date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG 0.0022200
A1BG-AS1 0.0031032
A1CF 0.0029513
A2M 0.0011884
A2M-AS1 0.0002487
A2ML1 0.0002089

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 3.01e-21 0.2950 4.94e-18
REACTOME SENSORY PERCEPTION 555 5.33e-15 0.1940 4.38e-12
REACTOME DRUG ADME 103 5.50e-05 0.2300 2.75e-02
REACTOME ASPIRIN ADME 42 6.70e-05 0.3550 2.75e-02
REACTOME KERATINIZATION 210 1.02e-04 0.1560 3.34e-02
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.78e-04 -0.1590 4.35e-02
REACTOME NEUTROPHIL DEGRANULATION 460 1.86e-04 -0.1020 4.35e-02
REACTOME INNATE IMMUNE SYSTEM 1002 7.22e-04 -0.0631 1.48e-01
REACTOME ELASTIC FIBRE FORMATION 44 1.37e-03 -0.2790 2.49e-01
REACTOME BETA DEFENSINS 27 2.15e-03 0.3410 3.32e-01
REACTOME SIGNALING BY NTRKS 132 2.49e-03 -0.1520 3.32e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 2.55e-03 -0.3180 3.32e-01
REACTOME GLUCURONIDATION 23 2.83e-03 0.3600 3.32e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.92e-03 -0.2870 3.32e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 3.23e-03 -0.0840 3.32e-01
REACTOME SIGNALING BY GPCR 673 3.24e-03 -0.0666 3.32e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 3.85e-03 -0.2250 3.72e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 4.16e-03 -0.0943 3.79e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 5.27e-03 -0.1880 4.56e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 5.84e-03 -0.2370 4.58e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 5.86e-03 -0.2620 4.58e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 6.37e-03 -0.7040 4.76e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 6.97e-03 0.1920 4.98e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 7.89e-03 -0.0590 5.11e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 8.17e-03 0.4610 5.11e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 9.27e-03 -0.2290 5.11e-01
REACTOME GPCR LIGAND BINDING 444 9.58e-03 -0.0717 5.11e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 9.75e-03 0.6090 5.11e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 9.77e-03 0.1940 5.11e-01
REACTOME DEFENSINS 33 9.80e-03 0.2600 5.11e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 9.89e-03 -0.2090 5.11e-01
REACTOME CIRCADIAN CLOCK 68 9.96e-03 -0.1810 5.11e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 1.08e-02 -0.3680 5.29e-01
REACTOME METABOLISM OF LIPIDS 709 1.10e-02 -0.0561 5.29e-01
REACTOME LEISHMANIA INFECTION 156 1.22e-02 -0.1160 5.46e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 1.26e-02 -0.1300 5.46e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 1.26e-02 -0.3490 5.46e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.28e-02 0.1830 5.46e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 1.30e-02 -0.2460 5.46e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.36e-02 0.1460 5.46e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 1.40e-02 -0.2050 5.46e-01
REACTOME BIOLOGICAL OXIDATIONS 210 1.42e-02 0.0981 5.46e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.48e-02 -0.0545 5.46e-01
REACTOME SIGNALING BY INTERLEUKINS 444 1.48e-02 -0.0674 5.46e-01
REACTOME GPER1 SIGNALING 45 1.50e-02 -0.2100 5.46e-01
REACTOME PHOSPHOLIPID METABOLISM 201 1.62e-02 -0.0984 5.67e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 1.63e-02 -0.2580 5.67e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 1.69e-02 -0.2370 5.67e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 1.73e-02 -0.2750 5.67e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 1.77e-02 0.1770 5.67e-01


