | 0.122000 | 7.37e-01 |
| REACTOME GLYCOSPHINGOLIPID METABOLISM | 39 | 3.58e-01 | -0.085100 | 7.37e-01 |
| REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS | 7 | 3.58e-01 | -0.201000 | 7.37e-01 |
| REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE | 52 | 3.59e-01 | -0.073600 | 7.37e-01 |
| REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING | 34 | 3.59e-01 | 0.090900 | 7.37e-01 |
| REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS | 53 | 3.60e-01 | -0.072700 | 7.37e-01 |
| REACTOME VEGFR2 MEDIATED CELL PROLIFERATION | 19 | 3.62e-01 | -0.121000 | 7.38e-01 |
| REACTOME PEROXISOMAL PROTEIN IMPORT | 62 | 3.62e-01 | 0.066900 | 7.38e-01 |
| REACTOME SIGNALING BY KIT IN DISEASE | 20 | 3.62e-01 | 0.118000 | 7.38e-01 |
| REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 | 12 | 3.63e-01 | -0.152000 | 7.38e-01 |
| REACTOME INTERLEUKIN 20 FAMILY SIGNALING | 25 | 3.63e-01 | 0.105000 | 7.38e-01 |
| REACTOME GLYCOLYSIS | 70 | 3.63e-01 | -0.062900 | 7.38e-01 |
| REACTOME CHYLOMICRON ASSEMBLY | 10 | 3.63e-01 | 0.166000 | 7.38e-01 |
| REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | 30 | 3.64e-01 | -0.095800 | 7.38e-01 |
| REACTOME G1 S DNA DAMAGE CHECKPOINTS | 67 | 3.65e-01 | -0.064000 | 7.40e-01 |
| REACTOME SIGNALING BY ERYTHROPOIETIN | 25 | 3.67e-01 | 0.104000 | 7.43e-01 |
| REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS | 15 | 3.68e-01 | -0.134000 | 7.43e-01 |
| REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN | 19 | 3.68e-01 | -0.119000 | 7.43e-01 |
| REACTOME TRANSPORT OF RCBL WITHIN THE BODY | 8 | 3.69e-01 | -0.184000 | 7.43e-01 |
| REACTOME SULFIDE OXIDATION TO SULFATE | 6 | 3.69e-01 | -0.212000 | 7.43e-01 |
| REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS | 28 | 3.69e-01 | 0.098000 | 7.43e-01 |
| REACTOME SELENOAMINO ACID METABOLISM | 108 | 3.70e-01 | 0.049900 | 7.44e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION | 89 | 3.71e-01 | -0.054900 | 7.44e-01 |
| REACTOME GLYCEROPHOSPHOLIPID CATABOLISM | 7 | 3.72e-01 | 0.195000 | 7.44e-01 |
| REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER | 81 | 3.72e-01 | -0.057400 | 7.44e-01 |
| REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX | 29 | 3.72e-01 | -0.095700 | 7.44e-01 |
| REACTOME DUAL INCISION IN TC NER | 63 | 3.73e-01 | -0.064800 | 7.45e-01 |
| REACTOME KEAP1 NFE2L2 PATHWAY | 104 | 3.74e-01 | -0.050500 | 7.45e-01 |
| REACTOME RRNA PROCESSING | 192 | 3.74e-01 | -0.037200 | 7.45e-01 |
| REACTOME SIGNALING BY EGFR | 49 | 3.75e-01 | 0.073200 | 7.46e-01 |
| REACTOME ABACAVIR ADME | 9 | 3.76e-01 | 0.171000 | 7.46e-01 |
| REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR | 21 | 3.76e-01 | -0.112000 | 7.47e-01 |
| REACTOME HYALURONAN METABOLISM | 17 | 3.78e-01 | -0.124000 | 7.48e-01 |
| REACTOME NUCLEOTIDE SALVAGE | 21 | 3.78e-01 | 0.111000 | 7.48e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | 35 | 3.78e-01 | -0.086100 | 7.48e-01 |
| REACTOME STABILIZATION OF P53 | 56 | 3.80e-01 | -0.067800 | 7.51e-01 |
| REACTOME INFECTIOUS DISEASE | 910 | 3.81e-01 | -0.017100 | 7.52e-01 |
| REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY | 5 | 3.82e-01 | 0.226000 | 7.52e-01 |
| REACTOME INTERLEUKIN 36 PATHWAY | 7 | 3.82e-01 | 0.191000 | 7.52e-01 |
| REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS | 9 | 3.83e-01 | 0.168000 | 7.52e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | 17 | 3.83e-01 | -0.122000 | 7.52e-01 |
| REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 29 | 3.84e-01 | 0.093500 | 7.53e-01 |
| REACTOME CYTOSOLIC TRNA AMINOACYLATION | 22 | 3.85e-01 | -0.107000 | 7.54e-01 |
| REACTOME LYSINE CATABOLISM | 12 | 3.87e-01 | -0.144000 | 7.58e-01 |
| REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | 28 | 3.88e-01 | -0.094300 | 7.58e-01 |
| REACTOME HDR THROUGH MMEJ ALT NHEJ | 12 | 3.88e-01 | -0.144000 | 7.58e-01 |
| REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION | 21 | 3.89e-01 | -0.108000 | 7.58e-01 |
| REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS | 19 | 3.90e-01 | -0.114000 | 7.58e-01 |
| REACTOME ARMS MEDIATED ACTIVATION | 7 | 3.90e-01 | -0.188000 | 7.58e-01 |
| REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | 16 | 3.90e-01 | 0.124000 | 7.58e-01 |
| REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT | 18 | 3.92e-01 | -0.117000 | 7.60e-01 |
| REACTOME SIGNALING BY PDGFR IN DISEASE | 20 | 3.93e-01 | -0.110000 | 7.61e-01 |
| REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME | 59 | 3.93e-01 | -0.064300 | 7.61e-01 |
| REACTOME PROCESSING OF SMDT1 | 16 | 3.94e-01 | -0.123000 | 7.61e-01 |
| REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME | 11 | 3.96e-01 | -0.148000 | 7.65e-01 |
| REACTOME SIGNALING BY NTRK2 TRKB | 25 | 3.96e-01 | 0.098000 | 7.65e-01 |
| REACTOME DARPP 32 EVENTS | 24 | 3.97e-01 | 0.099900 | 7.65e-01 |
| REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES | 6 | 4.00e-01 | 0.198000 | 7.70e-01 |
| REACTOME RRNA PROCESSING IN THE MITOCHONDRION | 9 | 4.00e-01 | -0.162000 | 7.70e-01 |
| REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL | 14 | 4.02e-01 | 0.129000 | 7.71e-01 |
| REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | 17 | 4.02e-01 | 0.117000 | 7.71e-01 |
| REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY | 84 | 4.03e-01 | -0.052800 | 7.71e-01 |
| REACTOME BASE EXCISION REPAIR | 87 | 4.04e-01 | -0.051800 | 7.73e-01 |
| REACTOME MICRORNA MIRNA BIOGENESIS | 25 | 4.05e-01 | -0.096300 | 7.74e-01 |
| REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS | 10 | 4.05e-01 | 0.152000 | 7.74e-01 |
| REACTOME RECEPTOR MEDIATED MITOPHAGY | 10 | 4.06e-01 | -0.152000 | 7.74e-01 |
| REACTOME RIPK1 MEDIATED REGULATED NECROSIS | 30 | 4.07e-01 | 0.087600 | 7.74e-01 |
| REACTOME RAB REGULATION OF TRAFFICKING | 110 | 4.07e-01 | -0.045800 | 7.75e-01 |
| REACTOME TRANSPORT AND SYNTHESIS OF PAPS | 6 | 4.08e-01 | 0.195000 | 7.75e-01 |
| REACTOME PI3K AKT SIGNALING IN CANCER | 103 | 4.09e-01 | 0.047100 | 7.76e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE | 5 | 4.12e-01 | 0.212000 | 7.78e-01 |
| REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION | 5 | 4.12e-01 | 0.212000 | 7.78e-01 |
| REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS | 8 | 4.12e-01 | -0.167000 | 7.78e-01 |
| REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND | 9 | 4.12e-01 | 0.158000 | 7.78e-01 |
| REACTOME BIOSYNTHESIS OF MARESINS | 8 | 4.13e-01 | 0.167000 | 7.78e-01 |
| REACTOME FCGR ACTIVATION | 11 | 4.13e-01 | 0.142000 | 7.78e-01 |
| REACTOME MYD88 INDEPENDENT TLR4 CASCADE | 103 | 4.14e-01 | -0.046600 | 7.78e-01 |
| REACTOME TRANSLESION SYNTHESIS BY POLH | 19 | 4.14e-01 | -0.108000 | 7.78e-01 |
| REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA | 15 | 4.15e-01 | 0.122000 | 7.80e-01 |
| REACTOME LATE ENDOSOMAL MICROAUTOPHAGY | 33 | 4.16e-01 | 0.081900 | 7.80e-01 |
| REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS | 13 | 4.16e-01 | 0.130000 | 7.80e-01 |
| REACTOME NRAGE SIGNALS DEATH THROUGH JNK | 53 | 4.17e-01 | 0.064500 | 7.80e-01 |
| REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX | 57 | 4.17e-01 | -0.062100 | 7.80e-01 |
| REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION | 35 | 4.18e-01 | 0.079200 | 7.80e-01 |
| REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | 123 | 4.19e-01 | 0.042200 | 7.81e-01 |
| REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | 15 | 4.19e-01 | 0.121000 | 7.81e-01 |
| REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | 23 | 4.20e-01 | 0.097200 | 7.81e-01 |
| REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA | 28 | 4.22e-01 | -0.087600 | 7.82e-01 |
| REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | 11 | 4.22e-01 | 0.140000 | 7.82e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE | 74 | 4.23e-01 | 0.053900 | 7.82e-01 |
| REACTOME INOSITOL PHOSPHATE METABOLISM | 45 | 4.23e-01 | 0.069100 | 7.82e-01 |
| REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 44 | 4.24e-01 | -0.069700 | 7.82e-01 |
| REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | 99 | 4.24e-01 | 0.046500 | 7.82e-01 |
| REACTOME RHO GTPASE CYCLE | 423 | 4.24e-01 | -0.022700 | 7.82e-01 |
| REACTOME MRNA EDITING | 10 | 4.24e-01 | 0.146000 | 7.82e-01 |
| REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION | 5 | 4.24e-01 | -0.206000 | 7.82e-01 |
| REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS | 299 | 4.25e-01 | -0.026800 | 7.82e-01 |
| REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS | 7 | 4.25e-01 | 0.174000 | 7.82e-01 |
| REACTOME PROTEIN FOLDING | 96 | 4.26e-01 | -0.047000 | 7.82e-01 |
| REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | 24 | 4.26e-01 | -0.093800 | 7.82e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PG | 18 | 4.29e-01 | 0.108000 | 7.85e-01 |
| REACTOME CONJUGATION OF BENZOATE WITH GLYCINE | 6 | 4.29e-01 | 0.187000 | 7.85e-01 |
| REACTOME NEF AND SIGNAL TRANSDUCTION | 8 | 4.31e-01 | -0.161000 | 7.85e-01 |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 70 | 4.31e-01 | -0.054400 | 7.85e-01 |
| REACTOME SYNTHESIS OF PG | 8 | 4.31e-01 | 0.161000 | 7.85e-01 |
| REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS | 7 | 4.32e-01 | -0.172000 | 7.85e-01 |
| REACTOME PHASE 3 RAPID REPOLARISATION | 8 | 4.32e-01 | 0.160000 | 7.85e-01 |
| REACTOME SCAVENGING BY CLASS A RECEPTORS | 19 | 4.32e-01 | 0.104000 | 7.85e-01 |
| REACTOME SEMA4D IN SEMAPHORIN SIGNALING | 24 | 4.32e-01 | 0.092600 | 7.85e-01 |
| REACTOME ROBO RECEPTORS BIND AKAP5 | 9 | 4.33e-01 | -0.151000 | 7.85e-01 |
| REACTOME SIGNALING BY NOTCH | 234 | 4.34e-01 | -0.029700 | 7.85e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING | 6 | 4.34e-01 | 0.184000 | 7.85e-01 |
| REACTOME BASIGIN INTERACTIONS | 24 | 4.35e-01 | 0.092100 | 7.85e-01 |
| REACTOME PROTEIN METHYLATION | 17 | 4.35e-01 | -0.109000 | 7.85e-01 |
| REACTOME NRCAM INTERACTIONS | 6 | 4.35e-01 | 0.184000 | 7.85e-01 |
| REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA | 5 | 4.37e-01 | -0.201000 | 7.87e-01 |
| REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY | 30 | 4.38e-01 | -0.081700 | 7.88e-01 |
| REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN | 5 | 4.39e-01 | -0.200000 | 7.88e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX | 91 | 4.39e-01 | -0.047000 | 7.88e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST | 18 | 4.42e-01 | -0.105000 | 7.92e-01 |
| REACTOME RAC3 GTPASE CYCLE | 85 | 4.42e-01 | -0.048200 | 7.92e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | 11 | 4.42e-01 | -0.134000 | 7.92e-01 |
| REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS | 14 | 4.44e-01 | -0.118000 | 7.94e-01 |
| REACTOME MHC CLASS II ANTIGEN PRESENTATION | 121 | 4.45e-01 | -0.040200 | 7.95e-01 |
| REACTOME LINOLEIC ACID LA METABOLISM | 7 | 4.46e-01 | -0.166000 | 7.95e-01 |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 35 | 4.47e-01 | 0.074300 | 7.95e-01 |
| REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | 11 | 4.47e-01 | 0.133000 | 7.95e-01 |
| REACTOME TELOMERE MAINTENANCE | 106 | 4.48e-01 | -0.042700 | 7.96e-01 |
| REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | 22 | 4.48e-01 | 0.093400 | 7.96e-01 |
| REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS | 26 | 4.49e-01 | -0.085700 | 7.97e-01 |
| REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 29 | 4.50e-01 | -0.081100 | 7.97e-01 |
| REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS | 9 | 4.52e-01 | -0.145000 | 8.00e-01 |
| REACTOME TELOMERE EXTENSION BY TELOMERASE | 22 | 4.52e-01 | -0.092600 | 8.00e-01 |
| REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA | 5 | 4.53e-01 | -0.194000 | 8.01e-01 |
| REACTOME METALLOPROTEASE DUBS | 36 | 4.53e-01 | -0.072200 | 8.01e-01 |
| REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS | 29 | 4.55e-01 | 0.080100 | 8.02e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER | 25 | 4.56e-01 | -0.086100 | 8.02e-01 |
| REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS | 6 | 4.56e-01 | -0.176000 | 8.02e-01 |
| REACTOME REGULATION OF KIT SIGNALING | 16 | 4.57e-01 | 0.107000 | 8.02e-01 |
| REACTOME MET INTERACTS WITH TNS PROTEINS | 5 | 4.57e-01 | 0.192000 | 8.02e-01 |
| REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS | 19 | 4.57e-01 | 0.098500 | 8.02e-01 |
| REACTOME TBC RABGAPS | 40 | 4.58e-01 | -0.067700 | 8.03e-01 |
| REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS | 7 | 4.60e-01 | -0.161000 | 8.05e-01 |
| REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL | 13 | 4.61e-01 | 0.118000 | 8.06e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES STAT5 | 7 | 4.62e-01 | -0.161000 | 8.07e-01 |
| REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT | 23 | 4.62e-01 | -0.088600 | 8.07e-01 |
| REACTOME LEISHMANIA INFECTION | 156 | 4.64e-01 | 0.034000 | 8.08e-01 |
| REACTOME RHO GTPASES ACTIVATE KTN1 | 11 | 4.65e-01 | 0.127000 | 8.09e-01 |
| REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION | 5 | 4.65e-01 | -0.189000 | 8.09e-01 |
| REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | 13 | 4.66e-01 | 0.117000 | 8.09e-01 |
| REACTOME POLYMERASE SWITCHING | 13 | 4.67e-01 | -0.117000 | 8.09e-01 |
| REACTOME NEGATIVE REGULATION OF MET ACTIVITY | 20 | 4.67e-01 | 0.094000 | 8.09e-01 |
| REACTOME BILE ACID AND BILE SALT METABOLISM | 45 | 4.69e-01 | 0.062300 | 8.12e-01 |
| REACTOME TRNA AMINOACYLATION | 40 | 4.70e-01 | -0.066100 | 8.12e-01 |
| REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | 11 | 4.71e-01 | 0.126000 | 8.13e-01 |
| REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | 11 | 4.71e-01 | 0.125000 | 8.13e-01 |
| REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION | 26 | 4.72e-01 | -0.081500 | 8.13e-01 |
| REACTOME DAG AND IP3 SIGNALING | 40 | 4.73e-01 | 0.065600 | 8.13e-01 |
| REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS | 55 | 4.73e-01 | -0.056000 | 8.13e-01 |
| REACTOME GAP JUNCTION DEGRADATION | 12 | 4.75e-01 | 0.119000 | 8.16e-01 |
| REACTOME DEFECTIVE CHSY1 CAUSES TPBS | 7 | 4.76e-01 | 0.156000 | 8.16e-01 |
| REACTOME POTENTIAL THERAPEUTICS FOR SARS | 92 | 4.76e-01 | 0.043000 | 8.16e-01 |
| REACTOME EPHB MEDIATED FORWARD SIGNALING | 41 | 4.76e-01 | 0.064300 | 8.16e-01 |
| REACTOME SENSING OF DNA DOUBLE STRAND BREAKS | 6 | 4.77e-01 | -0.168000 | 8.16e-01 |
| REACTOME NTRK2 ACTIVATES RAC1 | 5 | 4.77e-01 | -0.183000 | 8.16e-01 |
| REACTOME CLEC7A DECTIN 1 SIGNALING | 97 | 4.78e-01 | -0.041700 | 8.16e-01 |
| REACTOME TRANSPORT OF NUCLEOTIDE SUGARS | 8 | 4.78e-01 | 0.145000 | 8.16e-01 |
| REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS | 25 | 4.79e-01 | 0.081800 | 8.17e-01 |
| REACTOME INTERLEUKIN 1 SIGNALING | 110 | 4.80e-01 | -0.039000 | 8.17e-01 |
| REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING | 25 | 4.81e-01 | 0.081500 | 8.17e-01 |
| REACTOME PI5P REGULATES TP53 ACETYLATION | 9 | 4.81e-01 | -0.136000 | 8.17e-01 |
| REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 4.82e-01 | 0.082900 | 8.18e-01 |
| REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER | 5 | 4.83e-01 | 0.181000 | 8.20e-01 |
| REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB | 10 | 4.86e-01 | 0.127000 | 8.24e-01 |
| REACTOME FREE FATTY ACID RECEPTORS | 5 | 4.87e-01 | 0.180000 | 8.24e-01 |
| REACTOME PHASE 2 PLATEAU PHASE | 14 | 4.88e-01 | 0.107000 | 8.24e-01 |
| REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS | 8 | 4.88e-01 | -0.141000 | 8.24e-01 |
| REACTOME HEMOSTASIS | 591 | 4.89e-01 | 0.016700 | 8.24e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG | 7 | 4.89e-01 | -0.151000 | 8.24e-01 |
| REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS | 17 | 4.90e-01 | -0.096800 | 8.24e-01 |
| REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION | 22 | 4.91e-01 | -0.084800 | 8.26e-01 |
| REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS | 12 | 4.92e-01 | -0.115000 | 8.27e-01 |
| REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX | 32 | 4.94e-01 | -0.069800 | 8.29e-01 |
| REACTOME SARS COV 1 INFECTION | 136 | 4.94e-01 | -0.034000 | 8.29e-01 |
| REACTOME GLYCOGEN STORAGE DISEASES | 15 | 4.95e-01 | 0.102000 | 8.29e-01 |
| REACTOME FIBRONECTIN MATRIX FORMATION | 6 | 4.95e-01 | 0.161000 | 8.29e-01 |
| REACTOME RHOQ GTPASE CYCLE | 57 | 4.96e-01 | -0.052100 | 8.30e-01 |
| REACTOME SUMO IS PROTEOLYTICALLY PROCESSED | 6 | 4.97e-01 | -0.160000 | 8.30e-01 |
| REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER | 7 | 4.98e-01 | -0.148000 | 8.30e-01 |
| REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | 26 | 4.98e-01 | -0.076700 | 8.30e-01 |
| REACTOME RRNA MODIFICATION IN THE MITOCHONDRION | 6 | 4.99e-01 | -0.159000 | 8.31e-01 |
| REACTOME METHYLATION | 14 | 5.00e-01 | 0.104000 | 8.33e-01 |
| REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | 27 | 5.03e-01 | 0.074500 | 8.35e-01 |
| REACTOME VITAMIN C ASCORBATE METABOLISM | 8 | 5.04e-01 | 0.137000 | 8.35e-01 |
| REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO | 10 | 5.04e-01 | 0.122000 | 8.35e-01 |
| REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX | 13 | 5.05e-01 | -0.107000 | 8.35e-01 |
| REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION | 20 | 5.05e-01 | 0.086100 | 8.35e-01 |
| REACTOME RAS PROCESSING | 22 | 5.06e-01 | -0.082000 | 8.35e-01 |
| REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION | 7 | 5.06e-01 | 0.145000 | 8.35e-01 |
| REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | 10 | 5.07e-01 | -0.121000 | 8.36e-01 |
| REACTOME FLT3 SIGNALING IN DISEASE | 28 | 5.07e-01 | 0.072500 | 8.36e-01 |
| REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT | 23 | 5.08e-01 | -0.079700 | 8.37e-01 |
| REACTOME DNA STRAND ELONGATION | 31 | 5.12e-01 | -0.068100 | 8.40e-01 |
| REACTOME HDL CLEARANCE | 5 | 5.12e-01 | -0.169000 | 8.40e-01 |
| REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | 51 | 5.13e-01 | -0.052900 | 8.40e-01 |
| REACTOME INACTIVATION OF CDC42 AND RAC1 | 8 | 5.14e-01 | 0.133000 | 8.40e-01 |
| REACTOME DEGRADATION OF DVL | 56 | 5.14e-01 | -0.050400 | 8.40e-01 |
| REACTOME TELOMERE C STRAND SYNTHESIS INITIATION | 12 | 5.14e-01 | -0.109000 | 8.40e-01 |
| REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM | 23 | 5.15e-01 | -0.078500 | 8.40e-01 |
| REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES | 21 | 5.16e-01 | 0.081900 | 8.40e-01 |
| REACTOME DUAL INCISION IN GG NER | 39 | 5.16e-01 | -0.060100 | 8.40e-01 |
| REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN | 15 | 5.16e-01 | -0.096900 | 8.40e-01 |
| REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE | 19 | 5.17e-01 | -0.085900 | 8.40e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE | 19 | 5.17e-01 | -0.085800 | 8.40e-01 |
| REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | 21 | 5.18e-01 | -0.081500 | 8.40e-01 |
| REACTOME INTERFERON GAMMA SIGNALING | 88 | 5.18e-01 | 0.039900 | 8.40e-01 |
| REACTOME MET ACTIVATES PI3K AKT SIGNALING | 6 | 5.19e-01 | 0.152000 | 8.40e-01 |
| REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION | 5 | 5.19e-01 | -0.167000 | 8.40e-01 |
| REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES | 34 | 5.19e-01 | 0.063900 | 8.40e-01 |
| REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | 12 | 5.20e-01 | -0.107000 | 8.42e-01 |
| REACTOME RHOD GTPASE CYCLE | 49 | 5.23e-01 | -0.052700 | 8.43e-01 |
| REACTOME INTERLEUKIN 6 FAMILY SIGNALING | 24 | 5.24e-01 | 0.075100 | 8.43e-01 |
| REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION | 32 | 5.24e-01 | -0.065000 | 8.43e-01 |
| REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS | 14 | 5.25e-01 | -0.098200 | 8.43e-01 |
| REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES | 39 | 5.25e-01 | 0.058900 | 8.43e-01 |
| REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 | 13 | 5.25e-01 | -0.102000 | 8.43e-01 |
| REACTOME SARS COV 2 INFECTION | 281 | 5.25e-01 | -0.022000 | 8.43e-01 |
| REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE | 109 | 5.26e-01 | 0.035200 | 8.43e-01 |
| REACTOME TRANSCRIPTION OF THE HIV GENOME | 66 | 5.26e-01 | -0.045100 | 8.43e-01 |
| REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | 29 | 5.26e-01 | -0.068000 | 8.43e-01 |
| REACTOME HDACS DEACETYLATE HISTONES | 85 | 5.28e-01 | -0.039600 | 8.45e-01 |
| REACTOME RHO GTPASES ACTIVATE CIT | 19 | 5.29e-01 | -0.083500 | 8.45e-01 |
| REACTOME SIGNALING BY NOTCH3 | 48 | 5.29e-01 | 0.052600 | 8.45e-01 |
| REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R | 9 | 5.30e-01 | 0.121000 | 8.46e-01 |
| REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS | 29 | 5.30e-01 | 0.067300 | 8.46e-01 |
| REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS | 6 | 5.31e-01 | 0.148000 | 8.46e-01 |
| REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY | 10 | 5.32e-01 | 0.114000 | 8.47e-01 |
| REACTOME MITOCHONDRIAL PROTEIN IMPORT | 58 | 5.38e-01 | -0.046800 | 8.53e-01 |
| REACTOME DISSOLUTION OF FIBRIN CLOT | 13 | 5.38e-01 | -0.098600 | 8.53e-01 |
| REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE | 29 | 5.39e-01 | -0.066000 | 8.53e-01 |
| REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS | 20 | 5.39e-01 | -0.079300 | 8.53e-01 |
| REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS | 170 | 5.40e-01 | 0.027200 | 8.53e-01 |
| REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING | 13 | 5.41e-01 | -0.097900 | 8.53e-01 |
| REACTOME ANTIGEN PROCESSING CROSS PRESENTATION | 98 | 5.41e-01 | 0.035700 | 8.53e-01 |
| REACTOME SIGNALING BY FGFR1 | 49 | 5.42e-01 | 0.050400 | 8.53e-01 |
| REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D | 8 | 5.42e-01 | 0.125000 | 8.53e-01 |
| REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS | 7 | 5.42e-01 | -0.133000 | 8.53e-01 |
| REACTOME ACYL CHAIN REMODELLING OF PE | 29 | 5.42e-01 | 0.065400 | 8.53e-01 |
| REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK | 28 | 5.43e-01 | -0.066500 | 8.53e-01 |
| REACTOME SIGNALING BY MST1 | 5 | 5.43e-01 | 0.157000 | 8.53e-01 |
| REACTOME SIGNALING BY NTRK3 TRKC | 17 | 5.44e-01 | 0.085000 | 8.53e-01 |
| REACTOME PHYSIOLOGICAL FACTORS | 14 | 5.44e-01 | -0.093600 | 8.53e-01 |
| REACTOME ALPHA DEFENSINS | 6 | 5.47e-01 | 0.142000 | 8.57e-01 |
| REACTOME FASL CD95L SIGNALING | 5 | 5.48e-01 | -0.155000 | 8.57e-01 |
| REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 19 | 5.48e-01 | -0.079600 | 8.57e-01 |
| REACTOME RHOBTB1 GTPASE CYCLE | 22 | 5.50e-01 | -0.073600 | 8.60e-01 |
| REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS | 29 | 5.53e-01 | -0.063700 | 8.61e-01 |
| REACTOME UNWINDING OF DNA | 12 | 5.53e-01 | -0.098900 | 8.61e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS | 9 | 5.53e-01 | 0.114000 | 8.61e-01 |
| REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | 16 | 5.54e-01 | -0.085400 | 8.61e-01 |
| REACTOME ORGANIC CATION TRANSPORT | 10 | 5.56e-01 | -0.108000 | 8.61e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING | 5 | 5.56e-01 | -0.152000 | 8.61e-01 |
| REACTOME EGFR DOWNREGULATION | 30 | 5.56e-01 | 0.062100 | 8.61e-01 |
| REACTOME CLATHRIN MEDIATED ENDOCYTOSIS | 139 | 5.57e-01 | -0.028900 | 8.61e-01 |
| REACTOME SIGNALING BY FGFR1 IN DISEASE | 38 | 5.57e-01 | 0.055000 | 8.61e-01 |
| REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION | 9 | 5.58e-01 | 0.113000 | 8.61e-01 |
| REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 59 | 5.58e-01 | -0.044100 | 8.61e-01 |
| REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS | 19 | 5.58e-01 | 0.077600 | 8.61e-01 |
| REACTOME SYNTHESIS OF PE | 13 | 5.59e-01 | -0.093600 | 8.61e-01 |
| REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | 80 | 5.59e-01 | -0.037800 | 8.61e-01 |
| REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS | 83 | 5.60e-01 | 0.037000 | 8.61e-01 |
| REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | 18 | 5.60e-01 | 0.079300 | 8.61e-01 |
| REACTOME INSULIN PROCESSING | 24 | 5.61e-01 | 0.068600 | 8.61e-01 |
| REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | 69 | 5.63e-01 | 0.040300 | 8.61e-01 |
| REACTOME EPHRIN SIGNALING | 17 | 5.63e-01 | -0.081100 | 8.61e-01 |
| REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX | 15 | 5.63e-01 | -0.086300 | 8.61e-01 |
| REACTOME THE PHOTOTRANSDUCTION CASCADE | 32 | 5.63e-01 | 0.059100 | 8.61e-01 |
| REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION | 10 | 5.63e-01 | 0.106000 | 8.61e-01 |
| REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS | 17 | 5.64e-01 | 0.080900 | 8.61e-01 |
| REACTOME RAC2 GTPASE CYCLE | 81 | 5.64e-01 | -0.037100 | 8.61e-01 |
| REACTOME SPHINGOLIPID METABOLISM | 84 | 5.64e-01 | -0.036400 | 8.61e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS | 15 | 5.65e-01 | -0.085800 | 8.61e-01 |
| REACTOME NONCANONICAL ACTIVATION OF NOTCH3 | 8 | 5.66e-01 | -0.117000 | 8.62e-01 |
| REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A | 5 | 5.67e-01 | 0.148000 | 8.62e-01 |
| REACTOME FGFR2B LIGAND BINDING AND ACTIVATION | 10 | 5.67e-01 | 0.105000 | 8.62e-01 |
| REACTOME SYNTHESIS OF PI | 5 | 5.68e-01 | -0.147000 | 8.63e-01 |
| REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE | 5 | 5.69e-01 | -0.147000 | 8.63e-01 |
| REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS | 22 | 5.71e-01 | 0.069800 | 8.65e-01 |
| REACTOME EARLY PHASE OF HIV LIFE CYCLE | 14 | 5.71e-01 | -0.087500 | 8.65e-01 |
| REACTOME ER QUALITY CONTROL COMPARTMENT ERQC | 21 | 5.72e-01 | -0.071200 | 8.65e-01 |
| REACTOME REGULATION OF FZD BY UBIQUITINATION | 21 | 5.73e-01 | 0.071100 | 8.65e-01 |
| REACTOME ACTIVATION OF C3 AND C5 | 6 | 5.73e-01 | -0.133000 | 8.65e-01 |
| REACTOME SLC TRANSPORTER DISORDERS | 94 | 5.73e-01 | 0.033600 | 8.65e-01 |
| REACTOME UBIQUINOL BIOSYNTHESIS | 8 | 5.74e-01 | 0.115000 | 8.66e-01 |
| REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION | 30 | 5.75e-01 | -0.059100 | 8.67e-01 |
| REACTOME MTOR SIGNALLING | 40 | 5.76e-01 | -0.051100 | 8.67e-01 |
| REACTOME RELEASE OF HH NP FROM THE SECRETING CELL | 8 | 5.76e-01 | 0.114000 | 8.67e-01 |
| REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS | 18 | 5.77e-01 | 0.075900 | 8.67e-01 |
| REACTOME SIGNALING BY FGFR4 IN DISEASE | 11 | 5.78e-01 | 0.096900 | 8.67e-01 |
| REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 5.79e-01 | -0.077800 | 8.67e-01 |
| REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 5.79e-01 | -0.101000 | 8.67e-01 |
| REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION | 27 | 5.79e-01 | -0.061600 | 8.67e-01 |
| REACTOME RNA POLYMERASE III CHAIN ELONGATION | 18 | 5.80e-01 | -0.075300 | 8.67e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K | 7 | 5.80e-01 | 0.121000 | 8.67e-01 |
| REACTOME RECYCLING OF EIF2 GDP | 7 | 5.82e-01 | -0.120000 | 8.67e-01 |
| REACTOME PURINE SALVAGE | 12 | 5.82e-01 | -0.091900 | 8.67e-01 |
| REACTOME SERINE BIOSYNTHESIS | 9 | 5.82e-01 | -0.106000 | 8.67e-01 |
| REACTOME HEME BIOSYNTHESIS | 13 | 5.83e-01 | -0.088000 | 8.67e-01 |
| REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | 14 | 5.83e-01 | 0.084700 | 8.67e-01 |
| REACTOME INTERLEUKIN 9 SIGNALING | 7 | 5.84e-01 | 0.120000 | 8.67e-01 |
| REACTOME DNA REPLICATION INITIATION | 7 | 5.85e-01 | -0.119000 | 8.68e-01 |
| REACTOME RMTS METHYLATE HISTONE ARGININES | 72 | 5.88e-01 | -0.037000 | 8.71e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS | 9 | 5.88e-01 | -0.104000 | 8.71e-01 |
| REACTOME SIGNALING BY ACTIVIN | 15 | 5.89e-01 | -0.080600 | 8.72e-01 |
| REACTOME PHOSPHORYLATION OF EMI1 | 6 | 5.90e-01 | -0.127000 | 8.73e-01 |
| REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT | 7 | 5.92e-01 | 0.117000 | 8.74e-01 |
| REACTOME ERK MAPK TARGETS | 20 | 5.92e-01 | -0.069200 | 8.74e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES | 43 | 5.94e-01 | -0.047000 | 8.75e-01 |
| REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION | 31 | 5.94e-01 | 0.055400 | 8.75e-01 |
| REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE | 30 | 5.96e-01 | -0.055900 | 8.78e-01 |
| REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS | 9 | 5.97e-01 | 0.102000 | 8.78e-01 |
| REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE | 100 | 6.00e-01 | -0.030400 | 8.82e-01 |
| REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE | 12 | 6.00e-01 | -0.087400 | 8.82e-01 |
| REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | 20 | 6.01e-01 | -0.067500 | 8.82e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING | 30 | 6.02e-01 | 0.055100 | 8.82e-01 |
| REACTOME DERMATAN SULFATE BIOSYNTHESIS | 10 | 6.02e-01 | -0.095300 | 8.82e-01 |
| REACTOME TRAFFICKING OF AMPA RECEPTORS | 29 | 6.02e-01 | -0.055900 | 8.82e-01 |
| REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | 20 | 6.04e-01 | 0.066900 | 8.82e-01 |
| REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | 46 | 6.04e-01 | -0.044100 | 8.82e-01 |
| REACTOME SIGNALLING TO ERKS | 34 | 6.05e-01 | 0.051300 | 8.82e-01 |
| REACTOME P38MAPK EVENTS | 13 | 6.05e-01 | 0.082800 | 8.82e-01 |
| REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | 122 | 6.05e-01 | 0.027100 | 8.82e-01 |
| REACTOME MAPK FAMILY SIGNALING CASCADES | 314 | 6.07e-01 | -0.016900 | 8.83e-01 |
| REACTOME IRS MEDIATED SIGNALLING | 47 | 6.08e-01 | -0.043300 | 8.84e-01 |
| REACTOME FCERI MEDIATED MAPK ACTIVATION | 32 | 6.09e-01 | 0.052200 | 8.85e-01 |
| REACTOME VITAMINS | 6 | 6.10e-01 | -0.120000 | 8.85e-01 |
| REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | 353 | 6.11e-01 | 0.015800 | 8.85e-01 |
| REACTOME VOLTAGE GATED POTASSIUM CHANNELS | 42 | 6.11e-01 | 0.045300 | 8.85e-01 |
| REACTOME ONCOGENIC MAPK SIGNALING | 79 | 6.12e-01 | 0.033100 | 8.85e-01 |
| REACTOME FCERI MEDIATED CA 2 MOBILIZATION | 30 | 6.12e-01 | 0.053500 | 8.85e-01 |
| REACTOME FCGR3A MEDIATED IL10 SYNTHESIS | 36 | 6.13e-01 | 0.048800 | 8.86e-01 |
| REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE | 10 | 6.13e-01 | -0.092300 | 8.86e-01 |
| REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS | 9 | 6.15e-01 | -0.096900 | 8.86e-01 |
| REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION | 23 | 6.15e-01 | -0.060600 | 8.86e-01 |
| REACTOME PHOSPHOLIPID METABOLISM | 201 | 6.15e-01 | 0.020600 | 8.86e-01 |
| REACTOME GLYCOGEN METABOLISM | 22 | 6.16e-01 | 0.061700 | 8.86e-01 |
| REACTOME DOWNREGULATION OF ERBB4 SIGNALING | 9 | 6.17e-01 | 0.096400 | 8.86e-01 |
| REACTOME MTORC1 MEDIATED SIGNALLING | 23 | 6.18e-01 | -0.060100 | 8.87e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS | 8 | 6.18e-01 | 0.102000 | 8.87e-01 |
| REACTOME CLEC7A INFLAMMASOME PATHWAY | 6 | 6.19e-01 | -0.117000 | 8.87e-01 |
| REACTOME ALK MUTANTS BIND TKIS | 12 | 6.19e-01 | 0.082900 | 8.87e-01 |
| REACTOME SIGNALING BY LEPTIN | 11 | 6.21e-01 | -0.086200 | 8.88e-01 |
| REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL | 25 | 6.21e-01 | 0.057100 | 8.88e-01 |
| REACTOME COENZYME A BIOSYNTHESIS | 8 | 6.22e-01 | 0.101000 | 8.88e-01 |
| REACTOME PHENYLALANINE AND TYROSINE METABOLISM | 11 | 6.23e-01 | 0.085700 | 8.88e-01 |
| REACTOME CARGO CONCENTRATION IN THE ER | 32 | 6.23e-01 | -0.050200 | 8.88e-01 |
| REACTOME TRIGLYCERIDE BIOSYNTHESIS | 12 | 6.23e-01 | -0.082000 | 8.88e-01 |
| REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE | 6 | 6.24e-01 | -0.116000 | 8.89e-01 |
| REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL | 8 | 6.25e-01 | 0.099700 | 8.90e-01 |
| REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH | 6 | 6.26e-01 | -0.115000 | 8.90e-01 |
| REACTOME PROLACTIN RECEPTOR SIGNALING | 15 | 6.28e-01 | 0.072300 | 8.92e-01 |
| REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM | 11 | 6.29e-01 | 0.084100 | 8.92e-01 |
| REACTOME REGULATED NECROSIS | 57 | 6.29e-01 | -0.037000 | 8.92e-01 |
| REACTOME NETRIN 1 SIGNALING | 49 | 6.30e-01 | 0.039800 | 8.92e-01 |
| REACTOME RHOC GTPASE CYCLE | 71 | 6.30e-01 | 0.033100 | 8.92e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS | 9 | 6.31e-01 | -0.092600 | 8.92e-01 |
| REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B | 7 | 6.33e-01 | -0.104000 | 8.92e-01 |
| REACTOME TRYPTOPHAN CATABOLISM | 14 | 6.33e-01 | -0.073600 | 8.92e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS | 12 | 6.34e-01 | -0.079400 | 8.92e-01 |
| REACTOME SIGNALING BY NTRKS | 132 | 6.34e-01 | -0.024000 | 8.92e-01 |
| REACTOME SIGNALLING TO RAS | 20 | 6.34e-01 | 0.061500 | 8.92e-01 |
| REACTOME CD209 DC SIGN SIGNALING | 20 | 6.34e-01 | -0.061400 | 8.92e-01 |
| REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | 9 | 6.35e-01 | 0.091500 | 8.92e-01 |
| REACTOME TYROSINE CATABOLISM | 5 | 6.35e-01 | 0.123000 | 8.92e-01 |
| REACTOME NUCLEOTIDE CATABOLISM | 35 | 6.37e-01 | -0.046100 | 8.93e-01 |
| REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS | 122 | 6.37e-01 | -0.024700 | 8.93e-01 |
| REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | 19 | 6.37e-01 | 0.062500 | 8.93e-01 |
| REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | 19 | 6.40e-01 | 0.061900 | 8.96e-01 |
| REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | 14 | 6.42e-01 | -0.071700 | 8.98e-01 |
| REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | 50 | 6.44e-01 | 0.037800 | 9.00e-01 |
| REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES | 6 | 6.45e-01 | 0.109000 | 9.00e-01 |
| REACTOME REGULATION OF NPAS4 GENE EXPRESSION | 13 | 6.46e-01 | -0.073600 | 9.00e-01 |
| REACTOME DIGESTION OF DIETARY CARBOHYDRATE | 6 | 6.46e-01 | 0.108000 | 9.00e-01 |
| REACTOME HS GAG BIOSYNTHESIS | 28 | 6.47e-01 | 0.049900 | 9.00e-01 |
| REACTOME GAP JUNCTION TRAFFICKING AND REGULATION | 49 | 6.49e-01 | -0.037600 | 9.00e-01 |
| REACTOME REPRODUCTION | 136 | 6.49e-01 | -0.022600 | 9.00e-01 |
| REACTOME PI3K AKT ACTIVATION | 9 | 6.49e-01 | -0.087500 | 9.00e-01 |
| REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION | 9 | 6.51e-01 | -0.087100 | 9.00e-01 |
| REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION | 193 | 6.51e-01 | -0.018900 | 9.00e-01 |
| REACTOME DNA DAMAGE RECOGNITION IN GG NER | 36 | 6.51e-01 | -0.043500 | 9.00e-01 |
| REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY | 10 | 6.51e-01 | -0.082500 | 9.00e-01 |
| REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS | 11 | 6.52e-01 | -0.078500 | 9.00e-01 |
| REACTOME BASE EXCISION REPAIR AP SITE FORMATION | 59 | 6.53e-01 | -0.033900 | 9.00e-01 |
| REACTOME P2Y RECEPTORS | 9 | 6.53e-01 | 0.086600 | 9.00e-01 |
| REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | 17 | 6.54e-01 | -0.062800 | 9.00e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS | 8 | 6.54e-01 | 0.091500 | 9.00e-01 |
| REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY | 25 | 6.54e-01 | 0.051800 | 9.00e-01 |
| REACTOME MET ACTIVATES RAS SIGNALING | 11 | 6.55e-01 | 0.077900 | 9.00e-01 |
| REACTOME GLYCOGEN SYNTHESIS | 13 | 6.55e-01 | 0.071600 | 9.00e-01 |
| REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | 86 | 6.55e-01 | -0.027800 | 9.00e-01 |
| REACTOME NEUROTRANSMITTER RELEASE CYCLE | 48 | 6.56e-01 | -0.037100 | 9.01e-01 |
| REACTOME THE NLRP3 INFLAMMASOME | 16 | 6.57e-01 | -0.064100 | 9.01e-01 |
| REACTOME SIGNAL ATTENUATION | 10 | 6.58e-01 | 0.081000 | 9.01e-01 |
| REACTOME METABOLISM OF COFACTORS | 19 | 6.58e-01 | 0.058600 | 9.01e-01 |
| REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE | 63 | 6.58e-01 | -0.032200 | 9.01e-01 |
| REACTOME DSCAM INTERACTIONS | 11 | 6.59e-01 | 0.076800 | 9.01e-01 |
| REACTOME SARS COV 2 HOST INTERACTIONS | 191 | 6.60e-01 | -0.018400 | 9.01e-01 |
| REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA | 8 | 6.60e-01 | 0.089700 | 9.01e-01 |
| REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 | 54 | 6.60e-01 | -0.034600 | 9.01e-01 |
| REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA | 17 | 6.61e-01 | -0.061400 | 9.01e-01 |
| REACTOME PLASMA LIPOPROTEIN CLEARANCE | 37 | 6.62e-01 | -0.041500 | 9.01e-01 |
| REACTOME SIGNAL TRANSDUCTION BY L1 | 20 | 6.63e-01 | 0.056300 | 9.01e-01 |
| REACTOME MISCELLANEOUS SUBSTRATES | 12 | 6.63e-01 | 0.072500 | 9.01e-01 |
| REACTOME CREB3 FACTORS ACTIVATE GENES | 8 | 6.64e-01 | -0.088700 | 9.01e-01 |
| REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY | 33 | 6.64e-01 | 0.043700 | 9.01e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING | 32 | 6.66e-01 | 0.044100 | 9.03e-01 |
| REACTOME SYNTHESIS OF LIPOXINS LX | 6 | 6.69e-01 | -0.101000 | 9.04e-01 |
| REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K | 6 | 6.69e-01 | 0.101000 | 9.04e-01 |
| REACTOME OTHER INTERLEUKIN SIGNALING | 24 | 6.69e-01 | 0.050400 | 9.04e-01 |
| REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | 12 | 6.69e-01 | -0.071300 | 9.04e-01 |
| REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 11 | 6.70e-01 | 0.074200 | 9.04e-01 |
| REACTOME HSF1 DEPENDENT TRANSACTIVATION | 37 | 6.70e-01 | 0.040400 | 9.04e-01 |
| REACTOME SEROTONIN RECEPTORS | 11 | 6.71e-01 | -0.074100 | 9.04e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 | 94 | 6.71e-01 | -0.025300 | 9.04e-01 |
| REACTOME RHOF GTPASE CYCLE | 40 | 6.71e-01 | -0.038800 | 9.04e-01 |
| REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS | 5 | 6.72e-01 | -0.109000 | 9.04e-01 |
| REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR | 19 | 6.72e-01 | 0.056000 | 9.04e-01 |
| REACTOME EARLY SARS COV 2 INFECTION EVENTS | 34 | 6.73e-01 | -0.041800 | 9.04e-01 |
| REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA | 77 | 6.74e-01 | 0.027800 | 9.04e-01 |
| REACTOME FGFR3B LIGAND BINDING AND ACTIVATION | 7 | 6.75e-01 | -0.091500 | 9.05e-01 |
| REACTOME SCAVENGING BY CLASS F RECEPTORS | 6 | 6.75e-01 | -0.098700 | 9.05e-01 |
| REACTOME KERATAN SULFATE BIOSYNTHESIS | 28 | 6.76e-01 | 0.045600 | 9.05e-01 |
| REACTOME VLDLR INTERNALISATION AND DEGRADATION | 16 | 6.79e-01 | -0.059700 | 9.08e-01 |
| REACTOME RA BIOSYNTHESIS PATHWAY | 22 | 6.80e-01 | 0.050800 | 9.08e-01 |
| REACTOME METABOLISM OF STEROID HORMONES | 35 | 6.81e-01 | -0.040100 | 9.08e-01 |
| REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY | 14 | 6.82e-01 | 0.063300 | 9.08e-01 |
| REACTOME HORMONE LIGAND BINDING RECEPTORS | 12 | 6.82e-01 | -0.068400 | 9.08e-01 |
| REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY | 6 | 6.84e-01 | -0.095900 | 9.10e-01 |
| REACTOME RET SIGNALING | 40 | 6.84e-01 | 0.037200 | 9.10e-01 |
| REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS | 27 | 6.88e-01 | -0.044700 | 9.14e-01 |
| REACTOME EFFECTS OF PIP2 HYDROLYSIS | 26 | 6.89e-01 | -0.045400 | 9.14e-01 |
| REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS | 8 | 6.89e-01 | -0.081800 | 9.14e-01 |
| REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE | 9 | 6.89e-01 | 0.077000 | 9.14e-01 |
| REACTOME SIGNALING BY BMP | 27 | 6.90e-01 | -0.044400 | 9.14e-01 |
| REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION | 42 | 6.91e-01 | 0.035500 | 9.15e-01 |
| REACTOME MET RECEPTOR RECYCLING | 10 | 6.91e-01 | 0.072500 | 9.15e-01 |
| REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | 24 | 6.93e-01 | 0.046600 | 9.15e-01 |
| REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS | 5 | 6.93e-01 | -0.102000 | 9.15e-01 |
| REACTOME RHOH GTPASE CYCLE | 37 | 6.93e-01 | -0.037400 | 9.15e-01 |
| REACTOME SIGNALING BY ERBB2 ECD MUTANTS | 16 | 6.93e-01 | 0.056900 | 9.15e-01 |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 30 | 6.94e-01 | -0.041500 | 9.15e-01 |
| REACTOME TNFR2 NON CANONICAL NF KB PATHWAY | 96 | 6.97e-01 | -0.023000 | 9.17e-01 |
| REACTOME DISEASES OF BASE EXCISION REPAIR | 5 | 6.97e-01 | 0.101000 | 9.17e-01 |
| REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | 9 | 6.99e-01 | 0.074500 | 9.17e-01 |
| REACTOME RUNX3 REGULATES WNT SIGNALING | 8 | 6.99e-01 | 0.078900 | 9.17e-01 |
| REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING | 17 | 6.99e-01 | 0.054100 | 9.17e-01 |
| REACTOME SIGNALING BY FGFR2 | 72 | 7.00e-01 | -0.026300 | 9.17e-01 |
| REACTOME RUNX2 REGULATES BONE DEVELOPMENT | 29 | 7.01e-01 | -0.041300 | 9.17e-01 |
| REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN | 13 | 7.01e-01 | -0.061500 | 9.17e-01 |
| REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS | 63 | 7.01e-01 | -0.028000 | 9.17e-01 |
| REACTOME SIGNALING BY FGFR4 | 40 | 7.02e-01 | 0.035000 | 9.17e-01 |
| REACTOME ASPARTATE AND ASPARAGINE METABOLISM | 11 | 7.03e-01 | -0.066500 | 9.17e-01 |
| REACTOME RHOT1 GTPASE CYCLE | 5 | 7.03e-01 | 0.098500 | 9.17e-01 |
| REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN | 45 | 7.04e-01 | -0.032700 | 9.17e-01 |
| REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY | 12 | 7.04e-01 | -0.063300 | 9.17e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS | 7 | 7.05e-01 | -0.082500 | 9.17e-01 |
| REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER | 8 | 7.06e-01 | -0.077000 | 9.17e-01 |
| REACTOME MASTL FACILITATES MITOTIC PROGRESSION | 10 | 7.06e-01 | -0.068900 | 9.17e-01 |
| REACTOME OPSINS | 7 | 7.07e-01 | -0.081900 | 9.17e-01 |
| REACTOME REGULATION OF RAS BY GAPS | 66 | 7.08e-01 | -0.026700 | 9.17e-01 |
| REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER | 76 | 7.08e-01 | -0.024800 | 9.17e-01 |
| REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS | 81 | 7.08e-01 | -0.024000 | 9.17e-01 |
| REACTOME REGULATION BY C FLIP | 11 | 7.09e-01 | 0.065000 | 9.17e-01 |
| REACTOME DEFECTIVE F9 ACTIVATION | 5 | 7.10e-01 | 0.096100 | 9.17e-01 |
| REACTOME CA2 PATHWAY | 62 | 7.11e-01 | 0.027200 | 9.17e-01 |
| REACTOME ATTENUATION PHASE | 27 | 7.11e-01 | -0.041200 | 9.17e-01 |
| REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES | 37 | 7.11e-01 | 0.035200 | 9.17e-01 |
| REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES | 29 | 7.12e-01 | 0.039700 | 9.17e-01 |
| REACTOME PREGNENOLONE BIOSYNTHESIS | 12 | 7.12e-01 | 0.061600 | 9.17e-01 |
| REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | 51 | 7.12e-01 | -0.029900 | 9.17e-01 |
| REACTOME LAGGING STRAND SYNTHESIS | 19 | 7.14e-01 | -0.048600 | 9.19e-01 |
| REACTOME PROCESSING AND ACTIVATION OF SUMO | 10 | 7.15e-01 | -0.066600 | 9.20e-01 |
| REACTOME SYNTHESIS OF PC | 27 | 7.16e-01 | 0.040400 | 9.20e-01 |
| REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | 11 | 7.17e-01 | 0.063100 | 9.20e-01 |
| REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY | 46 | 7.18e-01 | 0.030800 | 9.20e-01 |
| REACTOME VITAMIN B1 THIAMIN METABOLISM | 5 | 7.19e-01 | -0.093000 | 9.20e-01 |
| REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS | 60 | 7.19e-01 | -0.026800 | 9.20e-01 |
| REACTOME CREB PHOSPHORYLATION | 6 | 7.19e-01 | -0.084700 | 9.20e-01 |
| REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | 16 | 7.20e-01 | 0.051700 | 9.20e-01 |
| REACTOME CALNEXIN CALRETICULIN CYCLE | 26 | 7.20e-01 | -0.040600 | 9.20e-01 |
| REACTOME RETINOID CYCLE DISEASE EVENTS | 11 | 7.20e-01 | -0.062300 | 9.20e-01 |
| REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA | 54 | 7.21e-01 | -0.028000 | 9.20e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING | 28 | 7.22e-01 | 0.038900 | 9.20e-01 |
| REACTOME SCAVENGING OF HEME FROM PLASMA | 13 | 7.23e-01 | 0.056900 | 9.20e-01 |
| REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING | 9 | 7.23e-01 | 0.068200 | 9.20e-01 |
| REACTOME LDL REMODELING | 6 | 7.24e-01 | 0.083200 | 9.20e-01 |
| REACTOME MELANIN BIOSYNTHESIS | 5 | 7.24e-01 | 0.091000 | 9.20e-01 |
| REACTOME ACTIVATION OF BH3 ONLY PROTEINS | 30 | 7.25e-01 | 0.037100 | 9.20e-01 |
| REACTOME ADHERENS JUNCTIONS INTERACTIONS | 33 | 7.25e-01 | 0.035400 | 9.20e-01 |
| REACTOME CHYLOMICRON REMODELING | 10 | 7.26e-01 | 0.064100 | 9.20e-01 |
| REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING | 23 | 7.27e-01 | 0.042000 | 9.20e-01 |
| REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION | 41 | 7.27e-01 | -0.031500 | 9.20e-01 |
| REACTOME SARS COV INFECTIONS | 392 | 7.27e-01 | -0.010300 | 9.20e-01 |
| REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS | 7 | 7.28e-01 | -0.075900 | 9.20e-01 |
| REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | 37 | 7.28e-01 | -0.033000 | 9.20e-01 |
| REACTOME GLYCOSAMINOGLYCAN METABOLISM | 118 | 7.29e-01 | 0.018400 | 9.21e-01 |
| REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES | 27 | 7.30e-01 | -0.038300 | 9.21e-01 |
| REACTOME INSULIN RECEPTOR RECYCLING | 29 | 7.31e-01 | 0.036900 | 9.21e-01 |
| REACTOME SIGNALING BY FGFR3 | 39 | 7.31e-01 | 0.031800 | 9.21e-01 |
| REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES | 21 | 7.32e-01 | 0.043200 | 9.21e-01 |
| REACTOME INTESTINAL ABSORPTION | 5 | 7.33e-01 | -0.088000 | 9.22e-01 |
| REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | 26 | 7.35e-01 | 0.038400 | 9.23e-01 |
| REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER | 25 | 7.36e-01 | -0.039000 | 9.24e-01 |
| REACTOME RESOLUTION OF ABASIC SITES AP SITES | 38 | 7.37e-01 | -0.031500 | 9.24e-01 |
| REACTOME IRE1ALPHA ACTIVATES CHAPERONES | 48 | 7.37e-01 | 0.028000 | 9.24e-01 |
| REACTOME CROSSLINKING OF COLLAGEN FIBRILS | 16 | 7.38e-01 | 0.048300 | 9.24e-01 |
| REACTOME CALCINEURIN ACTIVATES NFAT | 9 | 7.39e-01 | -0.064000 | 9.25e-01 |
| REACTOME G2 PHASE | 5 | 7.42e-01 | 0.085200 | 9.26e-01 |
| REACTOME AZATHIOPRINE ADME | 22 | 7.42e-01 | -0.040500 | 9.26e-01 |
| REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION | 21 | 7.43e-01 | -0.041300 | 9.26e-01 |
| REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS | 9 | 7.45e-01 | -0.062700 | 9.26e-01 |
| REACTOME SIGNALING BY THE B CELL RECEPTOR BCR | 106 | 7.45e-01 | -0.018300 | 9.26e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 | 31 | 7.45e-01 | 0.033700 | 9.26e-01 |
| REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | 19 | 7.45e-01 | -0.043100 | 9.26e-01 |
| REACTOME C TYPE LECTIN RECEPTORS CLRS | 136 | 7.46e-01 | -0.016100 | 9.26e-01 |
| REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | 53 | 7.46e-01 | 0.025700 | 9.26e-01 |
| REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES | 7 | 7.49e-01 | 0.069900 | 9.26e-01 |
| REACTOME SIGNALING BY NOTCH4 | 80 | 7.49e-01 | -0.020700 | 9.26e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 | 11 | 7.49e-01 | 0.055600 | 9.26e-01 |
| REACTOME DEVELOPMENTAL BIOLOGY | 1115 | 7.50e-01 | 0.005660 | 9.26e-01 |
| REACTOME TRP CHANNELS | 27 | 7.51e-01 | 0.035300 | 9.26e-01 |
| REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN | 11 | 7.51e-01 | -0.055200 | 9.26e-01 |
| REACTOME INFLAMMASOMES | 21 | 7.51e-01 | -0.039900 | 9.26e-01 |
| REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN | 13 | 7.52e-01 | 0.050600 | 9.26e-01 |
| REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION | 13 | 7.53e-01 | 0.050500 | 9.26e-01 |
| REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS | 5 | 7.53e-01 | 0.081300 | 9.26e-01 |
| REACTOME CARNITINE METABOLISM | 13 | 7.54e-01 | -0.050200 | 9.26e-01 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP | 12 | 7.55e-01 | -0.052100 | 9.26e-01 |
| REACTOME UREA CYCLE | 9 | 7.55e-01 | 0.060100 | 9.26e-01 |
| REACTOME PI METABOLISM | 79 | 7.56e-01 | -0.020200 | 9.26e-01 |
| REACTOME FRS MEDIATED FGFR2 SIGNALING | 24 | 7.56e-01 | -0.036600 | 9.26e-01 |
| REACTOME FGFR2 LIGAND BINDING AND ACTIVATION | 19 | 7.57e-01 | -0.041000 | 9.26e-01 |
| REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 | 77 | 7.60e-01 | -0.020200 | 9.26e-01 |
| REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | 15 | 7.60e-01 | -0.045500 | 9.26e-01 |
| REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS | 24 | 7.60e-01 | -0.036000 | 9.26e-01 |
| REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT | 5 | 7.61e-01 | 0.078400 | 9.26e-01 |
| REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD | 5 | 7.62e-01 | -0.078200 | 9.26e-01 |
| REACTOME PEXOPHAGY | 11 | 7.62e-01 | 0.052700 | 9.26e-01 |
| REACTOME TRAIL SIGNALING | 8 | 7.63e-01 | 0.061700 | 9.26e-01 |
| REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES | 34 | 7.63e-01 | 0.029900 | 9.26e-01 |
| REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS | 11 | 7.63e-01 | 0.052400 | 9.26e-01 |
| REACTOME SIGNALING BY ALK | 26 | 7.64e-01 | 0.034000 | 9.26e-01 |
| REACTOME REGULATION OF PTEN LOCALIZATION | 8 | 7.65e-01 | 0.061100 | 9.26e-01 |
| REACTOME FGFR3 LIGAND BINDING AND ACTIVATION | 12 | 7.65e-01 | -0.049800 | 9.26e-01 |
| REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY | 17 | 7.65e-01 | -0.041900 | 9.26e-01 |
| REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION | 7 | 7.66e-01 | 0.065100 | 9.26e-01 |
| REACTOME CD28 CO STIMULATION | 32 | 7.66e-01 | 0.030400 | 9.26e-01 |
| REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | 18 | 7.66e-01 | -0.040500 | 9.26e-01 |
| REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION | 22 | 7.66e-01 | -0.036600 | 9.26e-01 |
| REACTOME SUPPRESSION OF APOPTOSIS | 7 | 7.67e-01 | 0.064800 | 9.26e-01 |
| REACTOME RAP1 SIGNALLING | 16 | 7.67e-01 | -0.042800 | 9.26e-01 |
| REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | 15 | 7.67e-01 | 0.044100 | 9.26e-01 |
| REACTOME SIGNALING BY FGFR2 IN DISEASE | 42 | 7.67e-01 | -0.026400 | 9.26e-01 |
| REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS | 5 | 7.67e-01 | 0.076400 | 9.26e-01 |
| REACTOME SARS COV 1 HOST INTERACTIONS | 92 | 7.68e-01 | 0.017800 | 9.26e-01 |
| REACTOME TNF SIGNALING | 54 | 7.68e-01 | 0.023200 | 9.26e-01 |
| REACTOME PCP CE PATHWAY | 91 | 7.68e-01 | -0.017900 | 9.26e-01 |
| REACTOME SCAVENGING BY CLASS B RECEPTORS | 6 | 7.70e-01 | 0.069100 | 9.26e-01 |
| REACTOME MRNA CAPPING | 28 | 7.70e-01 | -0.032000 | 9.26e-01 |
| REACTOME SIGNALING BY FGFR IN DISEASE | 62 | 7.70e-01 | 0.021500 | 9.26e-01 |
| REACTOME FRS MEDIATED FGFR3 SIGNALING | 19 | 7.73e-01 | -0.038300 | 9.28e-01 |
| REACTOME DEFECTIVE CHST6 CAUSES MCDC1 | 8 | 7.73e-01 | -0.058900 | 9.28e-01 |
| REACTOME ABC TRANSPORTER DISORDERS | 76 | 7.73e-01 | 0.019100 | 9.28e-01 |
| REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY | 54 | 7.74e-01 | -0.022600 | 9.28e-01 |
| REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | 62 | 7.74e-01 | 0.021100 | 9.28e-01 |
| REACTOME FORMATION OF APOPTOSOME | 10 | 7.76e-01 | -0.051900 | 9.29e-01 |
| REACTOME CYTOPROTECTION BY HMOX1 | 59 | 7.77e-01 | -0.021400 | 9.29e-01 |
| REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING | 33 | 7.78e-01 | 0.028400 | 9.29e-01 |
| REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | 16 | 7.78e-01 | -0.040800 | 9.29e-01 |
| REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN | 5 | 7.78e-01 | -0.072800 | 9.29e-01 |
| REACTOME ELASTIC FIBRE FORMATION | 44 | 7.80e-01 | 0.024300 | 9.31e-01 |
| REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR | 7 | 7.80e-01 | 0.060800 | 9.31e-01 |
| REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES | 118 | 7.84e-01 | -0.014600 | 9.33e-01 |
| REACTOME METABOLISM OF FOLATE AND PTERINES | 17 | 7.84e-01 | 0.038300 | 9.33e-01 |
| REACTOME TRANSLATION | 278 | 7.85e-01 | -0.009500 | 9.33e-01 |
| REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING | 5 | 7.85e-01 | 0.070400 | 9.33e-01 |
| REACTOME PINK1 PRKN MEDIATED MITOPHAGY | 22 | 7.86e-01 | 0.033500 | 9.33e-01 |
| REACTOME SULFUR AMINO ACID METABOLISM | 27 | 7.87e-01 | -0.030000 | 9.35e-01 |
| REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 | 7 | 7.89e-01 | -0.058500 | 9.35e-01 |
| REACTOME NICOTINAMIDE SALVAGING | 19 | 7.89e-01 | -0.035500 | 9.35e-01 |
| REACTOME METABOLISM OF VITAMINS AND COFACTORS | 185 | 7.90e-01 | 0.011400 | 9.36e-01 |
| REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE | 5 | 7.92e-01 | -0.068000 | 9.36e-01 |
| REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | 118 | 7.92e-01 | 0.014000 | 9.36e-01 |
| REACTOME RHOBTB3 ATPASE CYCLE | 8 | 7.92e-01 | 0.053700 | 9.36e-01 |
| REACTOME CHL1 INTERACTIONS | 9 | 7.93e-01 | -0.050600 | 9.36e-01 |
| REACTOME NGF STIMULATED TRANSCRIPTION | 38 | 7.96e-01 | -0.024200 | 9.36e-01 |
| REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING | 103 | 7.96e-01 | 0.014700 | 9.36e-01 |
| REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | 17 | 7.96e-01 | 0.036200 | 9.36e-01 |
| REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | 34 | 7.96e-01 | -0.025600 | 9.36e-01 |
| REACTOME IRS ACTIVATION | 5 | 7.97e-01 | 0.066400 | 9.36e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST | 14 | 7.99e-01 | 0.039300 | 9.36e-01 |
| REACTOME TOLL LIKE RECEPTOR CASCADES | 158 | 7.99e-01 | 0.011700 | 9.36e-01 |
| REACTOME RHO GTPASES ACTIVATE ROCKS | 19 | 8.00e-01 | 0.033600 | 9.36e-01 |
| REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS | 100 | 8.01e-01 | -0.014600 | 9.36e-01 |
| REACTOME RAC1 GTPASE CYCLE | 172 | 8.01e-01 | 0.011100 | 9.36e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING | 25 | 8.01e-01 | 0.029100 | 9.36e-01 |
| REACTOME ERKS ARE INACTIVATED | 13 | 8.02e-01 | -0.040300 | 9.36e-01 |
| REACTOME VASOPRESSIN LIKE RECEPTORS | 5 | 8.02e-01 | 0.064800 | 9.36e-01 |
| REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI | 5 | 8.02e-01 | -0.064700 | 9.36e-01 |
| REACTOME RSK ACTIVATION | 5 | 8.02e-01 | -0.064700 | 9.36e-01 |
| REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | 30 | 8.03e-01 | -0.026300 | 9.36e-01 |
| REACTOME L1CAM INTERACTIONS | 112 | 8.03e-01 | 0.013700 | 9.36e-01 |
| REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS | 418 | 8.04e-01 | -0.007060 | 9.36e-01 |
| REACTOME RAB GERANYLGERANYLATION | 57 | 8.05e-01 | -0.018900 | 9.36e-01 |
| REACTOME MAPK1 ERK2 ACTIVATION | 9 | 8.05e-01 | -0.047500 | 9.36e-01 |
| REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 | 8 | 8.05e-01 | 0.050300 | 9.36e-01 |
| REACTOME DEFENSINS | 33 | 8.05e-01 | 0.024800 | 9.36e-01 |
| REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING | 145 | 8.06e-01 | -0.011800 | 9.36e-01 |
| REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX | 15 | 8.07e-01 | 0.036400 | 9.37e-01 |
| REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS | 188 | 8.09e-01 | -0.010200 | 9.39e-01 |
| REACTOME ESTROGEN BIOSYNTHESIS | 6 | 8.11e-01 | -0.056400 | 9.39e-01 |
| REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 8.11e-01 | 0.038200 | 9.39e-01 |
| REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 | 8 | 8.12e-01 | -0.048600 | 9.39e-01 |
| REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA | 9 | 8.12e-01 | -0.045900 | 9.39e-01 |
| REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 | 59 | 8.12e-01 | 0.017900 | 9.39e-01 |
| REACTOME HSF1 ACTIVATION | 29 | 8.13e-01 | -0.025300 | 9.40e-01 |
| REACTOME PHENYLALANINE METABOLISM | 6 | 8.16e-01 | 0.055000 | 9.41e-01 |
| REACTOME FRUCTOSE METABOLISM | 7 | 8.16e-01 | -0.050900 | 9.41e-01 |
| REACTOME MIRO GTPASE CYCLE | 8 | 8.16e-01 | 0.047500 | 9.41e-01 |
| REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION | 6 | 8.19e-01 | 0.054000 | 9.43e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | 14 | 8.20e-01 | -0.035200 | 9.44e-01 |
| REACTOME CELLULAR RESPONSE TO STARVATION | 147 | 8.20e-01 | 0.010900 | 9.44e-01 |
| REACTOME SODIUM PROTON EXCHANGERS | 7 | 8.22e-01 | 0.049100 | 9.44e-01 |
| REACTOME MINERALOCORTICOID BIOSYNTHESIS | 6 | 8.22e-01 | 0.053000 | 9.44e-01 |
| REACTOME REGULATION OF NF KAPPA B SIGNALING | 17 | 8.22e-01 | -0.031500 | 9.44e-01 |
| REACTOME NEUROFASCIN INTERACTIONS | 6 | 8.23e-01 | 0.052800 | 9.44e-01 |
| REACTOME ENOS ACTIVATION | 11 | 8.24e-01 | -0.038800 | 9.44e-01 |
| REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | 20 | 8.24e-01 | -0.028700 | 9.44e-01 |
| REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING | 23 | 8.25e-01 | -0.026700 | 9.44e-01 |
| REACTOME KERATAN SULFATE KERATIN METABOLISM | 34 | 8.26e-01 | 0.021800 | 9.45e-01 |
| REACTOME P75NTR SIGNALS VIA NF KB | 15 | 8.27e-01 | -0.032700 | 9.45e-01 |
| REACTOME SIGNALING BY HIPPO | 19 | 8.29e-01 | 0.028600 | 9.47e-01 |
| REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS | 9 | 8.30e-01 | 0.041200 | 9.47e-01 |
| REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 5 | 8.31e-01 | 0.055200 | 9.47e-01 |
| REACTOME NICOTINATE METABOLISM | 31 | 8.31e-01 | -0.022100 | 9.47e-01 |
| REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION | 37 | 8.32e-01 | 0.020200 | 9.47e-01 |
| REACTOME NECTIN NECL TRANS HETERODIMERIZATION | 7 | 8.32e-01 | 0.046200 | 9.47e-01 |
| REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | 15 | 8.32e-01 | -0.031600 | 9.47e-01 |
| REACTOME FOLDING OF ACTIN BY CCT TRIC | 10 | 8.33e-01 | -0.038500 | 9.47e-01 |
| REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES | 9 | 8.34e-01 | -0.040300 | 9.48e-01 |
| REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT | 19 | 8.37e-01 | 0.027200 | 9.50e-01 |
| REACTOME SIGNALING BY NODAL | 20 | 8.38e-01 | 0.026400 | 9.50e-01 |
| REACTOME INTERFERON SIGNALING | 193 | 8.38e-01 | -0.008520 | 9.50e-01 |
| REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY | 8 | 8.39e-01 | 0.041600 | 9.50e-01 |
| REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS | 10 | 8.39e-01 | 0.037000 | 9.50e-01 |
| REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE | 17 | 8.40e-01 | 0.028300 | 9.50e-01 |
| REACTOME IRAK1 RECRUITS IKK COMPLEX | 12 | 8.40e-01 | -0.033600 | 9.50e-01 |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 20 | 8.43e-01 | 0.025600 | 9.51e-01 |
| REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS | 161 | 8.43e-01 | 0.009050 | 9.51e-01 |
| REACTOME METABOLISM OF POLYAMINES | 56 | 8.44e-01 | -0.015200 | 9.51e-01 |
| REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION | 23 | 8.44e-01 | -0.023700 | 9.51e-01 |
| REACTOME TRANSLESION SYNTHESIS BY POLK | 17 | 8.45e-01 | -0.027500 | 9.51e-01 |
| REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | 76 | 8.45e-01 | -0.013000 | 9.51e-01 |
| REACTOME DEFECTIVE CHST3 CAUSES SEDCJD | 7 | 8.45e-01 | 0.042600 | 9.51e-01 |
| REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS | 12 | 8.46e-01 | -0.032500 | 9.51e-01 |
| REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION | 6 | 8.47e-01 | -0.045500 | 9.51e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 | 17 | 8.48e-01 | -0.026900 | 9.51e-01 |
| REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY | 30 | 8.48e-01 | -0.020200 | 9.51e-01 |
| REACTOME CS DS DEGRADATION | 12 | 8.49e-01 | -0.031800 | 9.51e-01 |
| REACTOME ERYTHROPOIETIN ACTIVATES RAS | 14 | 8.49e-01 | 0.029400 | 9.51e-01 |
| REACTOME REGULATED PROTEOLYSIS OF P75NTR | 11 | 8.49e-01 | -0.033100 | 9.51e-01 |
| REACTOME MRNA EDITING C TO U CONVERSION | 8 | 8.50e-01 | 0.038600 | 9.51e-01 |
| REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 | 46 | 8.52e-01 | 0.015900 | 9.52e-01 |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 8.52e-01 | 0.022900 | 9.52e-01 |
| REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION | 7 | 8.53e-01 | -0.040400 | 9.52e-01 |
| REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 53 | 8.54e-01 | -0.014600 | 9.52e-01 |
| REACTOME PRE NOTCH PROCESSING IN GOLGI | 18 | 8.55e-01 | -0.025000 | 9.52e-01 |
| REACTOME GDP FUCOSE BIOSYNTHESIS | 6 | 8.55e-01 | -0.043100 | 9.52e-01 |
| REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL | 12 | 8.55e-01 | 0.030400 | 9.52e-01 |
| REACTOME INTERLEUKIN 1 PROCESSING | 9 | 8.56e-01 | 0.035000 | 9.52e-01 |
| REACTOME SYNTHESIS OF PA | 38 | 8.56e-01 | -0.017000 | 9.52e-01 |
| REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R | 52 | 8.57e-01 | -0.014500 | 9.52e-01 |
| REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE | 15 | 8.57e-01 | -0.026900 | 9.52e-01 |
| REACTOME INTERLEUKIN 6 SIGNALING | 11 | 8.57e-01 | -0.031300 | 9.52e-01 |
| REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA | 15 | 8.59e-01 | 0.026600 | 9.52e-01 |
| REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA | 17 | 8.59e-01 | -0.024900 | 9.52e-01 |
| REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX | 5 | 8.61e-01 | -0.045300 | 9.54e-01 |
| REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION | 7 | 8.61e-01 | 0.038100 | 9.54e-01 |
| REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES | 16 | 8.65e-01 | 0.024600 | 9.57e-01 |
| REACTOME PI 3K CASCADE FGFR4 | 19 | 8.67e-01 | 0.022100 | 9.59e-01 |
| REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE | 9 | 8.69e-01 | 0.031800 | 9.59e-01 |
| REACTOME HIV ELONGATION ARREST AND RECOVERY | 33 | 8.69e-01 | 0.016600 | 9.59e-01 |
| REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | 26 | 8.69e-01 | -0.018700 | 9.59e-01 |
| REACTOME FORMATION OF TC NER PRE INCISION COMPLEX | 51 | 8.71e-01 | 0.013200 | 9.60e-01 |
| REACTOME PYRIMIDINE CATABOLISM | 12 | 8.71e-01 | 0.027000 | 9.60e-01 |
| REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE | 20 | 8.71e-01 | -0.020900 | 9.60e-01 |
| REACTOME TRAF6 MEDIATED NF KB ACTIVATION | 24 | 8.76e-01 | 0.018500 | 9.64e-01 |
| REACTOME UNFOLDED PROTEIN RESPONSE UPR | 88 | 8.78e-01 | 0.009490 | 9.65e-01 |
| REACTOME MITOPHAGY | 28 | 8.78e-01 | -0.016700 | 9.65e-01 |
| REACTOME HEDGEHOG LIGAND BIOGENESIS | 64 | 8.80e-01 | -0.011000 | 9.65e-01 |
| REACTOME ACYL CHAIN REMODELING OF CL | 5 | 8.81e-01 | -0.038800 | 9.65e-01 |
| REACTOME METABOLISM OF CARBOHYDRATES | 279 | 8.81e-01 | 0.005220 | 9.65e-01 |
| REACTOME INFLUENZA INFECTION | 149 | 8.81e-01 | 0.007110 | 9.65e-01 |
| REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES | 8 | 8.81e-01 | 0.030500 | 9.65e-01 |
| REACTOME DISEASES OF MISMATCH REPAIR MMR | 5 | 8.83e-01 | 0.038100 | 9.65e-01 |
| REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE | 7 | 8.83e-01 | -0.032100 | 9.65e-01 |
| REACTOME FRS MEDIATED FGFR1 SIGNALING | 23 | 8.83e-01 | -0.017700 | 9.65e-01 |
| REACTOME OVARIAN TUMOR DOMAIN PROTEASES | 36 | 8.83e-01 | 0.014100 | 9.65e-01 |
| REACTOME RHOA GTPASE CYCLE | 142 | 8.84e-01 | -0.007070 | 9.65e-01 |
| REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION | 19 | 8.85e-01 | 0.019200 | 9.65e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 | 26 | 8.89e-01 | 0.015800 | 9.70e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS | 34 | 8.91e-01 | -0.013600 | 9.70e-01 |
| REACTOME GLUCURONIDATION | 23 | 8.91e-01 | -0.016500 | 9.70e-01 |
| REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 | 11 | 8.91e-01 | -0.023800 | 9.70e-01 |
| REACTOME SIGNALING BY RNF43 MUTANTS | 8 | 8.93e-01 | -0.027600 | 9.70e-01 |
| REACTOME LIPID PARTICLE ORGANIZATION | 6 | 8.93e-01 | -0.031700 | 9.70e-01 |
| REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT | 6 | 8.94e-01 | -0.031500 | 9.70e-01 |
| REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS | 21 | 8.94e-01 | 0.016700 | 9.70e-01 |
| REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX | 21 | 8.95e-01 | 0.016700 | 9.70e-01 |
| REACTOME FRUCTOSE CATABOLISM | 5 | 8.96e-01 | -0.033900 | 9.70e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR3 | 17 | 8.96e-01 | -0.018400 | 9.70e-01 |
| REACTOME RELAXIN RECEPTORS | 8 | 8.96e-01 | -0.026700 | 9.70e-01 |
| REACTOME SIGNALING BY NOTCH1 | 69 | 8.96e-01 | -0.009070 | 9.70e-01 |
| REACTOME SIGNALING BY RETINOIC ACID | 41 | 8.98e-01 | -0.011600 | 9.70e-01 |
| REACTOME PERK REGULATES GENE EXPRESSION | 31 | 8.98e-01 | -0.013300 | 9.70e-01 |
| REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 | 9 | 8.99e-01 | 0.024300 | 9.70e-01 |
| REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION | 30 | 9.00e-01 | -0.013300 | 9.70e-01 |
| REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS | 7 | 9.00e-01 | 0.027400 | 9.70e-01 |
| REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | 89 | 9.01e-01 | -0.007650 | 9.70e-01 |
| REACTOME SIGNALING BY INSULIN RECEPTOR | 80 | 9.03e-01 | -0.007900 | 9.72e-01 |
| REACTOME ACTIVATION OF RAS IN B CELLS | 5 | 9.05e-01 | -0.030900 | 9.73e-01 |
| REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 16 | 9.05e-01 | -0.017200 | 9.73e-01 |
| REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 | 14 | 9.05e-01 | 0.018400 | 9.73e-01 |
| REACTOME MYOGENESIS | 29 | 9.06e-01 | 0.012700 | 9.73e-01 |
| REACTOME IRON UPTAKE AND TRANSPORT | 56 | 9.07e-01 | -0.009030 | 9.73e-01 |
| REACTOME THE ACTIVATION OF ARYLSULFATASES | 8 | 9.08e-01 | -0.023600 | 9.73e-01 |
| REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES | 17 | 9.08e-01 | -0.016200 | 9.73e-01 |
| REACTOME NEGATIVE REGULATION OF MAPK PATHWAY | 41 | 9.09e-01 | -0.010300 | 9.74e-01 |
| REACTOME NEUROTRANSMITTER CLEARANCE | 9 | 9.10e-01 | 0.021800 | 9.74e-01 |
| REACTOME INTERLEUKIN 1 FAMILY SIGNALING | 146 | 9.11e-01 | 0.005340 | 9.74e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE | 8 | 9.12e-01 | 0.022600 | 9.74e-01 |
| REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING | 61 | 9.12e-01 | -0.008190 | 9.74e-01 |
| REACTOME NADE MODULATES DEATH SIGNALLING | 5 | 9.13e-01 | -0.028200 | 9.74e-01 |
| REACTOME DEATH RECEPTOR SIGNALING | 143 | 9.13e-01 | 0.005280 | 9.74e-01 |
| REACTOME PI 3K CASCADE FGFR2 | 22 | 9.14e-01 | -0.013400 | 9.74e-01 |
| REACTOME MUCOPOLYSACCHARIDOSES | 10 | 9.14e-01 | -0.019800 | 9.74e-01 |
| REACTOME FGFR1C LIGAND BINDING AND ACTIVATION | 11 | 9.15e-01 | -0.018600 | 9.74e-01 |
| REACTOME HIV TRANSCRIPTION ELONGATION | 42 | 9.16e-01 | 0.009440 | 9.74e-01 |
| REACTOME VLDL ASSEMBLY | 5 | 9.17e-01 | -0.026900 | 9.74e-01 |
| REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | 10 | 9.19e-01 | -0.018700 | 9.74e-01 |
| REACTOME NUCLEOTIDE BIOSYNTHESIS | 14 | 9.19e-01 | -0.015600 | 9.74e-01 |
| REACTOME SIGNALING BY VEGF | 102 | 9.20e-01 | 0.005760 | 9.74e-01 |
| REACTOME PTK6 EXPRESSION | 5 | 9.20e-01 | 0.025800 | 9.74e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR4 | 19 | 9.20e-01 | 0.013200 | 9.74e-01 |
| REACTOME REDUCTION OF CYTOSOLIC CA LEVELS | 11 | 9.21e-01 | -0.017200 | 9.74e-01 |
| REACTOME GLUCOSE METABOLISM | 90 | 9.21e-01 | 0.006020 | 9.74e-01 |
| REACTOME HYALURONAN UPTAKE AND DEGRADATION | 12 | 9.22e-01 | -0.016400 | 9.74e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 | 29 | 9.22e-01 | -0.010500 | 9.74e-01 |
| REACTOME REGULATION OF SIGNALING BY NODAL | 9 | 9.22e-01 | -0.018800 | 9.74e-01 |
| REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION | 8 | 9.25e-01 | -0.019200 | 9.76e-01 |
| REACTOME RHOB GTPASE CYCLE | 67 | 9.25e-01 | -0.006620 | 9.76e-01 |
| REACTOME DISEASES OF CARBOHYDRATE METABOLISM | 31 | 9.25e-01 | -0.009720 | 9.76e-01 |
| REACTOME KERATAN SULFATE DEGRADATION | 13 | 9.26e-01 | -0.014900 | 9.76e-01 |
| REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION | 15 | 9.27e-01 | -0.013600 | 9.76e-01 |
| REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | 12 | 9.28e-01 | 0.015000 | 9.76e-01 |
| REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR | 8 | 9.28e-01 | -0.018400 | 9.76e-01 |
| REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA | 7 | 9.28e-01 | 0.019600 | 9.76e-01 |
| REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS | 12 | 9.29e-01 | -0.014800 | 9.76e-01 |
| REACTOME SIGNALING BY LRP5 MUTANTS | 6 | 9.30e-01 | 0.020700 | 9.76e-01 |
| REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE | 7 | 9.30e-01 | -0.019200 | 9.76e-01 |
| REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX | 9 | 9.32e-01 | 0.016500 | 9.77e-01 |
| REACTOME INTERLEUKIN 17 SIGNALING | 66 | 9.33e-01 | 0.006010 | 9.77e-01 |
| REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ | 6 | 9.34e-01 | -0.019600 | 9.78e-01 |
| REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS | 11 | 9.34e-01 | 0.014300 | 9.78e-01 |
| REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | 54 | 9.36e-01 | 0.006290 | 9.78e-01 |
| REACTOME WNT MEDIATED ACTIVATION OF DVL | 8 | 9.36e-01 | -0.016300 | 9.78e-01 |
| REACTOME PROTEIN LOCALIZATION | 153 | 9.37e-01 | 0.003720 | 9.78e-01 |
| REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES | 16 | 9.38e-01 | 0.011300 | 9.79e-01 |
| REACTOME SIGNALING BY FLT3 FUSION PROTEINS | 19 | 9.39e-01 | -0.010200 | 9.79e-01 |
| REACTOME ARACHIDONATE PRODUCTION FROM DAG | 5 | 9.42e-01 | 0.018900 | 9.82e-01 |
| REACTOME DAP12 SIGNALING | 27 | 9.44e-01 | -0.007850 | 9.83e-01 |
| REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS | 14 | 9.44e-01 | 0.010800 | 9.83e-01 |
| REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | 45 | 9.44e-01 | 0.006010 | 9.83e-01 |
| REACTOME SOS MEDIATED SIGNALLING | 7 | 9.46e-01 | -0.014800 | 9.84e-01 |
| REACTOME PI 3K CASCADE FGFR1 | 21 | 9.46e-01 | 0.008470 | 9.84e-01 |
| REACTOME PLASMA LIPOPROTEIN ASSEMBLY | 19 | 9.48e-01 | 0.008610 | 9.84e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 | 6 | 9.48e-01 | 0.015300 | 9.84e-01 |
| REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | 11 | 9.50e-01 | 0.011000 | 9.84e-01 |
| REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX | 10 | 9.50e-01 | -0.011400 | 9.84e-01 |
| REACTOME FRS MEDIATED FGFR4 SIGNALING | 21 | 9.51e-01 | -0.007810 | 9.84e-01 |
| REACTOME PI 3K CASCADE FGFR3 | 17 | 9.52e-01 | -0.008410 | 9.84e-01 |
| REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | 24 | 9.53e-01 | 0.007010 | 9.84e-01 |
| REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL | 19 | 9.54e-01 | -0.007700 | 9.84e-01 |
| REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | 14 | 9.54e-01 | -0.008830 | 9.84e-01 |
| REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES | 14 | 9.55e-01 | -0.008780 | 9.84e-01 |
| REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY | 5 | 9.55e-01 | -0.014700 | 9.84e-01 |
| REACTOME KILLING MECHANISMS | 11 | 9.55e-01 | 0.009820 | 9.84e-01 |
| REACTOME MYOCLONIC EPILEPSY OF LAFORA | 9 | 9.56e-01 | -0.010700 | 9.84e-01 |
| REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND | 16 | 9.56e-01 | -0.007920 | 9.84e-01 |
| REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE | 9 | 9.56e-01 | -0.010500 | 9.84e-01 |
| REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 | 24 | 9.57e-01 | -0.006400 | 9.84e-01 |
| REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 | 20 | 9.57e-01 | -0.006890 | 9.84e-01 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES | 11 | 9.58e-01 | -0.009140 | 9.84e-01 |
| REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS | 5 | 9.58e-01 | 0.013500 | 9.84e-01 |
| REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 | 33 | 9.60e-01 | -0.005090 | 9.84e-01 |
| REACTOME SIGNALING BY FGFR | 85 | 9.60e-01 | 0.003170 | 9.84e-01 |
| REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION | 27 | 9.60e-01 | -0.005560 | 9.84e-01 |
| REACTOME FORMATION OF INCISION COMPLEX IN GG NER | 40 | 9.61e-01 | -0.004480 | 9.84e-01 |
| REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE | 11 | 9.65e-01 | -0.007670 | 9.88e-01 |
| REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER | 54 | 9.65e-01 | 0.003400 | 9.88e-01 |
| REACTOME SIGNALING BY ROBO RECEPTORS | 206 | 9.67e-01 | 0.001670 | 9.88e-01 |
| REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE | 20 | 9.67e-01 | -0.005320 | 9.88e-01 |
| REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE | 7 | 9.68e-01 | 0.008820 | 9.88e-01 |
| REACTOME ENDOSOMAL VACUOLAR PATHWAY | 11 | 9.70e-01 | 0.006460 | 9.89e-01 |
| REACTOME DAP12 INTERACTIONS | 37 | 9.70e-01 | -0.003530 | 9.89e-01 |
| REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS | 27 | 9.71e-01 | 0.004010 | 9.89e-01 |
| REACTOME VLDL CLEARANCE | 6 | 9.71e-01 | 0.008470 | 9.89e-01 |
| REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING | 53 | 9.73e-01 | 0.002680 | 9.91e-01 |
| REACTOME ADRENOCEPTORS | 9 | 9.75e-01 | 0.006040 | 9.91e-01 |
| REACTOME RHO GTPASES ACTIVATE PAKS | 19 | 9.76e-01 | 0.003940 | 9.91e-01 |
| REACTOME CDC42 GTPASE CYCLE | 144 | 9.77e-01 | -0.001380 | 9.91e-01 |
| REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | 13 | 9.78e-01 | -0.004490 | 9.91e-01 |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 729 | 9.79e-01 | 0.000585 | 9.91e-01 |
| REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES | 10 | 9.79e-01 | -0.004880 | 9.91e-01 |
| REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 255 | 9.79e-01 | -0.000960 | 9.91e-01 |
| REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION | 15 | 9.80e-01 | -0.003830 | 9.91e-01 |
| REACTOME DEFECTIVE LFNG CAUSES SCDO3 | 5 | 9.80e-01 | -0.006620 | 9.91e-01 |
| REACTOME LATE SARS COV 2 INFECTION EVENTS | 67 | 9.80e-01 | -0.001810 | 9.91e-01 |
| REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | 24 | 9.80e-01 | -0.002980 | 9.91e-01 |
| REACTOME TACHYKININ RECEPTORS BIND TACHYKININS | 5 | 9.81e-01 | -0.006200 | 9.91e-01 |
| REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA | 17 | 9.81e-01 | -0.003310 | 9.91e-01 |
| REACTOME EICOSANOID LIGAND BINDING RECEPTORS | 14 | 9.83e-01 | 0.003360 | 9.91e-01 |
| REACTOME RAF ACTIVATION | 33 | 9.83e-01 | -0.002150 | 9.91e-01 |
| REACTOME RUNX3 REGULATES NOTCH SIGNALING | 13 | 9.85e-01 | -0.002980 | 9.92e-01 |
| REACTOME PROLONGED ERK ACTIVATION EVENTS | 14 | 9.86e-01 | -0.002780 | 9.92e-01 |
| REACTOME SIGNALING BY FGFR2 IIIA TM | 19 | 9.86e-01 | 0.002360 | 9.92e-01 |
| REACTOME BETA DEFENSINS | 27 | 9.91e-01 | -0.001280 | 9.96e-01 |
| REACTOME OAS ANTIVIRAL RESPONSE | 8 | 9.92e-01 | -0.002160 | 9.96e-01 |
| REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE | 7 | 9.92e-01 | -0.002290 | 9.96e-01 |
| REACTOME FATTY ACYL COA BIOSYNTHESIS | 36 | 9.92e-01 | 0.000915 | 9.97e-01 |
| REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS | 6 | 9.93e-01 | -0.002090 | 9.97e-01 |
| REACTOME MISMATCH REPAIR | 15 | 9.95e-01 | -0.000946 | 9.98e-01 |
| REACTOME SHC MEDIATED CASCADE FGFR1 | 21 | 9.97e-01 | 0.000412 | 9.99e-01 |
| REACTOME PEPTIDE HORMONE METABOLISM | 84 | 9.97e-01 | -0.000199 | 9.99e-01 |
| REACTOME SYNTHESIS OF GDP MANNOSE | 5 | 9.98e-01 | -0.000491 | 9.99e-01 |
| REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN | 7 | 9.99e-01 | 0.000390 | 9.99e-01 |
| REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | 12 | 9.99e-01 | 0.000182 | 9.99e-01 |
Detailed Gene set reports
REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
| 1161 | |
|---|---|
| set | REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION |
| setSize | 1336 |
| pANOVA | 1.61e-19 |
| s.dist | -0.147 |
| p.adjustANOVA | 2.65e-16 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CGB5 | -10398 |
| ZNF587 | -10257 |
| ZNF431 | -10158 |
| ZNF701 | -10107 |
| TWIST2 | -10089 |
| ZNF492 | -10042 |
| POU4F2 | -9999 |
| ZNF417 | -9991 |
| ZNF439 | -9978 |
| FOXG1 | -9972 |
| ZNF699 | -9926 |
| CLDN5 | -9895 |
| ZIM2 | -9890 |
| MSX2 | -9862 |
| MAF | -9851 |
| SOX2 | -9831 |
| EIF4A3 | -9788 |
| ZNF331 | -9769 |
| ZNF468 | -9765 |
| ITGAL | -9733 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CGB5 | -10398.0 |
| ZNF587 | -10257.0 |
| ZNF431 | -10158.0 |
| ZNF701 | -10107.0 |
| TWIST2 | -10089.0 |
| ZNF492 | -10042.0 |
| POU4F2 | -9999.0 |
| ZNF417 | -9991.0 |
| ZNF439 | -9978.0 |
| FOXG1 | -9972.0 |
| ZNF699 | -9926.0 |
| CLDN5 | -9895.0 |
| ZIM2 | -9890.0 |
| MSX2 | -9862.0 |
| MAF | -9851.0 |
| SOX2 | -9831.0 |
| EIF4A3 | -9788.0 |
| ZNF331 | -9769.0 |
| ZNF468 | -9765.0 |
| ITGAL | -9733.0 |
| ZNF74 | -9731.0 |
| ZNF732 | -9720.0 |
| SERPINE1 | -9678.0 |
| DLX6 | -9649.0 |
| ZKSCAN7 | -9640.0 |
| ZNF253 | -9628.0 |
| CNOT6 | -9599.0 |
| BMP2 | -9575.0 |
| HAND2 | -9569.0 |
| DDX39B | -9566.0 |
| YY1 | -9556.0 |
| CHEK1 | -9546.0 |
| ZNF726 | -9539.0 |
| NR2C2AP | -9524.0 |
| ZNF703 | -9520.0 |
| ZNF506 | -9496.0 |
| UBE2C | -9474.0 |
| JUNB | -9467.0 |
| ZFP28 | -9466.0 |
| H3C12 | -9458.0 |
| NKX2-5 | -9457.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| ZNF678 | -9387.0 |
| ZNF875 | -9365.0 |
| TFAP2C | -9348.0 |
| PHC1 | -9332.0 |
| HDAC1 | -9320.0 |
| ZNF658 | -9315.0 |
| NR4A3 | -9308.0 |
| AIFM2 | -9297.0 |
| TFAP2A | -9292.0 |
| ZNF493 | -9288.0 |
| ZNF28 | -9275.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| ZNF155 | -9228.0 |
| ZNF662 | -9209.0 |
| GATA3 | -9199.0 |
| TWIST1 | -9187.0 |
| ZNF860 | -9176.0 |
| PITX2 | -9170.0 |
| ZNF19 | -9168.0 |
| CYCS | -9162.0 |
| ZNF135 | -9145.0 |
| COX6C | -9132.0 |
| ZNF595 | -9126.0 |
| ZNF445 | -9123.0 |
| TFDP1 | -9109.0 |
| KLF4 | -9103.0 |
| ZNF3 | -9101.0 |
| CGB8 | -9069.0 |
| NR2F1 | -9063.0 |
| ZNF23 | -9054.0 |
| ZNF568 | -9053.0 |
| ZNF671 | -9052.0 |
| RICTOR | -8995.0 |
| EAF1 | -8994.0 |
| ZNF285 | -8987.0 |
| PHF20 | -8977.0 |
| CCNB1 | -8935.0 |
| SNAPC4 | -8933.0 |
| ZNF750 | -8911.0 |
| PSMD2 | -8887.0 |
| INTS5 | -8885.0 |
| ZNF682 | -8862.0 |
| IGFBP1 | -8861.0 |
| TFAP2E | -8859.0 |
| ZNF100 | -8858.0 |
| ZNF773 | -8857.0 |
| RHNO1 | -8854.0 |
| ZNF471 | -8853.0 |
| ZNF735 | -8847.0 |
| CCNG2 | -8815.0 |
| KMT2A | -8808.0 |
| ZNF184 | -8800.0 |
| ZNF75A | -8796.0 |
| GAD1 | -8784.0 |
| ZSCAN25 | -8767.0 |
| ZNF772 | -8762.0 |
| ZNF425 | -8757.0 |
| ZNF26 | -8741.0 |
| ZNF621 | -8728.0 |
| SYT10 | -8720.0 |
| RB1 | -8714.0 |
| POU4F1 | -8697.0 |
| TRIM33 | -8695.0 |
| ZNF586 | -8694.0 |
| SUZ12 | -8683.0 |
| ANAPC5 | -8661.0 |
| CASP10 | -8659.0 |
| ZNF200 | -8647.0 |
| ZKSCAN5 | -8627.0 |
| DHX38 | -8620.0 |
| ZNF519 | -8619.0 |
| NKX3-2 | -8610.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| THBS1 | -8580.0 |
| ZC3H8 | -8557.0 |
| NR2E1 | -8545.0 |
| ZNF737 | -8544.0 |
| GPAM | -8535.0 |
| ZNF230 | -8529.0 |
| GPX2 | -8521.0 |
| CTSL | -8517.0 |
| KAT6A | -8514.0 |
| PSMB11 | -8512.0 |
| ERBB2 | -8501.0 |
| ZNF681 | -8485.0 |
| IGFBP3 | -8484.0 |
| SNAPC2 | -8481.0 |
| ZNF233 | -8476.0 |
| CPSF2 | -8474.0 |
| PABPN1 | -8466.0 |
| BRD7 | -8445.0 |
| ZNF354A | -8438.0 |
| ZNF257 | -8412.0 |
| NELFA | -8408.0 |
| ZNF549 | -8406.0 |
| BRPF3 | -8405.0 |
| MIR24-1 | -8393.0 |
| ZSCAN32 | -8357.0 |
| ZNF749 | -8355.0 |
| ZNF577 | -8348.0 |
| CNOT6L | -8328.0 |
| MED8 | -8323.0 |
| ZNF124 | -8319.0 |
| NR4A2 | -8311.0 |
| TRIAP1 | -8304.0 |
| TXN | -8297.0 |
| CTDP1 | -8294.0 |
| TMEM219 | -8223.0 |
| SLU7 | -8211.0 |
| H2BC13 | -8199.0 |
| GTF2E2 | -8198.0 |
| ZNF627 | -8188.0 |
| ZNF248 | -8183.0 |
| ZNF670 | -8181.0 |
| ZNF43 | -8177.0 |
| IL6 | -8175.0 |
| CASP6 | -8122.0 |
| ZNF2 | -8119.0 |
| MTOR | -8114.0 |
| H4C16 | -8109.0 |
| CNOT1 | -8093.0 |
| ZNF551 | -8071.0 |
| ASH2L | -8064.0 |
| ZNF605 | -8056.0 |
| ZNF12 | -8029.0 |
| PPARA | -8024.0 |
| YWHAB | -8002.0 |
| TNFRSF10C | -7986.0 |
| ZNF112 | -7982.0 |
| KMT2C | -7976.0 |
| RBM8A | -7974.0 |
| INTS2 | -7973.0 |
| ZNF420 | -7965.0 |
| ZNF738 | -7927.0 |
| MED16 | -7906.0 |
| NR3C2 | -7900.0 |
| CASP2 | -7894.0 |
| ZNF484 | -7891.0 |
| SIN3B | -7854.0 |
| PSMC1 | -7848.0 |
| MAPKAPK5 | -7833.0 |
| ANAPC4 | -7831.0 |
| ZNF350 | -7830.0 |
| ZNF707 | -7827.0 |
| DGCR8 | -7822.0 |
| H2BC5 | -7799.0 |
| ZNF718 | -7765.0 |
| ZNF180 | -7756.0 |
| RPA1 | -7755.0 |
| HDAC2 | -7742.0 |
| COL1A2 | -7719.0 |
| CNOT9 | -7665.0 |
| H2AX | -7648.0 |
| RNF111 | -7646.0 |
| SMAD2 | -7644.0 |
| ZNF77 | -7640.0 |
| SRSF9 | -7628.0 |
| ZNF667 | -7623.0 |
| BRPF1 | -7613.0 |
| KRBA1 | -7606.0 |
| ZNF530 | -7587.0 |
| RRM2 | -7580.0 |
| ARID1B | -7557.0 |
| ZNF415 | -7549.0 |
| ATAD2 | -7541.0 |
| ZNF585B | -7529.0 |
| NOTCH2 | -7511.0 |
| ZNF714 | -7492.0 |
| PGR | -7470.0 |
| INTS9 | -7465.0 |
| TOPBP1 | -7459.0 |
| ACTL6A | -7457.0 |
| POLR2A | -7443.0 |
| RXRG | -7401.0 |
| ZNF721 | -7388.0 |
| ZNF14 | -7379.0 |
| H3C6 | -7372.0 |
| PSMD13 | -7362.0 |
| CNOT8 | -7355.0 |
| ZNF675 | -7336.0 |
| ZNF619 | -7304.0 |
| KDM5B | -7300.0 |
| SSU72 | -7273.0 |
| ZFP30 | -7252.0 |
| HDAC4 | -7226.0 |
| E2F8 | -7214.0 |
| RABGGTA | -7199.0 |
| ZNF625 | -7195.0 |
| ZNF33B | -7184.0 |
| ZNF436 | -7177.0 |
| CPSF4 | -7145.0 |
| SNRPB | -7144.0 |
| EP300 | -7126.0 |
| ZNF729 | -7107.0 |
| ZNF227 | -7102.0 |
| NCOR2 | -7068.0 |
| MED6 | -7049.0 |
| MEN1 | -7041.0 |
| ZNF268 | -7028.0 |
| CDKN1B | -6954.0 |
| NRBP1 | -6935.0 |
| ZNF317 | -6910.0 |
| HTT | -6905.0 |
| ABL1 | -6881.0 |
| PRDX2 | -6868.0 |
| TAF4 | -6859.0 |
| CDC7 | -6856.0 |
| RPRD1A | -6849.0 |
| SMARCB1 | -6836.0 |
| COX18 | -6827.0 |
| LMO2 | -6799.0 |
| ZNF724 | -6791.0 |
| COX7A2L | -6753.0 |
| TNFRSF10D | -6751.0 |
| YES1 | -6717.0 |
| ZNF263 | -6715.0 |
| CBX8 | -6701.0 |
| ZNF777 | -6698.0 |
| TOP3A | -6676.0 |
| CBX3 | -6675.0 |
| RBM14 | -6660.0 |
| NCBP1 | -6659.0 |
| ZNF264 | -6657.0 |
| ZNF610 | -6650.0 |
| SRSF2 | -6648.0 |
| FOXO3 | -6645.0 |
| PRDX1 | -6636.0 |
| INTS3 | -6611.0 |
| ZNF354C | -6609.0 |
| PSMD3 | -6608.0 |
| ZIK1 | -6599.0 |
| BMAL1 | -6531.0 |
| TCF7 | -6530.0 |
| MED1 | -6514.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| ZNF615 | -6504.0 |
| ZKSCAN1 | -6485.0 |
| BRCA1 | -6477.0 |
| NR1D1 | -6475.0 |
| PSMD9 | -6463.0 |
| TBX5 | -6451.0 |
| NR1I2 | -6423.0 |
| PSMD4 | -6409.0 |
| POLR2K | -6386.0 |
| ZNF496 | -6378.0 |
| E2F6 | -6358.0 |
| PSMB5 | -6339.0 |
| CDK8 | -6335.0 |
| GPI | -6328.0 |
| ZNF676 | -6288.0 |
| CTR9 | -6284.0 |
| WWOX | -6273.0 |
| PINK1 | -6270.0 |
| DLL1 | -6268.0 |
| NFYA | -6252.0 |
| HEY2 | -6245.0 |
| GRIA2 | -6240.0 |
| TRPC3 | -6233.0 |
| RPTOR | -6228.0 |
| GATA4 | -6202.0 |
| MOV10 | -6196.0 |
| ZNF775 | -6189.0 |
| SRRM1 | -6188.0 |
| BANP | -6187.0 |
| EHMT2 | -6169.0 |
| SURF1 | -6162.0 |
| CR1 | -6145.0 |
| ZNF30 | -6132.0 |
| VENTX | -6123.0 |
| MED30 | -6112.0 |
| CCN2 | -6105.0 |
| ZNF354B | -6102.0 |
| DLX5 | -6100.0 |
| ING5 | -6092.0 |
| ZNF514 | -6090.0 |
| CSNK2B | -6080.0 |
| ZNF570 | -6067.0 |
| TBP | -6055.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| GPRIN1 | -6002.0 |
| RNPS1 | -5988.0 |
| THOC7 | -5974.0 |
| PLK2 | -5937.0 |
| GTF2A2 | -5883.0 |
| SMURF1 | -5847.0 |
| CDK12 | -5834.0 |
| FANCC | -5831.0 |
| TAL1 | -5805.0 |
| ZNF546 | -5799.0 |
| ALYREF | -5793.0 |
| ANAPC7 | -5789.0 |
| H2AC6 | -5775.0 |
| ZNF195 | -5739.0 |
| RBBP5 | -5722.0 |
| CBX4 | -5719.0 |
| ZNF547 | -5712.0 |
| SETD1A | -5707.0 |
| WDR5 | -5702.0 |
| H2BC15 | -5694.0 |
| AKT3 | -5680.0 |
| ZNF517 | -5658.0 |
| ZNF746 | -5646.0 |
| EHMT1 | -5643.0 |
| ZNF214 | -5592.0 |
| DDIT4 | -5579.0 |
| ZNF79 | -5576.0 |
| ZNF382 | -5545.0 |
| HIPK1 | -5542.0 |
| H3C11 | -5538.0 |
| ARID1A | -5503.0 |
| CGA | -5492.0 |
| ZNF790 | -5488.0 |
| FOS | -5453.0 |
| CRH | -5434.0 |
| YWHAQ | -5428.0 |
| AKT2 | -5419.0 |
| CSTF3 | -5380.0 |
| PCF11 | -5372.0 |
| FANCI | -5363.0 |
| ZNF500 | -5331.0 |
| ZNF616 | -5326.0 |
| CBX6 | -5319.0 |
| CHTOP | -5318.0 |
| MAP2K6 | -5315.0 |
| ZNF607 | -5302.0 |
| NR3C1 | -5298.0 |
| H2BC6 | -5295.0 |
| TFAP2D | -5279.0 |
| SLC38A9 | -5278.0 |
| INTS4 | -5276.0 |
| WWP1 | -5266.0 |
| PSMC3 | -5262.0 |
| NPPA | -5260.0 |
| CDC73 | -5257.0 |
| ZNF611 | -5224.0 |
| DYRK2 | -5222.0 |
| ATM | -5218.0 |
| NR5A2 | -5201.0 |
| ZNF433 | -5114.0 |
| FKBP5 | -5112.0 |
| ZNF521 | -5110.0 |
| H2BC4 | -5066.0 |
| ZIM3 | -5063.0 |
| H3C8 | -5060.0 |
| PSME4 | -5053.0 |
| INTS1 | -5042.0 |
| SESN3 | -5041.0 |
| AXIN1 | -5023.0 |
| ZNF567 | -4969.0 |
| NELFE | -4964.0 |
| PRMT6 | -4927.0 |
| PRKCB | -4898.0 |
| ZNF234 | -4894.0 |
| ZNF211 | -4890.0 |
| PSMA5 | -4888.0 |
| ZNF225 | -4881.0 |
| INTS12 | -4879.0 |
| JMY | -4834.0 |
| ZNF282 | -4816.0 |
| IHH | -4808.0 |
| CDC23 | -4806.0 |
| TFDP2 | -4787.0 |
| ZNF548 | -4780.0 |
| ERCC3 | -4773.0 |
| CNOT4 | -4772.0 |
| CDC27 | -4761.0 |
| ZNF302 | -4759.0 |
| PSMD5 | -4711.0 |
| RAD51D | -4706.0 |
| PRMT5 | -4702.0 |
| CDKN2A | -4700.0 |
| CASP1 | -4699.0 |
| KMT2B | -4692.0 |
| NELFB | -4685.0 |
| RFC5 | -4673.0 |
| ZNF304 | -4665.0 |
| ESRRB | -4661.0 |
| ICE1 | -4657.0 |
| TNRC6C | -4643.0 |
| EED | -4626.0 |
| SP1 | -4623.0 |
| ZNF764 | -4620.0 |
| ZNF479 | -4600.0 |
| MLLT1 | -4589.0 |
| POLR2J | -4576.0 |
| AGRP | -4565.0 |
| ZNF141 | -4563.0 |
| MED20 | -4560.0 |
| FANCD2 | -4552.0 |
| CHD3 | -4537.0 |
| E2F7 | -4536.0 |
| H4C6 | -4534.0 |
| PMS2 | -4527.0 |
| CDC25C | -4507.0 |
| ZNF600 | -4506.0 |
| TGFB1 | -4499.0 |
| BTG1 | -4493.0 |
| AGO2 | -4490.0 |
| RAD1 | -4483.0 |
| CDK7 | -4467.0 |
| ZNF566 | -4450.0 |
| PLAGL1 | -4434.0 |
| KMT2E | -4425.0 |
| TSC2 | -4418.0 |
| RBL1 | -4357.0 |
| UBE2D1 | -4355.0 |
| THOC1 | -4354.0 |
| ITGA2B | -4353.0 |
| ZNF189 | -4352.0 |
| XPO1 | -4345.0 |
| ZFP90 | -4339.0 |
| PCGF5 | -4318.0 |
| NLRC4 | -4317.0 |
| TSC1 | -4313.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| PDPK1 | -4223.0 |
| PTEN | -4219.0 |
| BAX | -4215.0 |
| TACO1 | -4214.0 |
| OPRK1 | -4205.0 |
| H2BC17 | -4192.0 |
| TAF4B | -4176.0 |
| INTS7 | -4164.0 |
| POLR2B | -4142.0 |
| ZNF441 | -4119.0 |
| UBE2E1 | -4108.0 |
| WRN | -4104.0 |
| MED25 | -4099.0 |
| MYBL2 | -4072.0 |
| PHC2 | -4060.0 |
| ZNF564 | -4045.0 |
| TNRC6A | -4043.0 |
| RAD50 | -4035.0 |
| RNGTT | -3990.0 |
| TAF13 | -3982.0 |
| PSMD1 | -3979.0 |
| SREBF1 | -3956.0 |
| ZNF626 | -3950.0 |
| ZNF736 | -3925.0 |
| CNOT3 | -3917.0 |
| ZNF202 | -3916.0 |
| CCNK | -3901.0 |
| ZNF597 | -3887.0 |
| CAMK4 | -3886.0 |
| INTS8 | -3880.0 |
| H4C4 | -3867.0 |
| WDR33 | -3854.0 |
| GEM | -3843.0 |
| SOX9 | -3830.0 |
| BMI1 | -3827.0 |
| H2AJ | -3814.0 |
| TIGAR | -3786.0 |
| SRSF5 | -3776.0 |
| MED23 | -3774.0 |
| AFF4 | -3769.0 |
| GLI3 | -3745.0 |
| PMAIP1 | -3718.0 |
| HSPD1 | -3696.0 |
| ZNF786 | -3682.0 |
| RPRD2 | -3681.0 |
| ZNF154 | -3660.0 |
| ZNF793 | -3642.0 |
| RUNX2 | -3633.0 |
| ANAPC2 | -3617.0 |
| ZNF697 | -3616.0 |
| ZNF584 | -3614.0 |
| ZNF426 | -3593.0 |
| H2BC26 | -3582.0 |
| ZNF10 | -3577.0 |
| MED7 | -3569.0 |
| ZFP14 | -3485.0 |
| SRSF6 | -3471.0 |
| ZNF398 | -3434.0 |
| TCF3 | -3433.0 |
| KMT2D | -3430.0 |
| GTF2F1 | -3422.0 |
| CNOT7 | -3417.0 |
| TEAD3 | -3409.0 |
| ZNF160 | -3386.0 |
| FASLG | -3385.0 |
| MED17 | -3356.0 |
| ZNF544 | -3338.0 |
| APOE | -3335.0 |
| ZNF664 | -3333.0 |
| PHAX | -3324.0 |
| ZNF429 | -3294.0 |
| CREBBP | -3271.0 |
| TNFRSF18 | -3261.0 |
| IL2 | -3243.0 |
| FBXW7 | -3233.0 |
| ATF2 | -3228.0 |
| YBX1 | -3218.0 |
| TAF3 | -3206.0 |
| CNOT2 | -3204.0 |
| ANAPC15 | -3203.0 |
| TGIF1 | -3196.0 |
| CDKN1A | -3164.0 |
| NFE2 | -3154.0 |
| IWS1 | -3147.0 |
| HUS1 | -3130.0 |
| ZNF347 | -3121.0 |
| COX11 | -3091.0 |
| PSMC4 | -3089.0 |
| MAPKAP1 | -3088.0 |
| ELL2 | -3058.0 |
| LSM11 | -3033.0 |
| LAMTOR2 | -3018.0 |
| SKIC8 | -2957.0 |
| NFYC | -2954.0 |
| RING1 | -2953.0 |
| KRBOX5 | -2917.0 |
| ARID2 | -2910.0 |
| KRAS | -2902.0 |
| MAPK14 | -2900.0 |
| ZNF510 | -2893.0 |
| ZNF33A | -2883.0 |
| TFAP2B | -2839.0 |
| NDUFA4 | -2835.0 |
| VEGFA | -2830.0 |
| PSMB1 | -2799.0 |
| PRKAG2 | -2796.0 |
| ITGA4 | -2785.0 |
| ZNF430 | -2775.0 |
| TAF2 | -2754.0 |
| ZC3H11A | -2721.0 |
| MSH2 | -2712.0 |
| PRKCQ | -2709.0 |
| NFKB1 | -2707.0 |
| ZNF552 | -2679.0 |
| BDNF | -2666.0 |
| GSK3B | -2665.0 |
| SPP1 | -2661.0 |
| ZNF641 | -2640.0 |
| ZNF660 | -2620.0 |
| KAT2A | -2607.0 |
| LAMTOR4 | -2598.0 |
| GCK | -2566.0 |
| NR1H2 | -2553.0 |
| KCTD6 | -2539.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| GTF2A1 | -2470.0 |
| PRKAA1 | -2436.0 |
| PCGF2 | -2415.0 |
| TAF10 | -2411.0 |
| ZNF337 | -2401.0 |
| CALM1 | -2398.0 |
| AGO4 | -2358.0 |
| BIRC5 | -2354.0 |
| ZNF486 | -2348.0 |
| ZNF700 | -2346.0 |
| ZNF226 | -2345.0 |
| TAF9 | -2337.0 |
| CSTF2T | -2324.0 |
| SGK1 | -2322.0 |
| LAMTOR3 | -2319.0 |
| SYMPK | -2309.0 |
| CDK6 | -2302.0 |
| CCNH | -2298.0 |
| INTS14 | -2297.0 |
| UBE2D3 | -2295.0 |
| MGA | -2294.0 |
| PPM1D | -2231.0 |
| CDK1 | -2219.0 |
| INTS10 | -2212.0 |
| TCF12 | -2180.0 |
| PIP4K2C | -2178.0 |
| PIN1 | -2163.0 |
| ZNF589 | -2159.0 |
| GAD2 | -2158.0 |
| TCF7L2 | -2151.0 |
| PSMC6 | -2126.0 |
| AUTS2 | -2121.0 |
| ZNF197 | -2120.0 |
| PRKAB2 | -2119.0 |
| TNRC6B | -2096.0 |
| RPRD1B | -2080.0 |
| ZNF20 | -2072.0 |
| RNF34 | -2050.0 |
| ZNF684 | -2038.0 |
| CSNK2A2 | -2019.0 |
| RUNX1 | -2007.0 |
| MNAT1 | -1983.0 |
| ZNF565 | -1977.0 |
| KAT5 | -1955.0 |
| CAT | -1927.0 |
| ZNF324 | -1919.0 |
| ZNF573 | -1907.0 |
| SESN1 | -1880.0 |
| SOD2 | -1874.0 |
| HDAC3 | -1872.0 |
| GTF2H1 | -1823.0 |
| PML | -1804.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| ZNF606 | -1786.0 |
| ZNF224 | -1784.0 |
| CCNC | -1780.0 |
| GLS2 | -1770.0 |
| ZNF140 | -1746.0 |
| ZNF215 | -1725.0 |
| ZNF569 | -1717.0 |
| ZNF470 | -1707.0 |
| TAF8 | -1694.0 |
| PSMB9 | -1684.0 |
| ATR | -1677.0 |
| SNW1 | -1658.0 |
| MAX | -1655.0 |
| GTF2F2 | -1647.0 |
| ICE2 | -1641.0 |
| TAF11 | -1634.0 |
| LBR | -1592.0 |
| SMARCA2 | -1590.0 |
| ZNF273 | -1580.0 |
| H2AC8 | -1573.0 |
| BCL6 | -1545.0 |
| HES1 | -1537.0 |
| SCMH1 | -1534.0 |
| ZNF696 | -1531.0 |
| ZNF334 | -1504.0 |
| ZNF221 | -1491.0 |
| GATA2 | -1466.0 |
| POLR2H | -1463.0 |
| TAF1L | -1455.0 |
| PTPN4 | -1444.0 |
| SST | -1395.0 |
| NR1D2 | -1394.0 |
| PSMA3 | -1391.0 |
| ZNF133 | -1386.0 |
| ZNF213 | -1382.0 |
| ZNF776 | -1366.0 |
| RSPO3 | -1347.0 |
| TPX2 | -1344.0 |
| PAPOLA | -1301.0 |
| AGO3 | -1258.0 |
| BRD1 | -1254.0 |
| CCNT2 | -1252.0 |
| NCOR1 | -1234.0 |
| OPRM1 | -1202.0 |
| ZNF92 | -1174.0 |
| MLLT3 | -1156.0 |
| PSME3 | -1153.0 |
| CTNNB1 | -1147.0 |
| SSRP1 | -1143.0 |
| FOXO1 | -1136.0 |
| EZH2 | -1086.0 |
| RMI1 | -1065.0 |
| ELL | -1063.0 |
| KAT2B | -1030.0 |
| H2BC8 | -1029.0 |
| LAMTOR1 | -1023.0 |
| ZNF655 | -1022.0 |
| ANAPC11 | -1014.0 |
| PRKAA2 | -988.0 |
| SOCS3 | -973.0 |
| POMC | -950.0 |
| ZNF223 | -938.0 |
| NOP2 | -936.0 |
| TJP1 | -927.0 |
| RNF2 | -892.0 |
| AURKA | -876.0 |
| PAF1 | -856.0 |
| ZFP1 | -837.0 |
| PIP4K2A | -826.0 |
| CARM1 | -800.0 |
| SUPT6H | -788.0 |
| ZNF480 | -731.0 |
| SOCS4 | -728.0 |
| STAT1 | -717.0 |
| PPP1R13B | -704.0 |
| ATRIP | -702.0 |
| PPARGC1A | -698.0 |
| PIP4K2B | -676.0 |
| ZNF747 | -648.0 |
| INTS13 | -634.0 |
| ZFP69 | -621.0 |
| TXNIP | -589.0 |
| U2AF1L4 | -586.0 |
| BRD2 | -578.0 |
| TP53 | -548.0 |
| RORB | -546.0 |
| ITCH | -545.0 |
| POLR2C | -541.0 |
| RAD17 | -530.0 |
| YWHAE | -521.0 |
| CSTF1 | -499.0 |
| PCBP4 | -493.0 |
| ZNF689 | -485.0 |
| PSMA1 | -477.0 |
| MEAF6 | -451.0 |
| MED24 | -450.0 |
| TAF7 | -440.0 |
| E2F5 | -435.0 |
| ZNF169 | -429.0 |
| JAG1 | -420.0 |
| FIP1L1 | -408.0 |
| ZNF571 | -390.0 |
| MED31 | -383.0 |
| H2AZ2 | -340.0 |
| ZNF138 | -322.0 |
| RBFOX1 | -308.0 |
| TP53BP2 | -301.0 |
| PARP1 | -295.0 |
| ZKSCAN3 | -281.0 |
| ZNF419 | -277.0 |
| SKP1 | -264.0 |
| PSMB8 | -260.0 |
| COX5B | -246.0 |
| GAMT | -224.0 |
| UBA52 | -167.0 |
| MDC1 | -145.0 |
| LIFR | -143.0 |
| H3-3B | -135.0 |
| POLR2L | -110.0 |
| MED27 | -107.0 |
| RRAGA | -77.0 |
| EAF2 | -65.0 |
| LGALS3 | -58.0 |
| SATB2 | -54.0 |
| ZNF740 | -45.0 |
| PCNA | -40.0 |
| DNA2 | -36.0 |
| SIN3A | -32.0 |
| ZNF416 | -28.0 |
| CRADD | -22.0 |
| RFC3 | -16.0 |
| ZNF208 | -6.0 |
| NFYB | 8.0 |
| LEF1 | 20.0 |
| CPSF6 | 39.0 |
| SNAPC3 | 43.0 |
| SMARCA4 | 54.0 |
| SLC2A3 | 75.0 |
| MAPK1 | 78.0 |
| TNKS1BP1 | 89.0 |
| RPAP2 | 97.0 |
| KIT | 98.0 |
| MDM4 | 110.0 |
| YWHAG | 115.0 |
| RBPJ | 145.0 |
| BNIP3L | 160.0 |
| ZNF287 | 171.0 |
| CSF1R | 180.0 |
| ZNF620 | 191.0 |
| COX6B1 | 196.0 |
| ITGA5 | 225.0 |
| NPM1 | 252.0 |
| RXRB | 270.0 |
| IFNG | 281.0 |
| RRAGD | 285.0 |
| ZNF785 | 303.0 |
| RBL2 | 314.0 |
| ZFP2 | 321.0 |
| ZNF454 | 348.0 |
| NOC2L | 376.0 |
| RRAGC | 377.0 |
| NOTCH4 | 381.0 |
| CREB1 | 391.0 |
| APAF1 | 425.0 |
| L3MBTL2 | 443.0 |
| TP73 | 444.0 |
| PSMB10 | 447.0 |
| SMARCE1 | 449.0 |
| ZNF343 | 468.0 |
| CITED4 | 471.0 |
| ZNF446 | 473.0 |
| MYB | 481.0 |
| CNOT10 | 488.0 |
| ZNF461 | 494.0 |
| CLP1 | 507.0 |
| NEDD4L | 548.0 |
| YAF2 | 579.0 |
| THRB | 585.0 |
| MED10 | 648.0 |
| MBD3 | 653.0 |
| ELF2 | 656.0 |
| NR2C1 | 659.0 |
| SMAD1 | 719.0 |
| SRSF1 | 738.0 |
| PPARG | 783.0 |
| ERCC2 | 803.0 |
| MYC | 805.0 |
| WWTR1 | 809.0 |
| GATAD2A | 857.0 |
| PPP1R13L | 866.0 |
| SETD1B | 870.0 |
| H4C5 | 878.0 |
| HIVEP3 | 884.0 |
| PSMD12 | 901.0 |
| RAD51 | 905.0 |
| ZNF665 | 913.0 |
| CPSF3 | 915.0 |
| ZNF691 | 930.0 |
| CBFB | 943.0 |
| RFC4 | 973.0 |
| CENPJ | 1016.0 |
| CDC16 | 1047.0 |
| CCNT1 | 1082.0 |
| RARA | 1135.0 |
| HNF4G | 1141.0 |
| CDK9 | 1155.0 |
| ZNF250 | 1168.0 |
| ZNF708 | 1183.0 |
| TGFA | 1186.0 |
| ZNF34 | 1187.0 |
| CPSF7 | 1188.0 |
| RPA2 | 1210.0 |
| PSMD14 | 1213.0 |
| FZR1 | 1228.0 |
| GSR | 1300.0 |
| SUPT5H | 1305.0 |
| PHC3 | 1319.0 |
| CITED2 | 1320.0 |
| SIRT3 | 1331.0 |
| CBX5 | 1338.0 |
| CASC3 | 1346.0 |
| NOTCH3 | 1349.0 |
| SMYD2 | 1350.0 |
| ESR2 | 1376.0 |
| NFATC2 | 1398.0 |
| SMAD7 | 1406.0 |
| NR2C2 | 1413.0 |
| RRM2B | 1415.0 |
| ZNF70 | 1420.0 |
| SMARCD3 | 1464.0 |
| INTS6 | 1465.0 |
| NOTCH1 | 1475.0 |
| ZNF99 | 1477.0 |
| CTLA4 | 1512.0 |
| RARG | 1513.0 |
| ZNF624 | 1529.0 |
| SKI | 1545.0 |
| ZNF804B | 1594.0 |
| U2AF2 | 1614.0 |
| MAPK11 | 1621.0 |
| POLR2E | 1649.0 |
| CTSV | 1674.0 |
| ELOA | 1675.0 |
| SMARCD1 | 1681.0 |
| NR6A1 | 1691.0 |
| INTS11 | 1788.0 |
| ESR1 | 1789.0 |
| SEM1 | 1794.0 |
| CEBPB | 1814.0 |
| DDB2 | 1829.0 |
| NPAS4 | 1839.0 |
| COX20 | 1840.0 |
| NAMPT | 1845.0 |
| RPS27A | 1846.0 |
| GLS | 1860.0 |
| GP1BA | 1912.0 |
| HIPK2 | 1915.0 |
| H2BC3 | 1920.0 |
| ZNF561 | 1927.0 |
| SNRPE | 1962.0 |
| LEO1 | 1984.0 |
| ZNF713 | 1994.0 |
| NCBP2 | 2018.0 |
| HDAC10 | 2020.0 |
| GATAD2B | 2023.0 |
| ZNF18 | 2032.0 |
| CSNK2A1 | 2040.0 |
| CDK5 | 2048.0 |
| SUMO1 | 2052.0 |
| ZFHX3 | 2072.0 |
| MEF2C | 2082.0 |
| GTF2B | 2095.0 |
| TP53INP1 | 2111.0 |
| ITGBL1 | 2126.0 |
| MAGOHB | 2146.0 |
| ZNF679 | 2163.0 |
| CBX2 | 2171.0 |
| ATXN3 | 2178.0 |
| ZNF792 | 2180.0 |
| PSMC5 | 2183.0 |
| TBL1XR1 | 2184.0 |
| ZNF778 | 2198.0 |
| PSMD8 | 2235.0 |
| ELL3 | 2238.0 |
| JUN | 2245.0 |
| HEY1 | 2262.0 |
| ZNF761 | 2283.0 |
| ZNF599 | 2287.0 |
| COX4I1 | 2297.0 |
| ARNT | 2360.0 |
| EXO1 | 2396.0 |
| SETD9 | 2407.0 |
| MAML2 | 2412.0 |
| HDAC9 | 2423.0 |
| PPP2R5C | 2434.0 |
| MAPK3 | 2444.0 |
| MAML3 | 2506.0 |
| ZNF324B | 2522.0 |
| ZNF543 | 2542.0 |
| NABP2 | 2549.0 |
| NR2E3 | 2570.0 |
| ZFP37 | 2593.0 |
| TGIF2 | 2604.0 |
| THOC5 | 2643.0 |
| ZNF799 | 2674.0 |
| SNRPG | 2687.0 |
| SRSF4 | 2689.0 |
| SRSF3 | 2727.0 |
| ZNF136 | 2729.0 |
| H2BC1 | 2755.0 |
| RORA | 2763.0 |
| CAMK2D | 2790.0 |
| ZNF562 | 2795.0 |
| DEK | 2836.0 |
| ZNF175 | 2883.0 |
| ZNF583 | 2889.0 |
| ZNF540 | 2908.0 |
| ZNF443 | 2910.0 |
| E2F1 | 2922.0 |
| ING2 | 2929.0 |
| ZNF311 | 2952.0 |
| MSTN | 2969.0 |
| HDAC7 | 2984.0 |
| MLH1 | 3003.0 |
| BRIP1 | 3028.0 |
| SRRT | 3040.0 |
| MAGOH | 3080.0 |
| NUAK1 | 3088.0 |
| ZNF383 | 3093.0 |
| ZNF716 | 3100.0 |
| POU2F1 | 3114.0 |
| SMAD4 | 3126.0 |
| TAF6 | 3153.0 |
| USP2 | 3157.0 |
| TRIM63 | 3172.0 |
| ZNF45 | 3211.0 |
| COX16 | 3242.0 |
| POLDIP3 | 3251.0 |
| ZNF782 | 3257.0 |
| RELA | 3308.0 |
| SRSF11 | 3315.0 |
| ZNF205 | 3329.0 |
| BLK | 3349.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| RMI2 | 3423.0 |
| ZNF839 | 3433.0 |
| GADD45A | 3437.0 |
| SMARCC2 | 3457.0 |
| ZNF418 | 3477.0 |
| NBN | 3478.0 |
| SNRPD3 | 3490.0 |
| NR2F6 | 3551.0 |
| PRDM7 | 3573.0 |
| SNAPC5 | 3583.0 |
| PCGF6 | 3586.0 |
| FBXO32 | 3601.0 |
| CDC26 | 3611.0 |
| SIRT1 | 3614.0 |