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY 348 3.01e-21 2.95e-01 4.94e-18
REACTOME SENSORY PERCEPTION 555 5.33e-15 1.94e-01 4.38e-12
REACTOME DRUG ADME 103 5.50e-05 2.30e-01 2.75e-02
REACTOME ASPIRIN ADME 42 6.70e-05 3.55e-01 2.75e-02
REACTOME KERATINIZATION 210 1.02e-04 1.56e-01 3.34e-02
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 1.78e-04 -1.59e-01 4.35e-02
REACTOME NEUTROPHIL DEGRANULATION 460 1.86e-04 -1.02e-01 4.35e-02
REACTOME INNATE IMMUNE SYSTEM 1002 7.22e-04 -6.31e-02 1.48e-01
REACTOME ELASTIC FIBRE FORMATION 44 1.37e-03 -2.79e-01 2.49e-01
REACTOME BETA DEFENSINS 27 2.15e-03 3.41e-01 3.32e-01
REACTOME SIGNALING BY NTRKS 132 2.49e-03 -1.52e-01 3.32e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 2.55e-03 -3.18e-01 3.32e-01
REACTOME GLUCURONIDATION 23 2.83e-03 3.60e-01 3.32e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 2.92e-03 -2.87e-01 3.32e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 3.23e-03 -8.40e-02 3.32e-01
REACTOME SIGNALING BY GPCR 673 3.24e-03 -6.66e-02 3.32e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 3.85e-03 -2.25e-01 3.72e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 4.16e-03 -9.43e-02 3.79e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 5.27e-03 -1.88e-01 4.56e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 5.84e-03 -2.37e-01 4.58e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 5.86e-03 -2.62e-01 4.58e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 6.37e-03 -7.04e-01 4.76e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 6.97e-03 1.92e-01 4.98e-01
REACTOME TRANSPORT OF SMALL MOLECULES 697 7.89e-03 -5.90e-02 5.11e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 8.17e-03 4.61e-01 5.11e-01
REACTOME INTERLEUKIN 10 SIGNALING 43 9.27e-03 -2.29e-01 5.11e-01
REACTOME GPCR LIGAND BINDING 444 9.58e-03 -7.17e-02 5.11e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 9.75e-03 6.09e-01 5.11e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 9.77e-03 1.94e-01 5.11e-01
REACTOME DEFENSINS 33 9.80e-03 2.60e-01 5.11e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 9.89e-03 -2.09e-01 5.11e-01
REACTOME CIRCADIAN CLOCK 68 9.96e-03 -1.81e-01 5.11e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 1.08e-02 -3.68e-01 5.29e-01
REACTOME METABOLISM OF LIPIDS 709 1.10e-02 -5.61e-02 5.29e-01
REACTOME LEISHMANIA INFECTION 156 1.22e-02 -1.16e-01 5.46e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 1.26e-02 -1.30e-01 5.46e-01
REACTOME RORA ACTIVATES GENE EXPRESSION 17 1.26e-02 -3.49e-01 5.46e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 1.28e-02 1.83e-01 5.46e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 1.30e-02 -2.46e-01 5.46e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 1.36e-02 1.46e-01 5.46e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 1.40e-02 -2.05e-01 5.46e-01
REACTOME BIOLOGICAL OXIDATIONS 210 1.42e-02 9.81e-02 5.46e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 1.48e-02 -5.45e-02 5.46e-01
REACTOME SIGNALING BY INTERLEUKINS 444 1.48e-02 -6.74e-02 5.46e-01
REACTOME GPER1 SIGNALING 45 1.50e-02 -2.10e-01 5.46e-01
REACTOME PHOSPHOLIPID METABOLISM 201 1.62e-02 -9.84e-02 5.67e-01
REACTOME INSULIN RECEPTOR RECYCLING 29 1.63e-02 -2.58e-01 5.67e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 1.69e-02 -2.37e-01 5.67e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 1.73e-02 -2.75e-01 5.67e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 1.77e-02 1.77e-01 5.67e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 1.85e-02 -2.49e-01 5.67e-01
REACTOME GLYCOLYSIS 70 1.86e-02 -1.63e-01 5.67e-01
REACTOME ABACAVIR ADME 9 1.89e-02 4.52e-01 5.67e-01
REACTOME SPRY REGULATION OF FGF SIGNALING 16 1.93e-02 -3.38e-01 5.67e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 1.93e-02 4.77e-01 5.67e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 1.96e-02 -9.74e-02 5.67e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 1.97e-02 -3.09e-01 5.67e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 2.03e-02 1.33e-01 5.72e-01
REACTOME RSK ACTIVATION 5 2.06e-02 -5.98e-01 5.72e-01
REACTOME AMINO ACID CONJUGATION 9 2.10e-02 4.44e-01 5.72e-01
REACTOME VLDL ASSEMBLY 5 2.16e-02 -5.93e-01 5.72e-01
REACTOME SIGNALING BY HEDGEHOG 148 2.17e-02 -1.09e-01 5.72e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 2.25e-02 5.38e-01 5.72e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 2.26e-02 -9.65e-02 5.72e-01
REACTOME ONCOGENE INDUCED SENESCENCE 35 2.26e-02 -2.23e-01 5.72e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 2.31e-02 -2.03e-01 5.75e-01
REACTOME NEURONAL SYSTEM 388 2.59e-02 -6.59e-02 6.23e-01
REACTOME SYNTHESIS OF PG 8 2.61e-02 -4.54e-01 6.23e-01
REACTOME RND1 GTPASE CYCLE 41 2.62e-02 2.01e-01 6.23e-01
REACTOME OTHER INTERLEUKIN SIGNALING 24 2.77e-02 -2.60e-01 6.42e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 2.78e-02 -2.49e-01 6.42e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 2.90e-02 3.64e-01 6.42e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 2.97e-02 -2.07e-01 6.42e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 3.00e-02 -3.35e-01 6.42e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 3.06e-02 -1.17e-01 6.42e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 3.09e-02 -1.61e-01 6.42e-01
REACTOME SIGNALING BY NODAL 20 3.12e-02 -2.78e-01 6.42e-01
REACTOME GAP JUNCTION DEGRADATION 12 3.15e-02 -3.59e-01 6.42e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 3.18e-02 2.04e-01 6.42e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 3.24e-02 -7.29e-02 6.42e-01
REACTOME G ALPHA Q SIGNALLING EVENTS 206 3.30e-02 -8.62e-02 6.42e-01
REACTOME ACTIVATION OF SMO 18 3.31e-02 -2.90e-01 6.42e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 3.33e-02 2.82e-01 6.42e-01
REACTOME SIGNALING BY ACTIVIN 15 3.34e-02 -3.17e-01 6.42e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 3.34e-02 -4.34e-01 6.42e-01
REACTOME DNA METHYLATION 58 3.44e-02 1.61e-01 6.42e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 3.48e-02 -1.05e-01 6.42e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 3.53e-02 -1.88e-01 6.42e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 3.55e-02 -3.51e-01 6.42e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 3.57e-02 2.86e-01 6.42e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 3.59e-02 -4.95e-01 6.42e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 3.60e-02 -1.58e-01 6.42e-01
REACTOME MEIOTIC RECOMBINATION 80 3.71e-02 1.35e-01 6.47e-01
REACTOME VESICLE MEDIATED TRANSPORT 642 3.71e-02 -4.82e-02 6.47e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 3.82e-02 -2.39e-01 6.59e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 3.85e-02 -4.52e-01 6.59e-01
REACTOME FORMATION OF AXIAL MESODERM 14 3.98e-02 -3.17e-01 6.62e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 4.04e-02 3.28e-01 6.62e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 4.06e-02 1.47e-01 6.62e-01
REACTOME G ALPHA I SIGNALLING EVENTS 304 4.09e-02 -6.82e-02 6.62e-01
REACTOME NGF STIMULATED TRANSCRIPTION 38 4.16e-02 -1.91e-01 6.62e-01
REACTOME OPIOID SIGNALLING 89 4.19e-02 -1.25e-01 6.62e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 4.23e-02 -2.39e-01 6.62e-01
REACTOME POTASSIUM CHANNELS 102 4.26e-02 -1.16e-01 6.62e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 4.26e-02 -7.37e-02 6.62e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 4.28e-02 -2.14e-01 6.62e-01
REACTOME CLEC7A DECTIN 1 SIGNALING 97 4.33e-02 -1.19e-01 6.62e-01
REACTOME RHO GTPASES ACTIVATE PKNS 86 4.37e-02 1.26e-01 6.62e-01
REACTOME N GLYCAN ANTENNAE ELONGATION 15 4.40e-02 -3.00e-01 6.62e-01
REACTOME OPSINS 7 4.48e-02 4.38e-01 6.67e-01
REACTOME DEATH RECEPTOR SIGNALING 143 4.51e-02 -9.71e-02 6.67e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 4.66e-02 -2.21e-01 6.68e-01
REACTOME TNF SIGNALING 54 4.71e-02 -1.56e-01 6.68e-01
REACTOME VLDL CLEARANCE 6 4.73e-02 -4.68e-01 6.68e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 4.79e-02 -3.05e-01 6.68e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 4.87e-02 2.76e-01 6.68e-01
REACTOME G PROTEIN MEDIATED EVENTS 53 4.88e-02 -1.56e-01 6.68e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 4.92e-02 -2.01e-01 6.68e-01
REACTOME CIPROFLOXACIN ADME 5 4.93e-02 5.08e-01 6.68e-01
REACTOME HEME DEGRADATION 15 4.95e-02 2.93e-01 6.68e-01
REACTOME NUCLEOTIDE CATABOLISM 35 5.04e-02 -1.91e-01 6.68e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 5.08e-02 -1.31e-01 6.68e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 5.15e-02 -3.75e-01 6.68e-01
REACTOME HEDGEHOG ON STATE 85 5.15e-02 -1.22e-01 6.68e-01
REACTOME MEMBRANE TRAFFICKING 603 5.17e-02 -4.64e-02 6.68e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 5.20e-02 -1.31e-01 6.68e-01
REACTOME INTERLEUKIN 2 SIGNALING 11 5.22e-02 -3.38e-01 6.68e-01
REACTOME RECYCLING PATHWAY OF L1 43 5.27e-02 -1.71e-01 6.68e-01
REACTOME MITOTIC SPINDLE CHECKPOINT 109 5.28e-02 1.07e-01 6.68e-01
REACTOME CELLULAR RESPONSES TO STIMULI 779 5.29e-02 -4.08e-02 6.68e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 5.37e-02 -2.98e-01 6.73e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 5.46e-02 1.35e-01 6.79e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 5.68e-02 1.62e-01 6.89e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 5.70e-02 -1.35e-01 6.89e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 5.70e-02 -1.83e-01 6.89e-01
REACTOME SYNTHESIS OF LIPOXINS LX 6 5.78e-02 -4.47e-01 6.89e-01
REACTOME CA DEPENDENT EVENTS 36 5.80e-02 -1.83e-01 6.89e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 5.82e-02 -3.30e-01 6.89e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 5.83e-02 -2.03e-01 6.89e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 5.91e-02 -1.61e-01 6.93e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 5.95e-02 -2.72e-01 6.93e-01
REACTOME INTERLEUKIN 37 SIGNALING 20 6.07e-02 -2.42e-01 7.01e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 6.10e-02 -2.79e-01 7.01e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 6.26e-02 -1.16e-01 7.10e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 6.27e-02 -4.83e-02 7.10e-01
REACTOME DNA REPLICATION PRE INITIATION 150 6.40e-02 8.76e-02 7.14e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 6.44e-02 -4.04e-01 7.14e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 6.46e-02 -1.98e-01 7.14e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 6.52e-02 -2.32e-01 7.14e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 6.56e-02 1.07e-01 7.14e-01
REACTOME GABA B RECEPTOR ACTIVATION 43 6.59e-02 -1.62e-01 7.14e-01
REACTOME GABA RECEPTOR ACTIVATION 57 6.68e-02 -1.40e-01 7.14e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 6.71e-02 -3.52e-01 7.14e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 6.73e-02 -8.80e-02 7.14e-01
REACTOME IRON UPTAKE AND TRANSPORT 56 6.74e-02 -1.41e-01 7.14e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 6.84e-02 -3.51e-01 7.16e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 6.84e-02 -1.34e-01 7.16e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 6.89e-02 -3.32e-01 7.16e-01
REACTOME MAPK FAMILY SIGNALING CASCADES 314 6.97e-02 -5.95e-02 7.19e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 7.01e-02 -4.27e-01 7.19e-01
REACTOME CHROMATIN MODIFYING ENZYMES 252 7.10e-02 -6.60e-02 7.24e-01
REACTOME CREB3 FACTORS ACTIVATE GENES 8 7.17e-02 -3.68e-01 7.27e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 7.31e-02 -1.83e-01 7.34e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 7.41e-02 -1.31e-01 7.34e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 7.43e-02 -2.86e-01 7.34e-01
REACTOME DAG AND IP3 SIGNALING 40 7.43e-02 -1.63e-01 7.34e-01
REACTOME CYTOPROTECTION BY HMOX1 59 7.47e-02 -1.34e-01 7.34e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 7.57e-02 -4.19e-01 7.38e-01
REACTOME ONCOGENIC MAPK SIGNALING 79 7.61e-02 -1.15e-01 7.38e-01
REACTOME TBC RABGAPS 40 7.71e-02 -1.62e-01 7.38e-01
REACTOME CA2 PATHWAY 62 7.78e-02 -1.29e-01 7.38e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 7.78e-02 3.60e-01 7.38e-01
REACTOME G ALPHA S SIGNALLING EVENTS 155 7.84e-02 -8.19e-02 7.38e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 7.86e-02 -1.28e-01 7.38e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 7.87e-02 -4.54e-01 7.38e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 7.91e-02 2.21e-01 7.38e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 8.00e-02 -2.38e-01 7.40e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 8.03e-02 1.40e-01 7.40e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 8.08e-02 4.51e-01 7.40e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 8.17e-02 -1.06e-01 7.40e-01
REACTOME MITOTIC PROPHASE 134 8.19e-02 8.70e-02 7.40e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 8.21e-02 -1.53e-01 7.40e-01
REACTOME SYNTHESIS OF PE 13 8.25e-02 -2.78e-01 7.40e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 8.38e-02 -3.77e-01 7.44e-01
REACTOME FREE FATTY ACID RECEPTORS 5 8.39e-02 4.46e-01 7.44e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 8.47e-02 -2.08e-01 7.44e-01
REACTOME FATTY ACIDS 15 8.48e-02 2.57e-01 7.44e-01
REACTOME SODIUM PROTON EXCHANGERS 7 8.52e-02 -3.76e-01 7.44e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 8.61e-02 -5.77e-02 7.47e-01
REACTOME CELL CYCLE CHECKPOINTS 284 8.65e-02 5.91e-02 7.47e-01
REACTOME BIOSYNTHESIS OF MARESINS 8 8.80e-02 3.48e-01 7.47e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 8.80e-02 -2.01e-01 7.47e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 8.85e-02 -3.28e-01 7.47e-01
REACTOME APOPTOTIC EXECUTION PHASE 49 8.98e-02 1.40e-01 7.47e-01
REACTOME FRUCTOSE CATABOLISM 5 8.98e-02 -4.38e-01 7.47e-01
REACTOME RHO GTPASE EFFECTORS 305 8.99e-02 5.65e-02 7.47e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 9.08e-02 -3.69e-01 7.47e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 9.13e-02 4.36e-01 7.47e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 9.22e-02 -1.11e-01 7.47e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 9.24e-02 -2.36e-01 7.47e-01
REACTOME PREGNENOLONE BIOSYNTHESIS 12 9.27e-02 -2.80e-01 7.47e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 9.42e-02 -2.16e-01 7.47e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 9.50e-02 -4.16e-02 7.47e-01
REACTOME CHOLINE CATABOLISM 6 9.50e-02 3.94e-01 7.47e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 9.52e-02 -7.67e-02 7.47e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 9.54e-02 -1.31e-01 7.47e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 9.55e-02 -4.31e-01 7.47e-01
REACTOME BILE ACID AND BILE SALT METABOLISM 45 9.56e-02 1.44e-01 7.47e-01
REACTOME HYDROLYSIS OF LPC 9 9.63e-02 -3.20e-01 7.47e-01
REACTOME SODIUM CALCIUM EXCHANGERS 11 9.63e-02 -2.90e-01 7.47e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 9.65e-02 -1.36e-01 7.47e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 9.71e-02 3.39e-01 7.47e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 9.78e-02 -2.19e-01 7.47e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 9.78e-02 -1.51e-01 7.47e-01
REACTOME NTRK2 ACTIVATES RAC1 5 9.78e-02 -4.28e-01 7.47e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 9.90e-02 2.87e-01 7.52e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 9.96e-02 -1.02e-01 7.52e-01
REACTOME PROCESSING OF SMDT1 16 9.98e-02 2.38e-01 7.52e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 1.02e-01 -8.68e-02 7.63e-01
REACTOME DIGESTION OF DIETARY LIPID 7 1.02e-01 3.56e-01 7.65e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 1.04e-01 -2.51e-01 7.72e-01
REACTOME DNA REPLICATION 178 1.05e-01 7.04e-02 7.73e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 1.05e-01 1.03e-01 7.73e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 1.05e-01 -2.20e-01 7.73e-01
REACTOME INTESTINAL ABSORPTION 5 1.06e-01 -4.17e-01 7.73e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 1.07e-01 -1.60e-01 7.73e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 1.08e-01 -2.32e-01 7.73e-01
REACTOME GASTRULATION 49 1.08e-01 -1.33e-01 7.73e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 1.09e-01 -8.82e-02 7.73e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.09e-01 8.40e-02 7.73e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 1.10e-01 -1.28e-01 7.73e-01
REACTOME PHASE 2 PLATEAU PHASE 14 1.10e-01 -2.47e-01 7.73e-01
REACTOME METABOLISM OF CARBOHYDRATES 279 1.10e-01 -5.56e-02 7.73e-01
REACTOME CARGO CONCENTRATION IN THE ER 32 1.12e-01 -1.63e-01 7.73e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 1.12e-01 -2.30e-01 7.73e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 1.12e-01 4.10e-01 7.73e-01
REACTOME HCMV LATE EVENTS 110 1.13e-01 8.75e-02 7.73e-01
REACTOME MEIOSIS 110 1.13e-01 8.75e-02 7.73e-01
REACTOME ERKS ARE INACTIVATED 13 1.13e-01 -2.54e-01 7.73e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 1.14e-01 1.05e-01 7.73e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 1.14e-01 -9.54e-02 7.73e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 1.14e-01 1.79e-01 7.73e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 1.15e-01 -2.63e-01 7.74e-01
REACTOME G ALPHA Z SIGNALLING EVENTS 48 1.16e-01 -1.31e-01 7.76e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 1.16e-01 1.98e-01 7.76e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 1.18e-01 -2.19e-01 7.89e-01
REACTOME GENE SILENCING BY RNA 133 1.19e-01 7.83e-02 7.89e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 1.19e-01 -3.67e-01 7.91e-01
REACTOME STRIATED MUSCLE CONTRACTION 35 1.20e-01 -1.52e-01 7.92e-01
REACTOME INTEGRATION OF ENERGY METABOLISM 105 1.22e-01 -8.73e-02 8.03e-01
REACTOME MELANIN BIOSYNTHESIS 5 1.23e-01 3.98e-01 8.03e-01
REACTOME PROTEIN REPAIR 6 1.25e-01 3.62e-01 8.03e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.25e-01 8.88e-02 8.03e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 1.25e-01 1.93e-01 8.03e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 1.25e-01 -1.57e-01 8.03e-01
REACTOME LIGAND RECEPTOR INTERACTIONS 8 1.26e-01 -3.13e-01 8.03e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 1.26e-01 -2.03e-01 8.03e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 1.28e-01 -1.37e-01 8.03e-01
REACTOME DISSOLUTION OF FIBRIN CLOT 13 1.29e-01 2.43e-01 8.03e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 1.29e-01 2.34e-01 8.03e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 1.29e-01 -2.13e-01 8.03e-01
REACTOME CELLULAR HEXOSE TRANSPORT 21 1.29e-01 -1.91e-01 8.03e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 1.30e-01 -1.72e-01 8.03e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 1.30e-01 -2.92e-01 8.03e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 1.30e-01 1.10e-01 8.03e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 1.30e-01 -2.26e-01 8.03e-01
REACTOME EICOSANOIDS 12 1.31e-01 2.52e-01 8.03e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 1.32e-01 -1.43e-01 8.03e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 1.33e-01 -1.34e-01 8.03e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 1.33e-01 -3.54e-01 8.03e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 1.33e-01 -1.53e-01 8.03e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 1.34e-01 -3.27e-01 8.03e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 1.34e-01 3.27e-01 8.03e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 1.34e-01 -8.84e-02 8.03e-01
REACTOME ATTENUATION PHASE 27 1.35e-01 -1.66e-01 8.03e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 1.36e-01 -2.30e-01 8.07e-01
REACTOME PREDNISONE ADME 10 1.38e-01 2.71e-01 8.14e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 1.39e-01 -1.71e-01 8.14e-01
REACTOME SIGNALING BY WNT 318 1.39e-01 -4.82e-02 8.14e-01
REACTOME FASL CD95L SIGNALING 5 1.41e-01 -3.80e-01 8.14e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 1.41e-01 3.80e-01 8.14e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 1.42e-01 2.06e-01 8.14e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 1.42e-01 -2.19e-01 8.14e-01
REACTOME INOSITOL PHOSPHATE METABOLISM 45 1.42e-01 -1.27e-01 8.14e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 1.42e-01 1.36e-01 8.14e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 1.42e-01 -1.81e-01 8.14e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 1.43e-01 -2.82e-01 8.14e-01
REACTOME METHYLATION 14 1.44e-01 2.26e-01 8.14e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.45e-01 -1.15e-01 8.14e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 1.45e-01 -2.34e-01 8.14e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 1.45e-01 -3.43e-01 8.14e-01
REACTOME SHC MEDIATED CASCADE FGFR4 19 1.45e-01 1.93e-01 8.14e-01
REACTOME PROLACTIN RECEPTOR SIGNALING 15 1.46e-01 -2.17e-01 8.14e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 1.47e-01 -9.33e-02 8.14e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 1.47e-01 7.67e-02 8.14e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 1.47e-01 1.06e-01 8.14e-01
REACTOME PERK REGULATES GENE EXPRESSION 31 1.48e-01 1.50e-01 8.14e-01
REACTOME ARMS MEDIATED ACTIVATION 7 1.48e-01 -3.16e-01 8.14e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 1.48e-01 -2.64e-01 8.14e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 1.49e-01 1.37e-01 8.15e-01
REACTOME SIALIC ACID METABOLISM 33 1.50e-01 -1.45e-01 8.15e-01
REACTOME PI 3K CASCADE FGFR4 19 1.50e-01 1.91e-01 8.15e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 1.51e-01 -2.08e-01 8.15e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 1.51e-01 -1.36e-01 8.15e-01
REACTOME SIGNALING BY NOTCH1 69 1.53e-01 -9.94e-02 8.25e-01
REACTOME TOLL LIKE RECEPTOR CASCADES 158 1.54e-01 -6.57e-02 8.25e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 1.54e-01 -6.11e-02 8.25e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 1.55e-01 -1.17e-01 8.28e-01
REACTOME SIGNALING BY WNT IN CANCER 32 1.58e-01 -1.44e-01 8.36e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 1.58e-01 -6.94e-02 8.36e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 1.58e-01 2.58e-01 8.36e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 1.59e-01 -1.27e-01 8.36e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 1.59e-01 1.82e-01 8.36e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 1.61e-01 -1.81e-01 8.38e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 1.61e-01 -1.65e-01 8.38e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 1.62e-01 -4.35e-02 8.41e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 1.62e-01 8.04e-02 8.41e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 1.65e-01 1.52e-01 8.51e-01
REACTOME RAB REGULATION OF TRAFFICKING 110 1.66e-01 -7.64e-02 8.52e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 1.66e-01 -1.74e-01 8.52e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 1.67e-01 8.67e-02 8.52e-01
REACTOME RND2 GTPASE CYCLE 42 1.69e-01 1.23e-01 8.52e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 1.70e-01 -2.12e-01 8.52e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 1.71e-01 -1.86e-01 8.52e-01
REACTOME PECAM1 INTERACTIONS 12 1.71e-01 -2.28e-01 8.52e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 1.73e-01 -6.82e-02 8.52e-01
REACTOME PHOSPHORYLATION OF THE APC C 20 1.73e-01 1.76e-01 8.52e-01
REACTOME MEIOTIC SYNAPSIS 73 1.73e-01 9.21e-02 8.52e-01
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 1.74e-01 3.06e-02 8.52e-01
REACTOME INTERLEUKIN 36 PATHWAY 7 1.74e-01 2.97e-01 8.52e-01
REACTOME ATORVASTATIN ADME 9 1.75e-01 2.61e-01 8.52e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 1.75e-01 -1.90e-01 8.52e-01
REACTOME REGULATION OF TP53 ACTIVITY 156 1.75e-01 -6.29e-02 8.52e-01
REACTOME GLYCOGEN STORAGE DISEASES 15 1.76e-01 2.02e-01 8.52e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 1.77e-01 -1.79e-01 8.52e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 1.77e-01 -1.95e-01 8.52e-01
REACTOME SIGNALING BY LRP5 MUTANTS 6 1.77e-01 -3.18e-01 8.52e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 1.78e-01 8.04e-02 8.52e-01
REACTOME MAPK1 ERK2 ACTIVATION 9 1.78e-01 -2.59e-01 8.52e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 1.79e-01 -8.06e-02 8.52e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 1.79e-01 3.47e-01 8.52e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 1.79e-01 -9.56e-02 8.52e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 1.80e-01 -2.34e-01 8.52e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 1.80e-01 -1.35e-01 8.52e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 1.80e-01 -2.23e-01 8.52e-01
REACTOME RET SIGNALING 40 1.80e-01 -1.22e-01 8.52e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 1.81e-01 -7.01e-02 8.52e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 1.81e-01 -1.46e-01 8.52e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 1.83e-01 1.92e-01 8.52e-01
REACTOME METABOLISM OF NUCLEOTIDES 94 1.83e-01 -7.95e-02 8.52e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 1.83e-01 -2.56e-01 8.52e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 1.83e-01 1.99e-01 8.52e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 1.84e-01 -2.15e-02 8.52e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 1.85e-01 -6.82e-02 8.52e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 1.85e-01 -2.71e-01 8.52e-01
REACTOME PEPTIDE HORMONE METABOLISM 84 1.85e-01 -8.36e-02 8.52e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 1.86e-01 -1.09e-01 8.52e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 1.86e-01 -3.42e-01 8.52e-01
REACTOME SIGNALING BY INSULIN RECEPTOR 80 1.86e-01 -8.55e-02 8.52e-01
REACTOME DIGESTION 17 1.87e-01 1.85e-01 8.52e-01
REACTOME INTERFERON ALPHA BETA SIGNALING 70 1.87e-01 9.11e-02 8.52e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 1.89e-01 -1.39e-01 8.57e-01
REACTOME REGULATION OF IFNG SIGNALING 14 1.90e-01 -2.02e-01 8.57e-01
REACTOME PYRIMIDINE CATABOLISM 12 1.90e-01 -2.18e-01 8.57e-01
REACTOME HEDGEHOG OFF STATE 111 1.91e-01 -7.19e-02 8.57e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 1.92e-01 1.22e-01 8.59e-01
REACTOME PTEN REGULATION 135 1.93e-01 -6.49e-02 8.59e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 1.93e-01 -1.94e-01 8.59e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 1.94e-01 1.68e-01 8.59e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.94e-01 -1.50e-01 8.59e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 1.94e-01 1.82e-01 8.59e-01
REACTOME REPRODUCTION 136 1.95e-01 6.44e-02 8.59e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 1.96e-01 -1.14e-01 8.59e-01
REACTOME LGI ADAM INTERACTIONS 14 1.96e-01 -2.00e-01 8.59e-01
REACTOME GLUCOSE METABOLISM 90 1.97e-01 -7.88e-02 8.59e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 1.97e-01 -1.63e-01 8.59e-01
REACTOME MET INTERACTS WITH TNS PROTEINS 5 2.00e-01 -3.31e-01 8.67e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 2.00e-01 8.08e-02 8.67e-01
REACTOME SULFUR AMINO ACID METABOLISM 27 2.00e-01 1.42e-01 8.67e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 2.01e-01 1.51e-01 8.67e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 2.01e-01 -2.23e-01 8.67e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 2.04e-01 -6.48e-02 8.69e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 2.04e-01 -1.44e-01 8.69e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 2.04e-01 -2.21e-01 8.69e-01
REACTOME G2 PHASE 5 2.05e-01 3.28e-01 8.69e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 2.05e-01 -2.59e-01 8.69e-01
REACTOME AMYLOID FIBER FORMATION 102 2.05e-01 7.27e-02 8.69e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 2.06e-01 2.98e-01 8.69e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 2.07e-01 -2.20e-01 8.69e-01
REACTOME REPRESSION OF WNT TARGET GENES 14 2.07e-01 -1.95e-01 8.69e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 2.09e-01 -2.96e-01 8.69e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 2.09e-01 -2.29e-01 8.69e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 2.09e-01 2.42e-01 8.69e-01
REACTOME CD209 DC SIGN SIGNALING 20 2.10e-01 -1.62e-01 8.69e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 2.11e-01 -9.25e-02 8.69e-01
REACTOME PYRIMIDINE SALVAGE 10 2.12e-01 -2.28e-01 8.69e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 2.13e-01 -2.54e-01 8.69e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 2.13e-01 -1.27e-01 8.69e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 2.13e-01 -9.89e-02 8.69e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 2.13e-01 -7.90e-02 8.69e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 2.14e-01 -1.65e-01 8.69e-01
REACTOME RND3 GTPASE CYCLE 41 2.14e-01 1.12e-01 8.69e-01
REACTOME REGULATION BY C FLIP 11 2.15e-01 -2.16e-01 8.69e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 2.15e-01 7.57e-02 8.69e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 2.15e-01 -2.71e-01 8.69e-01
REACTOME TRNA AMINOACYLATION 40 2.15e-01 1.13e-01 8.69e-01
REACTOME VITAMIN C ASCORBATE METABOLISM 8 2.15e-01 -2.53e-01 8.69e-01
REACTOME RHOT1 GTPASE CYCLE 5 2.17e-01 3.19e-01 8.70e-01
REACTOME RAS PROCESSING 22 2.18e-01 1.52e-01 8.70e-01
REACTOME DISEASES OF METABOLISM 237 2.19e-01 4.64e-02 8.70e-01
REACTOME G0 AND EARLY G1 27 2.19e-01 1.37e-01 8.70e-01
REACTOME NUCLEOTIDE EXCISION REPAIR 107 2.20e-01 -6.87e-02 8.70e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 2.20e-01 -1.06e-01 8.70e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 2.20e-01 -4.12e-02 8.70e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 2.21e-01 -1.58e-01 8.70e-01
REACTOME REGULATION OF SIGNALING BY CBL 22 2.21e-01 -1.51e-01 8.70e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 2.21e-01 -2.67e-01 8.70e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 2.23e-01 2.66e-01 8.70e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 2.25e-01 1.14e-01 8.70e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 2.25e-01 -2.86e-01 8.70e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 2.26e-01 -2.02e-01 8.70e-01
REACTOME SNRNP ASSEMBLY 53 2.26e-01 9.62e-02 8.70e-01
REACTOME NEUROFASCIN INTERACTIONS 6 2.26e-01 2.86e-01 8.70e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 2.26e-01 -1.12e-01 8.70e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 2.27e-01 2.11e-01 8.70e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 2.27e-01 -2.01e-01 8.70e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 2.27e-01 6.58e-02 8.70e-01
REACTOME HEME SIGNALING 47 2.28e-01 -1.02e-01 8.70e-01
REACTOME HCMV INFECTION 152 2.28e-01 5.66e-02 8.70e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 2.29e-01 2.10e-01 8.70e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 2.29e-01 -1.59e-01 8.70e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 2.29e-01 1.27e-01 8.70e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 2.30e-01 1.59e-01 8.70e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 2.31e-01 1.73e-01 8.70e-01
REACTOME RHOBTB GTPASE CYCLE 34 2.32e-01 -1.18e-01 8.70e-01
REACTOME TRANSLATION 278 2.32e-01 4.16e-02 8.70e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 2.33e-01 -2.30e-01 8.70e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 2.33e-01 -1.99e-01 8.70e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 2.34e-01 -1.47e-01 8.70e-01
REACTOME LONG TERM POTENTIATION 22 2.34e-01 -1.47e-01 8.70e-01
REACTOME RAP1 SIGNALLING 16 2.34e-01 -1.72e-01 8.70e-01
REACTOME NCAM1 INTERACTIONS 41 2.34e-01 -1.07e-01 8.70e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 2.35e-01 -7.78e-02 8.70e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 2.35e-01 -1.50e-01 8.70e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 2.36e-01 -1.25e-01 8.71e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 2.37e-01 -7.85e-02 8.71e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 2.37e-01 1.89e-01 8.71e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 2.38e-01 1.42e-01 8.71e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 2.38e-01 -2.05e-01 8.71e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 2.39e-01 8.86e-02 8.71e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 2.39e-01 -8.32e-02 8.71e-01
REACTOME ADAPTIVE IMMUNE SYSTEM 729 2.40e-01 -2.56e-02 8.72e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 2.41e-01 2.76e-01 8.73e-01
REACTOME ANDROGEN BIOSYNTHESIS 11 2.41e-01 2.04e-01 8.73e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 2.43e-01 -1.44e-01 8.73e-01
REACTOME MITOCHONDRIAL BIOGENESIS 87 2.44e-01 -7.22e-02 8.73e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 2.45e-01 -6.12e-02 8.73e-01
REACTOME SIGNAL AMPLIFICATION 33 2.45e-01 -1.17e-01 8.73e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 2.46e-01 -7.81e-02 8.73e-01
REACTOME ORGANIC ANION TRANSPORT 5 2.46e-01 3.00e-01 8.73e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 2.46e-01 6.58e-02 8.73e-01
REACTOME UCH PROTEINASES 99 2.46e-01 -6.75e-02 8.73e-01
REACTOME PLASMA LIPOPROTEIN REMODELING 33 2.46e-01 -1.17e-01 8.73e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 2.48e-01 -2.98e-01 8.79e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 2.50e-01 -1.28e-01 8.81e-01
REACTOME REGULATION OF INSULIN SECRETION 77 2.50e-01 -7.58e-02 8.81e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 2.50e-01 -1.11e-01 8.81e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 2.51e-01 -2.34e-01 8.81e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 2.52e-01 1.38e-01 8.83e-01
REACTOME SUPPRESSION OF APOPTOSIS 7 2.55e-01 -2.48e-01 8.83e-01
REACTOME FATTY ACID METABOLISM 170 2.56e-01 -5.05e-02 8.83e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 2.58e-01 1.50e-01 8.83e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 2.59e-01 2.91e-01 8.83e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 2.59e-01 -2.06e-01 8.83e-01
REACTOME SIGNALING BY NOTCH2 32 2.60e-01 -1.15e-01 8.83e-01
REACTOME VASOPRESSIN LIKE RECEPTORS 5 2.60e-01 -2.91e-01 8.83e-01
REACTOME CREATINE METABOLISM 9 2.61e-01 2.17e-01 8.83e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 2.62e-01 -6.49e-02 8.83e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 2.63e-01 -2.28e-01 8.83e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 2.63e-01 1.12e-01 8.83e-01
REACTOME P75NTR REGULATES AXONOGENESIS 9 2.64e-01 -2.15e-01 8.83e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 2.64e-01 -1.56e-01 8.83e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 2.65e-01 -2.43e-01 8.83e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 2.67e-01 1.93e-01 8.83e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 2.67e-01 -1.66e-01 8.83e-01
REACTOME RHO GTPASES ACTIVATE PAKS 19 2.67e-01 1.47e-01 8.83e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 2.67e-01 -6.45e-02 8.83e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 2.68e-01 2.61e-01 8.83e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 2.69e-01 -7.34e-02 8.83e-01
REACTOME NEF AND SIGNAL TRANSDUCTION 8 2.69e-01 -2.26e-01 8.83e-01
REACTOME SHC MEDIATED CASCADE FGFR3 17 2.70e-01 1.55e-01 8.83e-01
REACTOME RHOB GTPASE CYCLE 67 2.70e-01 -7.79e-02 8.83e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 2.70e-01 -1.70e-01 8.83e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 2.70e-01 -4.05e-02 8.83e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 2.72e-01 -2.01e-01 8.83e-01
REACTOME COMPLEX I BIOGENESIS 49 2.73e-01 -9.05e-02 8.83e-01
REACTOME MICRORNA MIRNA BIOGENESIS 25 2.73e-01 -1.27e-01 8.83e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 2.74e-01 -1.09e-01 8.83e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 2.74e-01 -7.91e-02 8.83e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 2.74e-01 2.24e-01 8.83e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 2.74e-01 -1.49e-01 8.83e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 2.75e-01 7.89e-02 8.83e-01
REACTOME DEUBIQUITINATION 260 2.75e-01 -3.93e-02 8.83e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 2.75e-01 -1.99e-01 8.83e-01
REACTOME DARPP 32 EVENTS 24 2.76e-01 -1.28e-01 8.83e-01
REACTOME DEGRADATION OF DVL 56 2.76e-01 -8.41e-02 8.83e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 2.76e-01 -2.09e-01 8.83e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 2.77e-01 1.81e-01 8.83e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 2.78e-01 -1.18e-01 8.83e-01
REACTOME PI 3K CASCADE FGFR3 17 2.78e-01 1.52e-01 8.83e-01
REACTOME M PHASE 398 2.79e-01 3.16e-02 8.83e-01
REACTOME RHOC GTPASE CYCLE 71 2.79e-01 -7.43e-02 8.83e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 2.80e-01 -2.55e-01 8.83e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 2.80e-01 8.27e-02 8.83e-01
REACTOME SIGNALING BY PDGF 57 2.80e-01 -8.27e-02 8.83e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 2.82e-01 -1.96e-01 8.83e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 2.83e-01 7.65e-02 8.83e-01
REACTOME HEMOSTASIS 591 2.83e-01 -2.59e-02 8.83e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 2.83e-01 -2.34e-01 8.83e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 2.83e-01 1.50e-01 8.83e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 2.84e-01 6.14e-02 8.83e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 2.84e-01 -1.08e-01 8.83e-01
REACTOME MATURATION OF PROTEIN 3A 9 2.84e-01 -2.06e-01 8.83e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 2.84e-01 9.13e-02 8.83e-01
REACTOME ETHANOL OXIDATION 12 2.85e-01 1.78e-01 8.83e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 2.85e-01 -1.09e-01 8.83e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 2.85e-01 -9.31e-02 8.83e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 2.86e-01 1.23e-01 8.83e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 2.86e-01 -2.51e-01 8.83e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 2.87e-01 9.49e-02 8.83e-01
REACTOME CELL CELL COMMUNICATION 126 2.87e-01 -5.49e-02 8.83e-01
REACTOME MET ACTIVATES PTK2 SIGNALING 30 2.88e-01 1.12e-01 8.83e-01
REACTOME CYP2E1 REACTIONS 10 2.88e-01 1.94e-01 8.83e-01
REACTOME SIGNALING BY BMP 27 2.88e-01 -1.18e-01 8.83e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 2.88e-01 -9.95e-02 8.83e-01
REACTOME ANTIMICROBIAL PEPTIDES 76 2.89e-01 7.04e-02 8.83e-01
REACTOME UNWINDING OF DNA 12 2.89e-01 -1.77e-01 8.83e-01
REACTOME RECYCLING OF EIF2 GDP 7 2.89e-01 2.31e-01 8.83e-01
REACTOME COENZYME A BIOSYNTHESIS 8 2.90e-01 -2.16e-01 8.83e-01
REACTOME COLLAGEN DEGRADATION 61 2.93e-01 -7.79e-02 8.87e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 2.93e-01 -1.15e-01 8.87e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 2.93e-01 -8.68e-02 8.87e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 2.93e-01 2.71e-01 8.87e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 2.95e-01 -1.56e-01 8.89e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 2.96e-01 -1.10e-01 8.91e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 2.96e-01 7.44e-02 8.91e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 2.98e-01 -1.90e-01 8.91e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 3.00e-01 1.45e-01 8.91e-01
REACTOME METHIONINE SALVAGE PATHWAY 6 3.01e-01 2.44e-01 8.91e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 3.01e-01 -1.11e-01 8.91e-01
REACTOME SIGNALING BY NOTCH3 48 3.01e-01 -8.63e-02 8.91e-01
REACTOME GDP FUCOSE BIOSYNTHESIS 6 3.01e-01 -2.44e-01 8.91e-01
REACTOME JOSEPHIN DOMAIN DUBS 11 3.03e-01 1.79e-01 8.91e-01
REACTOME INTERLEUKIN 9 SIGNALING 7 3.03e-01 -2.25e-01 8.91e-01
REACTOME ATTACHMENT AND ENTRY 16 3.03e-01 1.49e-01 8.91e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 3.03e-01 -1.59e-01 8.91e-01
REACTOME MUSCLE CONTRACTION 197 3.04e-01 -4.25e-02 8.91e-01
REACTOME SEPARATION OF SISTER CHROMATIDS 184 3.04e-01 4.39e-02 8.91e-01
REACTOME DUAL INCISION IN TC NER 63 3.04e-01 -7.49e-02 8.91e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 3.05e-01 -1.36e-01 8.91e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 3.05e-01 -1.06e-01 8.91e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 3.06e-01 6.50e-02 8.91e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 3.08e-01 -1.18e-01 8.91e-01
REACTOME HCMV EARLY EVENTS 128 3.08e-01 5.21e-02 8.91e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 3.09e-01 -1.96e-01 8.91e-01
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 3.09e-01 1.57e-01 8.91e-01
REACTOME MTOR SIGNALLING 40 3.10e-01 -9.27e-02 8.91e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 3.10e-01 -1.51e-01 8.91e-01
REACTOME EGFR DOWNREGULATION 30 3.10e-01 -1.07e-01 8.91e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 3.11e-01 -2.62e-01 8.91e-01
REACTOME SIGNALING BY MET 78 3.11e-01 -6.63e-02 8.91e-01
REACTOME MET RECEPTOR RECYCLING 10 3.12e-01 -1.85e-01 8.91e-01
REACTOME HIV TRANSCRIPTION ELONGATION 42 3.13e-01 9.00e-02 8.91e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 3.13e-01 -6.40e-02 8.91e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 3.14e-01 -1.94e-01 8.91e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 3.14e-01 -2.37e-01 8.91e-01
REACTOME SARS COV 2 HOST INTERACTIONS 191 3.14e-01 4.22e-02 8.91e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 3.15e-01 -5.65e-02 8.91e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 3.15e-01 -1.30e-01 8.91e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 3.17e-01 -9.26e-02 8.91e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 3.17e-01 1.83e-01 8.91e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 3.19e-01 -5.12e-02 8.91e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 3.19e-01 1.66e-01 8.91e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 3.20e-01 -2.35e-01 8.91e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 3.20e-01 -2.17e-01 8.91e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 3.20e-01 -1.59e-01 8.91e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 3.21e-01 2.03e-01 8.91e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 3.22e-01 -2.16e-01 8.91e-01
REACTOME MAP2K AND MAPK ACTIVATION 38 3.22e-01 -9.28e-02 8.91e-01
REACTOME RHO GTPASES ACTIVATE FORMINS 136 3.22e-01 4.92e-02 8.91e-01
REACTOME FIBRONECTIN MATRIX FORMATION 6 3.22e-01 -2.33e-01 8.91e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 3.23e-01 2.02e-01 8.91e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 3.23e-01 -6.00e-02 8.91e-01
REACTOME LINOLEIC ACID LA METABOLISM 7 3.23e-01 -2.16e-01 8.91e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 3.23e-01 2.16e-01 8.91e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 3.24e-01 -2.33e-01 8.91e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 3.24e-01 -2.55e-01 8.91e-01
REACTOME METABOLISM OF PORPHYRINS 26 3.25e-01 1.12e-01 8.91e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 3.26e-01 -1.14e-01 8.92e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 3.26e-01 -2.14e-01 8.92e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 3.26e-01 -6.23e-02 8.92e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 3.28e-01 5.35e-02 8.93e-01
REACTOME SYNTHESIS OF PA 38 3.28e-01 -9.17e-02 8.93e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 3.29e-01 -1.88e-01 8.96e-01
REACTOME PI5P REGULATES TP53 ACETYLATION 9 3.31e-01 1.87e-01 8.97e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 3.32e-01 -5.89e-02 8.97e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 3.32e-01 -1.04e-01 8.97e-01
REACTOME PHOSPHORYLATION OF EMI1 6 3.32e-01 2.29e-01 8.97e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 3.33e-01 -1.61e-01 8.97e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 3.34e-01 -5.92e-02 8.97e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 3.34e-01 -1.97e-01 8.97e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 3.36e-01 -1.28e-01 8.97e-01
REACTOME TRYPTOPHAN CATABOLISM 14 3.36e-01 1.49e-01 8.97e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 3.36e-01 -2.48e-01 8.97e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 3.37e-01 -3.32e-02 8.97e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 3.39e-01 2.09e-01 8.97e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 3.39e-01 -9.61e-02 8.97e-01
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 3.40e-01 1.01e-01 8.97e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 3.40e-01 -2.25e-01 8.97e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 3.40e-01 -1.66e-01 8.97e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 3.42e-01 1.66e-01 8.97e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 3.42e-01 2.08e-01 8.97e-01
REACTOME INTEGRATION OF PROVIRUS 9 3.42e-01 1.83e-01 8.97e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 3.42e-01 -7.21e-02 8.97e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 3.42e-01 1.83e-01 8.97e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 3.42e-01 1.12e-01 8.97e-01
REACTOME INTERLEUKIN 17 SIGNALING 66 3.42e-01 -6.76e-02 8.97e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 3.44e-01 -2.23e-01 8.98e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 3.45e-01 9.50e-02 8.98e-01
REACTOME MISCELLANEOUS SUBSTRATES 12 3.45e-01 1.57e-01 8.98e-01
REACTOME SENSORY PERCEPTION OF TASTE 47 3.45e-01 7.95e-02 8.98e-01
REACTOME ARACHIDONIC ACID METABOLISM 57 3.49e-01 -7.18e-02 8.98e-01
REACTOME PEXOPHAGY 11 3.49e-01 -1.63e-01 8.98e-01
REACTOME DOPAMINE RECEPTORS 5 3.50e-01 -2.41e-01 8.98e-01
REACTOME PLATELET HOMEOSTASIS 85 3.50e-01 -5.86e-02 8.98e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 3.51e-01 -7.48e-02 8.98e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 3.51e-01 -6.11e-02 8.98e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 3.51e-01 -1.17e-01 8.98e-01
REACTOME LYSINE CATABOLISM 12 3.52e-01 1.55e-01 8.98e-01
REACTOME SARS COV 1 INFECTION 136 3.52e-01 -4.62e-02 8.98e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 3.52e-01 -2.40e-01 8.98e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 3.52e-01 -2.03e-01 8.98e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 3.53e-01 1.43e-01 8.98e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 3.54e-01 -1.89e-01 8.98e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 3.54e-01 1.89e-01 8.98e-01
REACTOME INTERLEUKIN 27 SIGNALING 11 3.55e-01 -1.61e-01 8.98e-01
REACTOME INACTIVATION OF CDC42 AND RAC1 8 3.55e-01 -1.89e-01 8.98e-01
REACTOME TRAIL SIGNALING 8 3.55e-01 -1.89e-01 8.98e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 3.55e-01 -1.61e-01 8.98e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 3.55e-01 -1.29e-01 8.98e-01
REACTOME DISEASES OF GLYCOSYLATION 137 3.57e-01 4.56e-02 8.98e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 3.57e-01 -1.77e-01 8.98e-01
REACTOME ACYL CHAIN REMODELING OF CL 5 3.58e-01 2.37e-01 8.98e-01
REACTOME CHYLOMICRON REMODELING 10 3.58e-01 -1.68e-01 8.98e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 3.59e-01 2.37e-01 8.98e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 3.59e-01 1.77e-01 8.98e-01
REACTOME KEAP1 NFE2L2 PATHWAY 104 3.61e-01 -5.19e-02 9.01e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 3.62e-01 8.91e-02 9.01e-01
REACTOME THYROXINE BIOSYNTHESIS 10 3.62e-01 1.67e-01 9.01e-01
REACTOME RAF ACTIVATION 33 3.63e-01 -9.14e-02 9.04e-01
REACTOME MRNA CAPPING 28 3.64e-01 9.90e-02 9.04e-01
REACTOME RHO GTPASES ACTIVATE KTN1 11 3.65e-01 -1.58e-01 9.04e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 3.65e-01 -5.55e-02 9.04e-01
REACTOME DEGRADATION OF AXIN 54 3.67e-01 -7.10e-02 9.04e-01
REACTOME ERK MAPK TARGETS 20 3.67e-01 -1.17e-01 9.04e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 3.68e-01 -1.09e-01 9.04e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 3.68e-01 -1.97e-01 9.04e-01
REACTOME PURINE SALVAGE 12 3.68e-01 1.50e-01 9.04e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 3.70e-01 -8.52e-02 9.05e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 3.70e-01 1.22e-01 9.05e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 3.71e-01 -1.38e-01 9.05e-01
REACTOME BASE EXCISION REPAIR 87 3.71e-01 5.54e-02 9.05e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 3.72e-01 -6.97e-02 9.05e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 3.73e-01 2.10e-01 9.05e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 3.73e-01 -1.63e-01 9.05e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 3.73e-01 -1.29e-01 9.05e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 3.74e-01 -3.41e-02 9.07e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 3.76e-01 1.71e-01 9.07e-01
REACTOME LDL REMODELING 6 3.76e-01 -2.09e-01 9.07e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 3.77e-01 1.47e-01 9.07e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 3.78e-01 8.61e-02 9.07e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 3.78e-01 3.39e-02 9.07e-01
REACTOME EPH EPHRIN SIGNALING 90 3.79e-01 -5.37e-02 9.07e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 3.80e-01 -7.75e-02 9.07e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 3.80e-01 1.92e-01 9.07e-01
REACTOME CELL CYCLE MITOTIC 539 3.81e-01 2.21e-02 9.07e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 3.81e-01 6.83e-02 9.07e-01
REACTOME RHOBTB1 GTPASE CYCLE 22 3.82e-01 -1.08e-01 9.07e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 3.82e-01 -1.30e-01 9.07e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 3.82e-01 -8.43e-02 9.07e-01
REACTOME SIGNALING BY CSF3 G CSF 30 3.82e-01 -9.23e-02 9.07e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 3.84e-01 -7.77e-02 9.07e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 3.85e-01 -7.66e-02 9.07e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 3.85e-01 4.50e-02 9.07e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 3.85e-01 2.05e-01 9.07e-01
REACTOME INDUCTION OF CELL CELL FUSION 12 3.86e-01 -1.44e-01 9.07e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 3.87e-01 -1.67e-01 9.07e-01
REACTOME L1CAM INTERACTIONS 112 3.87e-01 -4.73e-02 9.07e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 3.88e-01 -1.09e-01 9.07e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 3.88e-01 -1.25e-01 9.07e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 3.89e-01 -1.06e-01 9.07e-01
REACTOME SIGNALLING TO ERKS 34 3.89e-01 -8.54e-02 9.07e-01
REACTOME ACYL CHAIN REMODELLING OF PG 18 3.90e-01 -1.17e-01 9.07e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 3.91e-01 1.37e-01 9.07e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 3.92e-01 -9.71e-02 9.07e-01
REACTOME SIGNALING BY PTK6 54 3.92e-01 -6.74e-02 9.07e-01
REACTOME PEROXISOMAL LIPID METABOLISM 28 3.92e-01 -9.34e-02 9.07e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 3.93e-01 -4.88e-02 9.07e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 3.95e-01 -8.19e-02 9.07e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 3.95e-01 -5.53e-02 9.07e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 3.96e-01 -1.73e-01 9.07e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 3.97e-01 -1.07e-01 9.07e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 3.97e-01 8.39e-02 9.07e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 3.98e-01 6.26e-02 9.07e-01
REACTOME CELL JUNCTION ORGANIZATION 89 3.98e-01 -5.19e-02 9.07e-01
REACTOME LIPOPHAGY 9 3.98e-01 -1.63e-01 9.07e-01
REACTOME PARASITE INFECTION 57 3.98e-01 -6.47e-02 9.07e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 4.00e-01 4.76e-02 9.07e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 4.02e-01 -2.17e-01 9.07e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 4.02e-01 -1.17e-01 9.07e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 4.03e-01 -6.30e-02 9.07e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 4.04e-01 -2.16e-01 9.07e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 4.04e-01 1.97e-01 9.07e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 4.04e-01 -9.28e-02 9.07e-01
REACTOME SIGNALING BY ERYTHROPOIETIN 25 4.04e-01 -9.64e-02 9.07e-01
REACTOME RHOA GTPASE CYCLE 142 4.05e-01 -4.05e-02 9.07e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 4.06e-01 -1.81e-01 9.07e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 4.07e-01 -7.78e-02 9.07e-01
REACTOME RHOBTB3 ATPASE CYCLE 8 4.07e-01 -1.69e-01 9.07e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 4.08e-01 2.56e-02 9.07e-01
REACTOME SIGNALING BY NOTCH4 80 4.08e-01 -5.35e-02 9.07e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 4.09e-01 -1.27e-01 9.07e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 4.10e-01 -4.82e-02 9.07e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 4.10e-01 -1.01e-01 9.07e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 4.10e-01 -2.13e-01 9.07e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 4.11e-01 1.50e-01 9.07e-01
REACTOME PI METABOLISM 79 4.11e-01 -5.35e-02 9.07e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 4.12e-01 -1.18e-01 9.07e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 4.13e-01 -1.67e-01 9.07e-01
REACTOME NUCLEAR SIGNALING BY ERBB4 32 4.14e-01 -8.35e-02 9.07e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 4.15e-01 5.06e-02 9.07e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 4.16e-01 -3.35e-02 9.07e-01
REACTOME DNA DAMAGE BYPASS 47 4.16e-01 -6.86e-02 9.07e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 4.16e-01 4.28e-02 9.07e-01
REACTOME XENOBIOTICS 22 4.16e-01 1.00e-01 9.07e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 4.17e-01 -1.30e-01 9.07e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 4.17e-01 -7.51e-02 9.07e-01
REACTOME MITOTIC G2 G2 M PHASES 194 4.17e-01 -3.38e-02 9.07e-01
REACTOME PYRUVATE METABOLISM 29 4.18e-01 -8.70e-02 9.07e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 4.18e-01 1.10e-01 9.07e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 4.18e-01 -2.09e-01 9.07e-01
REACTOME MRNA SPLICING MINOR PATHWAY 49 4.19e-01 6.68e-02 9.07e-01
REACTOME INTEGRIN SIGNALING 27 4.19e-01 -8.99e-02 9.07e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 4.19e-01 -4.83e-02 9.07e-01
REACTOME CA2 ACTIVATED K CHANNELS 9 4.19e-01 -1.56e-01 9.07e-01
REACTOME ACYL CHAIN REMODELLING OF PS 22 4.19e-01 -9.95e-02 9.07e-01
REACTOME LYSOSOME VESICLE BIOGENESIS 33 4.20e-01 -8.12e-02 9.07e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 4.21e-01 -1.64e-01 9.07e-01
REACTOME BICARBONATE TRANSPORTERS 10 4.21e-01 1.47e-01 9.07e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 4.21e-01 -3.04e-02 9.07e-01
REACTOME MET ACTIVATES RAP1 AND RAC1 11 4.22e-01 -1.40e-01 9.07e-01
REACTOME MRNA EDITING C TO U CONVERSION 8 4.23e-01 -1.64e-01 9.07e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 4.23e-01 5.28e-02 9.07e-01
REACTOME ORGANIC ANION TRANSPORTERS 10 4.24e-01 1.46e-01 9.07e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 4.25e-01 1.88e-01 9.07e-01
REACTOME ABC TRANSPORTER DISORDERS 76 4.25e-01 -5.29e-02 9.07e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 4.26e-01 1.23e-01 9.07e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 4.27e-01 -5.11e-02 9.07e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 4.27e-01 -3.74e-02 9.07e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 4.27e-01 -8.52e-02 9.07e-01
REACTOME MYOGENESIS 29 4.28e-01 8.51e-02 9.07e-01
REACTOME INTERLEUKIN 12 SIGNALING 43 4.28e-01 6.98e-02 9.07e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 4.30e-01 4.61e-02 9.07e-01
REACTOME CRMPS IN SEMA3A SIGNALING 15 4.30e-01 1.18e-01 9.07e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 4.31e-01 -2.04e-01 9.07e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 4.31e-01 -4.20e-02 9.07e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 4.31e-01 1.31e-01 9.07e-01
REACTOME RRNA PROCESSING 192 4.32e-01 3.29e-02 9.07e-01
REACTOME ACYL CHAIN REMODELLING OF PC 27 4.32e-01 -8.73e-02 9.07e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 4.32e-01 -8.73e-02 9.07e-01
REACTOME TELOMERE MAINTENANCE 106 4.34e-01 4.40e-02 9.07e-01
REACTOME INTERLEUKIN 15 SIGNALING 13 4.34e-01 -1.25e-01 9.07e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 4.35e-01 -9.03e-02 9.07e-01
REACTOME CGMP EFFECTS 16 4.35e-01 1.13e-01 9.07e-01
REACTOME HS GAG BIOSYNTHESIS 28 4.35e-01 8.52e-02 9.07e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 4.36e-01 -7.04e-02 9.07e-01
REACTOME AURKA ACTIVATION BY TPX2 69 4.36e-01 -5.42e-02 9.07e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 4.36e-01 -8.21e-02 9.07e-01
REACTOME HYALURONAN METABOLISM 17 4.37e-01 -1.09e-01 9.07e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 4.38e-01 6.34e-02 9.07e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 4.39e-01 9.54e-02 9.07e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 4.40e-01 -4.50e-02 9.07e-01
REACTOME MRNA EDITING 10 4.40e-01 -1.41e-01 9.07e-01
REACTOME RAC1 GTPASE CYCLE 172 4.40e-01 -3.41e-02 9.07e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 4.41e-01 8.00e-02 9.07e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 4.41e-01 1.15e-01 9.07e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 4.41e-01 -1.28e-01 9.07e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 4.41e-01 -1.15e-01 9.07e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 4.42e-01 -9.25e-02 9.07e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 4.43e-01 5.93e-02 9.07e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 4.43e-01 -6.54e-02 9.07e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 4.44e-01 8.21e-02 9.07e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 4.44e-01 -9.88e-02 9.07e-01
REACTOME PURINE CATABOLISM 17 4.45e-01 -1.07e-01 9.07e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 4.46e-01 1.22e-01 9.07e-01
REACTOME SURFACTANT METABOLISM 28 4.46e-01 -8.31e-02 9.07e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 4.47e-01 -1.96e-01 9.07e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 4.47e-01 6.10e-02 9.07e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 4.47e-01 1.46e-01 9.07e-01
REACTOME PLATELET SENSITIZATION BY LDL 17 4.49e-01 -1.06e-01 9.09e-01
REACTOME COMPLEMENT CASCADE 54 4.49e-01 5.95e-02 9.09e-01
REACTOME REGULATION OF SIGNALING BY NODAL 9 4.50e-01 -1.45e-01 9.09e-01
REACTOME NICOTINAMIDE SALVAGING 19 4.50e-01 -1.00e-01 9.09e-01
REACTOME TRP CHANNELS 27 4.51e-01 8.39e-02 9.09e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 4.53e-01 4.58e-02 9.09e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 4.53e-01 -1.31e-01 9.09e-01
REACTOME CELLULAR RESPONSE TO STARVATION 147 4.54e-01 3.58e-02 9.09e-01
REACTOME G2 M CHECKPOINTS 162 4.54e-01 3.41e-02 9.09e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 4.54e-01 -1.30e-01 9.09e-01
REACTOME RESPONSE TO METAL IONS 14 4.55e-01 -1.15e-01 9.09e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 4.55e-01 4.71e-02 9.09e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 4.56e-01 -8.45e-02 9.09e-01
REACTOME SIGNALING BY EGFR 49 4.56e-01 -6.16e-02 9.09e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 4.59e-01 1.91e-01 9.09e-01