| ZNF394 | 3622.0 |
| HNF4A | 3651.0 |
| THRA | 3700.0 |
| LRPPRC | 3717.0 |
| RXRA | 3719.0 |
| ZNF274 | 3825.0 |
| MED4 | 3828.0 |
| MED13 | 3849.0 |
| TXNRD1 | 3866.0 |
| ZNF677 | 3868.0 |
| BLM | 3894.0 |
| LMO1 | 3905.0 |
| H3C2 | 3915.0 |
| ZNF770 | 3936.0 |
| TP53AIP1 | 3952.0 |
| CDK13 | 4020.0 |
| PAX5 | 4088.0 |
| TEAD2 | 4094.0 |
| ZNF556 | 4112.0 |
| PPARD | 4113.0 |
| KCTD1 | 4115.0 |
| SUPT16H | 4125.0 |
| ZNF710 | 4136.0 |
| ZKSCAN8 | 4158.0 |
| ZNF558 | 4227.0 |
| CHD4 | 4230.0 |
| CCND2 | 4231.0 |
| NR1H3 | 4271.0 |
| TRIM28 | 4273.0 |
| LDB1 | 4278.0 |
| CCNE2 | 4280.0 |
| CCND1 | 4294.0 |
| ZNF688 | 4297.0 |
| ZNF529 | 4312.0 |
| RFC2 | 4313.0 |
| CCND3 | 4317.0 |
| H3-3A | 4335.0 |
| RETN | 4351.0 |
| TEAD1 | 4359.0 |
| YAP1 | 4364.0 |
| CCNA2 | 4366.0 |
| ZNF774 | 4371.5 |
| RBBP4 | 4375.0 |
| PRKAG3 | 4377.0 |
| CUL1 | 4399.0 |
| PPP2CA | 4421.0 |
| FAS | 4427.0 |
| PPP2R1A | 4431.0 |
| PRKAB1 | 4466.0 |
| ZNF267 | 4471.0 |
| RPA3 | 4481.0 |
| EGFR | 4497.0 |
| ELOC | 4538.0 |
| CPSF1 | 4549.0 |
| STUB1 | 4550.0 |
| NUDT21 | 4590.0 |
| L3MBTL1 | 4600.0 |
| CDK4 | 4604.0 |
| GRIN2B | 4606.0 |
| ZKSCAN4 | 4609.0 |
| DDX39A | 4662.0 |
| AKT1 | 4674.0 |
| ZNF442 | 4681.0 |
| ZFPM1 | 4711.0 |
| IQSEC3 | 4715.0 |
| SKP2 | 4760.0 |
| EPC1 | 4763.0 |
| RBFOX3 | 4799.0 |
| STK11 | 4832.0 |
| SARNP | 4846.0 |
| POLR2I | 4862.0 |
| AURKB | 4877.0 |
| MIR137 | 4889.0 |
| PSMB4 | 4971.0 |
| PTPN11 | 4975.0 |
| CAMK2B | 4977.0 |
| ZNF485 | 5007.0 |
| NABP1 | 5011.0 |
| BBC3 | 5039.0 |
| PRDX5 | 5040.0 |
| H4C3 | 5053.0 |
| ZNF37A | 5068.0 |
| TP53RK | 5080.0 |
| RARB | 5105.0 |
| SRF | 5110.0 |
| ZNF333 | 5113.0 |
| CDK2 | 5165.0 |
| ZNF557 | 5209.0 |
| PSMF1 | 5221.0 |
| CCNG1 | 5246.0 |
| ESRRA | 5247.0 |
| ZNF490 | 5277.0 |
| RYBP | 5284.0 |
| TAF12 | 5290.0 |
| GTF2H3 | 5295.0 |
| KMT5A | 5304.0 |
| PSMD7 | 5305.0 |
| SCO1 | 5321.0 |
| CAV1 | 5332.0 |
| KCTD15 | 5393.0 |
| PPM1A | 5430.0 |
| RFFL | 5469.0 |
| UBE2S | 5479.0 |
| ZNF560 | 5493.0 |
| MRE11 | 5531.0 |
| DAXX | 5566.0 |
| ZNF791 | 5582.0 |
| GTF2H5 | 5585.0 |
| CDC40 | 5642.0 |
| TTC5 | 5643.0 |
| MLST8 | 5663.0 |
| USP7 | 5667.0 |
| YWHAZ | 5701.0 |
| PERP | 5738.0 |
| MDM2 | 5757.0 |
| RAD9A | 5759.0 |
| HDAC5 | 5802.0 |
| PSMB2 | 5803.0 |
| PSMB7 | 5858.0 |
| PRKAG1 | 5864.0 |
| ZNF222 | 5899.0 |
| H3C3 | 5902.0 |
| TCF7L1 | 5910.0 |
| ESRRG | 5926.0 |
| ZNF649 | 5927.0 |
| DDIT3 | 5939.0 |
| ZNF692 | 5972.0 |
| RTF1 | 5978.0 |
| CNOT11 | 5993.0 |
| BID | 5996.0 |
| H3C1 | 6001.0 |
| ZNF550 | 6050.0 |
| ZNF559 | 6074.0 |
| SMAD6 | 6084.0 |
| ELOA2 | 6085.0 |
| ZNF114 | 6097.0 |
| LSM10 | 6106.0 |
| ZNF771 | 6108.0 |
| ZNF460 | 6122.0 |
| COX7C | 6164.0 |
| PRKACA | 6168.0 |
| ZNF582 | 6175.0 |
| ZNF563 | 6199.0 |
| PRR5 | 6225.0 |
| ARID3A | 6233.0 |
| GTF2E1 | 6262.0 |
| ZNF596 | 6282.0 |
| KCNIP3 | 6286.0 |
| MET | 6297.0 |
| SMARCC1 | 6298.0 |
| RET | 6334.0 |
| TAF5 | 6340.0 |
| GTF2H4 | 6387.0 |
| REST | 6437.0 |
| PRDM1 | 6438.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| FYTTD1 | 6538.0 |
| BCL2L11 | 6575.0 |
| SRC | 6605.0 |
| PSMD6 | 6616.0 |
| PBRM1 | 6627.0 |
| PSME2 | 6638.0 |
| NR5A1 | 6673.0 |
| RABGGTB | 6678.0 |
| UBC | 6700.0 |
| E2F4 | 6720.0 |
| ZNF613 | 6742.0 |
| ZNF25 | 6754.0 |
| RNMT | 6823.0 |
| RAD9B | 6859.0 |
| ZNF71 | 6864.0 |
| ZNF473 | 6883.0 |
| H2AC4 | 6905.0 |
| PLXNA4 | 6960.0 |
| GRIN2A | 6978.0 |
| SERPINB13 | 6981.0 |
| PSMA6 | 6984.0 |
| LAMTOR5 | 7006.0 |
| SUPT4H1 | 7014.0 |
| ZNF266 | 7042.0 |
| ZNF668 | 7057.0 |
| TAF15 | 7064.0 |
| MED15 | 7068.0 |
| ZNF101 | 7096.0 |
| DPY30 | 7120.0 |
| ZNF555 | 7126.0 |
| MOBP | 7133.0 |
| PRMT1 | 7139.0 |
| UBE2I | 7189.0 |
| ZNF709 | 7200.0 |
| THOC6 | 7219.0 |
| FURIN | 7240.0 |
| ZNF704 | 7253.0 |
| COX8A | 7254.0 |
| AGO1 | 7256.0 |
| TNFRSF10A | 7287.0 |
| PRELID1 | 7292.0 |
| VDR | 7351.0 |
| PIP4P1 | 7362.0 |
| RHEB | 7364.0 |
| SLBP | 7374.0 |
| TCEA1 | 7385.0 |
| TP63 | 7400.0 |
| H2BC21 | 7408.0 |
| COX19 | 7426.0 |
| CHEK2 | 7446.0 |
| RNU12 | 7476.0 |
| CCNE1 | 7482.0 |
| HDAC11 | 7512.0 |
| NR1H4 | 7526.0 |
| CDKN2B | 7557.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| ZNF483 | 7599.0 |
| SNAPC1 | 7656.0 |
| MAML1 | 7664.0 |
| YWHAH | 7669.0 |
| TEAD4 | 7672.0 |
| TP53I3 | 7674.0 |
| H2BC12 | 7676.0 |
| SRSF7 | 7689.0 |
| PPARGC1B | 7709.0 |
| ZNF585A | 7714.0 |
| THOC3 | 7729.5 |
| SKIL | 7754.0 |
| ACTL6B | 7777.0 |
| RNU11 | 7805.0 |
| ZNF256 | 7848.0 |
| NR4A1 | 7881.0 |
| SMAD3 | 7915.0 |
| FOXO6 | 7956.0 |
| ZNF235 | 7969.0 |
| PSMB3 | 8017.0 |
| ZNF706 | 8101.0 |
| ZNF17 | 8136.0 |
| ZNF143 | 8178.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| ZNF669 | 8217.0 |
| GPS2 | 8219.0 |
| PLK3 | 8223.0 |
| SMURF2 | 8269.0 |
| GLI2 | 8279.0 |
| YEATS4 | 8293.0 |
| POLR2D | 8323.0 |
| SNRPF | 8331.0 |
| STEAP3 | 8366.0 |
| MIR132 | 8383.0 |
| ELF1 | 8412.0 |
| MTA2 | 8451.0 |
| ZNF730 | 8485.0 |
| PTPN1 | 8604.0 |
| SPI1 | 8607.0 |
| ZNF385A | 8625.0 |
| SMARCD2 | 8676.0 |
| H2AC20 | 8750.0 |
| ZNF680 | 8770.0 |
| H4C1 | 8782.0 |
| PF4 | 8801.0 |
| SP7 | 8844.0 |
| POLR2F | 8864.0 |
| H2AZ1 | 8917.0 |
| POU2F2 | 8962.0 |
| ZNF320 | 8969.0 |
| OCLN | 9002.0 |
| ZNF254 | 9005.0 |
| RNU4ATAC | 9023.0 |
| BTG2 | 9024.0 |
| ZNF727 | 9033.0 |
| CAMK2G | 9035.0 |
| PRELID3A | 9065.0 |
| NRBF2 | 9098.0 |
| CDK5R1 | 9119.0 |
| POLR2G | 9208.0 |
| IL2RA | 9214.0 |
| COX14 | 9300.0 |
| ZNF440 | 9318.0 |
| H2AC14 | 9376.0 |
| ABCA6 | 9402.0 |
| PIDD1 | 9423.0 |
| MMP13 | 9430.0 |
| NPY | 9433.0 |
| NDRG1 | 9447.0 |
| ZNF212 | 9464.0 |
| H4C9 | 9492.0 |
| TNFRSF10B | 9494.0 |
| PSMA7 | 9563.0 |
| NELFCD | 9621.0 |
| COX5A | 9635.0 |
| COX6A1 | 9648.0 |
| CTSK | 9665.0 |
| ZNF286A | 9745.0 |
| PSME1 | 9765.0 |
| ZNF528 | 9785.0 |
| ARNT2 | 9786.0 |
| RGCC | 9967.0 |
| ZNF614 | 9978.0 |
| MIR27A | 10004.0 |
| H4C12 | 10027.0 |
| SESN2 | 10076.0 |
| ZNF432 | 10080.0 |
| ZFP69B | 10084.0 |
| ANAPC1 | 10085.0 |
| RUNX3 | 10093.0 |
| MIR24-2 | 10120.0 |
| H2BC14 | 10168.0 |
| COL1A1 | 10211.0 |
| MED26 | 10220.0 |
| ZNF554 | 10233.0 |
| CAMK2A | 10289.0 |
| RBX1 | 10301.0 |
| BGLAP | 10313.0 |
| PCK1 | 10322.0 |
| SFN | 10357.0 |
| NR1I3 | 10372.0 |
| CSF2 | 10380.0 |
| ELOB | 10514.0 |
| PVALB | 10567.0 |
| BCL2L14 | 10568.0 |
| IL3 | 10586.0 |
| UCMA | 10602.0 |
| G6PC1 | 10846.0 |
| MYL9 | 10913.0 |
| ZNF717 | 10955.0 |
| RORC | 10972.0 |
| INS | 11042.0 |
| SCO2 | 11048.0 |
| ZNF300 | 11057.0 |
| NR0B2 | 11117.0 |
REACTOME_SENSORY_PERCEPTION
| 1581 | |
|---|---|
| set | REACTOME_SENSORY_PERCEPTION |
| setSize | 555 |
| pANOVA | 2.08e-14 |
| s.dist | 0.19 |
| p.adjustANOVA | 1.71e-11 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6Q1 | 11526 |
| OR2T3 | 11520 |
| OR2V1 | 11508 |
| OR8A1 | 11481 |
| OR5M10 | 11436 |
| OR8U3 | 11430 |
| OR4C12 | 11429 |
| APOC3 | 11415 |
| OR2S2 | 11382 |
| OR1K1 | 11368 |
| OR2M7 | 11362 |
| OR2AG1 | 11346 |
| OR4A47 | 11331 |
| OR2L5 | 11292 |
| OR51F1 | 11264 |
| OR56B4 | 11197 |
| OR1N2 | 11196 |
| OR2L3 | 11182 |
| OR2A5 | 11152 |
| OTOP1 | 11125 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6Q1 | 11526.0 |
| OR2T3 | 11520.0 |
| OR2V1 | 11508.0 |
| OR8A1 | 11481.0 |
| OR5M10 | 11436.0 |
| OR8U3 | 11430.0 |
| OR4C12 | 11429.0 |
| APOC3 | 11415.0 |
| OR2S2 | 11382.0 |
| OR1K1 | 11368.0 |
| OR2M7 | 11362.0 |
| OR2AG1 | 11346.0 |
| OR4A47 | 11331.0 |
| OR2L5 | 11292.0 |
| OR51F1 | 11264.0 |
| OR56B4 | 11197.0 |
| OR1N2 | 11196.0 |
| OR2L3 | 11182.0 |
| OR2A5 | 11152.0 |
| OTOP1 | 11125.0 |
| OR1N1 | 11114.0 |
| OR10P1 | 11095.0 |
| OR2AK2 | 11078.0 |
| OR5A2 | 11069.0 |
| OR6C65 | 11067.0 |
| TRPM5 | 11038.0 |
| OR2L2 | 11028.0 |
| GRXCR1 | 11015.0 |
| OR51G2 | 11014.0 |
| OR10J1 | 11011.0 |
| CNGA4 | 10986.0 |
| OR10Z1 | 10968.0 |
| OR6C4 | 10956.0 |
| OR5T3 | 10949.0 |
| GNGT1 | 10937.0 |
| OR5D13 | 10935.0 |
| OR2M5 | 10922.0 |
| OR51G1 | 10885.0 |
| OR10AG1 | 10878.0 |
| OR5H2 | 10875.0 |
| CALHM3 | 10855.0 |
| OR56B1 | 10834.0 |
| APOA4 | 10814.0 |
| OR4C3 | 10810.0 |
| OR51A7 | 10807.0 |
| OR4N5 | 10802.0 |
| OR51S1 | 10800.0 |
| OR2T27 | 10759.0 |
| OR4C15 | 10744.0 |
| OR5L1 | 10741.0 |
| OR1E2 | 10728.0 |
| OR5T2 | 10725.0 |
| OR6B2 | 10719.0 |
| OR4B1 | 10709.0 |
| OR10G9 | 10685.0 |
| OR1S2 | 10668.0 |
| OR4N2 | 10667.0 |
| OR5H6 | 10631.0 |
| OR10A7 | 10623.0 |
| OR8G5 | 10583.0 |
| EPS8L2 | 10549.0 |
| OR2H2 | 10546.0 |
| OR6C2 | 10535.0 |
| OR2T6 | 10532.0 |
| HSD17B6 | 10516.0 |
| OR7D4 | 10513.0 |
| TAS1R3 | 10502.0 |
| OR2D2 | 10496.0 |
| OR8G1 | 10492.0 |
| OR5A1 | 10488.0 |
| OR8B12 | 10477.0 |
| OR2K2 | 10440.0 |
| OR5L2 | 10439.0 |
| OR8D4 | 10419.0 |
| OR2T12 | 10344.0 |
| OR10T2 | 10343.0 |
| KCNMB1 | 10337.0 |
| OR5P2 | 10306.0 |
| AKR1C4 | 10294.0 |
| PDE6G | 10283.0 |
| OR6C74 | 10273.0 |
| OR6B1 | 10264.0 |
| OR8I2 | 10228.0 |
| TAS2R46 | 10225.0 |
| OR5M1 | 10192.0 |
| XIRP2 | 10160.0 |
| OR2M2 | 10157.0 |
| SCN3A | 10156.0 |
| OR52A1 | 10153.0 |
| OR13C4 | 10131.0 |
| OR10S1 | 10114.0 |
| OR6C1 | 10077.0 |
| TAS2R16 | 10005.0 |
| OR5V1 | 9989.0 |
| OR8S1 | 9966.0 |
| OR4K15 | 9959.0 |
| STRA6 | 9950.0 |
| TAS2R41 | 9937.0 |
| OR4D6 | 9858.0 |
| OR2Y1 | 9855.0 |
| OR1J4 | 9837.0 |
| OR10G3 | 9831.0 |
| FSCN2 | 9822.0 |
| OR4K13 | 9754.0 |
| OR6A2 | 9751.0 |
| OR51F2 | 9730.0 |
| OR1F1 | 9694.0 |
| OR1G1 | 9651.0 |
| OR5H15 | 9636.0 |
| OR4M1 | 9625.0 |
| OR8K5 | 9620.0 |
| OR4X1 | 9589.0 |
| OTOGL | 9583.0 |
| OR4K2 | 9582.0 |
| OR52N2 | 9556.0 |
| OR8D2 | 9530.0 |
| OR4F6 | 9496.0 |
| OR2L8 | 9473.0 |
| OR2M3 | 9448.0 |
| GNG13 | 9443.0 |
| GNB3 | 9437.0 |
| OR10G4 | 9407.0 |
| GNAT1 | 9398.0 |
| OR8B8 | 9351.0 |
| OR5M3 | 9325.0 |
| GUCA1A | 9307.0 |
| MYO3B | 9225.0 |
| OR2H1 | 9219.0 |
| OR5I1 | 9206.0 |
| CDH23 | 9123.0 |
| OR10W1 | 9113.0 |
| OR9G1 | 9104.5 |
| OR9G9 | 9104.5 |
| PLB1 | 9093.0 |
| OR10A4 | 9087.0 |
| OR2A2 | 9077.0 |
| OR7C1 | 9075.0 |
| OR4A16 | 9052.0 |
| TAS2R38 | 9027.0 |
| OR4D9 | 9004.0 |
| KCNQ4 | 8920.0 |
| OR13A1 | 8896.0 |
| SDC3 | 8890.0 |
| OR51B4 | 8882.0 |
| DHRS9 | 8869.0 |
| OR9Q2 | 8850.0 |
| OR51V1 | 8753.0 |
| TTR | 8727.0 |
| OR4D11 | 8663.0 |
| SDC1 | 8643.0 |
| OR1J2 | 8637.0 |
| RBP3 | 8627.0 |
| OR56A1 | 8572.0 |
| MYO7A | 8554.0 |
| OR2T33 | 8542.0 |
| OR1E1 | 8503.0 |
| OR52A5 | 8500.0 |
| OR7A5 | 8482.0 |
| OR51B2 | 8469.0 |
| OR13F1 | 8467.0 |
| OR12D3 | 8407.0 |
| OR8U8 | 8388.0 |
| RCVRN | 8387.0 |
| EBF1 | 8381.0 |
| OTOF | 8363.0 |
| TAS1R2 | 8362.0 |
| USH1C | 8332.0 |
| TAS2R1 | 8330.0 |
| RTP2 | 8322.0 |
| OR1A2 | 8296.0 |
| HSPG2 | 8255.0 |
| ANO2 | 8254.0 |
| GPC6 | 8172.0 |
| GRM4 | 8116.0 |
| TAS1R1 | 8083.0 |
| OR51B5 | 8064.0 |
| CALHM1 | 8053.0 |
| OR2L13 | 8041.0 |
| OR6S1 | 8002.0 |
| OR2W3 | 8000.0 |
| OR2T4 | 7973.0 |
| OR51M1 | 7857.0 |
| SCN9A | 7779.0 |
| TRPM4 | 7775.0 |
| OR12D2 | 7718.0 |
| ATP2B2 | 7660.0 |
| OR11A1 | 7637.0 |
| STX1A | 7633.0 |
| OTOG | 7620.0 |
| OR10H3 | 7607.0 |
| OR11H6 | 7574.0 |
| ESPNL | 7532.0 |
| CACNA2D2 | 7485.0 |
| BSN | 7474.0 |
| TAS2R14 | 7427.0 |
| OR10K2 | 7424.0 |
| OR10C1 | 7405.0 |
| OR4C46 | 7380.0 |
| PNLIP | 7353.0 |
| OR9G4 | 7332.0 |
| OR10H2 | 7308.0 |
| OR2T11 | 7206.0 |
| OR1B1 | 7199.0 |
| OR5T1 | 7198.0 |
| OR5B3 | 7194.0 |
| SCN2B | 7152.0 |
| CACNA1D | 7137.0 |
| ESPN | 7065.0 |
| OR2W1 | 7059.0 |
| OR1C1 | 7020.0 |
| OR13C9 | 6996.0 |
| OR8K1 | 6953.0 |
| OR6X1 | 6942.0 |
| SLC24A1 | 6937.0 |
| GPC5 | 6842.0 |
| OR10A2 | 6809.0 |
| ABCA4 | 6785.0 |
| STRC | 6779.0 |
| OR5AR1 | 6703.0 |
| OR13C2 | 6695.0 |
| OR4K17 | 6618.0 |
| CNGB1 | 6587.0 |
| OR51D1 | 6577.0 |
| OR2F1 | 6574.0 |
| APOC2 | 6566.0 |
| LRP1 | 6557.0 |
| OR9A4 | 6452.0 |
| OR2B3 | 6432.0 |
| OR8U1 | 6414.0 |
| OR52E2 | 6360.0 |
| OR4S1 | 6347.0 |
| RBP2 | 6239.0 |
| OR10H5 | 6166.0 |
| OR10J5 | 6146.0 |
| OR6C3 | 6126.0 |
| OR2G6 | 6072.0 |
| OR14J1 | 6051.0 |
| OR2AP1 | 6040.0 |
| OR52B6 | 6019.0 |
| RPE65 | 5998.0 |
| OR9Q1 | 5976.0 |
| SCN4B | 5924.0 |
| SCNN1B | 5903.0 |
| RLBP1 | 5820.0 |
| RTP1 | 5708.0 |
| LHFPL5 | 5660.0 |
| AKR1C3 | 5657.0 |
| OR4D1 | 5633.0 |
| AKR1B10 | 5616.0 |
| OR5W2 | 5572.0 |
| AGRN | 5535.0 |
| OR56A4 | 5518.0 |
| PCDH15 | 5466.0 |
| OR10G2 | 5461.0 |
| OR2D3 | 5407.0 |
| GPC2 | 5386.0 |
| TAS2R40 | 5383.0 |
| EPS8 | 5342.0 |
| ACTB | 5155.0 |
| PDE6A | 5143.0 |
| GRK1 | 5106.0 |
| GSN | 5071.0 |
| CTBP2 | 5050.0 |
| WHRN | 4923.0 |
| OR6B3 | 4879.0 |
| OR5D16 | 4868.0 |
| OR51E2 | 4861.0 |
| OR10K1 | 4826.0 |
| ACTG1 | 4819.0 |
| OR13C8 | 4812.0 |
| OR10V1 | 4788.0 |
| SDC4 | 4768.0 |
| KCNMA1 | 4594.0 |
| GRXCR2 | 4528.0 |
| OR2F2 | 4517.0 |
| OR5D14 | 4508.0 |
| SDR9C7 | 4483.0 |
| LRRC52 | 4412.0 |
| LDB1 | 4278.0 |
| RDH8 | 4211.0 |
| OR5J2 | 4161.0 |
| PCLO | 4122.0 |
| CAMKMT | 4120.0 |
| GUCY2D | 4045.0 |
| TAS2R43 | 4016.0 |
| METAP2 | 4012.0 |
| CABP2 | 4000.0 |
| OR6N2 | 3985.0 |
| OR52E4 | 3984.0 |
| OR51B6 | 3980.0 |
| OR5K4 | 3891.0 |
| RDH10 | 3882.0 |
| OR5B12 | 3863.0 |
| OR4A15 | 3837.0 |
| OR4L1 | 3819.0 |
| TMIE | 3737.0 |
| OR14I1 | 3625.0 |
| OR7G3 | 3544.0 |
| OR4X2 | 3542.0 |
| CACNB2 | 3442.0 |
| SCN1B | 3289.0 |
| OR10A6 | 3165.0 |
| SCN2A | 3141.0 |
| METAP1 | 3102.0 |
| OR9K2 | 3046.0 |
| OR1A1 | 2995.0 |
| OR5F1 | 2902.0 |
| GPIHBP1 | 2894.0 |
| RBP1 | 2812.0 |
| OR3A3 | 2786.0 |
| GRM1 | 2773.0 |
| CLIC5 | 2771.0 |
| OR6C70 | 2754.0 |
| ADCY3 | 2673.0 |
| TAS2R8 | 2612.0 |
| RDH12 | 2548.0 |
| MYO15A | 2490.0 |
| LRP2 | 2457.0 |
| MYH9 | 2365.0 |
| REEP1 | 2357.0 |
| RDH16 | 2272.0 |
| RAB3A | 2157.0 |
| SCNN1A | 2148.0 |
| OR52K2 | 2114.0 |
| BCO1 | 2090.0 |
| OR51E1 | 2044.0 |
| OR52M1 | 2024.0 |
| GPC1 | 1943.0 |
| OR2B11 | 1916.0 |
| OR52D1 | 1878.0 |
| OR5B2 | 1870.0 |
| RHO | 1851.0 |
| OR10H1 | 1841.0 |
| OR51Q1 | 1807.0 |
| SLC17A8 | 1673.0 |
| OR2T8 | 1660.0 |
| SAG | 1606.0 |
| OR2AT4 | 1558.0 |
| OR4K14 | 1544.0 |
| SDC2 | 1493.0 |
| OR1L1 | 1423.0 |
| EPB41L3 | 1317.0 |
| OR4K5 | 1007.0 |
| CAPZA2 | 982.0 |
| PDE6B | 892.0 |
| OR7C2 | 848.0 |
| CAPZA1 | 768.0 |
| OR6K2 | 764.0 |
| OR1L3 | 704.0 |
| OR52N1 | 676.0 |
| MYO3A | 658.0 |
| CABP1 | 637.0 |
| TAS2R13 | 622.0 |
| OR11G2 | 427.0 |
| CNGA1 | 424.0 |
| DNAJC5 | 333.0 |
| OR13C3 | 317.0 |
| APOM | 290.0 |
| GNAL | 213.0 |
| OR51I1 | 187.0 |
| APOA1 | 129.0 |
| OR52B2 | 68.0 |
| OR8B2 | -5.0 |
| RIPOR2 | -26.0 |
| OR5D18 | -73.0 |
| OR2B6 | -249.0 |
| OR5AS1 | -259.0 |
| OR3A2 | -280.0 |
| NMT2 | -282.0 |
| GRK7 | -300.0 |
| LRP8 | -305.0 |
| TWF1 | -374.0 |
| OR5B17 | -490.0 |
| GNAT3 | -540.0 |
| SCNN1D | -588.0 |
| MYO1C | -633.0 |
| OR51L1 | -975.0 |
| OR4F15 | -982.0 |
| PRKCA | -1066.0 |
| RDH5 | -1179.0 |
| FNTB | -1232.0 |
| TPRN | -1363.0 |
| OR7A17 | -1468.0 |
| TMC1 | -1691.0 |
| OR10G7 | -1753.0 |
| USH1G | -1785.0 |
| ATP2B1 | -1805.0 |
| OR10J3 | -1888.0 |
| OR13D1 | -2074.0 |
| LRP10 | -2084.0 |
| TAS2R39 | -2086.0 |
| OR52I2 | -2150.0 |
| OR10A5 | -2168.0 |
| BCO2 | -2220.0 |
| OR10H4 | -2234.0 |
| OR7G1 | -2296.0 |
| CALM1 | -2398.0 |
| OR2A12 | -2425.0 |
| OR13J1 | -2493.0 |
| PJVK | -2544.0 |
| PRKCQ | -2709.0 |
| TWF2 | -2739.0 |
| EPB41L1 | -2752.0 |
| OR5AU1 | -2805.0 |
| OR1D2 | -2814.0 |
| AKR1C1 | -2853.0 |
| PLS1 | -3008.0 |
| GNB1 | -3044.0 |
| SCNN1G | -3163.0 |
| SPTAN1 | -3167.0 |
| OR4A5 | -3180.0 |
| OR6K3 | -3182.0 |
| OR6K6 | -3230.0 |
| OR5C1 | -3300.0 |
| APOE | -3335.0 |
| OR8J1 | -3357.0 |
| OR6C75 | -3482.0 |
| EZR | -3787.0 |
| GNB5 | -4000.0 |
| CAPZB | -4153.0 |
| GRK4 | -4237.0 |
| OR9I1 | -4242.0 |
| OR8J3 | -4284.0 |
| TRIOBP | -4291.0 |
| RETSAT | -4306.0 |
| RGS9 | -4406.0 |
| TAS2R7 | -4498.0 |
| RGS9BP | -4658.0 |
| OR5AN1 | -4684.0 |
| OR5M11 | -4694.0 |
| OR14C36 | -4698.0 |
| GUCA1B | -4793.0 |
| FNTA | -4798.0 |
| OR5B21 | -4841.0 |
| PLCB2 | -4847.0 |
| RDX | -4906.0 |
| OR5K1 | -4952.0 |
| SPTBN1 | -4995.0 |
| CYP4V2 | -5039.0 |
| OR13G1 | -5061.0 |
| SNAP25 | -5077.0 |
| KCNJ2 | -5206.0 |
| OR6Y1 | -5211.0 |
| CIB2 | -5313.0 |
| OR56A3 | -5392.0 |
| OR9A2 | -5558.0 |
| LDLR | -5785.0 |
| TAS2R20 | -5840.0 |
| DHRS3 | -5873.0 |
| OR10G8 | -6149.0 |
| OR10Q1 | -6168.0 |
| SLC26A5 | -6185.0 |
| OR5M9 | -6221.0 |
| OR4E2 | -6347.0 |
| OR4D2 | -6446.0 |
| OR51I2 | -6462.0 |
| OR52W1 | -6539.0 |
| OR51T1 | -6576.0 |
| OR4D10 | -6638.0 |
| OR1M1 | -6663.0 |
| TAS2R5 | -6695.0 |
| TAS2R3 | -6822.0 |
| OR5AP2 | -6823.0 |
| OR10X1 | -6889.0 |
| ITPR3 | -6916.0 |
| OR4K1 | -6988.0 |
| OR2M4 | -7001.0 |
| OR1L6 | -7242.0 |
| OR2G2 | -7259.0 |
| TAS2R30 | -7323.0 |
| OR2C1 | -7329.0 |
| OR52R1 | -7469.0 |
| OR6V1 | -7514.0 |
| GUCA1C | -7578.0 |
| KCNN2 | -7597.0 |
| RDH11 | -7608.0 |
| OR1I1 | -7610.0 |
| OR5P3 | -7653.0 |
| TMC2 | -7740.0 |
| OR7D2 | -7744.0 |
| OR2Z1 | -7772.0 |
| NAPEPLD | -7786.0 |
| OR8B4 | -7909.0 |
| OR52H1 | -7934.0 |
| LPL | -7972.0 |
| OR4C6 | -8001.0 |
| OR8K3 | -8006.0 |
| OR52E8 | -8076.0 |
| OR6F1 | -8092.0 |
| OR52I1 | -8148.0 |
| VAMP2 | -8316.0 |
| OR5AK2 | -8345.0 |
| OR2V2 | -8375.0 |
| TAS2R10 | -8397.0 |
| OR2B2 | -8425.0 |
| NMT1 | -8448.0 |
| OR6N1 | -8451.0 |
| OR10A3 | -8505.0 |
| APOA2 | -8511.0 |
| OR2G3 | -8522.0 |
| OR2J2 | -8617.0 |
| APOB | -8669.0 |
| OR5K2 | -8686.0 |
| OR7A10 | -8699.0 |
| OR6M1 | -8844.0 |
| OR2A14 | -8899.0 |
| OR1L8 | -8972.0 |
| OR3A1 | -8985.0 |
| OR1S1 | -9151.0 |
| OR4C45 | -9179.0 |
| OR5M8 | -9205.0 |
| TAS2R31 | -9210.0 |
| TAS2R50 | -9218.0 |
| OR2C3 | -9237.0 |
| OR6T1 | -9317.0 |
| OR1Q1 | -9338.0 |
| OR11H4 | -9369.0 |
| OR6P1 | -9375.0 |
| CLPS | -9429.0 |
| LRP12 | -9432.0 |
| OPN1SW | -9449.0 |
| LHX2 | -9462.0 |
| OR6C68 | -9469.0 |
| CHRNA9 | -9518.0 |
| OR2AE1 | -9559.0 |
| CHRNA10 | -9591.0 |
| OR52J3 | -9657.0 |
| OR7G2 | -9698.0 |
| OR11L1 | -9725.0 |
| OR51A2 | -9729.0 |
| OR1J1 | -9739.0 |
| OR6C76 | -9740.0 |
| OR52L1 | -9752.0 |
| LRAT | -9753.0 |
| HSD17B1 | -9795.0 |
| OR7E24 | -9826.0 |
| OR56A5 | -9853.0 |
| OR6C6 | -9860.0 |
| OR8H1 | -9867.0 |
| OR5AC2 | -9882.0 |
| OR1L4 | -9883.0 |
| OR2AG2 | -9932.0 |
| OR8D1 | -9966.0 |
| OR52E6 | -9980.0 |
| OR4C16 | -10005.0 |
| RBP4 | -10032.0 |
| TAS2R4 | -10102.0 |
| OR2T1 | -10139.0 |
| OR52K1 | -10237.0 |
| OR4D5 | -10252.0 |
| OR10AD1 | -10274.0 |
| OR8H3 | -10391.0 |
| OR14A16 | -10393.0 |
| OR5K3 | -10407.0 |
| OR5H1 | -10415.0 |
REACTOME_CELL_CYCLE
| 190 | |
|---|---|
| set | REACTOME_CELL_CYCLE |
| setSize | 666 |
| pANOVA | 2.09e-12 |
| s.dist | -0.16 |
| p.adjustANOVA | 9.44e-10 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| SYCP3 | -10065.0 |
| CC2D1B | -9830.0 |
| CDK11A | -9721.0 |
| CHMP2B | -9643.0 |
| FOXM1 | -9614.0 |
| CHEK1 | -9546.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| CDC14A | -9420.0 |
| GOLGA2 | -9392.0 |
| HDAC1 | -9320.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| SYCP3 | -10065.0 |
| CC2D1B | -9830.0 |
| CDK11A | -9721.0 |
| CHMP2B | -9643.0 |
| FOXM1 | -9614.0 |
| CHEK1 | -9546.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| CDC14A | -9420.0 |
| GOLGA2 | -9392.0 |
| HDAC1 | -9320.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
| TFDP1 | -9109.0 |
| POM121C | -9098.0 |
| TUBB4B | -9023.0 |
| TOP2A | -9001.0 |
| PHF20 | -8977.0 |
| MSH4 | -8962.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| LEMD2 | -8856.0 |
| RHNO1 | -8854.0 |
| HJURP | -8786.0 |
| HERC2 | -8765.0 |
| REC8 | -8756.0 |
| VPS4A | -8736.0 |
| RB1 | -8714.0 |
| RAB2A | -8702.0 |
| TUBA1C | -8675.0 |
| ANAPC5 | -8661.0 |
| CENPH | -8616.0 |
| LIN9 | -8611.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| PSMB11 | -8512.0 |
| TUBG2 | -8420.0 |
| MLH3 | -8370.0 |
| NSD2 | -8330.0 |
| NCAPD2 | -8303.0 |
| TUBA3E | -8293.0 |
| POM121 | -8267.0 |
| CEP192 | -8256.0 |
| MZT2A | -8243.0 |
| H2BC13 | -8199.0 |
| MCM6 | -8182.0 |
| TERF1 | -8123.0 |
| H4C16 | -8109.0 |
| NDEL1 | -8074.0 |
| CDC6 | -8067.0 |
| MZT1 | -8047.0 |
| SYCP2 | -8041.0 |
| YWHAB | -8002.0 |
| PSMC1 | -7848.0 |
| ABRAXAS1 | -7840.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| BORA | -7784.0 |
| CHMP4C | -7757.0 |
| RPA1 | -7755.0 |
| POLE | -7738.0 |
| MAU2 | -7729.0 |
| CEP164 | -7722.0 |
| BLZF1 | -7718.0 |
| CENPO | -7707.0 |
| CDK11B | -7666.0 |
| H2AX | -7648.0 |
| RRM2 | -7580.0 |
| CKAP5 | -7526.0 |
| GORASP2 | -7497.0 |
| PPP2R2D | -7485.0 |
| DYNLL2 | -7477.0 |
| TOPBP1 | -7459.0 |
| POLE2 | -7447.0 |
| POLR2A | -7443.0 |
| ZWINT | -7442.0 |
| GINS3 | -7376.0 |
| H3C6 | -7372.0 |
| PSMD13 | -7362.0 |
| BTRC | -7343.0 |
| KIF2C | -7337.0 |
| GORASP1 | -7335.0 |
| BRCA2 | -7322.0 |
| ORC2 | -7207.0 |
| NUP214 | -7186.0 |
| PTTG1 | -7163.0 |
| CHMP4B | -7159.0 |
| NCAPH2 | -7155.0 |
| MCM10 | -7149.0 |
| EP300 | -7126.0 |
| RUVBL1 | -7114.0 |
| SPAST | -7098.0 |
| POLD2 | -7092.0 |
| ODF2 | -7061.0 |
| NCAPG2 | -7020.0 |
| CDKN1B | -6954.0 |
| CCNB2 | -6945.0 |
| NUMA1 | -6884.0 |
| ABL1 | -6881.0 |
| CENPC | -6867.0 |
| NUP88 | -6865.0 |
| LCMT1 | -6864.0 |
| CDC7 | -6856.0 |
| SMARCA5 | -6825.0 |
| ANKLE2 | -6706.0 |
| TOP3A | -6676.0 |
| NCAPD3 | -6668.0 |
| RFC1 | -6662.0 |
| CDC25A | -6647.0 |
| PLK1 | -6633.0 |
| PPP1CC | -6627.0 |
| TUBA4A | -6626.0 |
| PSMD3 | -6608.0 |
| SMC2 | -6571.0 |
| DCTN3 | -6556.0 |
| SUN1 | -6555.0 |
| NUP42 | -6551.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| PCM1 | -6483.0 |
| BRCA1 | -6477.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| CEP152 | -6444.0 |
| CHTF8 | -6438.0 |
| PSMD4 | -6409.0 |
| POLR2K | -6386.0 |
| CEP131 | -6383.0 |
| E2F6 | -6358.0 |
| PSMB5 | -6339.0 |
| TUBB2B | -6314.0 |
| LIN54 | -6191.0 |
| ORC6 | -6177.0 |
| CEP72 | -6174.0 |
| TINF2 | -6121.0 |
| CENPF | -6110.0 |
| CSNK2B | -6080.0 |
| ZW10 | -6072.0 |
| MAD2L1 | -6059.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| HAUS5 | -6025.0 |
| TUBB2A | -5979.0 |
| ESPL1 | -5959.0 |
| NUP210 | -5812.0 |
| TUBGCP5 | -5800.0 |
| ANAPC7 | -5789.0 |
| H2AC6 | -5775.0 |
| CLIP1 | -5755.0 |
| H2BC15 | -5694.0 |
| AKT3 | -5680.0 |
| TUBGCP6 | -5669.0 |
| LMNB1 | -5639.0 |
| RNF168 | -5628.0 |
| H3C11 | -5538.0 |
| TPR | -5490.0 |
| SIRT2 | -5451.0 |
| H3-4 | -5447.0 |
| YWHAQ | -5428.0 |
| AKT2 | -5419.0 |
| ORC1 | -5405.0 |
| CLASP1 | -5346.0 |
| JAK2 | -5312.0 |
| H2BC6 | -5295.0 |
| PSMC3 | -5262.0 |
| PPP1R12A | -5243.0 |
| ATM | -5218.0 |
| DSCC1 | -5205.0 |
| CNEP1R1 | -5168.0 |
| PPP2R5E | -5142.0 |
| DYNC1I2 | -5131.0 |
| CHMP2A | -5098.0 |
| CEP63 | -5092.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| E2F2 | -5059.0 |
| PSME4 | -5053.0 |
| TUBAL3 | -5043.0 |
| TUBA4B | -5020.0 |
| CEP43 | -4973.0 |
| DIDO1 | -4958.0 |
| DYRK1A | -4936.0 |
| AJUBA | -4908.0 |
| PRKCB | -4898.0 |
| PSMA5 | -4888.0 |
| CHMP3 | -4842.0 |
| CDC23 | -4806.0 |
| UBE2V2 | -4803.0 |
| TFDP2 | -4787.0 |
| MIS18A | -4777.0 |
| CDC27 | -4761.0 |
| SDCCAG8 | -4735.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| HSPA2 | -4704.0 |
| CDKN2A | -4700.0 |
| RFC5 | -4673.0 |
| SHQ1 | -4648.0 |
| KIF2A | -4638.0 |
| TUBA1B | -4624.0 |
| PCNT | -4617.0 |
| POLR2J | -4576.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| H4C6 | -4534.0 |
| COP1 | -4515.0 |
| CDC25C | -4507.0 |
| CEP250 | -4503.0 |
| ESCO2 | -4488.0 |
| RAD1 | -4483.0 |
| CDK7 | -4467.0 |
| PPP6R3 | -4379.0 |
| RNF8 | -4361.0 |
| NUP85 | -4358.0 |
| RBL1 | -4357.0 |
| UBE2D1 | -4355.0 |
| XPO1 | -4345.0 |
| CLASP2 | -4343.0 |
| NUP98 | -4330.0 |
| PPP2R2A | -4274.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| GTSE1 | -4241.0 |
| H2BC17 | -4192.0 |
| CEP41 | -4178.0 |
| POLR2B | -4142.0 |
| RSF1 | -4128.0 |
| HSP90AB1 | -4117.0 |
| UBE2E1 | -4108.0 |
| WRN | -4104.0 |
| USO1 | -4080.0 |
| MYBL2 | -4072.0 |
| GINS1 | -4069.0 |
| RAD50 | -4035.0 |
| TUBA8 | -4032.0 |
| PSMD1 | -3979.0 |
| WAPL | -3947.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| H4C4 | -3867.0 |
| CENPA | -3845.0 |
| H2AJ | -3814.0 |
| CNTRL | -3781.0 |
| POLD1 | -3772.0 |
| PIF1 | -3739.0 |
| CEP76 | -3720.0 |
| KNTC1 | -3683.0 |
| ANAPC2 | -3617.0 |
| TERF2IP | -3592.0 |
| H2BC26 | -3582.0 |
| NDE1 | -3562.0 |
| DYNLL1 | -3550.0 |
| NUF2 | -3541.0 |
| STN1 | -3529.0 |
| SYNE2 | -3526.0 |
| NIPBL | -3507.0 |
| CDKN1C | -3498.0 |
| NUP133 | -3446.0 |
| CDC25B | -3439.0 |
| SPDL1 | -3370.0 |
| MAD1L1 | -3364.0 |
| AKAP9 | -3238.0 |
| ANAPC15 | -3203.0 |
| TYMS | -3192.0 |
| CDKN1A | -3164.0 |
| HUS1 | -3130.0 |
| PSMC4 | -3089.0 |
| RAD21 | -3080.0 |
| ZWILCH | -3078.0 |
| ORC5 | -3040.0 |
| LPIN1 | -2997.0 |
| CDT1 | -2991.0 |
| RCC2 | -2861.0 |
| NUP188 | -2837.0 |
| PSMB1 | -2799.0 |
| ITGB3BP | -2777.0 |
| CENPQ | -2767.0 |
| CEP70 | -2717.0 |
| PRIM2 | -2697.0 |
| GSK3B | -2665.0 |
| B9D2 | -2628.0 |
| LEMD3 | -2627.0 |
| RANGAP1 | -2606.0 |
| NUP205 | -2593.0 |
| PAFAH1B1 | -2571.0 |
| E2F3 | -2555.0 |
| GINS2 | -2543.0 |
| DMC1 | -2505.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| MCPH1 | -2431.0 |
| OIP5 | -2403.0 |
| NOP10 | -2370.0 |
| BIRC5 | -2354.0 |
| STAG3 | -2320.0 |
| CENPW | -2304.0 |
| CDK6 | -2302.0 |
| CCNH | -2298.0 |
| CDK1 | -2219.0 |
| LPIN3 | -2143.0 |
| SYCE2 | -2127.0 |
| PSMC6 | -2126.0 |
| BABAM1 | -2123.0 |
| DYNC1I1 | -2088.0 |
| CENPT | -2076.0 |
| PDS5B | -2067.0 |
| LPIN2 | -2033.0 |
| RAN | -2031.0 |
| HAUS6 | -2029.0 |
| CSNK2A2 | -2019.0 |
| CLSPN | -2005.0 |
| CEP290 | -2002.0 |
| MNAT1 | -1983.0 |
| KAT5 | -1955.0 |
| TUBGCP3 | -1900.0 |
| TUBA1A | -1819.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| CTC1 | -1773.0 |
| TMPO | -1743.0 |
| PPP1CB | -1732.0 |
| PSMB9 | -1684.0 |
| ATR | -1677.0 |
| MAX | -1655.0 |
| CHMP7 | -1636.0 |
| RUVBL2 | -1602.0 |
| LBR | -1592.0 |
| H2AC8 | -1573.0 |
| CDK5RAP2 | -1570.0 |
| KPNB1 | -1539.0 |
| CCP110 | -1489.0 |
| POLR2H | -1463.0 |
| PSMA3 | -1391.0 |
| TPX2 | -1344.0 |
| POLE3 | -1337.0 |
| POLD3 | -1246.0 |
| MSH5 | -1177.0 |
| PSME3 | -1153.0 |
| FKBPL | -1084.0 |
| SGO1 | -1080.0 |
| CDKN2C | -1068.0 |
| PRKCA | -1066.0 |
| RMI1 | -1065.0 |
| PDS5A | -1046.0 |
| H2BC8 | -1029.0 |
| ANAPC11 | -1014.0 |
| CDCA8 | -916.0 |
| AURKA | -876.0 |
| NCAPG | -857.0 |
| GMNN | -813.0 |
| SMC1B | -775.0 |
| ATRIP | -702.0 |
| MCM7 | -690.0 |
| MCM4 | -651.0 |
| SYNE1 | -642.0 |
| DBF4 | -610.0 |
| TNPO1 | -607.0 |
| NEK7 | -599.0 |
| NCAPH | -562.0 |
| ORC3 | -561.0 |
| CENPP | -551.0 |
| TP53 | -548.0 |
| POLR2C | -541.0 |
| RAD17 | -530.0 |
| YWHAE | -521.0 |
| NUP160 | -518.0 |
| PCBP4 | -493.0 |
| PSMA1 | -477.0 |
| HMMR | -476.0 |
| E2F5 | -435.0 |
| LIN37 | -421.0 |
| H2AZ2 | -340.0 |
| DCTN1 | -338.0 |
| WEE1 | -335.0 |
| DSN1 | -331.0 |
| TUBGCP2 | -268.0 |
| SKP1 | -264.0 |
| PSMB8 | -260.0 |
| SYCP1 | -201.0 |
| NEK2 | -182.0 |
| CKS1B | -174.0 |
| UBA52 | -167.0 |
| STAG1 | -147.0 |
| MDC1 | -145.0 |
| H3-3B | -135.0 |
| POLR2L | -110.0 |
| AHCTF1 | -75.0 |
| KIF2B | -57.0 |
| PCNA | -40.0 |
| DNA2 | -36.0 |
| RFC3 | -16.0 |
| CEP78 | 13.0 |
| MAPK1 | 78.0 |
| MDM4 | 110.0 |
| YWHAG | 115.0 |
| IST1 | 123.0 |
| NPM1 | 252.0 |
| LIN52 | 259.0 |
| TUBB | 261.0 |
| SKA2 | 265.0 |
| RBL2 | 314.0 |
| NUP37 | 339.0 |
| BUB1B | 349.0 |
| ANKRD28 | 363.0 |
| PSMB10 | 447.0 |
| VRK2 | 465.0 |
| POT1 | 546.0 |
| EML4 | 552.0 |
| OPTN | 580.0 |
| BUB1 | 660.0 |
| RAB1B | 777.0 |
| NEDD1 | 779.0 |
| SMC4 | 787.0 |
| NSL1 | 804.0 |
| MYC | 805.0 |
| BANF1 | 835.0 |
| CENPS | 874.0 |
| H4C5 | 878.0 |
| ENSA | 893.0 |
| PSMD12 | 901.0 |
| RAD51 | 905.0 |
| MCM8 | 954.0 |
| SEC13 | 959.0 |
| KIF18A | 960.0 |
| HAUS3 | 961.0 |
| RFC4 | 973.0 |
| NME7 | 1011.0 |
| CENPJ | 1016.0 |
| BABAM2 | 1018.0 |
| CDC16 | 1047.0 |
| TUBB1 | 1069.0 |
| PRIM1 | 1073.0 |
| KIF20A | 1088.0 |
| DHFR | 1150.0 |
| SMC3 | 1172.0 |
| MIS18BP1 | 1206.0 |
| RPA2 | 1210.0 |
| PSMD14 | 1213.0 |
| FZR1 | 1228.0 |
| CSNK1E | 1281.0 |
| CENPM | 1294.0 |
| GAR1 | 1307.0 |
| SPC25 | 1348.0 |
| PPME1 | 1452.0 |
| PPP2R5A | 1480.0 |
| RCC1 | 1490.0 |
| CSNK1D | 1496.0 |
| WRAP53 | 1601.0 |
| POLR2E | 1649.0 |
| NUP62 | 1710.0 |
| PPP6C | 1738.0 |
| SEM1 | 1794.0 |
| PHLDA1 | 1804.0 |
| RPS27A | 1846.0 |
| ORC4 | 1871.0 |
| TERF2 | 1872.0 |
| CENPN | 1892.0 |
| MIS12 | 1902.0 |
| CTDNEP1 | 1909.0 |
| H2BC3 | 1920.0 |
| CSNK2A1 | 2040.0 |
| SUMO1 | 2052.0 |
| SSNA1 | 2103.0 |
| MCM3 | 2165.0 |
| PSMC5 | 2183.0 |
| RAE1 | 2192.0 |
| FBXL7 | 2214.0 |
| ACTR1A | 2220.0 |
| PSMD8 | 2235.0 |
| CENPE | 2236.0 |
| CABLES1 | 2267.0 |
| SFI1 | 2352.0 |
| RAD51C | 2354.0 |
| EXO1 | 2396.0 |
| PPP2R5C | 2434.0 |
| MAPK3 | 2444.0 |
| GINS4 | 2507.0 |
| MAPRE1 | 2575.0 |
| CDC45 | 2747.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| ALMS1 | 2804.0 |
| NDC1 | 2860.0 |
| E2F1 | 2922.0 |
| FEN1 | 2933.0 |
| MLH1 | 3003.0 |
| RANBP2 | 3016.0 |
| BRIP1 | 3028.0 |
| RAB8A | 3057.0 |
| TP53BP1 | 3107.0 |
| TUBA3C | 3214.0 |
| RTEL1 | 3221.0 |
| SKA1 | 3245.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| RMI2 | 3423.0 |
| NUDC | 3440.0 |
| UIMC1 | 3452.0 |
| CENPK | 3476.0 |
| NBN | 3478.0 |
| NEK9 | 3481.0 |
| CENPL | 3515.0 |
| TUBB6 | 3539.0 |
| CEP57 | 3574.0 |
| PLK4 | 3579.0 |
| CDC26 | 3611.0 |
| TUBB4A | 3612.0 |
| TERT | 3617.0 |
| FBXL18 | 3661.0 |
| PIAS4 | 3685.0 |
| PPP1R12B | 3710.0 |
| MND1 | 3851.0 |
| BLM | 3894.0 |
| PSMC3IP | 3904.0 |
| H3C2 | 3915.0 |
| MCM5 | 3943.0 |
| NUP153 | 4025.0 |
| PRKAR2B | 4071.0 |
| NUP54 | 4170.0 |
| POLA2 | 4192.0 |
| FBXO5 | 4212.0 |
| CCND2 | 4231.0 |
| PPP2R5B | 4232.0 |
| AAAS | 4254.0 |
| CCNE2 | 4280.0 |
| CCND1 | 4294.0 |
| RFC2 | 4313.0 |
| CCND3 | 4317.0 |
| H3-3A | 4335.0 |
| ACD | 4346.5 |
| SUN2 | 4348.0 |
| CCNA2 | 4366.0 |
| RBBP4 | 4375.0 |
| PMF1 | 4398.0 |
| CUL1 | 4399.0 |
| HSP90AA1 | 4414.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| RPA3 | 4481.0 |
| PKMYT1 | 4486.0 |
| HAUS2 | 4581.0 |
| FKBP6 | 4602.0 |
| CDK4 | 4604.0 |
| RAB1A | 4669.0 |
| MCM2 | 4670.0 |
| AKT1 | 4674.0 |
| CDCA5 | 4721.0 |
| SKP2 | 4760.0 |
| HAUS4 | 4825.0 |
| POLR2I | 4862.0 |
| AURKB | 4877.0 |
| UBE2N | 4905.0 |
| PSMB4 | 4971.0 |
| SPC24 | 5022.0 |
| NEK6 | 5041.0 |
| H4C3 | 5053.0 |
| LMNA | 5119.0 |
| ESCO1 | 5153.0 |
| CDK2 | 5165.0 |
| PSMF1 | 5221.0 |
| KMT5A | 5304.0 |
| PSMD7 | 5305.0 |
| HAUS1 | 5311.0 |
| NUP58 | 5365.0 |
| TAOK1 | 5424.0 |
| UBE2S | 5479.0 |
| MRE11 | 5531.0 |
| DAXX | 5566.0 |
| NHP2 | 5624.0 |
| SEH1L | 5647.0 |
| RPS27 | 5679.0 |
| YWHAZ | 5701.0 |
| MDM2 | 5757.0 |
| RAD9A | 5759.0 |
| PSMB2 | 5803.0 |
| TUBG1 | 5806.0 |
| CEP135 | 5819.0 |
| FBXW11 | 5855.0 |
| PSMB7 | 5858.0 |
| SPO11 | 5863.0 |
| H3C3 | 5902.0 |
| TEX12 | 5932.0 |
| TEN1 | 5990.0 |
| H3C1 | 6001.0 |
| POLD4 | 6046.0 |
| NDC80 | 6086.0 |
| PRKACA | 6168.0 |
| MASTL | 6217.0 |
| TUBB3 | 6221.0 |
| DCTN2 | 6256.0 |
| HAUS8 | 6365.0 |
| ARPP19 | 6373.0 |
| CHTF18 | 6413.0 |
| H2BC11 | 6454.0 |
| PRDM9 | 6466.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| KNL1 | 6545.0 |
| SRC | 6605.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| MZT2B | 6651.0 |
| UBC | 6700.0 |
| E2F4 | 6720.0 |
| PPP2R5D | 6733.0 |
| SYCE3 | 6824.0 |
| DYNC1LI1 | 6830.0 |
| RAD9B | 6859.0 |
| H2AC4 | 6905.0 |
| CENPU | 6916.0 |
| PSMA6 | 6984.0 |
| UBE2I | 7189.0 |
| CDC20 | 7234.0 |
| CHMP6 | 7265.0 |
| H2BC21 | 7408.0 |
| NUP155 | 7411.0 |
| CHEK2 | 7446.0 |
| CCNE1 | 7482.0 |
| SYCE1 | 7498.0 |
| CDKN2B | 7557.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| BUB3 | 7623.0 |
| YWHAH | 7669.0 |
| H2BC12 | 7676.0 |
| PSMB3 | 8017.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| POLR2D | 8323.0 |
| LYN | 8377.0 |
| POLE4 | 8577.0 |
| TK1 | 8605.0 |
| ZNF385A | 8625.0 |
| SET | 8685.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| POLR2F | 8864.0 |
| H2AZ1 | 8917.0 |
| LIG1 | 8960.0 |
| KIF23 | 8961.0 |
| POLR2G | 9208.0 |
| H2AC14 | 9376.0 |
| CDKN2D | 9489.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| NINL | 9656.0 |
| PSME1 | 9765.0 |
| H4C12 | 10027.0 |
| ANAPC1 | 10085.0 |
| H2BC14 | 10168.0 |
| RBX1 | 10301.0 |
| SFN | 10357.0 |
| PTK6 | 10895.0 |
| TEX15 | 10936.0 |
| TUBB8 | 11325.0 |
REACTOME_OLFACTORY_SIGNALING_PATHWAY
| 628 | |
|---|---|
| set | REACTOME_OLFACTORY_SIGNALING_PATHWAY |
| setSize | 348 |
| pANOVA | 2.3e-12 |
| s.dist | 0.219 |
| p.adjustANOVA | 9.44e-10 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| OR6Q1 | 11526 |
| OR2T3 | 11520 |
| OR2V1 | 11508 |
| OR8A1 | 11481 |
| OR5M10 | 11436 |
| OR8U3 | 11430 |
| OR4C12 | 11429 |
| OR2S2 | 11382 |
| OR1K1 | 11368 |
| OR2M7 | 11362 |
| OR2AG1 | 11346 |
| OR4A47 | 11331 |
| OR2L5 | 11292 |
| OR51F1 | 11264 |
| OR56B4 | 11197 |
| OR1N2 | 11196 |
| OR2L3 | 11182 |
| OR2A5 | 11152 |
| OR1N1 | 11114 |
| OR10P1 | 11095 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| OR6Q1 | 11526.0 |
| OR2T3 | 11520.0 |
| OR2V1 | 11508.0 |
| OR8A1 | 11481.0 |
| OR5M10 | 11436.0 |
| OR8U3 | 11430.0 |
| OR4C12 | 11429.0 |
| OR2S2 | 11382.0 |
| OR1K1 | 11368.0 |
| OR2M7 | 11362.0 |
| OR2AG1 | 11346.0 |
| OR4A47 | 11331.0 |
| OR2L5 | 11292.0 |
| OR51F1 | 11264.0 |
| OR56B4 | 11197.0 |
| OR1N2 | 11196.0 |
| OR2L3 | 11182.0 |
| OR2A5 | 11152.0 |
| OR1N1 | 11114.0 |
| OR10P1 | 11095.0 |
| OR2AK2 | 11078.0 |
| OR5A2 | 11069.0 |
| OR6C65 | 11067.0 |
| OR2L2 | 11028.0 |
| OR51G2 | 11014.0 |
| OR10J1 | 11011.0 |
| CNGA4 | 10986.0 |
| OR10Z1 | 10968.0 |
| OR6C4 | 10956.0 |
| OR5T3 | 10949.0 |
| OR5D13 | 10935.0 |
| OR2M5 | 10922.0 |
| OR51G1 | 10885.0 |
| OR10AG1 | 10878.0 |
| OR5H2 | 10875.0 |
| OR56B1 | 10834.0 |
| OR4C3 | 10810.0 |
| OR51A7 | 10807.0 |
| OR4N5 | 10802.0 |
| OR51S1 | 10800.0 |
| OR2T27 | 10759.0 |
| OR4C15 | 10744.0 |
| OR5L1 | 10741.0 |
| OR1E2 | 10728.0 |
| OR5T2 | 10725.0 |
| OR6B2 | 10719.0 |
| OR4B1 | 10709.0 |
| OR10G9 | 10685.0 |
| OR1S2 | 10668.0 |
| OR4N2 | 10667.0 |
| OR5H6 | 10631.0 |
| OR10A7 | 10623.0 |
| OR8G5 | 10583.0 |
| OR2H2 | 10546.0 |
| OR6C2 | 10535.0 |
| OR2T6 | 10532.0 |
| OR7D4 | 10513.0 |
| OR2D2 | 10496.0 |
| OR8G1 | 10492.0 |
| OR5A1 | 10488.0 |
| OR8B12 | 10477.0 |
| OR2K2 | 10440.0 |
| OR5L2 | 10439.0 |
| OR8D4 | 10419.0 |
| OR2T12 | 10344.0 |
| OR10T2 | 10343.0 |
| OR5P2 | 10306.0 |
| OR6C74 | 10273.0 |
| OR6B1 | 10264.0 |
| OR8I2 | 10228.0 |
| OR5M1 | 10192.0 |
| OR2M2 | 10157.0 |
| OR52A1 | 10153.0 |
| OR13C4 | 10131.0 |
| OR10S1 | 10114.0 |
| OR6C1 | 10077.0 |
| OR5V1 | 9989.0 |
| OR8S1 | 9966.0 |
| OR4K15 | 9959.0 |
| OR4D6 | 9858.0 |
| OR2Y1 | 9855.0 |
| OR1J4 | 9837.0 |
| OR10G3 | 9831.0 |
| OR4K13 | 9754.0 |
| OR6A2 | 9751.0 |
| OR51F2 | 9730.0 |
| OR1F1 | 9694.0 |
| OR1G1 | 9651.0 |
| OR5H15 | 9636.0 |
| OR4M1 | 9625.0 |
| OR8K5 | 9620.0 |
| OR4X1 | 9589.0 |
| OR4K2 | 9582.0 |
| OR52N2 | 9556.0 |
| OR8D2 | 9530.0 |
| OR4F6 | 9496.0 |
| OR2L8 | 9473.0 |
| OR2M3 | 9448.0 |
| GNG13 | 9443.0 |
| OR10G4 | 9407.0 |
| OR8B8 | 9351.0 |
| OR5M3 | 9325.0 |
| OR2H1 | 9219.0 |
| OR5I1 | 9206.0 |
| OR10W1 | 9113.0 |
| OR9G1 | 9104.5 |
| OR9G9 | 9104.5 |
| OR10A4 | 9087.0 |
| OR2A2 | 9077.0 |
| OR7C1 | 9075.0 |
| OR4A16 | 9052.0 |
| OR4D9 | 9004.0 |
| OR13A1 | 8896.0 |
| OR51B4 | 8882.0 |
| OR9Q2 | 8850.0 |
| OR51V1 | 8753.0 |
| OR4D11 | 8663.0 |
| OR1J2 | 8637.0 |
| OR56A1 | 8572.0 |
| OR2T33 | 8542.0 |
| OR1E1 | 8503.0 |
| OR52A5 | 8500.0 |
| OR7A5 | 8482.0 |
| OR51B2 | 8469.0 |
| OR13F1 | 8467.0 |
| OR12D3 | 8407.0 |
| OR8U8 | 8388.0 |
| EBF1 | 8381.0 |
| RTP2 | 8322.0 |
| OR1A2 | 8296.0 |
| ANO2 | 8254.0 |
| OR51B5 | 8064.0 |
| OR2L13 | 8041.0 |
| OR6S1 | 8002.0 |
| OR2W3 | 8000.0 |
| OR2T4 | 7973.0 |
| OR51M1 | 7857.0 |
| OR12D2 | 7718.0 |
| OR11A1 | 7637.0 |
| OR10H3 | 7607.0 |
| OR11H6 | 7574.0 |
| OR10K2 | 7424.0 |
| OR10C1 | 7405.0 |
| OR4C46 | 7380.0 |
| OR9G4 | 7332.0 |
| OR10H2 | 7308.0 |
| OR2T11 | 7206.0 |
| OR1B1 | 7199.0 |
| OR5T1 | 7198.0 |
| OR5B3 | 7194.0 |
| OR2W1 | 7059.0 |
| OR1C1 | 7020.0 |
| OR13C9 | 6996.0 |
| OR8K1 | 6953.0 |
| OR6X1 | 6942.0 |
| OR10A2 | 6809.0 |
| OR5AR1 | 6703.0 |
| OR13C2 | 6695.0 |
| OR4K17 | 6618.0 |
| CNGB1 | 6587.0 |
| OR51D1 | 6577.0 |
| OR2F1 | 6574.0 |
| OR9A4 | 6452.0 |
| OR2B3 | 6432.0 |
| OR8U1 | 6414.0 |
| OR52E2 | 6360.0 |
| OR4S1 | 6347.0 |
| OR10H5 | 6166.0 |
| OR10J5 | 6146.0 |
| OR6C3 | 6126.0 |
| OR2G6 | 6072.0 |
| OR14J1 | 6051.0 |
| OR2AP1 | 6040.0 |
| OR52B6 | 6019.0 |
| OR9Q1 | 5976.0 |
| RTP1 | 5708.0 |
| OR4D1 | 5633.0 |
| OR5W2 | 5572.0 |
| OR56A4 | 5518.0 |
| OR10G2 | 5461.0 |
| OR2D3 | 5407.0 |
| OR6B3 | 4879.0 |
| OR5D16 | 4868.0 |
| OR51E2 | 4861.0 |
| OR10K1 | 4826.0 |
| OR13C8 | 4812.0 |
| OR10V1 | 4788.0 |
| OR2F2 | 4517.0 |
| OR5D14 | 4508.0 |
| LDB1 | 4278.0 |
| OR5J2 | 4161.0 |
| OR6N2 | 3985.0 |
| OR52E4 | 3984.0 |
| OR51B6 | 3980.0 |
| OR5K4 | 3891.0 |
| OR5B12 | 3863.0 |
| OR4A15 | 3837.0 |
| OR4L1 | 3819.0 |
| OR14I1 | 3625.0 |
| OR7G3 | 3544.0 |
| OR4X2 | 3542.0 |
| OR10A6 | 3165.0 |
| OR9K2 | 3046.0 |
| OR1A1 | 2995.0 |
| OR5F1 | 2902.0 |
| OR3A3 | 2786.0 |
| OR6C70 | 2754.0 |
| ADCY3 | 2673.0 |
| REEP1 | 2357.0 |
| OR52K2 | 2114.0 |
| OR51E1 | 2044.0 |
| OR52M1 | 2024.0 |
| OR2B11 | 1916.0 |
| OR52D1 | 1878.0 |
| OR5B2 | 1870.0 |
| OR10H1 | 1841.0 |
| OR51Q1 | 1807.0 |
| OR2T8 | 1660.0 |
| OR2AT4 | 1558.0 |
| OR4K14 | 1544.0 |
| OR1L1 | 1423.0 |
| OR4K5 | 1007.0 |
| OR7C2 | 848.0 |
| OR6K2 | 764.0 |
| OR1L3 | 704.0 |
| OR52N1 | 676.0 |
| OR11G2 | 427.0 |
| OR13C3 | 317.0 |
| GNAL | 213.0 |
| OR51I1 | 187.0 |
| OR52B2 | 68.0 |
| OR8B2 | -5.0 |
| OR5D18 | -73.0 |
| OR2B6 | -249.0 |
| OR5AS1 | -259.0 |
| OR3A2 | -280.0 |
| OR5B17 | -490.0 |
| OR51L1 | -975.0 |
| OR4F15 | -982.0 |
| OR7A17 | -1468.0 |
| OR10G7 | -1753.0 |
| OR10J3 | -1888.0 |
| OR13D1 | -2074.0 |
| OR52I2 | -2150.0 |
| OR10A5 | -2168.0 |
| OR10H4 | -2234.0 |
| OR7G1 | -2296.0 |
| OR2A12 | -2425.0 |
| OR13J1 | -2493.0 |
| OR5AU1 | -2805.0 |
| OR1D2 | -2814.0 |
| GNB1 | -3044.0 |
| OR4A5 | -3180.0 |
| OR6K3 | -3182.0 |
| OR6K6 | -3230.0 |
| OR5C1 | -3300.0 |
| OR8J1 | -3357.0 |
| OR6C75 | -3482.0 |
| OR9I1 | -4242.0 |
| OR8J3 | -4284.0 |
| OR5AN1 | -4684.0 |
| OR5M11 | -4694.0 |
| OR14C36 | -4698.0 |
| OR5B21 | -4841.0 |
| OR5K1 | -4952.0 |
| OR13G1 | -5061.0 |
| OR6Y1 | -5211.0 |
| OR56A3 | -5392.0 |
| OR9A2 | -5558.0 |
| OR10G8 | -6149.0 |
| OR10Q1 | -6168.0 |
| OR5M9 | -6221.0 |
| OR4E2 | -6347.0 |
| OR4D2 | -6446.0 |
| OR51I2 | -6462.0 |
| OR52W1 | -6539.0 |
| OR51T1 | -6576.0 |
| OR4D10 | -6638.0 |
| OR1M1 | -6663.0 |
| OR5AP2 | -6823.0 |
| OR10X1 | -6889.0 |
| OR4K1 | -6988.0 |
| OR2M4 | -7001.0 |
| OR1L6 | -7242.0 |
| OR2G2 | -7259.0 |
| OR2C1 | -7329.0 |
| OR52R1 | -7469.0 |
| OR6V1 | -7514.0 |
| OR1I1 | -7610.0 |
| OR5P3 | -7653.0 |
| OR7D2 | -7744.0 |
| OR2Z1 | -7772.0 |
| OR8B4 | -7909.0 |
| OR52H1 | -7934.0 |
| OR4C6 | -8001.0 |
| OR8K3 | -8006.0 |
| OR52E8 | -8076.0 |
| OR6F1 | -8092.0 |
| OR52I1 | -8148.0 |
| OR5AK2 | -8345.0 |
| OR2V2 | -8375.0 |
| OR2B2 | -8425.0 |
| OR6N1 | -8451.0 |
| OR10A3 | -8505.0 |
| OR2G3 | -8522.0 |
| OR2J2 | -8617.0 |
| OR5K2 | -8686.0 |
| OR7A10 | -8699.0 |
| OR6M1 | -8844.0 |
| OR2A14 | -8899.0 |
| OR1L8 | -8972.0 |
| OR3A1 | -8985.0 |
| OR1S1 | -9151.0 |
| OR4C45 | -9179.0 |
| OR5M8 | -9205.0 |
| OR2C3 | -9237.0 |
| OR6T1 | -9317.0 |
| OR1Q1 | -9338.0 |
| OR11H4 | -9369.0 |
| OR6P1 | -9375.0 |
| LHX2 | -9462.0 |
| OR6C68 | -9469.0 |
| OR2AE1 | -9559.0 |
| OR52J3 | -9657.0 |
| OR7G2 | -9698.0 |
| OR11L1 | -9725.0 |
| OR51A2 | -9729.0 |
| OR1J1 | -9739.0 |
| OR6C76 | -9740.0 |
| OR52L1 | -9752.0 |
| OR7E24 | -9826.0 |
| OR56A5 | -9853.0 |
| OR6C6 | -9860.0 |
| OR8H1 | -9867.0 |
| OR5AC2 | -9882.0 |
| OR1L4 | -9883.0 |
| OR2AG2 | -9932.0 |
| OR8D1 | -9966.0 |
| OR52E6 | -9980.0 |
| OR4C16 | -10005.0 |
| OR2T1 | -10139.0 |
| OR52K1 | -10237.0 |
| OR4D5 | -10252.0 |
| OR10AD1 | -10274.0 |
| OR8H3 | -10391.0 |
| OR14A16 | -10393.0 |
| OR5K3 | -10407.0 |
| OR5H1 | -10415.0 |
REACTOME_CELL_CYCLE_MITOTIC
| 1112 | |
|---|---|
| set | REACTOME_CELL_CYCLE_MITOTIC |
| setSize | 539 |
| pANOVA | 4.66e-11 |
| s.dist | -0.166 |
| p.adjustANOVA | 1.53e-08 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| CC2D1B | -9830.0 |
| CDK11A | -9721.0 |
| CHMP2B | -9643.0 |
| FOXM1 | -9614.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| CDC14A | -9420.0 |
| GOLGA2 | -9392.0 |
| HDAC1 | -9320.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
| TFDP1 | -9109.0 |
| POM121C | -9098.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| CC2D1B | -9830.0 |
| CDK11A | -9721.0 |
| CHMP2B | -9643.0 |
| FOXM1 | -9614.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| CDC14A | -9420.0 |
| GOLGA2 | -9392.0 |
| HDAC1 | -9320.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
| TFDP1 | -9109.0 |
| POM121C | -9098.0 |
| TUBB4B | -9023.0 |
| TOP2A | -9001.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| LEMD2 | -8856.0 |
| VPS4A | -8736.0 |
| RB1 | -8714.0 |
| RAB2A | -8702.0 |
| TUBA1C | -8675.0 |
| ANAPC5 | -8661.0 |
| CENPH | -8616.0 |
| LIN9 | -8611.0 |
| H4C13 | -8603.0 |
| PSMB11 | -8512.0 |
| TUBG2 | -8420.0 |
| NCAPD2 | -8303.0 |
| TUBA3E | -8293.0 |
| POM121 | -8267.0 |
| CEP192 | -8256.0 |
| MZT2A | -8243.0 |
| H2BC13 | -8199.0 |
| MCM6 | -8182.0 |
| H4C16 | -8109.0 |
| NDEL1 | -8074.0 |
| CDC6 | -8067.0 |
| MZT1 | -8047.0 |
| PSMC1 | -7848.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| BORA | -7784.0 |
| CHMP4C | -7757.0 |
| RPA1 | -7755.0 |
| POLE | -7738.0 |
| MAU2 | -7729.0 |
| CEP164 | -7722.0 |
| BLZF1 | -7718.0 |
| CENPO | -7707.0 |
| CDK11B | -7666.0 |
| H2AX | -7648.0 |
| RRM2 | -7580.0 |
| CKAP5 | -7526.0 |
| GORASP2 | -7497.0 |
| PPP2R2D | -7485.0 |
| DYNLL2 | -7477.0 |
| POLE2 | -7447.0 |
| ZWINT | -7442.0 |
| GINS3 | -7376.0 |
| H3C6 | -7372.0 |
| PSMD13 | -7362.0 |
| BTRC | -7343.0 |
| KIF2C | -7337.0 |
| GORASP1 | -7335.0 |
| ORC2 | -7207.0 |
| NUP214 | -7186.0 |
| PTTG1 | -7163.0 |
| CHMP4B | -7159.0 |
| NCAPH2 | -7155.0 |
| MCM10 | -7149.0 |
| EP300 | -7126.0 |
| SPAST | -7098.0 |
| POLD2 | -7092.0 |
| ODF2 | -7061.0 |
| NCAPG2 | -7020.0 |
| CDKN1B | -6954.0 |
| CCNB2 | -6945.0 |
| NUMA1 | -6884.0 |
| ABL1 | -6881.0 |
| CENPC | -6867.0 |
| NUP88 | -6865.0 |
| LCMT1 | -6864.0 |
| CDC7 | -6856.0 |
| ANKLE2 | -6706.0 |
| NCAPD3 | -6668.0 |
| RFC1 | -6662.0 |
| CDC25A | -6647.0 |
| PLK1 | -6633.0 |
| PPP1CC | -6627.0 |
| TUBA4A | -6626.0 |
| PSMD3 | -6608.0 |
| SMC2 | -6571.0 |
| DCTN3 | -6556.0 |
| NUP42 | -6551.0 |
| H2BC10 | -6510.0 |
| PCM1 | -6483.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| CEP152 | -6444.0 |
| PSMD4 | -6409.0 |
| CEP131 | -6383.0 |
| E2F6 | -6358.0 |
| PSMB5 | -6339.0 |
| TUBB2B | -6314.0 |
| LIN54 | -6191.0 |
| ORC6 | -6177.0 |
| CEP72 | -6174.0 |
| CENPF | -6110.0 |
| CSNK2B | -6080.0 |
| ZW10 | -6072.0 |
| MAD2L1 | -6059.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| HAUS5 | -6025.0 |
| TUBB2A | -5979.0 |
| ESPL1 | -5959.0 |
| NUP210 | -5812.0 |
| TUBGCP5 | -5800.0 |
| ANAPC7 | -5789.0 |
| H2AC6 | -5775.0 |
| CLIP1 | -5755.0 |
| H2BC15 | -5694.0 |
| AKT3 | -5680.0 |
| TUBGCP6 | -5669.0 |
| LMNB1 | -5639.0 |
| H3C11 | -5538.0 |
| TPR | -5490.0 |
| SIRT2 | -5451.0 |
| H3-4 | -5447.0 |
| AKT2 | -5419.0 |
| ORC1 | -5405.0 |
| CLASP1 | -5346.0 |
| JAK2 | -5312.0 |
| H2BC6 | -5295.0 |
| PSMC3 | -5262.0 |
| PPP1R12A | -5243.0 |
| CNEP1R1 | -5168.0 |
| PPP2R5E | -5142.0 |
| DYNC1I2 | -5131.0 |
| CHMP2A | -5098.0 |
| CEP63 | -5092.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| E2F2 | -5059.0 |
| PSME4 | -5053.0 |
| TUBAL3 | -5043.0 |
| TUBA4B | -5020.0 |
| CEP43 | -4973.0 |
| DYRK1A | -4936.0 |
| AJUBA | -4908.0 |
| PRKCB | -4898.0 |
| PSMA5 | -4888.0 |
| CHMP3 | -4842.0 |
| CDC23 | -4806.0 |
| TFDP2 | -4787.0 |
| CDC27 | -4761.0 |
| SDCCAG8 | -4735.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| CDKN2A | -4700.0 |
| RFC5 | -4673.0 |
| KIF2A | -4638.0 |
| TUBA1B | -4624.0 |
| PCNT | -4617.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| H4C6 | -4534.0 |
| CDC25C | -4507.0 |
| CEP250 | -4503.0 |
| ESCO2 | -4488.0 |
| CDK7 | -4467.0 |
| NUP85 | -4358.0 |
| RBL1 | -4357.0 |
| UBE2D1 | -4355.0 |
| XPO1 | -4345.0 |
| CLASP2 | -4343.0 |
| NUP98 | -4330.0 |
| PPP2R2A | -4274.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| GTSE1 | -4241.0 |
| H2BC17 | -4192.0 |
| CEP41 | -4178.0 |
| HSP90AB1 | -4117.0 |
| UBE2E1 | -4108.0 |
| USO1 | -4080.0 |
| MYBL2 | -4072.0 |
| GINS1 | -4069.0 |
| TUBA8 | -4032.0 |
| PSMD1 | -3979.0 |
| WAPL | -3947.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| H4C4 | -3867.0 |
| CENPA | -3845.0 |
| H2AJ | -3814.0 |
| CNTRL | -3781.0 |
| POLD1 | -3772.0 |
| CEP76 | -3720.0 |
| KNTC1 | -3683.0 |
| ANAPC2 | -3617.0 |
| H2BC26 | -3582.0 |
| NDE1 | -3562.0 |
| DYNLL1 | -3550.0 |
| NUF2 | -3541.0 |
| NIPBL | -3507.0 |
| CDKN1C | -3498.0 |
| NUP133 | -3446.0 |
| CDC25B | -3439.0 |
| SPDL1 | -3370.0 |
| MAD1L1 | -3364.0 |
| AKAP9 | -3238.0 |
| ANAPC15 | -3203.0 |
| TYMS | -3192.0 |
| CDKN1A | -3164.0 |
| PSMC4 | -3089.0 |
| RAD21 | -3080.0 |
| ZWILCH | -3078.0 |
| ORC5 | -3040.0 |
| LPIN1 | -2997.0 |
| CDT1 | -2991.0 |
| RCC2 | -2861.0 |
| NUP188 | -2837.0 |
| PSMB1 | -2799.0 |
| ITGB3BP | -2777.0 |
| CENPQ | -2767.0 |
| CEP70 | -2717.0 |
| PRIM2 | -2697.0 |
| GSK3B | -2665.0 |
| B9D2 | -2628.0 |
| LEMD3 | -2627.0 |
| RANGAP1 | -2606.0 |
| NUP205 | -2593.0 |
| PAFAH1B1 | -2571.0 |
| E2F3 | -2555.0 |
| GINS2 | -2543.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| MCPH1 | -2431.0 |
| BIRC5 | -2354.0 |
| CDK6 | -2302.0 |
| CCNH | -2298.0 |
| CDK1 | -2219.0 |
| LPIN3 | -2143.0 |
| PSMC6 | -2126.0 |
| DYNC1I1 | -2088.0 |
| CENPT | -2076.0 |
| PDS5B | -2067.0 |
| LPIN2 | -2033.0 |
| RAN | -2031.0 |
| HAUS6 | -2029.0 |
| CSNK2A2 | -2019.0 |
| CEP290 | -2002.0 |
| MNAT1 | -1983.0 |
| TUBGCP3 | -1900.0 |
| TUBA1A | -1819.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| TMPO | -1743.0 |
| PPP1CB | -1732.0 |
| PSMB9 | -1684.0 |
| MAX | -1655.0 |
| CHMP7 | -1636.0 |
| LBR | -1592.0 |
| H2AC8 | -1573.0 |
| CDK5RAP2 | -1570.0 |
| KPNB1 | -1539.0 |
| CCP110 | -1489.0 |
| PSMA3 | -1391.0 |
| TPX2 | -1344.0 |
| POLE3 | -1337.0 |
| POLD3 | -1246.0 |
| PSME3 | -1153.0 |
| FKBPL | -1084.0 |
| SGO1 | -1080.0 |
| CDKN2C | -1068.0 |
| PRKCA | -1066.0 |
| PDS5A | -1046.0 |
| H2BC8 | -1029.0 |
| ANAPC11 | -1014.0 |
| CDCA8 | -916.0 |
| AURKA | -876.0 |
| NCAPG | -857.0 |
| GMNN | -813.0 |
| MCM7 | -690.0 |
| MCM4 | -651.0 |
| DBF4 | -610.0 |
| TNPO1 | -607.0 |
| NEK7 | -599.0 |
| NCAPH | -562.0 |
| ORC3 | -561.0 |
| CENPP | -551.0 |
| TP53 | -548.0 |
| YWHAE | -521.0 |
| NUP160 | -518.0 |
| PSMA1 | -477.0 |
| HMMR | -476.0 |
| E2F5 | -435.0 |
| LIN37 | -421.0 |
| H2AZ2 | -340.0 |
| DCTN1 | -338.0 |
| WEE1 | -335.0 |
| DSN1 | -331.0 |
| TUBGCP2 | -268.0 |
| SKP1 | -264.0 |
| PSMB8 | -260.0 |
| NEK2 | -182.0 |
| CKS1B | -174.0 |
| UBA52 | -167.0 |
| STAG1 | -147.0 |
| H3-3B | -135.0 |
| AHCTF1 | -75.0 |
| KIF2B | -57.0 |
| PCNA | -40.0 |
| DNA2 | -36.0 |
| RFC3 | -16.0 |
| CEP78 | 13.0 |
| MAPK1 | 78.0 |
| YWHAG | 115.0 |
| IST1 | 123.0 |
| LIN52 | 259.0 |
| TUBB | 261.0 |
| SKA2 | 265.0 |
| RBL2 | 314.0 |
| NUP37 | 339.0 |
| BUB1B | 349.0 |
| PSMB10 | 447.0 |
| VRK2 | 465.0 |
| EML4 | 552.0 |
| OPTN | 580.0 |
| BUB1 | 660.0 |
| RAB1B | 777.0 |
| NEDD1 | 779.0 |
| SMC4 | 787.0 |
| NSL1 | 804.0 |
| MYC | 805.0 |
| BANF1 | 835.0 |
| CENPS | 874.0 |
| H4C5 | 878.0 |
| ENSA | 893.0 |
| PSMD12 | 901.0 |
| MCM8 | 954.0 |
| SEC13 | 959.0 |
| KIF18A | 960.0 |
| HAUS3 | 961.0 |
| RFC4 | 973.0 |
| NME7 | 1011.0 |
| CENPJ | 1016.0 |
| CDC16 | 1047.0 |
| TUBB1 | 1069.0 |
| PRIM1 | 1073.0 |
| KIF20A | 1088.0 |
| DHFR | 1150.0 |
| SMC3 | 1172.0 |
| RPA2 | 1210.0 |
| PSMD14 | 1213.0 |
| FZR1 | 1228.0 |
| CSNK1E | 1281.0 |
| CENPM | 1294.0 |
| SPC25 | 1348.0 |
| PPME1 | 1452.0 |
| PPP2R5A | 1480.0 |
| RCC1 | 1490.0 |
| CSNK1D | 1496.0 |
| NUP62 | 1710.0 |
| SEM1 | 1794.0 |
| PHLDA1 | 1804.0 |
| RPS27A | 1846.0 |
| ORC4 | 1871.0 |
| CENPN | 1892.0 |
| MIS12 | 1902.0 |
| CTDNEP1 | 1909.0 |
| H2BC3 | 1920.0 |
| CSNK2A1 | 2040.0 |
| SUMO1 | 2052.0 |
| SSNA1 | 2103.0 |
| MCM3 | 2165.0 |
| PSMC5 | 2183.0 |
| RAE1 | 2192.0 |
| FBXL7 | 2214.0 |
| ACTR1A | 2220.0 |
| PSMD8 | 2235.0 |
| CENPE | 2236.0 |
| CABLES1 | 2267.0 |
| SFI1 | 2352.0 |
| PPP2R5C | 2434.0 |
| MAPK3 | 2444.0 |
| GINS4 | 2507.0 |
| MAPRE1 | 2575.0 |
| CDC45 | 2747.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| ALMS1 | 2804.0 |
| NDC1 | 2860.0 |
| E2F1 | 2922.0 |
| FEN1 | 2933.0 |
| RANBP2 | 3016.0 |
| RAB8A | 3057.0 |
| TUBA3C | 3214.0 |
| SKA1 | 3245.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| NUDC | 3440.0 |
| CENPK | 3476.0 |
| NEK9 | 3481.0 |
| CENPL | 3515.0 |
| TUBB6 | 3539.0 |
| CEP57 | 3574.0 |
| PLK4 | 3579.0 |
| CDC26 | 3611.0 |
| TUBB4A | 3612.0 |
| FBXL18 | 3661.0 |
| PPP1R12B | 3710.0 |
| H3C2 | 3915.0 |
| MCM5 | 3943.0 |
| NUP153 | 4025.0 |
| PRKAR2B | 4071.0 |
| NUP54 | 4170.0 |
| POLA2 | 4192.0 |
| FBXO5 | 4212.0 |
| CCND2 | 4231.0 |
| PPP2R5B | 4232.0 |
| AAAS | 4254.0 |
| CCNE2 | 4280.0 |
| CCND1 | 4294.0 |
| RFC2 | 4313.0 |
| CCND3 | 4317.0 |
| H3-3A | 4335.0 |
| CCNA2 | 4366.0 |
| RBBP4 | 4375.0 |
| PMF1 | 4398.0 |
| CUL1 | 4399.0 |
| HSP90AA1 | 4414.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| RPA3 | 4481.0 |
| PKMYT1 | 4486.0 |
| HAUS2 | 4581.0 |
| CDK4 | 4604.0 |
| RAB1A | 4669.0 |
| MCM2 | 4670.0 |
| AKT1 | 4674.0 |
| CDCA5 | 4721.0 |
| SKP2 | 4760.0 |
| HAUS4 | 4825.0 |
| AURKB | 4877.0 |
| PSMB4 | 4971.0 |
| SPC24 | 5022.0 |
| NEK6 | 5041.0 |
| H4C3 | 5053.0 |
| LMNA | 5119.0 |
| ESCO1 | 5153.0 |
| CDK2 | 5165.0 |
| PSMF1 | 5221.0 |
| KMT5A | 5304.0 |
| PSMD7 | 5305.0 |
| HAUS1 | 5311.0 |
| NUP58 | 5365.0 |
| TAOK1 | 5424.0 |
| UBE2S | 5479.0 |
| SEH1L | 5647.0 |
| RPS27 | 5679.0 |
| PSMB2 | 5803.0 |
| TUBG1 | 5806.0 |
| CEP135 | 5819.0 |
| FBXW11 | 5855.0 |
| PSMB7 | 5858.0 |
| H3C3 | 5902.0 |
| H3C1 | 6001.0 |
| POLD4 | 6046.0 |
| NDC80 | 6086.0 |
| PRKACA | 6168.0 |
| MASTL | 6217.0 |
| TUBB3 | 6221.0 |
| DCTN2 | 6256.0 |
| HAUS8 | 6365.0 |
| ARPP19 | 6373.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| KNL1 | 6545.0 |
| SRC | 6605.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| MZT2B | 6651.0 |
| UBC | 6700.0 |
| E2F4 | 6720.0 |
| PPP2R5D | 6733.0 |
| DYNC1LI1 | 6830.0 |
| H2AC4 | 6905.0 |
| CENPU | 6916.0 |
| PSMA6 | 6984.0 |
| UBE2I | 7189.0 |
| CDC20 | 7234.0 |
| CHMP6 | 7265.0 |
| H2BC21 | 7408.0 |
| NUP155 | 7411.0 |
| CCNE1 | 7482.0 |
| CDKN2B | 7557.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| BUB3 | 7623.0 |
| H2BC12 | 7676.0 |
| PSMB3 | 8017.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| LYN | 8377.0 |
| POLE4 | 8577.0 |
| TK1 | 8605.0 |
| SET | 8685.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| H2AZ1 | 8917.0 |
| LIG1 | 8960.0 |
| KIF23 | 8961.0 |
| H2AC14 | 9376.0 |
| CDKN2D | 9489.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| NINL | 9656.0 |
| PSME1 | 9765.0 |
| H4C12 | 10027.0 |
| ANAPC1 | 10085.0 |
| H2BC14 | 10168.0 |
| RBX1 | 10301.0 |
| PTK6 | 10895.0 |
| TUBB8 | 11325.0 |
REACTOME_M_PHASE
| 1096 | |
|---|---|
| set | REACTOME_M_PHASE |
| setSize | 398 |
| pANOVA | 6e-09 |
| s.dist | -0.17 |
| p.adjustANOVA | 1.64e-06 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| CC2D1B | -9830.0 |
| CHMP2B | -9643.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| GOLGA2 | -9392.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
| POM121C | -9098.0 |
| TUBB4B | -9023.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| LEMD2 | -8856.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| CC2D1B | -9830.0 |
| CHMP2B | -9643.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| INCENP | -9447.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| GOLGA2 | -9392.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| CHMP4A | -9177.0 |
| TUBGCP4 | -9141.0 |
| POM121C | -9098.0 |
| TUBB4B | -9023.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| LEMD2 | -8856.0 |
| VPS4A | -8736.0 |
| RB1 | -8714.0 |
| RAB2A | -8702.0 |
| TUBA1C | -8675.0 |
| ANAPC5 | -8661.0 |
| CENPH | -8616.0 |
| H4C13 | -8603.0 |
| PSMB11 | -8512.0 |
| TUBG2 | -8420.0 |
| NCAPD2 | -8303.0 |
| TUBA3E | -8293.0 |
| POM121 | -8267.0 |
| CEP192 | -8256.0 |
| MZT2A | -8243.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| NDEL1 | -8074.0 |
| MZT1 | -8047.0 |
| PSMC1 | -7848.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| CHMP4C | -7757.0 |
| MAU2 | -7729.0 |
| CEP164 | -7722.0 |
| BLZF1 | -7718.0 |
| CENPO | -7707.0 |
| H2AX | -7648.0 |
| CKAP5 | -7526.0 |
| GORASP2 | -7497.0 |
| PPP2R2D | -7485.0 |
| DYNLL2 | -7477.0 |
| ZWINT | -7442.0 |
| H3C6 | -7372.0 |
| PSMD13 | -7362.0 |
| KIF2C | -7337.0 |
| GORASP1 | -7335.0 |
| NUP214 | -7186.0 |
| PTTG1 | -7163.0 |
| CHMP4B | -7159.0 |
| NCAPH2 | -7155.0 |
| SPAST | -7098.0 |
| ODF2 | -7061.0 |
| NCAPG2 | -7020.0 |
| CCNB2 | -6945.0 |
| NUMA1 | -6884.0 |
| CENPC | -6867.0 |
| NUP88 | -6865.0 |
| ANKLE2 | -6706.0 |
| NCAPD3 | -6668.0 |
| PLK1 | -6633.0 |
| PPP1CC | -6627.0 |
| TUBA4A | -6626.0 |
| PSMD3 | -6608.0 |
| SMC2 | -6571.0 |
| DCTN3 | -6556.0 |
| NUP42 | -6551.0 |
| H2BC10 | -6510.0 |
| PCM1 | -6483.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| CEP152 | -6444.0 |
| PSMD4 | -6409.0 |
| CEP131 | -6383.0 |
| PSMB5 | -6339.0 |
| TUBB2B | -6314.0 |
| CEP72 | -6174.0 |
| CENPF | -6110.0 |
| CSNK2B | -6080.0 |
| ZW10 | -6072.0 |
| MAD2L1 | -6059.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| HAUS5 | -6025.0 |
| TUBB2A | -5979.0 |
| ESPL1 | -5959.0 |
| NUP210 | -5812.0 |
| TUBGCP5 | -5800.0 |
| ANAPC7 | -5789.0 |
| H2AC6 | -5775.0 |
| CLIP1 | -5755.0 |
| H2BC15 | -5694.0 |
| TUBGCP6 | -5669.0 |
| LMNB1 | -5639.0 |
| H3C11 | -5538.0 |
| TPR | -5490.0 |
| SIRT2 | -5451.0 |
| H3-4 | -5447.0 |
| CLASP1 | -5346.0 |
| H2BC6 | -5295.0 |
| PSMC3 | -5262.0 |
| CNEP1R1 | -5168.0 |
| PPP2R5E | -5142.0 |
| DYNC1I2 | -5131.0 |
| CHMP2A | -5098.0 |
| CEP63 | -5092.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| PSME4 | -5053.0 |
| TUBAL3 | -5043.0 |
| TUBA4B | -5020.0 |
| CEP43 | -4973.0 |
| PRKCB | -4898.0 |
| PSMA5 | -4888.0 |
| CHMP3 | -4842.0 |
| CDC23 | -4806.0 |
| CDC27 | -4761.0 |
| SDCCAG8 | -4735.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| KIF2A | -4638.0 |
| TUBA1B | -4624.0 |
| PCNT | -4617.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| H4C6 | -4534.0 |
| CEP250 | -4503.0 |
| NUP85 | -4358.0 |
| UBE2D1 | -4355.0 |
| XPO1 | -4345.0 |
| CLASP2 | -4343.0 |
| NUP98 | -4330.0 |
| PPP2R2A | -4274.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| H2BC17 | -4192.0 |
| CEP41 | -4178.0 |
| UBE2E1 | -4108.0 |
| USO1 | -4080.0 |
| TUBA8 | -4032.0 |
| PSMD1 | -3979.0 |
| WAPL | -3947.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| H4C4 | -3867.0 |
| CENPA | -3845.0 |
| H2AJ | -3814.0 |
| CNTRL | -3781.0 |
| CEP76 | -3720.0 |
| KNTC1 | -3683.0 |
| ANAPC2 | -3617.0 |
| H2BC26 | -3582.0 |
| NDE1 | -3562.0 |
| DYNLL1 | -3550.0 |
| NUF2 | -3541.0 |
| NIPBL | -3507.0 |
| NUP133 | -3446.0 |
| SPDL1 | -3370.0 |
| MAD1L1 | -3364.0 |
| AKAP9 | -3238.0 |
| ANAPC15 | -3203.0 |
| PSMC4 | -3089.0 |
| RAD21 | -3080.0 |
| ZWILCH | -3078.0 |
| LPIN1 | -2997.0 |
| RCC2 | -2861.0 |
| NUP188 | -2837.0 |
| PSMB1 | -2799.0 |
| ITGB3BP | -2777.0 |
| CENPQ | -2767.0 |
| CEP70 | -2717.0 |
| B9D2 | -2628.0 |
| LEMD3 | -2627.0 |
| RANGAP1 | -2606.0 |
| NUP205 | -2593.0 |
| PAFAH1B1 | -2571.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| MCPH1 | -2431.0 |
| BIRC5 | -2354.0 |
| CDK1 | -2219.0 |
| LPIN3 | -2143.0 |
| PSMC6 | -2126.0 |
| DYNC1I1 | -2088.0 |
| CENPT | -2076.0 |
| PDS5B | -2067.0 |
| LPIN2 | -2033.0 |
| RAN | -2031.0 |
| HAUS6 | -2029.0 |
| CSNK2A2 | -2019.0 |
| CEP290 | -2002.0 |
| TUBGCP3 | -1900.0 |
| TUBA1A | -1819.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| TMPO | -1743.0 |
| PSMB9 | -1684.0 |
| CHMP7 | -1636.0 |
| LBR | -1592.0 |
| H2AC8 | -1573.0 |
| CDK5RAP2 | -1570.0 |
| KPNB1 | -1539.0 |
| CCP110 | -1489.0 |
| PSMA3 | -1391.0 |
| PSME3 | -1153.0 |
| SGO1 | -1080.0 |
| PRKCA | -1066.0 |
| PDS5A | -1046.0 |
| H2BC8 | -1029.0 |
| ANAPC11 | -1014.0 |
| CDCA8 | -916.0 |
| NCAPG | -857.0 |
| TNPO1 | -607.0 |
| NEK7 | -599.0 |
| NCAPH | -562.0 |
| CENPP | -551.0 |
| YWHAE | -521.0 |
| NUP160 | -518.0 |
| PSMA1 | -477.0 |
| H2AZ2 | -340.0 |
| DCTN1 | -338.0 |
| DSN1 | -331.0 |
| TUBGCP2 | -268.0 |
| PSMB8 | -260.0 |
| NEK2 | -182.0 |
| UBA52 | -167.0 |
| STAG1 | -147.0 |
| H3-3B | -135.0 |
| AHCTF1 | -75.0 |
| KIF2B | -57.0 |
| CEP78 | 13.0 |
| MAPK1 | 78.0 |
| YWHAG | 115.0 |
| IST1 | 123.0 |
| TUBB | 261.0 |
| SKA2 | 265.0 |
| NUP37 | 339.0 |
| BUB1B | 349.0 |
| PSMB10 | 447.0 |
| VRK2 | 465.0 |
| EML4 | 552.0 |
| BUB1 | 660.0 |
| RAB1B | 777.0 |
| NEDD1 | 779.0 |
| SMC4 | 787.0 |
| NSL1 | 804.0 |
| BANF1 | 835.0 |
| CENPS | 874.0 |
| H4C5 | 878.0 |
| ENSA | 893.0 |
| PSMD12 | 901.0 |
| SEC13 | 959.0 |
| KIF18A | 960.0 |
| HAUS3 | 961.0 |
| NME7 | 1011.0 |
| CENPJ | 1016.0 |
| CDC16 | 1047.0 |
| TUBB1 | 1069.0 |
| KIF20A | 1088.0 |
| SMC3 | 1172.0 |
| PSMD14 | 1213.0 |
| CSNK1E | 1281.0 |
| CENPM | 1294.0 |
| SPC25 | 1348.0 |
| PPP2R5A | 1480.0 |
| RCC1 | 1490.0 |
| CSNK1D | 1496.0 |
| NUP62 | 1710.0 |
| SEM1 | 1794.0 |
| RPS27A | 1846.0 |
| CENPN | 1892.0 |
| MIS12 | 1902.0 |
| CTDNEP1 | 1909.0 |
| H2BC3 | 1920.0 |
| CSNK2A1 | 2040.0 |
| SUMO1 | 2052.0 |
| SSNA1 | 2103.0 |
| PSMC5 | 2183.0 |
| RAE1 | 2192.0 |
| ACTR1A | 2220.0 |
| PSMD8 | 2235.0 |
| CENPE | 2236.0 |
| SFI1 | 2352.0 |
| PPP2R5C | 2434.0 |
| MAPK3 | 2444.0 |
| MAPRE1 | 2575.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| ALMS1 | 2804.0 |
| NDC1 | 2860.0 |
| RANBP2 | 3016.0 |
| TUBA3C | 3214.0 |
| SKA1 | 3245.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| NUDC | 3440.0 |
| CENPK | 3476.0 |
| NEK9 | 3481.0 |
| CENPL | 3515.0 |
| TUBB6 | 3539.0 |
| CEP57 | 3574.0 |
| PLK4 | 3579.0 |
| CDC26 | 3611.0 |
| TUBB4A | 3612.0 |
| H3C2 | 3915.0 |
| NUP153 | 4025.0 |
| PRKAR2B | 4071.0 |
| NUP54 | 4170.0 |
| FBXO5 | 4212.0 |
| PPP2R5B | 4232.0 |
| AAAS | 4254.0 |
| H3-3A | 4335.0 |
| PMF1 | 4398.0 |
| HSP90AA1 | 4414.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| HAUS2 | 4581.0 |
| RAB1A | 4669.0 |
| CDCA5 | 4721.0 |
| HAUS4 | 4825.0 |
| AURKB | 4877.0 |
| PSMB4 | 4971.0 |
| SPC24 | 5022.0 |
| NEK6 | 5041.0 |
| H4C3 | 5053.0 |
| LMNA | 5119.0 |
| PSMF1 | 5221.0 |
| KMT5A | 5304.0 |
| PSMD7 | 5305.0 |
| HAUS1 | 5311.0 |
| NUP58 | 5365.0 |
| TAOK1 | 5424.0 |
| UBE2S | 5479.0 |
| SEH1L | 5647.0 |
| RPS27 | 5679.0 |
| PSMB2 | 5803.0 |
| TUBG1 | 5806.0 |
| CEP135 | 5819.0 |
| PSMB7 | 5858.0 |
| H3C3 | 5902.0 |
| H3C1 | 6001.0 |
| NDC80 | 6086.0 |
| PRKACA | 6168.0 |
| MASTL | 6217.0 |
| TUBB3 | 6221.0 |
| DCTN2 | 6256.0 |
| HAUS8 | 6365.0 |
| ARPP19 | 6373.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| KNL1 | 6545.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| MZT2B | 6651.0 |
| UBC | 6700.0 |
| PPP2R5D | 6733.0 |
| DYNC1LI1 | 6830.0 |
| H2AC4 | 6905.0 |
| CENPU | 6916.0 |
| PSMA6 | 6984.0 |
| UBE2I | 7189.0 |
| CDC20 | 7234.0 |
| CHMP6 | 7265.0 |
| H2BC21 | 7408.0 |
| NUP155 | 7411.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| BUB3 | 7623.0 |
| H2BC12 | 7676.0 |
| PSMB3 | 8017.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| SET | 8685.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| H2AZ1 | 8917.0 |
| KIF23 | 8961.0 |
| H2AC14 | 9376.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| NINL | 9656.0 |
| PSME1 | 9765.0 |
| H4C12 | 10027.0 |
| ANAPC1 | 10085.0 |
| H2BC14 | 10168.0 |
| TUBB8 | 11325.0 |
REACTOME_KERATINIZATION
| 1073 | |
|---|---|
| set | REACTOME_KERATINIZATION |
| setSize | 210 |
| pANOVA | 1.21e-06 |
| s.dist | 0.194 |
| p.adjustANOVA | 0.000284 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRTAP19-1 | 11464 |
| KRT16 | 11459 |
| SPRR2E | 11441 |
| KRTAP1-3 | 11412 |
| LCE4A | 11411 |
| KRTAP4-7 | 11306 |
| KRTAP10-2 | 11229 |
| LCE3D | 11143 |
| KRTAP5-3 | 11063 |
| LIPN | 11061 |
| KRTAP10-1 | 11031 |
| KRTAP3-3 | 10991 |
| KRTAP24-1 | 10984 |
| KRT80 | 10981 |
| KRTAP9-1 | 10946 |
| KRT14 | 10942 |
| KRT31 | 10784 |
| DSG4 | 10774 |
| KRT13 | 10770 |
| KRTAP2-4 | 10765 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRTAP19-1 | 11464 |
| KRT16 | 11459 |
| SPRR2E | 11441 |
| KRTAP1-3 | 11412 |
| LCE4A | 11411 |
| KRTAP4-7 | 11306 |
| KRTAP10-2 | 11229 |
| LCE3D | 11143 |
| KRTAP5-3 | 11063 |
| LIPN | 11061 |
| KRTAP10-1 | 11031 |
| KRTAP3-3 | 10991 |
| KRTAP24-1 | 10984 |
| KRT80 | 10981 |
| KRTAP9-1 | 10946 |
| KRT14 | 10942 |
| KRT31 | 10784 |
| DSG4 | 10774 |
| KRT13 | 10770 |
| KRTAP2-4 | 10765 |
| KRT32 | 10757 |
| KRT2 | 10708 |
| KRTAP10-10 | 10698 |
| KRTAP4-8 | 10692 |
| KRTAP13-3 | 10603 |
| KRT20 | 10595 |
| CDSN | 10570 |
| KRTAP4-5 | 10503 |
| KRT8 | 10480 |
| SPRR1B | 10465 |
| KRT23 | 10425 |
| PI3 | 10310 |
| LCE1C | 10305 |
| KRTAP1-4 | 10252 |
| KRTAP19-4 | 10235 |
| KRT24 | 10051 |
| KRTAP3-1 | 10031 |
| KRT3 | 9980 |
| LCE3A | 9928 |
| KRTAP26-1 | 9913 |
| KRT78 | 9667 |
| KRT18 | 9618 |
| KRTAP4-4 | 9578 |
| LCE2A | 9513 |
| KRTAP21-1 | 9507 |
| IVL | 9424 |
| KRTAP1-5 | 9405 |
| KRT76 | 9394 |
| KRT6A | 9356 |
| KRTAP4-3 | 9330 |
| KRT83 | 9327 |
| KRTAP10-4 | 9320 |
| KRT5 | 9228 |
| KRT74 | 9190 |
| KRTAP10-7 | 9117 |
| KRTAP19-3 | 8924 |
| RPTN | 8839 |
| SPINK5 | 8763 |
| PRSS8 | 8717 |
| SPRR3 | 8681 |
| KRTAP19-8 | 8553 |
| KAZN | 8550 |
| KRTAP9-3 | 8546 |
| KRTAP17-1 | 8499 |
| TGM5 | 8471 |
| SPINK9 | 8439 |
| KRTAP20-2 | 8434 |
| KRTAP5-2 | 8326 |
| KRTAP6-2 | 8222 |
| ST14 | 7991 |
| KRTAP9-4 | 7989 |
| KRTAP4-6 | 7939 |
| KRT17 | 7897 |
| KRTAP4-1 | 7872 |
| EVPL | 7863 |
| DSG1 | 7819 |
| KRT9 | 7746 |
| PCSK6 | 7678 |
| KRT34 | 7585 |
| KRT79 | 7575 |
| KRTAP5-9 | 7486 |
| LELP1 | 7416 |
| KRTAP29-1 | 7306 |
| FURIN | 7240 |
| KRT25 | 7197 |
| KRT7 | 7162 |
| KRT1 | 7101 |
| KLK12 | 7087 |
| KRT38 | 7043 |
| KRT40 | 6970 |
| LCE6A | 6693 |
| KRTAP19-2 | 6668 |
| KRTAP12-1 | 6633 |
| KRTAP22-1 | 6632 |
| KRTAP2-3 | 6549 |
| KRTAP10-3 | 6374 |
| KRT82 | 6361 |
| PKP3 | 6320 |
| KRTAP23-1 | 6193 |
| KRT28 | 5810 |
| PERP | 5738 |
| KRT37 | 5578 |
| SPRR1A | 5570 |
| DSG3 | 5522 |
| LCE3E | 5472 |
| KRTAP9-9 | 5079 |
| KRTAP19-5 | 5051 |
| JUP | 5024 |
| KRT71 | 5013 |
| SPRR2G | 5000 |
| KRT72 | 4813 |
| KRTAP25-1 | 4502 |
| KRTAP13-1 | 4342 |
| KRT4 | 4263 |
| KRT15 | 4262 |
| LCE3B | 4204 |
| KRT73 | 4201 |
| KRT35 | 3684 |
| KRTAP6-1 | 3475 |
| KRTAP19-6 | 3382 |
| KRTAP1-1 | 3304 |
| KRT19 | 3180 |
| LCE2D | 3089 |
| LIPJ | 2824 |
| KRTAP10-12 | 2473 |
| SPRR2F | 2394 |
| KRT81 | 1658 |
| LCE1A | 1598 |
| KLK8 | 1177 |
| KRTAP5-6 | 1163 |
| KRTAP12-4 | 1096 |
| KRT33B | 977 |
| KRT12 | 469 |
| DSG2 | 220 |
| KLK13 | 69 |
| KRTAP12-3 | -404 |
| KRTAP10-6 | -672 |
| KRT10 | -795 |
| KRTAP5-5 | -843 |
| KLK5 | -868 |
| KRT77 | -898 |
| LCE1B | -1088 |
| KRT75 | -1360 |
| KRT26 | -1487 |
| SPRR2A | -2009 |
| KRTAP9-6 | -2095 |
| KRTAP5-7 | -2254 |
| TGM1 | -2458 |
| CASP14 | -2646 |
| KRT85 | -2758 |
| CAPN1 | -2768 |
| KRTAP20-1 | -2867 |
| PPL | -3126 |
| DSP | -3279 |
| KRTAP19-7 | -3351 |
| PKP4 | -3389 |
| KLK14 | -3497 |
| KRTAP21-2 | -4048 |
| KRTAP2-1 | -4285 |
| KRTAP10-11 | -4783 |
| KRT86 | -5820 |
| CELA2A | -6063 |
| KRTAP16-1 | -6114 |
| KRTAP21-3 | -6370 |
| FLG | -6381 |
| SPINK6 | -6455 |
| KRTAP3-2 | -6520 |
| PKP2 | -6745 |
| LIPK | -6846 |
| LCE1F | -6991 |
| KRTAP10-5 | -7071 |
| LCE1E | -7262 |
| SPRR2D | -7277 |
| TCHH | -7381 |
| PKP1 | -7582 |
| KRT36 | -7603 |
| CSTA | -7732 |
| KRTAP8-1 | -7832 |
| KRTAP5-4 | -7969 |
| KRT84 | -8057 |
| LCE5A | -8252 |
| KRT27 | -8333 |
| KRTAP12-2 | -8363 |
| DSC2 | -8380 |
| KRTAP11-1 | -8418 |
| KRTAP15-1 | -8430 |
| LCE2B | -8454 |
| KRTAP10-8 | -8600 |
| DSC1 | -8825 |
| LIPM | -8866 |
| KRT33A | -8895 |
| CAPNS1 | -8896 |
| KRTAP5-11 | -8954 |
| LCE2C | -8992 |
| KRT6C | -9007 |
| KRT39 | -9087 |
| KRTAP6-3 | -9133 |
| KRT6B | -9247 |
| KRTAP10-9 | -9262 |
| KRTAP2-2 | -9603 |
| KRTAP27-1 | -9607 |
| KRTAP13-2 | -9644 |
| KRTAP4-2 | -9798 |
| KRTAP13-4 | -9836 |
| KRTAP5-1 | -9877 |
| KRTAP9-2 | -9975 |
| DSC3 | -10016 |
| KRTAP4-11 | -10046 |
| KRTAP5-10 | -10278 |
| KRTAP5-8 | -10412 |
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE
| 500 | |
|---|---|
| set | REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE |
| setSize | 228 |
| pANOVA | 5.41e-06 |
| s.dist | -0.175 |
| p.adjustANOVA | 0.00111 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| UBE2C | -9474 |
| INCENP | -9447 |
| VRK1 | -9290 |
| PPP2R1B | -9252 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| PSMD2 | -8887 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| ANAPC5 | -8661 |
| CENPH | -8616 |
| PSMB11 | -8512 |
| TUBA3E | -8293 |
| POM121 | -8267 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| UBE2C | -9474 |
| INCENP | -9447 |
| VRK1 | -9290 |
| PPP2R1B | -9252 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| PSMD2 | -8887 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| ANAPC5 | -8661 |
| CENPH | -8616 |
| PSMB11 | -8512 |
| TUBA3E | -8293 |
| POM121 | -8267 |
| NDEL1 | -8074 |
| PSMC1 | -7848 |
| ANAPC4 | -7831 |
| CHMP4C | -7757 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| PSMD13 | -7362 |
| KIF2C | -7337 |
| PTTG1 | -7163 |
| CHMP4B | -7159 |
| SPAST | -7098 |
| CCNB2 | -6945 |
| CENPC | -6867 |
| ANKLE2 | -6706 |
| PLK1 | -6633 |
| PPP1CC | -6627 |
| TUBA4A | -6626 |
| PSMD3 | -6608 |
| DYNC1H1 | -6464 |
| PSMD9 | -6463 |
| PSMD4 | -6409 |
| PSMB5 | -6339 |
| TUBB2B | -6314 |
| CENPF | -6110 |
| ZW10 | -6072 |
| MAD2L1 | -6059 |
| PSMD11 | -6044 |
| PSMC2 | -6032 |
| TUBB2A | -5979 |
| ESPL1 | -5959 |
| ANAPC7 | -5789 |
| CLIP1 | -5755 |
| LMNB1 | -5639 |
| SIRT2 | -5451 |
| CLASP1 | -5346 |
| PSMC3 | -5262 |
| PPP2R5E | -5142 |
| DYNC1I2 | -5131 |
| CHMP2A | -5098 |
| PSME4 | -5053 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| PSMA5 | -4888 |
| CHMP3 | -4842 |
| CDC23 | -4806 |
| CDC27 | -4761 |
| DYNC1LI2 | -4730 |
| PSMD5 | -4711 |
| KIF2A | -4638 |
| TUBA1B | -4624 |
| NUP107 | -4561 |
| NUP85 | -4358 |
| UBE2D1 | -4355 |
| XPO1 | -4345 |
| CLASP2 | -4343 |
| NUP98 | -4330 |
| PPP2R2A | -4274 |
| PSMB6 | -4271 |
| UBE2E1 | -4108 |
| TUBA8 | -4032 |
| PSMD1 | -3979 |
| WAPL | -3947 |
| NUP43 | -3906 |
| NUP35 | -3876 |
| CENPA | -3845 |
| KNTC1 | -3683 |
| ANAPC2 | -3617 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| NUF2 | -3541 |
| NUP133 | -3446 |
| SPDL1 | -3370 |
| MAD1L1 | -3364 |
| ANAPC15 | -3203 |
| PSMC4 | -3089 |
| RAD21 | -3080 |
| ZWILCH | -3078 |
| RCC2 | -2861 |
| NUP188 | -2837 |
| PSMB1 | -2799 |
| ITGB3BP | -2777 |
| CENPQ | -2767 |
| B9D2 | -2628 |
| LEMD3 | -2627 |
| RANGAP1 | -2606 |
| NUP205 | -2593 |
| PAFAH1B1 | -2571 |
| PSMA2 | -2485 |
| BIRC5 | -2354 |
| CDK1 | -2219 |
| PSMC6 | -2126 |
| DYNC1I1 | -2088 |
| CENPT | -2076 |
| PDS5B | -2067 |
| RAN | -2031 |
| TUBA1A | -1819 |
| ANAPC16 | -1795 |
| TMPO | -1743 |
| PSMB9 | -1684 |
| CHMP7 | -1636 |
| LBR | -1592 |
| KPNB1 | -1539 |
| PSMA3 | -1391 |
| PSME3 | -1153 |
| SGO1 | -1080 |
| PDS5A | -1046 |
| ANAPC11 | -1014 |
| CDCA8 | -916 |
| TNPO1 | -607 |
| CENPP | -551 |
| NUP160 | -518 |
| PSMA1 | -477 |
| DSN1 | -331 |
| PSMB8 | -260 |
| UBA52 | -167 |
| STAG1 | -147 |
| AHCTF1 | -75 |
| KIF2B | -57 |
| IST1 | 123 |
| SKA2 | 265 |
| NUP37 | 339 |
| BUB1B | 349 |
| PSMB10 | 447 |
| VRK2 | 465 |
| BUB1 | 660 |
| NSL1 | 804 |
| BANF1 | 835 |
| CENPS | 874 |
| PSMD12 | 901 |
| SEC13 | 959 |
| KIF18A | 960 |
| CDC16 | 1047 |
| TUBB1 | 1069 |
| SMC3 | 1172 |
| PSMD14 | 1213 |
| CENPM | 1294 |
| SPC25 | 1348 |
| PPP2R5A | 1480 |
| RCC1 | 1490 |
| NUP62 | 1710 |
| SEM1 | 1794 |
| RPS27A | 1846 |
| CENPN | 1892 |
| MIS12 | 1902 |
| SUMO1 | 2052 |
| PSMC5 | 2183 |
| PSMD8 | 2235 |
| CENPE | 2236 |
| PPP2R5C | 2434 |
| MAPRE1 | 2575 |
| NUP93 | 2760 |
| NDC1 | 2860 |
| RANBP2 | 3016 |
| TUBA3C | 3214 |
| SKA1 | 3245 |
| PPP2CB | 3417 |
| NUDC | 3440 |
| CENPK | 3476 |
| CENPL | 3515 |
| TUBB6 | 3539 |
| CDC26 | 3611 |
| TUBB4A | 3612 |
| NUP54 | 4170 |
| FBXO5 | 4212 |
| PPP2R5B | 4232 |
| PMF1 | 4398 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| CDCA5 | 4721 |
| AURKB | 4877 |
| PSMB4 | 4971 |
| SPC24 | 5022 |
| LMNA | 5119 |
| PSMF1 | 5221 |
| PSMD7 | 5305 |
| NUP58 | 5365 |
| TAOK1 | 5424 |
| UBE2S | 5479 |
| SEH1L | 5647 |
| RPS27 | 5679 |
| PSMB2 | 5803 |
| PSMB7 | 5858 |
| NDC80 | 6086 |
| TUBB3 | 6221 |
| ANAPC10 | 6467 |
| PSMA8 | 6502 |
| KNL1 | 6545 |
| PSMD6 | 6616 |
| PSME2 | 6638 |
| UBC | 6700 |
| PPP2R5D | 6733 |
| DYNC1LI1 | 6830 |
| CENPU | 6916 |
| PSMA6 | 6984 |
| UBE2I | 7189 |
| CDC20 | 7234 |
| CHMP6 | 7265 |
| NUP155 | 7411 |
| PSMA4 | 7568 |
| UBB | 7594 |
| BUB3 | 7623 |
| PSMB3 | 8017 |
| PSMA7 | 9563 |
| PSME1 | 9765 |
| ANAPC1 | 10085 |
| TUBB8 | 11325 |
REACTOME_METABOLISM_OF_RNA
| 1313 | |
|---|---|
| set | REACTOME_METABOLISM_OF_RNA |
| setSize | 675 |
| pANOVA | 1.76e-05 |
| s.dist | -0.0969 |
| p.adjustANOVA | 0.00299 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| UTP14C | -9847 |
| EIF4A3 | -9788 |
| TRMT44 | -9689 |
| CNOT6 | -9599 |
| DDX39B | -9566 |
| TPRKB | -9490 |
| RPP30 | -9463 |
| PWP2 | -9437 |
| KHSRP | -9345 |
| DHX16 | -9334 |
| SNRNP200 | -9279 |
| TCERG1 | -9231 |
| NOL6 | -9173 |
| GPATCH1 | -9155 |
| AQR | -9124 |
| POM121C | -9098 |
| SMU1 | -9068 |
| RPS23 | -9035 |
| APOBEC3H | -9010 |
| PPIE | -8917 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| UTP14C | -9847.0 |
| EIF4A3 | -9788.0 |
| TRMT44 | -9689.0 |
| CNOT6 | -9599.0 |
| DDX39B | -9566.0 |
| TPRKB | -9490.0 |
| RPP30 | -9463.0 |
| PWP2 | -9437.0 |
| KHSRP | -9345.0 |
| DHX16 | -9334.0 |
| SNRNP200 | -9279.0 |
| TCERG1 | -9231.0 |
| NOL6 | -9173.0 |
| GPATCH1 | -9155.0 |
| AQR | -9124.0 |
| POM121C | -9098.0 |
| SMU1 | -9068.0 |
| RPS23 | -9035.0 |
| APOBEC3H | -9010.0 |
| PPIE | -8917.0 |
| PSMD2 | -8887.0 |
| SNU13 | -8840.0 |
| SMG1 | -8814.0 |
| NSRP1 | -8755.0 |
| TRMT13 | -8738.0 |
| DDX47 | -8733.0 |
| BUD31 | -8705.0 |
| HNRNPH1 | -8685.0 |
| DHX38 | -8620.0 |
| CHERP | -8573.0 |
| YJU2 | -8567.0 |
| BYSL | -8566.0 |
| WDR70 | -8530.0 |
| PSMB11 | -8512.0 |
| CPSF2 | -8474.0 |
| PABPN1 | -8466.0 |
| RPL32 | -8431.0 |
| CWC22 | -8401.0 |
| CNOT6L | -8328.0 |
| GTPBP3 | -8296.0 |
| POM121 | -8267.0 |
| SNRNP70 | -8255.0 |
| RPP38 | -8229.0 |
| SLU7 | -8211.0 |
| SKIC3 | -8205.0 |
| TRMT12 | -8101.0 |
| SNRNP48 | -8100.0 |
| CNOT1 | -8093.0 |
| GEMIN2 | -8034.0 |
| YWHAB | -8002.0 |
| RBM8A | -7974.0 |
| WDR3 | -7962.0 |
| RBM5 | -7948.0 |
| PPP1R8 | -7943.0 |
| SF3B5 | -7928.0 |
| HEATR1 | -7888.0 |
| RCL1 | -7869.0 |
| PSMC1 | -7848.0 |
| UTP20 | -7766.0 |
| RPL34 | -7701.0 |
| CNOT9 | -7665.0 |
| RNPC3 | -7642.0 |
| SRSF9 | -7628.0 |
| SF3A3 | -7579.0 |
| APOBEC4 | -7563.0 |
| POP4 | -7537.0 |
| ELAC2 | -7531.0 |
| POLR2A | -7443.0 |
| GLE1 | -7413.0 |
| PRPF3 | -7409.0 |
| SNIP1 | -7405.0 |
| RPL26 | -7370.0 |
| PSMD13 | -7362.0 |
| CNOT8 | -7355.0 |
| LUC7L3 | -7296.0 |
| APOBEC2 | -7264.0 |
| TRIT1 | -7210.0 |
| NUP214 | -7186.0 |
| CPSF4 | -7145.0 |
| SNRPB | -7144.0 |
| BUD13 | -7079.0 |
| RPPH1 | -7056.0 |
| FBL | -7037.0 |
| ADAT3 | -7004.0 |
| PARN | -6996.0 |
| PPIL3 | -6952.0 |
| U2SURP | -6931.0 |
| CTU1 | -6927.0 |
| NUP88 | -6865.0 |
| CWF19L2 | -6798.0 |
| NCBP1 | -6659.0 |
| SRSF2 | -6648.0 |
| SNRPD2 | -6623.0 |
| PSMD3 | -6608.0 |
| NUP42 | -6551.0 |
| OSGEP | -6526.0 |
| DDX49 | -6519.0 |
| ZMAT5 | -6486.0 |
| EXOSC3 | -6479.0 |
| TFB1M | -6471.0 |
| TEX10 | -6466.0 |
| PSMD9 | -6463.0 |
| SUGP1 | -6448.0 |
| PSMD4 | -6409.0 |
| TFIP11 | -6393.0 |
| POLR2K | -6386.0 |
| C2orf49 | -6371.0 |
| PSMB5 | -6339.0 |
| FAU | -6249.0 |
| EXOSC7 | -6246.0 |
| LSM2 | -6210.0 |
| SRRM1 | -6188.0 |
| SKIC2 | -6117.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| RNPS1 | -5988.0 |
| THOC7 | -5974.0 |
| SNRNP40 | -5897.0 |
| NSUN6 | -5895.0 |
| UTP3 | -5893.0 |
| BCAS2 | -5871.0 |
| MRM2 | -5844.0 |
| RPS20 | -5836.0 |
| PRPF18 | -5822.0 |
| NUP210 | -5812.0 |
| NOP58 | -5810.0 |
| ALYREF | -5793.0 |
| WDR18 | -5783.0 |
| CCAR1 | -5744.0 |
| TSEN54 | -5736.0 |
| NOC4L | -5700.0 |
| TSEN2 | -5621.0 |
| PNN | -5581.0 |
| RBM22 | -5571.0 |
| RPL31 | -5535.0 |
| WDR36 | -5533.0 |
| LCMT2 | -5518.0 |
| EDC4 | -5513.0 |
| NOB1 | -5499.0 |
| TPR | -5490.0 |
| PRCC | -5481.0 |
| XPOT | -5469.0 |
| NIP7 | -5465.0 |
| SF3B4 | -5403.0 |
| CSTF3 | -5380.0 |
| PCF11 | -5372.0 |
| CTNNBL1 | -5340.0 |
| TSEN15 | -5335.0 |
| DCP1A | -5333.0 |
| CHTOP | -5318.0 |
| RPS16 | -5300.0 |
| PSMC3 | -5262.0 |
| RPL10A | -5247.0 |
| PUS7 | -5233.0 |
| UTP11 | -5213.0 |
| RPS6 | -5123.0 |
| RPL36AL | -5105.5 |
| PSME4 | -5053.0 |
| PRPF38A | -5034.0 |
| RPL24 | -5029.0 |
| RPS7 | -5010.0 |
| LSM3 | -4982.0 |
| TRDMT1 | -4978.0 |
| LSM8 | -4946.0 |
| XRN1 | -4944.0 |
| TRMT9B | -4920.0 |
| TRNT1 | -4917.0 |
| RPS13 | -4901.0 |
| PSMA5 | -4888.0 |
| RBM17 | -4872.0 |
| METTL3 | -4781.0 |
| ERCC3 | -4773.0 |
| CNOT4 | -4772.0 |
| CRNKL1 | -4726.0 |
| PSMD5 | -4711.0 |
| PRMT5 | -4702.0 |
| SF3A2 | -4651.0 |
| RPL9 | -4637.0 |
| DDX1 | -4615.0 |
| WDR4 | -4599.0 |
| TYW3 | -4587.0 |
| DDX6 | -4579.0 |
| POLR2J | -4576.0 |
| PPIL1 | -4564.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| RPL22 | -4542.0 |
| RPL29 | -4535.0 |
| NSUN2 | -4509.0 |
| PES1 | -4478.0 |
| CDK7 | -4467.0 |
| ACIN1 | -4440.0 |
| MTO1 | -4411.0 |
| NUP85 | -4358.0 |
| THOC1 | -4354.0 |
| PRPF19 | -4349.0 |
| XPO1 | -4345.0 |
| NUP98 | -4330.0 |
| MPHOSPH10 | -4310.0 |
| PPP2R2A | -4274.0 |
| PSMB6 | -4271.0 |
| RPS12 | -4260.0 |
| CLNS1A | -4224.0 |
| DNAJC8 | -4175.0 |
| FUS | -4173.0 |
| RRP7A | -4171.0 |
| ISY1 | -4170.0 |
| THG1L | -4151.0 |
| POLR2B | -4142.0 |
| EXOSC10 | -4133.0 |
| RNGTT | -3990.0 |
| PSMD1 | -3979.0 |
| LSM4 | -3953.0 |
| MPHOSPH6 | -3949.0 |
| CNOT3 | -3917.0 |
| NUP43 | -3906.0 |
| RPS26 | -3889.0 |
| METTL1 | -3879.0 |
| NUP35 | -3876.0 |
| SRSF12 | -3860.0 |
| GEMIN5 | -3856.0 |
| WDR33 | -3854.0 |
| SRRM2 | -3777.0 |
| SRSF5 | -3776.0 |
| RPP40 | -3737.0 |
| PUF60 | -3724.0 |
| DHX9 | -3722.0 |
| LSM5 | -3706.0 |
| DDX23 | -3700.0 |
| NOL11 | -3657.0 |
| TSR1 | -3637.0 |
| TUT4 | -3543.0 |
| UTP4 | -3494.0 |
| SRSF6 | -3471.0 |
| NUP133 | -3446.0 |
| GTF2F1 | -3422.0 |
| CNOT7 | -3417.0 |
| DDX52 | -3397.0 |
| RBM42 | -3380.0 |
| PHAX | -3324.0 |
| PAN3 | -3309.0 |
| UBL5 | -3297.0 |
| SRSF8 | -3290.0 |
| RPS3A | -3283.0 |
| MRM3 | -3234.0 |
| YBX1 | -3218.0 |
| CNOT2 | -3204.0 |
| TYW5 | -3171.0 |
| RRP36 | -3168.0 |
| POP1 | -3155.0 |
| PSMC4 | -3089.0 |
| LSM11 | -3033.0 |
| SNRPN | -3030.0 |
| BMS1 | -3017.0 |
| DDX46 | -2992.0 |
| SKIC8 | -2957.0 |
| MAPK14 | -2900.0 |
| RPL8 | -2868.0 |
| HNRNPR | -2852.0 |
| NUP188 | -2837.0 |
| XRN2 | -2801.0 |
| PSMB1 | -2799.0 |
| SMG5 | -2780.0 |
| HNRNPA1 | -2749.0 |
| ZC3H11A | -2721.0 |
| WDR43 | -2708.0 |
| ISG20L2 | -2705.0 |
| MAPKAPK2 | -2687.0 |
| EXOSC4 | -2680.0 |
| URM1 | -2639.0 |
| TGS1 | -2634.0 |
| NUP205 | -2593.0 |
| ELAVL1 | -2592.0 |
| IMP4 | -2529.0 |
| PSMA2 | -2485.0 |
| RBM25 | -2456.0 |
| RPL14 | -2453.0 |
| C1D | -2417.0 |
| NOP10 | -2370.0 |
| NT5C3B | -2338.0 |
| CSTF2T | -2324.0 |
| SYMPK | -2309.0 |
| CCNH | -2298.0 |
| RTRAF | -2291.0 |
| UTP6 | -2272.0 |
| SNRNP27 | -2216.0 |
| SART1 | -2165.0 |
| THADA | -2156.0 |
| PSMC6 | -2126.0 |
| PABPC1 | -2051.0 |
| EXOSC2 | -2039.0 |
| RAN | -2031.0 |
| RPL38 | -2006.0 |
| MNAT1 | -1983.0 |
| NAT10 | -1864.0 |
| PNO1 | -1831.0 |
| GTF2H1 | -1823.0 |
| DHX8 | -1818.0 |
| QTRT2 | -1806.0 |
| TUT7 | -1797.0 |
| PPIL2 | -1788.0 |
| SNRPD1 | -1764.0 |
| HNRNPM | -1739.0 |
| PHF5A | -1705.0 |
| FCF1 | -1697.0 |
| PSMB9 | -1684.0 |
| RBM28 | -1683.0 |
| HNRNPA2B1 | -1681.0 |
| CDKAL1 | -1675.0 |
| EMG1 | -1663.0 |
| ALKBH8 | -1662.0 |
| SNW1 | -1658.0 |
| RPS21 | -1653.0 |
| RPP14 | -1649.0 |
| GTF2F2 | -1647.0 |
| EFTUD2 | -1614.0 |
| DHX37 | -1611.0 |
| PUS1 | -1588.0 |
| WDR12 | -1563.0 |
| LTV1 | -1535.0 |
| UTP18 | -1517.0 |
| POLR2H | -1463.0 |
| TXNL4A | -1415.0 |
| PSMA3 | -1391.0 |
| PAPOLA | -1301.0 |
| HBS1L | -1247.0 |
| WTAP | -1237.0 |
| NOP56 | -1229.0 |
| LSM1 | -1180.0 |
| PSME3 | -1153.0 |
| PDCD7 | -1150.0 |
| HNRNPA3 | -1141.0 |
| PLRG1 | -1130.0 |
| PRKCA | -1066.0 |
| DCP1B | -1062.0 |
| SMG8 | -1054.0 |
| SENP3 | -1042.0 |
| SF3A1 | -1025.0 |
| SMG6 | -1008.0 |
| TRMT10C | -943.0 |
| NOP2 | -936.0 |
| DHX15 | -922.0 |
| NOP14 | -890.0 |
| PUS3 | -887.0 |
| PELP1 | -884.0 |
| NOL12 | -873.0 |
| BOP1 | -852.0 |
| CWC27 | -851.0 |
| IGF2BP3 | -849.0 |
| HNRNPD | -848.0 |
| HNRNPL | -818.0 |
| RPL21 | -801.0 |
| DCP2 | -774.0 |
| RPP25 | -756.0 |
| HSPB1 | -744.0 |
| TRMT6 | -725.0 |
| APOBEC3C | -635.0 |
| TNPO1 | -607.0 |
| RPL5 | -602.0 |
| U2AF1L4 | -586.0 |
| HNRNPK | -563.0 |
| WBP4 | -547.0 |
| POLR2C | -541.0 |
| NUP160 | -518.0 |
| CSTF1 | -499.0 |
| PSMA1 | -477.0 |
| FIP1L1 | -408.0 |
| SYF2 | -376.0 |
| RPL41 | -362.0 |
| RPL37 | -341.0 |
| RPSA | -319.0 |
| PSMB8 | -260.0 |
| DDX5 | -242.0 |
| UBA52 | -167.0 |
| POLR2L | -110.0 |
| WDR75 | -105.0 |
| IK | -90.0 |
| LENG1 | -82.0 |
| PPIL4 | -37.0 |
| CPSF6 | 39.0 |
| TNKS1BP1 | 89.0 |
| DDX42 | 107.0 |
| RPS10 | 170.0 |
| FAM32A | 216.0 |
| PRPF40A | 263.0 |
| NXT1 | 273.0 |
| NUP37 | 339.0 |
| RPL27 | 366.0 |
| DHX35 | 367.0 |
| FAM98B | 372.0 |
| RPL37A | 393.0 |
| THUMPD1 | 422.0 |
| PSMB10 | 447.0 |
| CNOT10 | 488.0 |
| CLP1 | 507.0 |
| TRMT61B | 514.0 |
| RPS11 | 572.0 |
| TRMU | 713.0 |
| SRSF1 | 738.0 |
| PRPF6 | 800.0 |
| ERCC2 | 803.0 |
| RPL27A | 807.0 |
| RPS15A | 825.0 |
| PSMD12 | 901.0 |
| MTERF4 | 911.0 |
| CPSF3 | 915.0 |
| SMN1 | 933.5 |
| SMN2 | 933.5 |
| SEC13 | 959.0 |
| SDE2 | 988.0 |
| PRPF8 | 1029.0 |
| RTCB | 1048.0 |
| NCL | 1123.0 |
| CPSF7 | 1188.0 |
| PSMD14 | 1213.0 |
| SF1 | 1242.0 |
| PPIG | 1280.0 |
| CSNK1E | 1281.0 |
| SUPT5H | 1305.0 |
| GAR1 | 1307.0 |
| RPL18 | 1337.0 |
| CASC3 | 1346.0 |
| RPS14 | 1389.0 |
| RBM7 | 1448.0 |
| SAP18 | 1462.0 |
| CSNK1D | 1496.0 |
| ZNF830 | 1501.0 |
| MFAP1 | 1567.0 |
| EPRS1 | 1578.0 |
| U2AF2 | 1614.0 |
| MAPK11 | 1621.0 |
| POLR2E | 1649.0 |
| NUP62 | 1710.0 |
| DDX20 | 1718.0 |
| SEM1 | 1794.0 |
| RPS27A | 1846.0 |
| GCFC2 | 1864.0 |
| RPS19 | 1922.0 |
| C9orf78 | 1951.0 |
| SNRPE | 1962.0 |
| SF3B1 | 1990.0 |
| NCBP2 | 2018.0 |
| SF3B3 | 2027.0 |
| PCBP1 | 2046.0 |
| HSPA1A | 2049.0 |
| TRMT11 | 2070.0 |
| PTBP1 | 2102.0 |
| ETF1 | 2142.0 |
| MAGOHB | 2146.0 |
| BUD23 | 2152.0 |
| PRPF31 | 2182.0 |
| PSMC5 | 2183.0 |
| RAE1 | 2192.0 |
| TRMT5 | 2226.0 |
| PSMD8 | 2235.0 |
| SMG7 | 2288.0 |
| TBL3 | 2550.0 |
| RIOK3 | 2623.0 |
| THOC5 | 2643.0 |
| SNRPG | 2687.0 |
| SRSF4 | 2689.0 |
| MTREX | 2694.0 |
| RPL17 | 2714.0 |
| SRSF3 | 2727.0 |
| NUP93 | 2760.0 |
| SMNDC1 | 2776.0 |
| CACTIN | 2780.0 |
| UPF2 | 2789.0 |
| EDC3 | 2805.0 |
| DUS2 | 2814.0 |
| EIF4B | 2841.0 |
| NDC1 | 2860.0 |
| RPL13 | 2891.0 |
| PNRC2 | 2917.0 |
| RPS25 | 2926.0 |
| RANBP2 | 3016.0 |
| SRRT | 3040.0 |
| MAGOH | 3080.0 |
| RPL23A | 3129.0 |
| POLDIP3 | 3251.0 |
| SRSF11 | 3315.0 |
| TNFSF13 | 3351.0 |
| RPS27L | 3361.0 |
| RIOK1 | 3381.0 |
| DIS3 | 3384.0 |
| EBNA1BP2 | 3392.0 |
| ZFP36 | 3463.0 |
| ERI1 | 3480.0 |
| SNRPD3 | 3490.0 |
| RPL35 | 3496.0 |
| WDR77 | 3502.0 |
| HNRNPU | 3503.0 |
| RPS29 | 3531.0 |
| RPL3 | 3541.0 |
| ZCRB1 | 3571.0 |
| MRM1 | 3660.0 |
| QTRT1 | 3669.0 |
| RPL10L | 3682.0 |
| APOBEC3A | 3689.0 |
| NSUN4 | 3718.0 |
| SNRPC | 3727.0 |
| PRPF4 | 3784.0 |
| PAIP1 | 3830.0 |
| EIF4A2 | 3982.0 |
| NUP153 | 4025.0 |
| RIOK2 | 4030.0 |
| FTSJ3 | 4140.0 |
| XAB2 | 4144.0 |
| UTP25 | 4149.0 |
| NUP54 | 4170.0 |
| AAAS | 4254.0 |
| GEMIN4 | 4281.0 |
| ZBTB8OS | 4282.0 |
| GNL3 | 4287.0 |
| PAN2 | 4343.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| PRKRIP1 | 4474.0 |
| RRP1 | 4479.0 |
| PPIH | 4543.0 |
| CPSF1 | 4549.0 |
| NUDT21 | 4590.0 |
| PRORP | 4601.0 |
| DCAF13 | 4623.0 |
| DDX39A | 4662.0 |
| RPL12 | 4672.0 |
| AKT1 | 4674.0 |
| RPS2 | 4762.0 |
| RPL35A | 4775.0 |
| SARNP | 4846.0 |
| RPP21 | 4859.0 |
| POLR2I | 4862.0 |
| PSMB4 | 4971.0 |
| DIMT1 | 5009.0 |
| ZFP36L1 | 5017.0 |
| GEMIN6 | 5069.0 |
| TP53RK | 5080.0 |
| HNRNPF | 5109.0 |
| METTL14 | 5126.0 |
| RPL15 | 5129.0 |
| EXOSC5 | 5141.0 |
| TRMT10A | 5167.0 |
| PSMF1 | 5221.0 |
| LSM7 | 5231.0 |
| EXOSC8 | 5240.0 |
| RPL30 | 5251.0 |
| TSR3 | 5289.0 |
| GTF2H3 | 5295.0 |
| PSMD7 | 5305.0 |
| TRMT112 | 5339.0 |
| NUP58 | 5365.0 |
| GEMIN7 | 5524.0 |
| RPL13A | 5555.5 |
| GTF2H5 | 5585.0 |
| EXOSC1 | 5589.0 |
| RPS15 | 5609.0 |
| NHP2 | 5624.0 |
| CDC40 | 5642.0 |
| SEH1L | 5647.0 |
| POP5 | 5650.0 |
| RPS27 | 5679.0 |
| YWHAZ | 5701.0 |
| EIF4A1 | 5726.0 |
| DCPS | 5745.0 |
| PPWD1 | 5750.0 |
| SNRPA | 5751.0 |
| PSMB2 | 5803.0 |
| RPL36 | 5850.0 |
| PSMB7 | 5858.0 |
| GSPT1 | 5989.0 |
| CNOT11 | 5993.0 |
| UTP15 | 6059.0 |
| SF3B2 | 6090.0 |
| NOL9 | 6100.0 |
| LSM10 | 6106.0 |
| WDR46 | 6119.0 |
| USP39 | 6140.0 |
| RPL11 | 6162.0 |
| NXF1 | 6183.0 |
| EXOSC6 | 6261.0 |
| HNRNPC | 6281.0 |
| RPL7 | 6313.0 |
| RPL4 | 6383.0 |
| GTF2H4 | 6387.0 |
| RPL23 | 6429.0 |
| IMP3 | 6459.0 |
| LSM6 | 6490.0 |
| PSMA8 | 6502.0 |
| FYTTD1 | 6538.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| RPS3 | 6659.0 |
| RPLP1 | 6672.0 |
| PDCD11 | 6680.0 |
| RPL19 | 6685.0 |
| UBC | 6700.0 |
| RPL39L | 6704.0 |
| RPS28 | 6787.0 |
| RNMT | 6823.0 |
| TYW1 | 6850.0 |
| RPL26L1 | 6861.0 |
| ADAR | 6869.0 |
| ADARB1 | 6876.0 |
| ZNF473 | 6883.0 |
| RPS18 | 6884.0 |
| CDC5L | 6901.0 |
| SNRNP35 | 6907.0 |
| PSMA6 | 6984.0 |
| RBM39 | 6995.0 |
| IGF2BP2 | 7016.0 |
| PRKCD | 7089.0 |
| RPL28 | 7094.0 |
| TSEN34 | 7130.0 |
| EIF4G1 | 7185.0 |
| THOC6 | 7219.0 |
| UPF3A | 7329.0 |
| ADAT2 | 7372.0 |
| SLBP | 7374.0 |
| NUP155 | 7411.0 |
| UPF1 | 7420.0 |
| IGF2BP1 | 7467.0 |
| RPL22L1 | 7521.0 |
| PSMA4 | 7568.0 |
| TRMT61A | 7577.0 |
| UBB | 7594.0 |
| RPS8 | 7606.0 |
| SNRPA1 | 7675.0 |
| SRSF7 | 7689.0 |
| DDX21 | 7690.0 |
| DDX41 | 7721.0 |
| CWC15 | 7725.0 |
| THOC3 | 7729.5 |
| HSPA8 | 7737.0 |
| ZMAT2 | 7856.0 |
| SNRNP25 | 7876.0 |
| PATL1 | 7934.0 |
| TRMT1 | 7949.0 |
| TRA2B | 7992.0 |
| PSMB3 | 8017.0 |
| RPL6 | 8034.0 |
| CWC25 | 8038.0 |
| A1CF | 8073.0 |
| SNUPN | 8127.0 |
| CCDC12 | 8169.0 |
| SNRPB2 | 8291.0 |
| ANP32A | 8312.0 |
| POLR2D | 8323.0 |
| SNRPF | 8331.0 |
| EXOSC9 | 8477.0 |
| KRR1 | 8560.0 |
| EIF4E | 8682.0 |
| SET | 8685.0 |
| SMG9 | 8701.0 |
| POLR2F | 8864.0 |
| RPS5 | 8900.0 |
| SRSF10 | 8934.0 |
| WBP11 | 8945.0 |
| POP7 | 8958.0 |
| RPLP0 | 8964.0 |
| POLR2G | 9208.0 |
| RPS9 | 9248.0 |
| RPL3L | 9264.0 |
| RPS24 | 9270.0 |
| RPL18A | 9478.0 |
| CTU2 | 9497.0 |
| PCBP2 | 9546.0 |
| PSMA7 | 9563.0 |
| ADAT1 | 9574.0 |
| PSME1 | 9765.0 |
| APOBEC3B | 9899.0 |
| RPLP2 | 9904.0 |
| RRP9 | 9962.0 |
| SF3B6 | 10032.0 |
| RPL7A | 10044.0 |
| APOBEC1 | 10562.0 |
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
| 1146 | |
|---|---|
| set | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA |
| setSize | 263 |
| pANOVA | 1.82e-05 |
| s.dist | -0.153 |
| p.adjustANOVA | 0.00299 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A3 | -9788 |
| DDX39B | -9566 |
| DHX16 | -9334 |
| SNRNP200 | -9279 |
| TCERG1 | -9231 |
| GPATCH1 | -9155 |
| AQR | -9124 |
| POM121C | -9098 |
| SMU1 | -9068 |
| PPIE | -8917 |
| SNU13 | -8840 |
| NSRP1 | -8755 |
| BUD31 | -8705 |
| HNRNPH1 | -8685 |
| DHX38 | -8620 |
| CHERP | -8573 |
| YJU2 | -8567 |
| WDR70 | -8530 |
| CPSF2 | -8474 |
| PABPN1 | -8466 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A3 | -9788.0 |
| DDX39B | -9566.0 |
| DHX16 | -9334.0 |
| SNRNP200 | -9279.0 |
| TCERG1 | -9231.0 |
| GPATCH1 | -9155.0 |
| AQR | -9124.0 |
| POM121C | -9098.0 |
| SMU1 | -9068.0 |
| PPIE | -8917.0 |
| SNU13 | -8840.0 |
| NSRP1 | -8755.0 |
| BUD31 | -8705.0 |
| HNRNPH1 | -8685.0 |
| DHX38 | -8620.0 |
| CHERP | -8573.0 |
| YJU2 | -8567.0 |
| WDR70 | -8530.0 |
| CPSF2 | -8474.0 |
| PABPN1 | -8466.0 |
| CWC22 | -8401.0 |
| POM121 | -8267.0 |
| SNRNP70 | -8255.0 |
| SLU7 | -8211.0 |
| SNRNP48 | -8100.0 |
| RBM8A | -7974.0 |
| RBM5 | -7948.0 |
| PPP1R8 | -7943.0 |
| SF3B5 | -7928.0 |
| RNPC3 | -7642.0 |
| SRSF9 | -7628.0 |
| SF3A3 | -7579.0 |
| POLR2A | -7443.0 |
| GLE1 | -7413.0 |
| PRPF3 | -7409.0 |
| SNIP1 | -7405.0 |
| LUC7L3 | -7296.0 |
| NUP214 | -7186.0 |
| CPSF4 | -7145.0 |
| SNRPB | -7144.0 |
| BUD13 | -7079.0 |
| PPIL3 | -6952.0 |
| U2SURP | -6931.0 |
| NUP88 | -6865.0 |
| CWF19L2 | -6798.0 |
| NCBP1 | -6659.0 |
| SRSF2 | -6648.0 |
| SNRPD2 | -6623.0 |
| NUP42 | -6551.0 |
| ZMAT5 | -6486.0 |
| SUGP1 | -6448.0 |
| TFIP11 | -6393.0 |
| POLR2K | -6386.0 |
| LSM2 | -6210.0 |
| SRRM1 | -6188.0 |
| RNPS1 | -5988.0 |
| THOC7 | -5974.0 |
| SNRNP40 | -5897.0 |
| BCAS2 | -5871.0 |
| PRPF18 | -5822.0 |
| NUP210 | -5812.0 |
| ALYREF | -5793.0 |
| CCAR1 | -5744.0 |
| PNN | -5581.0 |
| RBM22 | -5571.0 |
| TPR | -5490.0 |
| PRCC | -5481.0 |
| SF3B4 | -5403.0 |
| CSTF3 | -5380.0 |
| PCF11 | -5372.0 |
| CTNNBL1 | -5340.0 |
| CHTOP | -5318.0 |
| PRPF38A | -5034.0 |
| LSM3 | -4982.0 |
| LSM8 | -4946.0 |
| RBM17 | -4872.0 |
| METTL3 | -4781.0 |
| CRNKL1 | -4726.0 |
| SF3A2 | -4651.0 |
| POLR2J | -4576.0 |
| PPIL1 | -4564.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| ACIN1 | -4440.0 |
| NUP85 | -4358.0 |
| THOC1 | -4354.0 |
| PRPF19 | -4349.0 |
| NUP98 | -4330.0 |
| DNAJC8 | -4175.0 |
| FUS | -4173.0 |
| ISY1 | -4170.0 |
| POLR2B | -4142.0 |
| LSM4 | -3953.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| SRSF12 | -3860.0 |
| WDR33 | -3854.0 |
| SRRM2 | -3777.0 |
| SRSF5 | -3776.0 |
| PUF60 | -3724.0 |
| DHX9 | -3722.0 |
| LSM5 | -3706.0 |
| DDX23 | -3700.0 |
| SRSF6 | -3471.0 |
| NUP133 | -3446.0 |
| GTF2F1 | -3422.0 |
| RBM42 | -3380.0 |
| UBL5 | -3297.0 |
| SRSF8 | -3290.0 |
| YBX1 | -3218.0 |
| SNRPN | -3030.0 |
| DDX46 | -2992.0 |
| HNRNPR | -2852.0 |
| NUP188 | -2837.0 |
| HNRNPA1 | -2749.0 |
| ZC3H11A | -2721.0 |
| NUP205 | -2593.0 |
| RBM25 | -2456.0 |
| CSTF2T | -2324.0 |
| SYMPK | -2309.0 |
| SNRNP27 | -2216.0 |
| SART1 | -2165.0 |
| DHX8 | -1818.0 |
| PPIL2 | -1788.0 |
| SNRPD1 | -1764.0 |
| HNRNPM | -1739.0 |
| PHF5A | -1705.0 |
| HNRNPA2B1 | -1681.0 |
| SNW1 | -1658.0 |
| GTF2F2 | -1647.0 |
| EFTUD2 | -1614.0 |
| POLR2H | -1463.0 |
| TXNL4A | -1415.0 |
| PAPOLA | -1301.0 |
| WTAP | -1237.0 |
| PDCD7 | -1150.0 |
| HNRNPA3 | -1141.0 |
| PLRG1 | -1130.0 |
| SF3A1 | -1025.0 |
| DHX15 | -922.0 |
| CWC27 | -851.0 |
| HNRNPD | -848.0 |
| HNRNPL | -818.0 |
| U2AF1L4 | -586.0 |
| HNRNPK | -563.0 |
| WBP4 | -547.0 |
| POLR2C | -541.0 |
| NUP160 | -518.0 |
| CSTF1 | -499.0 |
| FIP1L1 | -408.0 |
| SYF2 | -376.0 |
| DDX5 | -242.0 |
| POLR2L | -110.0 |
| IK | -90.0 |
| LENG1 | -82.0 |
| PPIL4 | -37.0 |
| CPSF6 | 39.0 |
| DDX42 | 107.0 |
| FAM32A | 216.0 |
| PRPF40A | 263.0 |
| NXT1 | 273.0 |
| NUP37 | 339.0 |
| DHX35 | 367.0 |
| CLP1 | 507.0 |
| SRSF1 | 738.0 |
| PRPF6 | 800.0 |
| CPSF3 | 915.0 |
| SEC13 | 959.0 |
| SDE2 | 988.0 |
| PRPF8 | 1029.0 |
| CPSF7 | 1188.0 |
| SF1 | 1242.0 |
| PPIG | 1280.0 |
| CASC3 | 1346.0 |
| RBM7 | 1448.0 |
| SAP18 | 1462.0 |
| ZNF830 | 1501.0 |
| MFAP1 | 1567.0 |
| U2AF2 | 1614.0 |
| POLR2E | 1649.0 |
| NUP62 | 1710.0 |
| GCFC2 | 1864.0 |
| C9orf78 | 1951.0 |
| SNRPE | 1962.0 |
| SF3B1 | 1990.0 |
| NCBP2 | 2018.0 |
| SF3B3 | 2027.0 |
| PCBP1 | 2046.0 |
| PTBP1 | 2102.0 |
| MAGOHB | 2146.0 |
| PRPF31 | 2182.0 |
| RAE1 | 2192.0 |
| THOC5 | 2643.0 |
| SNRPG | 2687.0 |
| SRSF4 | 2689.0 |
| MTREX | 2694.0 |
| SRSF3 | 2727.0 |
| NUP93 | 2760.0 |
| SMNDC1 | 2776.0 |
| CACTIN | 2780.0 |
| NDC1 | 2860.0 |
| RANBP2 | 3016.0 |
| SRRT | 3040.0 |
| MAGOH | 3080.0 |
| POLDIP3 | 3251.0 |
| SRSF11 | 3315.0 |
| SNRPD3 | 3490.0 |
| HNRNPU | 3503.0 |
| ZCRB1 | 3571.0 |
| SNRPC | 3727.0 |
| PRPF4 | 3784.0 |
| NUP153 | 4025.0 |
| XAB2 | 4144.0 |
| NUP54 | 4170.0 |
| AAAS | 4254.0 |
| PRKRIP1 | 4474.0 |
| PPIH | 4543.0 |
| CPSF1 | 4549.0 |
| NUDT21 | 4590.0 |
| DDX39A | 4662.0 |
| SARNP | 4846.0 |
| POLR2I | 4862.0 |
| HNRNPF | 5109.0 |
| METTL14 | 5126.0 |
| LSM7 | 5231.0 |
| NUP58 | 5365.0 |
| CDC40 | 5642.0 |
| SEH1L | 5647.0 |
| PPWD1 | 5750.0 |
| SNRPA | 5751.0 |
| SF3B2 | 6090.0 |
| USP39 | 6140.0 |
| NXF1 | 6183.0 |
| HNRNPC | 6281.0 |
| LSM6 | 6490.0 |
| FYTTD1 | 6538.0 |
| CDC5L | 6901.0 |
| SNRNP35 | 6907.0 |
| RBM39 | 6995.0 |
| THOC6 | 7219.0 |
| SLBP | 7374.0 |
| NUP155 | 7411.0 |
| SNRPA1 | 7675.0 |
| SRSF7 | 7689.0 |
| DDX41 | 7721.0 |
| CWC15 | 7725.0 |
| THOC3 | 7729.5 |
| HSPA8 | 7737.0 |
| ZMAT2 | 7856.0 |
| SNRNP25 | 7876.0 |
| TRA2B | 7992.0 |
| CWC25 | 8038.0 |
| CCDC12 | 8169.0 |
| SNRPB2 | 8291.0 |
| POLR2D | 8323.0 |
| SNRPF | 8331.0 |
| EIF4E | 8682.0 |
| POLR2F | 8864.0 |
| SRSF10 | 8934.0 |
| WBP11 | 8945.0 |
| POLR2G | 9208.0 |
| PCBP2 | 9546.0 |
| SF3B6 | 10032.0 |
REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
| 1082 | |
|---|---|
| set | REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE |
| setSize | 125 |
| pANOVA | 2.71e-05 |
| s.dist | 0.217 |
| p.adjustANOVA | 0.00396 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| KRT16 | 11459 |
| SPRR2E | 11441 |
| LCE4A | 11411 |
| LCE3D | 11143 |
| LIPN | 11061 |
| KRT80 | 10981 |
| KRT14 | 10942 |
| KRT31 | 10784 |
| DSG4 | 10774 |
| KRT13 | 10770 |
| KRT32 | 10757 |
| KRT2 | 10708 |
| KRT20 | 10595 |
| CDSN | 10570 |
| KRT8 | 10480 |
| SPRR1B | 10465 |
| KRT23 | 10425 |
| PI3 | 10310 |
| LCE1C | 10305 |
| KRT24 | 10051 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| KRT16 | 11459 |
| SPRR2E | 11441 |
| LCE4A | 11411 |
| LCE3D | 11143 |
| LIPN | 11061 |
| KRT80 | 10981 |
| KRT14 | 10942 |
| KRT31 | 10784 |
| DSG4 | 10774 |
| KRT13 | 10770 |
| KRT32 | 10757 |
| KRT2 | 10708 |
| KRT20 | 10595 |
| CDSN | 10570 |
| KRT8 | 10480 |
| SPRR1B | 10465 |
| KRT23 | 10425 |
| PI3 | 10310 |
| LCE1C | 10305 |
| KRT24 | 10051 |
| KRT3 | 9980 |
| LCE3A | 9928 |
| KRT78 | 9667 |
| KRT18 | 9618 |
| LCE2A | 9513 |
| IVL | 9424 |
| KRT76 | 9394 |
| KRT6A | 9356 |
| KRT83 | 9327 |
| KRT5 | 9228 |
| KRT74 | 9190 |
| RPTN | 8839 |
| SPINK5 | 8763 |
| PRSS8 | 8717 |
| SPRR3 | 8681 |
| KAZN | 8550 |
| TGM5 | 8471 |
| SPINK9 | 8439 |
| ST14 | 7991 |
| KRT17 | 7897 |
| EVPL | 7863 |
| DSG1 | 7819 |
| KRT9 | 7746 |
| PCSK6 | 7678 |
| KRT34 | 7585 |
| KRT79 | 7575 |
| LELP1 | 7416 |
| FURIN | 7240 |
| KRT25 | 7197 |
| KRT7 | 7162 |
| KRT1 | 7101 |
| KLK12 | 7087 |
| KRT38 | 7043 |
| KRT40 | 6970 |
| LCE6A | 6693 |
| KRT82 | 6361 |
| PKP3 | 6320 |
| KRT28 | 5810 |
| PERP | 5738 |
| KRT37 | 5578 |
| SPRR1A | 5570 |
| DSG3 | 5522 |
| LCE3E | 5472 |
| JUP | 5024 |
| KRT71 | 5013 |
| SPRR2G | 5000 |
| KRT72 | 4813 |
| KRT4 | 4263 |
| KRT15 | 4262 |
| LCE3B | 4204 |
| KRT73 | 4201 |
| KRT35 | 3684 |
| KRT19 | 3180 |
| LCE2D | 3089 |
| LIPJ | 2824 |
| SPRR2F | 2394 |
| KRT81 | 1658 |
| LCE1A | 1598 |
| KLK8 | 1177 |
| KRT33B | 977 |
| KRT12 | 469 |
| DSG2 | 220 |
| KLK13 | 69 |
| KRT10 | -795 |
| KLK5 | -868 |
| KRT77 | -898 |
| LCE1B | -1088 |
| KRT75 | -1360 |
| KRT26 | -1487 |
| SPRR2A | -2009 |
| TGM1 | -2458 |
| CASP14 | -2646 |
| KRT85 | -2758 |
| CAPN1 | -2768 |
| PPL | -3126 |
| DSP | -3279 |
| PKP4 | -3389 |
| KLK14 | -3497 |
| KRT86 | -5820 |
| CELA2A | -6063 |
| FLG | -6381 |
| SPINK6 | -6455 |
| PKP2 | -6745 |
| LIPK | -6846 |
| LCE1F | -6991 |
| LCE1E | -7262 |
| SPRR2D | -7277 |
| TCHH | -7381 |
| PKP1 | -7582 |
| KRT36 | -7603 |
| CSTA | -7732 |
| KRT84 | -8057 |
| LCE5A | -8252 |
| KRT27 | -8333 |
| DSC2 | -8380 |
| LCE2B | -8454 |
| DSC1 | -8825 |
| LIPM | -8866 |
| KRT33A | -8895 |
| CAPNS1 | -8896 |
| LCE2C | -8992 |
| KRT6C | -9007 |
| KRT39 | -9087 |
| KRT6B | -9247 |
| DSC3 | -10016 |
REACTOME_MITOTIC_PROMETAPHASE
| 1094 | |
|---|---|
| set | REACTOME_MITOTIC_PROMETAPHASE |
| setSize | 194 |
| pANOVA | 2.96e-05 |
| s.dist | -0.174 |
| p.adjustANOVA | 0.00396 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| TUBA1C | -8675 |
| CENPH | -8616 |
| TUBG2 | -8420 |
| NCAPD2 | -8303 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| NDEL1 | -8074 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| TUBA1C | -8675 |
| CENPH | -8616 |
| TUBG2 | -8420 |
| NCAPD2 | -8303 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| NDEL1 | -8074 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| KIF2C | -7337 |
| ODF2 | -7061 |
| CCNB2 | -6945 |
| NUMA1 | -6884 |
| CENPC | -6867 |
| PLK1 | -6633 |
| PPP1CC | -6627 |
| TUBA4A | -6626 |
| SMC2 | -6571 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| TUBB2B | -6314 |
| CEP72 | -6174 |
| CENPF | -6110 |
| CSNK2B | -6080 |
| ZW10 | -6072 |
| MAD2L1 | -6059 |
| HAUS5 | -6025 |
| TUBB2A | -5979 |
| TUBGCP5 | -5800 |
| CLIP1 | -5755 |
| TUBGCP6 | -5669 |
| CLASP1 | -5346 |
| PPP2R5E | -5142 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CEP43 | -4973 |
| SDCCAG8 | -4735 |
| DYNC1LI2 | -4730 |
| KIF2A | -4638 |
| TUBA1B | -4624 |
| PCNT | -4617 |
| NUP107 | -4561 |
| CEP250 | -4503 |
| NUP85 | -4358 |
| XPO1 | -4345 |
| CLASP2 | -4343 |
| NUP98 | -4330 |
| CEP41 | -4178 |
| TUBA8 | -4032 |
| WAPL | -3947 |
| NUP43 | -3906 |
| CENPA | -3845 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| KNTC1 | -3683 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| NUF2 | -3541 |
| NUP133 | -3446 |
| SPDL1 | -3370 |
| MAD1L1 | -3364 |
| AKAP9 | -3238 |
| RAD21 | -3080 |
| ZWILCH | -3078 |
| RCC2 | -2861 |
| ITGB3BP | -2777 |
| CENPQ | -2767 |
| CEP70 | -2717 |
| B9D2 | -2628 |
| RANGAP1 | -2606 |
| PAFAH1B1 | -2571 |
| BIRC5 | -2354 |
| CDK1 | -2219 |
| DYNC1I1 | -2088 |
| CENPT | -2076 |
| PDS5B | -2067 |
| HAUS6 | -2029 |
| CSNK2A2 | -2019 |
| CEP290 | -2002 |
| TUBGCP3 | -1900 |
| TUBA1A | -1819 |
| CDK5RAP2 | -1570 |
| CCP110 | -1489 |
| SGO1 | -1080 |
| PDS5A | -1046 |
| CDCA8 | -916 |
| NCAPG | -857 |
| NEK7 | -599 |
| NCAPH | -562 |
| CENPP | -551 |
| YWHAE | -521 |
| NUP160 | -518 |
| DCTN1 | -338 |
| DSN1 | -331 |
| TUBGCP2 | -268 |
| NEK2 | -182 |
| STAG1 | -147 |
| AHCTF1 | -75 |
| KIF2B | -57 |
| CEP78 | 13 |
| YWHAG | 115 |
| TUBB | 261 |
| SKA2 | 265 |
| NUP37 | 339 |
| BUB1B | 349 |
| EML4 | 552 |
| BUB1 | 660 |
| NEDD1 | 779 |
| SMC4 | 787 |
| NSL1 | 804 |
| CENPS | 874 |
| SEC13 | 959 |
| KIF18A | 960 |
| HAUS3 | 961 |
| NME7 | 1011 |
| CENPJ | 1016 |
| TUBB1 | 1069 |
| SMC3 | 1172 |
| CSNK1E | 1281 |
| CENPM | 1294 |
| SPC25 | 1348 |
| PPP2R5A | 1480 |
| CSNK1D | 1496 |
| CENPN | 1892 |
| MIS12 | 1902 |
| CSNK2A1 | 2040 |
| SSNA1 | 2103 |
| ACTR1A | 2220 |
| CENPE | 2236 |
| SFI1 | 2352 |
| PPP2R5C | 2434 |
| MAPRE1 | 2575 |
| ALMS1 | 2804 |
| RANBP2 | 3016 |
| TUBA3C | 3214 |
| SKA1 | 3245 |
| PPP2CB | 3417 |
| NUDC | 3440 |
| CENPK | 3476 |
| NEK9 | 3481 |
| CENPL | 3515 |
| TUBB6 | 3539 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| TUBB4A | 3612 |
| PRKAR2B | 4071 |
| PPP2R5B | 4232 |
| PMF1 | 4398 |
| HSP90AA1 | 4414 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| HAUS2 | 4581 |
| CDCA5 | 4721 |
| HAUS4 | 4825 |
| AURKB | 4877 |
| SPC24 | 5022 |
| NEK6 | 5041 |
| HAUS1 | 5311 |
| TAOK1 | 5424 |
| SEH1L | 5647 |
| RPS27 | 5679 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| NDC80 | 6086 |
| PRKACA | 6168 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| KNL1 | 6545 |