REACTOME LIPID PARTICLE ORGANIZATION 6 4.59e-01 -1.75e-01 9.09e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 4.61e-01 -1.74e-01 9.09e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 4.61e-01 -7.20e-02 9.09e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 4.62e-01 -5.96e-02 9.09e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 4.62e-01 -9.27e-02 9.09e-01
REACTOME OAS ANTIVIRAL RESPONSE 8 4.62e-01 1.50e-01 9.09e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 4.63e-01 1.34e-01 9.09e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 4.63e-01 -8.65e-02 9.09e-01
REACTOME MAPK6 MAPK4 SIGNALING 91 4.63e-01 -4.45e-02 9.09e-01
REACTOME MIRO GTPASE CYCLE 8 4.63e-01 1.50e-01 9.09e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 4.64e-01 1.50e-01 9.09e-01
REACTOME NETRIN 1 SIGNALING 49 4.64e-01 6.05e-02 9.09e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 4.65e-01 -1.17e-01 9.09e-01
REACTOME SIGNALING BY RNF43 MUTANTS 8 4.65e-01 -1.49e-01 9.09e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 4.65e-01 -4.23e-02 9.09e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 4.65e-01 1.05e-01 9.09e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 4.66e-01 -9.65e-02 9.09e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 4.66e-01 -1.72e-01 9.09e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 4.67e-01 6.07e-02 9.09e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 4.67e-01 1.02e-01 9.09e-01
REACTOME NEGATIVE REGULATION OF FLT3 15 4.69e-01 -1.08e-01 9.11e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 4.70e-01 7.89e-02 9.12e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 4.71e-01 -1.86e-01 9.12e-01
REACTOME VISUAL PHOTOTRANSDUCTION 93 4.72e-01 -4.31e-02 9.12e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 4.73e-01 -1.04e-01 9.12e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 4.73e-01 -1.85e-01 9.12e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 4.73e-01 7.33e-02 9.12e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 4.73e-01 -1.25e-01 9.12e-01
REACTOME DEFECTIVE F9 ACTIVATION 5 4.74e-01 1.85e-01 9.13e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 4.75e-01 -5.62e-02 9.13e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 4.76e-01 3.94e-02 9.13e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 4.76e-01 -6.86e-02 9.13e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 4.76e-01 -7.64e-02 9.13e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 4.78e-01 -2.76e-02 9.14e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 4.79e-01 1.29e-01 9.14e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 4.80e-01 -1.83e-01 9.14e-01
REACTOME SIGNALING BY LEPTIN 11 4.80e-01 -1.23e-01 9.14e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 4.80e-01 -3.38e-02 9.14e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 4.81e-01 8.31e-02 9.14e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 4.81e-01 7.08e-02 9.14e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 4.82e-01 -1.17e-01 9.14e-01
REACTOME SIGNALING BY ALK IN CANCER 53 4.83e-01 -5.57e-02 9.14e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 4.84e-01 -6.31e-02 9.14e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 4.85e-01 -1.22e-01 9.14e-01
REACTOME INWARDLY RECTIFYING K CHANNELS 35 4.85e-01 -6.82e-02 9.14e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 4.85e-01 5.76e-02 9.14e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 4.85e-01 7.76e-02 9.14e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 4.86e-01 -8.22e-02 9.14e-01
REACTOME SIGNALING BY FGFR2 IIIA TM 19 4.86e-01 9.24e-02 9.14e-01
REACTOME METABOLISM OF FOLATE AND PTERINES 17 4.87e-01 -9.73e-02 9.14e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 4.88e-01 -9.20e-02 9.14e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 4.88e-01 1.79e-01 9.14e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 4.88e-01 -7.56e-02 9.14e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 4.89e-01 -4.20e-02 9.14e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 4.90e-01 -9.15e-02 9.14e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 4.91e-01 -1.06e-01 9.14e-01
REACTOME SIGNALING BY ALK 26 4.91e-01 -7.81e-02 9.14e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 4.92e-01 -7.25e-02 9.15e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 4.93e-01 -6.19e-02 9.15e-01
REACTOME PTK6 REGULATES CELL CYCLE 6 4.96e-01 1.61e-01 9.15e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 4.96e-01 6.56e-02 9.15e-01
REACTOME KETONE BODY METABOLISM 9 4.96e-01 -1.31e-01 9.15e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 4.97e-01 9.01e-02 9.15e-01
REACTOME PCP CE PATHWAY 91 4.97e-01 -4.12e-02 9.15e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 4.98e-01 -4.56e-02 9.15e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 4.98e-01 -1.08e-01 9.15e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 4.99e-01 -1.24e-01 9.15e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 4.99e-01 1.18e-01 9.15e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 4.99e-01 -9.46e-02 9.15e-01
REACTOME INTERLEUKIN 6 SIGNALING 11 5.00e-01 -1.18e-01 9.15e-01
REACTOME TRIGLYCERIDE METABOLISM 35 5.00e-01 -6.59e-02 9.15e-01
REACTOME REGULATED NECROSIS 57 5.00e-01 -5.17e-02 9.15e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 5.00e-01 -7.79e-02 9.15e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 5.01e-01 -1.37e-01 9.15e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 5.01e-01 -9.43e-02 9.15e-01
REACTOME SIGNAL TRANSDUCTION BY L1 20 5.02e-01 -8.67e-02 9.15e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 5.02e-01 -8.89e-02 9.15e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 5.03e-01 -1.46e-01 9.15e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 5.04e-01 1.46e-01 9.15e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 5.05e-01 -8.41e-02 9.15e-01
REACTOME INTERLEUKIN 7 SIGNALING 31 5.05e-01 6.91e-02 9.15e-01
REACTOME IRAK4 DEFICIENCY TLR2 4 17 5.06e-01 -9.33e-02 9.15e-01
REACTOME VXPX CARGO TARGETING TO CILIUM 20 5.06e-01 -8.60e-02 9.15e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 5.07e-01 -1.28e-01 9.17e-01
REACTOME LAMININ INTERACTIONS 28 5.09e-01 -7.21e-02 9.18e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 5.09e-01 -1.10e-01 9.18e-01
REACTOME ION CHANNEL TRANSPORT 172 5.10e-01 -2.91e-02 9.18e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 5.10e-01 1.02e-01 9.18e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 5.11e-01 -4.95e-02 9.18e-01
REACTOME NOD1 2 SIGNALING PATHWAY 33 5.13e-01 6.57e-02 9.18e-01
REACTOME CTLA4 INHIBITORY SIGNALING 21 5.14e-01 -8.23e-02 9.18e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 5.14e-01 9.43e-02 9.18e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 5.14e-01 9.42e-02 9.18e-01
REACTOME AZATHIOPRINE ADME 22 5.14e-01 8.03e-02 9.18e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 5.15e-01 -1.13e-01 9.18e-01
REACTOME DISEASES OF DNA REPAIR 51 5.15e-01 -5.26e-02 9.18e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 5.16e-01 -7.50e-02 9.18e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 5.17e-01 -1.67e-01 9.18e-01
REACTOME RELAXIN RECEPTORS 8 5.19e-01 1.32e-01 9.18e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 5.20e-01 -6.91e-02 9.18e-01
REACTOME FOXO MEDIATED TRANSCRIPTION 65 5.20e-01 -4.61e-02 9.18e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 5.20e-01 -5.48e-02 9.18e-01
REACTOME PI3K AKT SIGNALING IN CANCER 103 5.21e-01 -3.66e-02 9.18e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 5.21e-01 -2.73e-02 9.18e-01
REACTOME SIGNALING BY VEGF 102 5.22e-01 -3.67e-02 9.18e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 5.22e-01 -5.71e-02 9.18e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 5.22e-01 -3.23e-02 9.18e-01
REACTOME GLYCOGEN SYNTHESIS 13 5.23e-01 1.02e-01 9.18e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 5.24e-01 -9.21e-02 9.18e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 5.24e-01 -4.41e-02 9.18e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 5.24e-01 -7.67e-02 9.18e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 5.25e-01 8.43e-02 9.18e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 5.25e-01 9.48e-02 9.18e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 5.25e-01 -3.53e-02 9.18e-01
REACTOME METABOLISM OF POLYAMINES 56 5.27e-01 -4.89e-02 9.18e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 5.27e-01 -1.16e-01 9.18e-01
REACTOME SYNDECAN INTERACTIONS 26 5.27e-01 7.17e-02 9.18e-01
REACTOME DISEASES OF BASE EXCISION REPAIR 5 5.27e-01 -1.63e-01 9.18e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 5.28e-01 7.44e-02 9.20e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 5.30e-01 -5.29e-02 9.22e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 5.31e-01 1.37e-01 9.22e-01
REACTOME NEUROTRANSMITTER CLEARANCE 9 5.31e-01 1.20e-01 9.22e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 5.32e-01 7.89e-02 9.22e-01
REACTOME INFECTIOUS DISEASE 910 5.33e-01 -1.22e-02 9.22e-01
REACTOME PI3K AKT ACTIVATION 9 5.33e-01 -1.20e-01 9.22e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 5.34e-01 -1.08e-01 9.22e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 5.35e-01 5.60e-02 9.23e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 5.36e-01 1.08e-01 9.23e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 5.36e-01 -1.19e-01 9.23e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 5.37e-01 -1.08e-01 9.23e-01
REACTOME CREB PHOSPHORYLATION 6 5.38e-01 -1.45e-01 9.23e-01
REACTOME SARS COV 2 INFECTION 281 5.38e-01 2.13e-02 9.23e-01
REACTOME TRANSPORT OF ORGANIC ANIONS 10 5.40e-01 1.12e-01 9.23e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 5.40e-01 1.44e-01 9.23e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 5.41e-01 -1.18e-01 9.23e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 5.44e-01 -1.24e-01 9.23e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 5.45e-01 -4.52e-02 9.23e-01
REACTOME GLUCONEOGENESIS 33 5.46e-01 -6.07e-02 9.23e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 5.46e-01 -1.16e-01 9.23e-01
REACTOME SIGNALING BY ROBO RECEPTORS 206 5.47e-01 -2.43e-02 9.23e-01
REACTOME HISTIDINE CATABOLISM 8 5.47e-01 -1.23e-01 9.23e-01
REACTOME SYNTHESIS OF KETONE BODIES 8 5.49e-01 -1.22e-01 9.23e-01
REACTOME PHASE 0 RAPID DEPOLARISATION 31 5.49e-01 6.21e-02 9.23e-01
REACTOME RHOV GTPASE CYCLE 36 5.49e-01 5.77e-02 9.23e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 5.50e-01 -1.31e-01 9.23e-01
REACTOME SELENOAMINO ACID METABOLISM 108 5.50e-01 3.33e-02 9.23e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 5.51e-01 1.30e-01 9.23e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 5.52e-01 9.19e-02 9.23e-01
REACTOME MTORC1 MEDIATED SIGNALLING 23 5.53e-01 -7.15e-02 9.23e-01
REACTOME MAPK3 ERK1 ACTIVATION 10 5.55e-01 -1.08e-01 9.23e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 5.57e-01 7.58e-02 9.23e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 5.58e-01 8.74e-02 9.23e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 5.58e-01 3.63e-02 9.23e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 5.59e-01 -7.19e-02 9.23e-01
REACTOME HDACS DEACETYLATE HISTONES 85 5.60e-01 3.66e-02 9.23e-01
REACTOME TP53 REGULATES METABOLIC GENES 81 5.61e-01 -3.74e-02 9.23e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 5.61e-01 8.39e-02 9.23e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 5.62e-01 -1.50e-01 9.23e-01
REACTOME KILLING MECHANISMS 11 5.62e-01 -1.01e-01 9.23e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 5.62e-01 -6.01e-02 9.23e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 5.63e-01 -7.67e-02 9.23e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 5.65e-01 5.78e-02 9.23e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 5.66e-01 -1.25e-01 9.23e-01
REACTOME NADE MODULATES DEATH SIGNALLING 5 5.67e-01 1.48e-01 9.23e-01
REACTOME HDMS DEMETHYLATE HISTONES 40 5.67e-01 5.24e-02 9.23e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 5.67e-01 -5.37e-02 9.23e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 5.68e-01 3.04e-02 9.23e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 5.69e-01 7.35e-02 9.23e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 5.70e-01 -3.54e-02 9.23e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 5.71e-01 6.83e-02 9.23e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 5.71e-01 -5.53e-02 9.23e-01
REACTOME INTERLEUKIN 35 SIGNALLING 12 5.72e-01 -9.43e-02 9.23e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 5.72e-01 1.15e-01 9.23e-01
REACTOME STAT5 ACTIVATION 7 5.72e-01 1.23e-01 9.23e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 5.74e-01 -7.26e-02 9.23e-01
REACTOME METAL ION SLC TRANSPORTERS 23 5.75e-01 6.76e-02 9.23e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 5.75e-01 7.85e-02 9.23e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 5.76e-01 -1.22e-01 9.23e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 5.76e-01 6.74e-02 9.23e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 5.76e-01 -7.22e-02 9.23e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 5.76e-01 -3.89e-02 9.23e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 5.76e-01 -2.55e-02 9.23e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 5.77e-01 -1.07e-01 9.23e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 5.77e-01 6.32e-02 9.23e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 5.77e-01 -1.22e-01 9.23e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 5.77e-01 -6.09e-02 9.23e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 5.77e-01 1.14e-01 9.23e-01
REACTOME CALNEXIN CALRETICULIN CYCLE 26 5.78e-01 -6.31e-02 9.23e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 5.78e-01 -7.79e-02 9.23e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 5.79e-01 -8.57e-02 9.23e-01
REACTOME HS GAG DEGRADATION 19 5.80e-01 7.34e-02 9.23e-01
REACTOME CDC42 GTPASE CYCLE 144 5.80e-01 -2.67e-02 9.23e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 5.80e-01 7.33e-02 9.23e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 5.83e-01 9.16e-02 9.23e-01
REACTOME EXTENSION OF TELOMERES 49 5.83e-01 -4.53e-02 9.23e-01
REACTOME ACYL CHAIN REMODELLING OF PE 29 5.84e-01 -5.88e-02 9.23e-01
REACTOME RIBAVIRIN ADME 11 5.84e-01 9.54e-02 9.23e-01
REACTOME AMINO ACIDS REGULATE MTORC1 53 5.84e-01 -4.35e-02 9.23e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 5.84e-01 -8.76e-02 9.23e-01
REACTOME ACTIVATION OF C3 AND C5 6 5.84e-01 -1.29e-01 9.23e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 5.84e-01 -5.87e-02 9.23e-01
REACTOME SOS MEDIATED SIGNALLING 7 5.86e-01 1.19e-01 9.23e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 5.87e-01 -1.05e-01 9.23e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 5.87e-01 -5.73e-02 9.23e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 5.88e-01 -2.29e-02 9.23e-01
REACTOME P2Y RECEPTORS 9 5.88e-01 -1.04e-01 9.23e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 5.89e-01 -5.90e-02 9.23e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 5.89e-01 -5.20e-02 9.23e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 5.90e-01 1.39e-01 9.23e-01
REACTOME DISEASES OF IMMUNE SYSTEM 29 5.90e-01 -5.78e-02 9.23e-01
REACTOME NEDDYLATION 235 5.90e-01 -2.04e-02 9.23e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 5.90e-01 -7.77e-02 9.23e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 5.91e-01 5.77e-02 9.23e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 5.91e-01 -1.10e-01 9.23e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 5.91e-01 -5.76e-02 9.23e-01
REACTOME IRS ACTIVATION 5 5.92e-01 1.39e-01 9.23e-01
REACTOME SIGNALING BY MST1 5 5.92e-01 1.38e-01 9.23e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 5.96e-01 1.08e-01 9.23e-01
REACTOME ENDOGENOUS STEROLS 26 5.97e-01 5.99e-02 9.23e-01
REACTOME SIGNALING BY MAPK MUTANTS 6 5.98e-01 -1.24e-01 9.23e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 6.00e-01 -3.44e-02 9.23e-01
REACTOME SIGNALING BY SCF KIT 42 6.01e-01 4.67e-02 9.23e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 6.01e-01 -3.52e-02 9.23e-01
REACTOME CARDIAC CONDUCTION 125 6.01e-01 -2.71e-02 9.23e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 6.04e-01 9.46e-02 9.23e-01
REACTOME SLC TRANSPORTER DISORDERS 94 6.06e-01 3.08e-02 9.23e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 6.06e-01 2.54e-02 9.23e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 6.07e-01 3.91e-02 9.23e-01
REACTOME SIGNALING BY KIT IN DISEASE 20 6.07e-01 6.65e-02 9.23e-01
REACTOME DEVELOPMENTAL BIOLOGY 1115 6.07e-01 -9.13e-03 9.23e-01
REACTOME STABILIZATION OF P53 56 6.07e-01 -3.97e-02 9.23e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 6.08e-01 -3.63e-02 9.23e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 6.08e-01 -3.73e-02 9.23e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 6.08e-01 -7.64e-02 9.23e-01
REACTOME SYNTHESIS OF GDP MANNOSE 5 6.09e-01 -1.32e-01 9.23e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 6.09e-01 -1.32e-01 9.23e-01
REACTOME LDL CLEARANCE 19 6.09e-01 -6.78e-02 9.23e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 6.10e-01 -8.89e-02 9.23e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 6.10e-01 -4.01e-02 9.23e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 6.12e-01 -1.04e-01 9.23e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 6.14e-01 -3.56e-02 9.23e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 6.14e-01 -7.29e-02 9.23e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 6.15e-01 2.42e-02 9.23e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 6.15e-01 -3.69e-02 9.23e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 6.15e-01 8.38e-02 9.23e-01
REACTOME SIGNALING BY RETINOIC ACID 41 6.16e-01 -4.53e-02 9.23e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 6.16e-01 1.29e-01 9.23e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 6.17e-01 9.13e-02 9.23e-01
REACTOME FORMATION OF APOPTOSOME 10 6.17e-01 -9.13e-02 9.23e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 6.19e-01 8.30e-02 9.23e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 6.19e-01 5.75e-02 9.23e-01
REACTOME PI 3K CASCADE FGFR2 22 6.19e-01 6.12e-02 9.23e-01
REACTOME RHO GTPASES ACTIVATE ROCKS 19 6.19e-01 6.59e-02 9.23e-01
REACTOME PROPIONYL COA CATABOLISM 5 6.19e-01 -1.28e-01 9.23e-01
REACTOME HSF1 ACTIVATION 29 6.19e-01 -5.33e-02 9.23e-01
REACTOME IRS MEDIATED SIGNALLING 47 6.20e-01 4.19e-02 9.23e-01
REACTOME DNA REPAIR 321 6.20e-01 -1.61e-02 9.23e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 6.22e-01 -1.51e-02 9.23e-01
REACTOME RAC2 GTPASE CYCLE 81 6.22e-01 -3.17e-02 9.23e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 6.23e-01 6.06e-02 9.23e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 6.24e-01 -4.79e-02 9.23e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 6.25e-01 -1.07e-01 9.23e-01
REACTOME PHENYLALANINE METABOLISM 6 6.25e-01 1.15e-01 9.23e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 6.25e-01 7.55e-02 9.23e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 6.26e-01 -3.35e-02 9.23e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 6.26e-01 4.15e-02 9.23e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 6.26e-01 1.15e-01 9.23e-01
REACTOME CD22 MEDIATED BCR REGULATION 5 6.26e-01 -1.26e-01 9.23e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 6.27e-01 -8.88e-02 9.23e-01
REACTOME GAB1 SIGNALOSOME 17 6.27e-01 -6.81e-02 9.23e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 6.28e-01 -6.43e-02 9.23e-01
REACTOME SIGNALING BY ERBB2 IN CANCER 26 6.29e-01 5.48e-02 9.23e-01
REACTOME MITOCHONDRIAL TRANSLATION 93 6.29e-01 2.90e-02 9.23e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 6.29e-01 -1.69e-02 9.23e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 6.29e-01 -3.52e-02 9.23e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 6.29e-01 1.25e-01 9.23e-01
REACTOME METALLOTHIONEINS BIND METALS 11 6.30e-01 -8.38e-02 9.23e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 6.30e-01 5.67e-02 9.23e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 6.31e-01 -1.05e-01 9.23e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 6.32e-01 5.77e-02 9.23e-01
REACTOME REGULATION OF RAS BY GAPS 66 6.32e-01 -3.41e-02 9.23e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 6.32e-01 -6.04e-02 9.23e-01
REACTOME INFLUENZA INFECTION 149 6.32e-01 2.27e-02 9.23e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 6.32e-01 4.75e-02 9.23e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 6.33e-01 6.70e-02 9.23e-01
REACTOME ALPHA OXIDATION OF PHYTANATE 6 6.33e-01 1.13e-01 9.23e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 6.33e-01 -6.02e-02 9.23e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 6.34e-01 3.82e-02 9.23e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 6.36e-01 5.18e-02 9.23e-01
REACTOME TIGHT JUNCTION INTERACTIONS 29 6.36e-01 -5.08e-02 9.23e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 6.36e-01 -8.24e-02 9.23e-01
REACTOME FORMATION OF PARAXIAL MESODERM 22 6.37e-01 -5.81e-02 9.23e-01
REACTOME ESR MEDIATED SIGNALING 210 6.37e-01 -1.89e-02 9.23e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 6.37e-01 -3.71e-02 9.23e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 6.38e-01 -1.22e-01 9.23e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 6.38e-01 3.30e-02 9.23e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 6.39e-01 3.56e-02 9.23e-01
REACTOME HATS ACETYLATE HISTONES 129 6.39e-01 2.39e-02 9.23e-01
REACTOME MUCOPOLYSACCHARIDOSES 10 6.40e-01 -8.55e-02 9.23e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 6.40e-01 -5.30e-02 9.23e-01
REACTOME NICOTINATE METABOLISM 31 6.40e-01 -4.86e-02 9.23e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 6.40e-01 -3.08e-02 9.23e-01
REACTOME INFLAMMASOMES 21 6.42e-01 -5.85e-02 9.23e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 6.42e-01 8.94e-02 9.23e-01
REACTOME RHOF GTPASE CYCLE 40 6.44e-01 -4.22e-02 9.23e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 6.44e-01 -3.04e-02 9.23e-01
REACTOME MITOTIC PROMETAPHASE 194 6.45e-01 1.92e-02 9.23e-01
REACTOME APOPTOSIS 173 6.45e-01 -2.03e-02 9.23e-01
REACTOME SENSORY PROCESSING OF SOUND 72 6.46e-01 3.14e-02 9.23e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 6.46e-01 7.36e-02 9.23e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 6.46e-01 7.09e-02 9.23e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 6.47e-01 8.82e-02 9.23e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 6.47e-01 4.29e-02 9.23e-01
REACTOME CALCINEURIN ACTIVATES NFAT 9 6.47e-01 -8.81e-02 9.23e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 6.47e-01 6.61e-02 9.23e-01
REACTOME INTERLEUKIN 18 SIGNALING 8 6.48e-01 -9.33e-02 9.23e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 6.48e-01 5.39e-02 9.23e-01
REACTOME P38MAPK EVENTS 13 6.49e-01 7.29e-02 9.23e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 6.50e-01 7.57e-02 9.23e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 6.50e-01 -6.18e-02 9.23e-01
REACTOME ION HOMEOSTASIS 52 6.50e-01 -3.64e-02 9.23e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 6.50e-01 -3.09e-02 9.23e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 6.51e-01 -1.17e-01 9.23e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 6.51e-01 9.23e-02 9.23e-01
REACTOME ALPHA DEFENSINS 6 6.51e-01 -1.06e-01 9.23e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 6.52e-01 -7.53e-02 9.23e-01
REACTOME MET ACTIVATES RAS SIGNALING 11 6.52e-01 7.86e-02 9.23e-01
REACTOME SUMOYLATION 179 6.52e-01 1.95e-02 9.23e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 6.52e-01 -6.13e-02 9.23e-01
REACTOME RUNX3 REGULATES WNT SIGNALING 8 6.52e-01 9.20e-02 9.23e-01
REACTOME P75NTR SIGNALS VIA NF KB 15 6.53e-01 -6.71e-02 9.23e-01
REACTOME CARNITINE METABOLISM 13 6.53e-01 -7.20e-02 9.23e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 6.54e-01 7.48e-02 9.23e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 6.54e-01 -2.62e-02 9.23e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 6.54e-01 8.63e-02 9.23e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 6.55e-01 1.05e-01 9.23e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 6.55e-01 -1.51e-02 9.23e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 6.56e-01 3.02e-02 9.23e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 6.56e-01 3.79e-02 9.23e-01
REACTOME REGULATION OF PTEN LOCALIZATION 8 6.56e-01 -9.08e-02 9.23e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 6.57e-01 4.77e-02 9.23e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 6.57e-01 -1.05e-01 9.23e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 6.57e-01 -8.54e-02 9.23e-01
REACTOME CHL1 INTERACTIONS 9 6.57e-01 -8.54e-02 9.23e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 6.58e-01 -8.53e-02 9.23e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 6.58e-01 -4.00e-02 9.23e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 6.60e-01 -2.51e-02 9.24e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 6.60e-01 6.56e-02 9.24e-01
REACTOME SMOOTH MUSCLE CONTRACTION 43 6.60e-01 -3.88e-02 9.24e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 6.60e-01 -1.13e-01 9.24e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 6.62e-01 1.13e-01 9.24e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 6.62e-01 -1.13e-01 9.24e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 6.62e-01 6.52e-02 9.24e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 6.63e-01 -5.13e-02 9.25e-01
REACTOME CELL CYCLE 666 6.64e-01 9.87e-03 9.25e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 6.65e-01 6.69e-02 9.25e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 6.65e-01 -4.29e-02 9.25e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 6.66e-01 -1.54e-02 9.25e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 6.67e-01 5.19e-02 9.25e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 6.67e-01 -1.11e-01 9.26e-01
REACTOME PROSTANOID LIGAND RECEPTORS 9 6.69e-01 8.23e-02 9.27e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 6.71e-01 5.24e-02 9.28e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 6.72e-01 5.92e-02 9.29e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 6.73e-01 -8.63e-02 9.29e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 6.73e-01 4.45e-02 9.29e-01
REACTOME THE NLRP3 INFLAMMASOME 16 6.73e-01 -6.09e-02 9.29e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 6.74e-01 -5.58e-02 9.29e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 6.75e-01 4.29e-02 9.29e-01
REACTOME CHYLOMICRON ASSEMBLY 10 6.75e-01 -7.65e-02 9.29e-01
REACTOME INTERLEUKIN 23 SIGNALING 9 6.76e-01 -8.04e-02 9.30e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 6.77e-01 7.25e-02 9.30e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 6.78e-01 -7.99e-02 9.30e-01
REACTOME ACTIVATION OF RAC1 12 6.78e-01 6.92e-02 9.30e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 6.80e-01 -4.43e-02 9.30e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 6.80e-01 4.21e-02 9.30e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 6.80e-01 -5.19e-02 9.30e-01
REACTOME SEMAPHORIN INTERACTIONS 61 6.81e-01 -3.04e-02 9.30e-01
REACTOME SIGNALING BY FGFR3 39 6.81e-01 -3.80e-02 9.30e-01
REACTOME POLYMERASE SWITCHING 13 6.81e-01 6.58e-02 9.30e-01
REACTOME SIGNALING BY PDGFR IN DISEASE 20 6.82e-01 -5.29e-02 9.30e-01
REACTOME HDL ASSEMBLY 8 6.83e-01 8.34e-02 9.30e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 6.84e-01 -3.68e-02 9.31e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 6.84e-01 -2.61e-02 9.31e-01
REACTOME HIV LIFE CYCLE 145 6.87e-01 1.94e-02 9.34e-01
REACTOME METALLOPROTEASE DUBS 36 6.88e-01 -3.87e-02 9.34e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 6.90e-01 5.28e-02 9.34e-01
REACTOME LAGGING STRAND SYNTHESIS 19 6.90e-01 5.28e-02 9.34e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 6.91e-01 -4.19e-02 9.34e-01
REACTOME ADRENOCEPTORS 9 6.91e-01 -7.64e-02 9.34e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 6.91e-01 -4.78e-02 9.34e-01
REACTOME STIMULI SENSING CHANNELS 100 6.92e-01 2.29e-02 9.34e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 6.93e-01 -5.37e-02 9.34e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 6.93e-01 -9.30e-02 9.34e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 6.94e-01 -7.58e-02 9.34e-01
REACTOME SPERM MOTILITY AND TAXES 9 6.94e-01 7.58e-02 9.34e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 6.94e-01 -4.21e-02 9.34e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 6.96e-01 3.11e-02 9.34e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 6.96e-01 -3.26e-02 9.34e-01
REACTOME SIGNALING BY FGFR IN DISEASE 62 6.97e-01 2.86e-02 9.34e-01
REACTOME DIGESTION AND ABSORPTION 22 6.97e-01 4.80e-02 9.34e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 6.97e-01 2.93e-02 9.34e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 6.99e-01 -9.11e-02 9.37e-01
REACTOME HIV INFECTION 223 7.01e-01 -1.49e-02 9.38e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 7.02e-01 -4.51e-02 9.38e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 7.02e-01 2.29e-02 9.38e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 7.02e-01 5.52e-02 9.38e-01
REACTOME SIGNALING BY NOTCH 234 7.04e-01 -1.44e-02 9.39e-01
REACTOME DEADENYLATION OF MRNA 25 7.06e-01 4.36e-02 9.40e-01
REACTOME SYNTHESIS OF PI 5 7.06e-01 -9.74e-02 9.40e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 7.08e-01 -4.17e-02 9.42e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 7.08e-01 6.00e-02 9.42e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 7.09e-01 4.82e-02 9.42e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 7.11e-01 1.81e-02 9.44e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 7.12e-01 -8.70e-02 9.45e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 7.14e-01 7.05e-02 9.47e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 7.18e-01 9.34e-02 9.50e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 7.20e-01 3.45e-02 9.52e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 7.22e-01 -4.49e-02 9.52e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 7.23e-01 -6.47e-02 9.52e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 7.23e-01 -8.36e-02 9.52e-01
REACTOME PROGRAMMED CELL DEATH 204 7.23e-01 -1.44e-02 9.52e-01
REACTOME FRUCTOSE METABOLISM 7 7.23e-01 -7.73e-02 9.52e-01
REACTOME SHC MEDIATED CASCADE FGFR1 21 7.24e-01 4.46e-02 9.52e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 7.24e-01 7.71e-02 9.52e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 7.26e-01 -6.74e-02 9.53e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 7.26e-01 7.15e-02 9.53e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 7.27e-01 -2.21e-02 9.53e-01
REACTOME DNA STRAND ELONGATION 31 7.28e-01 -3.61e-02 9.53e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 7.28e-01 4.38e-02 9.53e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 7.28e-01 -1.85e-02 9.53e-01
REACTOME FGFR2 ALTERNATIVE SPLICING 27 7.28e-01 3.86e-02 9.53e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 7.29e-01 2.76e-02 9.53e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 7.30e-01 -3.27e-02 9.54e-01
REACTOME CHROMOSOME MAINTENANCE 130 7.33e-01 1.73e-02 9.54e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 7.34e-01 8.77e-02 9.54e-01
REACTOME PROTEIN UBIQUITINATION 76 7.34e-01 2.25e-02 9.54e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 7.35e-01 -7.98e-02 9.54e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 7.36e-01 1.77e-02 9.54e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 7.36e-01 -2.68e-02 9.54e-01
REACTOME PI 3K CASCADE FGFR1 21 7.36e-01 4.24e-02 9.54e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 7.37e-01 6.14e-02 9.54e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 7.37e-01 2.21e-02 9.54e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 7.37e-01 3.06e-02 9.54e-01
REACTOME INSULIN PROCESSING 24 7.38e-01 3.95e-02 9.54e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 7.38e-01 4.22e-02 9.54e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 7.38e-01 3.71e-02 9.54e-01
REACTOME RHO GTPASE CYCLE 423 7.39e-01 -9.43e-03 9.54e-01
REACTOME TRANSPORT OF FATTY ACIDS 8 7.40e-01 -6.76e-02 9.54e-01
REACTOME SIGNALING BY FGFR1 49 7.41e-01 -2.73e-02 9.54e-01
REACTOME COHESIN LOADING ONTO CHROMATIN 8 7.41e-01 6.75e-02 9.54e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 7.42e-01 -2.57e-02 9.54e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 7.42e-01 -4.25e-02 9.54e-01
REACTOME ERBB2 REGULATES CELL MOTILITY 15 7.42e-01 -4.91e-02 9.54e-01
REACTOME UREA CYCLE 9 7.43e-01 6.31e-02 9.54e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 7.44e-01 -5.96e-02 9.54e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 7.45e-01 3.56e-02 9.54e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 7.45e-01 -6.27e-02 9.54e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 7.46e-01 3.13e-02 9.54e-01
REACTOME KINESINS 59 7.46e-01 -2.44e-02 9.54e-01
REACTOME G PROTEIN ACTIVATION 24 7.46e-01 -3.81e-02 9.54e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 7.47e-01 -2.28e-02 9.54e-01
REACTOME KERATAN SULFATE DEGRADATION 13 7.47e-01 5.17e-02 9.54e-01
REACTOME RHOD GTPASE CYCLE 49 7.48e-01 2.65e-02 9.55e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 7.49e-01 -4.94e-02 9.55e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 7.50e-01 2.14e-02 9.55e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 7.53e-01 6.06e-02 9.56e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 7.53e-01 -4.86e-02 9.56e-01
REACTOME 2 LTR CIRCLE FORMATION 7 7.53e-01 6.86e-02 9.56e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 7.53e-01 -1.43e-02 9.56e-01
REACTOME RHOBTB2 GTPASE CYCLE 22 7.54e-01 -3.87e-02 9.56e-01
REACTOME SIGNALING BY NTRK3 TRKC 17 7.54e-01 4.39e-02 9.56e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 7.57e-01 6.76e-02 9.58e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 7.58e-01 -4.08e-02 9.58e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 7.58e-01 6.28e-02 9.58e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 7.58e-01 -2.03e-02 9.58e-01
REACTOME TCR SIGNALING 113 7.59e-01 -1.67e-02 9.58e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 7.60e-01 -6.68e-02 9.58e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 7.61e-01 3.11e-02 9.58e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 7.62e-01 -2.88e-02 9.58e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 7.62e-01 4.85e-02 9.58e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 7.63e-01 5.52e-02 9.58e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 7.64e-01 2.17e-02 9.58e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 7.64e-01 -3.07e-02 9.58e-01
REACTOME DECTIN 2 FAMILY 26 7.64e-01 -3.40e-02 9.58e-01
REACTOME ZINC TRANSPORTERS 15 7.64e-01 -4.47e-02 9.58e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 7.65e-01 7.04e-02 9.58e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 7.65e-01 -3.15e-02 9.58e-01
REACTOME MET RECEPTOR ACTIVATION 6 7.66e-01 7.02e-02 9.58e-01
REACTOME FERTILIZATION 26 7.67e-01 -3.35e-02 9.58e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 7.68e-01 4.56e-02 9.58e-01
REACTOME NEUREXINS AND NEUROLIGINS 51 7.68e-01 -2.39e-02 9.58e-01
REACTOME PD 1 SIGNALING 21 7.69e-01 -3.71e-02 9.58e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 7.69e-01 4.54e-02 9.58e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 7.69e-01 -4.89e-02 9.58e-01
REACTOME SIGNALING BY HIPPO 19 7.70e-01 3.87e-02 9.58e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 7.70e-01 -4.09e-02 9.58e-01
REACTOME PROTEIN FOLDING 96 7.71e-01 -1.72e-02 9.58e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 7.72e-01 -3.16e-02 9.59e-01
REACTOME MISMATCH REPAIR 15 7.77e-01 -4.21e-02 9.62e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 7.78e-01 2.24e-02 9.62e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 7.78e-01 -3.48e-02 9.62e-01
REACTOME IKBA VARIANT LEADS TO EDA ID 6 7.79e-01 -6.62e-02 9.62e-01
REACTOME SIGNALING BY FGFR 85 7.79e-01 1.76e-02 9.62e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 7.80e-01 6.11e-02 9.62e-01
REACTOME SIGNALING BY ERBB2 50 7.80e-01 -2.28e-02 9.62e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 7.80e-01 -4.02e-02 9.62e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 7.81e-01 -2.93e-02 9.62e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 7.81e-01 6.55e-02 9.62e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 7.81e-01 -2.34e-02 9.62e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 7.82e-01 7.13e-02 9.63e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 7.83e-01 -4.80e-02 9.63e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 7.83e-01 -3.24e-02 9.63e-01
REACTOME TRNA PROCESSING 105 7.85e-01 1.54e-02 9.64e-01
REACTOME GAP JUNCTION ASSEMBLY 36 7.87e-01 -2.61e-02 9.65e-01
REACTOME PROTEIN LOCALIZATION 153 7.88e-01 -1.26e-02 9.65e-01
REACTOME INTERLEUKIN 21 SIGNALING 9 7.88e-01 -5.18e-02 9.65e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 7.89e-01 -4.67e-02 9.65e-01
REACTOME HDL CLEARANCE 5 7.89e-01 6.91e-02 9.65e-01
REACTOME AUTOPHAGY 144 7.89e-01 -1.29e-02 9.65e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 7.91e-01 5.41e-02 9.66e-01
REACTOME HEME BIOSYNTHESIS 13 7.92e-01 -4.23e-02 9.66e-01
REACTOME RA BIOSYNTHESIS PATHWAY 22 7.92e-01 3.25e-02 9.66e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 7.93e-01 3.39e-02 9.66e-01
REACTOME TYROSINE CATABOLISM 5 7.94e-01 -6.75e-02 9.66e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 7.95e-01 1.43e-02 9.66e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 7.95e-01 -3.75e-02 9.66e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 7.95e-01 -3.44e-02 9.66e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 7.96e-01 -2.78e-02 9.67e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 7.97e-01 -2.26e-02 9.67e-01
REACTOME REGULATION OF BACH1 ACTIVITY 11 7.98e-01 4.47e-02 9.67e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 7.98e-01 -2.85e-02 9.67e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 7.99e-01 6.01e-02 9.67e-01
REACTOME DISINHIBITION OF SNARE FORMATION 5 8.03e-01 6.43e-02 9.72e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 8.04e-01 3.97e-02 9.72e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 8.07e-01 2.83e-02 9.74e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 8.07e-01 -3.42e-02 9.74e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 8.07e-01 -4.45e-02 9.74e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 8.09e-01 -5.71e-02 9.74e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 8.09e-01 -3.61e-02 9.74e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 8.11e-01 4.16e-02 9.76e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 8.12e-01 3.43e-02 9.76e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 8.13e-01 3.42e-02 9.76e-01
REACTOME FANCONI ANEMIA PATHWAY 35 8.14e-01 2.30e-02 9.76e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 8.14e-01 2.37e-02 9.76e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 8.15e-01 -5.12e-02 9.76e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 8.15e-01 3.62e-02 9.76e-01
REACTOME RHOQ GTPASE CYCLE 57 8.15e-01 -1.79e-02 9.76e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 8.17e-01 1.87e-02 9.76e-01
REACTOME SYNTHESIS OF PC 27 8.17e-01 2.57e-02 9.76e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 8.18e-01 -2.24e-02 9.76e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 8.19e-01 -5.40e-02 9.76e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 8.19e-01 1.73e-02 9.76e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 8.19e-01 -2.37e-02 9.76e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 8.19e-01 3.30e-02 9.76e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 8.24e-01 -4.55e-02 9.79e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 8.24e-01 -3.55e-02 9.79e-01
REACTOME CHOLESTEROL BIOSYNTHESIS 25 8.24e-01 -2.56e-02 9.79e-01
REACTOME PEROXISOMAL PROTEIN IMPORT 62 8.25e-01 -1.63e-02 9.79e-01
REACTOME TIE2 SIGNALING 18 8.26e-01 3.00e-02 9.79e-01
REACTOME NRCAM INTERACTIONS 6 8.26e-01 5.18e-02 9.79e-01
REACTOME SULFIDE OXIDATION TO SULFATE 6 8.26e-01 -5.17e-02 9.79e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 8.27e-01 2.63e-02 9.79e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 8.27e-01 2.26e-02 9.79e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 8.28e-01 -4.44e-02 9.79e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 8.31e-01 -5.52e-02 9.80e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 8.31e-01 -1.14e-02 9.80e-01
REACTOME RHOU GTPASE CYCLE 37 8.32e-01 -2.01e-02 9.80e-01
REACTOME FCGR ACTIVATION 11 8.34e-01 -3.66e-02 9.80e-01
REACTOME CELLULAR SENESCENCE 189 8.35e-01 8.79e-03 9.80e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 8.35e-01 -2.62e-02 9.80e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 8.35e-01 3.21e-02 9.80e-01
REACTOME CILIUM ASSEMBLY 190 8.36e-01 8.73e-03 9.80e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 8.36e-01 2.15e-02 9.80e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 8.37e-01 -2.81e-02 9.80e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 8.37e-01 -2.38e-02 9.80e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 8.37e-01 -1.84e-02 9.80e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 8.38e-01 -3.57e-02 9.80e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 8.38e-01 -3.28e-02 9.80e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 8.39e-01 -3.92e-02 9.80e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 8.39e-01 -5.24e-02 9.80e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 8.40e-01 -5.22e-02 9.80e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 8.40e-01 2.48e-02 9.80e-01
REACTOME SELECTIVE AUTOPHAGY 79 8.41e-01 -1.30e-02 9.80e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 8.42e-01 -1.28e-02 9.80e-01
REACTOME NONSENSE MEDIATED DECAY NMD 107 8.43e-01 1.11e-02 9.80e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 8.43e-01 -3.82e-02 9.80e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 8.43e-01 -1.41e-02 9.80e-01
REACTOME PARACETAMOL ADME 26 8.43e-01 -2.24e-02 9.80e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 8.43e-01 3.61e-02 9.80e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 8.44e-01 2.15e-02 9.80e-01
REACTOME GLUTATHIONE CONJUGATION 33 8.47e-01 1.94e-02 9.83e-01
REACTOME INTERLEUKIN 1 PROCESSING 9 8.48e-01 -3.70e-02 9.83e-01
REACTOME ASSEMBLY OF THE HIV VIRION 16 8.49e-01 2.76e-02 9.83e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 8.51e-01 3.14e-02 9.83e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 8.51e-01 -3.14e-02 9.83e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 8.52e-01 -3.25e-02 9.83e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 8.52e-01 4.81e-02 9.83e-01
REACTOME HIV TRANSCRIPTION INITIATION 43 8.53e-01 1.64e-02 9.83e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 8.53e-01 1.83e-02 9.83e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 8.53e-01 3.22e-02 9.83e-01
REACTOME RUNX3 REGULATES P14 ARF 10 8.55e-01 -3.33e-02 9.83e-01
REACTOME RAC3 GTPASE CYCLE 85 8.56e-01 1.14e-02 9.83e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 8.56e-01 1.68e-02 9.83e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 8.56e-01 3.31e-02 9.83e-01
REACTOME INTERLEUKIN 1 SIGNALING 110 8.57e-01 -9.98e-03 9.83e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 8.57e-01 -1.46e-02 9.83e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 8.58e-01 -1.66e-02 9.83e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 8.58e-01 -1.42e-02 9.83e-01
REACTOME MITOPHAGY 28 8.59e-01 -1.94e-02 9.83e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 8.61e-01 -4.53e-02 9.83e-01
REACTOME ENOS ACTIVATION 11 8.62e-01 3.03e-02 9.83e-01
REACTOME DAP12 INTERACTIONS 37 8.62e-01 -1.65e-02 9.83e-01
REACTOME ACTIVATION OF RAS IN B CELLS 5 8.63e-01 4.47e-02 9.83e-01
REACTOME GLYCOGEN METABOLISM 22 8.63e-01 2.13e-02 9.83e-01
REACTOME SIGNALING BY FGFR2 72 8.63e-01 -1.17e-02 9.83e-01
REACTOME INTRA GOLGI TRAFFIC 43 8.64e-01 -1.51e-02 9.83e-01
REACTOME NEPHRIN FAMILY INTERACTIONS 22 8.64e-01 2.11e-02 9.83e-01
REACTOME SYNTHESIS OF DNA 119 8.65e-01 -9.00e-03 9.83e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 8.67e-01 1.12e-02 9.83e-01
REACTOME SARS COV INFECTIONS 392 8.67e-01 -4.91e-03 9.83e-01
REACTOME VITAMINS 6 8.68e-01 3.91e-02 9.83e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 8.68e-01 3.19e-02 9.83e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 8.70e-01 3.57e-02 9.83e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 8.70e-01 -2.43e-02 9.83e-01
REACTOME NUCLEOTIDE SALVAGE 21 8.71e-01 2.05e-02 9.83e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 8.71e-01 2.09e-02 9.83e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 8.72e-01 3.52e-02 9.83e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 8.72e-01 -2.81e-02 9.83e-01
REACTOME S PHASE 159 8.72e-01 7.39e-03 9.83e-01
REACTOME PYROPTOSIS 27 8.73e-01 -1.77e-02 9.83e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 8.74e-01 1.92e-02 9.83e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 8.74e-01 -1.83e-02 9.83e-01
REACTOME DNA DAMAGE REVERSAL 8 8.74e-01 3.23e-02 9.83e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 8.75e-01 1.42e-02 9.83e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 8.75e-01 8.37e-03 9.83e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 8.76e-01 1.24e-02 9.83e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 8.76e-01 1.65e-02 9.83e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 8.76e-01 4.03e-02 9.83e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 8.77e-01 -1.83e-02 9.83e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 8.77e-01 -1.64e-02 9.83e-01
REACTOME EPHRIN SIGNALING 17 8.78e-01 2.15e-02 9.84e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 8.78e-01 -2.46e-02 9.84e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 8.81e-01 -6.64e-03 9.86e-01
REACTOME CHYLOMICRON CLEARANCE 5 8.82e-01 -3.84e-02 9.86e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 8.82e-01 8.55e-03 9.86e-01
REACTOME RHOJ GTPASE CYCLE 51 8.82e-01 -1.20e-02 9.86e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 8.84e-01 -3.77e-02 9.86e-01
REACTOME CRISTAE FORMATION 27 8.85e-01 -1.61e-02 9.86e-01
REACTOME ANCHORING FIBRIL FORMATION 13 8.85e-01 2.31e-02 9.86e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 8.86e-01 1.35e-02 9.86e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 8.86e-01 -1.57e-02 9.86e-01
REACTOME INTRAFLAGELLAR TRANSPORT 50 8.87e-01 1.16e-02 9.86e-01
REACTOME SIGNALLING TO RAS 20 8.87e-01 1.84e-02 9.86e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 8.88e-01 -3.07e-02 9.86e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 8.89e-01 -1.81e-02 9.86e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 8.90e-01 -1.93e-02 9.88e-01
REACTOME TRIGLYCERIDE CATABOLISM 23 8.92e-01 1.64e-02 9.88e-01
REACTOME SIGNAL ATTENUATION 10 8.94e-01 -2.44e-02 9.88e-01
REACTOME AGGREPHAGY 42 8.94e-01 1.19e-02 9.88e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 8.94e-01 1.57e-02 9.88e-01
REACTOME ROBO RECEPTORS BIND AKAP5 9 8.94e-01 -2.55e-02 9.88e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 8.95e-01 1.75e-02 9.88e-01
REACTOME ACTIVATION OF TRKA RECEPTORS 6 8.95e-01 -3.10e-02 9.88e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 8.97e-01 -1.42e-02 9.88e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 8.98e-01 1.92e-02 9.88e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 8.98e-01 2.62e-02 9.88e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 8.98e-01 -1.21e-02 9.88e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 8.99e-01 1.90e-02 9.88e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 8.99e-01 9.42e-03 9.88e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 8.99e-01 -3.27e-02 9.88e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 9.04e-01 -2.10e-02 9.93e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 9.06e-01 1.36e-02 9.94e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 9.06e-01 3.04e-02 9.94e-01
REACTOME RMTS METHYLATE HISTONE ARGININES 72 9.10e-01 7.68e-03 9.95e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 9.11e-01 -1.95e-02 9.95e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 9.11e-01 9.74e-03 9.95e-01
REACTOME METABOLISM OF RNA 675 9.13e-01 2.47e-03 9.95e-01
REACTOME COLLAGEN FORMATION 88 9.13e-01 6.75e-03 9.95e-01
REACTOME HOMOLOGY DIRECTED REPAIR 132 9.14e-01 -5.47e-03 9.95e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 9.14e-01 -1.67e-02 9.95e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 9.14e-01 1.77e-03 9.95e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 9.14e-01 -6.19e-03 9.95e-01
REACTOME PHASE 3 RAPID REPOLARISATION 8 9.14e-01 -2.19e-02 9.95e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 9.15e-01 1.60e-02 9.95e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 9.15e-01 1.86e-02 9.95e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 9.15e-01 1.65e-02 9.95e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 9.17e-01 -1.38e-02 9.96e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 9.18e-01 1.79e-02 9.96e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 9.18e-01 1.53e-02 9.96e-01
REACTOME RHOH GTPASE CYCLE 37 9.18e-01 9.73e-03 9.96e-01
REACTOME SARS COV 1 HOST INTERACTIONS 92 9.20e-01 6.04e-03 9.96e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 9.20e-01 8.01e-03 9.96e-01
REACTOME SIGNALING BY NTRK2 TRKB 25 9.22e-01 1.14e-02 9.96e-01
REACTOME PTK6 EXPRESSION 5 9.22e-01 2.52e-02 9.96e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 9.23e-01 9.49e-03 9.96e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 9.24e-01 1.42e-02 9.96e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 9.25e-01 2.06e-02 9.96e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 9.25e-01 9.56e-03 9.96e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 9.27e-01 1.77e-02 9.96e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 9.27e-01 -1.52e-02 9.96e-01
REACTOME SIGNALING BY EGFR IN CANCER 25 9.28e-01 -1.04e-02 9.96e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 9.29e-01 1.70e-02 9.96e-01
REACTOME INTERFERON SIGNALING 193 9.30e-01 3.67e-03 9.96e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 9.30e-01 1.53e-02 9.96e-01
REACTOME AMINE LIGAND BINDING RECEPTORS 40 9.30e-01 -7.99e-03 9.96e-01
REACTOME MET ACTIVATES PTPN11 5 9.30e-01 2.25e-02 9.96e-01
REACTOME FLT3 SIGNALING IN DISEASE 28 9.31e-01 -9.39e-03 9.96e-01
REACTOME SCAVENGING OF HEME FROM PLASMA 13 9.33e-01 -1.35e-02 9.96e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 9.35e-01 -3.72e-03 9.96e-01
REACTOME DAP12 SIGNALING 27 9.36e-01 -8.97e-03 9.96e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 9.36e-01 -1.64e-02 9.96e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 9.36e-01 -1.75e-02 9.96e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 9.37e-01 -8.90e-03 9.96e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 9.38e-01 -1.12e-02 9.96e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 9.39e-01 -9.19e-03 9.96e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 9.39e-01 -1.06e-02 9.96e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 9.40e-01 -1.94e-02 9.96e-01
REACTOME PROTEIN METHYLATION 17 9.40e-01 -1.05e-02 9.96e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 9.41e-01 -1.36e-02 9.96e-01
REACTOME HDL REMODELING 10 9.41e-01 -1.34e-02 9.96e-01
REACTOME TRANSLESION SYNTHESIS BY POLH 19 9.41e-01 9.73e-03 9.96e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 9.42e-01 1.27e-02 9.96e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 9.42e-01 1.32e-02 9.96e-01
REACTOME SERINE BIOSYNTHESIS 9 9.44e-01 -1.35e-02 9.96e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 9.44e-01 -4.59e-03 9.96e-01
REACTOME DUAL INCISION IN GG NER 39 9.45e-01 -6.36e-03 9.96e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 9.46e-01 4.30e-03 9.96e-01
REACTOME TRANSLESION SYNTHESIS BY POLK 17 9.48e-01 9.19e-03 9.96e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 9.48e-01 4.71e-03 9.96e-01
REACTOME SIGNALING BY FGFR4 40 9.49e-01 -5.88e-03 9.96e-01
REACTOME RHO GTPASES ACTIVATE CIT 19 9.49e-01 8.50e-03 9.96e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 9.49e-01 -3.83e-03 9.96e-01
REACTOME PHYSIOLOGICAL FACTORS 14 9.49e-01 -9.84e-03 9.96e-01
REACTOME METABOLISM OF STEROIDS 150 9.50e-01 2.99e-03 9.96e-01
REACTOME RAB GERANYLGERANYLATION 57 9.50e-01 4.76e-03 9.96e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 9.51e-01 -7.61e-03 9.96e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 9.52e-01 -1.24e-02 9.96e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 9.52e-01 4.90e-03 9.96e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 9.52e-01 1.31e-02 9.96e-01
REACTOME FLT3 SIGNALING 38 9.52e-01 -5.63e-03 9.96e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 9.52e-01 -1.09e-02 9.96e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 9.52e-01 -9.23e-03 9.96e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 9.53e-01 -4.70e-03 9.96e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 9.53e-01 9.72e-03 9.96e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 9.54e-01 8.66e-03 9.96e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 9.55e-01 9.92e-03 9.96e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 9.55e-01 5.86e-03 9.96e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 9.56e-01 1.44e-02 9.96e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 9.56e-01 7.16e-03 9.96e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 9.57e-01 -4.95e-03 9.96e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 9.58e-01 -1.37e-02 9.96e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 9.58e-01 4.52e-03 9.96e-01
REACTOME CELL CELL JUNCTION ORGANIZATION 64 9.58e-01 3.77e-03 9.96e-01
REACTOME SEROTONIN RECEPTORS 11 9.59e-01 -9.05e-03 9.96e-01
REACTOME DSCAM INTERACTIONS 11 9.59e-01 8.99e-03 9.96e-01
REACTOME CD28 CO STIMULATION 32 9.59e-01 -5.22e-03 9.96e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 9.60e-01 4.33e-03 9.96e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 9.61e-01 -6.54e-03 9.96e-01
REACTOME INTERFERON GAMMA SIGNALING 88 9.61e-01 -3.01e-03 9.96e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 9.62e-01 -4.73e-03 9.96e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 9.64e-01 -6.73e-03 9.96e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 9.65e-01 -1.02e-02 9.96e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 9.66e-01 7.47e-03 9.96e-01
REACTOME O LINKED GLYCOSYLATION 109 9.66e-01 -2.36e-03 9.96e-01
REACTOME ORGANIC CATION TRANSPORT 10 9.66e-01 -7.71e-03 9.96e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 9.66e-01 1.09e-02 9.96e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 9.67e-01 9.80e-03 9.96e-01
REACTOME DNA REPLICATION INITIATION 7 9.67e-01 -9.01e-03 9.96e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 9.68e-01 6.51e-03 9.96e-01
REACTOME REGULATION OF KIT SIGNALING 16 9.68e-01 5.86e-03 9.96e-01
REACTOME METABOLISM OF STEROID HORMONES 35 9.68e-01 -3.94e-03 9.96e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 9.70e-01 5.69e-03 9.96e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 9.70e-01 6.90e-03 9.96e-01
REACTOME ALK MUTANTS BIND TKIS 12 9.70e-01 -6.18e-03 9.96e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 9.70e-01 7.12e-03 9.96e-01
REACTOME ACYL CHAIN REMODELLING OF PI 17 9.71e-01 5.15e-03 9.96e-01
REACTOME ESTROGEN BIOSYNTHESIS 6 9.71e-01 8.61e-03 9.96e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 9.72e-01 2.67e-03 9.96e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 9.73e-01 -6.92e-03 9.96e-01
REACTOME MITOCHONDRIAL UNCOUPLING 5 9.74e-01 -8.40e-03 9.96e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 9.75e-01 8.20e-03 9.96e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 9.75e-01 3.12e-03 9.96e-01
REACTOME RETINOID CYCLE DISEASE EVENTS 11 9.75e-01 5.37e-03 9.96e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 9.76e-01 -1.84e-03 9.96e-01
REACTOME METABOLISM OF COFACTORS 19 9.76e-01 -3.96e-03 9.96e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 9.76e-01 6.44e-03 9.96e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 9.79e-01 -6.33e-03 9.96e-01
REACTOME SIGNALING BY ERBB4 57 9.80e-01 1.95e-03 9.96e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 9.80e-01 -3.13e-03 9.96e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 9.80e-01 -4.21e-03 9.96e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 9.80e-01 2.24e-03 9.96e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 9.80e-01 3.97e-03 9.96e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 9.82e-01 5.41e-03 9.97e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 9.82e-01 4.06e-03 9.97e-01
REACTOME COBALAMIN CBL METABOLISM 7 9.83e-01 4.61e-03 9.97e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 9.84e-01 3.44e-03 9.97e-01
REACTOME BASIGIN INTERACTIONS 24 9.85e-01 2.21e-03 9.97e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 9.86e-01 -1.54e-03 9.97e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 9.86e-01 4.56e-03 9.97e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 9.86e-01 1.97e-03 9.97e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 9.88e-01 2.01e-03 9.98e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 9.88e-01 9.47e-04 9.98e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 9.89e-01 -1.91e-03 9.99e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 9.91e-01 1.72e-03 9.99e-01
REACTOME PENTOSE PHOSPHATE PATHWAY 12 9.91e-01 -1.78e-03 9.99e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 9.93e-01 -9.32e-04 1.00e+00
REACTOME UBIQUINOL BIOSYNTHESIS 8 9.94e-01 1.64e-03 1.00e+00
REACTOME CS DS DEGRADATION 12 9.95e-01 1.07e-03 1.00e+00
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 9.95e-01 6.18e-04 1.00e+00
REACTOME RHOG GTPASE CYCLE 71 9.95e-01 -3.97e-04 1.00e+00
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 9.97e-01 6.79e-04 1.00e+00
REACTOME MET PROMOTES CELL MOTILITY 41 9.98e-01 -2.13e-04 1.00e+00
REACTOME SPHINGOLIPID METABOLISM 84 9.98e-01 1.27e-04 1.00e+00
REACTOME MRNA SPLICING 197 9.99e-01 7.73e-05 1.00e+00
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 9.99e-01 -8.97e-05 1.00e+00
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 9.99e-01 -1.11e-04 1.00e+00
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 9.99e-01 1.56e-04 1.00e+00
REACTOME ECM PROTEOGLYCANS 73 1.00e+00 -3.50e-05 1.00e+00