| MZT2B | 6651 |
| PPP2R5D | 6733 |
| DYNC1LI1 | 6830 |
| CENPU | 6916 |
| CDC20 | 7234 |
| BUB3 | 7623 |
| NINL | 9656 |
| TUBB8 | 11325 |
REACTOME_CELL_CYCLE_CHECKPOINTS
| 1120 | |
|---|---|
| set | REACTOME_CELL_CYCLE_CHECKPOINTS |
| setSize | 284 |
| pANOVA | 3.14e-05 |
| s.dist | -0.144 |
| p.adjustANOVA | 0.00396 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CHEK1 | -9546.0 |
| UBE2C | -9474.0 |
| INCENP | -9447.0 |
| H2BC7 | -9424.5 |
| PPP2R1B | -9252.0 |
| PHF20 | -8977.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| ANAPC5 | -8661.0 |
| CENPH | -8616.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| PSMB11 | -8512.0 |
| NSD2 | -8330.0 |
| H2BC13 | -8199.0 |
| MCM6 | -8182.0 |
| H4C16 | -8109.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CHEK1 | -9546.0 |
| UBE2C | -9474.0 |
| INCENP | -9447.0 |
| H2BC7 | -9424.5 |
| PPP2R1B | -9252.0 |
| PHF20 | -8977.0 |
| CCNB1 | -8935.0 |
| SGO2 | -8909.0 |
| PSMD2 | -8887.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| ANAPC5 | -8661.0 |
| CENPH | -8616.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| PSMB11 | -8512.0 |
| NSD2 | -8330.0 |
| H2BC13 | -8199.0 |
| MCM6 | -8182.0 |
| H4C16 | -8109.0 |
| NDEL1 | -8074.0 |
| CDC6 | -8067.0 |
| YWHAB | -8002.0 |
| PSMC1 | -7848.0 |
| ABRAXAS1 | -7840.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| RPA1 | -7755.0 |
| CENPO | -7707.0 |
| H2AX | -7648.0 |
| CKAP5 | -7526.0 |
| DYNLL2 | -7477.0 |
| TOPBP1 | -7459.0 |
| ZWINT | -7442.0 |
| PSMD13 | -7362.0 |
| KIF2C | -7337.0 |
| ORC2 | -7207.0 |
| MCM10 | -7149.0 |
| CDKN1B | -6954.0 |
| CCNB2 | -6945.0 |
| CENPC | -6867.0 |
| CDC7 | -6856.0 |
| TOP3A | -6676.0 |
| CDC25A | -6647.0 |
| PLK1 | -6633.0 |
| PPP1CC | -6627.0 |
| PSMD3 | -6608.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| BRCA1 | -6477.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| PSMD4 | -6409.0 |
| PSMB5 | -6339.0 |
| ORC6 | -6177.0 |
| CENPF | -6110.0 |
| ZW10 | -6072.0 |
| MAD2L1 | -6059.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| ANAPC7 | -5789.0 |
| CLIP1 | -5755.0 |
| H2BC15 | -5694.0 |
| RNF168 | -5628.0 |
| H3-4 | -5447.0 |
| YWHAQ | -5428.0 |
| ORC1 | -5405.0 |
| CLASP1 | -5346.0 |
| H2BC6 | -5295.0 |
| PSMC3 | -5262.0 |
| ATM | -5218.0 |
| PPP2R5E | -5142.0 |
| DYNC1I2 | -5131.0 |
| H2BC4 | -5066.0 |
| PSME4 | -5053.0 |
| PSMA5 | -4888.0 |
| CDC23 | -4806.0 |
| UBE2V2 | -4803.0 |
| CDC27 | -4761.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| CDKN2A | -4700.0 |
| RFC5 | -4673.0 |
| KIF2A | -4638.0 |
| NUP107 | -4561.0 |
| H4C6 | -4534.0 |
| COP1 | -4515.0 |
| CDC25C | -4507.0 |
| RAD1 | -4483.0 |
| RNF8 | -4361.0 |
| NUP85 | -4358.0 |
| UBE2D1 | -4355.0 |
| XPO1 | -4345.0 |
| CLASP2 | -4343.0 |
| NUP98 | -4330.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| GTSE1 | -4241.0 |
| H2BC17 | -4192.0 |
| UBE2E1 | -4108.0 |
| WRN | -4104.0 |
| RAD50 | -4035.0 |
| PSMD1 | -3979.0 |
| NUP43 | -3906.0 |
| H4C4 | -3867.0 |
| CENPA | -3845.0 |
| KNTC1 | -3683.0 |
| ANAPC2 | -3617.0 |
| H2BC26 | -3582.0 |
| NDE1 | -3562.0 |
| DYNLL1 | -3550.0 |
| NUF2 | -3541.0 |
| NUP133 | -3446.0 |
| SPDL1 | -3370.0 |
| MAD1L1 | -3364.0 |
| ANAPC15 | -3203.0 |
| CDKN1A | -3164.0 |
| HUS1 | -3130.0 |
| PSMC4 | -3089.0 |
| ZWILCH | -3078.0 |
| ORC5 | -3040.0 |
| RCC2 | -2861.0 |
| PSMB1 | -2799.0 |
| ITGB3BP | -2777.0 |
| CENPQ | -2767.0 |
| B9D2 | -2628.0 |
| RANGAP1 | -2606.0 |
| PAFAH1B1 | -2571.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| BIRC5 | -2354.0 |
| CDK1 | -2219.0 |
| PSMC6 | -2126.0 |
| BABAM1 | -2123.0 |
| DYNC1I1 | -2088.0 |
| CENPT | -2076.0 |
| CLSPN | -2005.0 |
| KAT5 | -1955.0 |
| ANAPC16 | -1795.0 |
| PSMB9 | -1684.0 |
| ATR | -1677.0 |
| PSMA3 | -1391.0 |
| PSME3 | -1153.0 |
| SGO1 | -1080.0 |
| RMI1 | -1065.0 |
| H2BC8 | -1029.0 |
| ANAPC11 | -1014.0 |
| CDCA8 | -916.0 |
| ATRIP | -702.0 |
| MCM7 | -690.0 |
| MCM4 | -651.0 |
| DBF4 | -610.0 |
| ORC3 | -561.0 |
| CENPP | -551.0 |
| TP53 | -548.0 |
| RAD17 | -530.0 |
| YWHAE | -521.0 |
| NUP160 | -518.0 |
| PCBP4 | -493.0 |
| PSMA1 | -477.0 |
| WEE1 | -335.0 |
| DSN1 | -331.0 |
| PSMB8 | -260.0 |
| UBA52 | -167.0 |
| MDC1 | -145.0 |
| AHCTF1 | -75.0 |
| KIF2B | -57.0 |
| DNA2 | -36.0 |
| RFC3 | -16.0 |
| MDM4 | 110.0 |
| YWHAG | 115.0 |
| SKA2 | 265.0 |
| NUP37 | 339.0 |
| BUB1B | 349.0 |
| PSMB10 | 447.0 |
| BUB1 | 660.0 |
| NSL1 | 804.0 |
| CENPS | 874.0 |
| H4C5 | 878.0 |
| PSMD12 | 901.0 |
| MCM8 | 954.0 |
| SEC13 | 959.0 |
| KIF18A | 960.0 |
| RFC4 | 973.0 |
| BABAM2 | 1018.0 |
| CDC16 | 1047.0 |
| RPA2 | 1210.0 |
| PSMD14 | 1213.0 |
| CENPM | 1294.0 |
| SPC25 | 1348.0 |
| PPP2R5A | 1480.0 |
| SEM1 | 1794.0 |
| RPS27A | 1846.0 |
| ORC4 | 1871.0 |
| CENPN | 1892.0 |
| MIS12 | 1902.0 |
| H2BC3 | 1920.0 |
| MCM3 | 2165.0 |
| PSMC5 | 2183.0 |
| PSMD8 | 2235.0 |
| CENPE | 2236.0 |
| EXO1 | 2396.0 |
| PPP2R5C | 2434.0 |
| MAPRE1 | 2575.0 |
| CDC45 | 2747.0 |
| H2BC1 | 2755.0 |
| RANBP2 | 3016.0 |
| BRIP1 | 3028.0 |
| TP53BP1 | 3107.0 |
| SKA1 | 3245.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| RMI2 | 3423.0 |
| NUDC | 3440.0 |
| UIMC1 | 3452.0 |
| CENPK | 3476.0 |
| NBN | 3478.0 |
| CENPL | 3515.0 |
| CDC26 | 3611.0 |
| PIAS4 | 3685.0 |
| BLM | 3894.0 |
| MCM5 | 3943.0 |
| PPP2R5B | 4232.0 |
| CCNE2 | 4280.0 |
| RFC2 | 4313.0 |
| CCNA2 | 4366.0 |
| PMF1 | 4398.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| RPA3 | 4481.0 |
| PKMYT1 | 4486.0 |
| MCM2 | 4670.0 |
| AURKB | 4877.0 |
| UBE2N | 4905.0 |
| PSMB4 | 4971.0 |
| SPC24 | 5022.0 |
| H4C3 | 5053.0 |
| CDK2 | 5165.0 |
| PSMF1 | 5221.0 |
| PSMD7 | 5305.0 |
| TAOK1 | 5424.0 |
| UBE2S | 5479.0 |
| MRE11 | 5531.0 |
| SEH1L | 5647.0 |
| RPS27 | 5679.0 |
| YWHAZ | 5701.0 |
| MDM2 | 5757.0 |
| RAD9A | 5759.0 |
| PSMB2 | 5803.0 |
| PSMB7 | 5858.0 |
| NDC80 | 6086.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| KNL1 | 6545.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| UBC | 6700.0 |
| PPP2R5D | 6733.0 |
| DYNC1LI1 | 6830.0 |
| RAD9B | 6859.0 |
| CENPU | 6916.0 |
| PSMA6 | 6984.0 |
| CDC20 | 7234.0 |
| H2BC21 | 7408.0 |
| CHEK2 | 7446.0 |
| CCNE1 | 7482.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| BUB3 | 7623.0 |
| YWHAH | 7669.0 |
| H2BC12 | 7676.0 |
| PSMB3 | 8017.0 |
| ZNF385A | 8625.0 |
| H4C1 | 8782.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| PSME1 | 9765.0 |
| H4C12 | 10027.0 |
| ANAPC1 | 10085.0 |
| H2BC14 | 10168.0 |
| SFN | 10357.0 |
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
| 1024 | |
|---|---|
| set | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION |
| setSize | 1356 |
| pANOVA | 3.51e-05 |
| s.dist | -0.067 |
| p.adjustANOVA | 0.00412 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| FCGR3B | -10434.0 |
| TUBA3D | -10323.0 |
| MYSM1 | -10286.0 |
| LHB | -10018.0 |
| FUCA2 | -9904.0 |
| AXIN2 | -9846.0 |
| TRAPPC6B | -9737.0 |
| GGCX | -9672.0 |
| GCNT4 | -9654.0 |
| BMP4 | -9595.0 |
| YY1 | -9556.0 |
| TAB1 | -9523.0 |
| RIPK1 | -9477.0 |
| UBE2C | -9474.0 |
| INCENP | -9447.0 |
| FOXL2 | -9444.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| SRD5A3 | -9415.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| FCGR3B | -10434.0 |
| TUBA3D | -10323.0 |
| MYSM1 | -10286.0 |
| LHB | -10018.0 |
| FUCA2 | -9904.0 |
| AXIN2 | -9846.0 |
| TRAPPC6B | -9737.0 |
| GGCX | -9672.0 |
| GCNT4 | -9654.0 |
| BMP4 | -9595.0 |
| YY1 | -9556.0 |
| TAB1 | -9523.0 |
| RIPK1 | -9477.0 |
| UBE2C | -9474.0 |
| INCENP | -9447.0 |
| FOXL2 | -9444.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| SRD5A3 | -9415.0 |
| GOLGA2 | -9392.0 |
| BTBD6 | -9376.0 |
| TFAP2C | -9348.0 |
| PHC1 | -9332.0 |
| HDAC1 | -9320.0 |
| TFAP2A | -9292.0 |
| USP24 | -9263.0 |
| PENK | -9233.0 |
| H2AC13 | -9229.0 |
| GATA3 | -9199.0 |
| UCHL1 | -9198.0 |
| METTL22 | -9171.0 |
| POM121C | -9098.0 |
| TUBB4B | -9023.0 |
| TOP2A | -9001.0 |
| GNE | -8983.0 |
| CUL2 | -8973.0 |
| USP20 | -8965.0 |
| COG5 | -8916.0 |
| APC | -8915.0 |
| ALPG | -8890.0 |
| USP19 | -8889.0 |
| PSMD2 | -8887.0 |
| NEU2 | -8874.0 |
| IGFBP1 | -8861.0 |
| TGFBR1 | -8839.0 |
| TRRAP | -8829.0 |
| WSB2 | -8824.0 |
| ALG8 | -8816.0 |
| NUDT14 | -8806.0 |
| HERC2 | -8765.0 |
| POMK | -8735.0 |
| FBXO10 | -8723.0 |
| PALB2 | -8722.0 |
| RAB2A | -8702.0 |
| ADAMTS1 | -8687.0 |
| SUZ12 | -8683.0 |
| ALG10B | -8680.0 |
| TUBA1C | -8675.0 |
| APOB | -8669.0 |
| DCAF4 | -8665.0 |
| SEC24C | -8660.0 |
| COG6 | -8613.0 |
| CHGB | -8612.0 |
| H4C13 | -8603.0 |
| PRSS41 | -8585.0 |
| THBS1 | -8580.0 |
| RPN2 | -8551.0 |
| DDX17 | -8532.0 |
| PSMB11 | -8512.0 |
| APOA2 | -8511.0 |
| IGFBP3 | -8484.0 |
| PIGS | -8478.0 |
| POMT1 | -8469.0 |
| CUL9 | -8462.0 |
| SELENOS | -8456.0 |
| PIGG | -8436.0 |
| MDGA1 | -8432.0 |
| COMMD2 | -8392.0 |
| NR4A2 | -8311.0 |
| NFRKB | -8306.0 |
| TUBA3E | -8293.0 |
| POM121 | -8267.0 |
| DCAF5 | -8257.0 |
| GBF1 | -8249.0 |
| H2BC13 | -8199.0 |
| APP | -8179.0 |
| IL6 | -8175.0 |
| EEF1AKMT2 | -8168.0 |
| TUSC3 | -8134.0 |
| TMEM115 | -8128.0 |
| H4C16 | -8109.0 |
| KLHL42 | -8085.0 |
| SPTA1 | -8080.0 |
| SAE1 | -8070.0 |
| PPARA | -8024.0 |
| KBTBD6 | -8021.0 |
| ULBP2 | -7999.0 |
| BECN1 | -7939.0 |
| FBXO11 | -7936.0 |
| USP42 | -7917.0 |
| NR3C2 | -7900.0 |
| NRN1L | -7899.0 |
| PSMC1 | -7848.0 |
| USP30 | -7843.0 |
| ABRAXAS1 | -7840.0 |
| RAET1L | -7836.0 |
| ZNF350 | -7830.0 |
| UBA6 | -7829.0 |
| LY6G6D | -7805.0 |
| H2BC5 | -7799.0 |
| PIGH | -7798.0 |
| ADAMTS5 | -7794.0 |
| UBE2F | -7780.0 |
| COMMD10 | -7776.0 |
| ASB8 | -7768.0 |
| RPA1 | -7755.0 |
| SEC24B | -7747.0 |
| HDAC2 | -7742.0 |
| SATB1 | -7713.0 |
| UBE2H | -7655.0 |
| SMAD2 | -7644.0 |
| UFD1 | -7620.0 |
| ENGASE | -7615.0 |
| APOL1 | -7558.0 |
| RAB15 | -7553.0 |
| RAD18 | -7491.0 |
| MFGE8 | -7481.0 |
| DYNLL2 | -7477.0 |
| PGR | -7470.0 |
| ATXN7 | -7462.0 |
| TRIM13 | -7461.0 |
| ACTL6A | -7457.0 |
| ALG11 | -7441.0 |
| COMMD3 | -7412.0 |
| RAB40B | -7390.0 |
| PSMD13 | -7362.0 |
| BTRC | -7343.0 |
| GORASP1 | -7335.0 |
| TDG | -7330.0 |
| AMTN | -7324.0 |
| UBE2R2 | -7297.0 |
| ADAMTS7 | -7282.0 |
| NRN1 | -7244.0 |
| CUL7 | -7243.0 |
| EEF2KMT | -7241.0 |
| XPC | -7228.0 |
| HDAC4 | -7226.0 |
| MUC12 | -7215.0 |
| TTLL5 | -7202.0 |
| F5 | -7200.0 |
| RABGGTA | -7199.0 |
| NUP214 | -7186.0 |
| UBD | -7147.0 |
| USP10 | -7138.0 |
| MARCHF6 | -7127.0 |
| EP300 | -7126.0 |
| RUVBL1 | -7114.0 |
| DNMT3A | -7110.0 |
| MCRS1 | -7069.0 |
| NCOR2 | -7068.0 |
| MEN1 | -7041.0 |
| SERPIND1 | -7009.0 |
| DHDDS | -6989.0 |
| ETFB | -6987.0 |
| ACTR5 | -6918.0 |
| TNKS2 | -6894.0 |
| KIN | -6876.0 |
| NUP88 | -6865.0 |
| BIRC3 | -6858.0 |
| NCOA1 | -6850.0 |
| HLTF | -6848.0 |
| RAB11A | -6808.0 |
| RAB2B | -6787.0 |
| FOXK1 | -6778.0 |
| RAB38 | -6771.0 |
| NAPG | -6750.0 |
| DCUN1D2 | -6738.0 |
| LMAN2 | -6735.0 |
| MGAT1 | -6716.0 |
| CBX8 | -6701.0 |
| UGGT1 | -6683.0 |
| DHPS | -6666.0 |
| CDC25A | -6647.0 |
| ALG9 | -6639.0 |
| TUBA4A | -6626.0 |
| MAN2A2 | -6624.0 |
| PSMD3 | -6608.0 |
| USP13 | -6601.0 |
| XRCC4 | -6593.0 |
| GPLD1 | -6588.0 |
| TTLL2 | -6585.0 |
| TRAPPC9 | -6567.0 |
| CCNF | -6564.0 |
| UBE2G1 | -6562.0 |
| DCTN3 | -6556.0 |
| RAB18 | -6554.0 |
| B3GNTL1 | -6553.0 |
| NUP42 | -6551.0 |
| RNF20 | -6536.0 |
| VASH1 | -6535.0 |
| TRAPPC10 | -6525.0 |
| TRIM27 | -6522.0 |
| SEC23A | -6518.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| ARRB2 | -6501.0 |
| PRKDC | -6492.0 |
| DCAF7 | -6491.0 |
| BRCA1 | -6477.0 |
| STAM | -6465.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| NR1I2 | -6423.0 |
| PEX14 | -6422.0 |
| RAB14 | -6417.0 |
| PSMD4 | -6409.0 |
| RAB7A | -6401.0 |
| RAB32 | -6396.0 |
| VCPKMT | -6380.0 |
| NGLY1 | -6355.0 |
| CDH2 | -6354.0 |
| NFKBIA | -6342.0 |
| PSMB5 | -6339.0 |
| TUBB2B | -6314.0 |
| RAB22A | -6301.0 |
| MUL1 | -6292.0 |
| CTR9 | -6284.0 |
| DPH5 | -6276.0 |
| C1GALT1 | -6255.0 |
| MGAT4A | -6224.0 |
| ASB14 | -6223.0 |
| DDOST | -6216.0 |
| RIPK2 | -6167.0 |
| PIGM | -6154.0 |
| PIGK | -6153.0 |
| ALG6 | -6144.0 |
| SPSB3 | -6119.0 |
| SEC31A | -6085.0 |
| CUL4A | -6079.0 |
| ASB13 | -6054.0 |
| COPG2 | -6052.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| SOCS5 | -5993.0 |
| CNIH3 | -5987.0 |
| TUBB2A | -5979.0 |
| ASB1 | -5933.0 |
| SAFB | -5899.0 |
| RNF5 | -5890.0 |
| VDAC3 | -5884.0 |
| COG8 | -5869.0 |
| CAND1 | -5838.0 |
| LYPD3 | -5828.0 |
| USP15 | -5825.0 |
| CKAP4 | -5816.0 |
| NUP210 | -5812.0 |
| NOP58 | -5810.0 |
| H2AC6 | -5775.0 |
| COMMD9 | -5746.0 |
| RBBP5 | -5722.0 |
| FEM1A | -5720.0 |
| CBX4 | -5719.0 |
| SPP2 | -5715.0 |
| FBXL5 | -5705.0 |
| WDR5 | -5702.0 |
| POMGNT2 | -5695.0 |
| H2BC15 | -5694.0 |
| ARF5 | -5690.0 |
| COMMD6 | -5687.0 |
| NPLOC4 | -5638.0 |
| RNF168 | -5628.0 |
| STAM2 | -5604.0 |
| TNIP3 | -5600.0 |
| ST8SIA4 | -5552.0 |
| WDR20 | -5534.0 |
| MIA2 | -5517.0 |
| CGA | -5492.0 |
| TPR | -5490.0 |
| FBXW10 | -5404.0 |
| RAET1G | -5385.0 |
| ASXL2 | -5366.0 |
| NEU4 | -5314.0 |
| ICMT | -5311.0 |
| NR3C1 | -5298.0 |
| H2BC6 | -5295.0 |
| C4A | -5293.5 |
| RAB11B | -5290.0 |
| KDELR2 | -5282.0 |
| HGS | -5275.0 |
| PSMC3 | -5262.0 |
| GCNT7 | -5259.0 |
| CDC73 | -5257.0 |
| TPGS2 | -5241.0 |
| TMED2 | -5231.0 |
| PMM2 | -5209.0 |
| NR5A2 | -5201.0 |
| USP3 | -5199.0 |
| PIGF | -5195.0 |
| DCUN1D1 | -5192.0 |
| RAB34 | -5174.0 |
| DYNC1I2 | -5131.0 |
| AFP | -5118.0 |
| MGAT2 | -5105.5 |
| FBXW4 | -5103.0 |
| CD55 | -5091.0 |
| MLEC | -5087.0 |
| SEC22B | -5075.0 |
| AHSG | -5072.0 |
| DNMT1 | -5071.0 |
| H2BC4 | -5066.0 |
| USP37 | -5056.0 |
| USP47 | -5054.0 |
| PSME4 | -5053.0 |
| TUBAL3 | -5043.0 |
| VWA1 | -5038.0 |
| FSTL3 | -5027.0 |
| AXIN1 | -5023.0 |
| TUBA4B | -5020.0 |
| SPTBN1 | -4995.0 |
| CUL3 | -4960.0 |
| LMAN1 | -4942.0 |
| STAMBP | -4909.0 |
| PSMA5 | -4888.0 |
| JOSD2 | -4887.0 |
| GALNT7 | -4878.0 |
| GALNT10 | -4860.0 |
| UBE2V2 | -4803.0 |
| CMAS | -4802.0 |
| NFE2L2 | -4792.0 |
| TADA3 | -4791.0 |
| NAPB | -4763.0 |
| CTBP1 | -4748.0 |
| AGBL5 | -4741.0 |
| USP14 | -4737.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| CDKN2A | -4700.0 |
| GFPT1 | -4666.0 |
| UBE2T | -4653.0 |
| ARFGAP2 | -4644.0 |
| TUBA1B | -4624.0 |
| DCAF11 | -4616.0 |
| ARSI | -4601.0 |
| ADRM1 | -4596.0 |
| B3GNT2 | -4584.0 |
| ALG14 | -4562.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| CST3 | -4543.0 |
| CHD3 | -4537.0 |
| H4C6 | -4534.0 |
| COP1 | -4515.0 |
| TGFB1 | -4499.0 |
| ACTR10 | -4445.0 |
| GFUS | -4422.0 |
| H2AC15 | -4421.0 |
| SEC24D | -4414.0 |
| PRSS23 | -4407.0 |
| TULP4 | -4395.0 |
| FBXW5 | -4387.0 |
| PPP6R3 | -4379.0 |
| NUP85 | -4358.0 |
| CNIH1 | -4356.0 |
| UBE2D1 | -4355.0 |
| MAN1B1 | -4351.0 |
| LAMB1 | -4342.0 |
| NUP98 | -4330.0 |
| ARCN1 | -4315.0 |
| COG2 | -4301.0 |
| SMC6 | -4290.0 |
| PGM3 | -4276.0 |
| PSMB6 | -4271.0 |
| DDB1 | -4266.0 |
| H2BC9 | -4255.5 |
| TBC1D20 | -4252.0 |
| ADAMTS19 | -4247.0 |
| UBE2W | -4234.0 |
| ASB3 | -4226.0 |
| PTEN | -4219.0 |
| H2AC25 | -4201.0 |
| H2BC17 | -4192.0 |
| STC2 | -4185.0 |
| INO80E | -4156.0 |
| HIC1 | -4155.0 |
| CAPZB | -4153.0 |
| RAB4A | -4137.0 |
| UBE2M | -4135.0 |
| MEPE | -4134.0 |
| B4GALT4 | -4113.0 |
| UBE2E1 | -4108.0 |
| RNF103 | -4105.0 |
| WRN | -4104.0 |
| USP49 | -4092.0 |
| USO1 | -4080.0 |
| PHC2 | -4060.0 |
| RTN4RL2 | -4058.0 |
| NCOA2 | -4049.0 |
| SNX3 | -4039.0 |
| TUBA8 | -4032.0 |
| GOSR2 | -4003.0 |
| USP48 | -3989.0 |
| DAD1 | -3986.0 |
| PSMD1 | -3979.0 |
| TRAF6 | -3967.0 |
| COPE | -3943.0 |
| OTUD3 | -3931.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| DCTN4 | -3874.0 |
| H4C4 | -3867.0 |
| ST6GAL2 | -3842.0 |
| PPP6R1 | -3834.0 |
| BMI1 | -3827.0 |
| COPS3 | -3815.0 |
| ADAMTS10 | -3813.0 |
| AMFR | -3780.0 |
| MIA3 | -3763.0 |
| MATN3 | -3753.0 |
| NSMCE2 | -3736.0 |
| RHOT1 | -3735.0 |
| TOP2B | -3669.0 |
| CHST10 | -3665.0 |
| NOD1 | -3630.0 |
| NSF | -3605.0 |
| SHPRH | -3595.0 |
| CDC34 | -3594.0 |
| H2BC26 | -3582.0 |
| KDELR3 | -3573.0 |
| UBE2Q2 | -3571.0 |
| TOP1 | -3554.0 |
| POFUT2 | -3551.0 |
| DYNLL1 | -3550.0 |
| LAMB2 | -3547.0 |
| TOPORS | -3531.0 |
| SEC24A | -3490.0 |
| FBXO41 | -3476.0 |
| ST3GAL6 | -3467.0 |
| UMOD | -3459.0 |
| TNKS | -3457.0 |
| FBXO21 | -3449.0 |
| NUP133 | -3446.0 |
| KLHL41 | -3431.0 |
| KLHL3 | -3414.0 |
| MBD6 | -3400.0 |
| GMPPB | -3391.0 |
| KLHL11 | -3387.0 |
| ABRAXAS2 | -3369.0 |
| APOE | -3335.0 |
| UAP1 | -3323.0 |
| GOLM1 | -3319.0 |
| B3GNT3 | -3317.0 |
| CREBBP | -3271.0 |
| COG3 | -3267.0 |
| NEU1 | -3266.0 |
| FBXW7 | -3233.0 |
| PIGX | -3229.0 |
| OTUD7B | -3194.0 |
| A4GNT | -3174.0 |
| SPTAN1 | -3167.0 |
| BAP1 | -3166.0 |
| CDKN1A | -3164.0 |
| ST3GAL1 | -3156.0 |
| DPH6 | -3150.0 |
| GMDS | -3136.0 |
| OBSL1 | -3116.0 |
| PSMC4 | -3089.0 |
| GOLGB1 | -3082.0 |
| RAD21 | -3080.0 |
| MUC3A | -3059.0 |
| CISH | -3049.0 |
| TMED10 | -3046.0 |
| VCP | -2987.0 |
| POLB | -2982.0 |
| SIAH2 | -2978.0 |
| ZRANB1 | -2971.0 |
| SKIC8 | -2957.0 |
| RING1 | -2953.0 |
| FUOM | -2924.0 |
| AGTPBP1 | -2920.0 |
| RAB13 | -2919.0 |
| KTN1 | -2912.0 |
| RAB43 | -2891.0 |
| DPAGT1 | -2876.0 |
| COPA | -2869.0 |
| DPM1 | -2842.0 |
| RAB40C | -2840.0 |
| TFAP2B | -2839.0 |
| NUP188 | -2837.0 |
| LARGE2 | -2816.0 |
| SUMF2 | -2809.0 |
| PSMB1 | -2799.0 |
| DMP1 | -2794.0 |
| KCTD7 | -2784.0 |
| MUC17 | -2766.0 |
| QSOX1 | -2764.0 |
| USP22 | -2756.0 |
| ASB7 | -2750.0 |
| EDEM2 | -2732.0 |
| PRKCSH | -2722.0 |
| RAB33B | -2691.0 |
| CYLD | -2673.0 |
| SPP1 | -2661.0 |
| BST1 | -2654.0 |
| RNF123 | -2635.0 |
| KAT2A | -2607.0 |
| RANGAP1 | -2606.0 |
| GCNT1 | -2595.0 |
| NUP205 | -2593.0 |
| ASB6 | -2591.0 |
| FBXL19 | -2576.0 |
| ARF3 | -2554.0 |
| NR1H2 | -2553.0 |
| SHISA5 | -2551.0 |
| TF | -2545.0 |
| F10 | -2542.0 |
| KCTD6 | -2539.0 |
| STAMBPL1 | -2534.0 |
| GALNT2 | -2528.0 |
| DPH1 | -2524.0 |
| B4GALNT2 | -2522.0 |
| MGAT5 | -2501.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| SP100 | -2471.0 |
| USP28 | -2444.0 |
| PIGU | -2443.0 |
| PCGF2 | -2415.0 |
| TAF10 | -2411.0 |
| SENP2 | -2409.0 |
| MAN1C1 | -2399.0 |
| CALM1 | -2398.0 |
| FAM20A | -2397.0 |
| INO80 | -2396.0 |
| VHL | -2369.0 |
| OTUB1 | -2364.0 |
| MUC16 | -2359.0 |
| FBXW9 | -2355.0 |
| BIRC5 | -2354.0 |
| FCSK | -2312.0 |
| UBE2D3 | -2295.0 |
| TTL | -2282.0 |
| KLHL25 | -2250.0 |
| FBXO31 | -2249.0 |
| TFG | -2248.0 |
| CDK1 | -2219.0 |
| NAE1 | -2210.0 |
| RNF181 | -2199.0 |
| DNMT3B | -2188.0 |
| TPST2 | -2186.0 |
| CUL5 | -2167.0 |
| PIGP | -2161.0 |
| B3GLCT | -2154.0 |
| PSMC6 | -2126.0 |
| BABAM1 | -2123.0 |
| ADAMTS16 | -2106.0 |
| TADA2B | -2103.0 |
| DYNC1I1 | -2088.0 |
| SPRN | -2056.0 |
| EDEM1 | -2043.0 |
| EPAS1 | -2034.0 |
| CLSPN | -2005.0 |
| WDR48 | -1996.0 |
| SCG3 | -1991.0 |
| EIF5A | -1987.0 |
| GALNT11 | -1986.0 |
| ARF4 | -1971.0 |
| CD109 | -1947.0 |
| MBD5 | -1933.0 |
| WAC | -1930.0 |
| COG7 | -1922.0 |
| TRAPPC4 | -1897.0 |
| B3GNT8 | -1871.0 |
| TTLL12 | -1865.0 |
| RCN1 | -1846.0 |
| DPH3 | -1828.0 |
| TUBA1A | -1819.0 |
| DCUN1D3 | -1814.0 |
| PML | -1804.0 |
| RAB4B | -1798.0 |
| MOGS | -1796.0 |
| KBTBD7 | -1774.0 |
| DNAJC24 | -1763.0 |
| SPON2 | -1761.0 |
| STX17 | -1737.0 |
| LMAN2L | -1731.0 |
| RAB19 | -1708.0 |
| DCAF16 | -1693.0 |
| PSMB9 | -1684.0 |
| SEC22A | -1674.0 |
| ARSB | -1666.0 |
| UBE2E3 | -1639.0 |
| MBD1 | -1631.0 |
| F2 | -1609.0 |
| CCN1 | -1595.0 |
| PIGL | -1587.0 |
| H2AC8 | -1573.0 |
| DNAJC3 | -1571.0 |
| ADAM10 | -1547.0 |
| SCMH1 | -1534.0 |
| LRRC49 | -1518.0 |
| CCP110 | -1489.0 |
| GALNT12 | -1482.0 |
| BIRC2 | -1477.0 |
| SBSPON | -1441.0 |
| USP33 | -1426.0 |
| PSMA3 | -1391.0 |
| ASB16 | -1375.0 |
| NEU3 | -1357.0 |
| COPS7B | -1343.0 |
| CNTN5 | -1342.0 |
| EEF1AKMT1 | -1204.0 |
| ADAMTS20 | -1199.0 |
| HIF3A | -1197.0 |
| SLC35A1 | -1182.0 |
| SMC5 | -1178.0 |
| RAB12 | -1167.0 |
| PUM2 | -1157.0 |
| PSME3 | -1153.0 |
| RECK | -1133.0 |
| GMPPA | -1131.0 |
| COPS7A | -1123.0 |
| GALNT17 | -1115.0 |
| SEC16A | -1111.0 |
| UCHL3 | -1106.0 |
| FBXO27 | -1090.0 |
| DOHH | -1083.0 |
| STX5 | -1070.0 |
| ART3 | -1048.0 |
| KAT2B | -1030.0 |
| H2BC8 | -1029.0 |
| ASB2 | -1013.0 |
| KLHL21 | -1009.0 |
| KLHL5 | -1006.0 |
| UBA2 | -993.0 |
| NUCB1 | -987.0 |
| DAG1 | -983.0 |
| SOCS3 | -973.0 |
| LY6G6C | -964.0 |
| LY6K | -963.0 |
| SENP5 | -948.0 |
| CDCA8 | -916.0 |
| ST3GAL4 | -910.0 |
| PLET1 | -908.0 |
| RNF2 | -892.0 |
| AURKA | -876.0 |
| FN3KRP | -866.0 |
| GALNT13 | -863.0 |
| PAF1 | -856.0 |
| RAB5C | -832.0 |
| ALG5 | -814.0 |
| MUC5B | -745.0 |
| RAB6A | -743.0 |
| FUT8 | -705.0 |
| PPARGC1A | -698.0 |
| EVA1A | -687.0 |
| PEX2 | -679.0 |
| RNF139 | -669.0 |
| RIGI | -659.0 |
| OPCML | -657.0 |
| SEL1L | -644.0 |
| PCSK9 | -608.0 |
| SLC17A5 | -584.0 |
| HNRNPK | -563.0 |
| TP53 | -548.0 |
| NUP160 | -518.0 |
| APLP2 | -511.0 |
| RAB3C | -494.0 |
| B3GNT9 | -489.0 |
| NAPA | -484.0 |
| SPTBN4 | -481.0 |
| PSMA1 | -477.0 |
| COPS2 | -471.0 |
| BET1 | -470.0 |
| MGAT4B | -468.0 |
| RNF144A | -466.0 |
| PLAUR | -387.0 |
| INO80B | -379.0 |
| COPZ1 | -343.0 |
| DCTN1 | -338.0 |
| STT3A | -325.0 |
| TRAF3 | -323.0 |
| CHST4 | -303.0 |
| ALG3 | -302.0 |
| PARP1 | -295.0 |
| RNF152 | -290.0 |
| SKP1 | -264.0 |
| PSMB8 | -260.0 |
| ANKRD9 | -243.0 |
| DDX5 | -242.0 |
| LMO7 | -241.0 |
| RAD52 | -229.0 |
| ANK1 | -220.0 |
| CP | -178.0 |
| UBA52 | -167.0 |
| UBE2B | -162.0 |
| CD59 | -154.0 |
| ARSK | -153.0 |
| STAG1 | -147.0 |
| FBXL16 | -146.0 |
| MDC1 | -145.0 |
| B4GALT6 | -111.0 |
| FBXW2 | -99.0 |
| MRTFA | -97.0 |
| GOSR1 | -79.0 |
| RRAGA | -77.0 |
| BCL10 | -56.0 |
| SATB2 | -54.0 |
| PCNA | -40.0 |
| SIN3A | -32.0 |
| MBTPS1 | -25.0 |
| ADAMTS17 | 4.0 |
| USP4 | 10.0 |
| GNPNAT1 | 23.0 |
| PROS1 | 40.0 |
| TPGS1 | 46.0 |
| FUCA1 | 90.0 |
| MDM4 | 110.0 |
| USP44 | 114.0 |
| APOA1 | 129.0 |
| DTL | 137.0 |
| RAB31 | 141.0 |
| ANK3 | 153.0 |
| ST8SIA5 | 217.0 |
| TRAPPC1 | 224.0 |
| AMBN | 240.0 |
| LYPD1 | 245.0 |
| H2AC17 | 251.0 |
| NPM1 | 252.0 |
| KDM1B | 262.0 |
| SERPINC1 | 283.0 |
| POMGNT1 | 295.0 |
| COPB1 | 335.0 |
| NUP37 | 339.0 |
| ANKRD28 | 363.0 |
| COMMD5 | 373.0 |
| ADAMTS18 | 407.0 |
| MAN1A2 | 412.0 |
| METTL21A | 431.0 |
| MCFD2 | 436.0 |
| L3MBTL2 | 443.0 |
| PSMB10 | 447.0 |
| ALG1 | 448.0 |
| MUC7 | 479.0 |
| ASGR1 | 533.0 |
| SVBP | 555.0 |
| RCE1 | 560.0 |
| THRB | 585.0 |
| ADAMTS15 | 599.0 |
| MDGA2 | 602.0 |
| MUC21 | 607.0 |
| MAP3K7 | 645.0 |
| NR2C1 | 659.0 |
| KEAP1 | 666.0 |
| GALNT15 | 693.0 |
| SMAD1 | 719.0 |
| MAVS | 726.0 |
| FBXO4 | 732.0 |
| CAPZA1 | 768.0 |
| RAB1B | 777.0 |
| PPARG | 783.0 |
| MYC | 805.0 |
| SENP8 | 850.0 |
| VCAN | 871.0 |
| TNIP1 | 876.0 |
| H4C5 | 878.0 |
| ZNF131 | 882.0 |
| USP8 | 888.0 |
| PROZ | 894.0 |
| PSMD12 | 901.0 |
| UBE2G2 | 918.0 |
| NUS1 | 922.0 |
| SEC13 | 959.0 |
| TMED9 | 966.0 |
| H2AC21 | 971.0 |
| CAPZA2 | 982.0 |
| KLHL22 | 1012.0 |
| BABAM2 | 1018.0 |
| CANX | 1053.0 |
| TUBB1 | 1069.0 |
| RAB3D | 1076.0 |
| FBXO9 | 1100.0 |
| KNG1 | 1101.0 |
| PTRH2 | 1105.0 |
| TRAF2 | 1106.0 |
| COG4 | 1128.0 |
| CHST8 | 1133.0 |
| RARA | 1135.0 |
| ACTR8 | 1139.0 |
| SMC3 | 1172.0 |
| SEMA5A | 1173.0 |
| TGFA | 1186.0 |
| DCUN1D4 | 1197.0 |
| FBXL22 | 1203.0 |
| PSMD14 | 1213.0 |
| TMED3 | 1216.0 |
| ST3GAL3 | 1227.0 |
| IZUMO1R | 1239.0 |
| GLB1 | 1247.0 |
| SUMO3 | 1249.0 |
| NSMCE3 | 1250.0 |
| DDA1 | 1269.0 |
| PHC3 | 1319.0 |
| THBS2 | 1323.0 |
| CBX5 | 1338.0 |
| RAB23 | 1344.0 |
| GP2 | 1361.0 |
| FN3K | 1366.0 |
| MAN2A1 | 1375.0 |
| ASB15 | 1379.0 |
| ARSA | 1386.0 |
| SMAD7 | 1406.0 |
| ARF1 | 1430.0 |
| LY6H | 1439.0 |
| DOLK | 1442.0 |
| FSTL1 | 1444.0 |
| TTLL7 | 1447.0 |
| HLA-A | 1455.0 |
| FBXO6 | 1457.0 |
| HIF1A | 1459.0 |
| SDC2 | 1493.0 |
| CSNK1D | 1496.0 |
| COPS8 | 1516.0 |
| ASB5 | 1572.0 |
| FBXO22 | 1618.0 |
| USP21 | 1624.0 |
| NTNG1 | 1631.0 |
| PARK7 | 1634.0 |
| RAB36 | 1635.0 |
| KLHL20 | 1651.0 |
| NUP62 | 1710.0 |
| H2AC16 | 1717.0 |
| TRAPPC6A | 1733.0 |
| PPP6C | 1738.0 |
| FAM20C | 1767.0 |
| MAT2B | 1768.0 |
| TGFBR2 | 1787.0 |
| ESR1 | 1789.0 |
| COG1 | 1790.0 |
| SEM1 | 1794.0 |
| COMMD1 | 1802.0 |
| RAB10 | 1820.0 |
| FBXW8 | 1824.0 |
| DDB2 | 1829.0 |
| WDTC1 | 1835.0 |
| RPS27A | 1846.0 |
| PIAS2 | 1863.0 |
| OS9 | 1869.0 |
| RAB27B | 1873.0 |
| ALG12 | 1880.0 |
| PIGW | 1887.0 |
| GANAB | 1897.0 |
| GALNT5 | 1914.0 |
| HIPK2 | 1915.0 |
| H2BC3 | 1920.0 |
| LTBP1 | 1954.0 |
| SPACA4 | 1956.0 |
| RAB5B | 1959.0 |
| PEX10 | 1971.0 |
| LEO1 | 1984.0 |
| EDEM3 | 1998.0 |
| RNF7 | 2019.0 |
| TEX101 | 2022.0 |
| PNPLA2 | 2033.0 |
| SSPOP | 2051.0 |
| SUMO1 | 2052.0 |
| ST8SIA6 | 2065.0 |
| NLRP3 | 2075.0 |
| ADAMTS12 | 2084.0 |
| COPS5 | 2087.0 |
| ARSJ | 2098.0 |
| PIGQ | 2110.0 |
| ST6GALNAC5 | 2120.0 |
| LRRC41 | 2122.0 |
| DPM3 | 2145.0 |
| RAB3A | 2157.0 |
| DERL1 | 2160.0 |
| SENP1 | 2164.0 |
| ALPL | 2170.0 |
| CBX2 | 2171.0 |
| FBXO7 | 2172.0 |
| ATXN3 | 2178.0 |
| PSMC5 | 2183.0 |
| SOCS2 | 2187.0 |
| RAE1 | 2192.0 |
| FEM1B | 2202.0 |
| FBXL7 | 2214.0 |
| ACTR1A | 2220.0 |
| DPH2 | 2228.0 |
| PSMD8 | 2235.0 |
| GAN | 2253.0 |
| UCHL5 | 2256.0 |
| RAB8B | 2309.0 |
| B3GNT5 | 2325.0 |
| VASH2 | 2336.0 |
| B4GALT3 | 2344.0 |
| NANP | 2350.0 |
| SUMF1 | 2361.0 |
| TNC | 2387.0 |
| IGFBP7 | 2406.0 |
| PIAS3 | 2421.0 |
| C3 | 2422.0 |
| UBXN7 | 2443.0 |
| TTLL4 | 2449.0 |
| SEC23IP | 2511.0 |
| TMED7 | 2537.0 |
| LRR1 | 2559.0 |
| PDIA3 | 2577.0 |
| ST8SIA3 | 2624.0 |
| KLHL2 | 2629.0 |
| GALNT9 | 2631.0 |
| COPZ2 | 2659.0 |
| TRIM25 | 2692.0 |
| MTA1 | 2697.0 |
| DCUN1D5 | 2713.0 |
| ANK2 | 2744.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| RORA | 2763.0 |
| USP34 | 2769.0 |
| USP16 | 2770.0 |
| AGBL3 | 2783.0 |
| GFPT2 | 2784.0 |
| SPSB4 | 2801.0 |
| DCAF6 | 2849.0 |
| NDC1 | 2860.0 |
| GPIHBP1 | 2894.0 |
| MAN1A1 | 2898.0 |
| CPM | 2907.0 |
| ING2 | 2929.0 |
| FBN1 | 2972.0 |
| HDAC7 | 2984.0 |
| PRKN | 2992.0 |
| AGBL2 | 3006.0 |
| RANBP2 | 3016.0 |
| ADAMTS9 | 3029.0 |
| RAD23B | 3038.0 |
| ARRB1 | 3054.0 |
| RNF146 | 3055.0 |
| ARFGAP3 | 3056.0 |
| RAB8A | 3057.0 |
| DCAF8 | 3098.0 |
| TP53BP1 | 3107.0 |
| PIGN | 3109.0 |
| SMAD4 | 3126.0 |
| USP2 | 3157.0 |
| THSD7A | 3183.0 |
| DPH7 | 3205.0 |
| TUBA3C | 3214.0 |
| B3GALNT2 | 3228.0 |
| UGGT2 | 3261.0 |
| INO80C | 3272.0 |
| USP5 | 3273.0 |
| RELA | 3308.0 |
| DCAF10 | 3343.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| MUCL1 | 3409.0 |
| IGFBP4 | 3411.0 |
| NRIP1 | 3416.0 |
| MELTF | 3424.0 |
| EEF1A1 | 3449.0 |
| UIMC1 | 3452.0 |
| PROC | 3455.0 |
| GPS1 | 3470.0 |
| VNN1 | 3488.0 |
| PIGB | 3516.0 |
| GALNT1 | 3535.0 |
| TUBB6 | 3539.0 |
| GALNTL6 | 3566.0 |
| ETFBKMT | 3591.0 |
| FBXO32 | 3601.0 |
| RAB44 | 3610.0 |
| TUBB4A | 3612.0 |
| TOMM70 | 3613.0 |
| GALNT16 | 3637.0 |
| PEX5 | 3643.0 |
| FBXL18 | 3661.0 |
| PIAS4 | 3685.0 |
| H2AC11 | 3693.0 |
| THRA | 3700.0 |
| RXRA | 3719.0 |
| KLHL9 | 3736.0 |
| TTLL3 | 3751.0 |
| VDAC1 | 3778.0 |
| TECTB | 3785.0 |
| ST3GAL2 | 3796.0 |
| ALB | 3805.0 |
| RAB29 | 3811.0 |
| RNF185 | 3832.0 |
| SQSTM1 | 3845.0 |
| SP3 | 3857.0 |
| YOD1 | 3858.0 |
| NTM | 3875.0 |
| PIAS1 | 3878.0 |
| BLM | 3894.0 |
| ARFGAP1 | 3928.0 |
| SCFD1 | 3937.0 |
| PTP4A2 | 3951.0 |
| LAMC1 | 3961.0 |
| RAB3B | 4002.0 |
| NANS | 4006.0 |
| NUP153 | 4025.0 |
| RAB27A | 4059.0 |
| NEDD8 | 4083.0 |
| CAMKMT | 4120.0 |
| NTNG2 | 4124.0 |
| RAB21 | 4128.0 |
| SOCS6 | 4142.0 |
| NEURL2 | 4146.0 |
| F7 | 4152.0 |
| EIF5A2 | 4165.0 |
| NUP54 | 4170.0 |
| ERCC8 | 4217.0 |
| FBXL8 | 4221.0 |
| MGAT4C | 4233.0 |
| RAB20 | 4249.0 |
| AAAS | 4254.0 |
| TRIM4 | 4255.0 |
| NR1H3 | 4271.0 |
| TRIM28 | 4273.0 |
| ADRB2 | 4307.0 |
| MUC4 | 4336.0 |
| IFIH1 | 4344.0 |
| RAB5A | 4358.0 |
| CCNA2 | 4366.0 |
| SUDS3 | 4380.0 |
| CUL1 | 4399.0 |
| FBXO15 | 4405.0 |
| MVD | 4411.0 |
| RAB25 | 4455.0 |
| RAB35 | 4484.0 |
| VGF | 4495.0 |
| DERL2 | 4498.0 |
| COPB2 | 4499.0 |
| GALNT14 | 4501.0 |
| HSP90B1 | 4519.0 |
| ENAM | 4534.0 |
| ELOC | 4538.0 |
| ADAMTS6 | 4546.0 |
| GALNT18 | 4568.0 |
| LYPD5 | 4573.0 |
| DCAF13 | 4623.0 |
| CTSZ | 4658.0 |
| OTOA | 4667.0 |
| RAB1A | 4669.0 |
| FEM1C | 4684.0 |
| LYPD4 | 4687.0 |
| SPON1 | 4705.0 |
| ZBTB16 | 4731.0 |
| VDAC2 | 4743.0 |
| PIGY | 4744.0 |
| RAB30 | 4747.0 |
| SKP2 | 4760.0 |
| RPS2 | 4762.0 |
| CALR | 4769.0 |
| DPP3 | 4774.0 |
| UHRF2 | 4793.0 |
| BTBD1 | 4794.0 |
| PDIA6 | 4836.0 |
| GALNT6 | 4865.0 |
| AURKB | 4877.0 |
| IGFBP5 | 4893.0 |
| UBE2N | 4905.0 |
| COPG1 | 4917.0 |
| NOTUM | 4941.0 |
| UBXN1 | 4957.0 |
| MANEA | 4964.0 |
| PSMB4 | 4971.0 |
| DCTN6 | 4994.0 |
| GALNT3 | 5005.0 |
| UBE2J2 | 5012.0 |
| H4C3 | 5053.0 |
| NPL | 5078.0 |
| TFPT | 5101.0 |
| B4GALT5 | 5147.0 |
| ACTB | 5155.0 |
| NAGK | 5205.0 |
| THSD4 | 5218.0 |
| PSMF1 | 5221.0 |
| ST6GALNAC3 | 5225.0 |
| DOLPP1 | 5264.0 |
| TOMM20 | 5271.0 |
| NFKB2 | 5274.0 |
| PSMD7 | 5305.0 |
| NSMCE1 | 5318.0 |
| SEC16B | 5347.0 |
| TTLL13 | 5353.0 |
| AGBL4 | 5357.0 |
| NUP58 | 5365.0 |
| TNFAIP3 | 5373.0 |
| RNF135 | 5408.0 |
| MITF | 5434.0 |
| KBTBD8 | 5462.0 |
| GALNT4 | 5463.0 |
| UBE2S | 5479.0 |
| TTLL8 | 5506.0 |
| PMM1 | 5511.0 |
| DCAF17 | 5520.0 |
| ST6GALNAC6 | 5523.0 |
| MPDU1 | 5549.0 |
| DAXX | 5566.0 |
| FBXO30 | 5597.0 |
| YKT6 | 5640.0 |
| SEH1L | 5647.0 |
| ARSG | 5662.0 |
| USP7 | 5667.0 |
| ASB18 | 5668.0 |
| DPM2 | 5703.0 |
| COMMD4 | 5736.0 |
| MDM2 | 5757.0 |
| CFTR | 5784.0 |
| IDE | 5797.0 |
| PSMB2 | 5803.0 |
| SPSB2 | 5811.0 |
| PEX13 | 5822.0 |
| FBXL20 | 5823.0 |
| FBXW11 | 5855.0 |
| PSMB7 | 5858.0 |
| H2AC1 | 5861.0 |
| PIGC | 5891.0 |
| RAB26 | 5915.0 |
| GCNT3 | 5936.0 |
| PRMT3 | 5952.0 |
| RTF1 | 5978.0 |
| POMT2 | 6005.0 |
| TRAPPC5 | 6037.0 |
| FPGT | 6076.0 |
| NEGR1 | 6107.0 |
| INO80D | 6156.0 |
| ADAMTS13 | 6177.0 |
| RAB39A | 6205.0 |
| TUBB3 | 6221.0 |
| USP18 | 6237.0 |
| DCTN2 | 6256.0 |
| HNRNPC | 6281.0 |
| LSAMP | 6328.0 |
| UBE2K | 6333.0 |
| FKBP8 | 6364.0 |
| RFT1 | 6366.0 |
| NUB1 | 6372.0 |
| ASGR2 | 6395.0 |
| CTSC | 6412.0 |
| PSCA | 6427.0 |
| MUC6 | 6444.0 |
| H2BC11 | 6454.0 |
| TGOLN2 | 6481.0 |
| ADAMTS4 | 6491.0 |
| PSMA8 | 6502.0 |
| TECTA | 6526.0 |
| FBXL15 | 6537.0 |
| PRND | 6551.0 |
| FOLR1 | 6558.0 |
| UBE2D2 | 6564.0 |
| RAB6B | 6569.0 |
| AMDHD2 | 6584.0 |
| MUC1 | 6591.0 |
| PSMD6 | 6616.0 |
| ADAMTSL3 | 6620.0 |
| RAB42 | 6625.0 |
| JOSD1 | 6631.0 |
| PSME2 | 6638.0 |
| KDELR1 | 6652.0 |
| RNF40 | 6660.0 |
| H2AC12 | 6666.0 |
| NR5A1 | 6673.0 |
| RABGGTB | 6678.0 |
| UBC | 6700.0 |
| ALG2 | 6746.0 |
| PIGZ | 6767.0 |
| MSLN | 6769.0 |
| B4GALT2 | 6778.0 |
| OTUB2 | 6781.0 |
| ST6GAL1 | 6794.0 |
| UBE2L3 | 6820.0 |
| DYNC1LI1 | 6830.0 |
| IKBKE | 6845.0 |
| SPTBN2 | 6888.0 |
| TPST1 | 6892.0 |
| PREB | 6900.0 |
| H2AC4 | 6905.0 |
| MPI | 6913.0 |
| ALG10 | 6915.0 |
| TTLL9 | 6921.0 |
| ASXL1 | 6941.0 |
| PSMA6 | 6984.0 |
| RAB37 | 7029.0 |
| VNN2 | 7054.0 |
| FBXL13 | 7055.0 |
| FBXL3 | 7071.0 |
| FOXK2 | 7105.0 |
| MUC5AC | 7128.0 |
| SLC35C1 | 7138.0 |
| ADAMTSL5 | 7169.0 |
| UBE2I | 7189.0 |
| CDC20 | 7234.0 |
| FURIN | 7240.0 |
| FBXL4 | 7276.0 |
| TNIP2 | 7285.0 |
| LARGE1 | 7290.0 |
| RWDD3 | 7296.0 |
| FBXL12 | 7309.0 |
| CNTN4 | 7315.0 |
| VDR | 7351.0 |
| THSD1 | 7356.0 |
| H2BC21 | 7408.0 |
| UBA3 | 7409.0 |
| NUP155 | 7411.0 |
| PEX12 | 7440.0 |
| DCTN5 | 7453.0 |
| ADAMTSL1 | 7471.0 |
| NOD2 | 7481.0 |
| ST3GAL5 | 7488.0 |
| TMEM132A | 7491.0 |
| NR1H4 | 7526.0 |
| PSMA4 | 7568.0 |
| CSF1 | 7581.0 |
| UBB | 7594.0 |
| LMAN1L | 7626.0 |
| TMEM129 | 7641.0 |
| AGBL1 | 7642.0 |
| ADAMTS3 | 7651.0 |
| VCPIP1 | 7652.0 |
| SPSB1 | 7670.0 |
| H2BC12 | 7676.0 |
| FN1 | 7701.0 |
| THY1 | 7717.0 |
| ASB4 | 7736.0 |
| HSPA8 | 7737.0 |
| WSB1 | 7749.0 |
| B4GALT1 | 7755.0 |
| COPS4 | 7773.0 |
| CCDC8 | 7810.0 |
| GALNT8 | 7818.0 |
| CTSA | 7830.0 |
| RHOA | 7838.0 |
| LY6D | 7865.0 |
| SMAD3 | 7915.0 |
| P4HB | 7917.0 |
| ITIH2 | 7950.0 |
| EID3 | 7968.0 |
| RAB24 | 7998.0 |
| TRAPPC3 | 8004.0 |
| ST8SIA1 | 8011.0 |
| PSMB3 | 8017.0 |
| SEC22C | 8078.0 |
| CEACAM5 | 8091.0 |
| WFS1 | 8124.0 |
| CNIH2 | 8159.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| B3GNT7 | 8239.0 |
| BET1L | 8253.0 |
| SMURF2 | 8269.0 |
| ADAMTS2 | 8275.0 |
| PIGV | 8301.0 |
| SEMA5B | 8343.0 |
| ART4 | 8352.0 |
| SAR1B | 8361.0 |
| OTUD7A | 8369.0 |
| GPAA1 | 8378.0 |
| FOLR2 | 8385.0 |
| PGAP1 | 8423.0 |
| MUC15 | 8510.0 |
| CALU | 8520.0 |
| ADAMTSL4 | 8529.0 |
| PIGO | 8538.0 |
| ST6GALNAC2 | 8585.0 |
| RAB17 | 8677.0 |
| ADAMTS8 | 8708.0 |
| NSMCE4A | 8710.0 |
| H2AC20 | 8750.0 |
| COPS6 | 8762.0 |
| TTLL10 | 8774.0 |
| H4C1 | 8782.0 |
| SPTB | 8798.0 |
| TTLL1 | 8834.0 |
| FGF23 | 8849.0 |
| ADAMTSL2 | 8855.0 |
| SCG2 | 8981.0 |
| ST8SIA2 | 8982.0 |
| CD52 | 9007.0 |
| RPN1 | 9028.0 |
| SYVN1 | 9031.0 |
| OTULIN | 9125.0 |
| PIGT | 9153.0 |
| APOA5 | 9156.0 |
| USP12 | 9184.0 |
| RTN4RL1 | 9196.0 |
| ST6GALNAC4 | 9222.0 |
| RAD23A | 9233.0 |
| GRIA1 | 9243.0 |
| B3GNT4 | 9249.0 |
| GALNTL5 | 9258.0 |
| TTLL6 | 9289.0 |
| H2AC14 | 9376.0 |
| SPTBN5 | 9388.0 |
| UBE2Z | 9396.0 |
| COL7A1 | 9425.0 |
| TTLL11 | 9454.0 |
| THSD7B | 9457.0 |
| ANO8 | 9487.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| FBXO17 | 9565.0 |
| FBXL14 | 9573.0 |
| PRSS21 | 9577.0 |
| COMMD8 | 9643.0 |
| B3GNT6 | 9671.0 |
| FBXW12 | 9679.0 |
| SPARCL1 | 9684.0 |
| FGG | 9690.0 |
| SERPINA1 | 9692.0 |
| PSME1 | 9765.0 |
| ADAMTS14 | 9780.0 |
| CNTN3 | 9797.0 |
| SERPINA10 | 9840.0 |
| USP25 | 9841.0 |
| LY6E | 9843.0 |
| MXRA8 | 9932.0 |
| FBXO44 | 9941.0 |
| LYPD6B | 9956.0 |
| FBXO2 | 9977.0 |
| TRAPPC2L | 10024.0 |
| H4C12 | 10027.0 |
| IL33 | 10100.0 |
| H2BC14 | 10168.0 |
| EEF2 | 10179.0 |
| COMMD7 | 10268.0 |
| RBX1 | 10301.0 |
| BGLAP | 10313.0 |
| ALPI | 10358.0 |
| HRC | 10399.0 |
| BPIFB2 | 10403.0 |
| ASB10 | 10412.0 |
| LYPD2 | 10441.0 |
| NICN1 | 10490.0 |
| FBXO40 | 10500.0 |
| ST6GALNAC1 | 10507.0 |
| ASB17 | 10512.0 |
| ELOB | 10514.0 |
| MGAT3 | 10665.0 |
| AREG | 10726.0 |
| CHML | 10768.0 |
| LGALS1 | 10825.0 |
| MUC20 | 10888.0 |
| MUC13 | 10921.0 |
| FGA | 10990.0 |
| CAPZA3 | 10997.0 |
| INS | 11042.0 |
| FUT3 | 11068.0 |
| B4GAT1 | 11289.0 |
| TUBB8 | 11325.0 |
| CEACAM7 | 11358.0 |
| LYPD8 | 11545.0 |
REACTOME_MRNA_SPLICING
| 1143 | |
|---|---|
| set | REACTOME_MRNA_SPLICING |
| setSize | 197 |
| pANOVA | 4.45e-05 |
| s.dist | -0.169 |
| p.adjustANOVA | 0.00465 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| EIF4A3 | -9788 |
| DDX39B | -9566 |
| DHX16 | -9334 |
| SNRNP200 | -9279 |
| TCERG1 | -9231 |
| GPATCH1 | -9155 |
| AQR | -9124 |
| SMU1 | -9068 |
| PPIE | -8917 |
| SNU13 | -8840 |
| NSRP1 | -8755 |
| BUD31 | -8705 |
| HNRNPH1 | -8685 |
| DHX38 | -8620 |
| CHERP | -8573 |
| YJU2 | -8567 |
| WDR70 | -8530 |
| CWC22 | -8401 |
| SNRNP70 | -8255 |
| SLU7 | -8211 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| EIF4A3 | -9788 |
| DDX39B | -9566 |
| DHX16 | -9334 |
| SNRNP200 | -9279 |
| TCERG1 | -9231 |
| GPATCH1 | -9155 |
| AQR | -9124 |
| SMU1 | -9068 |
| PPIE | -8917 |
| SNU13 | -8840 |
| NSRP1 | -8755 |
| BUD31 | -8705 |
| HNRNPH1 | -8685 |
| DHX38 | -8620 |
| CHERP | -8573 |
| YJU2 | -8567 |
| WDR70 | -8530 |
| CWC22 | -8401 |
| SNRNP70 | -8255 |
| SLU7 | -8211 |
| SNRNP48 | -8100 |
| RBM8A | -7974 |
| RBM5 | -7948 |
| PPP1R8 | -7943 |
| SF3B5 | -7928 |
| RNPC3 | -7642 |
| SRSF9 | -7628 |
| SF3A3 | -7579 |
| POLR2A | -7443 |
| PRPF3 | -7409 |
| SNIP1 | -7405 |
| LUC7L3 | -7296 |
| SNRPB | -7144 |
| BUD13 | -7079 |
| PPIL3 | -6952 |
| U2SURP | -6931 |
| CWF19L2 | -6798 |
| NCBP1 | -6659 |
| SRSF2 | -6648 |
| SNRPD2 | -6623 |
| ZMAT5 | -6486 |
| SUGP1 | -6448 |
| TFIP11 | -6393 |
| POLR2K | -6386 |
| LSM2 | -6210 |
| SRRM1 | -6188 |
| RNPS1 | -5988 |
| SNRNP40 | -5897 |
| BCAS2 | -5871 |
| PRPF18 | -5822 |
| ALYREF | -5793 |
| CCAR1 | -5744 |
| PNN | -5581 |
| RBM22 | -5571 |
| PRCC | -5481 |
| SF3B4 | -5403 |
| CTNNBL1 | -5340 |
| PRPF38A | -5034 |
| LSM3 | -4982 |
| LSM8 | -4946 |
| RBM17 | -4872 |
| CRNKL1 | -4726 |
| SF3A2 | -4651 |
| POLR2J | -4576 |
| PPIL1 | -4564 |
| ACIN1 | -4440 |
| PRPF19 | -4349 |
| DNAJC8 | -4175 |
| FUS | -4173 |
| ISY1 | -4170 |
| POLR2B | -4142 |
| LSM4 | -3953 |
| SRSF12 | -3860 |
| SRRM2 | -3777 |
| SRSF5 | -3776 |
| PUF60 | -3724 |
| DHX9 | -3722 |
| LSM5 | -3706 |
| DDX23 | -3700 |
| SRSF6 | -3471 |
| GTF2F1 | -3422 |
| RBM42 | -3380 |
| UBL5 | -3297 |
| SRSF8 | -3290 |
| YBX1 | -3218 |
| SNRPN | -3030 |
| DDX46 | -2992 |
| HNRNPR | -2852 |
| HNRNPA1 | -2749 |
| RBM25 | -2456 |
| SNRNP27 | -2216 |
| SART1 | -2165 |
| DHX8 | -1818 |
| PPIL2 | -1788 |
| SNRPD1 | -1764 |
| HNRNPM | -1739 |
| PHF5A | -1705 |
| HNRNPA2B1 | -1681 |
| SNW1 | -1658 |
| GTF2F2 | -1647 |
| EFTUD2 | -1614 |
| POLR2H | -1463 |
| TXNL4A | -1415 |
| PDCD7 | -1150 |
| HNRNPA3 | -1141 |
| PLRG1 | -1130 |
| SF3A1 | -1025 |
| DHX15 | -922 |
| CWC27 | -851 |
| HNRNPD | -848 |
| HNRNPL | -818 |
| U2AF1L4 | -586 |
| HNRNPK | -563 |
| WBP4 | -547 |
| POLR2C | -541 |
| SYF2 | -376 |
| DDX5 | -242 |
| POLR2L | -110 |
| IK | -90 |
| LENG1 | -82 |
| PPIL4 | -37 |
| DDX42 | 107 |
| FAM32A | 216 |
| PRPF40A | 263 |
| DHX35 | 367 |
| SRSF1 | 738 |
| PRPF6 | 800 |
| SDE2 | 988 |
| PRPF8 | 1029 |
| SF1 | 1242 |
| PPIG | 1280 |
| CASC3 | 1346 |
| RBM7 | 1448 |
| SAP18 | 1462 |
| ZNF830 | 1501 |
| MFAP1 | 1567 |
| U2AF2 | 1614 |
| POLR2E | 1649 |
| GCFC2 | 1864 |
| C9orf78 | 1951 |
| SNRPE | 1962 |
| SF3B1 | 1990 |
| NCBP2 | 2018 |
| SF3B3 | 2027 |
| PCBP1 | 2046 |
| PTBP1 | 2102 |
| MAGOHB | 2146 |
| PRPF31 | 2182 |
| SNRPG | 2687 |
| SRSF4 | 2689 |
| MTREX | 2694 |
| SRSF3 | 2727 |
| SMNDC1 | 2776 |
| CACTIN | 2780 |
| SRRT | 3040 |
| MAGOH | 3080 |
| SRSF11 | 3315 |
| SNRPD3 | 3490 |
| HNRNPU | 3503 |
| ZCRB1 | 3571 |
| SNRPC | 3727 |
| PRPF4 | 3784 |
| XAB2 | 4144 |
| PRKRIP1 | 4474 |
| PPIH | 4543 |
| POLR2I | 4862 |
| HNRNPF | 5109 |
| LSM7 | 5231 |
| CDC40 | 5642 |
| PPWD1 | 5750 |
| SNRPA | 5751 |
| SF3B2 | 6090 |
| USP39 | 6140 |
| HNRNPC | 6281 |
| LSM6 | 6490 |
| CDC5L | 6901 |
| SNRNP35 | 6907 |
| RBM39 | 6995 |
| SNRPA1 | 7675 |
| SRSF7 | 7689 |
| DDX41 | 7721 |
| CWC15 | 7725 |
| HSPA8 | 7737 |
| ZMAT2 | 7856 |
| SNRNP25 | 7876 |
| TRA2B | 7992 |
| CWC25 | 8038 |
| CCDC12 | 8169 |
| SNRPB2 | 8291 |
| POLR2D | 8323 |
| SNRPF | 8331 |
| POLR2F | 8864 |
| SRSF10 | 8934 |
| WBP11 | 8945 |
| POLR2G | 9208 |
| PCBP2 | 9546 |
| SF3B6 | 10032 |
REACTOME_MITOTIC_G2_G2_M_PHASES
| 816 | |
|---|---|
| set | REACTOME_MITOTIC_G2_G2_M_PHASES |
| setSize | 194 |
| pANOVA | 4.53e-05 |
| s.dist | -0.17 |
| p.adjustANOVA | 0.00465 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CDK11A | -9721 |
| FOXM1 | -9614 |
| PPP2R1B | -9252 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| PSMD2 | -8887 |
| TUBA1C | -8675 |
| LIN9 | -8611 |
| PSMB11 | -8512 |
| TUBG2 | -8420 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| PSMC1 | -7848 |
| BORA | -7784 |
| CEP164 | -7722 |
| CDK11B | -7666 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CDK11A | -9721 |
| FOXM1 | -9614 |
| PPP2R1B | -9252 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| PSMD2 | -8887 |
| TUBA1C | -8675 |
| LIN9 | -8611 |
| PSMB11 | -8512 |
| TUBG2 | -8420 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| PSMC1 | -7848 |
| BORA | -7784 |
| CEP164 | -7722 |
| CDK11B | -7666 |
| CKAP5 | -7526 |
| PSMD13 | -7362 |
| BTRC | -7343 |
| EP300 | -7126 |
| ODF2 | -7061 |
| CCNB2 | -6945 |
| LCMT1 | -6864 |
| CDC25A | -6647 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| PSMD3 | -6608 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| PSMD9 | -6463 |
| CEP152 | -6444 |
| PSMD4 | -6409 |
| CEP131 | -6383 |
| PSMB5 | -6339 |
| TUBB2B | -6314 |
| LIN54 | -6191 |
| CEP72 | -6174 |
| CENPF | -6110 |
| PSMD11 | -6044 |
| PSMC2 | -6032 |
| HAUS5 | -6025 |
| TUBB2A | -5979 |
| TUBGCP5 | -5800 |
| TUBGCP6 | -5669 |
| CLASP1 | -5346 |
| PSMC3 | -5262 |
| PPP1R12A | -5243 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| PSME4 | -5053 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CEP43 | -4973 |
| AJUBA | -4908 |
| PSMA5 | -4888 |
| SDCCAG8 | -4735 |
| PSMD5 | -4711 |
| TUBA1B | -4624 |
| PCNT | -4617 |
| CDC25C | -4507 |
| CEP250 | -4503 |
| CDK7 | -4467 |
| XPO1 | -4345 |
| PPP2R2A | -4274 |
| PSMB6 | -4271 |
| GTSE1 | -4241 |
| CEP41 | -4178 |
| HSP90AB1 | -4117 |
| MYBL2 | -4072 |
| TUBA8 | -4032 |
| PSMD1 | -3979 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| CDC25B | -3439 |
| AKAP9 | -3238 |
| CDKN1A | -3164 |
| PSMC4 | -3089 |
| PSMB1 | -2799 |
| CEP70 | -2717 |
| PAFAH1B1 | -2571 |
| E2F3 | -2555 |
| CCNA1 | -2494 |
| PSMA2 | -2485 |
| CCNH | -2298 |
| CDK1 | -2219 |
| PSMC6 | -2126 |
| HAUS6 | -2029 |
| CEP290 | -2002 |
| MNAT1 | -1983 |
| TUBGCP3 | -1900 |
| TUBA1A | -1819 |
| PPP1CB | -1732 |
| PSMB9 | -1684 |
| CDK5RAP2 | -1570 |
| CCP110 | -1489 |
| PSMA3 | -1391 |
| TPX2 | -1344 |
| PSME3 | -1153 |
| FKBPL | -1084 |
| AURKA | -876 |
| TP53 | -548 |
| YWHAE | -521 |
| PSMA1 | -477 |
| HMMR | -476 |
| LIN37 | -421 |
| DCTN1 | -338 |
| WEE1 | -335 |
| TUBGCP2 | -268 |
| SKP1 | -264 |
| PSMB8 | -260 |
| NEK2 | -182 |
| UBA52 | -167 |
| CEP78 | 13 |
| YWHAG | 115 |
| LIN52 | 259 |
| TUBB | 261 |
| PSMB10 | 447 |
| OPTN | 580 |
| NEDD1 | 779 |
| PSMD12 | 901 |
| HAUS3 | 961 |
| NME7 | 1011 |
| CENPJ | 1016 |
| TUBB1 | 1069 |
| PSMD14 | 1213 |
| CSNK1E | 1281 |
| PPME1 | 1452 |
| CSNK1D | 1496 |
| SEM1 | 1794 |
| PHLDA1 | 1804 |
| RPS27A | 1846 |
| SSNA1 | 2103 |
| PSMC5 | 2183 |
| FBXL7 | 2214 |
| ACTR1A | 2220 |
| PSMD8 | 2235 |
| SFI1 | 2352 |
| MAPRE1 | 2575 |
| ALMS1 | 2804 |
| E2F1 | 2922 |
| RAB8A | 3057 |
| TUBA3C | 3214 |
| PPP2CB | 3417 |
| TUBB6 | 3539 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| TUBB4A | 3612 |
| FBXL18 | 3661 |
| PPP1R12B | 3710 |
| PRKAR2B | 4071 |
| CCNA2 | 4366 |
| RBBP4 | 4375 |
| CUL1 | 4399 |
| HSP90AA1 | 4414 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| PKMYT1 | 4486 |
| HAUS2 | 4581 |
| HAUS4 | 4825 |
| PSMB4 | 4971 |
| CDK2 | 5165 |
| PSMF1 | 5221 |
| PSMD7 | 5305 |
| HAUS1 | 5311 |
| PSMB2 | 5803 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| FBXW11 | 5855 |
| PSMB7 | 5858 |
| PRKACA | 6168 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| PSMA8 | 6502 |
| PSMD6 | 6616 |
| PSME2 | 6638 |
| MZT2B | 6651 |
| UBC | 6700 |
| PSMA6 | 6984 |
| PSMA4 | 7568 |
| UBB | 7594 |
| PSMB3 | 8017 |
| PSMA7 | 9563 |
| NINL | 9656 |
| PSME1 | 9765 |
| RBX1 | 10301 |
| TUBB8 | 11325 |
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT
| 729 | |
|---|---|
| set | REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT |
| setSize | 236 |
| pANOVA | 5.99e-05 |
| s.dist | 0.152 |
| p.adjustANOVA | 0.00578 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| SLC35B2 | 11311 |
| SLC34A1 | 11198 |
| FGF21 | 11156 |
| SLC2A7 | 11144 |
| LCN9 | 10977 |
| SLC22A11 | 10910 |
| SLC7A7 | 10890 |
| SLC5A12 | 10779 |
| SLC7A9 | 10727 |
| SLC6A7 | 10701 |
| LCN12 | 10601 |
| SLC39A4 | 10572 |
| SLCO1C1 | 10539 |
| SLC16A3 | 10351 |
| SLC13A1 | 10198 |
| BSG | 10115 |
| SLCO2B1 | 10058 |
| SLC45A3 | 10006 |
| SLC38A3 | 9973 |
| SLC34A3 | 9961 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| SLC35B2 | 11311 |
| SLC34A1 | 11198 |
| FGF21 | 11156 |
| SLC2A7 | 11144 |
| LCN9 | 10977 |
| SLC22A11 | 10910 |
| SLC7A7 | 10890 |
| SLC5A12 | 10779 |
| SLC7A9 | 10727 |
| SLC6A7 | 10701 |
| LCN12 | 10601 |
| SLC39A4 | 10572 |
| SLCO1C1 | 10539 |
| SLC16A3 | 10351 |
| SLC13A1 | 10198 |
| BSG | 10115 |
| SLCO2B1 | 10058 |
| SLC45A3 | 10006 |
| SLC38A3 | 9973 |
| SLC34A3 | 9961 |
| SLC13A5 | 9909 |
| SLCO1A2 | 9908 |
| SLC4A9 | 9733 |
| SLC5A4 | 9554 |
| SLC30A2 | 9525 |
| SLC18A1 | 9432 |
| SLC5A1 | 9427 |
| SLC26A3 | 9401 |
| SLC6A12 | 9380 |
| SLC43A2 | 9371 |
| SLC14A2 | 9283 |
| SLC26A7 | 9262 |
| SLC34A2 | 9194 |
| LCN15 | 9178 |
| SLC44A4 | 9128 |
| SLC22A4 | 9097 |
| SLC22A6 | 8942 |
| SLC12A3 | 8909 |
| SLC30A3 | 8737 |
| SLCO4A1 | 8680 |
| SLC15A4 | 8416 |
| SLC5A11 | 8359 |
| SLC13A2 | 8232 |
| SLC27A4 | 8132 |
| SLC11A1 | 8130 |
| SLC4A4 | 8049 |
| SLCO4C1 | 8026 |
| SLC24A3 | 8014 |
| SLC28A1 | 7962 |
| SLC26A4 | 7952 |
| SLC2A1 | 7922 |
| MFSD4B | 7811 |
| SLC4A10 | 7794 |
| SLC31A1 | 7780 |
| SLC26A9 | 7666 |
| SLC25A18 | 7639 |
| SLC22A7 | 7589 |
| SLC2A4 | 7564 |
| SLC30A8 | 7469 |
| SLC39A3 | 7459 |
| SLC44A1 | 7413 |
| SLC5A7 | 7406 |
| SLC22A16 | 7384 |
| SLC25A22 | 7177 |
| SLC35C1 | 7138 |
| SLC24A1 | 6937 |
| SLC44A5 | 6803 |
| SLC1A5 | 6642 |
| SLC1A6 | 6386 |
| SLC50A1 | 6124 |
| SLC4A5 | 6121 |
| SLC22A8 | 6079 |
| SLC15A1 | 5880 |
| SLC5A2 | 5752 |
| SLC5A10 | 5648 |
| SLC8B1 | 5579 |
| SLC47A1 | 5517 |
| SLC2A13 | 5513 |
| SLC7A6 | 5467 |
| SLC17A1 | 5453 |
| SLC1A2 | 5390 |
| SLC39A14 | 5333 |
| RHBG | 5244 |
| SLC22A3 | 5185 |
| SLCO1B1 | 4937 |
| SLC1A1 | 4850 |
| SLC4A1 | 4842 |
| ARL2 | 4840 |
| SLC24A2 | 4772 |
| SLC9A9 | 4646 |
| SLC9A1 | 4618 |
| SLC7A10 | 4523 |
| SLC5A9 | 4476 |
| SLC26A1 | 4462 |
| SLC7A8 | 4413 |
| SLC24A4 | 4393 |
| SLC39A10 | 4363 |
| SLC25A29 | 4176 |
| SLC10A6 | 3709 |
| SLC39A2 | 3659 |
| SLC39A8 | 3649 |
| AVP | 3646 |
| SLC8A1 | 3640 |
| SLCO2A1 | 3550 |
| SLC12A1 | 3519 |
| SLC6A1 | 3471 |
| SLC9A4 | 3468 |
| ARL2BP | 3430 |
| SLC6A13 | 3391 |
| APOD | 3339 |
| SLC8A3 | 3327 |
| SLC2A12 | 3325 |
| SLC22A2 | 3319 |
| SLC1A7 | 3235 |
| AHCYL2 | 3189 |
| SLC29A3 | 3032 |
| SLC4A2 | 2775 |
| SLC6A6 | 2756 |
| SLC17A6 | 2476 |
| SLC35D2 | 2418 |
| SLC5A8 | 2334 |
| SLC27A1 | 2104 |
| SLC44A2 | 2080 |
| SLC29A2 | 1932 |
| SLC5A6 | 1830 |
| SLC35A3 | 1815 |
| SLC6A2 | 1742 |
| CTNS | 1704 |
| SLC15A3 | 1702 |
| SLC17A8 | 1673 |
| SLC44A3 | 1642 |
| SLCO3A1 | 1505 |
| SLC13A3 | 1491 |
| SLC41A1 | 1461 |
| SLC36A4 | 1345 |
| SLC35B3 | 1194 |
| SLCO1B3 | 1148 |
| SLC5A3 | 1061 |
| SLC22A12 | 921 |
| EMB | 914 |
| SLC47A2 | 865 |
| SLC1A3 | 708 |
| SLC35D1 | 587 |
| SLC9A3 | 540 |
| SLC3A2 | 490 |
| SLC38A4 | 351 |
| SLC6A11 | 296 |
| SLC9A2 | 214 |
| SLC5A5 | 127 |
| SLC8A2 | 122 |
| SLC39A1 | 99 |
| SLC2A3 | 75 |
| SLC30A1 | 44 |
| SLC24A5 | -138 |
| CP | -178 |
| SLC25A10 | -273 |
| SLC36A1 | -397 |
| SLC30A10 | -569 |
| SLC17A5 | -584 |
| SLC26A2 | -594 |
| SLC2A6 | -613 |
| SLC17A7 | -678 |
| SLC13A4 | -864 |
| SLC12A2 | -875 |
| SLC2A11 | -1091 |
| SLC35A1 | -1182 |
| SLC4A3 | -1442 |
| SLC2A9 | -1499 |
| SLC25A26 | -1762 |
| SLC20A1 | -1810 |
| SLC41A2 | -1878 |
| SLC9A5 | -1886 |
| RUNX1 | -2007 |
| SLC16A10 | -2017 |
| SLC6A19 | -2122 |
| SLC26A6 | -2258 |
| RHAG | -2271 |
| SLC6A5 | -2377 |
| CALM1 | -2398 |
| SLC40A1 | -2437 |
| SLC6A20 | -2446 |
| SLC14A1 | -2459 |
| SLC22A5 | -2526 |
| SLC4A8 | -2737 |
| RHCG | -3071 |
| SLC29A4 | -3101 |
| SLC43A1 | -3118 |
| SLC30A5 | -3170 |
| SLC12A6 | -3197 |
| SLC6A18 | -3460 |
| SLC38A1 | -3477 |
| SLC11A2 | -3553 |
| SLC2A10 | -3641 |
| SLC29A1 | -3744 |
| SLC38A2 | -3799 |
| SLC9A8 | -4009 |
| SLC39A5 | -4018 |
| SLC18A2 | -4068 |
| SLC3A1 | -4322 |
| SLC16A7 | -4459 |
| SLC7A2 | -4691 |
| SLC28A2 | -4755 |
| SLC4A7 | -4815 |
| SLC39A7 | -5017 |
| SLC7A5 | -5155 |
| SLC20A2 | -5177 |
| SLC28A3 | -5369 |
| SLC22A15 | -5398 |
| SLC22A18 | -5508 |
| SLC6A3 | -6101 |
| SLC35B4 | -6180 |
| SLC33A1 | -6241 |
| SLC2A14 | -6566 |
| SLC22A1 | -6619 |
| SLC32A1 | -6820 |
| SLC12A7 | -6892 |
| SLC7A11 | -7045 |
| SLC7A1 | -7130 |
| SLC12A4 | -7271 |
| SRI | -7351 |
| SLC6A9 | -7380 |
| SLC16A1 | -7566 |
| SLC1A4 | -7598 |
| SLC26A11 | -7672 |
| SLC36A2 | -7951 |
| SLC39A6 | -8116 |
| SLC6A15 | -8139 |
| SLC16A8 | -8172 |
| SLC27A6 | -8413 |
| SLC2A8 | -8470 |
| SLC12A5 | -8572 |
| LCN1 | -8850 |
| SLC2A2 | -8932 |
| SLC25A4 | -8941 |
| RSC1A1 | -9327 |
| SLC15A2 | -9821 |
REACTOME_SUMOYLATION
| 531 | |
|---|---|
| set | REACTOME_SUMOYLATION |
| setSize | 179 |
| pANOVA | 6.37e-05 |
| s.dist | -0.173 |
| p.adjustANOVA | 0.00581 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| INCENP | -9447 |
| FOXL2 | -9444 |
| SUMO2 | -9418 |
| TFAP2C | -9348 |
| PHC1 | -9332 |
| HDAC1 | -9320 |
| TFAP2A | -9292 |
| POM121C | -9098 |
| TOP2A | -9001 |
| HERC2 | -8765 |
| SUZ12 | -8683 |
| H4C13 | -8603 |
| DDX17 | -8532 |
| NR4A2 | -8311 |
| POM121 | -8267 |
| H4C16 | -8109 |
| SAE1 | -8070 |
| PPARA | -8024 |
| NR3C2 | -7900 |
| ZNF350 | -7830 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| INCENP | -9447 |
| FOXL2 | -9444 |
| SUMO2 | -9418 |
| TFAP2C | -9348 |
| PHC1 | -9332 |
| HDAC1 | -9320 |
| TFAP2A | -9292 |
| POM121C | -9098 |
| TOP2A | -9001 |
| HERC2 | -8765 |
| SUZ12 | -8683 |
| H4C13 | -8603 |
| DDX17 | -8532 |
| NR4A2 | -8311 |
| POM121 | -8267 |
| H4C16 | -8109 |
| SAE1 | -8070 |
| PPARA | -8024 |
| NR3C2 | -7900 |
| ZNF350 | -7830 |
| RPA1 | -7755 |
| HDAC2 | -7742 |
| SATB1 | -7713 |
| PGR | -7470 |
| TDG | -7330 |
| XPC | -7228 |
| HDAC4 | -7226 |
| NUP214 | -7186 |
| EP300 | -7126 |
| DNMT3A | -7110 |
| NCOR2 | -7068 |
| NUP88 | -6865 |
| NCOA1 | -6850 |
| CBX8 | -6701 |
| XRCC4 | -6593 |
| NUP42 | -6551 |
| TRIM27 | -6522 |
| BRCA1 | -6477 |
| NR1I2 | -6423 |
| NFKBIA | -6342 |
| SAFB | -5899 |
| NUP210 | -5812 |
| NOP58 | -5810 |
| CBX4 | -5719 |
| RNF168 | -5628 |
| TPR | -5490 |
| NR3C1 | -5298 |
| NR5A2 | -5201 |
| DNMT1 | -5071 |
| CTBP1 | -4748 |
| CDKN2A | -4700 |
| NUP107 | -4561 |
| NUP50 | -4559 |
| CHD3 | -4537 |
| H4C6 | -4534 |
| NUP85 | -4358 |
| NUP98 | -4330 |
| SMC6 | -4290 |
| HIC1 | -4155 |
| WRN | -4104 |
| PHC2 | -4060 |
| NCOA2 | -4049 |
| NUP43 | -3906 |
| NUP35 | -3876 |
| H4C4 | -3867 |
| BMI1 | -3827 |
| NSMCE2 | -3736 |
| TOP2B | -3669 |
| TOP1 | -3554 |
| TOPORS | -3531 |
| NUP133 | -3446 |
| CREBBP | -3271 |
| RAD21 | -3080 |
| RING1 | -2953 |
| TFAP2B | -2839 |
| NUP188 | -2837 |
| RANGAP1 | -2606 |
| NUP205 | -2593 |
| NR1H2 | -2553 |
| H4C11 | -2488 |
| SP100 | -2471 |
| PCGF2 | -2415 |
| SENP2 | -2409 |
| VHL | -2369 |
| BIRC5 | -2354 |
| DNMT3B | -2188 |
| PML | -1804 |
| MBD1 | -1631 |
| SCMH1 | -1534 |
| SMC5 | -1178 |
| UBA2 | -993 |
| SENP5 | -948 |
| CDCA8 | -916 |
| RNF2 | -892 |
| AURKA | -876 |
| PPARGC1A | -698 |
| HNRNPK | -563 |
| TP53 | -548 |
| NUP160 | -518 |
| PARP1 | -295 |
| DDX5 | -242 |
| RAD52 | -229 |
| STAG1 | -147 |
| MDC1 | -145 |
| MRTFA | -97 |
| SATB2 | -54 |
| PCNA | -40 |
| SIN3A | -32 |
| NPM1 | 252 |
| NUP37 | 339 |
| L3MBTL2 | 443 |
| THRB | 585 |
| NR2C1 | 659 |
| PPARG | 783 |
| H4C5 | 878 |
| ZNF131 | 882 |
| SEC13 | 959 |
| RARA | 1135 |
| SMC3 | 1172 |
| SUMO3 | 1249 |
| NSMCE3 | 1250 |
| PHC3 | 1319 |
| CBX5 | 1338 |
| PARK7 | 1634 |
| NUP62 | 1710 |
| ESR1 | 1789 |
| PIAS2 | 1863 |
| HIPK2 | 1915 |
| SUMO1 | 2052 |
| SENP1 | 2164 |
| CBX2 | 2171 |
| RAE1 | 2192 |
| PIAS3 | 2421 |
| MTA1 | 2697 |
| NUP93 | 2760 |
| RORA | 2763 |
| NDC1 | 2860 |
| ING2 | 2929 |
| HDAC7 | 2984 |
| RANBP2 | 3016 |
| TP53BP1 | 3107 |
| RELA | 3308 |
| H4C8 | 3367 |
| H4C2 | 3408 |
| NRIP1 | 3416 |
| PIAS4 | 3685 |
| THRA | 3700 |
| RXRA | 3719 |
| SP3 | 3857 |
| PIAS1 | 3878 |
| BLM | 3894 |
| NUP153 | 4025 |
| NUP54 | 4170 |
| AAAS | 4254 |
| NR1H3 | 4271 |
| TRIM28 | 4273 |
| UHRF2 | 4793 |
| AURKB | 4877 |
| H4C3 | 5053 |
| NFKB2 | 5274 |
| NSMCE1 | 5318 |
| NUP58 | 5365 |
| MITF | 5434 |
| DAXX | 5566 |
| SEH1L | 5647 |
| MDM2 | 5757 |
| HNRNPC | 6281 |
| NR5A1 | 6673 |
| IKBKE | 6845 |
| UBE2I | 7189 |
| RWDD3 | 7296 |
| VDR | 7351 |
| NUP155 | 7411 |
| NR1H4 | 7526 |
| EID3 | 7968 |
| NSMCE4A | 8710 |
| H4C1 | 8782 |
| H4C9 | 9492 |
| H4C12 | 10027 |
REACTOME_DNA_REPAIR
| 1168 | |
|---|---|
| set | REACTOME_DNA_REPAIR |
| setSize | 321 |
| pANOVA | 9.21e-05 |
| s.dist | -0.127 |
| p.adjustANOVA | 0.00796 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TIMELESS | -9871.0 |
| FANCE | -9810.0 |
| YY1 | -9556.0 |
| CHEK1 | -9546.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| AQR | -9124.0 |
| PPIE | -8917.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| PALB2 | -8722.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| FAAP24 | -8398.0 |
| NSD2 | -8330.0 |
| NFRKB | -8306.0 |
| H2BC13 | -8199.0 |
| ASCC2 | -8140.0 |
| TERF1 | -8123.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TIMELESS | -9871.0 |
| FANCE | -9810.0 |
| YY1 | -9556.0 |
| CHEK1 | -9546.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| AQR | -9124.0 |
| PPIE | -8917.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| PALB2 | -8722.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| FAAP24 | -8398.0 |
| NSD2 | -8330.0 |
| NFRKB | -8306.0 |
| H2BC13 | -8199.0 |
| ASCC2 | -8140.0 |
| TERF1 | -8123.0 |
| MPG | -8111.0 |
| H4C16 | -8109.0 |
| XRCC2 | -8091.0 |
| ABRAXAS1 | -7840.0 |
| H2BC5 | -7799.0 |
| RPA1 | -7755.0 |
| UBE2L6 | -7746.0 |
| POLE | -7738.0 |
| H2AX | -7648.0 |
| RNF111 | -7646.0 |
| UFD1 | -7620.0 |
| TDP1 | -7576.0 |
| RAD18 | -7491.0 |
| PCLAF | -7475.0 |
| TOPBP1 | -7459.0 |
| ACTL6A | -7457.0 |
| POLE2 | -7447.0 |
| POLR2A | -7443.0 |
| TDG | -7330.0 |
| BRCA2 | -7322.0 |
| XPC | -7228.0 |
| FTO | -7205.0 |
| USP10 | -7138.0 |
| EP300 | -7126.0 |
| POLH | -7122.0 |
| RUVBL1 | -7114.0 |
| MGMT | -7106.0 |
| POLD2 | -7092.0 |
| MCRS1 | -7069.0 |
| SIRT6 | -7060.0 |
| XRCC6 | -6924.0 |
| ACTR5 | -6918.0 |
| ABL1 | -6881.0 |
| SMARCA5 | -6825.0 |
| RIF1 | -6761.0 |
| TOP3A | -6676.0 |
| RFC1 | -6662.0 |
| XRCC4 | -6593.0 |
| FANCL | -6546.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| PRKDC | -6492.0 |
| BRCA1 | -6477.0 |
| ALKBH5 | -6408.0 |
| POLR2K | -6386.0 |
| PAXIP1 | -6327.0 |
| POLK | -6296.0 |
| TINF2 | -6121.0 |
| GEN1 | -6109.0 |
| CUL4A | -6079.0 |
| ASCC1 | -5999.0 |
| POLQ | -5875.0 |
| FANCC | -5831.0 |
| H2AC6 | -5775.0 |
| FANCA | -5734.0 |
| FAAP100 | -5697.0 |
| H2BC15 | -5694.0 |
| PARG | -5644.0 |
| NPLOC4 | -5638.0 |
| RNF168 | -5628.0 |
| KPNA2 | -5599.0 |
| DCLRE1A | -5473.0 |
| H3-4 | -5447.0 |
| POLN | -5396.0 |
| FANCI | -5363.0 |
| ERCC5 | -5343.0 |
| H2BC6 | -5295.0 |
| KDM4A | -5242.0 |
| FANCG | -5240.0 |
| ATM | -5218.0 |
| ALKBH2 | -5170.0 |
| H2BC4 | -5066.0 |
| MUTYH | -4949.0 |
| UVSSA | -4833.0 |
| UBE2V2 | -4803.0 |
| ERCC3 | -4773.0 |
| RAD51D | -4706.0 |
| RFC5 | -4673.0 |
| UBE2T | -4653.0 |
| POLR2J | -4576.0 |
| FANCD2 | -4552.0 |
| H4C6 | -4534.0 |
| PMS2 | -4527.0 |
| RAD1 | -4483.0 |
| PARP2 | -4469.0 |
| CDK7 | -4467.0 |
| ASCC3 | -4427.0 |
| RNF8 | -4361.0 |
| PRPF19 | -4349.0 |
| DDB1 | -4266.0 |
| H2BC9 | -4255.5 |
| H2BC17 | -4192.0 |
| ISY1 | -4170.0 |
| INO80E | -4156.0 |
| POLR2B | -4142.0 |
| WRN | -4104.0 |
| RAD50 | -4035.0 |
| H4C4 | -3867.0 |
| COPS3 | -3815.0 |
| H2AJ | -3814.0 |
| POLD1 | -3772.0 |
| XRCC1 | -3716.0 |
| TERF2IP | -3592.0 |
| H2BC26 | -3582.0 |
| NEIL3 | -3578.0 |
| PPP4R2 | -3563.0 |
| LIG4 | -3340.0 |
| ERCC4 | -3260.0 |
| APBB1 | -3255.0 |
| BAP1 | -3166.0 |
| HUS1 | -3130.0 |
| VCP | -2987.0 |
| POLB | -2982.0 |
| EYA4 | -2880.0 |
| FANCF | -2753.0 |
| MSH2 | -2712.0 |
| RAD51B | -2519.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| INO80 | -2396.0 |
| POLM | -2326.0 |
| CCNH | -2298.0 |
| BABAM1 | -2123.0 |
| CLSPN | -2005.0 |
| WDR48 | -1996.0 |
| MNAT1 | -1983.0 |
| KAT5 | -1955.0 |
| GTF2H1 | -1823.0 |
| BAZ1B | -1790.0 |
| KDM4B | -1738.0 |
| ATR | -1677.0 |
| H2AC8 | -1573.0 |
| POLR2H | -1463.0 |
| DCLRE1C | -1428.0 |
| COPS7B | -1343.0 |
| POLE3 | -1337.0 |
| SLX4 | -1316.0 |
| POLD3 | -1246.0 |
| COPS7A | -1123.0 |
| RMI1 | -1065.0 |
| ELL | -1063.0 |
| APEX1 | -1061.0 |
| H2BC8 | -1029.0 |
| PPP4C | -965.0 |
| CHD1L | -946.0 |
| ATRIP | -702.0 |
| HMGN1 | -677.0 |
| TP53 | -548.0 |
| POLR2C | -541.0 |
| RAD17 | -530.0 |
| XRCC5 | -495.0 |
| COPS2 | -471.0 |
| INO80B | -379.0 |
| FAN1 | -350.0 |
| RCHY1 | -342.0 |
| H2AZ2 | -340.0 |
| PARP1 | -295.0 |
| RAD52 | -229.0 |
| UBA52 | -167.0 |
| UBE2B | -162.0 |
| MDC1 | -145.0 |
| USP43 | -139.0 |
| POLR2L | -110.0 |
| PCNA | -40.0 |
| DNA2 | -36.0 |
| PPP5C | -20.0 |
| RFC3 | -16.0 |
| REV1 | 7.0 |
| SPIDR | 112.0 |
| DTL | 137.0 |
| MAPK8 | 364.0 |
| POT1 | 546.0 |
| XPA | 756.0 |
| PNKP | 802.0 |
| ERCC2 | 803.0 |
| CENPS | 874.0 |
| H4C5 | 878.0 |
| RAD51 | 905.0 |
| RFC4 | 973.0 |
| MSH3 | 1008.0 |
| BABAM2 | 1018.0 |
| REV3L | 1020.0 |
| USP1 | 1027.0 |
| ACTR8 | 1139.0 |
| RPA2 | 1210.0 |
| POLL | 1222.0 |
| POLI | 1240.0 |
| SUMO3 | 1249.0 |
| FAAP20 | 1404.0 |
| NHEJ1 | 1484.0 |
| ZNF830 | 1501.0 |
| COPS8 | 1516.0 |
| MAD2L2 | 1582.0 |
| POLR2E | 1649.0 |
| USP45 | 1793.0 |
| SEM1 | 1794.0 |
| DDB2 | 1829.0 |
| RPS27A | 1846.0 |
| TERF2 | 1872.0 |
| H2BC3 | 1920.0 |
| SUMO1 | 2052.0 |
| COPS5 | 2087.0 |
| RAD51C | 2354.0 |
| ALKBH3 | 2355.0 |
| EXO1 | 2396.0 |
| PIAS3 | 2421.0 |
| MUS81 | 2574.0 |
| TRIM25 | 2692.0 |
| H2BC1 | 2755.0 |
| FEN1 | 2933.0 |
| FANCM | 2970.0 |
| MLH1 | 3003.0 |
| BRIP1 | 3028.0 |
| RAD23B | 3038.0 |
| TP53BP1 | 3107.0 |
| EYA1 | 3139.0 |
| RTEL1 | 3221.0 |
| INO80C | 3272.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| RMI2 | 3423.0 |
| UIMC1 | 3452.0 |
| MBD4 | 3459.0 |
| GPS1 | 3470.0 |
| NBN | 3478.0 |
| SPRTN | 3615.0 |
| DCLRE1B | 3652.0 |
| PIAS4 | 3685.0 |
| NTHL1 | 3725.0 |
| TIPIN | 3874.0 |
| PIAS1 | 3878.0 |
| BLM | 3894.0 |
| NEIL1 | 4131.0 |
| XAB2 | 4144.0 |
| ERCC8 | 4217.0 |
| RFC2 | 4313.0 |
| ACD | 4346.5 |
| CCNA2 | 4366.0 |
| RPA3 | 4481.0 |
| EYA3 | 4781.0 |
| POLR2I | 4862.0 |
| UBE2N | 4905.0 |
| UBXN1 | 4957.0 |
| H4C3 | 5053.0 |
| UNG | 5064.0 |
| TFPT | 5101.0 |
| ACTB | 5155.0 |
| CDK2 | 5165.0 |
| EME1 | 5291.0 |
| ADPRS | 5292.0 |
| GTF2H3 | 5295.0 |
| EME2 | 5376.0 |
| MRE11 | 5531.0 |
| GTF2H5 | 5585.0 |
| USP7 | 5667.0 |
| RAD9A | 5759.0 |
| POLD4 | 6046.0 |
| RNF4 | 6134.0 |
| XRCC3 | 6155.0 |
| INO80D | 6156.0 |
| GTF2H4 | 6387.0 |
| H2BC11 | 6454.0 |
| UBC | 6700.0 |
| RAD9B | 6859.0 |
| ERCC6 | 6897.0 |
| H2AC4 | 6905.0 |
| EYA2 | 7010.0 |
| UBE2I | 7189.0 |
| NEIL2 | 7233.0 |
| TCEA1 | 7385.0 |
| H2BC21 | 7408.0 |
| CHEK2 | 7446.0 |
| SMUG1 | 7582.0 |
| RAD51AP1 | 7593.0 |
| UBB | 7594.0 |
| H2BC12 | 7676.0 |
| COPS4 | 7773.0 |
| TDP2 | 7875.0 |
| MSH6 | 8044.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| ERCC1 | 8264.0 |
| POLR2D | 8323.0 |
| UBA7 | 8419.0 |
| POLE4 | 8577.0 |
| H2AC20 | 8750.0 |
| COPS6 | 8762.0 |
| H4C1 | 8782.0 |
| POLR2F | 8864.0 |
| H2AZ1 | 8917.0 |
| OGG1 | 8927.0 |
| LIG1 | 8960.0 |
| POLR2G | 9208.0 |
| ISG15 | 9216.0 |
| RAD23A | 9233.0 |
| H2AC14 | 9376.0 |
| H4C9 | 9492.0 |
| H4C12 | 10027.0 |
| LIG3 | 10147.0 |
| H2BC14 | 10168.0 |
| RBX1 | 10301.0 |
REACTOME_INTERLEUKIN_10_SIGNALING
| 1039 | |
|---|---|
| set | REACTOME_INTERLEUKIN_10_SIGNALING |
| setSize | 43 |
| pANOVA | 0.000111 |
| s.dist | 0.341 |
| p.adjustANOVA | 0.0091 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL4 | 11339 |
| FCER2 | 11295 |
| CCL3 | 11173 |
| CD86 | 10985 |
| CD80 | 10976 |
| CSF3 | 10760 |
| IL1A | 10585 |
| CSF2 | 10380 |
| CCL19 | 10278 |
| CCR2 | 9871 |
| CCL2 | 9673 |
| TNFRSF1A | 9652 |
| PTAFR | 9482 |
| TNF | 9392 |
| CCR5 | 9293 |
| ICAM1 | 9224 |
| CCL22 | 8716 |
| CXCL8 | 8674 |
| STAT3 | 7887 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL4 | 11339 |
| FCER2 | 11295 |
| CCL3 | 11173 |
| CD86 | 10985 |
| CD80 | 10976 |
| CSF3 | 10760 |
| IL1A | 10585 |
| CSF2 | 10380 |
| CCL19 | 10278 |
| CCR2 | 9871 |
| CCL2 | 9673 |
| TNFRSF1A | 9652 |
| PTAFR | 9482 |
| TNF | 9392 |
| CCR5 | 9293 |
| ICAM1 | 9224 |
| CCL22 | 8716 |
| CXCL8 | 8674 |
| STAT3 | 7887 |
| CSF1 | 7581 |
| FPR1 | 7228 |
| IL1RN | 6910 |
| JAK1 | 6368 |
| IL12A | 4664 |
| LIF | 4365 |
| IL12B | 3708 |
| IL1R1 | 3432 |
| IL10RA | 2828 |
| CCL20 | 1795 |
| CXCL1 | -394 |
| TYK2 | -1265 |
| TNFRSF1B | -1551 |
| CCR1 | -2124 |
| CXCL2 | -3545 |
| IL10 | -4524 |
| IL1R2 | -4708 |
| CXCL10 | -7168 |
| IL1B | -7175 |
| PTGS2 | -7471 |
| IL6 | -8175 |
| IL18 | -8726 |
| IL10RB | -8832 |
REACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III
| 1528 | |
|---|---|
| set | REACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III |
| setSize | 31 |
| pANOVA | 0.000118 |
| s.dist | -0.4 |
| p.adjustANOVA | 0.0092 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| TUBA3E | -8293 |
| CHMP4C | -7757 |
| CHMP4B | -7159 |
| SPAST | -7098 |
| TUBA4A | -6626 |
| TUBB2B | -6314 |
| TUBB2A | -5979 |
| CHMP2A | -5098 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CHMP3 | -4842 |
| TUBA1B | -4624 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| TUBA3E | -8293 |
| CHMP4C | -7757 |
| CHMP4B | -7159 |
| SPAST | -7098 |
| TUBA4A | -6626 |
| TUBB2B | -6314 |
| TUBB2A | -5979 |
| CHMP2A | -5098 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CHMP3 | -4842 |
| TUBA1B | -4624 |
| TUBA8 | -4032 |
| TUBA1A | -1819 |
| CHMP7 | -1636 |
| IST1 | 123 |
| TUBB1 | 1069 |
| TUBA3C | 3214 |
| TUBB6 | 3539 |
| TUBB4A | 3612 |
| TUBB3 | 6221 |
| CHMP6 | 7265 |
| TUBB8 | 11325 |
REACTOME_BIOLOGICAL_OXIDATIONS
| 427 | |
|---|---|
| set | REACTOME_BIOLOGICAL_OXIDATIONS |
| setSize | 210 |
| pANOVA | 0.000135 |
| s.dist | 0.153 |
| p.adjustANOVA | 0.0101 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11544 |
| GSTA1 | 11431 |
| ADH7 | 11354 |
| SLC35B2 | 11311 |
| AOC1 | 11215 |
| CYP4B1 | 11208 |
| CYP2B6 | 11159 |
| ADH1B | 11119 |
| ADH1A | 11059 |
| NAT2 | 11037 |
| UGT2A2 | 10827 |
| CES3 | 10801 |
| SULT6B1 | 10762 |
| MAT1A | 10736 |
| GSTP1 | 10683 |
| AOC3 | 10673 |
| GLYAT | 10656 |
| CYP8B1 | 10636 |
| FDX2 | 10627 |
| CYP1A2 | 10609 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11544 |
| GSTA1 | 11431 |
| ADH7 | 11354 |
| SLC35B2 | 11311 |
| AOC1 | 11215 |
| CYP4B1 | 11208 |
| CYP2B6 | 11159 |
| ADH1B | 11119 |
| ADH1A | 11059 |
| NAT2 | 11037 |
| UGT2A2 | 10827 |
| CES3 | 10801 |
| SULT6B1 | 10762 |
| MAT1A | 10736 |
| GSTP1 | 10683 |
| AOC3 | 10673 |
| GLYAT | 10656 |
| CYP8B1 | 10636 |
| FDX2 | 10627 |
| CYP1A2 | 10609 |
| UGT2A1 | 10466 |
| ALDH2 | 10448 |
| CYP2C9 | 10234 |
| CYP3A43 | 10049 |
| UGT3A1 | 9985 |
| CYP2W1 | 9952 |
| CYP11A1 | 9921 |
| CYP4F12 | 9919 |
| CYP4A22 | 9874 |
| UGT2B7 | 9872 |
| GGT6 | 9850 |
| ARNT2 | 9786 |
| GSS | 9626 |
| GSTA2 | 9521 |
| CYP2A13 | 9483 |
| GGCT | 9301 |
| COMT | 9288 |
| AADAC | 9207 |
| GSTO2 | 9173 |
| FMO3 | 8931 |
| SULT1A2 | 8913 |
| ALDH3A1 | 8775 |
| AKR7A2 | 8670 |
| ABHD14B | 8597 |
| GSTM3 | 8549 |
| DPEP2 | 8382 |
| AIP | 8261 |
| SULT1E1 | 8084 |
| ACY1 | 8071 |
| CYP2R1 | 7985 |
| ACSM2A | 7859 |
| ALDH1B1 | 7852 |
| CYP2C19 | 7814 |
| NR1H4 | 7526 |
| CYP3A4 | 7504 |
| SMOX | 7477 |
| CHAC1 | 7225 |
| ACSM4 | 7204 |
| FDX1 | 7183 |
| GGT1 | 7037 |
| GCLM | 7015 |
| TPST1 | 6892 |
| ABHD10 | 6889 |
| CYP4F8 | 6817 |
| MAT2A | 6727 |
| FMO1 | 6664 |
| SULT1A1 | 6592 |
| CES1 | 6457 |
| AHR | 6179 |
| GSTA4 | 5995 |
| CYP51A1 | 5789 |
| EPHX1 | 5504 |
| CYP19A1 | 5423 |
| TRMT112 | 5339 |
| FMO2 | 5269 |
| CYP1A1 | 5175 |
| SULT1C2 | 4857 |
| SLC26A1 | 4462 |
| UGT2B4 | 4445 |
| CYP1B1 | 4443 |
| GSTO1 | 4290 |
| UGT2B17 | 4284 |
| ACSS2 | 4137 |
| GSTM4 | 4082 |
| CYP4F22 | 4047 |
| PAOX | 4022 |
| OPLAH | 3791 |
| RXRA | 3719 |
| ACY3 | 3691 |
| ACSM5 | 3596 |
| CYP11B2 | 3493 |
| GSTK1 | 3387 |
| ADH4 | 3292 |
| MTARC2 | 3227 |
| CYP26A1 | 2987 |
| GSTM5 | 2710 |
| GSTA3 | 2675 |
| GSTZ1 | 2484 |
| CNDP2 | 2362 |
| ARNT | 2360 |
| PAPSS2 | 2166 |
| ACSM2B | 2137 |
| CYP2D6 | 2094 |
| GGT7 | 1818 |
| MAT2B | 1768 |
| PTGIS | 1745 |
| UGP2 | 1650 |
| AHCY | 1648 |
| CYP2J2 | 1596 |
| CYP3A7 | 1562 |
| CYP2A7 | 1552 |
| CYP7A1 | 1536 |
| GLYATL3 | 1495 |
| AKR7A3 | 1295 |
| SLC35B3 | 1194 |
| GLYATL2 | 1166 |
| CYP2F1 | 1107 |
| SULT2B1 | 1046 |
| CYP2C18 | 1021 |
| GGT5 | 997 |
| SLC35D1 | 587 |
| GCLC | 574 |
| ACSM1 | 438 |
| CYP27B1 | 369 |
| ESD | 206 |
| UGT1A6 | 186 |
| ALDH1A1 | 176 |
| UGT2B15 | 65 |
| SULT1B1 | 11 |
| CYB5R3 | 1 |
| BPHL | -283 |
| GLYATL1 | -313 |
| CMBL | -330 |
| POR | -491 |
| MTR | -506 |
| NQO2 | -507 |
| GSTM1 | -579 |
| SLC26A2 | -594 |
| ADH1C | -603 |
| TBXAS1 | -752 |
| CBR3 | -790 |
| POMC | -950 |
| CYP7B1 | -958 |
| CYP2E1 | -1388 |
| MGST1 | -1479 |
| MTRR | -1502 |
| BPNT1 | -1515 |
| PTGES3 | -1520 |
| AKR1A1 | -1714 |
| UGT1A8 | -1740 |
| CYP46A1 | -1744 |
| CYP11B1 | -1803 |
| UGT1A4 | -1863 |
| MGST3 | -1912 |
| UGT1A7 | -2049 |
| CYP26C1 | -2144 |
| FDXR | -2175 |
| TPST2 | -2186 |
| CYP2S1 | -2207 |
| UGT1A10 | -2218 |
| UGT1A9 | -2235 |
| DPEP1 | -2268 |
| CES2 | -2290 |
| PAPSS1 | -2389 |
| CYP4A11 | -2572 |
| AKR7L | -2604 |
| MGST2 | -2884 |
| UGT1A1 | -2946 |
| PTGS1 | -3067 |
| AOC2 | -3110 |
| CHAC2 | -3785 |
| NCOA2 | -4049 |
| UGT1A5 | -4077 |
| MTARC1 | -4115 |
| HSP90AB1 | -4117 |
| UGT2B11 | -4259 |
| UGT1A3 | -4295 |
| TPMT | -4470 |
| SULT1C4 | -4630 |
| ADH5 | -4893 |
| N6AMT1 | -5036 |
| CYP4V2 | -5039 |
| CYP4F11 | -5304 |
| CYP2U1 | -5360 |
| CYP4F3 | -5672 |
| PODXL2 | -5786 |
| HPGDS | -6051 |
| NNMT | -6262 |
| CYP26B1 | -6362 |
| CYB5B | -6437 |
| NCOA1 | -6850 |
| NAT1 | -6919 |
| GSTM2 | -7100 |
| DPEP3 | -7108 |
| UGDH | -7151 |
| BPNT2 | -7194 |
| SULT2A1 | -7463 |
| CYP24A1 | -7506 |
| CYP39A1 | -7639 |
| CYP2C8 | -7814 |
| CYP27A1 | -7971 |
| UGT2A3 | -8295 |
| ACSS1 | -8369 |
| SULT4A1 | -8563 |
| GSTA5 | -8745 |
| AS3MT | -9002 |
| ADH6 | -9609 |
| UGT3A2 | -9777 |
| CYP3A5 | -9931 |
| CYP4F2 | -10007 |
REACTOME_TRANSPORT_OF_SMALL_MOLECULES
| 630 | |
|---|---|
| set | REACTOME_TRANSPORT_OF_SMALL_MOLECULES |
| setSize | 697 |
| pANOVA | 0.000176 |
| s.dist | 0.0834 |
| p.adjustANOVA | 0.0126 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| APOC3 | 11415 |
| LCN2 | 11357 |
| SLC35B2 | 11311 |
| SLC34A1 | 11198 |
| AQP6 | 11190 |
| FGF21 | 11156 |
| SLC2A7 | 11144 |
| TRPM5 | 11038 |
| AQP10 | 11027 |
| LCN9 | 10977 |
| CIDEC | 10965 |
| TRPV6 | 10964 |
| GNGT1 | 10937 |
| SLC22A11 | 10910 |
| SLC7A7 | 10890 |
| ABCC6 | 10889 |
| APOA4 | 10814 |
| CES3 | 10801 |
| GNG8 | 10795 |
| SLC5A12 | 10779 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| APOC3 | 11415 |
| LCN2 | 11357 |
| SLC35B2 | 11311 |
| SLC34A1 | 11198 |
| AQP6 | 11190 |
| FGF21 | 11156 |
| SLC2A7 | 11144 |
| TRPM5 | 11038 |
| AQP10 | 11027 |
| LCN9 | 10977 |
| CIDEC | 10965 |
| TRPV6 | 10964 |
| GNGT1 | 10937 |
| SLC22A11 | 10910 |
| SLC7A7 | 10890 |
| ABCC6 | 10889 |
| APOA4 | 10814 |
| CES3 | 10801 |
| GNG8 | 10795 |
| SLC5A12 | 10779 |
| SLC7A9 | 10727 |
| SLC6A7 | 10701 |
| LCN12 | 10601 |
| SLC39A4 | 10572 |
| TRPM3 | 10566 |
| SLCO1C1 | 10539 |
| FXYD4 | 10538 |
| FTL | 10533 |
| AZGP1 | 10527 |
| CYB5R1 | 10510 |
| AQP3 | 10374 |
| PRKAR2A | 10361 |
| SLC16A3 | 10351 |
| ATP10B | 10328 |
| CAMK2A | 10289 |
| CASQ1 | 10247 |
| SLC13A1 | 10198 |
| TRDN | 10181 |
| BSG | 10115 |
| SLCO2B1 | 10058 |
| SOAT2 | 10057 |
| SLC45A3 | 10006 |
| AQP12A | 9975 |
| SLC38A3 | 9973 |
| SLC34A3 | 9961 |
| SLC13A5 | 9909 |
| SLCO1A2 | 9908 |
| BEST2 | 9866 |
| PSME1 | 9765 |
| SLC4A9 | 9733 |
| AQP1 | 9681 |
| LPA | 9660 |
| ATP7B | 9655 |
| PSMA7 | 9563 |
| SLC5A4 | 9554 |
| SLC30A2 | 9525 |
| ANO8 | 9487 |
| GNG13 | 9443 |
| GNB3 | 9437 |
| SLC18A1 | 9432 |
| SLC5A1 | 9427 |
| SLC46A1 | 9413 |
| ABCA6 | 9402 |
| SLC26A3 | 9401 |
| SLC6A12 | 9380 |
| CYB5R2 | 9372 |
| SLC43A2 | 9371 |
| CETP | 9370 |
| SLC14A2 | 9283 |
| SLC26A7 | 9262 |
| ABCC9 | 9261 |
| ADCY5 | 9251 |
| SLC34A2 | 9194 |
| LCN15 | 9178 |
| APOA5 | 9156 |
| SLC44A4 | 9128 |
| SLC22A4 | 9097 |
| CAMK2G | 9035 |
| ATP6V1B1 | 8963 |
| YME1L1 | 8947 |
| SLC22A6 | 8942 |
| SLC12A3 | 8909 |
| LSR | 8894 |
| ABCC3 | 8825 |
| FXYD2 | 8754 |
| BSND | 8742 |
| SLC30A3 | 8737 |
| ANO7 | 8713 |
| SLC66A1 | 8688 |
| SLCO4A1 | 8680 |
| MYLIP | 8675 |
| TRPV3 | 8652 |
| TRPC7 | 8619 |
| ATP1B1 | 8466 |
| MYO5B | 8422 |
| ATP6V0C | 8420 |
| SLC15A4 | 8416 |
| MRS2 | 8400 |
| STEAP3 | 8366 |
| SAR1B | 8361 |
| SLC5A11 | 8359 |
| ASIC1 | 8274 |
| ATP6V1E2 | 8273 |
| ANO2 | 8254 |
| SLC13A2 | 8232 |
| CLCN1 | 8203 |
| SLC27A4 | 8132 |
| SLC11A1 | 8130 |
| PIP | 8106 |
| TFR2 | 8102 |
| GNGT2 | 8088 |
| SLC4A4 | 8049 |
| SLCO4C1 | 8026 |
| ASIC5 | 8021 |
| PSMB3 | 8017 |
| SLC24A3 | 8014 |
| CA1 | 8007 |
| ABCG4 | 7983 |
| SLC28A1 | 7962 |
| SLC26A4 | 7952 |
| SLC2A1 | 7922 |
| P4HB | 7917 |
| ABCG1 | 7905 |
| TTYH2 | 7841 |
| MFSD4B | 7811 |
| SLC4A10 | 7794 |
| SLC31A1 | 7780 |
| TRPM4 | 7775 |
| FXYD7 | 7756 |
| PCSK6 | 7678 |
| SLC26A9 | 7666 |
| ATP2B2 | 7660 |
| SLC25A18 | 7639 |
| UBB | 7594 |
| SLC22A7 | 7589 |
| HMOX1 | 7583 |
| PSMA4 | 7568 |
| SLC2A4 | 7564 |
| CASQ2 | 7489 |
| RYR2 | 7478 |
| SLC30A8 | 7469 |
| SLC39A3 | 7459 |
| ATP12A | 7417 |
| SLC44A1 | 7413 |
| SLC5A7 | 7406 |
| SLC22A16 | 7384 |
| ATP2A1 | 7381 |
| ABCA2 | 7262 |
| ATP6V0D2 | 7246 |
| FURIN | 7240 |
| PHB2 | 7230 |
| ATP4B | 7227 |
| SLC25A22 | 7177 |
| STOML3 | 7171 |
| SLC35C1 | 7138 |
| ATP4A | 7131 |
| ADCY6 | 7056 |
| ERLIN2 | 7045 |
| ABCA10 | 7031 |
| AQP8 | 6993 |
| PSMA6 | 6984 |
| SLC24A1 | 6937 |
| FTMT | 6898 |
| ATP13A5 | 6834 |
| SLC44A5 | 6803 |
| CYGB | 6798 |
| ABCA4 | 6785 |
| ACO1 | 6777 |
| ABCB8 | 6773 |
| UBC | 6700 |
| SLC1A5 | 6642 |
| PSME2 | 6638 |
| GNG5 | 6619 |
| PSMD6 | 6616 |
| APOC2 | 6566 |
| PCSK5 | 6556 |
| ABCB9 | 6533 |
| PSMA8 | 6502 |
| SLC1A6 | 6386 |
| MIP | 6359 |
| ANGPTL4 | 6335 |
| ATP6V0A1 | 6264 |
| APOBR | 6212 |
| PRKACA | 6168 |
| ZDHHC8 | 6167 |
| SLC50A1 | 6124 |
| SLC4A5 | 6121 |
| DERL3 | 6103 |
| FXYD6 | 6101 |
| SLC22A8 | 6079 |
| TRPM2 | 6036 |
| CSN3 | 6023 |
| ANO1 | 6020 |
| SCNN1B | 5903 |
| SLC15A1 | 5880 |
| PSMB7 | 5858 |
| CLCNKB | 5804 |
| PSMB2 | 5803 |
| ATP1B2 | 5792 |
| CFTR | 5784 |
| SLC5A2 | 5752 |
| SLC5A10 | 5648 |
| STOM | 5645 |
| ATP10D | 5594 |
| SLC8B1 | 5579 |
| SGK2 | 5562 |
| SLC47A1 | 5517 |
| SLC2A13 | 5513 |
| SLC7A6 | 5467 |
| SLC17A1 | 5453 |
| SLC1A2 | 5390 |
| GNG4 | 5377 |
| SLC39A14 | 5333 |
| FXYD1 | 5329 |
| ANO9 | 5326 |
| ADD3 | 5310 |
| PSMD7 | 5305 |
| ATP6V1E1 | 5273 |
| RHBG | 5244 |
| PSMF1 | 5221 |
| HBB | 5191 |
| SLC22A3 | 5185 |
| MB | 5032 |
| CAMK2B | 4977 |
| PSMB4 | 4971 |
| KCNJ11 | 4955 |
| SLCO1B1 | 4937 |
| ADCY1 | 4852 |
| SLC1A1 | 4850 |
| SLC4A1 | 4842 |
| ARL2 | 4840 |
| ATP1A1 | 4818 |
| SLC24A2 | 4772 |
| VDAC2 | 4743 |
| BEST4 | 4729 |
| SLC9A9 | 4646 |
| SLC9A1 | 4618 |
| SLC7A10 | 4523 |
| CYBRD1 | 4506 |
| DERL2 | 4498 |
| ABCA12 | 4491 |
| SLC5A9 | 4476 |
| SLC26A1 | 4462 |
| SLC7A8 | 4413 |
| CUL1 | 4399 |
| SLC24A4 | 4393 |
| SLC39A10 | 4363 |
| SLN | 4318 |
| NR1H3 | 4271 |
| PEX3 | 4220 |
| ABCC11 | 4180 |
| SLC25A29 | 4176 |
| ABCC2 | 4129 |
| TRPC1 | 4118 |
| EIF2S1 | 4095 |
| NEDD8 | 4083 |
| PRKAR2B | 4071 |
| ATP13A2 | 4066 |
| PMPCB | 4019 |
| AQP4 | 4005 |
| TRPM6 | 3932 |
| TRPV4 | 3925 |
| ATP11B | 3913 |
| GNG7 | 3838 |
| RNF185 | 3832 |
| ALB | 3805 |
| VDAC1 | 3778 |
| SLC10A6 | 3709 |
| ABCD3 | 3702 |
| ASIC2 | 3675 |
| SLC39A2 | 3659 |
| SLC39A8 | 3649 |
| AVP | 3646 |
| SLC8A1 | 3640 |
| TCIRG1 | 3585 |
| SLCO2A1 | 3550 |
| SLC12A1 | 3519 |
| SLC6A1 | 3471 |
| SLC9A4 | 3468 |
| ARL2BP | 3430 |
| ABCB4 | 3419 |
| ABCG2 | 3410 |
| SLC6A13 | 3391 |
| ADCY8 | 3376 |
| WNK2 | 3369 |
| ABCD2 | 3346 |
| APOD | 3339 |
| SLC8A3 | 3327 |
| SLC2A12 | 3325 |
| FKBP1B | 3324 |
| SLC22A2 | 3319 |
| SOAT1 | 3246 |
| ASIC3 | 3236 |
| SLC1A7 | 3235 |
| AHCYL2 | 3189 |
| ANO4 | 3181 |
| BEST3 | 3060 |
| PRKAR1A | 3042 |
| SLC29A3 | 3032 |
| ABCG8 | 2991 |
| CLCN3 | 2973 |
| SMDT1 | 2971 |
| ADCY9 | 2936 |
| GPIHBP1 | 2894 |
| ABCA3 | 2864 |
| TRPA1 | 2862 |
| ANO3 | 2855 |
| NALCN | 2847 |
| CAMK2D | 2790 |
| SLC4A2 | 2775 |
| SLC6A6 | 2756 |
| PHB1 | 2751 |
| CLCN2 | 2711 |
| DMTN | 2685 |
| ADCY3 | 2673 |
| CLCN6 | 2632 |
| APOC4 | 2576 |
| ATP6V1D | 2482 |
| SLC17A6 | 2476 |
| SLC35D2 | 2418 |
| SLC5A8 | 2334 |
| ANGPTL8 | 2323 |
| SGK3 | 2279 |
| SLC9C1 | 2260 |
| PSMD8 | 2235 |
| NPC2 | 2222 |
| AFG3L2 | 2216 |
| PSMC5 | 2183 |
| DERL1 | 2160 |
| SCNN1A | 2148 |
| SLC27A1 | 2104 |
| SLC44A2 | 2080 |
| TRPC4 | 2074 |
| ATP8A2 | 2037 |
| CA2 | 1991 |
| SLC9B2 | 1960 |
| ATP6V1F | 1958 |
| SLC29A2 | 1932 |
| ASIC4 | 1929 |
| OS9 | 1869 |
| ADCY4 | 1849 |
| RPS27A | 1846 |
| SLC5A6 | 1830 |
| SLC35A3 | 1815 |
| SEM1 | 1794 |
| TTYH3 | 1766 |
| ATP6V1A | 1763 |
| SLC6A2 | 1742 |
| ABCB1 | 1740 |
| CTNS | 1704 |
| SLC15A3 | 1702 |
| SLC17A8 | 1673 |
| CLCA1 | 1665 |
| SLC44A3 | 1642 |
| NIPAL1 | 1630 |
| ATP2B4 | 1528 |
| SLCO3A1 | 1505 |
| SLC13A3 | 1491 |
| SLC41A1 | 1461 |
| ABCC1 | 1428 |
| ADCY2 | 1392 |
| SLC36A4 | 1345 |
| PLTP | 1292 |
| ATP8B2 | 1291 |
| CREB3L3 | 1234 |
| PSMD14 | 1213 |
| ATP1A4 | 1204 |
| MCOLN1 | 1198 |
| SLC35B3 | 1194 |
| SLCO1B3 | 1148 |
| LDLRAP1 | 1124 |
| ABCG5 | 1115 |
| SLC5A3 | 1061 |
| MLKL | 990 |
| RIPK3 | 975 |
| SLC22A12 | 921 |
| EMB | 914 |
| GNG2 | 908 |
| PSMD12 | 901 |
| SLC47A2 | 865 |
| ATP6V1G2 | 776 |
| ATP2A3 | 772 |
| ATP10A | 749 |
| SLC1A3 | 708 |
| ASPH | 702 |
| CSN1S1 | 627 |
| SLC35D1 | 587 |
| RYR3 | 577 |
| NEDD4L | 548 |
| SLC9A3 | 540 |
| SCARB1 | 518 |
| SLC3A2 | 490 |
| PSMB10 | 447 |
| APOC1 | 404 |
| AKAP1 | 353 |
| SLC38A4 | 351 |
| TRPM8 | 318 |
| SLC6A11 | 296 |
| ATP9A | 269 |
| SLC9A2 | 214 |
| ATP1B3 | 172 |
| ATP6V0B | 148 |
| APOA1 | 129 |
| SLC5A5 | 127 |
| SLC8A2 | 122 |
| GNG11 | 104 |
| SLC39A1 | 99 |
| SLC2A3 | 75 |
| FTH1 | 57 |
| SLC30A1 | 44 |
| TPCN1 | 32 |
| MBTPS1 | -25 |
| MCOLN3 | -70 |
| ADD2 | -116 |
| SLC24A5 | -138 |
| ANGPTL3 | -140 |
| ABCB6 | -148 |
| UBA52 | -167 |
| CP | -178 |
| PSMB8 | -260 |
| SKP1 | -264 |
| SLC25A10 | -273 |
| PMPCA | -393 |
| SLC36A1 | -397 |
| GNG12 | -413 |
| ERLIN1 | -414 |
| RYR1 | -422 |
| LIPC | -426 |
| TRPM7 | -444 |
| AQP5 | -454 |
| PSMA1 | -477 |
| SLC30A10 | -569 |
| SLC17A5 | -584 |
| SCNN1D | -588 |
| SLC26A2 | -594 |
| PCSK9 | -608 |
| SLC2A6 | -613 |
| SEL1L | -644 |
| SLC17A7 | -678 |
| AP2M1 | -688 |
| ABCA5 | -695 |
| LRRC8E | -718 |
| AMN | -793 |
| SLC13A4 | -864 |
| SLC12A2 | -875 |
| WNK1 | -903 |
| SPG7 | -914 |
| CLTC | -931 |
| ABCB10 | -962 |
| AQP11 | -966 |
| MTTP | -986 |
| GNG3 | -991 |
| SLC9C2 | -1082 |
| SLC2A11 | -1091 |
| PSME3 | -1153 |
| BMP1 | -1162 |
| SLC35A1 | -1182 |
| FLVCR1 | -1240 |
| ABCC5 | -1248 |
| CUBN | -1256 |
| CLCA2 | -1294 |
| OSTM1 | -1320 |
| PSMA3 | -1391 |
| SLC4A3 | -1442 |
| ATP2C2 | -1459 |
| FXYD3 | -1476 |
| SLC2A9 | -1499 |
| SLC9B1 | -1519 |
| ATP6V1B2 | -1556 |
| ABCA7 | -1626 |
| PSMB9 | -1684 |
| SLC25A26 | -1762 |
| RAF1 | -1766 |
| ATP2B1 | -1805 |
| SLC20A1 | -1810 |
| SLC41A2 | -1878 |
| SLC9A5 | -1886 |
| STOML2 | -1910 |
| ATP6V0A4 | -1943 |
| NIPAL4 | -1963 |
| GLRX3 | -2003 |
| RUNX1 | -2007 |
| SLC16A10 | -2017 |
| NGB | -2085 |
| TRPM1 | -2093 |
| SLC6A19 | -2122 |
| PSMC6 | -2126 |
| SLC26A6 | -2258 |
| RHAG | -2271 |
| MCU | -2316 |
| SGK1 | -2322 |
| SLC6A5 | -2377 |
| CLTA | -2384 |
| CALM1 | -2398 |
| SLC40A1 | -2437 |
| SLC6A20 | -2446 |
| SLC14A1 | -2459 |
| PSMA2 | -2485 |
| GNB2 | -2516 |
| SLC22A5 | -2526 |
| TF | -2545 |
| NR1H2 | -2553 |
| GNG10 | -2641 |
| TPCN2 | -2723 |
| SLC4A8 | -2737 |
| LIPG | -2761 |
| PSMB1 | -2799 |
| ABCF1 | -2808 |
| ABCA8 | -2890 |
| VCP | -2987 |
| CUTC | -2999 |
| LIPA | -3013 |
| GNB1 | -3044 |
| RHCG | -3071 |
| PSMC4 | -3089 |
| SLC29A4 | -3101 |
| SLC43A1 | -3118 |
| ADCY7 | -3144 |
| ADD1 | -3157 |
| SCNN1G | -3163 |
| SLC30A5 | -3170 |
| SLC12A6 | -3197 |
| APOE | -3335 |
| MCOLN2 | -3406 |
| ABCA9 | -3413 |
| SLC6A18 | -3460 |
| SLC38A1 | -3477 |
| SLC11A2 | -3553 |
| TRPV1 | -3623 |
| SLC2A10 | -3641 |
| CYB5R4 | -3703 |
| AP2B1 | -3712 |
| SLC29A1 | -3744 |
| UNC79 | -3796 |
| SLC38A2 | -3799 |
| ATP6V0A2 | -3810 |
| WNK4 | -3829 |
| PSMD1 | -3979 |
| CLCA4 | -3992 |
| GNB5 | -4000 |
| SLC9A8 | -4009 |
| SLC39A5 | -4018 |
| MICU3 | -4038 |
| SLC18A2 | -4068 |
| ABCA1 | -4075 |
| LMF1 | -4181 |
| MCUB | -4196 |
| LRRC8D | -4211 |
| AP2A2 | -4220 |
| ANO6 | -4225 |
| PSMB6 | -4271 |
| A2M | -4297 |
| SLC3A1 | -4322 |
| ABCC4 | -4397 |
| SLC16A7 | -4459 |
| ATP8B3 | -4530 |
| UNC80 | -4597 |
| ATP2C1 | -4608 |
| SLC7A2 | -4691 |
| PSMD5 | -4711 |
| SLC28A2 | -4755 |
| SLC4A7 | -4815 |
| PSMA5 | -4888 |
| AP2A1 | -4940 |
| CA4 | -4990 |
| BEST1 | -5000 |
| SLC39A7 | -5017 |
| TTYH1 | -5050 |
| PSME4 | -5053 |
| AP2S1 | -5086 |
| MICU1 | -5090 |
| SLC7A5 | -5155 |
| SLC20A2 | -5177 |
| HDLBP | -5189 |
| PSMC3 | -5262 |
| WWP1 | -5266 |
| MAIP1 | -5268 |
| ABCB5 | -5283 |
| ATP6V0E1 | -5354 |
| SLC28A3 | -5369 |
| HMOX2 | -5379 |
| SLC22A15 | -5398 |
| CLCN7 | -5454 |
| SLC22A18 | -5508 |
| NIPAL2 | -5537 |
| TFRC | -5540 |
| VLDLR | -5594 |
| FBXL5 | -5705 |
| CYB5RL | -5728 |
| ATP6V1C2 | -5758 |
| LDLR | -5785 |
| ERLEC1 | -5798 |
| CAND1 | -5838 |
| ATP13A4 | -5862 |
| VDAC3 | -5884 |
| RNF5 | -5890 |
| ABCC10 | -5921 |
| ATP6V1G1 | -5938 |
| ATP1A3 | -5943 |
| ANO5 | -5951 |
| ATP8B1 | -6008 |
| NPC1 | -6016 |
| PSMC2 | -6032 |
| PSMD11 | -6044 |
| SLC6A3 | -6101 |
| ATP8B4 | -6135 |
| SLC35B4 | -6180 |
| TRPC3 | -6233 |
| LRRC8A | -6237 |
| SLC33A1 | -6241 |
| LMF2 | -6316 |
| ANKH | -6326 |
| PSMB5 | -6339 |
| ATP9B | -6391 |
| PSMD4 | -6409 |
| AQP7 | -6447 |
| ATP8A1 | -6450 |
| PSMD9 | -6463 |
| AQP2 | -6470 |
| ATP6V0D1 | -6478 |
| ANO10 | -6543 |
| SLC2A14 | -6566 |
| GNB4 | -6570 |
| LETM1 | -6573 |
| ATP1A2 | -6604 |
| PSMD3 | -6608 |
| SLC22A1 | -6619 |
| NCEH1 | -6658 |
| AQP9 | -6689 |
| TRPC4AP | -6697 |
| ATP6V1C1 | -6746 |
| NIPA2 | -6747 |
| RAB11A | -6808 |
| SLC32A1 | -6820 |
| SLC12A7 | -6892 |
| SLC7A11 | -7045 |
| SLC7A1 | -7130 |
| SLC12A4 | -7271 |
| SRI | -7351 |
| PSMD13 | -7362 |
| SLC6A9 | -7380 |
| PRKAR1B | -7460 |
| SLC16A1 | -7566 |
| ATP11A | -7572 |
| MICU2 | -7575 |
| SLC1A4 | -7598 |
| SLC26A11 | -7672 |
| SLC17A3 | -7689 |
| ATP6V1G3 | -7728 |
| PRKACB | -7806 |
| STEAP2 | -7838 |
| PSMC1 | -7848 |
| RAB11FIP2 | -7873 |
| LCAT | -7916 |
| SLC36A2 | -7951 |
| LPL | -7972 |
| PEX19 | -8045 |
| SLC39A6 | -8116 |
| TUSC3 | -8134 |
| SLC6A15 | -8139 |
| SLC16A8 | -8172 |
| TRPC6 | -8219 |
| ATP6V1H | -8321 |
| SLC27A6 | -8413 |
| SLC2A8 | -8470 |
| NIPA1 | -8483 |
| APOA2 | -8511 |
| PSMB11 | -8512 |
| APOF | -8539 |
| PLN | -8570 |
| SLC12A5 | -8572 |
| LRRC8B | -8634 |
| APOB | -8669 |
| EIF2S2 | -8715 |
| ATP13A1 | -8780 |
| LCN1 | -8850 |
| PSMD2 | -8887 |
| SLC22A17 | -8913 |
| LRRC8C | -8924 |
| SLC2A2 | -8932 |
| SLC25A4 | -8941 |
| ATP2A2 | -8978 |
| NIPAL3 | -8986 |
| TRPV5 | -9047 |
| HBA2 | -9089 |
| ATP6V0E2 | -9165 |
| IREB2 | -9307 |
| RSC1A1 | -9327 |
| HFE | -9357 |
| PARL | -9399 |
| CLCNKA | -9403 |
| RIPK1 | -9477 |
| HBA1 | -9509 |
| PRKACG | -9541 |
| TRPV2 | -9581 |
| GNAS | -9712 |
| SLC15A2 | -9821 |
REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY
| 533 | |
|---|---|
| set | REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY |
| setSize | 74 |
| pANOVA | 0.000195 |
| s.dist | -0.25 |
| p.adjustANOVA | 0.0133 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| VRK1 | -9290 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| TUBA3E | -8293 |
| POM121 | -8267 |
| CHMP4C | -7757 |
| CHMP4B | -7159 |
| SPAST | -7098 |
| CCNB2 | -6945 |
| ANKLE2 | -6706 |
| TUBA4A | -6626 |
| TUBB2B | -6314 |
| TUBB2A | -5979 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CC2D1B | -9830 |
| CHMP2B | -9643 |
| VRK1 | -9290 |
| CHMP4A | -9177 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| LEMD2 | -8856 |
| VPS4A | -8736 |
| TUBA1C | -8675 |
| TUBA3E | -8293 |
| POM121 | -8267 |
| CHMP4C | -7757 |
| CHMP4B | -7159 |
| SPAST | -7098 |
| CCNB2 | -6945 |
| ANKLE2 | -6706 |
| TUBA4A | -6626 |
| TUBB2B | -6314 |
| TUBB2A | -5979 |
| LMNB1 | -5639 |
| SIRT2 | -5451 |
| CHMP2A | -5098 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CHMP3 | -4842 |
| TUBA1B | -4624 |
| NUP107 | -4561 |
| NUP85 | -4358 |
| NUP98 | -4330 |
| PPP2R2A | -4274 |
| TUBA8 | -4032 |
| NUP43 | -3906 |
| NUP35 | -3876 |
| NUP133 | -3446 |
| NUP188 | -2837 |
| LEMD3 | -2627 |
| RANGAP1 | -2606 |
| NUP205 | -2593 |
| CDK1 | -2219 |
| RAN | -2031 |
| TUBA1A | -1819 |
| TMPO | -1743 |
| CHMP7 | -1636 |
| LBR | -1592 |
| KPNB1 | -1539 |
| TNPO1 | -607 |
| NUP160 | -518 |
| AHCTF1 | -75 |
| IST1 | 123 |
| NUP37 | 339 |
| VRK2 | 465 |
| BANF1 | 835 |
| SEC13 | 959 |
| TUBB1 | 1069 |
| RCC1 | 1490 |
| NUP62 | 1710 |
| SUMO1 | 2052 |
| NUP93 | 2760 |
| NDC1 | 2860 |
| TUBA3C | 3214 |
| TUBB6 | 3539 |
| TUBB4A | 3612 |
| NUP54 | 4170 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| LMNA | 5119 |
| NUP58 | 5365 |
| SEH1L | 5647 |
| TUBB3 | 6221 |
| UBE2I | 7189 |
| CHMP6 | 7265 |
| NUP155 | 7411 |
| TUBB8 | 11325 |
REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE
| 289 | |
|---|---|
| set | REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE |
| setSize | 277 |
| pANOVA | 0.000218 |
| s.dist | -0.129 |
| p.adjustANOVA | 0.0143 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CYCS | -9162 |
| TUBB4B | -9023 |
| DYNLT5 | -8928 |
| DYNC2I1 | -8711 |
| TUBA1C | -8675 |
| WDR19 | -8590 |
| MICOS10 | -8465 |
| PKD2 | -8449 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| GBF1 | -8249 |
| PPARA | -8024 |
| IFT22 | -7821 |
| CEP164 | -7722 |
| SSBP1 | -7715 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| NCOA6 | -7292 |
| TTC21B | -7178 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| CYCS | -9162 |
| TUBB4B | -9023 |
| DYNLT5 | -8928 |
| DYNC2I1 | -8711 |
| TUBA1C | -8675 |
| WDR19 | -8590 |
| MICOS10 | -8465 |
| PKD2 | -8449 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| GBF1 | -8249 |
| PPARA | -8024 |
| IFT22 | -7821 |
| CEP164 | -7722 |
| SSBP1 | -7715 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| NCOA6 | -7292 |
| TTC21B | -7178 |
| BBS2 | -7084 |
| ODF2 | -7061 |
| ATP5PF | -6873 |
| NCOA1 | -6850 |
| NPHP4 | -6826 |
| RAB11A | -6808 |
| PLK1 | -6633 |
| MTX2 | -6632 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| BBIP1 | -6542 |
| TWNK | -6540 |
| MED1 | -6514 |
| BBS10 | -6497 |
| PCM1 | -6483 |
| NR1D1 | -6475 |
| TFB1M | -6471 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| EXOC3 | -6324 |
| GABPA | -6322 |
| TUBB2B | -6314 |
| CEP72 | -6174 |
| HAUS5 | -6025 |
| TUBB2A | -5979 |
| ATP5MC1 | -5880 |
| DYNLRB1 | -5780 |
| PDE6D | -5747 |
| TMEM11 | -5684 |
| TRAF3IP1 | -5636 |
| PKD1 | -5568 |
| MARK4 | -5432 |
| CRTC3 | -5423 |
| CLASP1 | -5346 |
| MKKS | -5255 |
| TTC8 | -5253 |
| ATP5F1B | -5252 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| HELZ2 | -5011 |
| CEP43 | -4973 |
| DYNLRB2 | -4945 |
| CCT2 | -4861 |
| EXOC4 | -4853 |
| SDCCAG8 | -4735 |
| POLRMT | -4719 |
| BBS12 | -4710 |
| TUBA1B | -4624 |
| SCLT1 | -4621 |
| PCNT | -4617 |
| WDR35 | -4591 |
| DYNC2LI1 | -4578 |
| CEP250 | -4503 |
| KIF24 | -4463 |
| INPP5E | -4454 |
| TCP1 | -4377 |
| NRF1 | -4366 |
| SIRT5 | -4191 |
| CEP41 | -4178 |
| DNAJC11 | -4159 |
| CEP162 | -4131 |
| TRIP11 | -4089 |
| NCOA2 | -4049 |
| TUBA8 | -4032 |
| C2CD3 | -4007 |
| TTBK2 | -3924 |
| CAMK4 | -3886 |
| RAB11FIP3 | -3798 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| ARL6 | -3709 |
| CLUAP1 | -3678 |
| CHCHD3 | -3628 |
| ATP5F1C | -3586 |
| CEP89 | -3583 |
| EXOC7 | -3567 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| IMMT | -3443 |
| EXOC2 | -3292 |
| CREBBP | -3271 |
| HSPA9 | -3249 |
| AKAP9 | -3238 |
| ATF2 | -3228 |
| ATP5PO | -3010 |
| AHI1 | -2990 |
| MAPK14 | -2900 |
| PRKAG2 | -2796 |
| CEP70 | -2717 |
| TGS1 | -2634 |
| B9D2 | -2628 |
| PAFAH1B1 | -2571 |
| PERM1 | -2569 |
| RPGRIP1L | -2559 |
| PPRC1 | -2418 |
| CALM1 | -2398 |
| CDK1 | -2219 |
| ATP5MF | -2202 |
| PRKAB2 | -2119 |
| HAUS6 | -2029 |
| CEP290 | -2002 |
| IFT46 | -1978 |
| ARF4 | -1971 |
| SOD2 | -1874 |
| HDAC3 | -1872 |
| TUBA1A | -1819 |
| ATP5MC2 | -1702 |
| CDK5RAP2 | -1570 |
| POLG2 | -1559 |
| CCP110 | -1489 |
| ATP5F1D | -1485 |
| ATAT1 | -1243 |
| NCOR1 | -1234 |
| IFT57 | -1200 |
| NPHP3 | -1171 |
| CEP83 | -1166 |
| IQCB1 | -1155 |
| KIFAP3 | -1087 |
| ASAP1 | -1056 |
| TFB2M | -994 |
| PRKAA2 | -988 |
| CARM1 | -800 |
| PPARGC1A | -698 |
| USP46 | -675 |
| TNPO1 | -607 |
| BBS4 | -564 |
| YWHAE | -521 |
| CHCHD6 | -370 |
| DCTN1 | -338 |
| DMAC2L | -216 |
| NEK2 | -182 |
| CC2D2A | -72 |
| CEP78 | 13 |
| YWHAG | 115 |
| TUBB | 261 |
| IFT140 | 326 |
| TCTN1 | 382 |
| CREB1 | 391 |
| KIF3C | 440 |
| TCTN2 | 482 |
| ATP5F1E | 484 |
| KIF3B | 591 |
| DYNC2H1 | 665 |
| TFAM | 705 |
| NEDD1 | 779 |
| FBF1 | 808 |
| RAB3IP | 819 |
| IFT80 | 859 |
| CCT4 | 935 |
| HAUS3 | 961 |
| CENPJ | 1016 |
| TMEM67 | 1049 |
| EXOC8 | 1059 |
| TUBB1 | 1069 |
| BBS5 | 1110 |
| ATP5PD | 1231 |
| CSNK1E | 1281 |
| SIRT3 | 1331 |
| SMARCD3 | 1464 |
| CSNK1D | 1496 |
| NPHP1 | 1576 |
| MAPK11 | 1621 |
| DYNLT2 | 1652 |
| DYNC2I2 | 1671 |
| CYS1 | 1827 |
| RHO | 1851 |
| ATP5MC3 | 1949 |
| IFT20 | 1957 |
| CCT8 | 2014 |
| MEF2C | 2082 |
| SSNA1 | 2103 |
| IFT27 | 2141 |
| TBL1XR1 | 2184 |
| ACTR1A | 2220 |
| CHD9 | 2242 |
| SFI1 | 2352 |
| EXOC6 | 2353 |
| CRTC1 | 2400 |
| SSTR3 | 2424 |
| KIF3A | 2489 |
| MAPRE1 | 2575 |
| CCT5 | 2602 |
| IFT74 | 2677 |
| ARL3 | 2700 |
| IDH2 | 2717 |
| ALMS1 | 2804 |
| SAMM50 | 2869 |
| SMO | 2979 |
| EXOC5 | 3012 |
| RAB8A | 3057 |
| IFT122 | 3162 |
| BBS7 | 3198 |
| TUBA3C | 3214 |
| LZTFL1 | 3370 |
| TUBB6 | 3539 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| GLUD1 | 3602 |
| TUBB4A | 3612 |
| CRTC2 | 3642 |
| GABPB1 | 3655 |
| CCT3 | 3701 |
| RXRA | 3719 |
| B9D1 | 3770 |
| KIF17 | 3923 |
| EXOC1 | 4023 |
| MTX1 | 4048 |
| PRKAR2B | 4071 |
| ACSS2 | 4137 |
| ATP5PB | 4219 |
| IFT88 | 4264 |
| PRKAG3 | 4377 |
| HSP90AA1 | 4414 |
| BBS9 | 4424 |
| PPP2R1A | 4431 |
| ATP5ME | 4450 |
| PRKAB1 | 4466 |
| IFT52 | 4480 |
| HAUS2 | 4581 |
| MICOS13 | 4588 |
| BBS1 | 4767 |
| ARL13B | 4789 |
| HAUS4 | 4825 |
| CEP97 | 4897 |
| ATP5MG | 4952 |
| ALAS1 | 5124 |
| DYNLT2B | 5242 |
| ESRRA | 5247 |
| HAUS1 | 5311 |
| MTERF1 | 5587 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| PRKAG1 | 5864 |
| IFT43 | 5933 |
| PRKACA | 6168 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| IFT81 | 6460 |
| CNGB1 | 6587 |
| ATP5F1A | 6593 |
| SIRT4 | 6710 |
| MKS1 | 7244 |
| IFT172 | 7527 |
| TMEM216 | 7587 |
| PPARGC1B | 7709 |
| UNC119B | 8490 |
| MCHR1 | 9187 |
| NINL | 9656 |
| TCTN3 | 9802 |
| MAPK12 | 10217 |
| MEF2D | 10847 |
| CNGA4 | 10986 |
| TUBB8 | 11325 |
REACTOME_CELLULAR_SENESCENCE
| 503 | |
|---|---|
| set | REACTOME_CELLULAR_SENESCENCE |
| setSize | 189 |
| pANOVA | 0.000293 |
| s.dist | -0.153 |
| p.adjustANOVA | 0.0185 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H1-5 | -9805.0 |
| ETS2 | -9684.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| PHC1 | -9332.0 |
| UBN1 | -9294.0 |
| H1-3 | -9268.0 |
| H3C4 | -9267.0 |
| TFDP1 | -9109.0 |
| H1-0 | -8905.0 |
| RB1 | -8714.0 |
| SUZ12 | -8683.0 |
| ANAPC5 | -8661.0 |
| H1-1 | -8637.0 |
| H4C13 | -8603.0 |
| MIR24-1 | -8393.0 |
| TXN | -8297.0 |
| H2BC13 | -8199.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H1-5 | -9805.0 |
| ETS2 | -9684.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| PHC1 | -9332.0 |
| UBN1 | -9294.0 |
| H1-3 | -9268.0 |
| H3C4 | -9267.0 |
| TFDP1 | -9109.0 |
| H1-0 | -8905.0 |
| RB1 | -8714.0 |
| SUZ12 | -8683.0 |
| ANAPC5 | -8661.0 |
| H1-1 | -8637.0 |
| H4C13 | -8603.0 |
| MIR24-1 | -8393.0 |
| TXN | -8297.0 |
| H2BC13 | -8199.0 |
| IL6 | -8175.0 |
| MAPK9 | -8174.0 |
| TERF1 | -8123.0 |
| H4C16 | -8109.0 |
| MAPKAPK5 | -7833.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| H2AX | -7648.0 |
| H3C6 | -7372.0 |
| EP400 | -7235.0 |
| CDKN1B | -6954.0 |
| CBX8 | -6701.0 |
| H2BC10 | -6510.0 |
| MOV10 | -6196.0 |
| EHMT2 | -6169.0 |
| VENTX | -6123.0 |
| TINF2 | -6121.0 |
| ID1 | -5961.0 |
| ANAPC7 | -5789.0 |
| H2AC6 | -5775.0 |
| CBX4 | -5719.0 |
| H2BC15 | -5694.0 |
| EHMT1 | -5643.0 |
| LMNB1 | -5639.0 |
| H3C11 | -5538.0 |
| FOS | -5453.0 |
| H3-4 | -5447.0 |
| CBX6 | -5319.0 |
| MAP2K6 | -5315.0 |
| H2BC6 | -5295.0 |
| ATM | -5218.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| E2F2 | -5059.0 |
| CABIN1 | -4929.0 |
| CDC23 | -4806.0 |
| TFDP2 | -4787.0 |
| CDC27 | -4761.0 |
| CDKN2A | -4700.0 |
| TNRC6C | -4643.0 |
| EED | -4626.0 |
| SP1 | -4623.0 |
| H4C6 | -4534.0 |
| UBE2D1 | -4355.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| H2BC17 | -4192.0 |
| TNIK | -4166.0 |
| UBE2E1 | -4108.0 |
| PHC2 | -4060.0 |
| TNRC6A | -4043.0 |
| RAD50 | -4035.0 |
| H4C4 | -3867.0 |
| BMI1 | -3827.0 |
| H2AJ | -3814.0 |
| ANAPC2 | -3617.0 |
| TERF2IP | -3592.0 |
| H2BC26 | -3582.0 |
| MAP4K4 | -3301.0 |
| ANAPC15 | -3203.0 |
| CDKN1A | -3164.0 |
| MAP2K4 | -3031.0 |
| RING1 | -2953.0 |
| MAPK14 | -2900.0 |
| NFKB1 | -2707.0 |
| MAPKAPK2 | -2687.0 |
| E2F3 | -2555.0 |
| ASF1A | -2533.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| MAP2K7 | -2474.0 |
| HMGA2 | -2404.0 |
| AGO4 | -2358.0 |
| CDK6 | -2302.0 |
| KDM6B | -2147.0 |
| TNRC6B | -2096.0 |
| KAT5 | -1955.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| H2AC8 | -1573.0 |
| SCMH1 | -1534.0 |
| RPS6KA2 | -1273.0 |
| AGO3 | -1258.0 |
| MAPK7 | -1222.0 |
| MAPKAPK3 | -1139.0 |
| EZH2 | -1086.0 |
| CDKN2C | -1068.0 |
| H2BC8 | -1029.0 |
| ANAPC11 | -1014.0 |
| RNF2 | -892.0 |
| TP53 | -548.0 |
| H2AZ2 | -340.0 |
| UBA52 | -167.0 |
| H3-3B | -135.0 |
| H1-2 | -81.0 |
| MAPK1 | 78.0 |
| MAP3K5 | 109.0 |
| MDM4 | 110.0 |
| HIRA | 126.0 |
| IFNB1 | 190.0 |
| MAPK8 | 364.0 |
| ERF | 544.0 |
| POT1 | 546.0 |
| H4C5 | 878.0 |
| CDC16 | 1047.0 |
| FZR1 | 1228.0 |
| PHC3 | 1319.0 |
| ETS1 | 1451.0 |
| H1-4 | 1492.0 |
| MAPK11 | 1621.0 |
| CEBPB | 1814.0 |
| RPS27A | 1846.0 |
| TERF2 | 1872.0 |
| H2BC3 | 1920.0 |
| RPS6KA1 | 2135.0 |
| CBX2 | 2171.0 |
| JUN | 2245.0 |
| HMGA1 | 2278.0 |
| IGFBP7 | 2406.0 |
| MAPK3 | 2444.0 |
| H2BC1 | 2755.0 |
| E2F1 | 2922.0 |
| RELA | 3308.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| NBN | 3478.0 |
| CDC26 | 3611.0 |
| H3C2 | 3915.0 |
| CCNE2 | 4280.0 |
| H3-3A | 4335.0 |
| ACD | 4346.5 |
| CCNA2 | 4366.0 |
| RBBP4 | 4375.0 |
| CDK4 | 4604.0 |
| H4C3 | 5053.0 |
| MINK1 | 5131.0 |
| CDK2 | 5165.0 |
| UBE2S | 5479.0 |
| MRE11 | 5531.0 |
| MDM2 | 5757.0 |
| H3C3 | 5902.0 |
| H3C1 | 6001.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| UBC | 6700.0 |
| H2AC4 | 6905.0 |
| AGO1 | 7256.0 |
| MAPK10 | 7289.0 |
| H2BC21 | 7408.0 |
| CCNE1 | 7482.0 |
| CDKN2B | 7557.0 |
| UBB | 7594.0 |
| MAP2K3 | 7631.0 |
| H2BC12 | 7676.0 |
| STAT3 | 7887.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| CXCL8 | 8674.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| H2AZ1 | 8917.0 |
| H2AC14 | 9376.0 |
| CDKN2D | 9489.0 |
| H4C9 | 9492.0 |
| H4C12 | 10027.0 |
| ANAPC1 | 10085.0 |
| MIR24-2 | 10120.0 |
| H2BC14 | 10168.0 |
| IL1A | 10585.0 |
REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF
| 200 | |
|---|---|
| set | REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF |
| setSize | 53 |
| pANOVA | 0.000348 |
| s.dist | -0.284 |
| p.adjustANOVA | 0.0212 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACACB | -9045 |
| FASN | -8998 |
| FDPS | -8743 |
| SEC24C | -8660 |
| GPAM | -8535 |
| HMGCR | -8075 |
| PPARA | -8024 |
| SEC24B | -7747 |
| SCAP | -7564 |
| NCOA6 | -7292 |
| NCOA1 | -6850 |
| SEC23A | -6518 |
| MED1 | -6514 |
| NFYA | -6252 |
| IDI1 | -5711 |
| PMVK | -5688 |
| TM7SF2 | -5204 |
| HELZ2 | -5011 |
| HMGCS1 | -4852 |
| SP1 | -4623 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACACB | -9045 |
| FASN | -8998 |
| FDPS | -8743 |
| SEC24C | -8660 |
| GPAM | -8535 |
| HMGCR | -8075 |
| PPARA | -8024 |
| SEC24B | -7747 |
| SCAP | -7564 |
| NCOA6 | -7292 |
| NCOA1 | -6850 |
| SEC23A | -6518 |
| MED1 | -6514 |
| NFYA | -6252 |
| IDI1 | -5711 |
| PMVK | -5688 |
| TM7SF2 | -5204 |
| HELZ2 | -5011 |
| HMGCS1 | -4852 |
| SP1 | -4623 |
| SEC24D | -4414 |
| NCOA2 | -4049 |
| SREBF1 | -3956 |
| SEC24A | -3490 |
| CREBBP | -3271 |
| ELOVL6 | -3056 |
| NFYC | -2954 |
| FDFT1 | -2675 |
| TGS1 | -2634 |
| SQLE | -2104 |
| RAN | -2031 |
| INSIG1 | -1924 |
| SC5D | -1600 |
| KPNB1 | -1539 |
| SREBF2 | -1040 |
| CARM1 | -800 |
| SCD | -297 |
| MVK | -131 |
| MBTPS1 | -25 |
| ACACA | 3 |
| NFYB | 8 |
| SMARCD3 | 1464 |
| LSS | 1664 |
| GGPS1 | 1875 |
| TBL1XR1 | 2184 |
| CHD9 | 2242 |
| RXRA | 3719 |
| DHCR7 | 3872 |
| MVD | 4411 |
| INSIG2 | 4814 |
| MTF1 | 5123 |
| CYP51A1 | 5789 |
| SAR1B | 8361 |
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS
| 492 | |
|---|---|
| set | REACTOME_SEPARATION_OF_SISTER_CHROMATIDS |
| setSize | 184 |
| pANOVA | 0.000362 |
| s.dist | -0.152 |
| p.adjustANOVA | 0.0212 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| UBE2C | -9474 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBB4B | -9023 |
| SGO2 | -8909 |
| PSMD2 | -8887 |
| TUBA1C | -8675 |
| ANAPC5 | -8661 |
| CENPH | -8616 |
| PSMB11 | -8512 |
| TUBA3E | -8293 |
| NDEL1 | -8074 |
| PSMC1 | -7848 |
| ANAPC4 | -7831 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| PSMD13 | -7362 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| UBE2C | -9474 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBB4B | -9023 |
| SGO2 | -8909 |
| PSMD2 | -8887 |
| TUBA1C | -8675 |
| ANAPC5 | -8661 |
| CENPH | -8616 |
| PSMB11 | -8512 |
| TUBA3E | -8293 |
| NDEL1 | -8074 |
| PSMC1 | -7848 |
| ANAPC4 | -7831 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| PSMD13 | -7362 |
| KIF2C | -7337 |
| PTTG1 | -7163 |
| CENPC | -6867 |
| PLK1 | -6633 |
| PPP1CC | -6627 |
| TUBA4A | -6626 |
| PSMD3 | -6608 |
| DYNC1H1 | -6464 |
| PSMD9 | -6463 |
| PSMD4 | -6409 |
| PSMB5 | -6339 |
| TUBB2B | -6314 |
| CENPF | -6110 |
| ZW10 | -6072 |
| MAD2L1 | -6059 |
| PSMD11 | -6044 |
| PSMC2 | -6032 |
| TUBB2A | -5979 |
| ESPL1 | -5959 |
| ANAPC7 | -5789 |
| CLIP1 | -5755 |
| CLASP1 | -5346 |
| PSMC3 | -5262 |
| PPP2R5E | -5142 |
| DYNC1I2 | -5131 |
| PSME4 | -5053 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| PSMA5 | -4888 |
| CDC23 | -4806 |
| CDC27 | -4761 |
| DYNC1LI2 | -4730 |
| PSMD5 | -4711 |
| KIF2A | -4638 |
| TUBA1B | -4624 |
| NUP107 | -4561 |
| NUP85 | -4358 |
| UBE2D1 | -4355 |
| XPO1 | -4345 |
| CLASP2 | -4343 |
| NUP98 | -4330 |
| PSMB6 | -4271 |
| UBE2E1 | -4108 |
| TUBA8 | -4032 |
| PSMD1 | -3979 |
| WAPL | -3947 |
| NUP43 | -3906 |
| CENPA | -3845 |
| KNTC1 | -3683 |
| ANAPC2 | -3617 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| NUF2 | -3541 |
| NUP133 | -3446 |
| SPDL1 | -3370 |
| MAD1L1 | -3364 |
| ANAPC15 | -3203 |
| PSMC4 | -3089 |
| RAD21 | -3080 |
| ZWILCH | -3078 |
| RCC2 | -2861 |
| PSMB1 | -2799 |
| ITGB3BP | -2777 |
| CENPQ | -2767 |
| B9D2 | -2628 |
| RANGAP1 | -2606 |
| PAFAH1B1 | -2571 |
| PSMA2 | -2485 |
| BIRC5 | -2354 |
| PSMC6 | -2126 |
| DYNC1I1 | -2088 |
| CENPT | -2076 |
| PDS5B | -2067 |
| TUBA1A | -1819 |
| ANAPC16 | -1795 |
| PSMB9 | -1684 |
| PSMA3 | -1391 |
| PSME3 | -1153 |
| SGO1 | -1080 |
| PDS5A | -1046 |
| ANAPC11 | -1014 |
| CDCA8 | -916 |
| CENPP | -551 |
| NUP160 | -518 |
| PSMA1 | -477 |
| DSN1 | -331 |
| PSMB8 | -260 |
| UBA52 | -167 |
| STAG1 | -147 |
| AHCTF1 | -75 |
| KIF2B | -57 |
| SKA2 | 265 |
| NUP37 | 339 |
| BUB1B | 349 |
| PSMB10 | 447 |
| BUB1 | 660 |
| NSL1 | 804 |
| CENPS | 874 |
| PSMD12 | 901 |