Detailed Gene set reports



REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 3.01e-21
s.dist 0.295
p.adjustANOVA 4.94e-18



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2T3 9844
OR4N2 9804
OR4K14 9790
OR7E24 9763
OR4C12 9747
OR4D1 9738
OR2H2 9732
OR5H1 9728
OR5K1 9716
OR52L1 9714
OR2L3 9692
OR9A4 9649
OR6C75 9613
OR14C36 9585
OR52E2 9570
OR10G9 9558
OR8D4 9543
OR2G2 9518
OR52K2 9515
OR51A2 9514

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2T3 9844.0
OR4N2 9804.0
OR4K14 9790.0
OR7E24 9763.0
OR4C12 9747.0
OR4D1 9738.0
OR2H2 9732.0
OR5H1 9728.0
OR5K1 9716.0
OR52L1 9714.0
OR2L3 9692.0
OR9A4 9649.0
OR6C75 9613.0
OR14C36 9585.0
OR52E2 9570.0
OR10G9 9558.0
OR8D4 9543.0
OR2G2 9518.0
OR52K2 9515.0
OR51A2 9514.0
OR10T2 9487.0
OR5T3 9446.0
OR56B1 9439.0
OR5M11 9412.0
OR5P2 9386.0
OR2AP1 9353.0
OR6K6 9347.0
OR10A6 9345.0
OR4K17 9329.0
OR52M1 9307.0
OR1I1 9297.0
OR11H6 9292.0
OR8B12 9279.0
OR10W1 9277.0
OR51V1 9250.0
OR52H1 9235.0
OR10G8 9218.0
OR8H1 9215.0
OR56B4 9203.0
OR4A16 9200.0
OR6T1 9198.0
OR1S1 9185.0
OR10K2 9177.0
OR1A2 9167.0
OR8G5 9166.0
OR2M2 9158.0
OR52A1 9141.0
OR1E1 9137.0
OR4S1 9120.0
OR8K5 9115.0
OR5T2 9102.0
OR51I2 9077.0
OR2J2 9054.0
OR52E8 8987.0
OR52B2 8985.0
OR10S1 8982.0
OR8G1 8973.0
OR52K1 8959.0
OR1A1 8952.0
OR2AT4 8947.0
OR13D1 8912.0
OR2B2 8909.0
OR4K2 8901.0
OR2G6 8856.0
OR13C9 8839.0
OR5H15 8832.0
OR2B6 8821.0
OR5AP2 8820.0
OR7A5 8811.0
OR5H6 8807.0
OR8J1 8795.0
OR4M1 8793.0
OR51Q1 8771.0
OR12D2 8750.0
OR2A12 8747.0
OR5T1 8717.5
OR51D1 8646.0
OR14I1 8626.0
OR2A2 8621.0
OR52N1 8617.0
OR1L4 8591.0
OR2AK2 8586.0
OR51B4 8566.0
OR4D9 8557.0
OR56A4 8528.0
OR10AG1 8526.0
OR2F1 8510.0
OR4K1 8496.0
OR52E6 8495.0
OR4L1 8470.0
OR6C3 8451.0
OR5W2 8421.0
OR7D2 8388.0
OR56A1 8368.0
OR2A5 8362.0
OR5L1 8347.0
OR10A7 8318.0
GNG13 8304.0
OR1L1 8271.0
OR5J2 8263.0
OR10G4 8228.0
OR2S2 8174.0
OR5I1 8139.0
OR5H2 8085.0
OR56A3 8074.0
OR5D14 8025.0
OR6B3 8015.0
OR5B12 8011.0
OR51M1 8005.0
OR11G2 8003.0
OR1S2 7839.0
OR4B1 7827.0
OR2C1 7783.0
OR13C4 7752.0
OR2F2 7687.0
OR6F1 7642.0
OR10A5 7637.5
OR4D2 7488.0
OR2T4 7464.0
OR5V1 7438.0
OR7G1 7415.0
OR2T33 7393.0
OR4F6 7356.0
OR51L1 7345.0
RTP2 7275.0
OR2W1 7201.0
OR6S1 7135.0
OR6K3 7117.0
OR13G1 7112.0
OR5D18 7090.0
OR6C1 7062.0
OR4A15 7032.0
OR2L2 7000.0
OR3A2 6930.0
OR5AU1 6890.0
OR2B3 6800.0
OR1M1 6794.0
OR8D1 6635.0
OR8U1 6610.0
OR9Q2 6584.0
OR6C68 6501.0
OR52N2 6483.0
OR4K13 6442.0
OR2M3 6425.0
OR10J5 6347.0
OR5D16 6286.0
OR51G1 6282.0
OR4C16 6210.0
OR13F1 6141.0
OR8J3 6125.0
OR51B5 6124.0
OR4C45 6119.0
OR5AC2 6034.0
OR5K2 5978.0
OR2W3 5883.0
OR10K1 5815.0
OR6C70 5738.0
OR5AN1 5680.0
OR10G2 5528.0
OR2L8 5343.0
OR14A16 5332.0
OR2H1 5293.0
OR6C2 5227.0
OR51F2 5216.0
OR7A10 5089.0
OR4N5 5053.0
OR4A47 5041.0
OR4K5 5038.0
OR6X1 4986.0
OR2A14 4968.0
OR2K2 4953.0
OR8K1 4889.0
OR2L13 4872.0
OR4C6 4814.0
OR51E2 4795.0
OR5F1 4683.0
OR7G2 4678.0
OR6C6 4531.0
OR5M1 4491.0
OR5C1 4370.0
OR7C2 4320.0
OR6B2 4302.0
OR1G1 3953.0
OR9Q1 3879.0
OR5P3 3852.0
OR5D13 3800.0
OR2T27 3781.0
OR52I1 3617.0
OR4X1 3382.0
OR4C46 3341.0
OR13C8 3032.0
OR11L1 3019.0
OR1D2 3017.0
OR8U8 2926.0
OR2T8 2831.0
OR2C3 2640.0
OR4C15 2590.0
OR51S1 2566.0
OR5M8 2537.0
OR56A5 2524.0
OR52E4 2491.0
OR13C3 2478.0
OR6P1 2474.0
OR10H4 2428.0
OR13C2 2394.0
OR1C1 2366.0
OR11H4 2307.0
OR13J1 2158.0
OR10A2 2039.0
OR7D4 2015.0
OR13A1 1969.0
OR2G3 1865.0
OR10A3 1598.0
OR2B11 1447.0
OR2M5 1417.0
OR51A7 1317.0
OR2L5 1090.0
OR2AG2 1004.0
OR10C1 992.0
OR6C74 915.0
OR2T6 769.0
LHX2 590.0
OR12D3 535.0
OR9G4 325.0
OR2T1 267.0
OR3A1 179.0
OR10J3 129.0
OR4D10 118.0
OR10G3 44.0
OR52A5 -125.0
OR8U3 -196.0
OR5B21 -210.0
OR52J3 -327.0
OR9K2 -831.0
OR52D1 -889.0
OR51B2 -969.0
OR5M10 -1060.0
OR2Z1 -1110.0
OR5L2 -1148.0
OR8S1 -1458.0
OR9A2 -1509.0
EBF1 -1555.0
REEP1 -1570.0
RTP1 -1778.0
OR8K3 -1814.0
OR1F1 -1968.0
ADCY3 -2066.0
OR1L3 -2175.0
OR1J1 -2602.0
OR10Q1 -2932.0
OR5AS1 -2975.0
OR4D11 -3016.0
OR5AR1 -3072.0
OR4X2 -3154.0
OR8A1 -3186.0
OR5B3 -3297.0
OR2Y1 -3513.0
OR52I2 -3530.0
GNAL -3536.0
OR10H5 -3672.0
OR1E2 -3766.0
OR8B4 -4067.0
OR8B2 -4071.0
OR6C76 -4447.0
OR10G7 -4494.0
ANO2 -4515.0
OR14J1 -4555.0
OR7C1 -4605.0
OR6K2 -4615.0
OR10X1 -4911.0
OR10H1 -4934.0
OR11A1 -4940.0
LDB1 -5029.0
OR6N2 -5268.0
OR8D2 -5319.0
OR51B6 -5385.0
OR6Y1 -5401.0
OR9I1 -5409.0
OR51I1 -5817.0
OR7A17 -5891.0
OR4D6 -5960.0
OR9G1 -6727.5
OR9G9 -6727.5
OR2AG1 -6791.0
OR1K1 -6844.0
CNGA4 -7075.0
OR51T1 -7110.0
CNGB1 -7201.0
OR51E1 -7282.0
OR2V2 -7339.0
OR2AE1 -7484.0
OR51F1 -7885.0
OR6B1 -7894.0
OR1L8 -8179.0
OR5M3 -8244.0
OR1B1 -8246.0
OR2T11 -8254.0
OR4C3 -8340.0
OR5AK2 -8693.0
OR6C65 -8727.0
OR4F15 -8738.0
OR2D2 -8824.0
OR2M7 -8842.0
OR2V1 -8853.0
OR6C4 -8982.0
OR6A2 -9093.0
OR4E2 -9319.0
OR5A2 -9420.0
GNB1 -9556.0
OR5B2 -9626.0
OR10H3 -9637.0
OR10AD1 -9723.0
OR2T12 -9783.0
OR52R1 -9789.0
OR1Q1 -9793.0
OR5B17 -9852.0
OR1J2 -10005.0
OR4A5 -10082.0
OR1L6 -10239.0
OR5K3 -10380.0
OR7G3 -10473.0
OR10H2 -10515.0
OR8B8 -10518.0
OR6Q1 -10606.0
OR51G2 -10638.0
OR52B6 -10657.0
OR1N1 -10791.0
OR5A1 -10847.0
OR6V1 -10854.0
OR1J4 -10867.0
OR5M9 -10890.0
OR5K4 -10906.0
OR52W1 -11010.0
OR10V1 -11281.0
OR3A3 -11316.0
OR10A4 -11344.0
OR6M1 -11366.0
OR2M4 -11367.0
OR4K15 -11442.0
OR2D3 -11517.0
OR10J1 -11520.0
OR4D5 -11604.0
OR6N1 -11777.0
OR1N2 -11943.0
OR8I2 -11989.0
OR10Z1 -12027.0
OR10P1 -12070.0
OR8H3 -12100.0


REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION
1581
set REACTOME_SENSORY_PERCEPTION
setSize 555
pANOVA 5.33e-15
s.dist 0.194
p.adjustANOVA 4.38e-12



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR2T3 9844
OR4N2 9804
OR4K14 9790
OR7E24 9763
OR4C12 9747
OR4D1 9738
OR2H2 9732
OR5H1 9728
OR5K1 9716
OR52L1 9714
OR2L3 9692
OR9A4 9649
OR6C75 9613
OR14C36 9585
OR52E2 9570
OR10G9 9558
OR8D4 9543
OR2G2 9518
OR52K2 9515
OR51A2 9514

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR2T3 9844.0
OR4N2 9804.0
OR4K14 9790.0
OR7E24 9763.0
OR4C12 9747.0
OR4D1 9738.0
OR2H2 9732.0
OR5H1 9728.0
OR5K1 9716.0
OR52L1 9714.0
OR2L3 9692.0
OR9A4 9649.0
OR6C75 9613.0
OR14C36 9585.0
OR52E2 9570.0
OR10G9 9558.0
OR8D4 9543.0
OR2G2 9518.0
OR52K2 9515.0
OR51A2 9514.0
OR10T2 9487.0
OR5T3 9446.0
OR56B1 9439.0
OR5M11 9412.0
OR5P2 9386.0
OR2AP1 9353.0
GRXCR2 9348.0
OR6K6 9347.0
OR10A6 9345.0
OR4K17 9329.0
OR52M1 9307.0
OR1I1 9297.0
OR11H6 9292.0
OR8B12 9279.0
OR10W1 9277.0
OR51V1 9250.0
OR52H1 9235.0
GNGT1 9233.0
OR10G8 9218.0
OR8H1 9215.0
OR56B4 9203.0
OR4A16 9200.0
OR6T1 9198.0
OR1S1 9185.0
OR10K2 9177.0
GUCA1C 9173.0
OR1A2 9167.0
OR8G5 9166.0
OR2M2 9158.0
OR52A1 9141.0
OR1E1 9137.0
OR4S1 9120.0
OR8K5 9115.0
OR5T2 9102.0
OR51I2 9077.0
AKR1C4 9073.0
OR2J2 9054.0
OR52E8 8987.0
OR52B2 8985.0
OR10S1 8982.0
OR8G1 8973.0
OR52K1 8959.0
TAS2R43 8953.0
OR1A1 8952.0
OR2AT4 8947.0
AKR1B10 8929.0
OR13D1 8912.0
OR2B2 8909.0
OR4K2 8901.0
OR2G6 8856.0
OR13C9 8839.0
OR5H15 8832.0
OR2B6 8821.0
OR5AP2 8820.0
OR7A5 8811.0
OR5H6 8807.0
OR8J1 8795.0
OR4M1 8793.0
OR51Q1 8771.0
OR12D2 8750.0
OR2A12 8747.0
OR5T1 8717.5
OR51D1 8646.0
TAS2R40 8629.0
OR14I1 8626.0
OR2A2 8621.0
OR52N1 8617.0
OR1L4 8591.0
OR2AK2 8586.0
OR51B4 8566.0
OR4D9 8557.0
TTR 8552.0
OR56A4 8528.0
OR10AG1 8526.0
TAS2R7 8520.0
OR2F1 8510.0
AKR1C3 8498.0
OR4K1 8496.0
OR52E6 8495.0
OR4L1 8470.0
OR6C3 8451.0
OR5W2 8421.0
TAS2R16 8406.0
OR7D2 8388.0
APOC3 8381.0
OR56A1 8368.0
OR2A5 8362.0
OR5L1 8347.0
OR10A7 8318.0
GNG13 8304.0
OR1L1 8271.0
OR5J2 8263.0
OR10G4 8228.0
OR2S2 8174.0
OR5I1 8139.0
OTOP1 8133.0
OR5H2 8085.0
OR56A3 8074.0
OR5D14 8025.0
OR6B3 8015.0
OR5B12 8011.0
OR51M1 8005.0
OR11G2 8003.0
TAS2R1 7846.0
TAS2R41 7845.0
OR1S2 7839.0
OR4B1 7827.0
OR2C1 7783.0
OR13C4 7752.0
OR2F2 7687.0
LRRC52 7686.0
STRA6 7670.0
OR6F1 7642.0
OR10A5 7637.5
PCDH15 7631.0
APOA2 7616.0
OTOGL 7604.0
OR4D2 7488.0
OR2T4 7464.0
OR5V1 7438.0
OR7G1 7415.0
OR2T33 7393.0
OR4F6 7356.0
OR51L1 7345.0
SDC3 7321.0
RTP2 7275.0
CLPS 7225.0
OR2W1 7201.0
OR6S1 7135.0
OR6K3 7117.0
OR13G1 7112.0
OR5D18 7090.0
OR6C1 7062.0
OR4A15 7032.0
VAMP2 7018.0
OR2L2 7000.0
RBP2 6937.0
OR3A2 6930.0
OR5AU1 6890.0
OR2B3 6800.0
OR1M1 6794.0
GPC5 6734.0
SCN9A 6699.0
SCN2A 6681.0
OR8D1 6635.0
OR8U1 6610.0
OR9Q2 6584.0
TAS2R13 6543.0
CYP4V2 6530.0
OR6C68 6501.0
OR52N2 6483.0
METAP1 6481.0
OR4K13 6442.0
OR2M3 6425.0
OR10J5 6347.0
OR5D16 6286.0
OR51G1 6282.0
OR4C16 6210.0
OR13F1 6141.0
OR8J3 6125.0
OR51B5 6124.0
OR4C45 6119.0
OR5AC2 6034.0
CHRNA9 6031.0
OR5K2 5978.0
XIRP2 5909.0
OR2W3 5883.0
DHRS9 5818.0
OR10K1 5815.0
TMC1 5747.0
OR6C70 5738.0
WHRN 5697.0
OR5AN1 5680.0
APOA1 5670.0
SDC2 5633.0
PLCB2 5627.0
OR10G2 5528.0
TAS2R31 5495.0
SPTAN1 5469.0
SDC4 5466.0
GUCA1A 5453.0
OR2L8 5343.0
OR14A16 5332.0
GUCY2D 5315.0
OR2H1 5293.0
TRPM4 5281.0
OR6C2 5227.0
OR51F2 5216.0
RBP4 5165.0
OR7A10 5089.0
OR4N5 5053.0
OR4A47 5041.0
OR4K5 5038.0
EZR 5006.0
OR6X1 4986.0
OR2A14 4968.0
OR2K2 4953.0
OR8K1 4889.0
TAS2R46 4886.0
OR2L13 4872.0
OR4C6 4814.0
OR51E2 4795.0
EPS8 4707.0
OR5F1 4683.0
OR7G2 4678.0
DHRS3 4660.0
GPC6 4551.0
OR6C6 4531.0
OR5M1 4491.0
CAPZA2 4484.0
PJVK 4372.0
OR5C1 4370.0
OR7C2 4320.0
OR6B2 4302.0
LRAT 4024.0
OR1G1 3953.0
OR9Q1 3879.0
OR5P3 3852.0
OR5D13 3800.0
OR2T27 3781.0
CNGA1 3716.0
MYO3B 3650.0
OR52I1 3617.0
MYO3A 3538.0
GRXCR1 3497.0
TMIE 3480.0
PRKCA 3430.0
OR4X1 3382.0
OR4C46 3341.0
SCN1B 3190.0
DNAJC5 3063.0
OR13C8 3032.0
OR11L1 3019.0
OR1D2 3017.0
ESPN 2988.0
PLB1 2966.0
OR8U8 2926.0
OR2T8 2831.0
GNB3 2797.0
TAS2R10 2681.0
SCN4B 2679.0
PCLO 2674.0
OR2C3 2640.0
OR4C15 2590.0
OR51S1 2566.0
OR5M8 2537.0
OR56A5 2524.0
OR52E4 2491.0
OR13C3 2478.0
OR6P1 2474.0
OR10H4 2428.0
CABP1 2426.0
OR13C2 2394.0
OR1C1 2366.0
OR11H4 2307.0
LRP2 2187.0
OR13J1 2158.0
GNAT3 2081.0
AKR1C1 2071.0
OR10A2 2039.0
OR7D4 2015.0
USH1C 1997.0
OR13A1 1969.0
OR2G3 1865.0
TAS2R3 1859.0
PLS1 1836.0
CAPZA1 1811.0
KCNMB1 1710.0
RDH12 1672.0
OR10A3 1598.0
NAPEPLD 1585.0
APOB 1554.0
OTOF 1507.0
KCNJ2 1504.0
OR2B11 1447.0
OR2M5 1417.0
OR51A7 1317.0
SCNN1G 1302.0
PNLIP 1203.0
TAS2R38 1092.0
OR2L5 1090.0
ATP2B1 1055.0
CACNB2 1042.0
OR2AG2 1004.0
OR10C1 992.0
OR6C74 915.0
TAS2R50 822.0
RHO 795.0
OR2T6 769.0
HSD17B6 682.0
LHX2 590.0
OR12D3 535.0
GRM1 371.0
RETSAT 365.0
RIPOR2 356.0
SCN3A 344.0
OR9G4 325.0
OR2T1 267.0
TAS2R4 247.0
OR3A1 179.0
OR10J3 129.0
OR4D10 118.0
OR10G3 44.0
SLC26A5 26.0
PRKCQ 10.0
AGRN -111.0
OR52A5 -125.0
OR8U3 -196.0
OR5B21 -210.0
OR52J3 -327.0
OTOG -458.0
GUCA1B -481.0
SCN2B -510.0
TPRN -656.0
LRP10 -658.0
GPC1 -659.0
TWF2 -690.0
RAB3A -698.0
OR9K2 -831.0
RCVRN -856.0
MYH9 -874.0
OR52D1 -889.0
NMT2 -925.0
OR51B2 -969.0
OR5M10 -1060.0
OR2Z1 -1110.0
OR5L2 -1148.0
RDH11 -1159.0
RPE65 -1257.0
OR8S1 -1458.0
ESPNL -1477.0
CIB2 -1486.0
OR9A2 -1509.0
RDX -1510.0
EBF1 -1555.0
REEP1 -1570.0
FNTA -1697.0
RTP1 -1778.0
RGS9BP -1782.0
OR8K3 -1814.0
OR1F1 -1968.0
TAS1R1 -1999.0
ADCY3 -2066.0
OR1L3 -2175.0
SNAP25 -2201.0
CALM1 -2218.0
CAMKMT -2240.0
KCNMA1 -2293.0
TWF1 -2296.0
TRPM5 -2298.0
KCNQ4 -2318.0
FSCN2 -2330.0
STRC -2416.0
ACTG1 -2441.0
FNTB -2447.0
RGS9 -2599.0
OR1J1 -2602.0
GRM4 -2612.0
TMC2 -2618.0
CABP2 -2903.0
OR10Q1 -2932.0
ATP2B2 -2938.0
OR5AS1 -2975.0
EPB41L3 -2978.0
OR4D11 -3016.0
OR5AR1 -3072.0
OR4X2 -3154.0
OR8A1 -3186.0
SLC17A8 -3264.0
OR5B3 -3297.0
CLIC5 -3313.0
APOE -3458.0
OR2Y1 -3513.0
OR52I2 -3530.0
GNAL -3536.0
CHRNA10 -3574.0
OR10H5 -3672.0
HSD17B1 -3694.0
OR1E2 -3766.0
LDLR -3854.0
MYO1C -3880.0
EPB41L1 -3958.0
OR8B4 -4067.0
OR8B2 -4071.0
MYO15A -4121.0
GRK4 -4122.0
BCO2 -4187.0
OR6C76 -4447.0
OR10G7 -4494.0
PDE6B -4495.0
ANO2 -4515.0
OR14J1 -4555.0
OR7C1 -4605.0
OR6K2 -4615.0
CTBP2 -4674.0
OR10X1 -4911.0
OR10H1 -4934.0
OR11A1 -4940.0
GNB5 -5001.0
HSPG2 -5023.0
LDB1 -5029.0
SCNN1D -5246.0
GRK7 -5259.0
OR6N2 -5268.0
OR8D2 -5319.0
KCNN2 -5359.0
SPTBN1 -5366.0
OR51B6 -5385.0
CACNA1D -5395.0
OR6Y1 -5401.0
OR9I1 -5409.0
OPN1SW -5563.0
PDE6A -5691.0
OR51I1 -5817.0
OR7A17 -5891.0
OR4D6 -5960.0
ITPR3 -6012.0
CDH23 -6221.0
RDH8 -6326.0
GSN -6341.0
LRP8 -6421.0
BSN -6422.0
CAPZB -6522.0
OR9G1 -6727.5
OR9G9 -6727.5
GPC2 -6775.0
OR2AG1 -6791.0
OR1K1 -6844.0
RBP1 -6846.0
SCNN1B -7074.0
CNGA4 -7075.0
ABCA4 -7103.0
OR51T1 -7110.0
TAS2R5 -7198.0
CNGB1 -7201.0
SDC1 -7206.0
OR51E1 -7282.0
LRP12 -7318.0
OR2V2 -7339.0
OR2AE1 -7484.0
LRP1 -7517.0
GNAT1 -7599.0
TAS2R14 -7755.0
METAP2 -7808.0
CALHM1 -7858.0
OR51F1 -7885.0
OR6B1 -7894.0
TAS2R20 -8066.0
OR1L8 -8179.0
RDH10 -8242.0
OR5M3 -8244.0
OR1B1 -8246.0
OR2T11 -8254.0
OR4C3 -8340.0
GPIHBP1 -8426.0
SDR9C7 -8598.0
OR5AK2 -8693.0
OR6C65 -8727.0
OR4F15 -8738.0
LHFPL5 -8774.0
OR2D2 -8824.0
OR2M7 -8842.0
OR2V1 -8853.0
OR6C4 -8982.0
LPL -8991.0
EPS8L2 -9018.0
MYO7A -9019.0
OR6A2 -9093.0
TAS1R2 -9220.0
SLC24A1 -9233.0
SCNN1A -9237.0
RLBP1 -9265.0
OR4E2 -9319.0
OR5A2 -9420.0
ACTB -9512.0
GNB1 -9556.0
OR5B2 -9626.0
OR10H3 -9637.0
NMT1 -9643.0
OR10AD1 -9723.0
USH1G -9735.0
CACNA2D2 -9772.0
OR2T12 -9783.0
OR52R1 -9789.0
OR1Q1 -9793.0
OR5B17 -9852.0
OR1J2 -10005.0
OR4A5 -10082.0
TRIOBP -10098.0
OR1L6 -10239.0
TAS2R30 -10267.0
OR5K3 -10380.0
OR7G3 -10473.0
OR10H2 -10515.0
OR8B8 -10518.0
OR6Q1 -10606.0
OR51G2 -10638.0
OR52B6 -10657.0
STX1A -10770.0
OR1N1 -10791.0
OR5A1 -10847.0
OR6V1 -10854.0
OR1J4 -10867.0
OR5M9 -10890.0
OR5K4 -10906.0
APOA4 -10916.0
TAS2R8 -10933.0
PDE6G -10949.0
RBP3 -10960.0
OR52W1 -11010.0
BCO1 -11017.0
OR10V1 -11281.0
OR3A3 -11316.0
OR10A4 -11344.0
OR6M1 -11366.0
OR2M4 -11367.0
CALHM3 -11378.0
APOM -11410.0
OR4K15 -11442.0
SAG -11465.0
OR2D3 -11517.0
OR10J1 -11520.0
GRK1 -11565.0
OR4D5 -11604.0
OR6N1 -11777.0
RDH5 -11781.0
APOC2 -11825.0
RDH16 -11897.0
OR1N2 -11943.0
OR8I2 -11989.0
TAS1R3 -11995.0
OR10Z1 -12027.0
OR10P1 -12070.0
OR8H3 -12100.0
TAS2R39 -12134.0


REACTOME_DRUG_ADME

REACTOME_DRUG_ADME
1593
set REACTOME_DRUG_ADME
setSize 103
pANOVA 5.5e-05
s.dist 0.23
p.adjustANOVA 0.0275



Top enriched genes

Top 20 genes
GeneID Gene Rank
GSTA1 9821
ACSM2A 9672
UGT2B7 9321
UGT2B11 9149
TPMT 8869
UGT2B4 8860
BCHE 8810
SLC28A2 8760
SLC22A7 8616
NUDT15 8456
ADAL 8439
CYP2C8 8343
CYP2C9 8091
SLCO1B3 7984
ACSM2B 7925
UGT1A1 7905
SLCO1A2 7603
UGT2A1 7263
PCK1 7217
SLCO1B1 7092

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GSTA1 9821
ACSM2A 9672
UGT2B7 9321
UGT2B11 9149
TPMT 8869
UGT2B4 8860
BCHE 8810
SLC28A2 8760
SLC22A7 8616
NUDT15 8456
ADAL 8439
CYP2C8 8343
CYP2C9 8091
SLCO1B3 7984
ACSM2B 7925
UGT1A1 7905
SLCO1A2 7603
UGT2A1 7263
PCK1 7217
SLCO1B1 7092
UGT1A4 6875
NT5C2 6857
IMPDH2 6773
SLC22A8 6763
ABCC5 6754
PNP 6705
UGT1A3 6667
CYP3A4 6657
CYP2E1 6482
VAV2 6477
SLC22A2 6314
SULT1C4 6305
CYP2D6 6161
UGT1A5 5973
CES2 5889
PON1 5813
GSTP1 5685
UGT2A2 5460
SULT1A1 5451
ABCG2 5285
GLYAT 5228
HSD11B1 4956
ADK 4561
GLYATL2 4412
UGT1A8 4361
UGT1A10 4284
IMPDH1 4184
UGT3A1 3842
SLC29A3 3183
SLC22A3 3100
GLYATL3 3069
UGT1A9 2869
ALB 2817
UGT1A7 2362
GMPS 2322
BSG 2309
AKR1C1 2071
UGT1A6 1838
ACSM4 953
ABCB1 739
SLC22A1 -249
VAV3 -291
NAT1 -326
GLYATL1 -809
UGT2A3 -1637
ADA -2131
SLC29A2 -2141
UGT3A2 -2226
HSD11B2 -2765
NAT2 -2929
PON3 -2940
ACY1 -3227
ADH1A -3246
GGT5 -3453
CES1 -3601
GSTM1 -3687
ABCC4 -4008
GGT7 -4730
ABCC1 -4831
NME1 -4863
GSTA2 -4941
NME2 -5054
SLC29A1 -5092
ACSM5 -5567
CYP2C19 -5754
UGT2B17 -5879
SULT2A1 -6048
GUK1 -6113
SERPINA6 -6224
UGT2B15 -6262
GGT1 -6273
SLC16A1 -6370
SLC28A3 -6795
ITPA -7128
VAV1 -7135
ABCC2 -7212
ABCC3 -7575
CNDP2 -7891
XDH -8734
SLCO2B1 -9203
RAC1 -9215
GGT6 -9430
SULT1E1 -11021


REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME
1595
set REACTOME_ASPIRIN_ADME
setSize 42
pANOVA 6.7e-05
s.dist 0.355
p.adjustANOVA 0.0275



Top enriched genes

Top 20 genes
GeneID Gene Rank
ACSM2A 9672
UGT2B7 9321
UGT2B11 9149
UGT2B4 8860
BCHE 8810
SLC22A7 8616
CYP2C8 8343
CYP2C9 8091
ACSM2B 7925
UGT1A1 7905
UGT2A1 7263
UGT1A4 6875
UGT1A3 6667
CYP3A4 6657
CYP2E1 6482
CYP2D6 6161
UGT1A5 5973
CES2 5889
UGT2A2 5460
GLYAT 5228

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ACSM2A 9672
UGT2B7 9321
UGT2B11 9149
UGT2B4 8860
BCHE 8810
SLC22A7 8616
CYP2C8 8343
CYP2C9 8091
ACSM2B 7925
UGT1A1 7905
UGT2A1 7263
UGT1A4 6875
UGT1A3 6667
CYP3A4 6657
CYP2E1 6482
CYP2D6 6161
UGT1A5 5973
CES2 5889
UGT2A2 5460
GLYAT 5228
GLYATL2 4412
UGT1A8 4361
UGT3A1 3842
GLYATL3 3069
UGT1A9 2869
ALB 2817
UGT1A7 2362
BSG 2309
UGT1A6 1838
ACSM4 953
GLYATL1 -809
UGT2A3 -1637
UGT3A2 -2226
CES1 -3601
ACSM5 -5567
CYP2C19 -5754
UGT2B17 -5879
UGT2B15 -6262
SLC16A1 -6370
ABCC2 -7212
ABCC3 -7575
SLCO2B1 -9203


REACTOME_KERATINIZATION

REACTOME_KERATINIZATION
1073
set REACTOME_KERATINIZATION
setSize 210
pANOVA 0.000102
s.dist 0.156
p.adjustANOVA 0.0334



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRTAP9-1 9759
KRTAP4-5 9690
KRTAP19-1 9680
KRTAP4-7 9659
KRTAP12-4 9655
KRTAP13-1 9652
KRT33B 9624
LCE1F 9602
LCE2D 9598
KRTAP25-1 9538
KRTAP4-11 9523
RPTN 9491
KRTAP1-4 9454
KRTAP1-5 9448
DSC1 9402
KRT17 9350
KRT36 9334
KRTAP24-1 9316
KRTAP22-1 9111
KRTAP20-2 9101

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRTAP9-1 9759
KRTAP4-5 9690
KRTAP19-1 9680
KRTAP4-7 9659
KRTAP12-4 9655
KRTAP13-1 9652
KRT33B 9624
LCE1F 9602
LCE2D 9598
KRTAP25-1 9538
KRTAP4-11 9523
RPTN 9491
KRTAP1-4 9454
KRTAP1-5 9448
DSC1 9402
KRT17 9350
KRT36 9334
KRTAP24-1 9316
KRTAP22-1 9111
KRTAP20-2 9101
LCE4A 9065
KRTAP1-3 9052
KRTAP5-1 9041
SPRR3 9029
KRTAP10-12 8990
KRTAP4-4 8968
KRTAP9-6 8962
KRTAP6-2 8954
KRTAP16-1 8928
SPINK9 8910
KRTAP5-11 8883
KRTAP9-4 8853
LCE1C 8753
KRT31 8723
KRTAP5-3 8711
KRT23 8697
KRTAP2-1 8645
KRTAP9-9 8531
KRTAP5-7 8523
KRTAP5-8 8468
SPRR2G 8433
PRSS8 8427
KRTAP4-3 8410
KRTAP6-3 8395
SPRR2F 8350
KRTAP12-3 8339
LIPK 8311
LCE2A 8252
KRT79 8243
KRTAP10-1 8231
KRTAP27-1 8207
KRT81 8203
KRT14 7908
KRT15 7817
KRTAP19-7 7704
LELP1 7664
KRT6A 7648
KRTAP19-2 7579
SPINK5 7559
KRTAP9-2 7545
KRTAP4-6 7510
KRTAP2-3 7507
KRTAP6-1 7401
KRTAP19-6 7184
KRT34 7068
KRT10 6968
LCE1A 6958
KRT19 6826
KRTAP5-10 6784
DSG1 6486
KRTAP5-4 6429
KRT86 6407
CSTA 6356
KRT39 6324
KRT9 6291
KRTAP19-5 6281
DSG2 6223
KRTAP23-1 6200
CAPNS1 6085
KRTAP21-1 6023
DSG3 6015
LCE3E 5968
LCE3D 5923
KRTAP17-1 5880
KRT25 5297
KRT24 5140
ST14 5005
KRTAP21-2 4403
KRT20 4022
KRTAP10-2 3942
PCSK6 3778
KRT37 3686
DSG4 3680
KLK14 3301
KAZN 3276
KRTAP5-2 3264
DSP 3213
SPRR1B 3055
KRTAP21-3 2878
KRT1 2725
KRTAP3-1 2596
PI3 2548
KRTAP2-2 2427
KRTAP19-8 2280
KRT13 2139
KRTAP2-4 2059
KRTAP4-2 2033
KRTAP9-3 1952
KRTAP10-4 1776
KRTAP13-3 1747
KRTAP12-1 1599
KLK12 1521
LCE3B 1483
KLK13 1360
KRT73 1279
SPRR2D 1112
PKP4 1033
TCHH 817
IVL 657
KRT6B 600
PERP -49
PPL -201
KRT77 -494
KRTAP19-3 -875
CASP14 -1181
KRTAP29-1 -1423
KRT82 -1430
SPRR2A -1924
KRTAP8-1 -2323
KRTAP4-8 -2719
KRTAP3-3 -2727
LCE2C -2843
CELA2A -3177
KRT80 -3250
KRT27 -3257
CDSN -4206
KRTAP20-1 -4211
EVPL -4417
KRT40 -4480
KRTAP26-1 -4503
LCE6A -4526
CAPN1 -4567
PKP3 -4661
FLG -4759
KRT33A -4825
KRT35 -4833
KRT6C -5219
KRTAP11-1 -5269
KRT4 -5682
KRTAP10-3 -6007
PKP1 -6036
KRT74 -6069
KRT71 -6129
KRT7 -6161
KRTAP4-1 -6330
KRTAP12-2 -6457
LCE1E -6506
KRT12 -6633
LCE3A -6839
KRT5 -6899
KRT38 -7063
LCE5A -7163
LIPM -7298
KRT85 -7750
KRT76 -7896
KRT3 -7921
KRTAP10-9 -8337
DSC2 -8349
PKP2 -8418
KLK8 -8492
KRTAP1-1 -8565
DSC3 -8608
KRT78 -8639
SPRR1A -8878
KRT8 -8959
KRT18 -9148
KRTAP5-5 -9375
KLK5 -9429
KRT2 -9499
LIPN -9601
TGM5 -9674
KRTAP19-4 -9934
SPINK6 -10006
KRTAP3-2 -10077
TGM1 -10248
JUP -10356
KRT16 -10400
KRTAP13-4 -10429
KRT84 -10510
KRT32 -10625
LCE2B -10731
KRTAP10-8 -10813
KRT28 -10833
KRT75 -10914
KRT26 -10925
KRTAP13-2 -11040
LCE1B -11113
KRT83 -11183
KRTAP10-11 -11184
KRTAP10-10 -11207
FURIN -11356
LIPJ -11497
KRTAP10-7 -11534
KRTAP10-5 -11585
KRT72 -11586
SPRR2E -11679
KRTAP15-1 -11708
KRTAP10-6 -11745
KRTAP5-6 -11804
KRTAP5-9 -11829


REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
601
set REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize 188
pANOVA 0.000178
s.dist -0.159
p.adjustANOVA 0.0435



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
C5AR1 -11866
CCL1 -11821
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
PRLHR -11657
CCL22 -11631
CCL20 -11562
CCL27 -11529
CCL21 -11489
PRLH -11475
NPBWR2 -11472
CCL17 -11359
F2RL3 -11350
CCL5 -11216
NPFF -11062

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
C5AR1 -11866
CCL1 -11821
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
PRLHR -11657
CCL22 -11631
CCL20 -11562
CCL27 -11529
CCL21 -11489
PRLH -11475
NPBWR2 -11472
CCL17 -11359
F2RL3 -11350
CCL5 -11216
NPFF -11062
NTSR1 -10955
CCL25 -10815
QRFP -10790
AVPR1B -10777
RLN3 -10750
PMCH -10662
MLN -10613
EDN2 -10602
EDN1 -10553
AGT -10501
FPR2 -10297
MC2R -10167
GALR2 -9968
CCL16 -9832
SSTR3 -9823
NMB -9814
CCL2 -9572
GALR1 -9378
GALR3 -9062
CXCL12 -9046
TRHR -9009
UTS2B -8942
NMUR2 -8845
MC1R -8833
CCR6 -8763
CCRL2 -8698
CXCL9 -8684
C3 -8646
F2RL2 -8434
NTSR2 -8395
ECE2 -8374
CXCL1 -8270
NMU -8039
NPY -8006
GPER1 -7976
XCL2 -7765
GPR37L1 -7701
EDNRB -7524
CXCL10 -7516
MC5R -7373
XCL1 -7299
POMC -7216
NMBR -7158
CXCR1 -7149
CCR9 -7125
CCL3 -7010
OXTR -7003
F2 -6935
PNOC -6815
TAC1 -6659
NPFFR1 -6454
GAL -6440
PROK2 -6373
KISS1R -6294
PROKR1 -6256
CXCR6 -6210
NPBWR1 -6088
OPRL1 -5782
BDKRB2 -5581
CXCL3 -5574
NPY2R -5527
NPY1R -5436
CXCL16 -5320
F2R -5315
CCR7 -5215
HCRT -5142
TRH -5141
PF4 -5097
CCK -5072
CXCL8 -5015
PSAP -4848
SSTR2 -4815
GHSR -4783
ACKR2 -4750
APLNR -4704
AGTR1 -4507
PPY -4028
KEL -3896
SSTR5 -3820
CXCL5 -3819
KNG1 -3701
PYY -3696
RXFP2 -3654
C5 -3568
CXCL2 -3269
CCR10 -3158
CCL23 -3102
ECE1 -2747
KISS1 -2619
CXCL11 -2171
EDN3 -2169
MCHR2 -2106
CXCR2 -1396
GRP -1392
SST -1272
AVPR1A -1147
TACR2 -974
GHRL -634
OPRK1 -463
NPSR1 -142
CCKBR 157
CCL13 294
TACR3 542
APP 650
NMS 733
MCHR1 785
CXCR4 937
CX3CL1 1134
QRFPR 1286
PPBP 1287
PROKR2 1536
HCRTR1 1663
SSTR1 1682
TACR1 1984
PENK 2034
MC4R 2121
C5AR2 2217
MC3R 2635
INSL3 2827
NTS 3035
RXFP3 3180
F2RL1 3211
EDNRA 3638
MLNR 3642
PDYN 3744
CORT 4004
CXCL6 4122
HCRTR2 4223
ANXA1 4428
NPY5R 4456
NPW 4681
CCR5 4925
NPFFR2 5060
CCR2 5061
HEBP1 5104
CCL7 5153
NLN 5474
RXFP1 5826
CCR4 5988
BDKRB1 6068
ACKR1 6100
XCR1 6142
OPRM1 6259
C3AR1 6366
SSTR4 6374
GPR37 6420
TAC3 6521
CCR3 6817
SAA1 6821
ACKR4 6953
UTS2R 7218
PROK1 7248
ACKR3 7281
CCKAR 7287
INSL5 7358
FPR3 7458
UTS2 7913
NPS 7990
CCR8 7991
CCL11 8186
OPRD1 8483
CXCL13 8489
CCL28 8578
CCR1 9046
NPB 9157
OXT 9243
RLN2 9437
FPR1 9622


REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 0.000186
s.dist -0.102
p.adjustANOVA 0.0435



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -12097
ADGRG3 -12067
DEFA4 -12001
S100P -11981
CFD -11977
CTSD -11960
MMP8 -11877
C5AR1 -11866
SIGLEC14 -11858
CEACAM3 -11855
CAMP -11850
TARM1 -11733
PRSS3 -11721
RAB44 -11594
CD300A -11511
ARHGAP9 -11498
PYCARD -11396
S100A7 -11375
ATP8B4 -11345
SLC15A4 -11209

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -12097
ADGRG3 -12067
DEFA4 -12001
S100P -11981
CFD -11977
CTSD -11960
MMP8 -11877
C5AR1 -11866
SIGLEC14 -11858
CEACAM3 -11855
CAMP -11850
TARM1 -11733
PRSS3 -11721
RAB44 -11594
CD300A -11511
ARHGAP9 -11498
PYCARD -11396
S100A7 -11375
ATP8B4 -11345
SLC15A4 -11209
TYROBP -11180
NBEAL2 -11161
ATP6V0C -11115
SLC2A3 -11095
BIN2 -11074
CD63 -10939
SERPINB3 -10923
BPI -10893
COTL1 -10868
FCER1G -10848
CTSG -10820
TRPM2 -10804
HBB -10802
DGAT1 -10797
NFAM1 -10787
PGLYRP1 -10767
UNC13D -10743
CEACAM8 -10683
PGAM1 -10674
STK10 -10664
ITGB2 -10658
AGPAT2 -10656
PADI2 -10645
TNFRSF1B -10604
TNFAIP6 -10592
AGL -10581
QPCT -10567
TICAM2 -10566
NAPRT -10557
C1orf35 -10523
CHIT1 -10514
NHLRC3 -10497
STK11IP -10482
TIMP2 -10468
ALDOC -10417
JUP -10356
AP1M1 -10347
CST3 -10338
B4GALT1 -10307
MCEMP1 -10303
FPR2 -10297
ORMDL3 -10149
ACTR1B -10070
ELANE -10053
RHOA -9958
SYNGR1 -9921
APAF1 -9883
SURF4 -9879
RAP1A -9865
ATP6V0A1 -9864
PSMD2 -9860
SIGLEC9 -9859
SERPINA1 -9764
FCGR3B -9706
ADAM8 -9668
PRG3 -9592
ITGAX -9524
ALAD -9523
MGAM -9436
PRKCD -9415
GLIPR1 -9346
RAC1 -9215
TOLLIP -9202
RAP2B -9161
PLD1 -9056
GRN -8983
RAB4B -8961
CD177 -8954
HSPA1A -8908
CYFIP1 -8904
PDXK -8899
DPP7 -8874
DBNL -8866
BRI3 -8854
PIGR -8840
MPO -8729
UBR4 -8675
CEACAM6 -8658
C3 -8646
PRTN3 -8620
ITGAL -8612
NPC2 -8588
AMPD3 -8571
RNASET2 -8546
TRAPPC1 -8509
ARSA -8494
LCN2 -8386
ATG7 -8373
NCSTN -8358
ASAH1 -8307
CXCL1 -8270
ILF2 -8204
CD14 -8158
RAB27A -8044
HSP90AA1 -7947
KCNAB2 -7911
NIT2 -7890
SELL -7881
FUCA1 -7880
ALOX5 -7874
PFKL -7797
AZU1 -7739
RAB6A -7690
CAP1 -7578
PSMD11 -7547
FGR -7507
NDUFC2 -7469
PTPN6 -7453
GSDMD -7410
RHOG -7357
ADGRE5 -7300
S100A8 -7218
CXCR1 -7149
LPCAT1 -7123
HGSNAT -7011
PSMA2 -6980
LRG1 -6930
ACAA1 -6860
MAPK1 -6855
ANPEP -6766
TMC6 -6752
S100A9 -6715
LTF -6677
SLC2A5 -6662
ATP8A1 -6656
GLB1 -6602
CHI3L1 -6574
CYBA -6497
TLR2 -6469
CTSZ -6435
ARHGAP45 -6398
SIRPA -6355
GSN -6341
CPNE3 -6252
LTA4H -6124
AOC1 -6090
CMTM6 -6070
PKP1 -6036
SERPINA3 -6024
CAB39 -6009
PSMD12 -5986
LILRB3 -5918
PLEKHO2 -5844
ARMC8 -5821
FAF2 -5676
VPS35L -5553
RAB37 -5494
SNAP23 -5479
AP2A2 -5471
PECAM1 -5360
KCMF1 -5276
CYB5R3 -5227
PA2G4 -5207
GPI -5199
PDAP1 -5190
NME2 -5054
DEGS1 -5048
CD55 -4995
PSMB7 -4950
TMBIM1 -4893
LAIR1 -4890
SNAP29 -4858
PSAP -4848
FUCA2 -4785
SCAMP1 -4722
MANBA -4702
CAPN1 -4567
IQGAP1 -4346
NCKAP1L -4254
LAMTOR2 -4242
FTH1 -4208
PAFAH1B2 -4201
CR1 -4159
PPIE -4085
CRISPLD2 -4065
ALDOA -3954
YPEL5 -3885
PTAFR -3879
C6orf120 -3857
RAB14 -3750
MAN2B1 -3697
LAMP1 -3691
CD47 -3690
XRCC5 -3684
HSP90AB1 -3657
PTGES2 -3602
DNAJC3 -3433
BST2 -3352
VAT1 -3298
AGA -3283
DSN1 -3259
CLEC4C -3254
CPNE1 -3248
MME -3058
SLPI -3030
GCA -2986
MVP -2937
RAB31 -2896
ALDH3B1 -2818
PTPRJ -2804
RAB5B -2791
CANT1 -2692
TMEM30A -2642
BST1 -2575
FLG2 -2567
PSMD1 -2565
RHOF -2506
PSMA5 -2478
PRDX6 -2457
IQGAP2 -2364
CEP290 -2347
DDOST -2327
OSCAR -2294
PSEN1 -2289
EEF2 -2288
HSPA6 -2248
PTPRN2 -2244
SNAP25 -2201
IRAG2 -2159
ABCA13 -2143
RAB24 -2071
ORM2 -2043
P2RX1 -2029
ANO6 -2015
ROCK1 -1979
SLC27A2 -1909
PLAC8 -1846
SERPINB6 -1844
CLEC12A -1816
SLC11A1 -1733
PKM -1732
ATP11B -1586
DOK3 -1533
CSNK2B -1517
CD59 -1495
CSTB -1478
AHSG -1468
ORM1 -1424
CXCR2 -1396
CTSB -1388
GPR84 -1352
PSMC2 -1220
MMP9 -1143
STOM -1107
HEBP2 -1006
NFASC -896
CD36 -823
RAB3A -698
ERP44 -576
CKAP4 -512
DYNC1H1 -361
HSPA8 -277
PSMB1 -252
PSMD6 -164
CNN2 -163
GNS -160
PRCP -78
TMEM63A -23
COMMD3 60
CHRNB4 62
DIAPH1 197
CTSA 229
SLC44A2 265
ATP11A 321
PTX3 360
TBC1D10C 384
CAND1 456
RAB5C 482
TOM1 611
TCIRG1 669
RAB10 677
CYSTM1 700
GYG1 846
CTSC 847
CTSS 873
ITGAV 884
CDK13 923
DYNLT1 939
RAB3D 941
IST1 943
GDI2 963
CCT8 991
MIF 1011
HEXB 1019
SERPINB1 1037
RAP1B 1146
ACTR2 1150
LAMTOR1 1185
PPBP 1287
DYNC1LI1 1352
FGL2 1381
PLAUR 1382
CLEC4D 1452
TXNDC5 1461
CD53 1501
PGM2 1669
TMEM179B 1743
OSTF1 1852
PSMD7 1876
MS4A3 1906
GHDC 1977
DERA 1988
VCL 2005
RAB7A 2021
PSMD13 2068
PYGB 2184
ACLY 2212
APRT 2228
NFKB1 2237
MLEC 2243
IGF2R 2291
CREG1 2313
HPSE 2373
MAPK14 2381
DNAJC13 2393
PGM1 2442
GM2A 2557
VCP 2571
RAB18 2624
KRT1 2725
GGH 2736
PYGL 2764
IDH1 2785
CEACAM1 2876
CCT2 2925
GALNS 3001
GOLGA7 3013
DNAJC5 3063
SVIP 3089
LGALS3 3124
CRACR2A 3194
RETN 3197
COMMD9 3199
DSP 3213
TCN1 3340
HLA-C 3383
PSMD3 3393
CD44 3576
PTPRC 3620
CDA 3634
DOCK2 3693
PLAU 3777
SERPINB12 3814
FABP5 3903
CPPED1 3979
HVCN1 4175
IMPDH1 4184
ARSB 4196
B2M 4202
FCAR 4247
FTL 4271
S100A11 4389
HSPA1B 4407
LRRC7 4420
CD33 4427
ADGRE3 4461
PSMD14 4464
NEU1 4480
LILRA3 4501
TSPAN14 4573
ITGAM 4609
EEF1A1 4629
SRP14 4631
DYNLL1 4803
HLA-A 4880
STBD1 5023
ARG1 5030
FRK 5097
ANXA2 5158
HK3 5182
VAMP8 5191
MGST1 5280
CD58 5356
SPTAN1 5469
CTSH 5536
KPNB1 5625
ATP6V1D 5637
CRISP3 5661
GSTP1 5685
LYZ 5857
STING1 5939
ADAM10 6078
SDCBP 6159
ATAD3B 6169
PPIA 6172
HP 6180
ENPP4 6209
APEH 6267
QSOX1 6277
NRAS 6299
ARPC5 6327
C3AR1 6366
DSG1 6486
MMP25 6574
PNP 6705
IMPDH2 6773
MNDA 6836
PSMC3 6871
CD93 6912
ARL8A 7008
HMOX2 7189
CLEC5A 7209
ACTR10 7272
LILRB2 7316
GAA 7318
PTPRB 7392
HMGB1 7457
ADA2 7459
GMFG 7513
OLFM4 7560
SLCO4C1 7569
GUSB 7814
SERPINB10 7878
SIRPB1 7881
TUBB 7975
PRG2 8033
XRCC6 8066
VAPA 8100
CAT 8250
ACP3 8268
FCGR2A 8403
EPX 8506
TTR 8552
HLA-B 8651
OLR1 8703
RNASE2 8706
A1BG 8726
TUBB4B 8798
CD68 8808
LAMTOR3 8881
VNN1 8888
COPB1 9003
S100A12 9057
RNASE3 9256
HRNR 9340
DSC1 9402
FOLR3 9428
SIGLEC5 9452
FPR1 9622
CALML5 9674


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 0.000722
s.dist -0.0631
p.adjustANOVA 0.148



Top enriched genes

Top 20 genes
GeneID Gene Rank
FCN1 -12097
ADGRG3 -12067
UBA7 -12055
DEFA4 -12001
S100P -11981
CFD -11977
SFTPA2 -11971
CTSD -11960
CD300LB -11924
SIGIRR -11917
MMP8 -11877
C5AR1 -11866
SIGLEC14 -11858
CEACAM3 -11855
CAMP -11850
PSMB11 -11786
TARM1 -11733
PRSS3 -11721
GNLY -11705
CCL22 -11631

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FCN1 -12097.0
ADGRG3 -12067.0
UBA7 -12055.0
DEFA4 -12001.0
S100P -11981.0
CFD -11977.0
SFTPA2 -11971.0
CTSD -11960.0
CD300LB -11924.0
SIGIRR -11917.0
MMP8 -11877.0
C5AR1 -11866.0
SIGLEC14 -11858.0
CEACAM3 -11855.0
CAMP -11850.0
PSMB11 -11786.0
TARM1 -11733.0
PRSS3 -11721.0
GNLY -11705.0
CCL22 -11631.0
FCN2 -11618.0
REG3G -11598.0
RAB44 -11594.0
CD300A -11511.0
ARHGAP9 -11498.0
ATP6V1E2 -11469.0
PYCARD -11396.0
TXK -11391.0
S100A7 -11375.0
CCL17 -11359.0
ATP8B4 -11345.0
PRKACA -11338.0
RAC2 -11337.0
CD4 -11333.0
PPP2CB -11323.0
DNM1 -11270.0
CRCP -11268.0
PTPN11 -11265.0
SLC15A4 -11209.0
MUC5AC -11192.0
TYROBP -11180.0
NBEAL2 -11161.0
ATP6V0C -11115.0
NLRC4 -11112.0
SLC2A3 -11095.0
DEFB123 -11089.0
BIN2 -11074.0
CD63 -10939.0
SERPINB3 -10923.0
ISG15 -10915.0
BPI -10893.0
COTL1 -10868.0
FCER1G -10848.0
TIFA -10834.0
VRK3 -10828.0
CTSG -10820.0
RELA -10818.0
TRPM2 -10804.0
HBB -10802.0
DGAT1 -10797.0
NFAM1 -10787.0
PGLYRP1 -10767.0
AGER -10754.0
UNC13D -10743.0
NLRX1 -10737.0
RNF135 -10732.0
IFNA14 -10712.0
ATP6V1B2 -10690.0
TRIM4 -10687.0
PSMB10 -10684.0
CEACAM8 -10683.0
PGAM1 -10674.0
STK10 -10664.0
ITGB2 -10658.0
AGPAT2 -10656.0
TREX1 -10649.0
PADI2 -10645.0
NOD2 -10630.0
TNFRSF1B -10604.0
TNFAIP6 -10592.0
AGL -10581.0
QPCT -10567.0
TICAM2 -10566.0
NAPRT -10557.0
C1orf35 -10523.0
CHIT1 -10514.0
C4BPA -10513.0
NHLRC3 -10497.0
DNM2 -10496.0
CD247 -10495.0
TRIM21 -10494.0
STK11IP -10482.0
TIMP2 -10468.0
IFNB1 -10465.0
KLRD1 -10456.0
CASP10 -10430.0
ALDOC -10417.0
IFNA7 -10371.0
JUP -10356.0
AP1M1 -10347.0
CST3 -10338.0
UBA3 -10315.0
B4GALT1 -10307.0
MCEMP1 -10303.0
FPR2 -10297.0
IKBIP -10287.0
ATP6V0E1 -10257.0
MUC12 -10173.0
ORMDL3 -10149.0
CLEC10A -10146.0
ATP6V0D1 -10139.0
RIGI -10108.0
DDX41 -10106.0
ACTR1B -10070.0
NFATC2 -10057.0
ELANE -10053.0
RASGRP4 -10017.0
NLRP3 -9992.0
RHOA -9958.0
SYNGR1 -9921.0
VTN -9903.0
APAF1 -9883.0
SURF4 -9879.0
RPS6KA1 -9870.0
RAP1A -9865.0
ATP6V0A1 -9864.0
PPP2R1A -9863.0
PSMD2 -9860.0
SIGLEC9 -9859.0
NCF4 -9857.0
PSMD4 -9796.0
SERPINA1 -9764.0
FCGR3B -9706.0
ARPC4 -9671.0
ADAM8 -9668.0
MAPK3 -9613.0
PRG3 -9592.0
MAP2K3 -9582.0
ATP6V1E1 -9547.0
ITGAX -9524.0
ALAD -9523.0
ACTB -9512.0
RASGRP2 -9507.0
ATP6V0B -9464.0
MGAM -9436.0
PRKCD -9415.0
MYO9B -9374.0
GLIPR1 -9346.0
RELB -9309.0
RAC1 -9215.0
TOLLIP -9202.0
S100A1 -9165.0
RAP2B -9161.0
CLEC4A -9140.0
EP300 -9135.0
PDPK1 -9058.0
PLD1 -9056.0
POLR2F -9035.0
TRIM56 -8984.0
GRN -8983.0
RAB4B -8961.0
CD177 -8954.0
HSPA1A -8908.0
CYFIP1 -8904.0
PDXK -8899.0
LAT2 -8882.0
DPP7 -8874.0
DBNL -8866.0
BRI3 -8854.0
PIGR -8840.0
CCR6 -8763.0
UBE2L6 -8742.0
MPO -8729.0
DEFB136 -8699.0
BPIFA1 -8694.0
PSMB5 -8682.0
ATP6V1C2 -8680.0
UBR4 -8675.0
ICAM3 -8662.0
CEACAM6 -8658.0
C3 -8646.0
PRTN3 -8620.0
ITGAL -8612.0
LGMN -8600.0
NPC2 -8588.0
MUC21 -8583.0
AMPD3 -8571.0
RNASET2 -8546.0
TRAPPC1 -8509.0
TAB1 -8507.0
ARSA -8494.0
RNF125 -8436.0
LCN2 -8386.0
IKBKE -8379.0
ATG7 -8373.0
NCSTN -8358.0
ASAH1 -8307.0
CARD9 -8274.0
CXCL1 -8270.0
MAPKAPK3 -8261.0
TKFC -8253.0
ATP6V0A2 -8252.0
ILF2 -8204.0
CD14 -8158.0
RIPK3 -8122.0
CASP2 -8121.0
PELI2 -8097.0
POLR1C -8068.0
HERC5 -8054.0
RAB27A -8044.0
SRC -8020.0
RNF216 -7990.0
PRKCSH -7989.0
MRE11 -7955.0
PIK3R4 -7954.0
HSP90AA1 -7947.0
RIPK1 -7931.0
KCNAB2 -7911.0
MAPK13 -7904.0
NIT2 -7890.0
SELL -7881.0
FUCA1 -7880.0
ALOX5 -7874.0
POLR3G -7871.0
TREM2 -7839.0
PFKL -7797.0
TNIP2 -7794.0
POLR2K -7746.0
AZU1 -7739.0
RAB6A -7690.0
PSMA3 -7677.0
CD209 -7648.0
COLEC11 -7603.0
CAP1 -7578.0
PSMD11 -7547.0
FGR -7507.0
PSME4 -7486.0
NDUFC2 -7469.0
TLR4 -7468.0
PTPN6 -7453.0
SHC1 -7445.0
ATP6V1C1 -7442.0
PLPP5 -7415.0
GSDMD -7410.0
POLR1D -7404.0
DEFB133 -7394.0
NLRC5 -7393.0
NCR2 -7376.0
TLR9 -7371.0
RHOG -7357.0
TLR1 -7330.0
ADGRE5 -7300.0
CNPY3 -7260.0
S100A8 -7218.0
TRAF3 -7207.0
CXCR1 -7149.0
RNASE8 -7136.0
VAV1 -7135.0
LPCAT1 -7123.0
TEC -7088.0
EPPIN -7033.0
POLR3H -7021.0
HGSNAT -7011.0
PSMA2 -6980.0
SIGLEC15 -6944.0
F2 -6935.0
LRG1 -6930.0
CARD11 -6885.0
WIPF1 -6883.0
PSMA1 -6876.0
CYLD -6869.0
ACAA1 -6860.0
MAPK1 -6855.0
ANPEP -6766.0
TMC6 -6752.0
CASP8 -6741.0
DTX4 -6736.0
S100A9 -6715.0
TLR10 -6693.0
PRKACG -6681.0
LTF -6677.0
SLC2A5 -6662.0
ATP8A1 -6656.0
TRIM25 -6635.0
GLB1 -6602.0
NCF2 -6592.0
CHI3L1 -6574.0
PLD3 -6532.0
BCL10 -6515.0
CYBA -6497.0
CREB1 -6475.0
TLR2 -6469.0
CTSZ -6435.0
EPPIN-WFDC6 -6406.0
ARHGAP45 -6398.0
ARPC1B -6371.0
PSMA6 -6365.0
SIRPA -6355.0
GSN -6341.0
PGLYRP2 -6269.0
CPNE3 -6252.0
CLEC4E -6238.0
DEFB134 -6237.0
CPN1 -6236.0
MYO5A -6222.0
LTA4H -6124.0
CPB2 -6118.0
AOC1 -6090.0
CMTM6 -6070.0
HCK -6054.0
PKP1 -6036.0
SERPINA3 -6024.0
ITPR3 -6012.0
CAB39 -6009.0
PSMD12 -5986.0
CRK -5923.0
LILRB3 -5918.0
RNASE6 -5882.0
PIN1 -5856.0
PLEKHO2 -5844.0
HRAS -5842.0
ARMC8 -5821.0
PLCG2 -5798.0
PIK3R2 -5785.0
MEFV -5770.0
DNM3 -5716.0
FAF2 -5676.0
LBP -5663.0
TLR6 -5647.0
CREBBP -5580.0
MUC20 -5557.0
PIK3CB -5554.0
VPS35L -5553.0
CD46 -5521.0
PSTPIP1 -5514.0
HMOX1 -5508.0
RAB37 -5494.0
SNAP23 -5479.0
AP2A2 -5471.0
GSDME -5431.0
RPS27A -5429.0
LEAP2 -5413.0
MAP3K1 -5382.0
TRAF2 -5377.0
NFKBIB -5367.0
PECAM1 -5360.0
MAP3K14 -5326.0
DUSP4 -5311.0
KCMF1 -5276.0
CYB5R3 -5227.0
PA2G4 -5207.0
GPI -5199.0
PDAP1 -5190.0
CPN2 -5175.0
CLEC7A -5155.0
EEA1 -5149.0
PSMC1 -5113.0
PLD2 -5102.0
NME2 -5054.0
DEGS1 -5048.0
CD55 -4995.0
PSMB7 -4950.0
TMBIM1 -4893.0
LAIR1 -4890.0
SNAP29 -4858.0
PSAP -4848.0
FUCA2 -4785.0
LCK -4755.0
TP53 -4747.0
SCAMP1 -4722.0
MANBA -4702.0
PSMC4 -4685.0
ATP6V1H -4599.0
MALT1 -4568.0
CAPN1 -4567.0
IRF7 -4529.0
PSMC5 -4488.0
BAIAP2 -4445.0
YES1 -4430.0
DOCK1 -4424.0
ATF2 -4363.0
IQGAP1 -4346.0
PSMA7 -4316.0
IKBKB -4264.0
ABL1 -4263.0
NCKAP1L -4254.0
LAMTOR2 -4242.0
ACTR3 -4236.0
NCK1 -4222.0
FTH1 -4208.0
PAFAH1B2 -4201.0
BRK1 -4189.0
CASP9 -4184.0
TRIM32 -4175.0
ATP6V0E2 -4165.0
CR1 -4159.0
IFNA2 -4144.0
PPIE -4085.0
CD300E -4079.0
CRISPLD2 -4065.0
WIPF2 -4039.0
ALPK1 -4027.0
ALDOA -3954.0
CFB -3904.0
NFKBIA -3895.0
YPEL5 -3885.0
MYO1C -3880.0
PTAFR -3879.0
DUSP7 -3870.0
C6orf120 -3857.0
ABI1 -3800.0
ITPR2 -3785.0
RAB14 -3750.0
MAN2B1 -3697.0
WIPF3 -3692.0
LAMP1 -3691.0
CD47 -3690.0
RASGRP1 -3689.0
XRCC5 -3684.0
ATP6V1G2 -3667.0
HSP90AB1 -3657.0
NKIRAS2 -3624.0
LAT -3609.0
PTGES2 -3602.0
FCN3 -3598.0
C5 -3568.0
TIRAP -3545.0
MAP2K4 -3534.0
SKP1 -3528.0
CDC34 -3441.0
DNAJC3 -3433.0
SARM1 -3384.0
BST2 -3352.0
FYN -3338.0
CYFIP2 -3330.0
AIM2 -3300.0
VAT1 -3298.0
AGA -3283.0
MUC5B -3273.0
DSN1 -3259.0
CLEC4C -3254.0
CPNE1 -3248.0
PSMA8 -3243.0
ARPC2 -3235.0
PIK3C3 -3232.0
RPS6KA2 -3190.0
MAPK9 -3136.0
NFATC1 -3131.0
PSME3 -3093.0
MME -3058.0
C4BPB -3053.0
SLPI -3030.0
GCA -2986.0
MUC16 -2976.0
MVP -2937.0
C4A -2934.5
C4B -2934.5
RAB31 -2896.0
MUC13 -2847.0
UBE2D3 -2833.0
ALDH3B1 -2818.0
STAT6 -2813.0
PTPRJ -2804.0
RAB5B -2791.0
POLR2L -2750.0
CANT1 -2692.0
N4BP1 -2658.0
TMEM30A -2642.0
POLR2E -2608.0
SEMG1 -2601.0
PGLYRP4 -2600.0
BST1 -2575.0
FLG2 -2567.0
PSMD1 -2565.0
PSMD5 -2542.0
RHOF -2506.0
ITPR1 -2499.0
UBA52 -2492.0
PSMA5 -2478.0
FBXW11 -2475.0
PRDX6 -2457.0
ACTG1 -2441.0
CRP -2415.0
FADD -2386.0
MYD88 -2385.0
IQGAP2 -2364.0
CEP290 -2347.0
DDOST -2327.0
DEFB126 -2321.0
CR2 -2301.0
OSCAR -2294.0
PSEN1 -2289.0
EEF2 -2288.0
PSMA4 -2277.0
HSPA6 -2248.0
PTPRN2 -2244.0
DUSP3 -2222.0
CALM1 -2218.0
ZBP1 -2209.0
SNAP25 -2201.0
IRAG2 -2159.0
ABCA13 -2143.0
MAP3K7 -2087.0
IFNA6 -2082.0
RAB24 -2071.0
MAPK7 -2048.0
ORM2 -2043.0
P2RX1 -2029.0
ANO6 -2015.0
TAB2 -2014.0
ROCK1 -1979.0
BPIFA2 -1974.0
UBC -1940.0
SLC27A2 -1909.0
PLAC8 -1846.0
SERPINB6 -1844.0
C1QC -1840.0
PRKCE -1819.0
CLEC12A -1816.0
PPP3CB -1813.0
UNC93B1 -1807.0
HSP90B1 -1787.0
ATP6V1G3 -1735.0
SLC11A1 -1733.0
PKM -1732.0
ELMO2 -1710.0
ATP11B -1586.0
DOK3 -1533.0
CSNK2B -1517.0
CD59 -1495.0
PSME2 -1494.0
CSTB -1478.0
AHSG -1468.0
ORM1 -1424.0
C7 -1408.0
CXCR2 -1396.0
CTSB -1388.0
GPR84 -1352.0
C8A -1346.0
TANK -1247.0
PSMC2 -1220.0
IRF3 -1201.0
PGLYRP3 -1185.0
BTRC -1184.0
MMP9 -1143.0
POLR3E -1112.0
STOM -1107.0
MAPK8 -1052.0
LRRFIP1 -1030.0
MUC1 -1026.0
HEBP2 -1006.0
PPP3CA -986.0
RAF1 -952.0
TNFAIP3 -931.0
LY86 -905.0
NFASC -896.0
MYH9 -874.0
MAVS -864.0
IFNA5 -846.0
CD36 -823.0
PAK1 -791.0
DHX58 -766.0
RPS6KA5 -719.0
PCBP2 -709.0
TAX1BP1 -701.0
RAB3A -698.0
KRAS -603.0
ERP44 -576.0
HLA-E -574.0
CKAP4 -512.0
ITK -487.0
TREM1 -393.0
BCL2 -384.0
DYNC1H1 -361.0
NOS3 -334.0
VAV3 -291.0
LPO -290.0
PRKDC -288.0
HSPA8 -277.0
MAP2K7 -270.0
PSMB1 -252.0
CTNNB1 -251.0
POLR3K -234.0
UBB -227.0
ELMO1 -190.0
PSMD6 -164.0
CNN2 -163.0
GNS -160.0
IRAK3 -118.0
PRCP -78.0
PTK2 -62.0
TMEM63A -23.0
PRKCQ 10.0
COMMD3 60.0
CHRNB4 62.0
DIAPH1 197.0
UBE2D2 201.0
BPIFB1 223.0
CTSA 229.0
MEF2A 237.0
SLC44A2 265.0
ATP6V1F 288.0
MYO10 301.0
ATP11A 321.0
DUSP6 337.0
PTX3 360.0
UBE2K 382.0
TBC1D10C 384.0
IRAK4 414.0
PANX1 447.0
POLR3F 452.0
CAND1 456.0
RAB5C 482.0
IRAK2 488.0
MUC4 537.0
TOM1 611.0
MAP2K6 645.0
APP 650.0
TCIRG1 669.0
RAB10 677.0
CYSTM1 700.0
ARPC3 717.0
DHX36 779.0
PPP3R1 794.0
TLR5 807.0
ATG5 815.0
GYG1 846.0
CTSC 847.0
BIRC2 852.0
CTSS 873.0
CTSV 875.0
PLA2G6 882.0
ITGAV 884.0
CDK13 923.0
DYNLT1 939.0
RAB3D 941.0
IST1 943.0
GDI2 963.0
CCT8 991.0
LIMK1 997.0
MIF 1011.0
HEXB 1019.0
MAPK10 1026.0
SERPINB1 1037.0
NLRP1 1117.0
RAP1B 1146.0
ACTR2 1150.0
LAMTOR1 1185.0
WASF2 1199.0
LCP2 1214.0
LYN 1258.0
PPBP 1287.0
GAB2 1303.0
DYNC1LI1 1352.0
GZMM 1365.0
NFATC3 1376.0
PAK2 1378.0
FGL2 1381.0
PLAUR 1382.0
IFI16 1393.0
ARPC1A 1412.0
NOS1 1446.0
CLEC4D 1452.0
TXNDC5 1461.0
FCGR3A 1480.0
CD53 1501.0
RNASE7 1505.0
ECSIT 1528.0
APOB 1554.0
ATP6V0A4 1648.0
PGM2 1669.0
UBE2N 1694.0
ATP6V1B1 1697.0
MAPK12 1736.0
TMEM179B 1743.0
PLPP4 1750.0
PLCG1 1779.0
PTPN4 1782.0
PSMB4 1792.0
CAPZA1 1811.0
ATF1 1815.0
OSTF1 1852.0
PSMD7 1876.0
FCER1A 1880.0
MS4A3 1906.0
UBE2V1 1909.0
CASP1 1950.0
GHDC 1977.0
DERA 1988.0
VCL 2005.0
MAPKAPK2 2008.0
RAB7A 2021.0
PSMD13 2068.0
PYGB 2184.0
SYK 2191.0
ACLY 2212.0
C5AR2 2217.0
PELI1 2226.0
APRT 2228.0
NFKB1 2237.0
MLEC 2243.0
PIK3CA 2278.0
IGF2R 2291.0
CHUK 2303.0
CREG1 2313.0
LY96 2365.0
HPSE 2373.0
MAPK14 2381.0
C1R 2389.0
NOS2 2391.0
DNAJC13 2393.0
P2RX7 2403.0
PGM1 2442.0
PPP2R5D 2473.0
DEFB135 2489.0
PSMC6 2503.0
NF2 2542.0
PI3 2548.0
GM2A 2557.0
VCP 2571.0
RAB18 2624.0
KRT1 2725.0
GGH 2736.0
PYGL 2764.0
AHCYL1 2773.0
IDH1 2785.0
SEM1 2813.0
SERPING1 2836.0
CFHR5 2838.0
CEACAM1 2876.0
MAP3K8 2905.0
CCT2 2925.0
PPP2R1B 2955.0
TXNIP 2957.0
GALNS 3001.0
GOLGA7 3013.0
PSMB2 3025.0
NLRC3 3037.0
CHGA 3049.0
DNAJC5 3063.0
SVIP 3089.0
CFH 3096.0
PSMB9 3120.0
LGALS3 3124.0
PSMF1 3165.0
CRACR2A 3194.0
RETN 3197.0
COMMD9 3199.0
DSP 3213.0
NFKB2 3228.0
SOCS1 3250.0
PSMD8 3281.0
GRB2 3310.0
TCN1 3340.0
HLA-C 3383.0
PSMD3 3393.0
CTSK 3415.0
ATG12 3426.0
MUC6 3488.0
TRAF6 3503.0
PLD4 3510.0
CD44 3576.0
DEFB113 3583.0
ATP6V1G1 3618.0
PTPRC 3620.0
CDA 3634.0
TOMM70 3669.0
DCD 3688.0
DOCK2 3693.0
PIK3R1 3776.0
PLAU 3777.0
SERPINB12 3814.0
C8G 3837.0
TICAM1 3858.0
FABP5 3903.0
CD81 3921.0
CPPED1 3979.0
DEFA5 3992.0
CFI 4092.0
DEFB118 4106.0
DEFB125 4110.0
BPIFB4 4163.0
FGB 4167.0
HVCN1 4175.0
PSMD9 4183.0
IMPDH1 4184.0
ARSB 4196.0
B2M 4202.0
TXN 4216.0
FGG 4240.0
FCAR 4247.0
FTL 4271.0
CDC42 4288.0
S100A11 4389.0
HSPA1B 4407.0
MASP2 4417.0
LRRC7 4420.0
CD33 4427.0
ADGRE3 4461.0
PSMD14 4464.0
NEU1 4480.0
CAPZA2 4484.0
CLU 4488.0
LILRA3 4501.0
DEFB1 4562.0
TSPAN14 4573.0
SOS1 4593.0
ITGAM 4609.0
EEF1A1 4629.0
SRP14 4631.0
HTN3 4649.0
NCKAP1 4733.0
POLR3C 4754.0
DYNLL1 4803.0
MAP2K1 4867.0
HLA-A 4880.0
UBE2D1 4987.0
MUC3A 4988.0
STBD1 5023.0
ARG1 5030.0
PPP2CA 5054.0
CCR2 5061.0
DHX9 5096.0
FRK 5097.0
WASL 5102.0
ATP6V1A 5106.0
ANXA2 5158.0
BCL2L1 5179.0
HK3 5182.0
VAMP8 5191.0
C1S 5249.0
MGST1 5280.0
PROS1 5305.0
MEF2C 5339.0
FOS 5355.0
CD58 5356.0
C6 5379.0
DEFB110 5436.0
SPTAN1 5469.0
MS4A2 5481.0
CTSH 5536.0
SFTPD 5561.0
SUGT1 5615.0
KPNB1 5625.0
ATP6V1D 5637.0
ITCH 5644.0
CRISP3 5661.0
GSTP1 5685.0
C8B 5688.0
ICAM2 5707.0
AAMP 5711.0
NKIRAS1 5746.0
CUL1 5793.0
KLRK1 5841.0
LYZ 5857.0
S100A7A 5897.0
STING1 5939.0
CFHR4 5965.0
BPIFB6 5984.0
RBSN 6055.0
NCKIPSD 6071.0
ADAM10 6078.0
MBL2 6082.0
PSME1 6143.0
SDCBP 6159.0
ATAD3B 6169.0
PPIA 6172.0
PRKACB 6173.0
HP 6180.0
ENPP4 6209.0
APEH 6267.0
QSOX1 6277.0
PSMB8 6298.0
NRAS 6299.0
ARPC5 6327.0
C3AR1 6366.0
C1QA 6409.0
VAV2 6477.0
DSG1 6486.0
PLA2G2A 6493.0
MMP25 6574.0
UBE2M 6580.0
CFL1 6601.0
C2 6637.0
LRRC14 6693.0
PNP 6705.0
DEFB127 6720.0
JUN 6753.0
IMPDH2 6773.0
DEFB116 6776.0
S100B 6783.0
SAA1 6821.0
BPIFB2 6828.0
SIKE1 6832.0
MNDA 6836.0
PSMC3 6871.0
GRAP2 6881.0
PSMB3 6898.0
POLR3A 6911.0
CD93 6912.0
IFNA8 6945.0
ATOX1 6976.0
TBK1 6986.0
ARL8A 7008.0
MUC17 7109.0
WASF3 7114.0
MASP1 7157.0
CASP4 7159.0
NOD1 7172.0
POLR2H 7187.0
HMOX2 7189.0
CLEC5A 7209.0
MUC15 7249.0
ACTR10 7272.0
POLR3B 7296.0
CD180 7300.0
LILRB2 7316.0
NLRP4 7317.0
GAA 7318.0
CD19 7355.0
DEFB121 7370.0
PSMB6 7376.0
PTPRB 7392.0
HMGB1 7457.0
ADA2 7459.0
DEFB115 7478.0
GMFG 7513.0
RIPK2 7515.0
COLEC10 7531.0
OLFM4 7560.0
SLCO4C1 7569.0
TLR3 7571.0
BIRC3 7655.0
USP14 7708.0
MUCL1 7771.0
DEFB132 7803.0
GUSB 7814.0
ABI2 7876.0
SERPINB10 7878.0
SIRPB1 7881.0
REG3A 7893.0
MYH2 7956.0
CTSL 7969.0
TUBB 7975.0
PRG2 8033.0
XRCC6 8066.0
VAPA 8100.0
C1QB 8138.0
USP18 8153.0
DEFA6 8171.0
PELI3 8194.0
CAT 8250.0
ACP3 8268.0
DEFB124 8354.0
FCGR2A 8403.0
EPX 8506.0
MAPK11 8514.0
IFIH1 8530.0
TTR 8552.0
IFNA13 8579.0
HLA-B 8651.0
OLR1 8703.0
RNASE2 8706.0
A1BG 8726.0
TUBB4B 8798.0
CD68 8808.0
LAMTOR3 8881.0
VNN1 8888.0
POLR3D 8892.0
DEFB114 8918.0
CGAS 8969.0
COPB1 9003.0
ART1 9023.0
DEFB104A 9047.5
DEFB104B 9047.5
S100A12 9057.0
POLR3GL 9083.0
ATP6V0D2 9100.0
DEFB129 9107.0
WASF1 9159.0
RNASE3 9256.0
SFTPA1 9309.0
IFNA1 9314.0
HRNR 9340.0
DEFB119 9361.0
MUC7 9376.0
DSC1 9402.0
DEFB128 9414.0
FOLR3 9428.0
SIGLEC5 9452.0
IFNA16 9463.0
FGA 9466.0
C9 9490.0
CD3G 9544.0
IL1B 9587.0
CLEC6A 9616.0
FPR1 9622.0
CALML5 9674.0
CFHR2 9678.0
HTN1 9771.0
ITLN1 9784.0
IFNA21 9792.0