| SEC13 | 959 |
| KIF18A | 960 |
| CDC16 | 1047 |
| TUBB1 | 1069 |
| SMC3 | 1172 |
| PSMD14 | 1213 |
| CENPM | 1294 |
| SPC25 | 1348 |
| PPP2R5A | 1480 |
| SEM1 | 1794 |
| RPS27A | 1846 |
| CENPN | 1892 |
| MIS12 | 1902 |
| PSMC5 | 2183 |
| PSMD8 | 2235 |
| CENPE | 2236 |
| PPP2R5C | 2434 |
| MAPRE1 | 2575 |
| RANBP2 | 3016 |
| TUBA3C | 3214 |
| SKA1 | 3245 |
| PPP2CB | 3417 |
| NUDC | 3440 |
| CENPK | 3476 |
| CENPL | 3515 |
| TUBB6 | 3539 |
| CDC26 | 3611 |
| TUBB4A | 3612 |
| PPP2R5B | 4232 |
| PMF1 | 4398 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| CDCA5 | 4721 |
| AURKB | 4877 |
| PSMB4 | 4971 |
| SPC24 | 5022 |
| PSMF1 | 5221 |
| PSMD7 | 5305 |
| TAOK1 | 5424 |
| UBE2S | 5479 |
| SEH1L | 5647 |
| RPS27 | 5679 |
| PSMB2 | 5803 |
| PSMB7 | 5858 |
| NDC80 | 6086 |
| TUBB3 | 6221 |
| ANAPC10 | 6467 |
| PSMA8 | 6502 |
| KNL1 | 6545 |
| PSMD6 | 6616 |
| PSME2 | 6638 |
| UBC | 6700 |
| PPP2R5D | 6733 |
| DYNC1LI1 | 6830 |
| CENPU | 6916 |
| PSMA6 | 6984 |
| CDC20 | 7234 |
| PSMA4 | 7568 |
| UBB | 7594 |
| BUB3 | 7623 |
| PSMB3 | 8017 |
| PSMA7 | 9563 |
| PSME1 | 9765 |
| ANAPC1 | 10085 |
| TUBB8 | 11325 |
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION
| 496 | |
|---|---|
| set | REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION |
| setSize | 120 |
| pANOVA | 0.000465 |
| s.dist | -0.185 |
| p.adjustANOVA | 0.0263 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| TUBA1C | -8675 |
| CENPH | -8616 |
| TUBA3E | -8293 |
| NDEL1 | -8074 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| KIF2C | -7337 |
| CCNB2 | -6945 |
| CENPC | -6867 |
| PLK1 | -6633 |
| PPP1CC | -6627 |
| TUBA4A | -6626 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| INCENP | -9447 |
| PPP2R1B | -9252 |
| TUBB4B | -9023 |
| CCNB1 | -8935 |
| SGO2 | -8909 |
| TUBA1C | -8675 |
| CENPH | -8616 |
| TUBA3E | -8293 |
| NDEL1 | -8074 |
| CENPO | -7707 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| ZWINT | -7442 |
| KIF2C | -7337 |
| CCNB2 | -6945 |
| CENPC | -6867 |
| PLK1 | -6633 |
| PPP1CC | -6627 |
| TUBA4A | -6626 |
| DYNC1H1 | -6464 |
| TUBB2B | -6314 |
| CENPF | -6110 |
| ZW10 | -6072 |
| MAD2L1 | -6059 |
| TUBB2A | -5979 |
| CLIP1 | -5755 |
| CLASP1 | -5346 |
| PPP2R5E | -5142 |
| DYNC1I2 | -5131 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| DYNC1LI2 | -4730 |
| KIF2A | -4638 |
| TUBA1B | -4624 |
| NUP107 | -4561 |
| NUP85 | -4358 |
| XPO1 | -4345 |
| CLASP2 | -4343 |
| NUP98 | -4330 |
| TUBA8 | -4032 |
| WAPL | -3947 |
| NUP43 | -3906 |
| CENPA | -3845 |
| KNTC1 | -3683 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| NUF2 | -3541 |
| NUP133 | -3446 |
| SPDL1 | -3370 |
| MAD1L1 | -3364 |
| RAD21 | -3080 |
| ZWILCH | -3078 |
| RCC2 | -2861 |
| ITGB3BP | -2777 |
| CENPQ | -2767 |
| B9D2 | -2628 |
| RANGAP1 | -2606 |
| PAFAH1B1 | -2571 |
| BIRC5 | -2354 |
| CDK1 | -2219 |
| DYNC1I1 | -2088 |
| CENPT | -2076 |
| PDS5B | -2067 |
| TUBA1A | -1819 |
| SGO1 | -1080 |
| PDS5A | -1046 |
| CDCA8 | -916 |
| CENPP | -551 |
| NUP160 | -518 |
| DSN1 | -331 |
| STAG1 | -147 |
| AHCTF1 | -75 |
| KIF2B | -57 |
| SKA2 | 265 |
| NUP37 | 339 |
| BUB1B | 349 |
| BUB1 | 660 |
| NSL1 | 804 |
| CENPS | 874 |
| SEC13 | 959 |
| KIF18A | 960 |
| TUBB1 | 1069 |
| SMC3 | 1172 |
| CENPM | 1294 |
| SPC25 | 1348 |
| PPP2R5A | 1480 |
| CENPN | 1892 |
| MIS12 | 1902 |
| CENPE | 2236 |
| PPP2R5C | 2434 |
| MAPRE1 | 2575 |
| RANBP2 | 3016 |
| TUBA3C | 3214 |
| SKA1 | 3245 |
| PPP2CB | 3417 |
| NUDC | 3440 |
| CENPK | 3476 |
| CENPL | 3515 |
| TUBB6 | 3539 |
| TUBB4A | 3612 |
| PPP2R5B | 4232 |
| PMF1 | 4398 |
| PPP2CA | 4421 |
| PPP2R1A | 4431 |
| CDCA5 | 4721 |
| AURKB | 4877 |
| SPC24 | 5022 |
| TAOK1 | 5424 |
| SEH1L | 5647 |
| RPS27 | 5679 |
| NDC80 | 6086 |
| TUBB3 | 6221 |
| KNL1 | 6545 |
| PPP2R5D | 6733 |
| DYNC1LI1 | 6830 |
| CENPU | 6916 |
| CDC20 | 7234 |
| BUB3 | 7623 |
| TUBB8 | 11325 |
REACTOME_ANTIMICROBIAL_PEPTIDES
| 1060 | |
|---|---|
| set | REACTOME_ANTIMICROBIAL_PEPTIDES |
| setSize | 76 |
| pANOVA | 0.000519 |
| s.dist | 0.23 |
| p.adjustANOVA | 0.0284 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LCN2 | 11357 |
| HTN1 | 11296 |
| RNASE3 | 11099 |
| RNASE7 | 11071 |
| DEFB124 | 11070 |
| EPPIN-WFDC6 | 11005 |
| PGLYRP4 | 10832 |
| S100A9 | 10608 |
| BPIFB6 | 10475 |
| BPIFB2 | 10403 |
| CAMP | 10385 |
| S100A8 | 10373 |
| BPIFB4 | 10323 |
| PI3 | 10310 |
| S100A7 | 10245 |
| PGLYRP3 | 10175 |
| DCD | 10165 |
| RNASE8 | 9976 |
| CCR2 | 9871 |
| DEFA5 | 9729 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LCN2 | 11357.0 |
| HTN1 | 11296.0 |
| RNASE3 | 11099.0 |
| RNASE7 | 11071.0 |
| DEFB124 | 11070.0 |
| EPPIN-WFDC6 | 11005.0 |
| PGLYRP4 | 10832.0 |
| S100A9 | 10608.0 |
| BPIFB6 | 10475.0 |
| BPIFB2 | 10403.0 |
| CAMP | 10385.0 |
| S100A8 | 10373.0 |
| BPIFB4 | 10323.0 |
| PI3 | 10310.0 |
| S100A7 | 10245.0 |
| PGLYRP3 | 10175.0 |
| DCD | 10165.0 |
| RNASE8 | 9976.0 |
| CCR2 | 9871.0 |
| DEFA5 | 9729.0 |
| ART1 | 9527.0 |
| REG3A | 9130.0 |
| DEFB133 | 9095.0 |
| BPIFB1 | 8908.0 |
| PRTN3 | 8821.0 |
| DEFB134 | 8693.0 |
| DEFB135 | 8530.0 |
| DEFB104A | 8394.5 |
| DEFB104B | 8394.5 |
| SLC11A1 | 8130.0 |
| TLR1 | 7534.0 |
| EPPIN | 7458.0 |
| BPIFA1 | 7394.0 |
| CTSG | 6355.0 |
| PLA2G2A | 6306.0 |
| HTN3 | 6047.0 |
| SEMG1 | 5898.0 |
| CCR6 | 5675.0 |
| DEFB132 | 5164.0 |
| PGLYRP2 | 5092.0 |
| ATOX1 | 4809.0 |
| DEFB136 | 3212.0 |
| DEFB113 | 1796.0 |
| DEFB123 | 1193.0 |
| DEFB127 | 1045.0 |
| CLU | 998.0 |
| LTF | 962.0 |
| DEFA4 | 554.0 |
| TLR2 | -76.0 |
| ITLN1 | -194.0 |
| CD4 | -696.0 |
| CHGA | -1467.0 |
| PRSS3 | -1490.0 |
| PGLYRP1 | -1945.0 |
| DEFB114 | -2012.0 |
| GNLY | -2460.0 |
| DEFB121 | -2511.0 |
| DEFB1 | -3690.0 |
| BPI | -3904.0 |
| BPIFA2 | -3961.0 |
| DEFB119 | -4819.0 |
| DEFA6 | -4999.0 |
| RNASE6 | -5415.0 |
| DEFB118 | -5426.0 |
| DEFB129 | -5878.0 |
| S100A7A | -6898.0 |
| DEFB110 | -7101.0 |
| DEFB126 | -7420.0 |
| ELANE | -7880.0 |
| LEAP2 | -7975.0 |
| DEFB116 | -8301.0 |
| DEFB115 | -8774.0 |
| REG3G | -8942.0 |
| LYZ | -9090.0 |
| DEFB128 | -9281.0 |
| DEFB125 | -10071.0 |
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
| 615 | |
|---|---|
| set | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES |
| setSize | 55 |
| pANOVA | 0.000549 |
| s.dist | 0.269 |
| p.adjustANOVA | 0.0289 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL1 | 11360 |
| PPBP | 11350 |
| CCL4 | 11339 |
| CCL11 | 11320 |
| CXCR5 | 11212 |
| CCL3 | 11173 |
| CXCR1 | 11124 |
| CCL16 | 10983 |
| ACKR2 | 10882 |
| CCL13 | 10670 |
| CCR7 | 10612 |
| CCL19 | 10278 |
| CX3CR1 | 10142 |
| CCR2 | 9871 |
| CCL2 | 9673 |
| CXCR6 | 9514 |
| CCL25 | 9393 |
| CXCL12 | 9321 |
| CCR5 | 9293 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL1 | 11360 |
| PPBP | 11350 |
| CCL4 | 11339 |
| CCL11 | 11320 |
| CXCR5 | 11212 |
| CCL3 | 11173 |
| CXCR1 | 11124 |
| CCL16 | 10983 |
| ACKR2 | 10882 |
| CCL13 | 10670 |
| CCR7 | 10612 |
| CCL19 | 10278 |
| CX3CR1 | 10142 |
| CCR2 | 9871 |
| CCL2 | 9673 |
| CXCR6 | 9514 |
| CCL25 | 9393 |
| CXCL12 | 9321 |
| CCR5 | 9293 |
| CCRL2 | 9032 |
| CCL17 | 8999 |
| PF4 | 8801 |
| CCL22 | 8716 |
| CXCL8 | 8674 |
| CCL7 | 8148 |
| XCL1 | 7569 |
| CXCL13 | 7402 |
| CX3CL1 | 7075 |
| CCL27 | 6904 |
| CCR6 | 5675 |
| CXCL9 | 3663 |
| CCL20 | 1795 |
| CXCL11 | 1494 |
| CCR8 | 698 |
| CXCL16 | 278 |
| CXCL1 | -394 |
| CCL28 | -937 |
| CCR1 | -2124 |
| CXCL2 | -3545 |
| XCL2 | -3802 |
| CXCR4 | -4639 |
| CXCL6 | -4832 |
| XCR1 | -5197 |
| CCR10 | -5602 |
| CCL21 | -6205 |
| CXCR2 | -6351 |
| CXCL10 | -7168 |
| CXCL3 | -7445 |
| CCR3 | -7619 |
| ACKR3 | -8628 |
| CCR9 | -9041 |
| CCR4 | -9527 |
| CXCL5 | -9848 |
| ACKR4 | -10417 |
REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION
| 116 | |
|---|---|
| set | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION |
| setSize | 291 |
| pANOVA | 0.000564 |
| s.dist | 0.117 |
| p.adjustANOVA | 0.0289 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| PLG | 11348 |
| LUM | 11033 |
| FGA | 10990 |
| ITGAX | 10839 |
| MMP11 | 10822 |
| CMA1 | 10737 |
| MMP19 | 10548 |
| FBLN1 | 10511 |
| CAPN12 | 10464 |
| ICAM2 | 10341 |
| VWF | 10303 |
| COL6A6 | 10222 |
| COL1A1 | 10211 |
| CAPN11 | 10124 |
| BSG | 10115 |
| CD151 | 10054 |
| CTRB2 | 10041 |
| MMP17 | 10023 |
| ITGA11 | 10017 |
| KLK7 | 9998 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| PLG | 11348 |
| LUM | 11033 |
| FGA | 10990 |
| ITGAX | 10839 |
| MMP11 | 10822 |
| CMA1 | 10737 |
| MMP19 | 10548 |
| FBLN1 | 10511 |
| CAPN12 | 10464 |
| ICAM2 | 10341 |
| VWF | 10303 |
| COL6A6 | 10222 |
| COL1A1 | 10211 |
| CAPN11 | 10124 |
| BSG | 10115 |
| CD151 | 10054 |
| CTRB2 | 10041 |
| MMP17 | 10023 |
| ITGA11 | 10017 |
| KLK7 | 9998 |
| CEACAM6 | 9963 |
| ITGB5 | 9790 |
| ADAMTS14 | 9780 |
| P3H3 | 9776 |
| MMP3 | 9749 |
| FGG | 9690 |
| CTSK | 9665 |
| ADAM19 | 9639 |
| P4HA2 | 9637 |
| COL5A2 | 9627 |
| PCOLCE | 9555 |
| MFAP5 | 9536 |
| MMP20 | 9511 |
| MMP13 | 9430 |
| COL7A1 | 9425 |
| ITGB3 | 9362 |
| COL27A1 | 9302 |
| ICAM1 | 9224 |
| SCUBE3 | 9169 |
| TNN | 9168 |
| SCUBE1 | 8936 |
| ACAN | 8919 |
| COL13A1 | 8899 |
| SDC3 | 8890 |
| DCN | 8778 |
| TTR | 8727 |
| KLK2 | 8711 |
| ADAMTS8 | 8708 |
| SDC1 | 8643 |
| OPTC | 8611 |
| FBLN2 | 8562 |
| SH3PXD2A | 8544 |
| EMILIN3 | 8487 |
| TMPRSS6 | 8370 |
| MMP12 | 8339 |
| ADAMTS2 | 8275 |
| HSPG2 | 8255 |
| ITGA9 | 8200 |
| COL11A1 | 8001 |
| P4HB | 7917 |
| ITGB6 | 7906 |
| LRP4 | 7800 |
| PRSS1 | 7765 |
| FN1 | 7701 |
| CAPN13 | 7662 |
| ADAMTS3 | 7651 |
| COL3A1 | 7635 |
| IBSP | 7619 |
| CAPN5 | 7573 |
| MUSK | 7556 |
| LTBP3 | 7546 |
| COL9A2 | 7505 |
| COL5A1 | 7325 |
| P3H2 | 7242 |
| FURIN | 7240 |
| ICAM3 | 7069 |
| COL21A1 | 6968 |
| PTPRS | 6965 |
| COL17A1 | 6716 |
| COL15A1 | 6599 |
| ADAMTS4 | 6491 |
| LAMA5 | 6462 |
| COL4A4 | 6448 |
| MMP7 | 6396 |
| TLL2 | 6390 |
| CTSG | 6355 |
| CAPN8 | 6349 |
| COL4A3 | 6255 |
| ITGAD | 6216 |
| LAMC3 | 6118 |
| LAMC2 | 6094 |
| DST | 6061 |
| LTBP2 | 5897 |
| DSPP | 5859 |
| PECAM1 | 5768 |
| TNXB | 5764 |
| CTSD | 5558 |
| AGRN | 5535 |
| COL16A1 | 5501 |
| FGB | 5410 |
| TNR | 5378 |
| COL14A1 | 5248 |
| ITGA3 | 5152 |
| SPOCK3 | 5006 |
| EFEMP2 | 4991 |
| DDR2 | 4803 |
| SDC4 | 4768 |
| COL26A1 | 4759 |
| COL23A1 | 4736 |
| COL9A3 | 4622 |
| COL8A1 | 4608 |
| COL11A2 | 4565 |
| PDGFB | 4529 |
| COLGALT2 | 4441 |
| COL18A1 | 4423 |
| LAMA4 | 4420 |
| LOXL4 | 4402 |
| LAMA3 | 4357 |
| COL24A1 | 4330 |
| ITGAE | 4311 |
| TIMP2 | 4237 |
| ELN | 4205 |
| MADCAM1 | 4040 |
| LAMC1 | 3961 |
| PLOD2 | 3801 |
| EFEMP1 | 3683 |
| ITGB4 | 3404 |
| ITGB8 | 3243 |
| LAMA2 | 3223 |
| MATN1 | 3216 |
| P4HA1 | 3201 |
| ITGA7 | 3067 |
| ADAMTS9 | 3029 |
| MATN4 | 2988 |
| FBN1 | 2972 |
| COL9A1 | 2958 |
| HAPLN1 | 2957 |
| NID1 | 2861 |
| FGF2 | 2832 |
| ADAM17 | 2709 |
| PDGFA | 2616 |
| SPARC | 2596 |
| CAST | 2552 |
| PXDN | 2487 |
| NRXN1 | 2419 |
| TNC | 2387 |
| CD47 | 2375 |
| COL25A1 | 2347 |
| MMP24 | 2320 |
| CD44 | 2215 |
| LOXL3 | 2096 |
| ITGB1 | 2081 |
| ITGAV | 2000 |
| LTBP1 | 1954 |
| ACTN1 | 1843 |
| COL28A1 | 1712 |
| CTSV | 1674 |
| SDC2 | 1493 |
| LAMB3 | 1264 |
| MMP2 | 1263 |
| COL20A1 | 1195 |
| PPIB | 1137 |
| CASP3 | 1131 |
| FBN2 | 981 |
| MFAP3 | 947 |
| VCAN | 871 |
| ITGA8 | 818 |
| F11R | 766 |
| ADAM12 | 586 |
| BMP10 | 573 |
| ADAM8 | 529 |
| COL2A1 | 456 |
| ADAMTS18 | 407 |
| ITGA5 | 225 |
| COLGALT1 | 92 |
| CTSB | 49 |
| COL4A1 | -14 |
| CAPN9 | -38 |
| MMP10 | -103 |
| LOXL1 | -188 |
| ICAM4 | -223 |
| COL6A5 | -299 |
| JAM2 | -332 |
| ITGAM | -568 |
| NTN4 | -622 |
| VCAM1 | -768 |
| COL6A3 | -798 |
| COL4A2 | -846 |
| DAG1 | -983 |
| PRKCA | -1066 |
| BMP1 | -1162 |
| SERPINH1 | -1253 |
| NID2 | -1272 |
| PLEC | -1390 |
| BMP7 | -1430 |
| NCAN | -1445 |
| LAMA1 | -1496 |
| ADAM10 | -1547 |
| CEACAM1 | -1548 |
| MMP15 | -1754 |
| MMP9 | -1776 |
| ITGA6 | -1834 |
| TRAPPC4 | -1897 |
| FBN3 | -1916 |
| ADAMTS16 | -2106 |
| COL22A1 | -2135 |
| CAPN10 | -2191 |
| ITGA10 | -2263 |
| ITGB2 | -2405 |
| PLOD3 | -2504 |
| NCAM1 | -2556 |
| ASPN | -2645 |
| SPP1 | -2661 |
| MMP25 | -2676 |
| CAPN1 | -2768 |
| ITGA4 | -2785 |
| COL6A1 | -2788 |
| DMP1 | -2794 |
| COL19A1 | -2934 |
| TGFB2 | -3023 |
| COL6A2 | -3042 |
| LTBP4 | -3181 |
| DDR1 | -3354 |
| MMP14 | -3513 |
| CAPNS2 | -3519 |
| EMILIN2 | -3538 |
| LAMB2 | -3547 |
| MATN3 | -3753 |
| CAPN14 | -3862 |
| FBLN5 | -4056 |
| COL5A3 | -4139 |
| CDH1 | -4187 |
| COMP | -4257 |
| A2M | -4297 |
| LAMB1 | -4342 |
| ITGA2B | -4353 |
| TGFB1 | -4499 |
| GDF5 | -4502 |
| MMP16 | -4541 |
| CEACAM8 | -4546 |
| ITGB7 | -4837 |
| PSEN1 | -5004 |
| MMP8 | -5062 |
| NCSTN | -5084 |
| PHYKPL | -5203 |
| LOX | -5305 |
| ADAM15 | -5339 |
| PLOD1 | -5347 |
| ITGA2 | -5417 |
| MFAP4 | -5852 |
| ITGA1 | -5867 |
| VTN | -5978 |
| COL8A2 | -5996 |
| CAPN2 | -6075 |
| EMILIN1 | -6183 |
| HTRA1 | -6278 |
| COL12A1 | -6312 |
| CTRB1 | -6323 |
| P3H1 | -6420 |
| CAPN3 | -6440 |
| JAM3 | -6673 |
| MFAP2 | -6966 |
| P4HA3 | -7121 |
| MMP1 | -7190 |
| LOXL2 | -7220 |
| KDR | -7338 |
| ADAM9 | -7340 |
| COL1A2 | -7719 |
| ADAMTS5 | -7794 |
| ELANE | -7880 |
| BCAN | -7910 |
| PCOLCE2 | -7918 |
| CAPN7 | -7944 |
| FMOD | -8152 |
| CAPN15 | -8161 |
| APP | -8179 |
| TLL1 | -8185 |
| CTSL | -8517 |
| THBS1 | -8580 |
| ADAMTS1 | -8687 |
| CTSS | -8801 |
| CAPNS1 | -8896 |
| TGFB3 | -9022 |
| BMP2 | -9575 |
| BMP4 | -9595 |
| ICAM5 | -9618 |
| CRTAP | -9621 |
| SERPINE1 | -9678 |
| ITGAL | -9733 |
| COL10A1 | -9741 |
| KLKB1 | -9942 |
REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES
| 617 | |
|---|---|
| set | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES |
| setSize | 91 |
| pANOVA | 0.000744 |
| s.dist | -0.205 |
| p.adjustANOVA | 0.037 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| TUBA1C | -8675 |
| TUBG2 | -8420 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CKAP5 | -7526 |
| ODF2 | -7061 |
| NUMA1 | -6884 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| TUBA1C | -8675 |
| TUBG2 | -8420 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CKAP5 | -7526 |
| ODF2 | -7061 |
| NUMA1 | -6884 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| TUBB2B | -6314 |
| CEP72 | -6174 |
| HAUS5 | -6025 |
| TUBB2A | -5979 |
| TUBGCP5 | -5800 |
| TUBGCP6 | -5669 |
| CLASP1 | -5346 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CEP43 | -4973 |
| SDCCAG8 | -4735 |
| TUBA1B | -4624 |
| PCNT | -4617 |
| CEP250 | -4503 |
| CEP41 | -4178 |
| TUBA8 | -4032 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| AKAP9 | -3238 |
| CEP70 | -2717 |
| PAFAH1B1 | -2571 |
| CDK1 | -2219 |
| HAUS6 | -2029 |
| CEP290 | -2002 |
| TUBGCP3 | -1900 |
| TUBA1A | -1819 |
| CDK5RAP2 | -1570 |
| CCP110 | -1489 |
| YWHAE | -521 |
| DCTN1 | -338 |
| TUBGCP2 | -268 |
| NEK2 | -182 |
| CEP78 | 13 |
| YWHAG | 115 |
| TUBB | 261 |
| NEDD1 | 779 |
| HAUS3 | 961 |
| NME7 | 1011 |
| CENPJ | 1016 |
| TUBB1 | 1069 |
| CSNK1E | 1281 |
| CSNK1D | 1496 |
| SSNA1 | 2103 |
| ACTR1A | 2220 |
| SFI1 | 2352 |
| MAPRE1 | 2575 |
| ALMS1 | 2804 |
| TUBA3C | 3214 |
| TUBB6 | 3539 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| TUBB4A | 3612 |
| PRKAR2B | 4071 |
| HSP90AA1 | 4414 |
| PPP2R1A | 4431 |
| HAUS2 | 4581 |
| HAUS4 | 4825 |
| HAUS1 | 5311 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| PRKACA | 6168 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| MZT2B | 6651 |
| NINL | 9656 |
| TUBB8 | 11325 |
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
| 369 | |
|---|---|
| set | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL |
| setSize | 122 |
| pANOVA | 0.000768 |
| s.dist | 0.176 |
| p.adjustANOVA | 0.0371 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| LILRA1 | 11447 |
| LILRB1 | 11402 |
| SIGLEC8 | 11150 |
| CD300LG | 11047 |
| CD300LB | 11008 |
| SFTPD | 10967 |
| CD33 | 10914 |
| CLEC4G | 10635 |
| SLAMF7 | 10559 |
| LILRB2 | 10536 |
| KLRC1 | 10509 |
| CD1C | 10356 |
| ICAM2 | 10341 |
| PILRB | 10296 |
| COL1A1 | 10211 |
| SIGLEC11 | 10207 |
| KIR2DL4 | 10182 |
| ULBP3 | 10086 |
| PILRA | 10015 |
| CD300C | 9974 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| LILRA1 | 11447 |
| LILRB1 | 11402 |
| SIGLEC8 | 11150 |
| CD300LG | 11047 |
| CD300LB | 11008 |
| SFTPD | 10967 |
| CD33 | 10914 |
| CLEC4G | 10635 |
| SLAMF7 | 10559 |
| LILRB2 | 10536 |
| KLRC1 | 10509 |
| CD1C | 10356 |
| ICAM2 | 10341 |
| PILRB | 10296 |
| COL1A1 | 10211 |
| SIGLEC11 | 10207 |
| KIR2DL4 | 10182 |
| ULBP3 | 10086 |
| PILRA | 10015 |
| CD300C | 9974 |
| SIGLEC6 | 9922 |
| TREML1 | 9897 |
| CLEC2D | 9891 |
| LILRA2 | 9863 |
| SIGLEC12 | 9645 |
| LILRB3 | 9585 |
| RAET1E | 9420 |
| NPDC1 | 9250 |
| CD1A | 9242 |
| ICAM1 | 9224 |
| KLRF1 | 9162 |
| TYROBP | 8817 |
| NCR3 | 8628 |
| CD300LD | 8612 |
| TREML2 | 8504 |
| HLA-B | 8393 |
| LILRA5 | 8344 |
| LILRA4 | 8226 |
| CD19 | 8149 |
| CD40 | 7751 |
| COL3A1 | 7635 |
| SIGLEC10 | 7429 |
| CRTAM | 7361 |
| ICAM3 | 7069 |
| SIGLEC1 | 7049 |
| COLEC12 | 7035 |
| COL17A1 | 6716 |
| B2M | 6336 |
| HCST | 6070 |
| JAML | 6063 |
| KLRB1 | 5796 |
| CD247 | 5530 |
| SLAMF6 | 5213 |
| CD226 | 5196 |
| CD160 | 4866 |
| CD200R1 | 4802 |
| MADCAM1 | 4040 |
| CXADR | 3296 |
| HLA-E | 3267 |
| CLEC2B | 3209 |
| LAIR1 | 2654 |
| C3 | 2422 |
| CD300A | 2329 |
| KLRG1 | 2322 |
| LAIR2 | 2173 |
| ITGB1 | 2081 |
| FCGR3A | 2057 |
| CD1D | 1926 |
| CD3G | 1705 |
| NCR1 | 1619 |
| HLA-A | 1455 |
| HLA-C | 1395 |
| NCR3LG1 | 1371 |
| HLA-F | 1091 |
| SH2D1B | 1085 |
| CD34 | 629 |
| CD81 | 483 |
| COL2A1 | 456 |
| CD300LF | 291 |
| ICAM4 | -223 |
| LILRB4 | -674 |
| VCAM1 | -768 |
| CD3E | -959 |
| HLA-G | -1286 |
| PIANP | -2132 |
| ITGB2 | -2405 |
| NECTIN2 | -2703 |
| CD96 | -2714 |
| ITGA4 | -2785 |
| LILRA3 | -2873 |
| CD200 | -2926 |
| CD8B | -2972 |
| MICA | -4016 |
| KLRD1 | -4107 |
| CDH1 | -4187 |
| MICB | -4308 |
| CD300E | -4659 |
| ITGB7 | -4837 |
| IFITM1 | -4972 |
| CD22 | -5018 |
| SIGLEC9 | -5096 |
| PVR | -5115 |
| TREM2 | -5160 |
| SIGLEC7 | -5442 |
| CD3D | -6621 |
| KLRK1 | -6685 |
| OSCAR | -7052 |
| TREM1 | -7361 |
| CD8A | -7658 |
| NCR2 | -7716 |
| COL1A2 | -7719 |
| SIGLEC5 | -8020 |
| CD1B | -8081 |
| ULBP1 | -8615 |
| LILRB5 | -8707 |
| KIR3DL2 | -9274 |
| SELL | -9522 |
| ICAM5 | -9618 |
| TREML4 | -9675 |
| ITGAL | -9733 |
| KIR2DL1 | -9819 |
| KIR3DL1 | -9911 |
REACTOME_TRNA_PROCESSING
| 1147 | |
|---|---|
| set | REACTOME_TRNA_PROCESSING |
| setSize | 105 |
| pANOVA | 0.00082 |
| s.dist | -0.189 |
| p.adjustANOVA | 0.0385 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TRMT44 | -9689 |
| TPRKB | -9490 |
| RPP30 | -9463 |
| POM121C | -9098 |
| TRMT13 | -8738 |
| GTPBP3 | -8296 |
| POM121 | -8267 |
| RPP38 | -8229 |
| TRMT12 | -8101 |
| POP4 | -7537 |
| ELAC2 | -7531 |
| TRIT1 | -7210 |
| NUP214 | -7186 |
| CPSF4 | -7145 |
| RPPH1 | -7056 |
| ADAT3 | -7004 |
| CTU1 | -6927 |
| NUP88 | -6865 |
| NUP42 | -6551 |
| OSGEP | -6526 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TRMT44 | -9689 |
| TPRKB | -9490 |
| RPP30 | -9463 |
| POM121C | -9098 |
| TRMT13 | -8738 |
| GTPBP3 | -8296 |
| POM121 | -8267 |
| RPP38 | -8229 |
| TRMT12 | -8101 |
| POP4 | -7537 |
| ELAC2 | -7531 |
| TRIT1 | -7210 |
| NUP214 | -7186 |
| CPSF4 | -7145 |
| RPPH1 | -7056 |
| ADAT3 | -7004 |
| CTU1 | -6927 |
| NUP88 | -6865 |
| NUP42 | -6551 |
| OSGEP | -6526 |
| C2orf49 | -6371 |
| NSUN6 | -5895 |
| NUP210 | -5812 |
| TSEN54 | -5736 |
| TSEN2 | -5621 |
| LCMT2 | -5518 |
| TPR | -5490 |
| XPOT | -5469 |
| TSEN15 | -5335 |
| PUS7 | -5233 |
| TRDMT1 | -4978 |
| TRMT9B | -4920 |
| TRNT1 | -4917 |
| DDX1 | -4615 |
| WDR4 | -4599 |
| TYW3 | -4587 |
| NUP107 | -4561 |
| NUP50 | -4559 |
| NSUN2 | -4509 |
| MTO1 | -4411 |
| NUP85 | -4358 |
| NUP98 | -4330 |
| THG1L | -4151 |
| NUP43 | -3906 |
| METTL1 | -3879 |
| NUP35 | -3876 |
| RPP40 | -3737 |
| NUP133 | -3446 |
| TYW5 | -3171 |
| POP1 | -3155 |
| NUP188 | -2837 |
| URM1 | -2639 |
| NUP205 | -2593 |
| RTRAF | -2291 |
| THADA | -2156 |
| RAN | -2031 |
| QTRT2 | -1806 |
| CDKAL1 | -1675 |
| ALKBH8 | -1662 |
| RPP14 | -1649 |
| PUS1 | -1588 |
| TRMT10C | -943 |
| PUS3 | -887 |
| RPP25 | -756 |
| TRMT6 | -725 |
| NUP160 | -518 |
| NUP37 | 339 |
| FAM98B | 372 |
| CLP1 | 507 |
| TRMT61B | 514 |
| TRMU | 713 |
| SEC13 | 959 |
| RTCB | 1048 |
| EPRS1 | 1578 |
| NUP62 | 1710 |
| TRMT11 | 2070 |
| RAE1 | 2192 |
| TRMT5 | 2226 |
| NUP93 | 2760 |
| DUS2 | 2814 |
| NDC1 | 2860 |
| RANBP2 | 3016 |
| QTRT1 | 3669 |
| NUP153 | 4025 |
| NUP54 | 4170 |
| AAAS | 4254 |
| ZBTB8OS | 4282 |
| CPSF1 | 4549 |
| PRORP | 4601 |
| RPP21 | 4859 |
| TP53RK | 5080 |
| TRMT10A | 5167 |
| TRMT112 | 5339 |
| NUP58 | 5365 |
| SEH1L | 5647 |
| POP5 | 5650 |
| TYW1 | 6850 |
| TSEN34 | 7130 |
| ADAT2 | 7372 |
| NUP155 | 7411 |
| TRMT61A | 7577 |
| TRMT1 | 7949 |
| POP7 | 8958 |
| CTU2 | 9497 |
| ADAT1 | 9574 |
REACTOME_DEUBIQUITINATION
| 1000 | |
|---|---|
| set | REACTOME_DEUBIQUITINATION |
| setSize | 260 |
| pANOVA | 0.000865 |
| s.dist | -0.12 |
| p.adjustANOVA | 0.0395 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MYSM1 | -10286.0 |
| AXIN2 | -9846.0 |
| YY1 | -9556.0 |
| TAB1 | -9523.0 |
| RIPK1 | -9477.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| USP24 | -9263.0 |
| H2AC13 | -9229.0 |
| GATA3 | -9199.0 |
| UCHL1 | -9198.0 |
| USP20 | -8965.0 |
| APC | -8915.0 |
| USP19 | -8889.0 |
| PSMD2 | -8887.0 |
| TGFBR1 | -8839.0 |
| TRRAP | -8829.0 |
| PSMB11 | -8512.0 |
| NFRKB | -8306.0 |
| H2BC13 | -8199.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MYSM1 | -10286.0 |
| AXIN2 | -9846.0 |
| YY1 | -9556.0 |
| TAB1 | -9523.0 |
| RIPK1 | -9477.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| USP24 | -9263.0 |
| H2AC13 | -9229.0 |
| GATA3 | -9199.0 |
| UCHL1 | -9198.0 |
| USP20 | -8965.0 |
| APC | -8915.0 |
| USP19 | -8889.0 |
| PSMD2 | -8887.0 |
| TGFBR1 | -8839.0 |
| TRRAP | -8829.0 |
| PSMB11 | -8512.0 |
| NFRKB | -8306.0 |
| H2BC13 | -8199.0 |
| BECN1 | -7939.0 |
| USP42 | -7917.0 |
| PSMC1 | -7848.0 |
| USP30 | -7843.0 |
| ABRAXAS1 | -7840.0 |
| H2BC5 | -7799.0 |
| SMAD2 | -7644.0 |
| UFD1 | -7620.0 |
| ATXN7 | -7462.0 |
| ACTL6A | -7457.0 |
| PSMD13 | -7362.0 |
| USP10 | -7138.0 |
| EP300 | -7126.0 |
| RUVBL1 | -7114.0 |
| MCRS1 | -7069.0 |
| ACTR5 | -6918.0 |
| TNKS2 | -6894.0 |
| BIRC3 | -6858.0 |
| FOXK1 | -6778.0 |
| CDC25A | -6647.0 |
| PSMD3 | -6608.0 |
| USP13 | -6601.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| ARRB2 | -6501.0 |
| BRCA1 | -6477.0 |
| STAM | -6465.0 |
| PSMD9 | -6463.0 |
| PSMD4 | -6409.0 |
| NFKBIA | -6342.0 |
| PSMB5 | -6339.0 |
| MUL1 | -6292.0 |
| RIPK2 | -6167.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| VDAC3 | -5884.0 |
| USP15 | -5825.0 |
| H2AC6 | -5775.0 |
| H2BC15 | -5694.0 |
| STAM2 | -5604.0 |
| TNIP3 | -5600.0 |
| WDR20 | -5534.0 |
| ASXL2 | -5366.0 |
| H2BC6 | -5295.0 |
| HGS | -5275.0 |
| PSMC3 | -5262.0 |
| USP3 | -5199.0 |
| H2BC4 | -5066.0 |
| USP37 | -5056.0 |
| USP47 | -5054.0 |
| PSME4 | -5053.0 |
| AXIN1 | -5023.0 |
| STAMBP | -4909.0 |
| PSMA5 | -4888.0 |
| JOSD2 | -4887.0 |
| TADA3 | -4791.0 |
| USP14 | -4737.0 |
| PSMD5 | -4711.0 |
| ADRM1 | -4596.0 |
| TGFB1 | -4499.0 |
| H2AC15 | -4421.0 |
| UBE2D1 | -4355.0 |
| PSMB6 | -4271.0 |
| H2BC9 | -4255.5 |
| PTEN | -4219.0 |
| H2AC25 | -4201.0 |
| H2BC17 | -4192.0 |
| INO80E | -4156.0 |
| USP49 | -4092.0 |
| SNX3 | -4039.0 |
| USP48 | -3989.0 |
| PSMD1 | -3979.0 |
| TRAF6 | -3967.0 |
| OTUD3 | -3931.0 |
| RHOT1 | -3735.0 |
| NOD1 | -3630.0 |
| H2BC26 | -3582.0 |
| TNKS | -3457.0 |
| MBD6 | -3400.0 |
| ABRAXAS2 | -3369.0 |
| OTUD7B | -3194.0 |
| BAP1 | -3166.0 |
| PSMC4 | -3089.0 |
| VCP | -2987.0 |
| POLB | -2982.0 |
| SIAH2 | -2978.0 |
| ZRANB1 | -2971.0 |
| PSMB1 | -2799.0 |
| USP22 | -2756.0 |
| CYLD | -2673.0 |
| RNF123 | -2635.0 |
| KAT2A | -2607.0 |
| STAMBPL1 | -2534.0 |
| CCNA1 | -2494.0 |
| PSMA2 | -2485.0 |
| USP28 | -2444.0 |
| TAF10 | -2411.0 |
| INO80 | -2396.0 |
| OTUB1 | -2364.0 |
| CDK1 | -2219.0 |
| PSMC6 | -2126.0 |
| BABAM1 | -2123.0 |
| TADA2B | -2103.0 |
| CLSPN | -2005.0 |
| WDR48 | -1996.0 |
| MBD5 | -1933.0 |
| PSMB9 | -1684.0 |
| H2AC8 | -1573.0 |
| CCP110 | -1489.0 |
| BIRC2 | -1477.0 |
| USP33 | -1426.0 |
| PSMA3 | -1391.0 |
| PSME3 | -1153.0 |
| UCHL3 | -1106.0 |
| KAT2B | -1030.0 |
| H2BC8 | -1029.0 |
| RIGI | -659.0 |
| TP53 | -548.0 |
| PSMA1 | -477.0 |
| INO80B | -379.0 |
| TRAF3 | -323.0 |
| PSMB8 | -260.0 |
| UBA52 | -167.0 |
| USP4 | 10.0 |
| MDM4 | 110.0 |
| USP44 | 114.0 |
| H2AC17 | 251.0 |
| KDM1B | 262.0 |
| PSMB10 | 447.0 |
| RCE1 | 560.0 |
| MAP3K7 | 645.0 |
| KEAP1 | 666.0 |
| SMAD1 | 719.0 |
| MAVS | 726.0 |
| MYC | 805.0 |
| SENP8 | 850.0 |
| TNIP1 | 876.0 |
| USP8 | 888.0 |
| PSMD12 | 901.0 |
| H2AC21 | 971.0 |
| BABAM2 | 1018.0 |
| PTRH2 | 1105.0 |
| TRAF2 | 1106.0 |
| ACTR8 | 1139.0 |
| PSMD14 | 1213.0 |
| SMAD7 | 1406.0 |
| HIF1A | 1459.0 |
| USP21 | 1624.0 |
| H2AC16 | 1717.0 |
| MAT2B | 1768.0 |
| TGFBR2 | 1787.0 |
| ESR1 | 1789.0 |
| SEM1 | 1794.0 |
| DDB2 | 1829.0 |
| RPS27A | 1846.0 |
| H2BC3 | 1920.0 |
| NLRP3 | 2075.0 |
| ATXN3 | 2178.0 |
| PSMC5 | 2183.0 |
| PSMD8 | 2235.0 |
| UCHL5 | 2256.0 |
| TRIM25 | 2692.0 |
| H2BC1 | 2755.0 |
| USP34 | 2769.0 |
| USP16 | 2770.0 |
| PRKN | 2992.0 |
| RAD23B | 3038.0 |
| ARRB1 | 3054.0 |
| RNF146 | 3055.0 |
| SMAD4 | 3126.0 |
| USP2 | 3157.0 |
| INO80C | 3272.0 |
| USP5 | 3273.0 |
| UIMC1 | 3452.0 |
| TOMM70 | 3613.0 |
| H2AC11 | 3693.0 |
| VDAC1 | 3778.0 |
| YOD1 | 3858.0 |
| NEDD8 | 4083.0 |
| TRIM4 | 4255.0 |
| ADRB2 | 4307.0 |
| IFIH1 | 4344.0 |
| CCNA2 | 4366.0 |
| SUDS3 | 4380.0 |
| VDAC2 | 4743.0 |
| SKP2 | 4760.0 |
| PSMB4 | 4971.0 |
| TFPT | 5101.0 |
| ACTB | 5155.0 |
| PSMF1 | 5221.0 |
| TOMM20 | 5271.0 |
| PSMD7 | 5305.0 |
| TNFAIP3 | 5373.0 |
| RNF135 | 5408.0 |
| USP7 | 5667.0 |
| MDM2 | 5757.0 |
| CFTR | 5784.0 |
| IDE | 5797.0 |
| PSMB2 | 5803.0 |
| PSMB7 | 5858.0 |
| H2AC1 | 5861.0 |
| INO80D | 6156.0 |
| USP18 | 6237.0 |
| FKBP8 | 6364.0 |
| H2BC11 | 6454.0 |
| PSMA8 | 6502.0 |
| PSMD6 | 6616.0 |
| JOSD1 | 6631.0 |
| PSME2 | 6638.0 |
| H2AC12 | 6666.0 |
| UBC | 6700.0 |
| OTUB2 | 6781.0 |
| H2AC4 | 6905.0 |
| ASXL1 | 6941.0 |
| PSMA6 | 6984.0 |
| FOXK2 | 7105.0 |
| CDC20 | 7234.0 |
| TNIP2 | 7285.0 |
| H2BC21 | 7408.0 |
| NOD2 | 7481.0 |
| PSMA4 | 7568.0 |
| UBB | 7594.0 |
| VCPIP1 | 7652.0 |
| H2BC12 | 7676.0 |
| RHOA | 7838.0 |
| SMAD3 | 7915.0 |
| PSMB3 | 8017.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| SMURF2 | 8269.0 |
| OTUD7A | 8369.0 |
| H2AC20 | 8750.0 |
| USP12 | 9184.0 |
| RAD23A | 9233.0 |
| H2AC14 | 9376.0 |
| PSMA7 | 9563.0 |
| PSME1 | 9765.0 |
| USP25 | 9841.0 |
| IL33 | 10100.0 |
| H2BC14 | 10168.0 |
REACTOME_MITOTIC_PROPHASE
| 1093 | |
|---|---|
| set | REACTOME_MITOTIC_PROPHASE |
| setSize | 134 |
| pANOVA | 0.000898 |
| s.dist | -0.166 |
| p.adjustANOVA | 0.0399 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| GOLGA2 | -9392.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| POM121C | -9098.0 |
| CCNB1 | -8935.0 |
| LEMD2 | -8856.0 |
| RB1 | -8714.0 |
| RAB2A | -8702.0 |
| H4C13 | -8603.0 |
| POM121 | -8267.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| H2BC5 | -7799.0 |
| BLZF1 | -7718.0 |
| H2AX | -7648.0 |
| GORASP2 | -7497.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| GOLGA2 | -9392.0 |
| VRK1 | -9290.0 |
| H3C4 | -9267.0 |
| PPP2R1B | -9252.0 |
| POM121C | -9098.0 |
| CCNB1 | -8935.0 |
| LEMD2 | -8856.0 |
| RB1 | -8714.0 |
| RAB2A | -8702.0 |
| H4C13 | -8603.0 |
| POM121 | -8267.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| H2BC5 | -7799.0 |
| BLZF1 | -7718.0 |
| H2AX | -7648.0 |
| GORASP2 | -7497.0 |
| PPP2R2D | -7485.0 |
| H3C6 | -7372.0 |
| GORASP1 | -7335.0 |
| NUP214 | -7186.0 |
| NCAPH2 | -7155.0 |
| NCAPG2 | -7020.0 |
| CCNB2 | -6945.0 |
| NUMA1 | -6884.0 |
| NUP88 | -6865.0 |
| NCAPD3 | -6668.0 |
| PLK1 | -6633.0 |
| SMC2 | -6571.0 |
| NUP42 | -6551.0 |
| H2BC10 | -6510.0 |
| NUP210 | -5812.0 |
| H2AC6 | -5775.0 |
| H2BC15 | -5694.0 |
| LMNB1 | -5639.0 |
| H3C11 | -5538.0 |
| TPR | -5490.0 |
| H3-4 | -5447.0 |
| H2BC6 | -5295.0 |
| CNEP1R1 | -5168.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| PRKCB | -4898.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| H4C6 | -4534.0 |
| NUP85 | -4358.0 |
| NUP98 | -4330.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| H2BC17 | -4192.0 |
| USO1 | -4080.0 |
| NUP43 | -3906.0 |
| NUP35 | -3876.0 |
| H4C4 | -3867.0 |
| H2AJ | -3814.0 |
| H2BC26 | -3582.0 |
| NUP133 | -3446.0 |
| LPIN1 | -2997.0 |
| NUP188 | -2837.0 |
| LEMD3 | -2627.0 |
| NUP205 | -2593.0 |
| H4C11 | -2488.0 |
| MCPH1 | -2431.0 |
| CDK1 | -2219.0 |
| LPIN3 | -2143.0 |
| LPIN2 | -2033.0 |
| H3C10 | -1789.0 |
| TMPO | -1743.0 |
| H2AC8 | -1573.0 |
| PRKCA | -1066.0 |
| H2BC8 | -1029.0 |
| NEK7 | -599.0 |
| NUP160 | -518.0 |
| H2AZ2 | -340.0 |
| H3-3B | -135.0 |
| MAPK1 | 78.0 |
| NUP37 | 339.0 |
| VRK2 | 465.0 |
| RAB1B | 777.0 |
| SMC4 | 787.0 |
| BANF1 | 835.0 |
| H4C5 | 878.0 |
| ENSA | 893.0 |
| SEC13 | 959.0 |
| NUP62 | 1710.0 |
| CTDNEP1 | 1909.0 |
| H2BC3 | 1920.0 |
| RAE1 | 2192.0 |
| MAPK3 | 2444.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| NDC1 | 2860.0 |
| RANBP2 | 3016.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| PPP2CB | 3417.0 |
| NEK9 | 3481.0 |
| H3C2 | 3915.0 |
| NUP153 | 4025.0 |
| NUP54 | 4170.0 |
| AAAS | 4254.0 |
| H3-3A | 4335.0 |
| PPP2CA | 4421.0 |
| PPP2R1A | 4431.0 |
| RAB1A | 4669.0 |
| NEK6 | 5041.0 |
| H4C3 | 5053.0 |
| LMNA | 5119.0 |
| KMT5A | 5304.0 |
| NUP58 | 5365.0 |
| SEH1L | 5647.0 |
| H3C3 | 5902.0 |
| H3C1 | 6001.0 |
| MASTL | 6217.0 |
| ARPP19 | 6373.0 |
| H2BC11 | 6454.0 |
| H2AC4 | 6905.0 |
| H2BC21 | 7408.0 |
| NUP155 | 7411.0 |
| H2BC12 | 7676.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| SET | 8685.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| H2AZ1 | 8917.0 |
| H2AC14 | 9376.0 |
| H4C9 | 9492.0 |
| H4C12 | 10027.0 |
| H2BC14 | 10168.0 |
REACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF
| 504 | |
|---|---|
| set | REACTOME_FORMATION_OF_SENESCENCE_ASSOCIATED_HETEROCHROMATIN_FOCI_SAHF |
| setSize | 17 |
| pANOVA | 0.000953 |
| s.dist | -0.463 |
| p.adjustANOVA | 0.0407 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H1-5 | -9805 |
| UBN1 | -9294 |
| H1-3 | -9268 |
| H1-0 | -8905 |
| RB1 | -8714 |
| H1-1 | -8637 |
| EP400 | -7235 |
| LMNB1 | -5639 |
| CABIN1 | -4929 |
| CDKN1A | -3164 |
| ASF1A | -2533 |
| HMGA2 | -2404 |
| TP53 | -548 |
| H1-2 | -81 |
| HIRA | 126 |
| H1-4 | 1492 |
| HMGA1 | 2278 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H1-5 | -9805 |
| UBN1 | -9294 |
| H1-3 | -9268 |
| H1-0 | -8905 |
| RB1 | -8714 |
| H1-1 | -8637 |
| EP400 | -7235 |
| LMNB1 | -5639 |
| CABIN1 | -4929 |
| CDKN1A | -3164 |
| ASF1A | -2533 |
| HMGA2 | -2404 |
| TP53 | -548 |
| H1-2 | -81 |
| HIRA | 126 |
| H1-4 | 1492 |
| HMGA1 | 2278 |
REACTOME_CELLULAR_RESPONSES_TO_STIMULI
| 1314 | |
|---|---|
| set | REACTOME_CELLULAR_RESPONSES_TO_STIMULI |
| setSize | 779 |
| pANOVA | 0.000972 |
| s.dist | -0.0695 |
| p.adjustANOVA | 0.0407 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| MT1A | -10208.0 |
| MT1G | -10200.0 |
| MT1M | -10187.0 |
| MT1H | -10183.0 |
| PDIA5 | -9839.0 |
| H1-5 | -9805.0 |
| ETS2 | -9684.0 |
| HBA1 | -9509.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| DNAJB1 | -9446.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SZT2 | -9379.0 |
| KHSRP | -9345.0 |
| PHC1 | -9332.0 |
| ST13 | -9300.0 |
| UBN1 | -9294.0 |
| H1-3 | -9268.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323.0 |
| MT1A | -10208.0 |
| MT1G | -10200.0 |
| MT1M | -10187.0 |
| MT1H | -10183.0 |
| PDIA5 | -9839.0 |
| H1-5 | -9805.0 |
| ETS2 | -9684.0 |
| HBA1 | -9509.0 |
| UBE2C | -9474.0 |
| H3C12 | -9458.0 |
| DNAJB1 | -9446.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| SZT2 | -9379.0 |
| KHSRP | -9345.0 |
| PHC1 | -9332.0 |
| ST13 | -9300.0 |
| UBN1 | -9294.0 |
| H1-3 | -9268.0 |
| H3C4 | -9267.0 |
| ATP6V0E2 | -9165.0 |
| CYCS | -9162.0 |
| COX6C | -9132.0 |
| TFDP1 | -9109.0 |
| POM121C | -9098.0 |
| HBA2 | -9089.0 |
| RPS23 | -9035.0 |
| TUBB4B | -9023.0 |
| MT1E | -8980.0 |
| CUL2 | -8973.0 |
| H1-0 | -8905.0 |
| PSMD2 | -8887.0 |
| IGFBP1 | -8861.0 |
| GCN1 | -8827.0 |
| PALB2 | -8722.0 |
| EIF2S2 | -8715.0 |
| RB1 | -8714.0 |
| SUZ12 | -8683.0 |
| TUBA1C | -8675.0 |
| APOB | -8669.0 |
| ANAPC5 | -8661.0 |
| H1-1 | -8637.0 |
| H4C13 | -8603.0 |
| GPX2 | -8521.0 |
| PSMB11 | -8512.0 |
| RPL32 | -8431.0 |
| MIR24-1 | -8393.0 |
| CCAR2 | -8339.0 |
| ATP6V1H | -8321.0 |
| SNCB | -8314.0 |
| FLCN | -8309.0 |
| TXN | -8297.0 |
| TUBA3E | -8293.0 |
| POM121 | -8267.0 |
| HSPA14 | -8233.0 |
| HSPA4L | -8204.0 |
| H2BC13 | -8199.0 |
| IL6 | -8175.0 |
| MAPK9 | -8174.0 |
| CREB3L4 | -8138.0 |
| TERF1 | -8123.0 |
| MTOR | -8114.0 |
| H4C16 | -8109.0 |
| LY96 | -8055.0 |
| PPARA | -8024.0 |
| NR3C2 | -7900.0 |
| WDR24 | -7862.0 |
| SIN3B | -7854.0 |
| PSMC1 | -7848.0 |
| MAPKAPK5 | -7833.0 |
| ANAPC4 | -7831.0 |
| H2BC5 | -7799.0 |
| HSPA1L | -7773.0 |
| RPA1 | -7755.0 |
| ATP6V1G3 | -7728.0 |
| RPL34 | -7701.0 |
| H2AX | -7648.0 |
| UFD1 | -7620.0 |
| EPO | -7592.0 |
| DYNLL2 | -7477.0 |
| PGR | -7470.0 |
| H3C6 | -7372.0 |
| RPL26 | -7370.0 |
| PSMD13 | -7362.0 |
| BTRC | -7343.0 |
| NCOA6 | -7292.0 |
| CUL7 | -7243.0 |
| EP400 | -7235.0 |
| NUP214 | -7186.0 |
| EP300 | -7126.0 |
| NCOR2 | -7068.0 |
| SLC7A11 | -7045.0 |
| PARN | -6996.0 |
| GPX5 | -6972.0 |
| CDKN1B | -6954.0 |
| EIF2AK4 | -6917.0 |
| PRDX2 | -6868.0 |
| NUP88 | -6865.0 |
| NCOA1 | -6850.0 |
| COX18 | -6827.0 |
| EGLN3 | -6759.0 |
| COX7A2L | -6753.0 |
| ATP6V1C1 | -6746.0 |
| CBX8 | -6701.0 |
| IMPACT | -6682.0 |
| PRDX1 | -6636.0 |
| TUBA4A | -6626.0 |
| PSMD3 | -6608.0 |
| HSPA6 | -6568.0 |
| DCTN3 | -6556.0 |
| NUP42 | -6551.0 |
| BMAL1 | -6531.0 |
| MED1 | -6514.0 |
| H2BC10 | -6510.0 |
| HSPH1 | -6500.0 |
| EXOSC3 | -6479.0 |
| ATP6V0D1 | -6478.0 |
| BRCA1 | -6477.0 |
| NR1D1 | -6475.0 |
| DYNC1H1 | -6464.0 |
| PSMD9 | -6463.0 |
| PSMD4 | -6409.0 |
| PSMB5 | -6339.0 |
| TUBB2B | -6314.0 |
| MUL1 | -6292.0 |
| NFYA | -6252.0 |
| FAU | -6249.0 |
| EXOSC7 | -6246.0 |
| RPTOR | -6228.0 |
| EGLN1 | -6227.0 |
| HSPA4 | -6218.0 |
| DNAJB11 | -6207.0 |
| MOV10 | -6196.0 |
| ACADVL | -6195.0 |
| CREBRF | -6192.0 |
| EHMT2 | -6169.0 |
| SURF1 | -6162.0 |
| VENTX | -6123.0 |
| TINF2 | -6121.0 |
| SEC31A | -6085.0 |
| CSNK2B | -6080.0 |
| PSMD11 | -6044.0 |
| PSMC2 | -6032.0 |
| TUBB2A | -5979.0 |
| ID1 | -5961.0 |
| ATP6V1G1 | -5938.0 |
| RPS20 | -5836.0 |
| NUP210 | -5812.0 |
| RPS19BP1 | -5808.0 |
| ANAPC7 | -5789.0 |
| HSPA1B | -5776.0 |
| H2AC6 | -5775.0 |
| ATP6V1C2 | -5758.0 |
| CBX4 | -5719.0 |
| H2BC15 | -5694.0 |
| AKT3 | -5680.0 |
| TRIB3 | -5663.0 |
| EHMT1 | -5643.0 |
| LMNB1 | -5639.0 |
| NPLOC4 | -5638.0 |
| H3C11 | -5538.0 |
| RPL31 | -5535.0 |
| TPR | -5490.0 |
| FOS | -5453.0 |
| H3-4 | -5447.0 |
| CRTC3 | -5423.0 |
| AKT2 | -5419.0 |
| HMOX2 | -5379.0 |
| ATP6V0E1 | -5354.0 |
| CBX6 | -5319.0 |
| MAP2K6 | -5315.0 |
| RPS16 | -5300.0 |
| NR3C1 | -5298.0 |
| H2BC6 | -5295.0 |
| SLC38A9 | -5278.0 |
| PSMC3 | -5262.0 |
| RPL10A | -5247.0 |
| ATM | -5218.0 |
| DYNC1I2 | -5131.0 |
| RPS6 | -5123.0 |
| FKBP5 | -5112.0 |
| RPL36AL | -5105.5 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| E2F2 | -5059.0 |
| PSME4 | -5053.0 |
| TUBAL3 | -5043.0 |
| SRXN1 | -5030.0 |
| RPL24 | -5029.0 |
| TUBA4B | -5020.0 |
| HELZ2 | -5011.0 |
| RPS7 | -5010.0 |
| CUL3 | -4960.0 |
| CABIN1 | -4929.0 |
| AJUBA | -4908.0 |
| RPS13 | -4901.0 |
| PSMA5 | -4888.0 |
| PLA2G4B | -4871.0 |
| DNAJA2 | -4849.0 |
| CLOCK | -4846.0 |
| HIGD1A | -4810.0 |
| CDC23 | -4806.0 |
| NFE2L2 | -4792.0 |
| TFDP2 | -4787.0 |
| CDC27 | -4761.0 |
| DYNC1LI2 | -4730.0 |
| PSMD5 | -4711.0 |
| HSPA2 | -4704.0 |
| CDKN2A | -4700.0 |
| GFPT1 | -4666.0 |
| TNRC6C | -4643.0 |
| RPL9 | -4637.0 |
| EED | -4626.0 |
| TUBA1B | -4624.0 |
| SP1 | -4623.0 |
| NUP107 | -4561.0 |
| NUP50 | -4559.0 |
| RPL22 | -4542.0 |
| RPL29 | -4535.0 |
| H4C6 | -4534.0 |
| DNAJB6 | -4487.0 |
| TXN2 | -4474.0 |
| ACTR10 | -4445.0 |
| NUP85 | -4358.0 |
| UBE2D1 | -4355.0 |
| XPO1 | -4345.0 |
| NUP98 | -4330.0 |
| CXXC1 | -4304.0 |
| PSMB6 | -4271.0 |
| RPS12 | -4260.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| WDR59 | -4230.0 |
| TACO1 | -4214.0 |
| H2BC17 | -4192.0 |
| MAFG | -4189.0 |
| TNIK | -4166.0 |
| CAPZB | -4153.0 |
| CRYBA4 | -4140.0 |
| HSP90AB1 | -4117.0 |
| UBE2E1 | -4108.0 |
| GPX3 | -4094.0 |
| PHC2 | -4060.0 |
| NCOA2 | -4049.0 |
| TNRC6A | -4043.0 |
| RAD50 | -4035.0 |
| TUBA8 | -4032.0 |
| GOSR2 | -4003.0 |
| PSMD1 | -3979.0 |
| HM13 | -3969.0 |
| HYOU1 | -3940.0 |
| NUP43 | -3906.0 |
| RPS26 | -3889.0 |
| SSR1 | -3881.0 |
| NUP35 | -3876.0 |
| DCTN4 | -3874.0 |
| H4C4 | -3867.0 |
| DCSTAMP | -3832.0 |
| BMI1 | -3827.0 |
| H2AJ | -3814.0 |
| DNAJC7 | -3795.0 |
| YIF1A | -3747.0 |
| ANAPC2 | -3617.0 |
| TERF2IP | -3592.0 |
| SRPRA | -3587.0 |
| H2BC26 | -3582.0 |
| KDELR3 | -3573.0 |
| BAG5 | -3570.0 |
| KICS2 | -3564.0 |
| HIF1AN | -3557.0 |
| DYNLL1 | -3550.0 |
| NUP133 | -3446.0 |
| BAG3 | -3432.0 |
| MAP4K4 | -3301.0 |
| RPS3A | -3283.0 |
| CREBBP | -3271.0 |
| ASNS | -3251.0 |
| HSPA9 | -3249.0 |
| ATF2 | -3228.0 |
| ANAPC15 | -3203.0 |
| CDKN1A | -3164.0 |
| ADD1 | -3157.0 |
| COX11 | -3091.0 |
| PSMC4 | -3089.0 |
| MAP2K4 | -3031.0 |
| LAMTOR2 | -3018.0 |
| NPRL3 | -3006.0 |
| VCP | -2987.0 |
| ATF6 | -2967.0 |
| NFYC | -2954.0 |
| RING1 | -2953.0 |
| MAPK14 | -2900.0 |
| DNAJC2 | -2894.0 |
| RPL8 | -2868.0 |
| CCS | -2850.0 |
| NUP188 | -2837.0 |
| NDUFA4 | -2835.0 |
| VEGFA | -2830.0 |
| PSMB1 | -2799.0 |
| NFKB1 | -2707.0 |
| MAPKAPK2 | -2687.0 |
| EXOSC4 | -2680.0 |
| GSK3B | -2665.0 |
| TGS1 | -2634.0 |
| LAMTOR4 | -2598.0 |
| NUP205 | -2593.0 |
| E2F3 | -2555.0 |
| ASF1A | -2533.0 |
| CCNA1 | -2494.0 |
| FNIP1 | -2492.0 |
| H4C11 | -2488.0 |
| PSMA2 | -2485.0 |
| MAP2K7 | -2474.0 |
| MT1F | -2472.0 |
| RPL14 | -2453.0 |
| HMGA2 | -2404.0 |
| VHL | -2369.0 |
| AGO4 | -2358.0 |
| LAMTOR3 | -2319.0 |
| CDK6 | -2302.0 |
| UBE2D3 | -2295.0 |
| CSRP1 | -2286.0 |
| KDM6B | -2147.0 |
| PSMC6 | -2126.0 |
| TNRC6B | -2096.0 |
| DYNC1I1 | -2088.0 |
| EDEM1 | -2043.0 |
| EXOSC2 | -2039.0 |
| EPAS1 | -2034.0 |
| CSNK2A2 | -2019.0 |
| RPL38 | -2006.0 |
| PRDX6 | -1966.0 |
| KAT5 | -1955.0 |
| BMT2 | -1949.0 |
| TLN1 | -1936.0 |
| CAT | -1927.0 |
| EXTL3 | -1904.0 |
| LIMD1 | -1895.0 |
| SESN1 | -1880.0 |
| SOD2 | -1874.0 |
| HDAC3 | -1872.0 |
| TUBA1A | -1819.0 |
| ANAPC16 | -1795.0 |
| H3C10 | -1789.0 |
| XBP1 | -1699.0 |
| PSMB9 | -1684.0 |
| ATR | -1677.0 |
| RPS21 | -1653.0 |
| CASTOR1 | -1605.0 |
| H2AC8 | -1573.0 |
| DNAJC3 | -1571.0 |
| ATP6V1B2 | -1556.0 |
| SCMH1 | -1534.0 |
| PTGES3 | -1520.0 |
| PSMA3 | -1391.0 |
| RPS6KA2 | -1273.0 |
| AGO3 | -1258.0 |
| SERPINH1 | -1253.0 |
| NCOR1 | -1234.0 |
| MAPK7 | -1222.0 |
| HIF3A | -1197.0 |
| FBXL17 | -1187.0 |
| PSME3 | -1153.0 |
| MAPKAPK3 | -1139.0 |
| EZH2 | -1086.0 |
| CDKN2C | -1068.0 |
| H2BC8 | -1029.0 |
| LAMTOR1 | -1023.0 |
| ANAPC11 | -1014.0 |
| EIF2AK3 | -953.0 |
| RNF2 | -892.0 |
| TALDO1 | -881.0 |
| GML | -827.0 |
| RPL21 | -801.0 |
| CARM1 | -800.0 |
| DCP2 | -774.0 |
| HSPB1 | -744.0 |
| PPARGC1A | -698.0 |
| PPP1R15A | -681.0 |
| USP46 | -675.0 |
| RPL5 | -602.0 |
| TXNIP | -589.0 |
| TP53 | -548.0 |
| YWHAE | -521.0 |
| NUP160 | -518.0 |
| PSMA1 | -477.0 |
| RPL41 | -362.0 |
| RPL37 | -341.0 |
| H2AZ2 | -340.0 |
| DCTN1 | -338.0 |
| RPSA | -319.0 |
| SKP1 | -264.0 |
| PSMB8 | -260.0 |
| EIF2AK1 | -257.0 |
| COX5B | -246.0 |
| NOX4 | -202.0 |
| UBA52 | -167.0 |
| H3-3B | -135.0 |
| H1-2 | -81.0 |
| RRAGA | -77.0 |
| SIN3A | -32.0 |
| MBTPS1 | -25.0 |
| NFYB | 8.0 |
| TLR4 | 14.0 |
| GPX1 | 38.0 |
| BAG2 | 62.0 |
| RAI1 | 72.0 |
| MAPK1 | 78.0 |
| MIOS | 94.0 |
| MAP3K5 | 109.0 |
| MDM4 | 110.0 |
| HIRA | 126.0 |
| APOA1 | 129.0 |
| BAG4 | 132.0 |
| ATP6V0B | 148.0 |
| MT1B | 154.0 |
| RPS10 | 170.0 |
| IFNB1 | 190.0 |
| COX6B1 | 196.0 |
| RRAGD | 285.0 |
| CREB3 | 322.0 |
| MYDGF | 331.0 |
| NUP37 | 339.0 |
| BACH1 | 358.0 |
| MAPK8 | 364.0 |
| RPL27 | 366.0 |
| RRAGC | 377.0 |
| CREB1 | 391.0 |
| RPL37A | 393.0 |
| SRPRB | 403.0 |
| KPTN | 408.0 |
| PSMB10 | 447.0 |
| ERF | 544.0 |
| POT1 | 546.0 |
| RPS11 | 572.0 |
| GCLC | 574.0 |
| KEAP1 | 666.0 |
| CAPZA1 | 768.0 |
| ATP6V1G2 | 776.0 |
| MYC | 805.0 |
| RPL27A | 807.0 |
| RPS15A | 825.0 |
| H4C5 | 878.0 |
| PSMD12 | 901.0 |
| SEC13 | 959.0 |
| CAPZA2 | 982.0 |
| CDC16 | 1047.0 |
| ME1 | 1056.0 |
| TUBB1 | 1069.0 |
| NQO1 | 1075.0 |
| WTIP | 1169.0 |
| RPA2 | 1210.0 |
| DEDD2 | 1211.0 |
| PSMD14 | 1213.0 |
| FZR1 | 1228.0 |
| CREB3L3 | 1234.0 |
| DNAJB9 | 1261.0 |
| GSR | 1300.0 |
| PHC3 | 1319.0 |
| CITED2 | 1320.0 |
| RPL18 | 1337.0 |
| RPS14 | 1389.0 |
| ABCC1 | 1428.0 |
| GRB10 | 1433.0 |
| ETS1 | 1451.0 |
| HIF1A | 1459.0 |
| SMARCD3 | 1464.0 |
| TATDN2 | 1473.0 |
| NOTCH1 | 1475.0 |
| H1-4 | 1492.0 |
| ATF4 | 1515.0 |
| HSPB8 | 1579.0 |
| GPX7 | 1589.0 |
| MAPK11 | 1621.0 |
| EXTL2 | 1627.0 |
| NUP62 | 1710.0 |
| CTDSP2 | 1741.0 |
| ATP6V1A | 1763.0 |
| SEM1 | 1794.0 |
| CEBPB | 1814.0 |
| COX20 | 1840.0 |
| RPS27A | 1846.0 |
| SHC1 | 1868.0 |
| TERF2 | 1872.0 |
| HSPA12B | 1901.0 |
| H2BC3 | 1920.0 |
| RPS19 | 1922.0 |
| BAG1 | 1945.0 |
| ATP6V1F | 1958.0 |
| HSPA5 | 2025.0 |
| CSNK2A1 | 2040.0 |
| HSPA1A | 2049.0 |
| NLRP3 | 2075.0 |
| MEF2C | 2082.0 |
| TKT | 2123.0 |
| DNAJA1 | 2134.0 |
| RPS6KA1 | 2135.0 |
| DNAJA4 | 2139.0 |
| CBX2 | 2171.0 |
| PSMC5 | 2183.0 |
| TBL1XR1 | 2184.0 |
| CA9 | 2185.0 |
| RAE1 | 2192.0 |
| ACTR1A | 2220.0 |
| PSMD8 | 2235.0 |
| CHD9 | 2242.0 |
| JUN | 2245.0 |
| HMGA1 | 2278.0 |
| COX4I1 | 2297.0 |
| ARNT | 2360.0 |
| CRTC1 | 2400.0 |
| IGFBP7 | 2406.0 |
| UBXN7 | 2443.0 |
| MAPK3 | 2444.0 |
| ATP6V1D | 2482.0 |
| HSF1 | 2670.0 |
| GSTA3 | 2675.0 |
| RPL17 | 2714.0 |
| MAFK | 2734.0 |
| H2BC1 | 2755.0 |
| NUP93 | 2760.0 |
| RORA | 2763.0 |
| CAMK2D | 2790.0 |
| NDC1 | 2860.0 |
| RPL13 | 2891.0 |
| E2F1 | 2922.0 |
| RPS25 | 2926.0 |
| FNIP2 | 2937.0 |
| RANBP2 | 3016.0 |
| DEPDC5 | 3049.0 |
| RPL23A | 3129.0 |
| TUBA3C | 3214.0 |
| COX16 | 3242.0 |
| NCF2 | 3284.0 |
| NCF4 | 3303.0 |
| RELA | 3308.0 |
| RPS27L | 3361.0 |
| H4C8 | 3367.0 |
| DIS3 | 3384.0 |
| H4C2 | 3408.0 |
| NRIP1 | 3416.0 |
| EEF1A1 | 3449.0 |
| PGD | 3454.0 |
| NBN | 3478.0 |
| RPL35 | 3496.0 |
| ERO1A | 3520.0 |
| RPS29 | 3531.0 |
| MRPL18 | 3538.0 |
| TUBB6 | 3539.0 |
| RPL3 | 3541.0 |
| TCIRG1 | 3585.0 |
| CDC26 | 3611.0 |
| TUBB4A | 3612.0 |
| SIRT1 | 3614.0 |
| CRTC2 | 3642.0 |
| RPL10L | 3682.0 |
| HDGF | 3687.0 |
| LRPPRC | 3717.0 |
| RXRA | 3719.0 |
| ALB | 3805.0 |
| EGLN2 | 3813.0 |
| TPP1 | 3843.0 |
| SQSTM1 | 3845.0 |
| NPRL2 | 3850.0 |
| TXNRD1 | 3866.0 |
| TRIM21 | 3902.0 |
| ITFG2 | 3903.0 |
| H3C2 | 3915.0 |
| ARFGAP1 | 3928.0 |
| NUP153 | 4025.0 |
| AKT1S1 | 4033.0 |
| EIF2S1 | 4095.0 |
| NUP54 | 4170.0 |
| PPP2R5B | 4232.0 |
| AAAS | 4254.0 |
| CEBPG | 4265.0 |
| CCNE2 | 4280.0 |
| ATF3 | 4285.0 |
| H3-3A | 4335.0 |
| ACD | 4346.5 |
| CCNA2 | 4366.0 |
| RBBP4 | 4375.0 |
| CUL1 | 4399.0 |
| NPAS2 | 4406.0 |
| HSP90AA1 | 4414.0 |
| HERPUD1 | 4457.0 |
| RPA3 | 4481.0 |
| HSP90B1 | 4519.0 |
| ELOC | 4538.0 |
| CDK4 | 4604.0 |
| CREB3L2 | 4637.0 |
| RPL12 | 4672.0 |
| AKT1 | 4674.0 |
| MT3 | 4698.0 |
| IDH1 | 4741.0 |
| SKP2 | 4760.0 |
| RPS2 | 4762.0 |
| CALR | 4769.0 |
| DPP3 | 4774.0 |
| RPL35A | 4775.0 |
| ATOX1 | 4809.0 |
| PDIA6 | 4836.0 |
| GSK3A | 4851.0 |
| PSMB4 | 4971.0 |
| CAMK2B | 4977.0 |
| DCTN6 | 4994.0 |
| CLEC1B | 5014.0 |
| PRDX5 | 5040.0 |
| H4C3 | 5053.0 |
| LMNA | 5119.0 |
| MTF1 | 5123.0 |
| RPL15 | 5129.0 |
| MINK1 | 5131.0 |
| EXOSC5 | 5141.0 |
| CDK2 | 5165.0 |
| HBB | 5191.0 |
| PSMF1 | 5221.0 |
| EXOSC8 | 5240.0 |
| RPL30 | 5251.0 |
| ATP6V1E1 | 5273.0 |
| PSMD7 | 5305.0 |
| SCO1 | 5321.0 |
| ATF5 | 5362.0 |
| NUP58 | 5365.0 |
| NUDT2 | 5403.0 |
| CYBA | 5406.0 |
| UBE2S | 5479.0 |
| MRE11 | 5531.0 |
| RPL13A | 5555.5 |
| TNFRSF21 | 5588.0 |
| EXOSC1 | 5589.0 |
| RPS15 | 5609.0 |
| SERP1 | 5646.0 |
| SEH1L | 5647.0 |
| MLST8 | 5663.0 |
| RPS27 | 5679.0 |
| MDM2 | 5757.0 |
| PSMB2 | 5803.0 |
| RPL36 | 5850.0 |
| PSMB7 | 5858.0 |
| H3C3 | 5902.0 |
| NOX5 | 5917.0 |
| DDIT3 | 5939.0 |
| FKBP14 | 5953.0 |
| H3C1 | 6001.0 |
| FKBP4 | 6077.0 |
| RPL11 | 6162.0 |
| COX7C | 6164.0 |
| TUBB3 | 6221.0 |
| DCTN2 | 6256.0 |
| EXOSC6 | 6261.0 |
| RPL7 | 6313.0 |
| RPL4 | 6383.0 |
| RPL23 | 6429.0 |
| H2BC11 | 6454.0 |
| ANAPC10 | 6467.0 |
| PSMA8 | 6502.0 |
| UBE2D2 | 6564.0 |
| PSMD6 | 6616.0 |
| PSME2 | 6638.0 |
| WIPI1 | 6648.0 |
| RPS3 | 6659.0 |
| RPLP1 | 6672.0 |
| RPL19 | 6685.0 |
| UBC | 6700.0 |
| RPL39L | 6704.0 |
| GPX6 | 6756.0 |
| RPS28 | 6787.0 |
| SH3BP4 | 6800.0 |
| DYNC1LI1 | 6830.0 |
| RPL26L1 | 6861.0 |
| RPS18 | 6884.0 |
| PREB | 6900.0 |
| H2AC4 | 6905.0 |
| TXNRD2 | 6939.0 |
| PSMA6 | 6984.0 |
| AQP8 | 6993.0 |
| LAMTOR5 | 7006.0 |
| GCLM | 7015.0 |
| PRKCD | 7089.0 |
| RPL28 | 7094.0 |
| CHAC1 | 7225.0 |
| ATP6V0D2 | 7246.0 |
| COX8A | 7254.0 |
| AGO1 | 7256.0 |
| MAPK10 | 7289.0 |
| BLVRA | 7359.0 |
| RHEB | 7364.0 |
| H2BC21 | 7408.0 |
| NUP155 | 7411.0 |
| COX19 | 7426.0 |
| HIKESHI | 7435.0 |
| DCTN5 | 7453.0 |
| CCNE1 | 7482.0 |
| RPL22L1 | 7521.0 |
| CDKN2B | 7557.0 |
| PSMA4 | 7568.0 |
| HMOX1 | 7583.0 |
| UBB | 7594.0 |
| RPS8 | 7606.0 |
| MAP2K3 | 7631.0 |
| H2BC12 | 7676.0 |
| STAP2 | 7713.0 |
| HSPA12A | 7715.0 |
| KLHDC3 | 7732.0 |
| HSPA8 | 7737.0 |
| STIP1 | 7846.0 |
| MT4 | 7874.0 |
| STAT3 | 7887.0 |
| P4HB | 7917.0 |
| MT2A | 7966.0 |
| PSMB3 | 8017.0 |
| RPL6 | 8034.0 |
| WFS1 | 8124.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| BLVRB | 8211.0 |
| ATP6V1E2 | 8273.0 |
| ATP6V0C | 8420.0 |
| EXOSC9 | 8477.0 |
| CREB3L1 | 8541.0 |
| CXCL8 | 8674.0 |
| SOD1 | 8726.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| MT1X | 8811.0 |
| RPS5 | 8900.0 |
| H2AZ1 | 8917.0 |
| SOD3 | 8926.0 |
| ATP6V1B1 | 8963.0 |
| RPLP0 | 8964.0 |
| MAP1LC3B | 8987.0 |
| HSPA13 | 8995.0 |
| SYVN1 | 9031.0 |
| CAMK2G | 9035.0 |
| PRDX3 | 9040.0 |
| RPS9 | 9248.0 |
| RPL3L | 9264.0 |
| RPS24 | 9270.0 |
| COX14 | 9300.0 |
| H2AC14 | 9376.0 |
| HSBP1 | 9397.0 |
| SLC46A1 | 9413.0 |
| RPL18A | 9478.0 |
| CDKN2D | 9489.0 |
| H4C9 | 9492.0 |
| PSMA7 | 9563.0 |
| COX5A | 9635.0 |
| COX6A1 | 9648.0 |
| CCL2 | 9673.0 |
| RLN1 | 9674.0 |
| PSME1 | 9765.0 |
| ERN1 | 9818.0 |
| RPLP2 | 9904.0 |
| H4C12 | 10027.0 |
| RPL7A | 10044.0 |
| CRYAB | 10071.0 |
| SESN2 | 10076.0 |
| ANAPC1 | 10085.0 |
| EXTL1 | 10105.0 |
| MIR24-2 | 10120.0 |
| H2BC14 | 10168.0 |
| ZBTB17 | 10253.0 |
| CAMK2A | 10289.0 |
| RBX1 | 10301.0 |
| GPX8 | 10302.0 |
| ELOB | 10514.0 |
| IL1A | 10585.0 |
| FABP1 | 10587.0 |
| GSTP1 | 10683.0 |
| DDX11 | 10720.0 |
| HSPB2 | 10766.0 |
| MEF2D | 10847.0 |
| PTK6 | 10895.0 |
| CAPZA3 | 10997.0 |
| SCO2 | 11048.0 |
| TUBB8 | 11325.0 |
| GSTA1 | 11431.0 |
REACTOME_MUSCLE_CONTRACTION
| 674 | |
|---|---|
| set | REACTOME_MUSCLE_CONTRACTION |
| setSize | 197 |
| pANOVA | 0.000992 |
| s.dist | 0.136 |
| p.adjustANOVA | 0.0407 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| MYH6 | 11248 |
| SCN11A | 11194 |
| TCAP | 11041 |
| MYL9 | 10913 |
| MYH8 | 10874 |
| MYL10 | 10850 |
| MYL5 | 10604 |
| TNNT3 | 10579 |
| FXYD4 | 10538 |
| ALDH2 | 10448 |
| KCNK6 | 10359 |
| CAMK2A | 10289 |
| KCNK18 | 10270 |
| CASQ1 | 10247 |
| SCN5A | 10232 |
| TRDN | 10181 |
| SCN3A | 10156 |
| TNNI3 | 10036 |
| ITGB5 | 9790 |
| KCNK16 | 9365 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| MYH6 | 11248 |
| SCN11A | 11194 |
| TCAP | 11041 |
| MYL9 | 10913 |
| MYH8 | 10874 |
| MYL10 | 10850 |
| MYL5 | 10604 |
| TNNT3 | 10579 |
| FXYD4 | 10538 |
| ALDH2 | 10448 |
| KCNK6 | 10359 |
| CAMK2A | 10289 |
| KCNK18 | 10270 |
| CASQ1 | 10247 |
| SCN5A | 10232 |
| TRDN | 10181 |
| SCN3A | 10156 |
| TNNI3 | 10036 |
| ITGB5 | 9790 |
| KCNK16 | 9365 |
| KCNJ4 | 9306 |
| ABCC9 | 9261 |
| MYL2 | 9221 |
| CACNA1H | 9061 |
| CAMK2G | 9035 |
| DYSF | 8944 |
| TNNT1 | 8915 |
| FXYD2 | 8754 |
| TNNT2 | 8587 |
| ACTG2 | 8528 |
| ATP1B1 | 8466 |
| CACNA1G | 8448 |
| KCNIP1 | 8277 |
| KCNE2 | 8103 |
| ORAI1 | 7947 |
| SCN4A | 7824 |
| SCN9A | 7779 |
| FXYD7 | 7756 |
| ATP2B2 | 7660 |
| CACNA1C | 7658 |
| PXN | 7555 |
| CASQ2 | 7489 |
| CACNA2D2 | 7485 |
| RYR2 | 7478 |
| SORBS1 | 7407 |
| ATP2A1 | 7381 |
| SCN2B | 7152 |
| ACTN3 | 7106 |
| CACNA1I | 6975 |
| MME | 6825 |
| CACNG7 | 6793 |
| KCNIP4 | 6611 |
| CES1 | 6457 |
| MYL11 | 6416 |
| TNNC2 | 6324 |
| CORIN | 6307 |
| KCNIP3 | 6286 |
| MYBPC3 | 6191 |
| PRKACA | 6168 |
| SCN8A | 6114 |
| FXYD6 | 6101 |
| NOS1 | 6030 |
| MYLK | 6018 |
| KCND2 | 5947 |
| MYL1 | 5937 |
| SCN4B | 5924 |
| KCNE4 | 5818 |
| ATP1B2 | 5792 |
| TRIM72 | 5697 |
| FXYD1 | 5329 |
| MYBPC2 | 5297 |
| MYL4 | 5174 |
| KCNH2 | 5173 |
| CAMK2B | 4977 |
| SCN7A | 4967 |
| KCNJ11 | 4955 |
| ANXA6 | 4858 |
| TPM3 | 4849 |
| ATP1A1 | 4818 |
| KCNQ1 | 4593 |
| SCN1A | 4514 |
| KCNK9 | 4444 |
| SLN | 4318 |
| CALD1 | 4315 |
| KCND3 | 4199 |
| CACNG4 | 4130 |
| TRPC1 | 4118 |
| TMOD1 | 3782 |
| SLC8A1 | 3640 |
| KCNA5 | 3593 |
| TNNI2 | 3500 |
| CACNB2 | 3442 |
| SLC8A3 | 3327 |
| FKBP1B | 3324 |
| SCN1B | 3289 |
| KCNK3 | 3247 |
| ORAI2 | 3191 |
| SCN2A | 3141 |
| KCNK12 | 2912 |
| KCNIP2 | 2829 |
| CAMK2D | 2790 |
| NPR1 | 2595 |
| NPR2 | 2467 |
| KCNE3 | 2266 |
| KCNJ12 | 2083 |
| HIPK2 | 1915 |
| DMPK | 1903 |
| TMOD2 | 1734 |
| FGF14 | 1692 |
| KCNK2 | 1608 |
| ATP2B4 | 1528 |
| SCN10A | 1456 |
| KCNJ14 | 1429 |
| MYL7 | 1426 |
| TPM4 | 1286 |
| ATP1A4 | 1204 |
| PAK1 | 995 |
| MYL6B | 970 |
| WWTR1 | 809 |
| ATP2A3 | 772 |
| ASPH | 702 |
| RYR3 | 577 |
| LMOD1 | 401 |
| ATP1B3 | 172 |
| SLC8A2 | 122 |
| MYL12B | 79 |
| NPPC | -232 |
| VCL | -357 |
| RYR1 | -422 |
| TTN | -680 |
| ACTA2 | -781 |
| GUCY1A2 | -839 |
| TPM2 | -935 |
| KAT2B | -1030 |
| CAV3 | -1219 |
| MYL12A | -1289 |
| VIM | -1328 |
| FXYD3 | -1476 |
| ATP2B1 | -1805 |
| TLN1 | -1936 |
| KCNK15 | -2055 |
| GUCY1A1 | -2118 |
| FGF12 | -2227 |
| KCNK4 | -2245 |
| CALM1 | -2398 |
| CACNB1 | -2451 |
| MYL6 | -2465 |
| DES | -2513 |
| SORBS3 | -2674 |
| MYH11 | -2693 |
| ITPR2 | -2744 |
| MYH3 | -2964 |
| MYBPC1 | -3122 |
| AKAP9 | -3238 |
| TNNI1 | -3373 |
| CACNG8 | -4168 |
| KCNK7 | -4267 |
| TMOD3 | -4428 |
| ITPR1 | -4645 |
| MYL3 | -5076 |
| KCNJ2 | -5206 |
| NPPA | -5260 |
| AHCYL1 | -5337 |
| KCNK17 | -5388 |
| TNNC1 | -5523 |
| HIPK1 | -5542 |
| KCNK10 | -5543 |
| ACTA1 | -5651 |
| KCNK13 | -5656 |
| PDE5A | -5665 |
| ITGA1 | -5867 |
| ANXA2 | -5925 |
| ATP1A3 | -5943 |
| TPM1 | -6088 |
| GATA4 | -6202 |
| KCNK5 | -6294 |
| TBX5 | -6451 |
| NEB | -6489 |
| ATP1A2 | -6604 |
| RANGRF | -6794 |
| ACTN2 | -6817 |
| ITPR3 | -6916 |
| TMOD4 | -6947 |
| SRI | -7351 |
| FGF11 | -7418 |
| PAK2 | -7519 |
| STIM1 | -7699 |
| KCNE1 | -7834 |
| SCN3B | -8184 |
| CACNG6 | -8504 |
| PLN | -8570 |
| ACTC1 | -8583 |
| ANXA1 | -8662 |
| ATP2A2 | -8978 |
| NKX2-5 | -9457 |
| GUCY1B1 | -9610 |
| KCNK1 | -9642 |
REACTOME_SIGNALING_BY_GPCR
| 593 | |
|---|---|
| set | REACTOME_SIGNALING_BY_GPCR |
| setSize | 673 |
| pANOVA | 0.00122 |
| s.dist | 0.0731 |
| p.adjustANOVA | 0.0489 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL1 | 11360 |
| PPBP | 11350 |
| CCL4 | 11339 |
| CCL11 | 11320 |
| ACKR1 | 11272 |
| UCN2 | 11241 |
| CXCR5 | 11212 |
| ADGRE1 | 11184 |
| CCL3 | 11173 |
| LPAR5 | 11137 |
| CXCR1 | 11124 |
| CCL16 | 10983 |
| KEL | 10982 |
| GNGT1 | 10937 |
| SAA1 | 10931 |
| ACKR2 | 10882 |
| ADRA2B | 10860 |
| GALR3 | 10857 |
| C5AR2 | 10840 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CCL5 | 11398 |
| CCL1 | 11360 |
| PPBP | 11350 |
| CCL4 | 11339 |
| CCL11 | 11320 |
| ACKR1 | 11272 |
| UCN2 | 11241 |
| CXCR5 | 11212 |
| ADGRE1 | 11184 |
| CCL3 | 11173 |
| LPAR5 | 11137 |
| CXCR1 | 11124 |
| CCL16 | 10983 |
| KEL | 10982 |
| GNGT1 | 10937 |
| SAA1 | 10931 |
| ACKR2 | 10882 |
| ADRA2B | 10860 |
| GALR3 | 10857 |
| C5AR2 | 10840 |
| GNG8 | 10795 |
| NTS | 10777 |
| CCL13 | 10670 |
| GHRHR | 10616 |
| CCR7 | 10612 |
| PTGIR | 10599 |
| NPW | 10593 |
| BDKRB1 | 10569 |
| GHRH | 10550 |
| GIP | 10547 |
| GPR20 | 10526 |
| P2RY2 | 10520 |
| TAS1R3 | 10502 |
| WNT9A | 10483 |
| HCAR2 | 10444 |
| IAPP | 10421 |
| APLNR | 10416 |
| P2RY11 | 10408 |
| WNT4 | 10390 |
| UCN3 | 10368 |
| PRKAR2A | 10361 |
| CAMK2A | 10289 |
| CCL19 | 10278 |
| DGKQ | 10248 |
| CMKLR1 | 10241 |
| NPB | 10240 |
| TAS2R46 | 10225 |
| FZD4 | 10209 |
| FSHR | 10204 |
| HCAR1 | 10183 |
| CX3CR1 | 10142 |
| FFAR1 | 10138 |
| PPP1CA | 10127 |
| RGS2 | 10125 |
| DGKB | 10112 |
| PREX1 | 10060 |
| GPR35 | 10033 |
| TAS2R16 | 10005 |
| SCTR | 9946 |
| TAS2R41 | 9937 |
| INSL3 | 9912 |
| CCR2 | 9871 |
| GNA15 | 9779 |
| MMP3 | 9749 |
| INSL5 | 9676 |
| CCL2 | 9673 |
| GAST | 9564 |
| PROK1 | 9532 |
| SUCNR1 | 9522 |
| CXCR6 | 9514 |
| WNT9B | 9506 |
| PTAFR | 9482 |
| ARHGEF19 | 9451 |
| GNG13 | 9443 |
| GNB3 | 9437 |
| NPY | 9433 |
| PTH | 9412 |
| GNAT1 | 9398 |
| CCL25 | 9393 |
| CXCL12 | 9321 |
| P2RY6 | 9308 |
| CCR5 | 9293 |
| ADGRE5 | 9274 |
| ARHGEF2 | 9263 |
| ADCY5 | 9251 |
| MCHR1 | 9187 |
| ADRA2C | 9171 |
| LTB4R2 | 9148 |
| GNAI2 | 9127 |
| TAAR5 | 9071 |
| NPS | 9053 |
| GPR84 | 9045 |
| CAMK2G | 9035 |
| CCRL2 | 9032 |
| TAS2R38 | 9027 |
| CCL17 | 8999 |
| ARHGEF10L | 8994 |
| CHRM1 | 8975 |
| RAMP3 | 8938 |
| RGS1 | 8925 |
| NPFFR1 | 8889 |
| ARHGEF11 | 8876 |
| GRB2 | 8831 |
| PLA2G4A | 8803 |
| PF4 | 8801 |
| WNT11 | 8790 |
| GNA14 | 8773 |
| RGSL1 | 8764 |
| LHCGR | 8760 |
| ADGRE2 | 8759 |
| LTB4R | 8733 |
| MLN | 8723 |
| CCL22 | 8716 |
| PIK3R6 | 8699 |
| CXCL8 | 8674 |
| TRPC7 | 8619 |
| PDE2A | 8571 |
| GPR17 | 8569 |
| KISS1 | 8474 |
| TACR2 | 8456 |
| GPR45 | 8409 |
| TAS1R2 | 8362 |
| TAS2R1 | 8330 |
| GPR150 | 8262 |
| GNRH2 | 8237 |
| AVPR1B | 8230 |
| CCL7 | 8148 |
| ARHGEF3 | 8137 |
| GCG | 8119 |
| GPR37L1 | 8118 |
| CHRM3 | 8117 |
| GRM4 | 8116 |
| GNGT2 | 8088 |
| TAS1R1 | 8083 |
| RGS13 | 8072 |
| UTS2B | 8040 |
| GABBR2 | 8033 |
| LPAR1 | 8022 |
| GRK2 | 8010 |
| ARHGEF38 | 7988 |
| MGLL | 7964 |
| PLEKHG2 | 7921 |
| HRH1 | 7916 |
| ADM2 | 7914 |
| PDYN | 7858 |
| RHOA | 7838 |
| KISS1R | 7801 |
| MC5R | 7784 |
| FN1 | 7701 |
| AGTR1 | 7659 |
| GPRC6A | 7580 |
| XCL1 | 7569 |
| TAS2R42 | 7462 |
| TAS2R14 | 7427 |
| CXCL13 | 7402 |
| GNAQ | 7390 |
| HRAS | 7386 |
| GNRHR | 7288 |
| HTR7 | 7274 |
| ADCYAP1R1 | 7263 |
| NPBWR2 | 7250 |
| OXGR1 | 7249 |
| FPR1 | 7228 |
| GPR132 | 7165 |
| DAGLA | 7163 |
| VIP | 7127 |
| PPP3CC | 7103 |
| PRKCD | 7089 |
| CX3CL1 | 7075 |
| TRHR | 7074 |
| ADCY6 | 7056 |
| WNT1 | 6979 |
| CCL27 | 6904 |
| TAC3 | 6886 |
| PLCB4 | 6885 |
| GPR183 | 6871 |
| HBEGF | 6870 |
| DGKI | 6783 |
| PPP2R5D | 6733 |
| GNG5 | 6619 |
| RGS8 | 6612 |
| SRC | 6605 |
| C5AR1 | 6604 |
| DRD2 | 6571 |
| HCRTR1 | 6546 |
| GPR31 | 6534 |
| GPR55 | 6530 |
| TAS2R9 | 6517 |
| PDE1A | 6456 |
| KALRN | 6449 |
| GNAZ | 6382 |
| NPSR1 | 6381 |
| CNR2 | 6311 |
| FFAR2 | 6245 |
| TAS2R19 | 6181 |
| PRKACA | 6168 |
| TSHB | 6153 |
| RGS3 | 6138 |
| ARHGEF16 | 6129 |
| GRK6 | 6044 |
| S1PR4 | 5970 |
| PYY | 5963 |
| ARHGEF17 | 5906 |
| GPR176 | 5892 |
| GNA13 | 5876 |
| CCR6 | 5675 |
| GPR39 | 5621 |
| CALCA | 5596 |
| OXER1 | 5521 |
| PDE8A | 5512 |
| PLXNB1 | 5425 |
| DGKE | 5418 |
| PSAP | 5411 |
| HTR6 | 5397 |
| TAS2R40 | 5383 |
| GNG4 | 5377 |
| SSTR5 | 5345 |
| RAMP2 | 5341 |
| ADRA1B | 5263 |
| PTH1R | 5259 |
| GRM2 | 5255 |
| GLP1R | 5200 |
| ARHGEF37 | 5190 |
| EDNRA | 5183 |
| OPN5 | 5094 |
| GPR4 | 5075 |
| HTR2B | 5004 |
| VAV2 | 5001 |
| CAMK2B | 4977 |
| FZD5 | 4974 |
| RGS18 | 4966 |
| SSTR2 | 4960 |
| NPY2R | 4914 |
| ADCY1 | 4852 |
| RLN3 | 4808 |
| GPSM1 | 4752 |
| VAV1 | 4726 |
| ROCK1 | 4717 |
| S1PR3 | 4702 |
| MCHR2 | 4685 |
| AKT1 | 4674 |
| ADORA1 | 4668 |
| PDE4B | 4645 |
| SOS2 | 4575 |
| PPP3CB | 4557 |
| PRKCE | 4545 |
| PROKR2 | 4535 |
| GRM5 | 4512 |
| EGFR | 4497 |
| PDE4D | 4488 |
| PPP2R1A | 4431 |
| PPP2CA | 4421 |
| FZD1 | 4396 |
| RGS12 | 4395 |
| PTGER4 | 4394 |
| GPR15 | 4383 |
| GNA11 | 4327 |
| ADRB2 | 4307 |
| NPFFR2 | 4241 |
| RGS19 | 4196 |
| GPHB5 | 4195 |
| PPP3R1 | 4121 |
| OPRL1 | 4114 |
| ABHD12 | 4085 |
| PRKAR2B | 4071 |
| GPR25 | 4029 |
| TAS2R43 | 4016 |
| PTH2R | 3945 |
| GRM8 | 3907 |
| PIK3CA | 3848 |
| GNG7 | 3838 |
| CALCRL | 3833 |
| PIK3CG | 3809 |
| RXFP1 | 3761 |
| PLCB3 | 3721 |
| RGS6 | 3664 |
| CXCL9 | 3663 |
| AVP | 3646 |
| HTR4 | 3548 |
| RGR | 3508 |
| OPN4 | 3438 |
| PDE3B | 3418 |
| PPP2CB | 3417 |
| ADCY8 | 3376 |
| FZD7 | 3358 |
| MCF2L | 3259 |
| TACR1 | 3240 |
| PPP1R1B | 3234 |
| PIK3R3 | 3156 |
| C5 | 3121 |
| PIK3R5 | 3066 |
| ARRB1 | 3054 |
| PRKAR1A | 3042 |
| SMO | 2979 |
| PNOC | 2950 |
| ADCY9 | 2936 |
| MTNR1B | 2930 |
| GRK3 | 2878 |
| DHH | 2842 |
| CAMK2D | 2790 |
| GRM1 | 2773 |
| NTSR1 | 2761 |
| CHRM5 | 2733 |
| PLPPR3 | 2705 |
| ADCY3 | 2673 |
| CNR1 | 2666 |
| OXTR | 2650 |
| CCK | 2646 |
| PROKR1 | 2635 |
| PIK3R2 | 2617 |
| TAS2R8 | 2612 |
| HRH4 | 2609 |
| FZD3 | 2590 |
| GRM7 | 2543 |
| FZD2 | 2477 |
| TAS2R60 | 2469 |
| PLEKHG5 | 2451 |
| TAAR1 | 2446 |
| MAPK3 | 2444 |
| EDN2 | 2437 |
| SSTR3 | 2424 |
| C3 | 2422 |
| WNT3 | 2405 |
| RGS7 | 2402 |
| GRM3 | 2358 |
| WNT8A | 2351 |
| ECT2 | 2291 |
| PTGER1 | 2286 |
| RGS20 | 2255 |
| WNT7A | 2232 |
| RGS22 | 2177 |
| HTR2A | 2136 |
| RPS6KA1 | 2135 |
| RGS16 | 2131 |
| ITGB1 | 2081 |
| PDE11A | 2059 |
| CDK5 | 2048 |
| CAMKK1 | 2006 |
| CCKBR | 2005 |
| GLP2R | 2002 |
| SHC1 | 1868 |
| RAMP1 | 1857 |
| RHO | 1851 |
| ADCY4 | 1849 |
| GABBR1 | 1836 |
| CAMKK2 | 1817 |
| CCL20 | 1795 |
| PDE8B | 1779 |
| HRH3 | 1765 |
| RGS11 | 1764 |
| TIAM1 | 1735 |
| ARHGEF1 | 1727 |
| PDE1B | 1714 |
| CDC42 | 1603 |
| FGD4 | 1571 |
| BDKRB2 | 1546 |
| CXCL11 | 1494 |
| UTS2R | 1472 |
| DGKG | 1443 |
| WNT5A | 1441 |
| RGS17 | 1431 |
| ADCY2 | 1392 |
| WNT7B | 1285 |
| GRP | 1246 |
| WNT2B | 1171 |
| KNG1 | 1101 |
| PDE10A | 1084 |
| DRD1 | 1050 |
| HTR1D | 1019 |
| PRKCH | 1006 |
| PAK1 | 995 |
| HTR1E | 953 |
| NRAS | 939 |
| GNG2 | 908 |
| AKAP13 | 798 |
| PDE4C | 788 |
| NMB | 711 |
| CCR8 | 698 |
| PTGER3 | 657 |
| HCRTR2 | 650 |
| RASGRP2 | 626 |
| TAS2R13 | 622 |
| NGEF | 615 |
| WNT16 | 597 |
| EDN3 | 582 |
| NMUR1 | 527 |
| ROCK2 | 474 |
| VIPR1 | 446 |
| CREB1 | 391 |
| NMS | 387 |
| CXCL16 | 278 |
| ITGA5 | 225 |
| GNAL | 213 |
| ARHGEF15 | 144 |
| GNG11 | 104 |
| TIAM2 | 87 |
| MAPK1 | 78 |
| GNAI1 | 77 |
| RGS14 | 76 |
| GNAT2 | -30 |
| PLCB1 | -150 |
| TBXA2R | -197 |
| F2RL3 | -206 |
| ADORA2B | -210 |
| FGD2 | -219 |
| WNT10B | -288 |
| ARHGEF40 | -306 |
| DGKZ | -309 |
| ECE2 | -315 |
| ECE1 | -317 |
| ABR | -321 |
| CXCL1 | -394 |
| ARHGEF12 | -402 |
| GNG12 | -413 |
| PLPPR1 | -432 |
| VAV3 | -474 |
| PDE7B | -497 |
| NPFF | -523 |
| GNAT3 | -540 |
| MLNR | -585 |
| GPR18 | -614 |
| FPR3 | -617 |
| FPR2 | -666 |
| ARHGEF25 | -708 |
| ARHGEF18 | -822 |
| PTHLH | -834 |
| CCL28 | -937 |
| OXT | -949 |
| POMC | -950 |
| GNG3 | -991 |
| PRKCA | -1066 |
| S1PR2 | -1114 |
| OPRM1 | -1202 |
| NMBR | -1212 |
| MAPK7 | -1222 |
| RPS6KA2 | -1273 |
| ADRA1A | -1346 |
| GPSM2 | -1356 |
| GHRL | -1371 |
| SST | -1395 |
| PTCH2 | -1500 |
| ADRB1 | -1514 |
| F2 | -1609 |
| FFAR4 | -1612 |
| TAAR9 | -1688 |
| PDE4A | -1783 |
| NMU | -1787 |
| ARHGEF39 | -1820 |
| ITSN1 | -1913 |
| TRIO | -1915 |
| PDE7A | -1923 |
| CALCR | -2014 |
| TAS2R39 | -2086 |
| HTR5A | -2091 |
| CCR1 | -2124 |
| ARHGEF26 | -2211 |
| ARHGEF10 | -2334 |
| GPR37 | -2351 |
| PRLH | -2360 |
| ADM | -2376 |
| CALM1 | -2398 |
| P2RY12 | -2439 |
| GNB2 | -2516 |
| GRK5 | -2623 |
| GNG10 | -2641 |
| PRKCQ | -2709 |
| OBSCN | -2720 |
| ITPR2 | -2744 |
| PDE1C | -2783 |
| CRHR1 | -2857 |
| PROK2 | -2892 |
| KRAS | -2902 |
| OPN3 | -2907 |
| PTCH1 | -2913 |
| SSTR4 | -2930 |
| GNB1 | -3044 |
| ADCY7 | -3144 |
| ARHGEF4 | -3205 |
| GIPR | -3214 |
| NTSR2 | -3289 |
| CCL23 | -3306 |
| GPER1 | -3375 |
| WNT10A | -3378 |
| CRHBP | -3418 |
| CXCL2 | -3545 |
| ADORA3 | -3560 |
| NBEA | -3794 |
| XCL2 | -3802 |
| EDNRB | -3877 |
| CAMK4 | -3886 |
| RGS10 | -3927 |
| RHOC | -3974 |
| CRHR2 | -3983 |
| GNB5 | -4000 |
| WNT3A | -4013 |
| RGS5 | -4033 |
| RRH | -4034 |
| PCP2 | -4145 |
| GPR32 | -4157 |
| OPRK1 | -4205 |
| PDPK1 | -4223 |
| MC2R | -4327 |
| TSHR | -4380 |
| RGS9 | -4406 |
| GNA12 | -4424 |
| PIK3R1 | -4455 |
| RASGRP1 | -4456 |
| TAS2R7 | -4498 |
| ADRB3 | -4544 |
| CXCR4 | -4639 |
| ITPR1 | -4645 |
| NPBWR1 | -4727 |
| IHH | -4808 |
| CASR | -4829 |
| CXCL6 | -4832 |
| PLCB2 | -4847 |
| ARHGEF33 | -4873 |
| PRKCB | -4898 |
| P2RY1 | -4992 |
| VIPR2 | -5003 |
| CD55 | -5091 |
| XCR1 | -5197 |
| NPY5R | -5210 |
| P2RY14 | -5221 |
| GHSR | -5248 |
| SOS1 | -5251 |
| GNAI3 | -5261 |
| AHCYL1 | -5337 |
| AKT2 | -5419 |
| CRH | -5434 |
| RXFP2 | -5452 |
| NPY1R | -5478 |
| CGA | -5492 |
| RGS4 | -5531 |
| RGS21 | -5583 |
| CORT | -5586 |
| RLN2 | -5597 |
| KPNA2 | -5599 |
| FZD6 | -5601 |
| CCR10 | -5602 |
| DGKH | -5640 |
| AKT3 | -5680 |
| GRM6 | -5717 |
| LPAR6 | -5738 |
| TAS2R20 | -5840 |
| PDE3A | -5865 |
| CALCB | -5954 |
| TAAR6 | -6003 |
| PPP3CA | -6118 |
| NMUR2 | -6166 |
| DRD3 | -6201 |
| CCL21 | -6205 |
| TRPC3 | -6233 |
| WNT8B | -6250 |
| GPR68 | -6321 |
| RXFP4 | -6337 |
| TAAR2 | -6348 |
| CXCR2 | -6351 |
| PTH2 | -6406 |
| LPAR2 | -6445 |
| ARRB2 | -6501 |
| GNB4 | -6570 |
| SHH | -6591 |
| PRKCG | -6643 |
| LPAR3 | -6667 |
| TAS2R5 | -6695 |
| PLPPR4 | -6731 |
| CYSLTR2 | -6777 |
| FZD9 | -6800 |
| TAS2R3 | -6822 |
| GPR65 | -6907 |
| ITPR3 | -6916 |
| P2RY13 | -6943 |
| FGD3 | -6957 |
| PTGDR2 | -6976 |
| GPSM3 | -7016 |
| S1PR1 | -7057 |
| HEBP1 | -7112 |
| TACR3 | -7128 |
| CXCL10 | -7168 |
| CHRM2 | -7218 |
| ABHD6 | -7261 |
| AVPR1A | -7294 |
| HTR1F | -7316 |
| TAS2R30 | -7323 |
| FZD10 | -7382 |
| NET1 | -7396 |
| OPRD1 | -7433 |
| CXCL3 | -7445 |
| PRKAR1B | -7460 |
| ARHGEF7 | -7560 |
| GALR2 | -7605 |
| CCR3 | -7619 |
| MC3R | -7629 |
| SSTR1 | -7706 |
| PLPPR5 | -7712 |
| HRH2 | -7797 |
| PLPPR2 | -7801 |
| PRKACB | -7806 |
| WNT6 | -7852 |
| RHOB | -7863 |
| C3AR1 | -7923 |
| PPY | -7938 |
| ADORA2A | -7940 |
| HCRT | -8028 |
| RASGRF2 | -8039 |
| WNT2 | -8072 |
| FZD8 | -8078 |
| NLN | -8089 |
| APP | -8179 |
| TRH | -8189 |
| DAGLB | -8191 |
| PTGFR | -8203 |
| TRPC6 | -8219 |
| ADRA1D | -8226 |
| AGT | -8244 |
| DGKD | -8259 |
| S1PR5 | -8273 |
| DRD5 | -8329 |
| DGKA | -8349 |
| TAS2R10 | -8397 |
| GPR27 | -8403 |
| ADRA2A | -8477 |
| MTNR1A | -8519 |
| UTS2 | -8541 |
| MC4R | -8625 |
| ACKR3 | -8628 |
| F2R | -8654 |
| ANXA1 | -8662 |
| FFAR3 | -8710 |
| SCT | -8750 |
| RXFP3 | -8766 |
| FSHB | -8940 |
| GNRH1 | -8953 |
| CCR9 | -9041 |
| TAC1 | -9075 |
| EDN1 | -9092 |
| CHRM4 | -9142 |
| F2RL2 | -9191 |
| TAS2R31 | -9210 |
| TAS2R50 | -9218 |
| HTR1A | -9219 |
| PENK | -9233 |
| PPP2R1B | -9252 |
| OPN1SW | -9449 |
| MC1R | -9473 |
| QRFPR | -9504 |
| CCR4 | -9527 |
| PRKACG | -9541 |
| GPHA2 | -9552 |
| F2RL1 | -9594 |
| GPR83 | -9632 |
| ADCYAP1 | -9638 |
| GAL | -9665 |
| PRLHR | -9669 |
| HTR1B | -9681 |
| PTGER2 | -9690 |
| GNAS | -9712 |
| CCKAR | -9806 |
| CXCL5 | -9848 |
| PTGDR | -9930 |
| DRD4 | -9935 |
| GPBAR1 | -9956 |
| LHB | -10018 |
| ADGRE3 | -10051 |
| TAS2R4 | -10102 |
| TAAR8 | -10105 |
| UCN | -10152 |
| ARHGEF5 | -10231 |
| GALR1 | -10232 |
| PMCH | -10265 |
| QRFP | -10370 |
| ACKR4 | -10417 |
REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC
| 1087 | |
|---|---|
| set | REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC |
| setSize | 198 |
| pANOVA | 0.00129 |
| s.dist | -0.133 |
| p.adjustANOVA | 0.0497 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| KIF12 | -9319 |
| TUBB4B | -9023 |
| COG5 | -8916 |
| TUBA1C | -8675 |
| COG6 | -8613 |
| GOLGA5 | -8607 |
| TUBA3E | -8293 |
| GBF1 | -8249 |
| RAB3GAP1 | -8241 |
| KIF22 | -8130 |
| VPS51 | -7635 |
| M6PR | -7626 |
| STX16 | -7512 |
| DYNLL2 | -7477 |
| GOLGA4 | -7375 |
| KIF2C | -7337 |
| NAA30 | -7054 |
| KIF20B | -7039 |
| NBAS | -6801 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| KIF12 | -9319 |
| TUBB4B | -9023 |
| COG5 | -8916 |
| TUBA1C | -8675 |
| COG6 | -8613 |
| GOLGA5 | -8607 |
| TUBA3E | -8293 |
| GBF1 | -8249 |
| RAB3GAP1 | -8241 |
| KIF22 | -8130 |
| VPS51 | -7635 |
| M6PR | -7626 |
| STX16 | -7512 |
| DYNLL2 | -7477 |
| GOLGA4 | -7375 |
| KIF2C | -7337 |
| NAA30 | -7054 |
| KIF20B | -7039 |
| NBAS | -6801 |
| KIF11 | -6773 |
| NAPG | -6750 |
| TUBA4A | -6626 |
| MAN2A2 | -6624 |
| DCTN3 | -6556 |
| RAB18 | -6554 |
| IGF2R | -6515 |
| DYNC1H1 | -6464 |
| TUBB2B | -6314 |
| SNAP29 | -6260 |
| KLC2 | -6094 |
| KIF21A | -6087 |
| ZW10 | -6072 |
| COPG2 | -6052 |
| TUBB2A | -5979 |
| RABEPK | -5901 |
| COG8 | -5869 |
| KIF1B | -5751 |
| ARF5 | -5690 |
| KIF18B | -5555 |
| VPS54 | -5484 |
| NAA35 | -5382 |
| VPS52 | -5352 |
| KDELR2 | -5282 |
| RINT1 | -5239 |
| TMED2 | -5231 |
| DYNC1I2 | -5131 |
| SEC22B | -5075 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| BICD1 | -4885 |
| NAPB | -4763 |
| KIFC1 | -4760 |
| DYNC1LI2 | -4730 |
| ARFGAP2 | -4644 |
| KIF26A | -4640 |
| KIF2A | -4638 |
| TUBA1B | -4624 |
| TMF1 | -4557 |
| ACTR10 | -4445 |
| ARCN1 | -4315 |
| COG2 | -4301 |
| PLA2G6 | -4289 |
| VTI1A | -4268 |
| CAPZB | -4153 |
| TRIP11 | -4089 |
| TUBA8 | -4032 |
| GOSR2 | -4003 |
| USE1 | -3970 |
| VAMP3 | -3960 |
| COPE | -3943 |
| DCTN4 | -3874 |
| CYTH3 | -3850 |
| NSF | -3605 |
| VPS53 | -3575 |
| KDELR3 | -3573 |
| DYNLL1 | -3550 |
| COG3 | -3267 |
| TMED10 | -3046 |
| RAB3GAP2 | -2923 |
| RAB43 | -2891 |
| COPA | -2869 |
| KIF21B | -2694 |
| RAB33B | -2691 |
| PAFAH1B1 | -2571 |
| ARF3 | -2554 |
| GALNT2 | -2528 |
| KIF25 | -2426 |
| RHOBTB3 | -2422 |
| MAN1C1 | -2399 |
| DYNC1I1 | -2088 |
| AGPAT3 | -2075 |
| ARFIP2 | -2073 |
| ARF4 | -1971 |
| COG7 | -1922 |
| TUBA1A | -1819 |
| KIF15 | -1735 |
| GOLIM4 | -1598 |
| KIF13B | -1565 |
| SYS1 | -1543 |
| KLC1 | -1158 |
| KIFAP3 | -1087 |
| STX5 | -1070 |
| RAB6A | -743 |
| GCC2 | -689 |
| RIC1 | -526 |
| NAPA | -484 |
| COPZ1 | -343 |
| DCTN1 | -338 |
| GOSR1 | -79 |
| KIF1C | -62 |
| KIF2B | -57 |
| ALPP | 34 |
| STX6 | 197 |
| COPB1 | 335 |
| CYTH4 | 346 |
| MAN1A2 | 412 |
| KIF3C | 440 |
| KIF3B | 591 |
| CAPZA1 | 768 |
| RAB1B | 777 |
| KIF5B | 952 |
| KIF18A | 960 |
| TMED9 | 966 |
| CAPZA2 | 982 |
| TUBB1 | 1069 |
| KIF20A | 1088 |
| COG4 | 1128 |
| STX18 | 1179 |
| TMED3 | 1216 |
| STX10 | 1296 |
| GOLGA1 | 1356 |
| MAN2A1 | 1375 |
| ARF1 | 1430 |
| USP6NL | 1563 |
| RAB36 | 1635 |
| RGP1 | 1693 |
| VPS45 | 1762 |
| COG1 | 1790 |
| KIF27 | 2200 |
| ACTR1A | 2220 |
| CENPE | 2236 |
| KIF26B | 2331 |
| KIF3A | 2489 |
| SURF4 | 2502 |
| TMED7 | 2537 |
| PAFAH1B3 | 2557 |
| ARL1 | 2630 |
| COPZ2 | 2659 |
| MAN1A1 | 2898 |
| ARFGAP3 | 3056 |
| TUBA3C | 3214 |
| BNIP1 | 3291 |
| KIF1A | 3462 |
| CUX1 | 3472 |
| GALNT1 | 3535 |
| TUBB6 | 3539 |
| TUBB4A | 3612 |
| NAA38 | 3629 |
| ARFGAP1 | 3928 |
| VAMP4 | 3956 |
| PAFAH1B2 | 3999 |
| KIF6 | 4207 |
| KLC4 | 4410 |
| COPB2 | 4499 |
| RAB1A | 4669 |
| RAB30 | 4747 |
| RACGAP1 | 4800 |
| COPG1 | 4917 |
| BICD2 | 4919 |
| DCTN6 | 4994 |
| GCC1 | 5230 |
| KLC3 | 5399 |
| YKT6 | 5640 |
| ARFRP1 | 5848 |
| KIF5A | 5983 |
| RAB39A | 6205 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| CYTH1 | 6315 |
| KIF19 | 6394 |
| TGOLN2 | 6481 |
| RAB6B | 6569 |
| KDELR1 | 6652 |
| DYNC1LI1 | 6830 |
| KIF16B | 6957 |
| PLIN3 | 7229 |
| KIF4B | 7363 |
| DCTN5 | 7453 |
| SCOC | 7771 |
| CYTH2 | 7855 |
| KIFC2 | 7972 |
| KIF9 | 8184 |
| BET1L | 8253 |
| PLA2G4A | 8803 |
| KIF23 | 8961 |
| CAPZA3 | 10997 |
| TUBB8 | 11325 |
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR
| 1008 | |
|---|---|
| set | REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR |
| setSize | 162 |
| pANOVA | 0.0013 |
| s.dist | -0.146 |
| p.adjustANOVA | 0.0497 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TIMELESS | -9871.0 |
| CHEK1 | -9546.0 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| PALB2 | -8722.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| NSD2 | -8330.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| XRCC2 | -8091.0 |
| ABRAXAS1 | -7840.0 |
| H2BC5 | -7799.0 |
| RPA1 | -7755.0 |
| POLE | -7738.0 |
| H2AX | -7648.0 |
| TDP1 | -7576.0 |
| TOPBP1 | -7459.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TIMELESS | -9871.0 |
| CHEK1 | -9546.0 |
| H2BC7 | -9424.5 |
| SUMO2 | -9418.0 |
| RHNO1 | -8854.0 |
| HERC2 | -8765.0 |
| PALB2 | -8722.0 |
| H4C13 | -8603.0 |
| RBBP8 | -8595.0 |
| NSD2 | -8330.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| XRCC2 | -8091.0 |
| ABRAXAS1 | -7840.0 |
| H2BC5 | -7799.0 |
| RPA1 | -7755.0 |
| POLE | -7738.0 |
| H2AX | -7648.0 |
| TDP1 | -7576.0 |
| TOPBP1 | -7459.0 |
| POLE2 | -7447.0 |
| BRCA2 | -7322.0 |
| POLH | -7122.0 |
| POLD2 | -7092.0 |
| SIRT6 | -7060.0 |
| XRCC6 | -6924.0 |
| ABL1 | -6881.0 |
| SMARCA5 | -6825.0 |
| RIF1 | -6761.0 |
| TOP3A | -6676.0 |
| RFC1 | -6662.0 |
| XRCC4 | -6593.0 |
| H2BC10 | -6510.0 |
| BARD1 | -6508.0 |
| PRKDC | -6492.0 |
| BRCA1 | -6477.0 |
| PAXIP1 | -6327.0 |
| POLK | -6296.0 |
| GEN1 | -6109.0 |
| POLQ | -5875.0 |
| H2BC15 | -5694.0 |
| RNF168 | -5628.0 |
| KPNA2 | -5599.0 |
| H3-4 | -5447.0 |
| H2BC6 | -5295.0 |
| KDM4A | -5242.0 |
| ATM | -5218.0 |
| H2BC4 | -5066.0 |
| UBE2V2 | -4803.0 |
| RAD51D | -4706.0 |
| RFC5 | -4673.0 |
| H4C6 | -4534.0 |
| RAD1 | -4483.0 |
| PARP2 | -4469.0 |
| RNF8 | -4361.0 |
| H2BC9 | -4255.5 |
| H2BC17 | -4192.0 |
| WRN | -4104.0 |
| RAD50 | -4035.0 |
| H4C4 | -3867.0 |
| POLD1 | -3772.0 |
| XRCC1 | -3716.0 |
| H2BC26 | -3582.0 |
| PPP4R2 | -3563.0 |
| LIG4 | -3340.0 |
| ERCC4 | -3260.0 |
| APBB1 | -3255.0 |
| BAP1 | -3166.0 |
| HUS1 | -3130.0 |
| EYA4 | -2880.0 |
| RAD51B | -2519.0 |
| CCNA1 | -2494.0 |
| H4C11 | -2488.0 |
| POLM | -2326.0 |
| BABAM1 | -2123.0 |
| CLSPN | -2005.0 |
| KAT5 | -1955.0 |
| BAZ1B | -1790.0 |
| KDM4B | -1738.0 |
| ATR | -1677.0 |
| DCLRE1C | -1428.0 |
| POLE3 | -1337.0 |
| SLX4 | -1316.0 |
| POLD3 | -1246.0 |
| RMI1 | -1065.0 |
| H2BC8 | -1029.0 |
| PPP4C | -965.0 |
| ATRIP | -702.0 |
| TP53 | -548.0 |
| RAD17 | -530.0 |
| XRCC5 | -495.0 |
| PARP1 | -295.0 |
| RAD52 | -229.0 |
| UBA52 | -167.0 |
| MDC1 | -145.0 |
| PCNA | -40.0 |
| DNA2 | -36.0 |
| PPP5C | -20.0 |
| RFC3 | -16.0 |
| SPIDR | 112.0 |
| MAPK8 | 364.0 |
| H4C5 | 878.0 |
| RAD51 | 905.0 |
| RFC4 | 973.0 |
| BABAM2 | 1018.0 |
| RPA2 | 1210.0 |
| POLL | 1222.0 |
| NHEJ1 | 1484.0 |
| SEM1 | 1794.0 |
| RPS27A | 1846.0 |
| H2BC3 | 1920.0 |
| SUMO1 | 2052.0 |
| RAD51C | 2354.0 |
| EXO1 | 2396.0 |
| MUS81 | 2574.0 |
| H2BC1 | 2755.0 |
| FEN1 | 2933.0 |
| BRIP1 | 3028.0 |
| TP53BP1 | 3107.0 |
| EYA1 | 3139.0 |
| RTEL1 | 3221.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| RMI2 | 3423.0 |
| UIMC1 | 3452.0 |
| NBN | 3478.0 |
| PIAS4 | 3685.0 |
| TIPIN | 3874.0 |
| BLM | 3894.0 |
| RFC2 | 4313.0 |
| CCNA2 | 4366.0 |
| RPA3 | 4481.0 |
| EYA3 | 4781.0 |
| UBE2N | 4905.0 |
| UBXN1 | 4957.0 |
| H4C3 | 5053.0 |
| CDK2 | 5165.0 |
| EME1 | 5291.0 |
| EME2 | 5376.0 |
| MRE11 | 5531.0 |
| RAD9A | 5759.0 |
| POLD4 | 6046.0 |
| RNF4 | 6134.0 |
| XRCC3 | 6155.0 |
| H2BC11 | 6454.0 |
| UBC | 6700.0 |
| RAD9B | 6859.0 |
| EYA2 | 7010.0 |
| UBE2I | 7189.0 |
| H2BC21 | 7408.0 |
| CHEK2 | 7446.0 |
| RAD51AP1 | 7593.0 |
| UBB | 7594.0 |
| H2BC12 | 7676.0 |
| TDP2 | 7875.0 |
| ERCC1 | 8264.0 |
| POLE4 | 8577.0 |
| H4C1 | 8782.0 |
| H4C9 | 9492.0 |
| H4C12 | 10027.0 |
| LIG3 | 10147.0 |
| H2BC14 | 10168.0 |
REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS
| 901 | |
|---|---|
| set | REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS |
| setSize | 113 |
| pANOVA | 0.00152 |
| s.dist | -0.173 |
| p.adjustANOVA | 0.0567 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CNOT6 | -9599.0 |
| YY1 | -9556.0 |
| HOXD1 | -9470.0 |
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| H3C4 | -9267.0 |
| MEIS1 | -9204.0 |
| HOXA4 | -9120.0 |
| HOXD3 | -8970.0 |
| PAX6 | -8886.0 |
| SUZ12 | -8683.0 |
| H4C13 | -8603.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| ASH2L | -8064.0 |
| KMT2C | -7976.0 |
| H2BC5 | -7799.0 |
| CNOT9 | -7665.0 |
| H2AX | -7648.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CNOT6 | -9599.0 |
| YY1 | -9556.0 |
| HOXD1 | -9470.0 |
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| H3C4 | -9267.0 |
| MEIS1 | -9204.0 |
| HOXA4 | -9120.0 |
| HOXD3 | -8970.0 |
| PAX6 | -8886.0 |
| SUZ12 | -8683.0 |
| H4C13 | -8603.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| ASH2L | -8064.0 |
| KMT2C | -7976.0 |
| H2BC5 | -7799.0 |
| CNOT9 | -7665.0 |
| H2AX | -7648.0 |
| POLR2A | -7443.0 |
| H3C6 | -7372.0 |
| HOXA2 | -7371.0 |
| NCOA6 | -7292.0 |
| HOXA1 | -7191.0 |
| EP300 | -7126.0 |
| HOXC4 | -6896.0 |
| HOXB3 | -6724.0 |
| H2BC10 | -6510.0 |
| POLR2K | -6386.0 |
| PAXIP1 | -6327.0 |
| HOXB1 | -6305.0 |
| HOXD4 | -5960.0 |
| H2AC6 | -5775.0 |
| RBBP5 | -5722.0 |
| WDR5 | -5702.0 |
| H2BC15 | -5694.0 |
| H3C11 | -5538.0 |
| H2BC6 | -5295.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| AJUBA | -4908.0 |
| EED | -4626.0 |
| POLR2J | -4576.0 |
| H4C6 | -4534.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| H2BC17 | -4192.0 |
| POLR2B | -4142.0 |
| H4C4 | -3867.0 |
| H2AJ | -3814.0 |
| H2BC26 | -3582.0 |
| KMT2D | -3430.0 |
| CREBBP | -3271.0 |
| HOXB4 | -2899.0 |
| H4C11 | -2488.0 |
| PCGF2 | -2415.0 |
| HDAC3 | -1872.0 |
| H3C10 | -1789.0 |
| H2AC8 | -1573.0 |
| POLR2H | -1463.0 |
| MAFB | -1435.0 |
| NCOR1 | -1234.0 |
| EZH2 | -1086.0 |
| H2BC8 | -1029.0 |
| HOXB2 | -727.0 |
| POLR2C | -541.0 |
| H2AZ2 | -340.0 |
| HOXA3 | -136.0 |
| H3-3B | -135.0 |
| POLR2L | -110.0 |
| H4C5 | 878.0 |
| PKNOX1 | 1066.0 |
| RARA | 1135.0 |
| RARG | 1513.0 |
| POLR2E | 1649.0 |
| PIAS2 | 1863.0 |
| H2BC3 | 1920.0 |
| PBX1 | 2227.0 |
| JUN | 2245.0 |
| H2BC1 | 2755.0 |
| NCOA3 | 3306.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| RXRA | 3719.0 |
| EGR2 | 3803.0 |
| H3C2 | 3915.0 |
| H3-3A | 4335.0 |
| RBBP4 | 4375.0 |
| CTCF | 4547.0 |
| POLR2I | 4862.0 |
| ZNF335 | 4989.0 |
| H4C3 | 5053.0 |
| RARB | 5105.0 |
| H3C3 | 5902.0 |
| H3C1 | 6001.0 |
| H2BC11 | 6454.0 |
| H2AC4 | 6905.0 |
| H2BC21 | 7408.0 |
| H2BC12 | 7676.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| POLR2D | 8323.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| POLR2F | 8864.0 |
| H2AZ1 | 8917.0 |
| POLR2G | 9208.0 |
| H2AC14 | 9376.0 |
| H4C9 | 9492.0 |
| PAGR1 | 9803.0 |
| H4C12 | 10027.0 |
| H2BC14 | 10168.0 |
REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS
| 1253 | |
|---|---|
| set | REACTOME_TFAP2_AP_2_FAMILY_REGULATES_TRANSCRIPTION_OF_GROWTH_FACTORS_AND_THEIR_RECEPTORS |
| setSize | 14 |
| pANOVA | 0.00162 |
| s.dist | -0.487 |
| p.adjustANOVA | 0.057 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CGB5 | -10398 |
| YY1 | -9556 |
| TFAP2C | -9348 |
| TFAP2A | -9292 |
| CGB8 | -9069 |
| ERBB2 | -8501 |
| ATAD2 | -7541 |
| CGA | -5492 |
| TFAP2B | -2839 |
| VEGFA | -2830 |
| KIT | 98 |
| TGFA | 1186 |
| ESR1 | 1789 |
| EGFR | 4497 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CGB5 | -10398 |
| YY1 | -9556 |
| TFAP2C | -9348 |
| TFAP2A | -9292 |
| CGB8 | -9069 |
| ERBB2 | -8501 |
| ATAD2 | -7541 |
| CGA | -5492 |
| TFAP2B | -2839 |
| VEGFA | -2830 |
| KIT | 98 |
| TGFA | 1186 |
| ESR1 | 1789 |
| EGFR | 4497 |
REACTOME_CILIUM_ASSEMBLY
| 902 | |
|---|---|
| set | REACTOME_CILIUM_ASSEMBLY |
| setSize | 190 |
| pANOVA | 0.00163 |
| s.dist | -0.133 |
| p.adjustANOVA | 0.057 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| TUBB4B | -9023 |
| DYNLT5 | -8928 |
| DYNC2I1 | -8711 |
| TUBA1C | -8675 |
| WDR19 | -8590 |
| PKD2 | -8449 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| GBF1 | -8249 |
| IFT22 | -7821 |
| CEP164 | -7722 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| TTC21B | -7178 |
| BBS2 | -7084 |
| ODF2 | -7061 |
| NPHP4 | -6826 |
| RAB11A | -6808 |
| PLK1 | -6633 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| TUBA3D | -10323 |
| TUBB4B | -9023 |
| DYNLT5 | -8928 |
| DYNC2I1 | -8711 |
| TUBA1C | -8675 |
| WDR19 | -8590 |
| PKD2 | -8449 |
| TUBA3E | -8293 |
| CEP192 | -8256 |
| GBF1 | -8249 |
| IFT22 | -7821 |
| CEP164 | -7722 |
| CKAP5 | -7526 |
| DYNLL2 | -7477 |
| TTC21B | -7178 |
| BBS2 | -7084 |
| ODF2 | -7061 |
| NPHP4 | -6826 |
| RAB11A | -6808 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| BBIP1 | -6542 |
| BBS10 | -6497 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| EXOC3 | -6324 |
| TUBB2B | -6314 |
| CEP72 | -6174 |
| HAUS5 | -6025 |
| TUBB2A | -5979 |
| DYNLRB1 | -5780 |
| PDE6D | -5747 |
| TRAF3IP1 | -5636 |
| PKD1 | -5568 |
| MARK4 | -5432 |
| CLASP1 | -5346 |
| MKKS | -5255 |
| TTC8 | -5253 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| TUBAL3 | -5043 |
| TUBA4B | -5020 |
| CEP43 | -4973 |
| DYNLRB2 | -4945 |
| CCT2 | -4861 |
| EXOC4 | -4853 |
| SDCCAG8 | -4735 |
| BBS12 | -4710 |
| TUBA1B | -4624 |
| SCLT1 | -4621 |
| PCNT | -4617 |
| WDR35 | -4591 |
| DYNC2LI1 | -4578 |
| CEP250 | -4503 |
| KIF24 | -4463 |
| INPP5E | -4454 |
| TCP1 | -4377 |
| CEP41 | -4178 |
| CEP162 | -4131 |
| TRIP11 | -4089 |
| TUBA8 | -4032 |
| C2CD3 | -4007 |
| TTBK2 | -3924 |
| RAB11FIP3 | -3798 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| ARL6 | -3709 |
| CLUAP1 | -3678 |
| CEP89 | -3583 |
| EXOC7 | -3567 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| EXOC2 | -3292 |
| AKAP9 | -3238 |
| AHI1 | -2990 |
| CEP70 | -2717 |
| B9D2 | -2628 |
| PAFAH1B1 | -2571 |
| RPGRIP1L | -2559 |
| CDK1 | -2219 |
| HAUS6 | -2029 |
| CEP290 | -2002 |
| IFT46 | -1978 |
| ARF4 | -1971 |
| TUBA1A | -1819 |
| CDK5RAP2 | -1570 |
| CCP110 | -1489 |
| ATAT1 | -1243 |
| IFT57 | -1200 |
| NPHP3 | -1171 |
| CEP83 | -1166 |
| IQCB1 | -1155 |
| KIFAP3 | -1087 |
| ASAP1 | -1056 |
| TNPO1 | -607 |
| BBS4 | -564 |
| YWHAE | -521 |
| DCTN1 | -338 |
| NEK2 | -182 |
| CC2D2A | -72 |
| CEP78 | 13 |
| YWHAG | 115 |
| TUBB | 261 |
| IFT140 | 326 |
| TCTN1 | 382 |
| KIF3C | 440 |
| TCTN2 | 482 |
| KIF3B | 591 |
| DYNC2H1 | 665 |
| NEDD1 | 779 |
| FBF1 | 808 |
| RAB3IP | 819 |
| IFT80 | 859 |
| CCT4 | 935 |
| HAUS3 | 961 |
| CENPJ | 1016 |
| TMEM67 | 1049 |
| EXOC8 | 1059 |
| TUBB1 | 1069 |
| BBS5 | 1110 |
| CSNK1E | 1281 |
| CSNK1D | 1496 |
| NPHP1 | 1576 |
| DYNLT2 | 1652 |
| DYNC2I2 | 1671 |
| CYS1 | 1827 |
| RHO | 1851 |
| IFT20 | 1957 |
| CCT8 | 2014 |
| SSNA1 | 2103 |
| IFT27 | 2141 |
| ACTR1A | 2220 |
| SFI1 | 2352 |
| EXOC6 | 2353 |
| SSTR3 | 2424 |
| KIF3A | 2489 |
| MAPRE1 | 2575 |
| CCT5 | 2602 |
| IFT74 | 2677 |
| ARL3 | 2700 |
| ALMS1 | 2804 |
| SMO | 2979 |
| EXOC5 | 3012 |
| RAB8A | 3057 |
| IFT122 | 3162 |
| BBS7 | 3198 |
| TUBA3C | 3214 |
| LZTFL1 | 3370 |
| TUBB6 | 3539 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| TUBB4A | 3612 |
| CCT3 | 3701 |
| B9D1 | 3770 |
| KIF17 | 3923 |
| EXOC1 | 4023 |
| PRKAR2B | 4071 |
| IFT88 | 4264 |
| HSP90AA1 | 4414 |
| BBS9 | 4424 |
| PPP2R1A | 4431 |
| IFT52 | 4480 |
| HAUS2 | 4581 |
| BBS1 | 4767 |
| ARL13B | 4789 |
| HAUS4 | 4825 |
| CEP97 | 4897 |
| DYNLT2B | 5242 |
| HAUS1 | 5311 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| IFT43 | 5933 |
| PRKACA | 6168 |
| TUBB3 | 6221 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| IFT81 | 6460 |
| CNGB1 | 6587 |
| MKS1 | 7244 |
| IFT172 | 7527 |
| TMEM216 | 7587 |
| UNC119B | 8490 |
| MCHR1 | 9187 |
| NINL | 9656 |
| TCTN3 | 9802 |
| CNGA4 | 10986 |
| TUBB8 | 11325 |
REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP
| 486 | |
|---|---|
| set | REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP |
| setSize | 41 |
| pANOVA | 0.00164 |
| s.dist | -0.284 |
| p.adjustANOVA | 0.057 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| ACACB | -9045 |
| FASN | -8998 |
| FDPS | -8743 |
| GPAM | -8535 |
| HMGCR | -8075 |
| PPARA | -8024 |
| NCOA6 | -7292 |
| NCOA1 | -6850 |
| MED1 | -6514 |
| NFYA | -6252 |
| IDI1 | -5711 |
| PMVK | -5688 |
| TM7SF2 | -5204 |
| HELZ2 | -5011 |
| HMGCS1 | -4852 |
| SP1 | -4623 |
| NCOA2 | -4049 |
| SREBF1 | -3956 |
| CREBBP | -3271 |
| ELOVL6 | -3056 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| ACACB | -9045 |
| FASN | -8998 |
| FDPS | -8743 |
| GPAM | -8535 |
| HMGCR | -8075 |
| PPARA | -8024 |
| NCOA6 | -7292 |
| NCOA1 | -6850 |
| MED1 | -6514 |
| NFYA | -6252 |
| IDI1 | -5711 |
| PMVK | -5688 |
| TM7SF2 | -5204 |
| HELZ2 | -5011 |
| HMGCS1 | -4852 |
| SP1 | -4623 |
| NCOA2 | -4049 |
| SREBF1 | -3956 |
| CREBBP | -3271 |
| ELOVL6 | -3056 |
| NFYC | -2954 |
| FDFT1 | -2675 |
| TGS1 | -2634 |
| SQLE | -2104 |
| SC5D | -1600 |
| SREBF2 | -1040 |
| CARM1 | -800 |
| SCD | -297 |
| MVK | -131 |
| ACACA | 3 |
| NFYB | 8 |
| SMARCD3 | 1464 |
| LSS | 1664 |
| GGPS1 | 1875 |
| TBL1XR1 | 2184 |
| CHD9 | 2242 |
| RXRA | 3719 |
| DHCR7 | 3872 |
| MVD | 4411 |
| MTF1 | 5123 |
| CYP51A1 | 5789 |
REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS
| 431 | |
|---|---|
| set | REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS |
| setSize | 101 |
| pANOVA | 0.00166 |
| s.dist | 0.181 |
| p.adjustANOVA | 0.057 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11544 |
| ADH7 | 11354 |
| AOC1 | 11215 |
| CYP4B1 | 11208 |
| CYP2B6 | 11159 |
| ADH1B | 11119 |
| ADH1A | 11059 |
| CES3 | 10801 |
| AOC3 | 10673 |
| CYP8B1 | 10636 |
| FDX2 | 10627 |
| CYP1A2 | 10609 |
| ALDH2 | 10448 |
| CYP2C9 | 10234 |
| CYP3A43 | 10049 |
| CYP2W1 | 9952 |
| CYP11A1 | 9921 |
| CYP4F12 | 9919 |
| CYP4A22 | 9874 |
| ARNT2 | 9786 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CYP21A2 | 11544 |
| ADH7 | 11354 |
| AOC1 | 11215 |
| CYP4B1 | 11208 |
| CYP2B6 | 11159 |
| ADH1B | 11119 |
| ADH1A | 11059 |
| CES3 | 10801 |
| AOC3 | 10673 |
| CYP8B1 | 10636 |
| FDX2 | 10627 |
| CYP1A2 | 10609 |
| ALDH2 | 10448 |
| CYP2C9 | 10234 |
| CYP3A43 | 10049 |
| CYP2W1 | 9952 |
| CYP11A1 | 9921 |
| CYP4F12 | 9919 |
| CYP4A22 | 9874 |
| ARNT2 | 9786 |
| CYP2A13 | 9483 |
| AADAC | 9207 |
| FMO3 | 8931 |
| ALDH3A1 | 8775 |
| AIP | 8261 |
| CYP2R1 | 7985 |
| ALDH1B1 | 7852 |
| CYP2C19 | 7814 |
| NR1H4 | 7526 |
| CYP3A4 | 7504 |
| SMOX | 7477 |
| FDX1 | 7183 |
| CYP4F8 | 6817 |
| FMO1 | 6664 |
| CES1 | 6457 |
| AHR | 6179 |
| CYP51A1 | 5789 |
| EPHX1 | 5504 |
| CYP19A1 | 5423 |
| FMO2 | 5269 |
| CYP1A1 | 5175 |
| CYP1B1 | 4443 |
| ACSS2 | 4137 |
| CYP4F22 | 4047 |
| PAOX | 4022 |
| RXRA | 3719 |
| CYP11B2 | 3493 |
| ADH4 | 3292 |
| MTARC2 | 3227 |
| CYP26A1 | 2987 |
| ARNT | 2360 |
| CYP2D6 | 2094 |
| PTGIS | 1745 |
| CYP2J2 | 1596 |
| CYP3A7 | 1562 |
| CYP2A7 | 1552 |
| CYP7A1 | 1536 |
| CYP2F1 | 1107 |
| CYP2C18 | 1021 |
| CYP27B1 | 369 |
| ALDH1A1 | 176 |
| CYB5R3 | 1 |
| BPHL | -283 |
| CMBL | -330 |
| POR | -491 |
| NQO2 | -507 |
| ADH1C | -603 |
| TBXAS1 | -752 |
| CBR3 | -790 |
| POMC | -950 |
| CYP7B1 | -958 |
| CYP2E1 | -1388 |
| PTGES3 | -1520 |
| CYP46A1 | -1744 |
| CYP11B1 | -1803 |
| CYP26C1 | -2144 |
| FDXR | -2175 |
| CYP2S1 | -2207 |
| CES2 | -2290 |
| CYP4A11 | -2572 |
| PTGS1 | -3067 |
| AOC2 | -3110 |
| NCOA2 | -4049 |
| MTARC1 | -4115 |
| HSP90AB1 | -4117 |
| ADH5 | -4893 |
| CYP4V2 | -5039 |
| CYP4F11 | -5304 |
| CYP2U1 | -5360 |
| CYP4F3 | -5672 |
| CYP26B1 | -6362 |
| CYB5B | -6437 |
| NCOA1 | -6850 |
| CYP24A1 | -7506 |
| CYP39A1 | -7639 |
| CYP2C8 | -7814 |
| CYP27A1 | -7971 |
| ACSS1 | -8369 |
| ADH6 | -9609 |
| CYP3A5 | -9931 |
| CYP4F2 | -10007 |
REACTOME_CHROMATIN_MODIFYING_ENZYMES
| 558 | |
|---|---|
| set | REACTOME_CHROMATIN_MODIFYING_ENZYMES |
| setSize | 252 |
| pANOVA | 0.00182 |
| s.dist | -0.114 |
| p.adjustANOVA | 0.0604 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| HDAC1 | -9320.0 |
| H3C4 | -9267.0 |
| H2AC13 | -9229.0 |
| PAX3 | -9166.0 |
| TAF5L | -9105.0 |
| PHF20 | -8977.0 |
| KDM3B | -8969.0 |
| ATXN7L3 | -8835.0 |
| TRRAP | -8829.0 |
| SETD3 | -8821.0 |
| KMT2A | -8808.0 |
| ELP2 | -8748.0 |
| SUZ12 | -8683.0 |
| KDM1A | -8636.0 |
| H4C13 | -8603.0 |
| KAT8 | -8584.0 |
| KAT7 | -8562.0 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| H3C12 | -9458.0 |
| H2AC7 | -9424.5 |
| H2BC7 | -9424.5 |
| HDAC1 | -9320.0 |
| H3C4 | -9267.0 |
| H2AC13 | -9229.0 |
| PAX3 | -9166.0 |
| TAF5L | -9105.0 |
| PHF20 | -8977.0 |
| KDM3B | -8969.0 |
| ATXN7L3 | -8835.0 |
| TRRAP | -8829.0 |
| SETD3 | -8821.0 |
| KMT2A | -8808.0 |
| ELP2 | -8748.0 |
| SUZ12 | -8683.0 |
| KDM1A | -8636.0 |
| H4C13 | -8603.0 |
| KAT8 | -8584.0 |
| KAT7 | -8562.0 |
| KAT6A | -8514.0 |
| BRPF3 | -8405.0 |
| NSD2 | -8330.0 |
| H2BC13 | -8199.0 |
| H4C16 | -8109.0 |
| ASH2L | -8064.0 |
| KMT2C | -7976.0 |
| H2BC5 | -7799.0 |
| HDAC2 | -7742.0 |
| SETD2 | -7656.0 |
| H2AX | -7648.0 |
| BRPF1 | -7613.0 |
| ARID1B | -7557.0 |
| ATXN7 | -7462.0 |
| ACTL6A | -7457.0 |
| H3C6 | -7372.0 |
| KDM5B | -7300.0 |
| EP400 | -7235.0 |
| EP300 | -7126.0 |
| PHF2 | -7125.0 |
| RUVBL1 | -7114.0 |
| DNMT3A | -7110.0 |
| MCRS1 | -7069.0 |
| NCOR2 | -7068.0 |
| KDM3A | -7021.0 |
| NSD3 | -7002.0 |
| NCOA1 | -6850.0 |
| SMARCB1 | -6836.0 |
| H2BC10 | -6510.0 |
| RIOX2 | -6259.0 |
| SAP130 | -6258.0 |
| EHMT2 | -6169.0 |
| ING5 | -6092.0 |
| VPS72 | -5980.0 |
| ATF7IP | -5790.0 |
| H2AC6 | -5775.0 |
| RBBP5 | -5722.0 |
| SETD1A | -5707.0 |
| WDR5 | -5702.0 |
| H2BC15 | -5694.0 |
| EHMT1 | -5643.0 |
| H3C11 | -5538.0 |
| ARID1A | -5503.0 |
| JAK2 | -5312.0 |
| H2BC6 | -5295.0 |
| KDM4A | -5242.0 |
| YEATS2 | -5129.0 |
| PRMT7 | -5104.0 |
| H2BC4 | -5066.0 |
| H3C8 | -5060.0 |
| SETDB1 | -5045.0 |
| PRMT6 | -4927.0 |
| KANSL2 | -4903.0 |
| KDM5A | -4857.0 |
| CLOCK | -4846.0 |
| TADA3 | -4791.0 |
| PRMT5 | -4702.0 |
| KMT2B | -4692.0 |
| EED | -4626.0 |
| CHD3 | -4537.0 |
| H4C6 | -4534.0 |
| SETD6 | -4435.0 |
| KMT2E | -4425.0 |
| H2AC15 | -4421.0 |
| ZZZ3 | -4320.0 |
| H2BC9 | -4255.5 |
| H3C7 | -4255.5 |
| H2AC25 | -4201.0 |
| H2BC17 | -4192.0 |
| MTA3 | -4106.0 |
| NCOA2 | -4049.0 |
| RCOR1 | -3910.0 |
| H4C4 | -3867.0 |
| KDM7A | -3825.0 |
| H2AJ | -3814.0 |
| SMYD3 | -3808.0 |
| KANSL1 | -3751.0 |
| TADA1 | -3600.0 |
| H2BC26 | -3582.0 |
| KDM2A | -3464.0 |
| KMT2D | -3430.0 |
| CREBBP | -3271.0 |
| ATF2 | -3228.0 |
| ARID2 | -2910.0 |
| USP22 | -2756.0 |
| NFKB1 | -2707.0 |
| KAT2A | -2607.0 |
| DMAP1 | -2584.0 |
| H4C11 | -2488.0 |
| TAF10 | -2411.0 |
| TAF9 | -2337.0 |
| BRWD1 | -2152.0 |
| KDM6B | -2147.0 |
| TADA2B | -2103.0 |
| KAT5 | -1955.0 |
| ARID4B | -1954.0 |
| HDAC3 | -1872.0 |
| H3C10 | -1789.0 |
| KDM4B | -1738.0 |
| RUVBL2 | -1602.0 |
| SMARCA2 | -1590.0 |
| H2AC8 | -1573.0 |
| BRD1 | -1254.0 |
| NCOR1 | -1234.0 |
| KDM4C | -1146.0 |
| EZH2 | -1086.0 |
| NSD1 | -1037.0 |
| KAT2B | -1030.0 |
| H2BC8 | -1029.0 |
| BRD8 | -845.0 |
| COPRS | -817.0 |
| CARM1 | -800.0 |
| SUV39H2 | -776.0 |
| AEBP2 | -722.0 |
| ELP6 | -693.0 |
| HMG20B | -550.0 |
| MEAF6 | -451.0 |
| MECOM | -428.0 |
| SUPT7L | -375.0 |
| H2AZ2 | -340.0 |
| HAT1 | -112.0 |
| MSL1 | -10.0 |
| SMARCA4 | 54.0 |
| TADA2A | 55.0 |
| H2AC17 | 251.0 |
| KDM1B | 262.0 |
| ELP4 | 304.0 |
| SETD7 | 320.0 |
| SMARCE1 | 449.0 |
| MBD3 | 653.0 |
| ARID4A | 820.0 |
| GATAD2A | 857.0 |
| SETD1B | 870.0 |
| H4C5 | 878.0 |
| JADE1 | 956.0 |
| H2AC21 | 971.0 |
| PHF21A | 1221.0 |
| DOT1L | 1252.0 |
| SMYD2 | 1350.0 |
| SAP18 | 1462.0 |
| SMARCD3 | 1464.0 |
| SGF29 | 1503.0 |
| SMARCD1 | 1681.0 |
| H2AC16 | 1717.0 |
| H2BC3 | 1920.0 |
| ASH1L | 1931.0 |
| HDAC10 | 2020.0 |
| GATAD2B | 2023.0 |
| TBL1XR1 | 2184.0 |
| KDM2B | 2417.0 |
| MSL2 | 2618.0 |
| SUPT20H | 2660.0 |
| MTA1 | 2697.0 |
| ENY2 | 2722.0 |
| H2BC1 | 2755.0 |
| TAF6L | 2817.0 |
| ING3 | 2835.0 |
| MBIP | 3035.0 |
| KAT6B | 3232.0 |
| RELA | 3308.0 |
| H4C8 | 3367.0 |
| H4C2 | 3408.0 |
| SMARCC2 | 3457.0 |
| WDR77 | 3502.0 |
| KMT5C | 3578.0 |
| SUPT3H | 3668.0 |
| H2AC11 | 3693.0 |
| H3C2 | 3915.0 |
| ARID5B | 4111.0 |
| ELP3 | 4171.0 |
| CHD4 | 4230.0 |
| CCND1 | 4294.0 |
| RBBP4 | 4375.0 |
| SUDS3 | 4380.0 |
| CDK4 | 4604.0 |
| KMT5B | 4614.0 |
| MRGBP | 4695.0 |
| PADI1 | 4742.0 |
| RPS2 | 4762.0 |
| EPC1 | 4763.0 |
| SETDB2 | 4817.0 |
| H4C3 | 5053.0 |
| ACTB | 5155.0 |
| NFKB2 | 5274.0 |
| TAF12 | 5290.0 |
| KMT5A | 5304.0 |
| KANSL3 | 5754.0 |
| H2AC1 | 5861.0 |
| JMJD6 | 5878.0 |
| H3C3 | 5902.0 |
| PRMT3 | 5952.0 |
| BRMS1 | 5975.0 |
| H3C1 | 6001.0 |
| ING4 | 6201.0 |
| SMARCC1 | 6298.0 |
| REST | 6437.0 |
| H2BC11 | 6454.0 |
| PRDM9 | 6466.0 |
| ELP1 | 6531.0 |
| PBRM1 | 6627.0 |
| H2AC12 | 6666.0 |
| H2AC4 | 6905.0 |
| SAP30 | 6962.0 |
| DPY30 | 7120.0 |
| PRMT1 | 7139.0 |
| H2BC21 | 7408.0 |
| DR1 | 7448.0 |
| H2BC12 | 7676.0 |
| ACTL6B | 7777.0 |
| ELP5 | 7971.0 |
| PRDM16 | 8174.0 |
| H2AC18 | 8201.5 |
| H2AC19 | 8201.5 |
| GPS2 | 8219.0 |
| YEATS4 | 8293.0 |
| KDM4D | 8297.0 |
| MTA2 | 8451.0 |
| JADE2 | 8545.0 |
| SMARCD2 | 8676.0 |
| H2AC20 | 8750.0 |
| H4C1 | 8782.0 |
| H2AZ1 | 8917.0 |
| MORF4L1 | 9278.0 |
| H2AC14 | 9376.0 |
| PADI4 | 9453.0 |
| H4C9 | 9492.0 |
| SAP30L | 9539.0 |
| PADI3 | 9923.0 |
| H4C12 | 10027.0 |
| H2BC14 | 10168.0 |
| PADI6 | 10906.0 |
| PADI2 | 11065.0 |
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES
| 616 | |
|---|---|
| set | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES |
| setSize | 78 |
| pANOVA | 0.00184 |
| s.dist | -0.204 |
| p.adjustANOVA | 0.0604 |
Top
enriched genes
| GeneID | Gene Rank |
|---|---|
| CDK11A | -9721 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| TUBG2 | -8420 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CDK11B | -7666 |
| CKAP5 | -7526 |
| ODF2 | -7061 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| CEP72 | -6174 |
| HAUS5 | -6025 |
Click HERE to show all gene set members
| GeneID | Gene Rank |
|---|---|
| CDK11A | -9721 |
| TUBGCP4 | -9141 |
| TUBB4B | -9023 |
| TUBG2 | -8420 |
| CEP192 | -8256 |
| MZT2A | -8243 |
| MZT1 | -8047 |
| CEP164 | -7722 |
| CDK11B | -7666 |
| CKAP5 | -7526 |
| ODF2 | -7061 |
| PLK1 | -6633 |
| TUBA4A | -6626 |
| DCTN3 | -6556 |
| PCM1 | -6483 |
| DYNC1H1 | -6464 |
| CEP152 | -6444 |
| CEP131 | -6383 |
| CEP72 | -6174 |
| HAUS5 | -6025 |
| TUBGCP5 | -5800 |
| TUBGCP6 | -5669 |
| CLASP1 | -5346 |
| DYNC1I2 | -5131 |
| CEP63 | -5092 |
| CEP43 | -4973 |
| SDCCAG8 | -4735 |
| PCNT | -4617 |
| CEP250 | -4503 |
| CEP41 | -4178 |
| CNTRL | -3781 |
| CEP76 | -3720 |
| NDE1 | -3562 |
| DYNLL1 | -3550 |
| AKAP9 | -3238 |
| CEP70 | -2717 |
| PAFAH1B1 | -2571 |
| CDK1 | -2219 |
| HAUS6 | -2029 |
| CEP290 | -2002 |
| TUBGCP3 | -1900 |
| TUBA1A | -1819 |
| CDK5RAP2 | -1570 |
| CCP110 | -1489 |
| YWHAE | -521 |
| DCTN1 | -338 |
| TUBGCP2 | -268 |
| NEK2 | -182 |
| CEP78 | 13 |
| YWHAG | 115 |
| TUBB | 261 |
| NEDD1 | 779 |
| HAUS3 | 961 |
| NME7 | 1011 |
| CENPJ | 1016 |
| CSNK1E | 1281 |
| CSNK1D | 1496 |
| SSNA1 | 2103 |
| ACTR1A | 2220 |
| SFI1 | 2352 |
| MAPRE1 | 2575 |
| ALMS1 | 2804 |
| CEP57 | 3574 |
| PLK4 | 3579 |
| TUBB4A | 3612 |
| PRKAR2B | 4071 |
| HSP90AA1 | 4414 |
| PPP2R1A | 4431 |
| HAUS2 | 4581 |
| HAUS4 | 4825 |
| HAUS1 | 5311 |
| TUBG1 | 5806 |
| CEP135 | 5819 |
| PRKACA | 6168 |
| DCTN2 | 6256 |
| HAUS8 | 6365 |
| MZT2B | 6651 |
| NINL | 9656 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so; LAPACK version 3.10.0
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## time zone: Etc/UTC
## tzcode source: system (glibc)
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.3.3
## [2] GGally_2.2.0
## [3] ggplot2_3.4.4
## [4] reshape2_1.4.4
## [5] gtools_3.9.5
## [6] tibble_3.2.1
## [7] dplyr_1.1.4
## [8] echarts4r_0.4.5
## [9] png_0.1-8
## [10] gridExtra_2.3
## [11] missMethyl_1.36.0
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1
## [13] beeswarm_0.4.0
## [14] kableExtra_1.3.4
## [15] gplots_3.1.3
## [16] mitch_1.15.0
## [17] tictoc_1.2
## [18] HGNChelper_0.8.1
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0
## [21] minfi_1.48.0
## [22] bumphunter_1.44.0
## [23] locfit_1.5-9.8
## [24] iterators_1.0.14
## [25] foreach_1.5.2
## [26] Biostrings_2.70.1
## [27] XVector_0.42.0
## [28] SummarizedExperiment_1.32.0
## [29] Biobase_2.62.0
## [30] MatrixGenerics_1.14.0
## [31] matrixStats_1.2.0
## [32] GenomicRanges_1.54.1
## [33] GenomeInfoDb_1.38.2
## [34] IRanges_2.36.0
## [35] S4Vectors_0.40.2
## [36] BiocGenerics_0.48.1
## [37] eulerr_7.0.0
## [38] limma_3.58.1
##
## loaded via a namespace (and not attached):
## [1] splines_4.3.2 later_1.3.2
## [3] BiocIO_1.12.0 bitops_1.0-7
## [5] filelock_1.0.3 preprocessCore_1.64.0
## [7] XML_3.99-0.16 lifecycle_1.0.4
## [9] lattice_0.22-5 MASS_7.3-60
## [11] base64_2.0.1 scrime_1.3.5
## [13] magrittr_2.0.3 sass_0.4.8
## [15] rmarkdown_2.25 jquerylib_0.1.4
## [17] yaml_2.3.8 httpuv_1.6.13
## [19] doRNG_1.8.6 askpass_1.2.0
## [21] DBI_1.1.3 RColorBrewer_1.1-3
## [23] abind_1.4-5 zlibbioc_1.48.0
## [25] rvest_1.0.3 quadprog_1.5-8
## [27] purrr_1.0.2 RCurl_1.98-1.13
## [29] rappdirs_0.3.3 GenomeInfoDbData_1.2.11
## [31] genefilter_1.84.0 annotate_1.80.0
## [33] svglite_2.1.3 DelayedMatrixStats_1.24.0
## [35] codetools_0.2-19 DelayedArray_0.28.0
## [37] xml2_1.3.6 tidyselect_1.2.0
## [39] beanplot_1.3.1 BiocFileCache_2.10.1
## [41] webshot_0.5.5 illuminaio_0.44.0
## [43] GenomicAlignments_1.38.0 jsonlite_1.8.8
## [45] multtest_2.58.0 ellipsis_0.3.2
## [47] survival_3.5-7 systemfonts_1.0.5
## [49] tools_4.3.2 progress_1.2.3
## [51] Rcpp_1.0.11 glue_1.6.2
## [53] SparseArray_1.2.2 xfun_0.41
## [55] HDF5Array_1.30.0 withr_2.5.2
## [57] fastmap_1.1.1 rhdf5filters_1.14.1
## [59] fansi_1.0.6 openssl_2.1.1
## [61] caTools_1.18.2 digest_0.6.33
## [63] R6_2.5.1 mime_0.12
## [65] colorspace_2.1-0 biomaRt_2.58.0
## [67] RSQLite_2.3.4 utf8_1.2.4
## [69] tidyr_1.3.0 generics_0.1.3
## [71] data.table_1.14.10 rtracklayer_1.62.0
## [73] prettyunits_1.2.0 httr_1.4.7
## [75] htmlwidgets_1.6.4 S4Arrays_1.2.0
## [77] ggstats_0.5.1 pkgconfig_2.0.3
## [79] gtable_0.3.4 blob_1.2.4
## [81] siggenes_1.76.0 htmltools_0.5.7
## [83] scales_1.3.0 rstudioapi_0.15.0
## [85] knitr_1.45 tzdb_0.4.0
## [87] rjson_0.2.21 nlme_3.1-163
## [89] curl_5.2.0 org.Hs.eg.db_3.18.0
## [91] cachem_1.0.8 rhdf5_2.46.1
## [93] stringr_1.5.1 KernSmooth_2.23-22
## [95] AnnotationDbi_1.64.1 restfulr_0.0.15
## [97] GEOquery_2.70.0 pillar_1.9.0
## [99] grid_4.3.2 reshape_0.8.9
## [101] vctrs_0.6.5 promises_1.2.1
## [103] dbplyr_2.4.0 xtable_1.8-4
## [105] evaluate_0.23 readr_2.1.4
## [107] GenomicFeatures_1.54.1 cli_3.6.2
## [109] compiler_4.3.2 Rsamtools_2.18.0
## [111] rlang_1.1.2 crayon_1.5.2
## [113] rngtools_1.5.2 nor1mix_1.3-2
## [115] mclust_6.0.1 plyr_1.8.9
## [117] stringi_1.8.3 viridisLite_0.4.2
## [119] BiocParallel_1.36.0 munsell_0.5.0
## [121] Matrix_1.6-1.1 hms_1.1.3
## [123] sparseMatrixStats_1.14.0 bit64_4.0.5
## [125] Rhdf5lib_1.24.1 KEGGREST_1.42.0
## [127] statmod_1.5.0 shiny_1.8.0
## [129] highr_0.10 memoise_2.0.1
## [131] bslib_0.6.1 bit_4.0.5END of report