REACTOME_ELASTIC_FIBRE_FORMATION

REACTOME_ELASTIC_FIBRE_FORMATION
148
set REACTOME_ELASTIC_FIBRE_FORMATION
setSize 44
pANOVA 0.00137
s.dist -0.279
p.adjustANOVA 0.249



Top enriched genes

Top 20 genes
GeneID Gene Rank
FURIN -11356
EMILIN1 -11318
FBLN5 -10530
FBN3 -10273
MFAP4 -10117
VTN -9903
ITGB1 -9802
EFEMP2 -9742
BMP10 -9635
BMP4 -9546
MFAP2 -9400
BMP2 -8976
GDF5 -8723
LOXL1 -7998
LTBP3 -7892
LTBP2 -7232
FBLN2 -7124
LOX -7051
ELN -6851
LOXL2 -6352

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FURIN -11356
EMILIN1 -11318
FBLN5 -10530
FBN3 -10273
MFAP4 -10117
VTN -9903
ITGB1 -9802
EFEMP2 -9742
BMP10 -9635
BMP4 -9546
MFAP2 -9400
BMP2 -8976
GDF5 -8723
LOXL1 -7998
LTBP3 -7892
LTBP2 -7232
FBLN2 -7124
LOX -7051
ELN -6851
LOXL2 -6352
EMILIN3 -5615
TGFB2 -5507
TGFB1 -5470
LOXL3 -5380
FBLN1 -4439
ITGB8 -3966
ITGB5 -2840
EMILIN2 -2693
MFAP3 -2628
MFAP5 -2604
LOXL4 -1913
FBN2 -1485
ITGB6 -480
FN1 348
LTBP1 714
ITGAV 884
BMP7 1218
EFEMP1 1489
LTBP4 1786
ITGA5 3682
FBN1 5779
ITGB3 6829
TGFB3 8479
ITGA8 8692


REACTOME_BETA_DEFENSINS

REACTOME_BETA_DEFENSINS
110
set REACTOME_BETA_DEFENSINS
setSize 27
pANOVA 0.00215
s.dist 0.341
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
DEFB128 9414.0
DEFB119 9361.0
DEFB129 9107.0
DEFB104A 9047.5
DEFB104B 9047.5
DEFB114 8918.0
DEFB124 8354.0
DEFB132 7803.0
DEFB115 7478.0
DEFB121 7370.0
DEFB116 6776.0
DEFB127 6720.0
DEFB110 5436.0
CCR2 5061.0
DEFB1 4562.0
DEFB125 4110.0
DEFB118 4106.0
DEFB113 3583.0
DEFB135 2489.0
DEFB126 -2321.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DEFB128 9414.0
DEFB119 9361.0
DEFB129 9107.0
DEFB104A 9047.5
DEFB104B 9047.5
DEFB114 8918.0
DEFB124 8354.0
DEFB132 7803.0
DEFB115 7478.0
DEFB121 7370.0
DEFB116 6776.0
DEFB127 6720.0
DEFB110 5436.0
CCR2 5061.0
DEFB1 4562.0
DEFB125 4110.0
DEFB118 4106.0
DEFB113 3583.0
DEFB135 2489.0
DEFB126 -2321.0
DEFB134 -6237.0
TLR2 -6469.0
TLR1 -7330.0
DEFB133 -7394.0
DEFB136 -8699.0
CCR6 -8763.0
DEFB123 -11089.0


REACTOME_SIGNALING_BY_NTRKS

REACTOME_SIGNALING_BY_NTRKS
211
set REACTOME_SIGNALING_BY_NTRKS
setSize 132
pANOVA 0.00249
s.dist -0.152
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
FURIN -11356
PPP2CB -11323
DNM1 -11270
PTPN11 -11265
EGR4 -10969
VRK3 -10828
TPH1 -10549
DNM2 -10496
ARC -10409
ID4 -10318
JUND -10302
RAPGEF1 -10226
CDK5R2 -9970
RHOA -9958
RPS6KA1 -9870
RAP1A -9865
PPP2R1A -9863
NAB1 -9836
CLTA -9775
KIDINS220 -9724

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FURIN -11356
PPP2CB -11323
DNM1 -11270
PTPN11 -11265
EGR4 -10969
VRK3 -10828
TPH1 -10549
DNM2 -10496
ARC -10409
ID4 -10318
JUND -10302
RAPGEF1 -10226
CDK5R2 -9970
RHOA -9958
RPS6KA1 -9870
RAP1A -9865
PPP2R1A -9863
NAB1 -9836
CLTA -9775
KIDINS220 -9724
RRAD -9629
MAPK3 -9613
SHC2 -9260
RAC1 -9215
EP300 -9135
MAPKAPK3 -8261
SH3GL2 -8200
SRC -8020
MAPK13 -7904
JUNB -7569
NTRK2 -7506
PCSK5 -7499
DNAL4 -7465
SHC1 -7445
DOCK3 -6984
ID2 -6888
MAPK1 -6855
IRS2 -6743
TRIB1 -6706
MEF2D -6586
CREB1 -6475
RALGDS -6367
YWHAB -6363
CRK -5923
STAT3 -5857
NTF3 -5855
HRAS -5842
ADCYAP1 -5793
PIK3R2 -5785
DNM3 -5716
MAP2K2 -5632
PIK3CB -5554
AP2A2 -5471
DUSP4 -5311
SHC3 -5261
PTPRS -5194
AP2A1 -5033
BAX -5000
SGK1 -4947
CRKL -4451
ATF2 -4363
CHD4 -4361
SH3GL3 -4303
DUSP7 -3870
PTPRO -3792
AP2B1 -3759
FYN -3338
RPS6KA2 -3190
F3 -3023
ADCYAP1R1 -2729
EGR1 -2536
AP2M1 -2424
EGR2 -2414
TIAM1 -2363
DUSP3 -2222
BDNF -2172
ID1 -2139
MAPK7 -2048
LYL1 -1935
GRIN2B -1824
RPS6KA5 -719
KRAS -603
NAB2 -407
NTRK1 -152
NGF -147
BRAF -128
IRS1 156
MEF2A 237
DUSP6 337
GAB1 472
REST 519
ID3 1058
NTRK3 1182
SRF 1196
FRS2 1249
TCF12 1718
MAPK12 1736
PLCG1 1779
ATF1 1815
MAPKAPK2 2008
MAP2K5 2250
PIK3CA 2278
MAPK14 2381
FOSL1 2402
PPP2R5D 2473
PPP2R1B 2955
FOSB 3056
CLTC 3277
CDK5R1 3303
GRB2 3310
RALB 3369
RIT1 3729
PIK3R1 3776
PCSK6 3778
ASCL1 4009
EGR3 4566
SOS1 4593
FRS3 4603
AP2S1 4818
MAP2K1 4867
PPP2CA 5054
MEF2C 5339
FOS 5355
NRAS 6299
VGF 6671
RIT2 7023
NELFB 7211
ADORA2A 7442
CDK5 7549
NTF4 7841
RALA 8296
MAPK11 8514


REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING

REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING
1441
set REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING
setSize 30
pANOVA 0.00255
s.dist -0.318
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATP6V1E2 -11469
ATP6V0C -11115
HFE -10733
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
STEAP3 -10119
ATP6V0A1 -9864
ATP6V1E1 -9547
ATP6V0B -9464
ATP6V1C2 -8680
ATP6V0A2 -8252
TF -7683
ATP6V1C1 -7442
TFR2 -7383
TFRC -6295
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
MCOLN1 -3080

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATP6V1E2 -11469
ATP6V0C -11115
HFE -10733
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
STEAP3 -10119
ATP6V0A1 -9864
ATP6V1E1 -9547
ATP6V0B -9464
ATP6V1C2 -8680
ATP6V0A2 -8252
TF -7683
ATP6V1C1 -7442
TFR2 -7383
TFRC -6295
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
MCOLN1 -3080
ATP6V1G3 -1735
STEAP2 -483
ATP6V1F 288
TCIRG1 669
ATP6V0A4 1648
ATP6V1B1 1697
ATP6V1G1 3618
ATP6V1A 5106
ATP6V1D 5637
ATP6V0D2 9100


REACTOME_GLUCURONIDATION

REACTOME_GLUCURONIDATION
146
set REACTOME_GLUCURONIDATION
setSize 23
pANOVA 0.00283
s.dist 0.36
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
UGT2B7 9321
UGT2B11 9149
UGT2B4 8860
UGT1A1 7905
UGT2A1 7263
UGT1A4 6875
UGT1A3 6667
UGT1A5 5973
UGT2A2 5460
UGT1A8 4361
UGT1A10 4284
UGT3A1 3842
SLC35D1 3592
UGT1A9 2869
ABHD10 2690
UGT1A7 2362
UGT1A6 1838
UGT2A3 -1637
UGT3A2 -2226
UGP2 -3924

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UGT2B7 9321
UGT2B11 9149
UGT2B4 8860
UGT1A1 7905
UGT2A1 7263
UGT1A4 6875
UGT1A3 6667
UGT1A5 5973
UGT2A2 5460
UGT1A8 4361
UGT1A10 4284
UGT3A1 3842
SLC35D1 3592
UGT1A9 2869
ABHD10 2690
UGT1A7 2362
UGT1A6 1838
UGT2A3 -1637
UGT3A2 -2226
UGP2 -3924
UGT2B17 -5879
UGT2B15 -6262
UGDH -8677


REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX
1419
set REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX
setSize 36
pANOVA 0.00292
s.dist -0.287
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
APOC2 -11825
APOC1 -11616
APOC4 -11175
NR1H3 -10493
NCOR2 -9383
EP300 -9135
ABCG5 -9096
RXRB -9089
AGO4 -9083
KDM4A -8535
ABCG8 -7280
TBL1XR1 -7172
AGO3 -6734
KDM3A -6666
AGO2 -6437
TNRC6B -6276
MOV10 -6234
EEPD1 -5753
RXRA -4727
ABCG1 -4581

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
APOC2 -11825
APOC1 -11616
APOC4 -11175
NR1H3 -10493
NCOR2 -9383
EP300 -9135
ABCG5 -9096
RXRB -9089
AGO4 -9083
KDM4A -8535
ABCG8 -7280
TBL1XR1 -7172
AGO3 -6734
KDM3A -6666
AGO2 -6437
TNRC6B -6276
MOV10 -6234
EEPD1 -5753
RXRA -4727
ABCG1 -4581
TNRC6C -4153
APOE -3458
AGO1 -3242
NCOR1 -2952
CETP -1821
NR1H2 -1019
TNRC6A -478
KDM1A -169
HDAC3 859
GPS2 1247
KDM1B 1503
NCOA1 1808
APOD 3293
PLTP 3818
ABCA1 4451
ARL4C 7228


REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
973
set REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
setSize 418
pANOVA 0.00323
s.dist -0.084
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
PSMB11 -11786
DKK1 -11558
AXIN1 -11389
RAC2 -11337
PPP2CB -11323
PTPN11 -11265
PDGFB -11261
CNKSR1 -11159
BIN2 -11074
NOTCH1 -11055
TPM4 -10938
MIB2 -10758
SMAD3 -10719
AGTRAP -10714
SYVN1 -10698
PSMB10 -10684
CD28 -10634
ARRB1 -10624
FZD8 -10551
KREMEN2 -9945

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PSMB11 -11786
DKK1 -11558
AXIN1 -11389
RAC2 -11337
PPP2CB -11323
PTPN11 -11265
PDGFB -11261
CNKSR1 -11159
BIN2 -11074
NOTCH1 -11055
TPM4 -10938
MIB2 -10758
SMAD3 -10719
AGTRAP -10714
SYVN1 -10698
PSMB10 -10684
CD28 -10634
ARRB1 -10624
FZD8 -10551
KREMEN2 -9945
RAP1A -9865
PPP2R1A -9863
PSMD2 -9860
MAP3K11 -9840
PSMD4 -9796
FGF17 -9795
EEF1G -9778
FIP1L1 -9690
HDAC10 -9658
MAPK3 -9613
PSENEN -9539
ACTB -9512
EREG -9459
NCOR2 -9383
CEP43 -9342
MPRIP -9274
GCC2 -9226
RAC1 -9215
EP300 -9135
HEY1 -9122
FKBP1A -9119
PDPK1 -9058
POLR2F -9035
BCR -8969
CPSF6 -8847
FGFR1 -8809
PRKAR1A -8804
PIK3CD -8794
PSMB5 -8682
MRAS -8543
PDGFRB -8453
ATG7 -8373
NCSTN -8358
MYO18A -8350
SQSTM1 -8309
TRAT1 -8251
NPM1 -8228
BRAP -8205
ARRB2 -8137
DUSP10 -8113
CSK -8088
HDAC11 -8080
APH1B -8075
SRC -8020
FAM114A2 -7962
CAMK2B -7960
HSP90AA1 -7947
PTPN12 -7938
DKK2 -7897
FZD6 -7866
CAMK2A -7857
ADAM17 -7843
FGF3 -7761
POLR2K -7746
PSMA3 -7677
IHH -7608
JUNB -7569
PSMD11 -7547
ERBB2 -7536
CTBP1 -7530
PSME4 -7486
SHC1 -7445
AKT1 -7424
RHOG -7357
TBL1XR1 -7172
KAT2B -7153
VAV1 -7135
POLR2I -7076
ETV6 -7046
BCL2A1 -7022
PSMA2 -6980
RPS6KB2 -6943
PSMA1 -6876
ZC3HC1 -6864
MAPK1 -6855
AKT1S1 -6845
CBL -6836
KREMEN1 -6821
FGF10 -6816
TGFBR2 -6786
JAG1 -6760
IRS2 -6743
TLN1 -6730
PAPSS1 -6651
RNF43 -6549
KANK1 -6520
PIK3AP1 -6487
ZMYM2 -6485
PEBP1 -6481
CREB1 -6475
RBX1 -6402
PSMA6 -6365
YWHAB -6363
TENT4A -6347
POLR2B -6193
ZC3HAV1 -6188
MLST8 -6015
PSMD12 -5986
TRIP11 -5888
STAT3 -5857
ERLEC1 -5848
HRAS -5842
KSR1 -5836
PIK3R2 -5785
ATIC -5774
AGK -5636
MAP2K2 -5632
CREBBP -5580
STRN -5579
PIK3CB -5554
TGFB1 -5470
SEC31A -5438
RPS27A -5429
FGF4 -5425
JAG2 -5396
SPTBN1 -5366
MDM2 -5358
HEYL -5337
MET -5303
PSMC1 -5113
FOXO1 -5027
SHH -5017
PSMB7 -4950
LCK -4755
PTEN -4735
PPP1CC -4710
PSMC4 -4685
BCL11A -4683
CTBP2 -4674
SEL1L -4512
FGFR4 -4506
PSMC5 -4488
FGF5 -4466
YES1 -4430
HDAC4 -4420
PDGFRA -4391
TGFA -4364
IQGAP1 -4346
MAML1 -4336
PSMA7 -4316
VWF -4293
DLL4 -4276
CASP9 -4184
PIM1 -4139
CDKN1B -4124
STAT5A -4080
CAMK2G -4058
TRIM24 -4018
POLR2C -3908
DUSP7 -3870
CSNK1A1 -3863
SND1 -3816
CDC37 -3781
AKAP9 -3585
SKP1 -3528
HBEGF -3512
FGF7 -3477
PPP2R5E -3396
CARS1 -3388
KDM7A -3386
FYN -3338
HDAC5 -3323
PSMA8 -3243
APC -3237
MTOR -3141
SPRED3 -3121
CDKN1A -3108
PSME3 -3093
KIT -3011
NCOR1 -2952
EGFR -2951
SNW1 -2890
RRBP1 -2883
GOLGB1 -2874
CUX1 -2859
GSK3A -2845
POLR2L -2750
SMAD2 -2703
POLR2E -2608
PSMD1 -2565
CDK8 -2549
PSMD5 -2542
TPM3 -2516
HDAC7 -2498
UBA52 -2492
PSMA5 -2478
ACTG1 -2441
LRP6 -2410
BCL2L11 -2398
TNKS2 -2320
ITGA2B -2315
PSEN1 -2289
PSMA4 -2277
FGF22 -2272
CALM1 -2218
EPGN -2182
SHOC2 -2148
TFG -2132
NR4A1 -2078
ERBB3 -2070
AKT3 -2061
DCTN1 -2036
PHB1 -1994
CLCN6 -1943
UBC -1940
DHH -1744
AP3B1 -1724
FXR1 -1652
EGF -1565
PSME2 -1494
BAG4 -1402
ALK -1343
NEURL1B -1266
PSMC2 -1220
APH1A -1132
PPFIBP1 -1130
LRRFIP1 -1030
LRP5 -1012
HIP1 -999
APBB1IP -957
RAF1 -952
NRG3 -936
MYH9 -874
NCBP2 -821
CAMK2D -669
PPP2R5C -615
KRAS -603
MIB1 -586
TCF7L2 -567
DERL2 -521
FGF9 -390
CD80 -371
PSMB1 -252
CTNNB1 -251
CCNC -239
UBB -227
WNT3A -166
PSMD6 -164
BRAF -128
DUSP16 124
SMAD4 153
IRS1 156
FOXO3 270
NEURL1 313
TSC2 315
DUSP6 337
FN1 348
ERBB4 376
GTF2F2 441
GAB1 472
TNKS 492
FZD4 507
KDR 632
ZFYVE9 655
RNF213 695
KIF5B 760
FGF19 818
RBPJ 836
HDAC3 859
MYC 885
POLR2G 905
MAML3 962
EML4 1070
PIK3R3 1089
SPRED1 1144
RAP1B 1146
BAD 1176
POLR2A 1181
FRS2 1249
FBXW7 1252
LYN 1258
GAB2 1303
HDAC2 1402
FGFR2 1468
KLC1 1491
KIAA1549 1510
QKI 1562
GSK3B 1624
PRR5 1693
PLCG1 1779
TRAK1 1785
PSMB4 1792
PSEN2 1872
PSMD7 1876
ICOS 1896
GOLGA4 1914
VCL 2005
PSMD13 2068
PDGFA 2106
LMNA 2155
PIK3CA 2278
CHUK 2303
PPP2R5D 2473
NRG2 2475
HDAC9 2480
FLT3LG 2499
PSMC6 2503
DLL1 2547
FGFR1OP2 2549
VCP 2571
AKT2 2580
FGF2 2607
BIRC6 2677
MAML2 2695
RPS6 2710
FGF8 2782
STAT5B 2810
SEM1 2813
HDAC1 2892
PPP2R1B 2955
PSMB2 3025
RICTOR 3052
PSMB9 3120
TPR 3148
PSMF1 3165
NCBP1 3239
CLTC 3277
PSMD8 3281
GRB2 3310
DUSP8 3332
PSMD3 3393
CEBPB 3407
NRG1 3428
HEY2 3559
NF1 3703
FGF18 3732
EIF2AK3 3736
ESR2 3743
POLR2J 3759
PIK3R1 3776
MARK3 3799
KITLG 3828
HES1 3838
FGF23 4002
PPM1B 4032
GTF2F1 4043
HHAT 4060
PPP2R5B 4085
LMO7 4136
FGB 4167
PPP2R5A 4180
PSMD9 4183
FGG 4240
PSMD14 4464
RANBP2 4543
ERLIN2 4581
SOS1 4593
FRS3 4603
FGF6 4713
ESRP1 4745
CD86 4756
MAP2K1 4867
FGF1 4877
BTC 4915
STAT1 5051
PPP2CA 5054
FGFR3 5146
BCL2L1 5179
PPP1CB 5222
ESR1 5312
NRG4 5345
WDCP 5482
WDR48 5654
CUL1 5793
FZD5 5802
KSR2 5970
CNTRL 6010
AGGF1 6059
ADAM10 6078
FGF20 6132
KAT2A 6138
PSME1 6143
FOXO6 6263
PSMB8 6298
NRAS 6299
MAPKAP1 6313
KL 6654
FAM131B 6806
ITGB3 6829
PSMC3 6871
PSMB3 6898
FLT3 6941
SPRED2 7040
JAK2 7072
POLR2H 7187
CD19 7355
PSMB6 7376
HES5 7473
TGFBR1 7517
OS9 7566
AREG 7784
POLR2D 8061
NOX4 8172
HGF 8325
ERBIN 8546
KLB 8790
DKK4 9399
FGA 9466


REACTOME_SIGNALING_BY_GPCR

REACTOME_SIGNALING_BY_GPCR
593
set REACTOME_SIGNALING_BY_GPCR
setSize 673
pANOVA 0.00324
s.dist -0.0666
p.adjustANOVA 0.332



Top enriched genes

Top 20 genes
GeneID Gene Rank
TAS2R39 -12134
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
TAS1R3 -11995
GRK2 -11978
UCN2 -11952
GHRH -11891
C5AR1 -11866
ADCY7 -11853
LTB4R -11826
CCL1 -11821
UCN -11817
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TAS2R39 -12134
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
TAS1R3 -11995
GRK2 -11978
UCN2 -11952
GHRH -11891
C5AR1 -11866
ADCY7 -11853
LTB4R -11826
CCL1 -11821
UCN -11817
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690
PRLHR -11657
CCL22 -11631
SCT -11592
CCL20 -11562
PLPPR3 -11533
CCL27 -11529
PPP1CA -11495
CCL21 -11489
PRLH -11475
NPBWR2 -11472
GNG11 -11464
CCL17 -11359
F2RL3 -11350
PREX1 -11341
PRKACA -11338
PPP2CB -11323
GPR32 -11299
CCL5 -11216
NPFF -11062
GNG3 -10992
NTSR1 -10955
TAS2R8 -10933
HCAR1 -10882
HTR1A -10864
PTGDR2 -10835
CCL25 -10815
GPBAR1 -10798
QRFP -10790
AVPR1B -10777
ADCY4 -10769
RLN3 -10750
GNAI2 -10681
ADRB3 -10679
PMCH -10662
ARRB1 -10624
MLN -10613
EDN2 -10602
RGS19 -10601
EDN1 -10553
FZD8 -10551
GPR83 -10520
AGT -10501
ARHGEF39 -10425
ARHGEF33 -10308
CMKLR1 -10301
FPR2 -10297
TAS2R30 -10267
ARHGEF2 -10264
CHRM4 -10260
GPR183 -10235
PDE4A -10217
MC2R -10167
PTH2R -10137
RAMP3 -10103
S1PR2 -10029
CAMKK2 -10012
CRHBP -10010
RGS11 -9971
GALR2 -9968
RHOA -9958
DRD1 -9918
ADORA2B -9910
RPS6KA1 -9870
PPP2R1A -9863
CCL16 -9832
HTR1B -9824
SSTR3 -9823
NMB -9814
ITGB1 -9802
P2RY2 -9712
HTR5A -9709
VIP -9695
MAPK3 -9613
CCL2 -9572
GNB1 -9556
RASGRP2 -9507
ADCY1 -9465
PRKCD -9415
HRH3 -9382
GALR1 -9378
RAMP2 -9334
TBXA2R -9290
ARHGEF16 -9284
TAS1R2 -9220
ADGRE2 -9169
SMO -9082
GALR3 -9062
PDPK1 -9058
PTGDR -9051
CXCL12 -9046
TRHR -9009
P2RY11 -9006
PDE4C -8992
UTS2B -8942
ADRA1D -8903
GNAI3 -8894
DGKZ -8865
NMUR2 -8845
MC1R -8833
PRKAR1A -8804
FZD10 -8791
S1PR3 -8769
CCR6 -8763
P2RY1 -8754
CCRL2 -8698
CXCL9 -8684
PLCB3 -8653
C3 -8646
ARHGEF4 -8622
CHRM1 -8606
DRD5 -8587
DAGLB -8584
F2RL2 -8434
NTSR2 -8395
ECE2 -8374
GNAS -8327
CXCL1 -8270
HRH2 -8156
ARRB2 -8137
WNT9B -8070
TAS2R20 -8066
NMU -8039
SRC -8020
NPY -8006
GPER1 -7976
CAMK2B -7960
GPR25 -7907
DGKD -7883
CALCA -7870
FZD6 -7866
CAMK2A -7857
PRKCH -7814
XCL2 -7765
TAS2R14 -7755
PPP1R1B -7716
GPR37L1 -7701
RGS18 -7698
GNG5 -7692
GRK6 -7622
IHH -7608
GNAT1 -7599
CAMKK1 -7555
EDNRB -7524
CXCL10 -7516
SHC1 -7445
AKT1 -7424
GNG4 -7396
MC5R -7373
ADGRE5 -7300
XCL1 -7299
PIK3R5 -7226
POMC -7216
RHOC -7208
TAS2R5 -7198
NMBR -7158
CXCR1 -7149
ARHGEF18 -7147
VAV1 -7135
CCR9 -7125
DGKG -7093
RGS4 -7078
PDE1B -7071
CCL3 -7010
OXTR -7003
WNT5A -6950
F2 -6935
MAPK1 -6855
GNRH2 -6828
PNOC -6815
GNG10 -6722
PRKACG -6681
TAC1 -6659
ADM -6647
GPR35 -6575
PTH2 -6552
GPR150 -6530
PDE2A -6525
CREB1 -6475
NPFFR1 -6454
GAL -6440
GPR20 -6427
PROK2 -6373
WNT10A -6369
KISS1R -6294
PROKR1 -6256
LPAR1 -6212
CXCR6 -6210
PLEKHG2 -6199
PLCB1 -6110
GNA15 -6105
NPBWR1 -6088
GNGT2 -6044
TAAR5 -6041
P2RY12 -6019
ITPR3 -6012
PTCH2 -5963
HRAS -5842
ADCYAP1 -5793
PIK3R2 -5785
PLPPR4 -5784
OPRL1 -5782
PDE3B -5658
ARHGEF1 -5612
GPR132 -5601
ADRB1 -5589
LPAR2 -5585
BDKRB2 -5581
CXCL3 -5574
OPN1SW -5563
NPY2R -5527
PRKAR2A -5493
PLEKHG5 -5484
WNT9A -5481
S1PR4 -5446
NPY1R -5436
SCTR -5422
CXCL16 -5320
F2R -5315
CCR7 -5215
WNT7B -5154
HCRT -5142
TRH -5141
GRM6 -5112
DAGLA -5109
PF4 -5097
CCK -5072
SHH -5017
CXCL8 -5015
GNB5 -5001
CD55 -4995
GNAQ -4962
GNG2 -4850
PSAP -4848
SSTR2 -4815
GHSR -4783
ACKR2 -4750
APLNR -4704
MGLL -4627
PDE3A -4614
PLPPR2 -4570
AGTR1 -4507
GPRC6A -4448
ARHGEF37 -4435
PLPPR1 -4410
FFAR4 -4399
GRK3 -4331
PTH1R -4329
GNAT2 -4235
ARHGEF25 -4193
GNG7 -4167
GNAI1 -4123
LPAR5 -4104
ADCY5 -4086
CAMK2G -4058
ADORA3 -4048
PPY -4028
PRKCG -3996
LPAR3 -3977
TSHR -3938
KEL -3896
PTAFR -3879
PTCH1 -3828
SSTR5 -3820
CXCL5 -3819
ITPR2 -3785
ARHGEF10L -3770
GPSM1 -3746
KNG1 -3701
PYY -3696
RASGRP1 -3689
RXFP2 -3654
HTR2A -3620
RAMP1 -3588
C5 -3568
GNAL -3536
HBEGF -3512
RGSL1 -3359
CHRM2 -3311
CXCL2 -3269
DRD3 -3247
RPS6KA2 -3190
CCR10 -3158
CCL23 -3102
RGS10 -3052
GPHB5 -3033
CASR -2999
ARHGEF15 -2985
PIK3R6 -2969
NGEF -2963
EGFR -2951
GPR55 -2806
GRM2 -2766
ECE1 -2747
ADCYAP1R1 -2729
PRKAR2B -2679
GABBR2 -2677
RGS13 -2640
KISS1 -2619
GRM4 -2612
RGS9 -2599
ITPR1 -2499
DGKH -2491
ARHGEF19 -2392
TIAM1 -2363
GABBR1 -2299
CALM1 -2218
CALCB -2213
CXCL11 -2171
EDN3 -2169
FZD9 -2166
DRD2 -2145
MCHR2 -2106
ADCY3 -2066
CRH -2064
AKT3 -2061
MAPK7 -2048
NET1 -2009
TAS1R1 -1999
S1PR1 -1998
PTGFR -1993
ROCK1 -1979
ARHGEF17 -1966
TIAM2 -1868
PRKCE -1819
PPP3CB -1813
ARHGEF3 -1792
DHH -1744
PDE4D -1730
RGS17 -1649
MTNR1B -1568
ADRA1A -1547
CGA -1451
CXCR2 -1396
GRP -1392
GPR84 -1352
PDE8A -1313
ROCK2 -1309
ADM2 -1274
SST -1272
ADRA2A -1225
P2RY6 -1176
WNT8A -1175
AVPR1A -1147
ARHGEF10 -1069
PPP3CA -986
TACR2 -974
WNT4 -972
TRPC6 -899
GPR176 -897
GNB4 -853
PAK1 -791
ADCY2 -724
ARHGEF12 -710
CAMK2D -669
GHRL -634
GLP2R -618
KRAS -603
AKAP13 -594
FGD4 -535
RGS5 -488
OPRK1 -463
RGS16 -395
GPR68 -394
ADRB2 -309
VAV3 -291
ADORA1 -261
MTNR1A -198
WNT3A -166
NPSR1 -142
HTR1D -121
GPR39 -94
HTR4 -92
PLPPR5 -59
GHRHR -56
GRM8 -15
PRKCQ 10
WNT6 155
CCKBR 157
OXER1 166
ADRA1B 184
MCF2L 195
P2RY14 218
ECT2 228
TAS2R4 247
CCL13 294
FN1 348
WNT2B 364
GRM1 371
TRPC3 445
WNT3 476
ABHD12 478
ARHGEF40 498
FZD4 507
HRH1 509
TACR3 542
GNAZ 555
GPR17 621
KPNA2 646
APP 650
NMS 733
VIPR1 777
OPN5 783
MCHR1 785
PPP3R1 794
RHO 795
TAS2R50 822
WNT10B 850
CHRM3 864
CXCR4 937
FZD3 968
PTGER1 1036
RGS12 1051
PIK3R3 1089
TAS2R38 1092
CX3CL1 1134
QRFPR 1286
PPBP 1287
PLA2G4A 1299
ABR 1349
RGS14 1353
ARHGEF26 1368
ADRA2B 1409
RASGRF2 1522
PROKR2 1536
FZD7 1595
GPSM3 1633
HCRTR1 1663
SSTR1 1682
RHOB 1683
CYSLTR2 1727
HTR2B 1775
GPR27 1855
RGS8 1858
TAS2R3 1859
ARHGEF7 1910
GPR15 1913
PDE7B 1958
GCG 1972
WNT11 1975
TACR1 1984
TRPC7 2025
PENK 2034
GNAT3 2081
PLXNB1 2097
FGD3 2112
MC4R 2121
ADCY9 2128
RGS6 2142
C5AR2 2217
WNT8B 2252
PIK3CA 2278
WNT7A 2306
FFAR3 2328
PPP2R5D 2473
MMP3 2498
CALCRL 2569
AKT2 2580
MC3R 2635
TAS2R10 2681
ADCY6 2694
AHCYL1 2773
GNB3 2797
GNB2 2815
INSL3 2827
ADGRE1 2850
ITSN1 2914
CNR1 2916
PPP2R1B 2955
PRKCB 3010
PDE1C 3022
NTS 3035
DGKA 3095
PRKAR1B 3155
RXFP3 3180
F2RL1 3211
GRK5 3255
CRHR1 3268
GRB2 3310
VIPR2 3342
FZD2 3344
TAS2R9 3352
PRKCA 3430
GNG8 3600
HTR6 3621
EDNRA 3638
MLNR 3642
GAST 3651
ITGA5 3682
HTR7 3706
PDYN 3744
RGS2 3760
PIK3R1 3776
RGS22 3830
GNA12 3835
SOS2 3884
OBSCN 3918
ARHGEF38 3926
CORT 4004
GIPR 4013
PDE11A 4047
TRIO 4066
CXCL6 4122
TAAR2 4155
PDE8B 4158
HCRTR2 4223
CDC42 4288
RGS7 4303
FSHB 4327
PDE10A 4332
GLP1R 4333
ANXA1 4428
GNA11 4432
NPY5R 4456
ADGRE3 4461
PDE4B 4462
GNA13 4532
SOS1 4593
PLCB4 4666
NPW 4681
ADCY8 4687
HTR1F 4758
DGKQ 4759
WNT16 4831
PTGER4 4850
TAS2R46 4886
DRD4 4922
CCR5 4925
FZD1 4935
S1PR5 4961
DGKE 4966
PPP2CA 5054
NPFFR2 5060
CCR2 5061
HEBP1 5104
CCL7 5153
HRH4 5163
WNT2 5247
TAAR8 5336
GPR45 5419
ABHD6 5452
NLN 5474
GRM3 5493
TAS2R31 5495
PTGER2 5496
CALCR 5510
GPHA2 5572
GRM7 5586
PLCB2 5627
GRM5 5692
CAMK4 5722
FZD5 5802
RXFP1 5826
LPAR6 5845
LHCGR 5924
CCR4 5988
PCP2 5995
BDKRB1 6068
ACKR1 6100
GNRHR 6127
XCR1 6142
GPR31 6153
PDE1A 6157
PRKACB 6173
RGS3 6226
OPRM1 6259
TAS2R60 6273
GPR18 6276
NRAS 6299
C3AR1 6366
SSTR4 6374
TAAR1 6378
OXGR1 6395
RGR 6397
GPR37 6420
VAV2 6477
GNRH1 6488
PTHLH 6499
TAC3 6521
TAS2R13 6543
TSHB 6627
FGD2 6689
HTR1E 6735
TAS2R19 6736
RGS20 6789
CCR3 6817
GNG12 6818
SAA1 6821
OPN3 6889
KALRN 6951
ACKR4 6953
ARHGEF11 6970
LHB 7079
FFAR1 7175
UTS2R 7218
PROK1 7248
DGKI 7254
ACKR3 7281
CCKAR 7287
CRHR2 7332
INSL5 7358
GPSM2 7390
PDE7A 7398
P2RY13 7413
ADORA2A 7442
OPN4 7449
FSHR 7455
FPR3 7458
PPP3CC 7502
PIK3CG 7520
CDK5 7549
FFAR2 7591
GNA14 7595
NBEA 7725
DGKB 7822
TAS2R41 7845
TAS2R1 7846
UTS2 7913
GIP 7953
NPS 7990
CCR8 7991
CNR2 8077
TAAR9 8164
TAAR6 8169
CCL11 8186
GNG13 8304
HCAR2 8332
CHRM5 8344
GPR65 8385
PTGER3 8401
TAS2R16 8406
WNT1 8425
RGS1 8460
OPRD1 8483
CXCL13 8489
TAS2R7 8520
CCL28 8578
TAS2R40 8629
UCN3 8766
ADRA2C 8833
IAPP 8834
PTH 8903
TAS2R42 8907
TAS2R43 8953
RRH 8991
CCR1 9046
RGS21 9152
NPB 9157
GNGT1 9233
OXT 9243
PTGIR 9270
RLN2 9437
FPR1 9622
ARHGEF5 9673


REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES

REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
615
set REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES
setSize 55
pANOVA 0.00385
s.dist -0.225
p.adjustANOVA 0.372



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CXCR5 -12019
CCL1 -11821
CX3CR1 -11710
CCL22 -11631
CCL20 -11562
CCL27 -11529
CCL21 -11489
CCL17 -11359
CCL5 -11216
CCL25 -10815
CCL16 -9832
CCL2 -9572
CXCL12 -9046
CCR6 -8763
CCRL2 -8698
CXCL9 -8684
CXCL1 -8270
XCL2 -7765

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CXCR5 -12019
CCL1 -11821
CX3CR1 -11710
CCL22 -11631
CCL20 -11562
CCL27 -11529
CCL21 -11489
CCL17 -11359
CCL5 -11216
CCL25 -10815
CCL16 -9832
CCL2 -9572
CXCL12 -9046
CCR6 -8763
CCRL2 -8698
CXCL9 -8684
CXCL1 -8270
XCL2 -7765
CXCL10 -7516
XCL1 -7299
CXCR1 -7149
CCR9 -7125
CCL3 -7010
CXCR6 -6210
CXCL3 -5574
CXCL16 -5320
CCR7 -5215
PF4 -5097
CXCL8 -5015
ACKR2 -4750
CXCL5 -3819
CXCL2 -3269
CCR10 -3158
CXCL11 -2171
CXCR2 -1396
CCL13 294
CXCR4 937
CX3CL1 1134
PPBP 1287
CXCL6 4122
CCR5 4925
CCR2 5061
CCL7 5153
CCR4 5988
XCR1 6142
CCR3 6817
ACKR4 6953
ACKR3 7281
CCR8 7991
CCL11 8186
CXCL13 8489
CCL28 8578
CCR1 9046


REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
594
set REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize 312
pANOVA 0.00416
s.dist -0.0943
p.adjustANOVA 0.379



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
C5AR1 -11866
LTB4R -11826
CCL1 -11821
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690
PRLHR -11657
CCL22 -11631
CCL20 -11562
PLPPR3 -11533
CCL27 -11529
CCL21 -11489
PRLH -11475

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
C5AR1 -11866
LTB4R -11826
CCL1 -11821
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690
PRLHR -11657
CCL22 -11631
CCL20 -11562
PLPPR3 -11533
CCL27 -11529
CCL21 -11489
PRLH -11475
NPBWR2 -11472
CCL17 -11359
F2RL3 -11350
CCL5 -11216
NPFF -11062
NTSR1 -10955
HCAR1 -10882
HTR1A -10864
PTGDR2 -10835
CCL25 -10815
GPBAR1 -10798
QRFP -10790
AVPR1B -10777
RLN3 -10750
ADRB3 -10679
PMCH -10662
MLN -10613
EDN2 -10602
EDN1 -10553
AGT -10501
CMKLR1 -10301
FPR2 -10297
CHRM4 -10260
GPR183 -10235
MC2R -10167
S1PR2 -10029
GALR2 -9968
DRD1 -9918
ADORA2B -9910
CCL16 -9832
HTR1B -9824
SSTR3 -9823
NMB -9814
P2RY2 -9712
HTR5A -9709
CCL2 -9572
HRH3 -9382
GALR1 -9378
TBXA2R -9290
GALR3 -9062
PTGDR -9051
CXCL12 -9046
TRHR -9009
P2RY11 -9006
UTS2B -8942
ADRA1D -8903
NMUR2 -8845
MC1R -8833
S1PR3 -8769
CCR6 -8763
P2RY1 -8754
CCRL2 -8698
CXCL9 -8684
C3 -8646
CHRM1 -8606
DRD5 -8587
F2RL2 -8434
NTSR2 -8395
ECE2 -8374
CXCL1 -8270
HRH2 -8156
NMU -8039
NPY -8006
GPER1 -7976
XCL2 -7765
GPR37L1 -7701
EDNRB -7524
CXCL10 -7516
MC5R -7373
XCL1 -7299
POMC -7216
NMBR -7158
CXCR1 -7149
CCR9 -7125
CCL3 -7010
OXTR -7003
F2 -6935
GNRH2 -6828
PNOC -6815
TAC1 -6659
GPR35 -6575
NPFFR1 -6454
GAL -6440
PROK2 -6373
KISS1R -6294
PROKR1 -6256
LPAR1 -6212
CXCR6 -6210
NPBWR1 -6088
TAAR5 -6041
P2RY12 -6019
PLPPR4 -5784
OPRL1 -5782
GPR132 -5601
ADRB1 -5589
LPAR2 -5585
BDKRB2 -5581
CXCL3 -5574
OPN1SW -5563
NPY2R -5527
S1PR4 -5446
NPY1R -5436
CXCL16 -5320
F2R -5315
CCR7 -5215
HCRT -5142
TRH -5141
PF4 -5097
CCK -5072
CXCL8 -5015
PSAP -4848
SSTR2 -4815
GHSR -4783
ACKR2 -4750
APLNR -4704
PLPPR2 -4570
AGTR1 -4507
PLPPR1 -4410
FFAR4 -4399
LPAR5 -4104
ADORA3 -4048
PPY -4028
LPAR3 -3977
TSHR -3938
KEL -3896
PTAFR -3879
SSTR5 -3820
CXCL5 -3819
KNG1 -3701
PYY -3696
RXFP2 -3654
HTR2A -3620
C5 -3568
CHRM2 -3311
CXCL2 -3269
DRD3 -3247
CCR10 -3158
CCL23 -3102
GPHB5 -3033
GPR55 -2806
ECE1 -2747
KISS1 -2619
CXCL11 -2171
EDN3 -2169
DRD2 -2145
MCHR2 -2106
S1PR1 -1998
PTGFR -1993
MTNR1B -1568
ADRA1A -1547
CGA -1451
CXCR2 -1396
GRP -1392
SST -1272
ADRA2A -1225
P2RY6 -1176
AVPR1A -1147
TACR2 -974
GHRL -634
OPRK1 -463
GPR68 -394
ADRB2 -309
ADORA1 -261
MTNR1A -198
NPSR1 -142
HTR1D -121
GPR39 -94
HTR4 -92
PLPPR5 -59
CCKBR 157
OXER1 166
ADRA1B 184
P2RY14 218
CCL13 294
HRH1 509
TACR3 542
GPR17 621
APP 650
NMS 733
OPN5 783
MCHR1 785
RHO 795
CHRM3 864
CXCR4 937
PTGER1 1036
CX3CL1 1134
QRFPR 1286
PPBP 1287
ADRA2B 1409
PROKR2 1536
HCRTR1 1663
SSTR1 1682
CYSLTR2 1727
HTR2B 1775
TACR1 1984
PENK 2034
MC4R 2121
C5AR2 2217
FFAR3 2328
MC3R 2635
INSL3 2827
CNR1 2916
NTS 3035
RXFP3 3180
F2RL1 3211
HTR6 3621
EDNRA 3638
MLNR 3642
HTR7 3706
PDYN 3744
CORT 4004
CXCL6 4122
TAAR2 4155
HCRTR2 4223
FSHB 4327
ANXA1 4428
NPY5R 4456
NPW 4681
HTR1F 4758
PTGER4 4850
DRD4 4922
CCR5 4925
S1PR5 4961
NPFFR2 5060
CCR2 5061
HEBP1 5104
CCL7 5153
HRH4 5163
TAAR8 5336
NLN 5474
PTGER2 5496
GPHA2 5572
RXFP1 5826
LPAR6 5845
LHCGR 5924
CCR4 5988
BDKRB1 6068
ACKR1 6100
GNRHR 6127
XCR1 6142
GPR31 6153
OPRM1 6259
GPR18 6276
C3AR1 6366
SSTR4 6374
TAAR1 6378
OXGR1 6395
RGR 6397
GPR37 6420
GNRH1 6488
TAC3 6521
TSHB 6627
HTR1E 6735
CCR3 6817
SAA1 6821
OPN3 6889
ACKR4 6953
LHB 7079
FFAR1 7175
UTS2R 7218
PROK1 7248
ACKR3 7281
CCKAR 7287
INSL5 7358
P2RY13 7413
ADORA2A 7442
OPN4 7449
FSHR 7455
FPR3 7458
FFAR2 7591
UTS2 7913
NPS 7990
CCR8 7991
CNR2 8077
TAAR9 8164
TAAR6 8169
CCL11 8186
HCAR2 8332
CHRM5 8344
GPR65 8385
PTGER3 8401
OPRD1 8483
CXCL13 8489
CCL28 8578
ADRA2C 8833
RRH 8991
CCR1 9046
NPB 9157
OXT 9243
PTGIR 9270
RLN2 9437
FPR1 9622


REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION
1518
set REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION
setSize 74
pANOVA 0.00527
s.dist -0.188
p.adjustANOVA 0.456



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
FURIN -11356
PRKACA -11338
DPEP2 -11042
GNG3 -10992
ADCY4 -10769
GNAI2 -10681
CD247 -10495
ADORA2B -9910
GNB1 -9556
ADCY1 -9465
DPEP1 -9396
GNAI3 -8894
PRKAR1A -8804
GNAS -8327
SRC -8020
ADAM17 -7843
GNG5 -7692
FGR -7507

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
FURIN -11356
PRKACA -11338
DPEP2 -11042
GNG3 -10992
ADCY4 -10769
GNAI2 -10681
CD247 -10495
ADORA2B -9910
GNB1 -9556
ADCY1 -9465
DPEP1 -9396
GNAI3 -8894
PRKAR1A -8804
GNAS -8327
SRC -8020
ADAM17 -7843
GNG5 -7692
FGR -7507
GNG4 -7396
RHBDF2 -7322
CD163 -7180
GNG10 -6722
PRKACG -6681
DPEP3 -6585
CREB1 -6475
GGT1 -6273
HCK -6054
GNGT2 -6044
ITPR3 -6012
PLCG2 -5798
PRKAR2A -5493
GNB5 -5001
GNG2 -4850
PLK2 -4808
YES1 -4430
GNG7 -4167
GNAI1 -4123
ADCY5 -4086
ITPR2 -3785
GGT5 -3453
FYN -3338
PRKAR2B -2679
ITPR1 -2499
CALM1 -2218
ADCY3 -2066
MYH9 -874
GNB4 -853
ADCY2 -724
GNAZ 555
IL6 738
LYN 1258
FCGR3A 1480
CYSLTR2 1727
PLCG1 1779
GNAT3 2081
ADCY9 2128
SYK 2191
MAPK14 2381
ADCY6 2694
AHCYL1 2773
GNB3 2797
GNB2 2815
PRKAR1B 3155
GNG8 3600
ADCY8 4687
PRKACB 6173
GNG12 6818
GNG13 8304
FCGR2A 8403
GNGT1 9233
IL10 9516
CD3G 9544


REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING

REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING
839
set REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING
setSize 45
pANOVA 0.00584
s.dist -0.237
p.adjustANOVA 0.458



Top enriched genes

Top 20 genes
GeneID Gene Rank
CSF2 -11982
IL2 -11868
IL2RB -11759
IL3 -11646
PRKACA -11338
PTPN11 -11265
RAPGEF1 -10226
JAK1 -10086
INPP5D -9904
CSF2RB -9664
PIK3CD -8794
PTPN6 -7453
SHC1 -7445
VAV1 -7135
TEC -7088
CBL -6836
JAK3 -6576
IL5 -6517
HCK -6054
CRK -5923

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CSF2 -11982
IL2 -11868
IL2RB -11759
IL3 -11646
PRKACA -11338
PTPN11 -11265
RAPGEF1 -10226
JAK1 -10086
INPP5D -9904
CSF2RB -9664
PIK3CD -8794
PTPN6 -7453
SHC1 -7445
VAV1 -7135
TEC -7088
CBL -6836
JAK3 -6576
IL5 -6517
HCK -6054
CRK -5923
PIK3R2 -5785
PIK3CB -5554
RPS27A -5429
CRKL -4451
YES1 -4430
STAT5A -4080
FYN -3338
INPPL1 -2996
UBA52 -2492
UBC -1940
UBB -227
PIK3R3 1089
LYN 1258
GAB2 1303
SYK 2191
PIK3CA 2278
STAT5B 2810
BLNK 3179
GRB2 3310
PIK3R1 3776
SOS1 4593
YWHAZ 4708
IL2RA 5396
JAK2 7072
IL5RA 8675


REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES
443
set REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES
setSize 37
pANOVA 0.00586
s.dist -0.262
p.adjustANOVA 0.458



Top enriched genes

Top 20 genes
GeneID Gene Rank
EMILIN1 -11318
FBLN5 -10530
FBN3 -10273
MFAP4 -10117
VTN -9903
ITGB1 -9802
EFEMP2 -9742
BMP10 -9635
BMP4 -9546
MFAP2 -9400
BMP2 -8976
GDF5 -8723
LTBP3 -7892
LTBP2 -7232
FBLN2 -7124
ELN -6851
EMILIN3 -5615
TGFB2 -5507
TGFB1 -5470
FBLN1 -4439

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
EMILIN1 -11318
FBLN5 -10530
FBN3 -10273
MFAP4 -10117
VTN -9903
ITGB1 -9802
EFEMP2 -9742
BMP10 -9635
BMP4 -9546
MFAP2 -9400
BMP2 -8976
GDF5 -8723
LTBP3 -7892
LTBP2 -7232
FBLN2 -7124
ELN -6851
EMILIN3 -5615
TGFB2 -5507
TGFB1 -5470
FBLN1 -4439
ITGB8 -3966
ITGB5 -2840
EMILIN2 -2693
MFAP3 -2628
MFAP5 -2604
FBN2 -1485
ITGB6 -480
FN1 348
LTBP1 714
ITGAV 884
BMP7 1218
EFEMP1 1489
LTBP4 1786
FBN1 5779
ITGB3 6829
TGFB3 8479
ITGA8 8692


REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG

REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG
123
set REACTOME_ACYL_CHAIN_REMODELING_OF_DAG_AND_TAG
setSize 5
pANOVA 0.00637
s.dist -0.704
p.adjustANOVA 0.476



Top enriched genes

Top 20 genes
GeneID Gene Rank
PNPLA2 -11636
DGAT2 -10859
DGAT1 -10797
PNPLA3 -6527
MGLL -4627

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PNPLA2 -11636
DGAT2 -10859
DGAT1 -10797
PNPLA3 -6527
MGLL -4627


REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES

REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
480
set REACTOME_CONDENSATION_OF_PROPHASE_CHROMOSOMES
setSize 66
pANOVA 0.00697
s.dist 0.192
p.adjustANOVA 0.498



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
RB1 7193.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
RB1 7193.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0
H3-3A 5167.0
CDK1 4928.0
H4C12 4671.0
SMC4 4599.0
NCAPD3 4499.0
H2BC11 4341.0
NCAPH2 3914.0
PLK1 3740.0
H3C4 3221.0
H4C3 2803.0
H2AC7 2726.5
H2BC7 2726.5
CCNB1 2565.0
H3-4 1612.0
H2BC12 1426.0
SMC2 788.0
H2BC5 741.0
H4C16 326.0
H2BC9 -18.5
H3C7 -18.5
H4C9 -77.0
H2AZ1 -219.0
H3C8 -1195.0
H2BC4 -1847.0
H2AC6 -2387.0
MCPH1 -2526.0
H3C2 -3371.0
H2BC26 -3442.0
H2BC1 -4333.0
H4C13 -4551.0
NCAPG2 -4673.0
H2AC8 -5188.0
H4C11 -5525.0
H2BC13 -5652.0
H3-3B -6496.0
H3C11 -6664.0
SET -7346.0
H2AC20 -8295.0
H2BC21 -8370.0
H2BC10 -8462.0
H3C10 -8504.0
H2AJ -8875.0
H4C2 -9517.0
H2BC8 -9562.0
H2BC15 -9905.0
KMT5A -11143.0


REACTOME_TRANSPORT_OF_SMALL_MOLECULES

REACTOME_TRANSPORT_OF_SMALL_MOLECULES
630
set REACTOME_TRANSPORT_OF_SMALL_MOLECULES
setSize 697
pANOVA 0.00789
s.dist -0.059
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
PIP -12115
AVP -12023
P4HB -11939
SLC5A2 -11903
ADCY7 -11853
APOC2 -11825
PSMB11 -11786
SGK2 -11741
ZDHHC8 -11706
AQP6 -11685
CLCN1 -11671
APOC1 -11616
AQP8 -11476
ATP6V1E2 -11469
GNG11 -11464
LCN15 -11424
ANGPTL8 -11409
FURIN -11356
AQP5 -11346
ATP8B4 -11345

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PIP -12115.0
AVP -12023.0
P4HB -11939.0
SLC5A2 -11903.0
ADCY7 -11853.0
APOC2 -11825.0
PSMB11 -11786.0
SGK2 -11741.0
ZDHHC8 -11706.0
AQP6 -11685.0
CLCN1 -11671.0
APOC1 -11616.0
AQP8 -11476.0
ATP6V1E2 -11469.0
GNG11 -11464.0
LCN15 -11424.0
ANGPTL8 -11409.0
FURIN -11356.0
AQP5 -11346.0
ATP8B4 -11345.0
PRKACA -11338.0
SLC16A3 -11263.0
SLC15A4 -11209.0
APOC4 -11175.0
ATP6V0C -11115.0
SLC46A1 -11107.0
SLC2A3 -11095.0
SLCO4A1 -11076.0
GNG3 -10992.0
SLC22A16 -10980.0
APOA4 -10916.0
WNK4 -10851.0
AQP3 -10845.0
SLC50A1 -10839.0
TRPM2 -10804.0
HBB -10802.0
ADCY4 -10769.0
HFE -10733.0
ATP6V1B2 -10690.0
PSMB10 -10684.0
SLC24A3 -10668.0
NR1H3 -10493.0
SLC2A6 -10490.0
SLC26A6 -10469.0
AQP12A -10418.5
SLC39A1 -10414.0
SLC2A8 -10386.0
SLC12A3 -10284.0
ATP6V0E1 -10257.0
ABCC11 -10238.0
VLDLR -10237.0
ATP9A -10206.0
BEST2 -10203.0
ATP6V0D1 -10139.0
STEAP3 -10119.0
SLC13A2 -10043.0
LCN9 -10008.0
SLC35D2 -9907.0
ATP6V0A1 -9864.0
PSMD2 -9860.0
LETM1 -9849.0
VDAC2 -9843.0
CA2 -9820.0
PSMD4 -9796.0
CLTA -9775.0
CLCNKA -9774.0
LRRC8A -9765.0
CYGB -9756.0
SLC22A11 -9737.0
SLC4A3 -9707.0
FTMT -9670.0
SLC9A3 -9651.0
ABCB6 -9632.0
ABCA2 -9598.0
ABCA6 -9595.0
BEST4 -9568.0
GNB1 -9556.0
ATP6V1E1 -9547.0
SCARB1 -9487.0
APOA5 -9474.0
ADCY1 -9465.0
ATP6V0B -9464.0
TRPV4 -9414.0
TRPV5 -9370.0
PEX19 -9367.0
SLC39A7 -9327.0
SLC6A18 -9307.0
SLC4A7 -9240.0
SCNN1A -9237.0
SLC24A1 -9233.0
SLCO2B1 -9203.0
CYB5R1 -9106.0
LCAT -9101.0
ABCG5 -9096.0
ABCC10 -9081.0
SLC45A3 -9047.0
NIPA1 -9040.0
LPL -8991.0
SLC35B2 -8980.0
APOBR -8923.0
SOAT2 -8915.0
SLC24A4 -8901.0
TTYH2 -8892.0
FXYD4 -8825.0
SLC38A3 -8812.0
PRKAR1A -8804.0
MB -8790.0
ASIC4 -8733.0
PSMB5 -8682.0
ATP6V1C2 -8680.0
SLC43A2 -8663.0
ATP8B1 -8604.0
NPC2 -8588.0
ABCB8 -8518.0
SLC35B4 -8475.0
GPIHBP1 -8426.0
LCN2 -8386.0
DMTN -8372.0
GNAS -8327.0
SLC7A10 -8304.0
CYBRD1 -8292.0
SLC9A1 -8279.0
ATP6V0A2 -8252.0
RNF5 -8183.0
RIPK3 -8122.0
MIP -8118.0
SLC39A4 -8074.0
SLC22A4 -8050.0
SLC5A11 -8047.0
SLC35C1 -8022.0
ATP2B4 -7971.0
SLC6A7 -7961.0
CAMK2B -7960.0
RIPK1 -7931.0
SLC27A1 -7926.0
LMF2 -7886.0
UNC80 -7879.0
CAMK2A -7857.0
SLC12A4 -7815.0
ATP2A3 -7795.0
APOF -7784.0
GNG5 -7692.0
TF -7683.0
PSMA3 -7677.0
ABCC3 -7575.0
SLC9A8 -7557.0
PSMD11 -7547.0
SLC8B1 -7515.0
PCSK5 -7499.0
PSME4 -7486.0
ATP6V1C1 -7442.0
ATP12A -7407.0
GNG4 -7396.0
TFR2 -7383.0
SLC43A1 -7361.0
ABCG8 -7280.0
ATP4A -7275.0
AQP4 -7267.0
SLC2A2 -7222.0
ABCC2 -7212.0
SLC9A4 -7192.0
SLC17A7 -7184.0
SLC39A2 -7167.0
SLC6A9 -7143.0
SLC8A2 -7137.0
TPCN2 -7132.0
ABCA4 -7103.0
SCNN1B -7074.0
PSMA2 -6980.0
ABCC6 -6965.0
SLC25A10 -6963.0
SLC35B3 -6922.0
ANO10 -6893.0
PSMA1 -6876.0
STOML2 -6801.0
SLC28A3 -6795.0
ATP1A4 -6783.0
SLC39A5 -6740.0
LIPA -6723.0
GNG10 -6722.0
SLC2A4 -6711.0
SLC13A5 -6685.0
PRKACG -6681.0
CYB5RL -6676.0
ABCG4 -6665.0
ATP8A1 -6656.0
SLC25A4 -6639.0
ANO8 -6545.0
SLC16A1 -6370.0
PSMA6 -6365.0
SLC7A6 -6316.0
TFRC -6295.0
HDLBP -6268.0
BEST1 -6232.0
SLC1A4 -6198.0
SLC38A4 -6169.0
SLC5A3 -6158.0
OSTM1 -6154.0
SLC36A1 -6137.0
CASQ1 -6127.0
AQP9 -6078.0
ATP1B3 -6058.0
GNGT2 -6044.0
TRPC1 -6013.0
PSMD12 -5986.0
CLCNKB -5961.0
ATP4B -5920.0
ERLEC1 -5848.0
LRRC8D -5832.0
NIPAL4 -5760.0
SLC6A13 -5711.0
SLC9A5 -5708.0
TRPV3 -5694.0
AHCYL2 -5621.0
CSN3 -5590.0
SLC2A14 -5570.0
HMOX1 -5508.0
ARL2 -5498.0
PRKAR2A -5493.0
ATP1A2 -5476.0
AP2A2 -5471.0
RPS27A -5429.0
ARL2BP -5421.0
SLC7A2 -5342.0
CA4 -5299.0
SCNN1D -5246.0
MTTP -5162.0
PSMC1 -5113.0
ADD1 -5106.0
SLC9B1 -5093.0
SLC29A1 -5092.0
SLC34A1 -5037.0
AP2A1 -5033.0
GNB5 -5001.0
PSMB7 -4950.0
SGK1 -4947.0
RNF185 -4943.0
SLC44A4 -4933.0
NIPAL1 -4857.0
GNG2 -4850.0
SLC3A1 -4837.0
ABCC1 -4831.0
SLC5A10 -4816.0
CTNS -4803.0
SLC9A2 -4713.0
PSMC4 -4685.0
SLC13A3 -4653.0
SLC30A3 -4623.0
ATP6V1H -4599.0
ABCG1 -4581.0
SLC18A1 -4571.0
DERL1 -4516.0
ANO2 -4515.0
SEL1L -4512.0
PARL -4501.0
PSMC5 -4488.0
SLC14A1 -4428.0
SLC13A4 -4414.0
SLC2A7 -4412.0
SLC30A10 -4324.0
PSMA7 -4316.0
SLC3A2 -4297.0
ANO7 -4279.0
SMDT1 -4237.0
SLC5A6 -4219.0
FTH1 -4208.0
MYO5B -4168.0
GNG7 -4167.0
ATP6V0E2 -4165.0
SLC30A2 -4116.0
ADCY5 -4086.0
SLC8A1 -4066.0
CAMK2G -4058.0
ABCB4 -4017.0
ABCC4 -4008.0
NEDD4L -3978.0
CREB3L3 -3953.0
LDLRAP1 -3921.0
AFG3L2 -3898.0
LDLR -3854.0
AP2B1 -3759.0
RSC1A1 -3722.0
ERLIN1 -3714.0
ATP6V1G2 -3667.0
SLC16A10 -3647.0
SLC6A1 -3608.0
SLC6A19 -3575.0
SKP1 -3528.0
NIPAL2 -3520.0
SLC12A5 -3463.0
APOE -3458.0
SLC18A2 -3373.0
ANGPTL3 -3368.0
SLC30A1 -3276.0
SLC17A8 -3264.0
PSMA8 -3243.0
SLCO2A1 -3230.0
SLC5A12 -3172.0
SLC7A5 -3171.0
NIPAL3 -3143.0
ABCA9 -3122.0
SLC27A6 -3100.0
ATP1B1 -3095.0
PSME3 -3093.0
MCOLN1 -3080.0
ATP10D -3050.0
SLC22A5 -3035.0
ATP1B2 -3034.0
ATP2B2 -2938.0
KCNJ11 -2925.0
SLC28A1 -2904.0
DERL3 -2898.0
LIPG -2776.0
SLC1A3 -2774.0
BEST3 -2728.0
SLCO3A1 -2697.0
FXYD7 -2696.0
SLC5A7 -2684.0
PRKAR2B -2679.0
TTYH1 -2662.0
SLC9C1 -2636.0
PSMD1 -2565.0
PSMD5 -2542.0
ATP8A2 -2533.0
UBA52 -2492.0
ATP10A -2487.0
EMB -2480.0
PSMA5 -2478.0
SLC29A4 -2445.0
AP2M1 -2424.0
TRPM5 -2298.0
PSMA4 -2277.0
SLC26A11 -2224.0
CALM1 -2218.0
ATP2A1 -2190.0
WNK2 -2173.0
SLC29A2 -2141.0
SLC8A3 -2136.0
SLC32A1 -2096.0
SLC2A12 -2074.0
ADCY3 -2066.0
ANO6 -2015.0
PHB1 -1994.0
AKAP1 -1978.0
CLCN6 -1943.0
UBC -1940.0
IREB2 -1853.0
ABCA7 -1834.0
CETP -1821.0
CLCN7 -1799.0
SLC2A10 -1771.0
TRPM6 -1755.0
SLC22A12 -1745.0
ATP6V1G3 -1735.0
SLC11A1 -1733.0
ATP13A2 -1705.0
ANGPTL4 -1680.0
SLC44A1 -1653.0
ABCF1 -1639.0
CUTC -1624.0
RHCG -1605.0
ATP11B -1586.0
RUNX1 -1577.0
FXYD6 -1560.0
SLC5A8 -1554.0
SLC6A11 -1534.0
SLC1A2 -1519.0
PSME2 -1494.0
MRS2 -1374.0
SLC20A2 -1249.0
PSMC2 -1220.0
SLC14A2 -1190.0
SLC5A5 -1163.0
SLC24A2 -1154.0
STOM -1107.0
VDAC1 -1087.0
ANO1 -1076.0
SLC5A1 -1047.0
NR1H2 -1019.0
SLC15A1 -998.0
RAF1 -952.0
RYR2 -926.0
TRPC6 -899.0
SLC6A2 -895.0
NPC1 -890.0
GNB4 -853.0
SLC47A2 -811.0
SLC2A1 -781.0
ANO4 -755.0
ATP1A1 -730.0
ADCY2 -724.0
CAMK2D -669.0
FLVCR1 -665.0
ACO1 -626.0
SLC4A9 -620.0
SLC1A7 -605.0
ABCA3 -597.0
RYR1 -595.0
SLC26A1 -584.0
ASPH -568.0
DERL2 -521.0
RHBG -502.0
STEAP2 -483.0
SOAT1 -435.0
SLC47A1 -415.0
SLC39A3 -364.0
VDAC3 -342.0
MCOLN2 -298.0
ATP8B3 -275.0
CA1 -263.0
ABCB9 -262.0
PSMB1 -252.0
SLC22A1 -249.0
ANKH -237.0
UBB -227.0
AQP2 -185.0
CUBN -179.0
PSMD6 -164.0
TTYH3 -126.0
TRPC4 -90.0
SLC6A6 -63.0
MICU1 -45.0
RAB11A -30.0
SLC25A29 6.0
NIPA2 91.0
SLC16A8 109.0
SGK3 154.0
RHAG 248.0
SAR1B 262.0
SLC44A2 265.0
ATP6V1F 288.0
ATP11A 321.0
SLC9B2 409.0
TRPC3 445.0
CAND1 456.0
SLC20A1 473.0
SLC6A3 521.0
SLC33A1 536.0
TRPC4AP 651.0
ABCA8 659.0
TCIRG1 669.0
ABCB1 739.0
SLC66A1 746.0
SLC1A1 757.0
SLC34A2 865.0
SLC34A3 920.0
CP 958.0
SLC24A5 995.0
HBA1 1017.0
ATP2B1 1055.0
SLC1A5 1056.0
LRRC8B 1087.0
ASIC2 1103.0
ATP10B 1179.0
SLC11A2 1231.0
SLC6A12 1265.0
LRRC8C 1266.0
SLC41A1 1301.0
SCNN1G 1302.0
LRRC8E 1305.0
SLC13A1 1309.0
SLC4A2 1327.0
SLC2A11 1332.0
SLC26A7 1345.0
SLC6A15 1362.0
TRPV2 1477.0
SLC41A2 1482.0
RAB11FIP2 1493.0
SLC39A10 1514.0
SLC15A3 1517.0
APOB 1554.0
CLCN2 1580.0
SLC36A4 1591.0
ADD2 1604.0
NGB 1637.0
ATP6V0A4 1648.0
NALCN 1662.0
ATP6V1B1 1697.0
PSMB4 1792.0
MAIP1 1793.0
CLCA2 1806.0
SLC22A18 1810.0
MCUB 1827.0
PLN 1839.0
CES3 1842.0
SLC39A8 1861.0
LIPC 1867.0
PSMD7 1876.0
SLC12A6 1889.0
SLC6A20 1970.0
SLC35A3 1990.0
TRPC7 2025.0
PSMD13 2068.0
SLC5A4 2102.0
ADCY9 2128.0
CYB5R2 2247.0
BSG 2309.0
TRPM3 2350.0
TPCN1 2364.0
NEDD8 2384.0
PEX3 2461.0
PSMC6 2503.0
SPG7 2513.0
FKBP1B 2546.0
SLC38A1 2558.0
VCP 2571.0
LSR 2692.0
ADCY6 2694.0
ASIC3 2745.0
SLC12A2 2747.0
GNB3 2797.0
SEM1 2813.0
GNB2 2815.0
ALB 2817.0
SLC25A22 2994.0
TUSC3 3002.0
PSMB2 3025.0
LMF1 3077.0
SLC22A3 3100.0
PSMB9 3120.0
MICU2 3134.0
PRKAR1B 3155.0
PSMF1 3165.0
TRPM8 3170.0
SLC29A3 3183.0
AQP1 3195.0
CLTC 3277.0
PSMD8 3281.0
APOD 3293.0
PSMD3 3393.0
SLC7A11 3440.0
LCN12 3523.0
WWP1 3534.0
SLC39A14 3542.0
ANO9 3575.0
SLC35D1 3592.0
GNG8 3600.0
ATP6V1G1 3618.0
SLC2A9 3658.0
ATP8B2 3665.0
ATP2A2 3674.0
SLC22A17 3691.0
CYB5R4 3711.0
SLN 3748.0
GLRX3 3761.0
SLC35A1 3769.0
TRPV6 3771.0
PCSK6 3778.0
PLTP 3818.0
SLC7A7 3866.0
NCEH1 3890.0
SLC7A1 4026.0
SLC17A1 4042.0
ATP2C2 4095.0
ATP9B 4125.0
SLC22A15 4141.0
ABCB5 4164.0
SLC4A4 4168.0
PSMD9 4183.0
SLC15A2 4187.0
TRPM1 4254.0
AQP7 4267.0
FTL 4271.0
SLC27A4 4281.0
SLC26A2 4406.0
ABCA1 4451.0
SRI 4460.0
PSMD14 4464.0
ADD3 4477.0
PMPCA 4526.0
LPA 4547.0
ERLIN2 4581.0
ABCD3 4598.0
PMPCB 4651.0
RYR3 4652.0
ADCY8 4687.0
AP2S1 4818.0
CLCA4 4841.0
YME1L1 4855.0
BMP1 4929.0
SLC7A8 5015.0
SLC4A1 5020.0
SLC26A3 5025.0
ATP6V1A 5106.0
SLC16A7 5115.0
MYLIP 5223.0
ANO5 5226.0
UNC79 5240.0
TRPM4 5281.0
ABCG2 5285.0
CASQ2 5318.0
SLC6A5 5406.0
SLC17A6 5428.0
SLC25A18 5432.0
ABCC9 5433.0
SLC26A9 5491.0
FXYD1 5494.0
ABCA12 5511.0
ATP13A4 5570.0
ATP13A1 5583.0
SLC2A13 5622.0
ATP6V1D 5637.0
FXYD2 5645.0
CFTR 5664.0
APOA1 5670.0
PHB2 5678.0
WNK1 5710.0
ATP2C1 5715.0
CUL1 5793.0
SLC39A6 5865.0
CLCN3 5866.0
PCSK9 5895.0
ABCA10 5899.0
ANO3 5920.0
SLC44A5 5946.0
SLC4A5 5959.0
SLC38A2 6116.0
PSME1 6143.0
SLC25A26 6144.0
PRKACB 6173.0
SLC9A9 6193.0
MCOLN3 6199.0
SLC4A8 6272.0
LCN1 6289.0
PSMB8 6298.0
SLC22A2 6314.0
TRDN 6319.0
MBTPS1 6320.0
ASIC1 6346.0
AQP11 6398.0
SLC44A3 6507.0
FGF21 6651.0
A2M 6725.0
ABCC5 6754.0
SLC22A8 6763.0
SLC26A4 6803.0
GNG12 6818.0
ATP1A3 6860.0
PSMC3 6871.0
SLC22A6 6894.0
PSMB3 6898.0
SLC17A5 6903.0
SLC12A1 6933.0
STOML3 6991.0
SLCO1B1 7092.0
ABCA5 7171.0
EIF2S1 7180.0
MCU 7183.0
HMOX2 7189.0
TRPV1 7195.0
SLC4A10 7214.0
SLC12A7 7216.0
ATP7B 7246.0
SLC36A2 7258.0
PSMB6 7376.0
ATP13A5 7381.0
MLKL 7396.0
CIDEC 7406.0
OS9 7566.0
SLCO4C1 7569.0
SLCO1A2 7603.0
APOA2 7616.0
TRPA1 7621.0
SLC17A3 7625.0
SLC9C2 7764.0
AZGP1 7847.0
AQP10 7865.0
BSND 7879.0
SLC5A9 7931.0
SLCO1B3 7984.0
TRPM7 8042.0
SLC31A1 8126.0
SLC30A5 8145.0
HBA2 8196.0
EIF2S2 8259.0
GNG13 8304.0
SLC40A1 8307.0
ASIC5 8317.0
AMN 8366.0
APOC3 8381.0
MFSD4B 8428.0
SLC1A6 8503.0
FXYD3 8604.0
SLC22A7 8616.0
SLC30A8 8695.0
ABCB10 8748.0
SLC28A2 8760.0
SLC7A9 8799.0
CLCA1 8817.0
MICU3 8886.0
SLCO1C1 8895.0
FBXL5 9017.0
CSN1S1 9040.0
ABCD2 9056.0
SLC10A6 9094.0
ATP6V0D2 9100.0
GNGT1 9233.0


REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY

REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY
65
set REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY
setSize 11
pANOVA 0.00817
s.dist 0.461
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
HLA-F 9053
HLA-B 8651
CTSL 7969
HLA-A 4880
B2M 4202
HLA-C 3383
HLA-G 2147
LNPEP 1713
CTSV 875
CTSS 873
HLA-E -574

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HLA-F 9053
HLA-B 8651
CTSL 7969
HLA-A 4880
B2M 4202
HLA-C 3383
HLA-G 2147
LNPEP 1713
CTSV 875
CTSS 873
HLA-E -574


REACTOME_INTERLEUKIN_10_SIGNALING

REACTOME_INTERLEUKIN_10_SIGNALING
1039
set REACTOME_INTERLEUKIN_10_SIGNALING
setSize 43
pANOVA 0.00927
s.dist -0.229
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CSF2 -11982
CCL22 -11631
CCL20 -11562
FCER2 -11330
CCL5 -11216
LIF -11067
TNFRSF1B -10604
JAK1 -10086
CCL2 -9572
CSF3 -9485
PTGS2 -8943
IL10RB -8366
ICAM1 -8361
CXCL1 -8270
CXCL10 -7516
CCL3 -7010
TYK2 -6710
IL1A -6115

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CSF2 -11982
CCL22 -11631
CCL20 -11562
FCER2 -11330
CCL5 -11216
LIF -11067
TNFRSF1B -10604
JAK1 -10086
CCL2 -9572
CSF3 -9485
PTGS2 -8943
IL10RB -8366
ICAM1 -8361
CXCL1 -8270
CXCL10 -7516
CCL3 -7010
TYK2 -6710
IL1A -6115
STAT3 -5857
CXCL8 -5015
TNFRSF1A -4881
IL1R2 -4408
TNF -4077
PTAFR -3879
CXCL2 -3269
IL1R1 -2452
CD80 -371
IL1RN 644
IL6 738
IL12A 1254
IL10RA 1392
IL18 4237
CSF1 4725
CD86 4756
CCR5 4925
CCR2 5061
IL12B 5429
CCR1 9046
IL10 9516
IL1B 9587
FPR1 9622


REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING
834
set REACTOME_GPCR_LIGAND_BINDING
setSize 444
pANOVA 0.00958
s.dist -0.0717
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
TAS2R39 -12134
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
TAS1R3 -11995
UCN2 -11952
GHRH -11891
C5AR1 -11866
LTB4R -11826
CCL1 -11821
UCN -11817
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690
PRLHR -11657
CCL22 -11631

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TAS2R39 -12134
CCL4 -12111
CCL19 -12088
AVP -12023
CXCR5 -12019
LTB4R2 -12011
TAS1R3 -11995
UCN2 -11952
GHRH -11891
C5AR1 -11866
LTB4R -11826
CCL1 -11821
UCN -11817
GPR4 -11774
RXFP4 -11770
CX3CR1 -11710
NMUR1 -11707
SUCNR1 -11690
PRLHR -11657
CCL22 -11631
SCT -11592
CCL20 -11562
PLPPR3 -11533
CCL27 -11529
CCL21 -11489
PRLH -11475
NPBWR2 -11472
GNG11 -11464
CCL17 -11359
F2RL3 -11350
CCL5 -11216
NPFF -11062
GNG3 -10992
NTSR1 -10955
TAS2R8 -10933
HCAR1 -10882
HTR1A -10864
PTGDR2 -10835
CCL25 -10815
GPBAR1 -10798
QRFP -10790
AVPR1B -10777
RLN3 -10750
ADRB3 -10679
PMCH -10662
MLN -10613
EDN2 -10602
EDN1 -10553
FZD8 -10551
AGT -10501
CMKLR1 -10301
FPR2 -10297
TAS2R30 -10267
CHRM4 -10260
GPR183 -10235
MC2R -10167
PTH2R -10137
RAMP3 -10103
S1PR2 -10029
CRHBP -10010
GALR2 -9968
DRD1 -9918
ADORA2B -9910
CCL16 -9832
HTR1B -9824
SSTR3 -9823
NMB -9814
P2RY2 -9712
HTR5A -9709
VIP -9695
CCL2 -9572
GNB1 -9556
HRH3 -9382
GALR1 -9378
RAMP2 -9334
TBXA2R -9290
TAS1R2 -9220
ADGRE2 -9169
SMO -9082
GALR3 -9062
PTGDR -9051
CXCL12 -9046
TRHR -9009
P2RY11 -9006
UTS2B -8942
ADRA1D -8903
NMUR2 -8845
MC1R -8833
FZD10 -8791
S1PR3 -8769
CCR6 -8763
P2RY1 -8754
CCRL2 -8698
CXCL9 -8684
C3 -8646
CHRM1 -8606
DRD5 -8587
F2RL2 -8434
NTSR2 -8395
ECE2 -8374
GNAS -8327
CXCL1 -8270
HRH2 -8156
WNT9B -8070
TAS2R20 -8066
NMU -8039
NPY -8006
GPER1 -7976
CALCA -7870
FZD6 -7866
XCL2 -7765
TAS2R14 -7755
GPR37L1 -7701
GNG5 -7692
IHH -7608
EDNRB -7524
CXCL10 -7516
GNG4 -7396
MC5R -7373
ADGRE5 -7300
XCL1 -7299
POMC -7216
TAS2R5 -7198
NMBR -7158
CXCR1 -7149
CCR9 -7125
CCL3 -7010
OXTR -7003
WNT5A -6950
F2 -6935
GNRH2 -6828
PNOC -6815
GNG10 -6722
TAC1 -6659
ADM -6647
GPR35 -6575
PTH2 -6552
NPFFR1 -6454
GAL -6440
PROK2 -6373
WNT10A -6369
KISS1R -6294
PROKR1 -6256
LPAR1 -6212
CXCR6 -6210
NPBWR1 -6088
GNGT2 -6044
TAAR5 -6041
P2RY12 -6019
PTCH2 -5963
ADCYAP1 -5793
PLPPR4 -5784
OPRL1 -5782
GPR132 -5601
ADRB1 -5589
LPAR2 -5585
BDKRB2 -5581
CXCL3 -5574
OPN1SW -5563
NPY2R -5527
WNT9A -5481
S1PR4 -5446
NPY1R -5436
SCTR -5422
CXCL16 -5320
F2R -5315
CCR7 -5215
WNT7B -5154
HCRT -5142
TRH -5141
GRM6 -5112
PF4 -5097
CCK -5072
SHH -5017
CXCL8 -5015
GNB5 -5001
CD55 -4995
GNG2 -4850
PSAP -4848
SSTR2 -4815
GHSR -4783
ACKR2 -4750
APLNR -4704
PLPPR2 -4570
AGTR1 -4507
GPRC6A -4448
PLPPR1 -4410
FFAR4 -4399
PTH1R -4329
GNG7 -4167
LPAR5 -4104
ADORA3 -4048
PPY -4028
LPAR3 -3977
TSHR -3938
KEL -3896
PTAFR -3879
PTCH1 -3828
SSTR5 -3820
CXCL5 -3819
KNG1 -3701
PYY -3696
RXFP2 -3654
HTR2A -3620
RAMP1 -3588
C5 -3568
CHRM2 -3311
CXCL2 -3269
DRD3 -3247
CCR10 -3158
CCL23 -3102
GPHB5 -3033
CASR -2999
GPR55 -2806
GRM2 -2766
ECE1 -2747
ADCYAP1R1 -2729
GABBR2 -2677
KISS1 -2619
GRM4 -2612
GABBR1 -2299
CALCB -2213
CXCL11 -2171
EDN3 -2169
FZD9 -2166
DRD2 -2145
MCHR2 -2106
CRH -2064
TAS1R1 -1999
S1PR1 -1998
PTGFR -1993
DHH -1744
MTNR1B -1568
ADRA1A -1547
CGA -1451
CXCR2 -1396
GRP -1392
ADM2 -1274
SST -1272
ADRA2A -1225
P2RY6 -1176
WNT8A -1175
AVPR1A -1147
TACR2 -974
WNT4 -972
GNB4 -853
GHRL -634
GLP2R -618
OPRK1 -463
GPR68 -394
ADRB2 -309
ADORA1 -261
MTNR1A -198
WNT3A -166
NPSR1 -142
HTR1D -121
GPR39 -94
HTR4 -92
PLPPR5 -59
GHRHR -56
GRM8 -15
WNT6 155
CCKBR 157
OXER1 166
ADRA1B 184
P2RY14 218
TAS2R4 247
CCL13 294
WNT2B 364
GRM1 371
WNT3 476
FZD4 507
HRH1 509
TACR3 542
GPR17 621
APP 650
NMS 733
VIPR1 777
OPN5 783
MCHR1 785
RHO 795
TAS2R50 822
WNT10B 850
CHRM3 864
CXCR4 937
FZD3 968
PTGER1 1036
TAS2R38 1092
CX3CL1 1134
QRFPR 1286
PPBP 1287
ADRA2B 1409
PROKR2 1536
FZD7 1595
HCRTR1 1663
SSTR1 1682
CYSLTR2 1727
HTR2B 1775
TAS2R3 1859
GCG 1972
WNT11 1975
TACR1 1984
PENK 2034
MC4R 2121
C5AR2 2217
WNT8B 2252
WNT7A 2306
FFAR3 2328
CALCRL 2569
MC3R 2635
TAS2R10 2681
GNB3 2797
GNB2 2815
INSL3 2827
ADGRE1 2850
CNR1 2916
NTS 3035
RXFP3 3180
F2RL1 3211
CRHR1 3268
VIPR2 3342
FZD2 3344
TAS2R9 3352
GNG8 3600
HTR6 3621
EDNRA 3638
MLNR 3642
HTR7 3706
PDYN 3744
CORT 4004
GIPR 4013
CXCL6 4122
TAAR2 4155
HCRTR2 4223
FSHB 4327
GLP1R 4333
ANXA1 4428
NPY5R 4456
ADGRE3 4461
NPW 4681
HTR1F 4758
WNT16 4831
PTGER4 4850
TAS2R46 4886
DRD4 4922
CCR5 4925
FZD1 4935
S1PR5 4961
NPFFR2 5060
CCR2 5061
HEBP1 5104
CCL7 5153
HRH4 5163
WNT2 5247
TAAR8 5336
NLN 5474
GRM3 5493
TAS2R31 5495
PTGER2 5496
CALCR 5510
GPHA2 5572
GRM7 5586
GRM5 5692
FZD5 5802
RXFP1 5826
LPAR6 5845
LHCGR 5924
CCR4 5988
BDKRB1 6068
ACKR1 6100
GNRHR 6127
XCR1 6142
GPR31 6153
OPRM1 6259
TAS2R60 6273
GPR18 6276
C3AR1 6366
SSTR4 6374
TAAR1 6378
OXGR1 6395
RGR 6397
GPR37 6420
GNRH1 6488
PTHLH 6499
TAC3 6521
TAS2R13 6543
TSHB 6627
HTR1E 6735
TAS2R19 6736
CCR3 6817
GNG12 6818
SAA1 6821
OPN3 6889
ACKR4 6953
LHB 7079
FFAR1 7175
UTS2R 7218
PROK1 7248
ACKR3 7281
CCKAR 7287
CRHR2 7332
INSL5 7358
P2RY13 7413
ADORA2A 7442
OPN4 7449
FSHR 7455
FPR3 7458
FFAR2 7591
TAS2R41 7845
TAS2R1 7846
UTS2 7913
GIP 7953
NPS 7990
CCR8 7991
CNR2 8077
TAAR9 8164
TAAR6 8169
CCL11 8186
GNG13 8304
HCAR2 8332
CHRM5 8344
GPR65 8385
PTGER3 8401
TAS2R16 8406
WNT1 8425
OPRD1 8483
CXCL13 8489
TAS2R7 8520
CCL28 8578
TAS2R40 8629
UCN3 8766
ADRA2C 8833
IAPP 8834
PTH 8903
TAS2R42 8907
TAS2R43 8953
RRH 8991
CCR1 9046
NPB 9157
GNGT1 9233
OXT 9243
PTGIR 9270
RLN2 9437
FPR1 9622


REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS

REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS
1415
set REACTOME_BIOSYNTHESIS_OF_MARESIN_LIKE_SPMS
setSize 6
pANOVA 0.00975
s.dist 0.609
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
CYP2C8 8343
CYP2C9 8091
CYP3A4 6657
CYP2E1 6482
CYP2D6 6161
CYP1A2 -2361

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CYP2C8 8343
CYP2C9 8091
CYP3A4 6657
CYP2E1 6482
CYP2D6 6161
CYP1A2 -2361


REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3

REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
916
set REACTOME_ACTIVATED_PKN1_STIMULATES_TRANSCRIPTION_OF_AR_ANDROGEN_RECEPTOR_REGULATED_GENES_KLK2_AND_KLK3
setSize 59
pANOVA 0.00977
s.dist 0.194
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
KLK2 8575.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
KLK2 8575.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0
H3-3A 5167.0
H4C12 4671.0
KDM4C 4584.0
H2BC11 4341.0
KLK3 3526.0
H3C4 3221.0
H4C3 2803.0
H2AC7 2726.5
H2BC7 2726.5
H2BC12 1426.0
H2BC5 741.0
H4C16 326.0
H2BC9 -18.5
H3C7 -18.5
H4C9 -77.0
KDM1A -169.0
H2AZ1 -219.0
H3C8 -1195.0
H2BC4 -1847.0
H2AC6 -2387.0
NCOA2 -2737.0
H3C2 -3371.0
H2BC26 -3442.0
H2BC1 -4333.0
H4C13 -4551.0
H2AC8 -5188.0
H4C11 -5525.0
H2BC13 -5652.0
H3-3B -6496.0
H3C11 -6664.0
H2AC20 -8295.0
H2BC21 -8370.0
H2BC10 -8462.0
H3C10 -8504.0
H2AJ -8875.0
H4C2 -9517.0
H2BC8 -9562.0
H2BC15 -9905.0
PKN1 -10772.0


REACTOME_DEFENSINS

REACTOME_DEFENSINS
111
set REACTOME_DEFENSINS
setSize 33
pANOVA 0.0098
s.dist 0.26
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
DEFB128 9414.0
DEFB119 9361.0
DEFB129 9107.0
DEFB104A 9047.5
DEFB104B 9047.5
ART1 9023.0
DEFB114 8918.0
DEFB124 8354.0
DEFA6 8171.0
DEFB132 7803.0
DEFB115 7478.0
DEFB121 7370.0
DEFB116 6776.0
DEFB127 6720.0
DEFB110 5436.0
CCR2 5061.0
DEFB1 4562.0
DEFB125 4110.0
DEFB118 4106.0
DEFA5 3992.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
DEFB128 9414.0
DEFB119 9361.0
DEFB129 9107.0
DEFB104A 9047.5
DEFB104B 9047.5
ART1 9023.0
DEFB114 8918.0
DEFB124 8354.0
DEFA6 8171.0
DEFB132 7803.0
DEFB115 7478.0
DEFB121 7370.0
DEFB116 6776.0
DEFB127 6720.0
DEFB110 5436.0
CCR2 5061.0
DEFB1 4562.0
DEFB125 4110.0
DEFB118 4106.0
DEFA5 3992.0
DEFB113 3583.0
DEFB135 2489.0
DEFB126 -2321.0
DEFB134 -6237.0
TLR2 -6469.0
TLR1 -7330.0
DEFB133 -7394.0
DEFB136 -8699.0
CCR6 -8763.0
DEFB123 -11089.0
CD4 -11333.0
PRSS3 -11721.0
DEFA4 -12001.0


REACTOME_AQUAPORIN_MEDIATED_TRANSPORT

REACTOME_AQUAPORIN_MEDIATED_TRANSPORT
781
set REACTOME_AQUAPORIN_MEDIATED_TRANSPORT
setSize 51
pANOVA 0.00989
s.dist -0.209
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
AVP -12023.0
ADCY7 -11853.0
AQP6 -11685.0
AQP8 -11476.0
GNG11 -11464.0
AQP5 -11346.0
PRKACA -11338.0
GNG3 -10992.0
AQP3 -10845.0
ADCY4 -10769.0
AQP12A -10418.5
GNB1 -9556.0
ADCY1 -9465.0
PRKAR1A -8804.0
GNAS -8327.0
MIP -8118.0
GNG5 -7692.0
GNG4 -7396.0
AQP4 -7267.0
GNG10 -6722.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AVP -12023.0
ADCY7 -11853.0
AQP6 -11685.0
AQP8 -11476.0
GNG11 -11464.0
AQP5 -11346.0
PRKACA -11338.0
GNG3 -10992.0
AQP3 -10845.0
ADCY4 -10769.0
AQP12A -10418.5
GNB1 -9556.0
ADCY1 -9465.0
PRKAR1A -8804.0
GNAS -8327.0
MIP -8118.0
GNG5 -7692.0
GNG4 -7396.0
AQP4 -7267.0
GNG10 -6722.0
PRKACG -6681.0
AQP9 -6078.0
GNGT2 -6044.0
PRKAR2A -5493.0
GNB5 -5001.0
GNG2 -4850.0
MYO5B -4168.0
GNG7 -4167.0
ADCY5 -4086.0
PRKAR2B -2679.0
ADCY3 -2066.0
GNB4 -853.0
ADCY2 -724.0
AQP2 -185.0
RAB11A -30.0
RAB11FIP2 1493.0
ADCY9 2128.0
ADCY6 2694.0
GNB3 2797.0
GNB2 2815.0
PRKAR1B 3155.0
AQP1 3195.0
GNG8 3600.0
AQP7 4267.0
ADCY8 4687.0
PRKACB 6173.0
AQP11 6398.0
GNG12 6818.0
AQP10 7865.0
GNG13 8304.0
GNGT1 9233.0


REACTOME_CIRCADIAN_CLOCK

REACTOME_CIRCADIAN_CLOCK
683
set REACTOME_CIRCADIAN_CLOCK
setSize 68
pANOVA 0.00996
s.dist -0.181
p.adjustANOVA 0.511



Top enriched genes

Top 20 genes
GeneID Gene Rank
AVP -12023
MED1 -11515
PPP1CA -11495
CARM1 -11154
CRTC2 -11001
PER1 -10849
NFIL3 -10596
SREBF1 -10230
BHLHE41 -10229
ELOVL3 -10204
CSNK1D -9732
DBP -9657
NCOA6 -9593
SMARCD3 -9167
EP300 -9135
KLF15 -8965
TBL1XR1 -7172
CSNK1E -7161
CPT1A -6906
MEF2D -6586

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AVP -12023
MED1 -11515
PPP1CA -11495
CARM1 -11154
CRTC2 -11001
PER1 -10849
NFIL3 -10596
SREBF1 -10230
BHLHE41 -10229
ELOVL3 -10204
CSNK1D -9732
DBP -9657
NCOA6 -9593
SMARCD3 -9167
EP300 -9135
KLF15 -8965
TBL1XR1 -7172
CSNK1E -7161
CPT1A -6906
MEF2D -6586
CREB1 -6475
HELZ2 -6353
CREBBP -5580
RPS27A -5429
PPARA -4871
RAI1 -4820
CRTC3 -4766
RXRA -4727
PPP1CC -4710
ATF2 -4363
SIRT1 -4307
CREM -4173
SKP1 -3528
NPAS2 -3219
NCOR1 -2952
BMAL2 -2858
NR1D1 -2777
NOCT -2771
NCOA2 -2737
UBA52 -2492
UBC -1940
SERPINE1 -1762
BMAL1 -1507
HIF1A -1395
BTRC -1184
FBXL3 -1021
BHLHE40 -328
UBB -227
CRY1 636
HDAC3 859
RORA 1289
NCOA1 1808
PER2 2163
RBM4 2236
NR3C1 2559
CLOCK 2634
PPARGC1A 2728
CRY2 2930
F7 4323
CHD9 4810
CRTC1 4868
NRIP1 5152
NAMPT 5174
PPP1CB 5222
MEF2C 5339
CUL1 5793
TGS1 6566
USP46 7231


REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS

REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS
790
set REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS
setSize 16
pANOVA 0.0108
s.dist -0.368
p.adjustANOVA 0.529



Top enriched genes

Top 20 genes
GeneID Gene Rank
VASP -11225
ITGB1 -9802
FLNC -9745
ACTB -9512
PXN -9340
PARVA -8958
LIMS1 -7400
RSU1 -7240
FERMT2 -5275
ACTN1 -5243
LIMS2 -4628
PARVB -4285
ACTG1 -2441
TESK1 -289
ILK 5381
FBLIM1 7004

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
VASP -11225
ITGB1 -9802
FLNC -9745
ACTB -9512
PXN -9340
PARVA -8958
LIMS1 -7400
RSU1 -7240
FERMT2 -5275
ACTN1 -5243
LIMS2 -4628
PARVB -4285
ACTG1 -2441
TESK1 -289
ILK 5381
FBLIM1 7004


REACTOME_METABOLISM_OF_LIPIDS

REACTOME_METABOLISM_OF_LIPIDS
880
set REACTOME_METABOLISM_OF_LIPIDS
setSize 709
pANOVA 0.011
s.dist -0.0561
p.adjustANOVA 0.529



Top enriched genes

Top 20 genes
GeneID Gene Rank
GPX2 -11898
TPTE -11894
GPAT2 -11818
FITM1 -11700
PNPLA2 -11636
MOGAT2 -11591
PTGDS -11589
G0S2 -11535
MED1 -11515
PPP1CA -11495
PLA1A -11462
GPD1 -11452
TNFAIP8L1 -11435
PRKACA -11338
LPCAT4 -11321
PISD -11275
PLPP2 -11260
ACOX2 -11227
LIPH -11182
PLA2G4F -11155

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GPX2 -11898
TPTE -11894
GPAT2 -11818
FITM1 -11700
PNPLA2 -11636
MOGAT2 -11591
PTGDS -11589
G0S2 -11535
MED1 -11515
PPP1CA -11495
PLA1A -11462
GPD1 -11452
TNFAIP8L1 -11435
PRKACA -11338
LPCAT4 -11321
PISD -11275
PLPP2 -11260
ACOX2 -11227
LIPH -11182
PLA2G4F -11155
CARM1 -11154
CHKB -11147
CSNK1G2 -11078
DPEP2 -11042
SEC24C -11003
HMGCS2 -10998
ACSBG1 -10984
DGAT2 -10859
SPNS2 -10840
MED7 -10830
DGAT1 -10797
ECI1 -10794
ETNPPL -10744
EHHADH -10706
CYP17A1 -10663
AGPAT2 -10656
ALDH3B2 -10603
SIN3B -10565
ACOT2 -10502
AGT -10501
NR1H3 -10493
PLA2G2E -10460
PTPMT1 -10431
ACER2 -10413
TSPOAP1 -10353
MED24 -10300
LPIN2 -10274
CYP27B1 -10270
PLA2G15 -10261
CPT2 -10250
OSBPL1A -10234
SREBF1 -10230
ELOVL3 -10204
CERK -10169
ORMDL3 -10149
GPD2 -10056
SYNJ2 -9931
ACOT6 -9908
INPP5D -9904
GBA2 -9902
ECI2 -9861
HILPDA -9841
PLPP6 -9825
UBE2I -9780
SLC27A3 -9766
CYP4F22 -9681
PGS1 -9677
PIP5K1A -9675
ACAT1 -9661
NCOA6 -9593
HSD3B7 -9557
THEM5 -9537
APOA5 -9474
MED6 -9448
DHRS7B -9445
DPEP1 -9396
NCOR2 -9383
LSS -9361
GLIPR1 -9346
DEGS2 -9306
PLD6 -9259
HSD17B11 -9255
STAR -9222
PTGS1 -9216
ACAD10 -9197
SMARCD3 -9167
GRHL1 -9164
STARD4 -9154
EP300 -9135
HMGCL -9120
RXRB -9089
ALOX5AP -9077
PLD1 -9056
MED13L -9011
PTGS2 -8943
PLA2G4B -8938
SAMD8 -8930
PCYT2 -8871
CPT1B -8862
LBR -8836
ESYT3 -8817
PIK3CD -8794
PIK3C2B -8718
INSIG2 -8657
TSPO -8650
PLA2G4E -8627
OSBPL2 -8626
HMGCS1 -8614
LGMN -8600
CYP4F3 -8569
INPP4A -8564
PPT1 -8562
GK2 -8541
LTC4S -8537
ARSA -8494
SEC23A -8438
CYP27A1 -8435
MMAA -8352
CYP1A1 -8325
ASAH1 -8307
ARSI -8210
INPP5F -8195
CRLS1 -8190
PTGES -8159
GDPD3 -8140
CPNE6 -8094
CERS3 -8084
TNFRSF21 -8002
PI4K2B -7993
PIK3R4 -7954
SLC27A1 -7926
PLIN3 -7908
ALOX5 -7874
AGPAT5 -7860
ESYT2 -7835
SELENOI -7833
ABCB11 -7810
ACADS -7776
PLA2G4D -7754
ARF3 -7715
FABP3 -7706
LIPE -7694
PLA2G2D -7660
ACSM3 -7644
ELOVL4 -7633
OSBPL7 -7630
PTGIS -7629
ABCC3 -7575
PLAAT5 -7521
STARD6 -7509
ALOX12B -7412
CYP46A1 -7387
GPD1L -7303
CSNK2A1 -7248
PITPNM1 -7247
DECR2 -7236
ACSM6 -7234
ACOXL -7230
PIK3R5 -7226
POMC -7216
TBL1XR1 -7172
LPCAT1 -7123
SPTSSA -7115
MTMR9 -7108
PITPNB -7106
NEU3 -7090
CSNK2A2 -7081
ACADVL -7048
NEU2 -7031
SC5D -6990
CYP2R1 -6920
CPT1A -6906
B4GALNT1 -6879
ACAA1 -6860
MED10 -6825
NUDT19 -6806
FIG4 -6797
MTMR4 -6769
MFSD2A -6749
SLC27A5 -6747
MED19 -6735
SUMF1 -6721
PTGR1 -6720
MED31 -6713
TXNRD1 -6712
ACSL5 -6683
PRKACG -6681
CERS1 -6621
MBOAT2 -6619
ABHD4 -6617
GLB1 -6602
MED15 -6598
SUMO2 -6595
DPEP3 -6585
ARF1 -6582
HEXA -6568
PLD3 -6532
PNPLA3 -6527
ETNK2 -6495
ACOT12 -6444
ACBD4 -6439
CHKA -6426
PLEKHA2 -6412
HELZ2 -6353
HPGD -6339
TNFAIP8 -6318
OSBPL5 -6283
GGT1 -6273
SP1 -6270
PCCA -6254
CPNE3 -6252
PI4KB -6240
SERPINA6 -6224
LTA4H -6124
SBF1 -6080
SULT2A1 -6048
VDR -6017
PLA2G12A -6016
NFYB -6001
ABHD5 -5968
PIP5K1C -5908
ELOVL2 -5902
MVD -5800
PIK3R2 -5785
FABP12 -5769
CYP2C19 -5754
RAB5A -5749
PLEKHA3 -5684
AGK -5636
ESYT1 -5623
HACL1 -5604
CREBBP -5580
PIK3CB -5554
GPX1 -5537
STARD10 -5492
SLC51A -5475
HADHA -5459
AGPAT3 -5372
MED18 -5340
ACER1 -5329
ACADM -5249
MED26 -5221
CYP2U1 -5197
LPGAT1 -5193
PRKD2 -5191
CHAT -5128
PLD2 -5102
DEGS1 -5048
ARNT2 -5025
SLC44A4 -4933
ACADL -4910
TMEM86B -4899
FDX2 -4885
MED23 -4882
CPNE7 -4876
PPARA -4871
PRKD3 -4856
PSAP -4848
ABCC1 -4831
GPAT4 -4828
OSBPL9 -4782
PHYH -4779
CYP11A1 -4753
PLEKHA4 -4745
PTEN -4735
RXRA -4727
PPP1CC -4710
CDS1 -4641
MGLL -4627
SCD5 -4620
HMGCR -4590
PLEKHA6 -4582
CYP19A1 -4519
MTMR14 -4485
HSD17B8 -4483
FDFT1 -4481
PI4K2A -4453
SCAP -4421
LPCAT2 -4371
PIKFYVE -4305
ESRRA -4280
ACOT1 -4267
PRKAA2 -4248
FITM2 -4181
PLAAT3 -4166
GPX4 -4125
SGPP1 -4118
ALOXE3 -4097
PLAAT1 -4074
MED8 -4053
PPT2 -4051
CERS6 -4038
NUDT7 -4026
ABCB4 -4017
EPHX2 -3971
LDLRAP1 -3921
SIN3A -3798
PPARGC1B -3789
RAB14 -3750
ACACB -3742
PLEKHA8 -3736
SGMS1 -3698
HSD17B1 -3694
MTF1 -3661
PLBD1 -3626
PTGES2 -3602
STARD3 -3483
GGT5 -3453
TM7SF2 -3411
CYP11B2 -3404
ELOVL5 -3369
OXCT1 -3339
PCCB -3321
CERT1 -3317
DBI -3296
ARNT -3292
PTPN13 -3278
CROT -3266
CPNE1 -3248
PIK3C3 -3232
NPAS2 -3219
GALC -3208
PITPNM2 -3203
THEM4 -3169
SCP2 -3135
SLC22A5 -3035
PNPLA7 -3020
PEMT -3015
SREBF2 -3010
INPPL1 -2996
MED20 -2983
MED17 -2977
PIK3R6 -2969
NCOR1 -2952
PON3 -2940
ELOVL1 -2901
PLEKHA1 -2866
MED29 -2836
ENPP7 -2832
AGPAT1 -2820
ALDH3B1 -2818
PRKAG2 -2800
NR1D1 -2777
HSD11B2 -2765
NCOA2 -2737
PTGES3 -2688
NFYC -2666
CERS2 -2583
CYP4F8 -2568
B3GALNT1 -2553
CDS2 -2550
CDK8 -2549
PIAS4 -2524
PNPLA6 -2479
MIGA2 -2466
CRAT -2432
CYP1A2 -2361
ACSL6 -2310
MCAT -2253
SQLE -2231
GGPS1 -2220
ACSF3 -2217
FAR1 -2098
HSD17B4 -1959
SPTSSB -1926
SLC27A2 -1909
FAM120B -1900
INPP4B -1874
TIAM2 -1868
HACD3 -1848
PMVK -1766
ANGPTL4 -1680
FADS1 -1659
SLC44A1 -1653
MTMR3 -1614
GLB1L -1608
PLA2R1 -1581
CSNK2B -1517
BMAL1 -1507
CIDEA -1498
SEC24A -1482
PLIN2 -1470
SLC25A1 -1469
FDX1 -1466
OSBPL3 -1457
KDSR -1455
CGA -1451
UGCG -1446
SEC24D -1391
MED22 -1350
ALOX15B -1341
SRD5A2 -1308
SLC25A17 -1271
MTMR7 -1191
ANKRD1 -1100
INPP5E -1045
NR1H2 -1019
AACS -1011
PNPLA5 -997
BDH2 -977
CYP4F2 -965
VAPB -960
MECR -944
MBOAT1 -943
GDPD5 -924
MTMR6 -918
MED27 -904
CD36 -823
PON2 -812
ECHS1 -679
FA2H -614
ARSK -613
LPIN3 -609
PCYT1A -571
ALAS1 -551
ALPI -547
FDPS -518
FADS2 -514
FABP6 -456
AKR1D1 -433
GBA1 -424
HSD3B2 -408
STARD3NL -380
PLA2G4C -333
SGMS2 -314
FAR2 -299
PNPLA8 -258
CCNC -239
FASN -228
CUBN -179
ACBD5 -101
ACSL1 -33
MLYCD -20
SEC24B -7
ACHE 47
SACM1L 69
RAB4A 152
ELOVL7 196
SMPD3 204
CTSA 229
SAR1B 262
SLC44A2 265
CBR4 290
CHPT1 300
MIGA1 323
ACAD11 335
PITPNM3 368
HSD17B14 379
MED28 420
DECR1 461
MED30 583
BDH1 620
FAAH 771
HDAC3 859
PLA2G6 882
ACOX3 910
HEXB 1019
PIK3R3 1089
ACOT7 1110
PI4KA 1111
GDPD1 1162
SLC25A20 1191
GPS2 1247
MSMO1 1256
GDE1 1288
RORA 1289
PLA2G4A 1299
PTDSS2 1394
PPARD 1401
ARV1 1421
HSD17B13 1456
HPGDS 1495
OSBPL10 1566
CPTP 1690
ACOT11 1741
TNFAIP8L3 1765
NCOA1 1808
HACD4 1835
CERS5 1968
PLAAT4 2000
FABP9 2002
MAPKAPK2 2008
AKR1C1 2071
RGL1 2115
DDHD1 2118
CEPT1 2126
CYP21A2 2127
FDXR 2129
CH25H 2183
LRP2 2187
ALOX12 2190
ACACA 2194
CYP7A1 2201
ACLY 2212
MOGAT3 2224
ACAA2 2232
INSIG1 2251
PIK3CA 2278
PLPP1 2305
ALOX15 2339
PEX11A 2348
MMUT 2447
AHR 2471
FHL2 2505
LPIN1 2507
HADHB 2515
GM2A 2557
PPARG 2594
TBXAS1 2611
CLOCK 2634
THRAP3 2649
LPCAT3 2666
CYP39A1 2672
MCEE 2724
PPARGC1A 2728
IDI1 2734
ALB 2817
SPTLC1 2826
PLA2G3 2861
UGT1A9 2869
CYP51A1 2872
HSD17B12 2920
MED11 2938
SPHK2 2958
PLB1 2966
ACOT8 2978
TECR 2980
SCD 3005
SPTLC2 3030
AGPAT4 3080
GSTM4 3282
PLD4 3510
MED25 3590
MED9 3615
ACSF2 3622
HADH 3623
CDIPT 3663
PLPP3 3702
OSBPL6 3768
PIK3R1 3776
NRF1 3854
ACOT13 3874
FABP5 3903
SBF2 3930
SRD5A3 3980
SRD5A1 4017
AGPS 4056
VAC14 4096
MBOAT7 4126
ENPP6 4145
OSBPL8 4160
CYP8B1 4178
ARSB 4196
SGPP2 4356
ACOX1 4402
MOGAT1 4410
ABCA1 4451
SYNJ1 4474
NEU1 4480
CYP1B1 4541
MORC2 4570
ARSJ 4572
AKR1B15 4582
PIP4P1 4650
ACSL3 4655
ORMDL1 4668
GNPAT 4734
CERS4 4746
CHD9 4810
DHCR24 4816
GLTP 4825
ARSG 4847
PTGR2 4920
HSD11B1 4956
IDI2 4982
PLA2G1B 4991
PRKD1 5068
RUFY1 5144
NFYA 5156
PPP1CB 5222
CDK19 5251
ACBD7 5299
MED21 5329
ACSS3 5484
ELOVL6 5581
HACD2 5585
KPNB1 5625
PIK3C2A 5650
APOA1 5670
PIP5K1B 5694
ACOT4 5695
HMGCLL1 5765
PON1 5813
CAV1 5851
UGT8 5904
NR1H4 5905
SGPL1 5935
SLC44A5 5946
DHCR7 5955
PIP4K2B 5977
AGMO 5980
PCTP 6009
PLEKHA5 6051
GC 6080
MTMR12 6094
PECR 6135
CYP2D6 6161
PRKACB 6173
GPAM 6195
CYP24A1 6198
STARD5 6227
HSD17B2 6235
SPHK1 6246
PTDSS1 6278
ETNK1 6302
MBTPS1 6320
SLC10A1 6380
THRSP 6414
MTMR2 6439
NDUFAB1 6471
SMPD1 6475
CYP2E1 6482
PIP4K2A 6490
PLA2G2A 6493
SLC44A3 6507
TGS1 6566
NCOA3 6593
FABP7 6631
AMACR 6646
CYP3A4 6657
SLC51B 6708
ABHD3 6772
TPTE2 6792
TRIB3 6797
CYP7B1 6813
SUMF2 6830
CBR1 6842
MED4 6862
HSD17B7 6882
PPM1L 6897
PIK3C2G 6910
OLAH 6918
SPTLC3 6926
RAN 6947
TNFAIP8L2 7029
HACD1 7039
ME1 7047
AKR1B1 7049
LHB 7079
SLCO1B1 7092
ACSBG2 7164
MED13 7178
INPP5J 7313
CIDEC 7406
SMPD2 7418
ORMDL2 7425
INPP5K 7430
GPCPD1 7445
HSD3B1 7461
ACBD6 7505
PIK3CG 7520
CYP4B1 7523
PLA2G5 7529
NEU4 7533
SLCO1A2 7603
ACAT2 7611
APOA2 7616
CYP4F11 7681
PLIN1 7712
HSD17B3 7724
FABP1 7751
MVK 7813
MED16 7899
SLCO1B3 7984
ALDH3A2 8026
ASAH2 8067
CYP2C9 8091
VAPA 8100
LCLAT1 8125
ACER3 8140
MTMR10 8152
CYP2J2 8155
PHOSPHO1 8157
PRKAB2 8258
ACP6 8277
OSBP 8278
DDHD2 8341
CYP2C8 8343
SMPD4 8355
STARD7 8379
PIP4K2C 8382
CYP4A22 8467
AKR1C3 8498
PRXL2B 8511
PLAAT2 8623
AKR1C2 8639
CYP11B1 8709
BCHE 8810
FABP4 8965
PLA2G10 8967
LIPI 9009
AKR1C4 9073
FABP2 9116
TECRL 9206
HAO2 9328
SLC10A2 9382
CYP4A11 9465
PLA2G2F 9556
BAAT 9675


REACTOME_LEISHMANIA_INFECTION

REACTOME_LEISHMANIA_INFECTION
1509
set REACTOME_LEISHMANIA_INFECTION
setSize 156
pANOVA 0.0122
s.dist -0.116
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
PYCARD -11396
FURIN -11356
PRKACA -11338
DPEP2 -11042
GNG3 -10992
CTSG -10820
RELA -10818
ADCY4 -10769
GNAI2 -10681
CD247 -10495
NLRP3 -9992
ADORA2B -9910
ARPC4 -9671
MAPK3 -9613
GNB1 -9556
ACTB -9512
ADCY1 -9465
DPEP1 -9396

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
PYCARD -11396
FURIN -11356
PRKACA -11338
DPEP2 -11042
GNG3 -10992
CTSG -10820
RELA -10818
ADCY4 -10769
GNAI2 -10681
CD247 -10495
NLRP3 -9992
ADORA2B -9910
ARPC4 -9671
MAPK3 -9613
GNB1 -9556
ACTB -9512
ADCY1 -9465
DPEP1 -9396
MYO9B -9374
RAC1 -9215
CYFIP1 -8904
GNAI3 -8894
PRKAR1A -8804
C3 -8646
GNAS -8327
SRC -8020
ADAM17 -7843
GNG5 -7692
FGR -7507
GSDMD -7410
GNG4 -7396
RHBDF2 -7322
CD163 -7180
VAV1 -7135
WNT5A -6950
WIPF1 -6883
MAPK1 -6855
GNG10 -6722
PRKACG -6681
DPEP3 -6585
CYBA -6497
ENTPD1 -6488
CREB1 -6475
ARPC1B -6371
GGT1 -6273
MYO5A -6222
IL1A -6115
HCK -6054
GNGT2 -6044
ITPR3 -6012
CRK -5923
PLCG2 -5798
MEFV -5770
PSTPIP1 -5514
HMOX1 -5508
PRKAR2A -5493
GNB5 -5001
GNG2 -4850
PLK2 -4808
BAIAP2 -4445
YES1 -4430
DOCK1 -4424
ABL1 -4263
NCKAP1L -4254
ACTR3 -4236
NCK1 -4222
BRK1 -4189
GNG7 -4167
GNAI1 -4123
ADCY5 -4086
WIPF2 -4039
MYO1C -3880
ABI1 -3800
ITPR2 -3785
WIPF3 -3692
HSP90AB1 -3657
GGT5 -3453
FYN -3338
CYFIP2 -3330
ARPC2 -3235
DVL1 -3194
NOXA1 -3070
PRKAR2B -2679
DVL3 -2609
ITPR1 -2499
ACTG1 -2441
CALM1 -2218
ADCY3 -2066
ENTPD5 -1841
ELMO2 -1710
DVL2 -1254
MAPK8 -1052
MYH9 -874
GNB4 -853
ADCY2 -724
VAV3 -291
ELMO1 -190
PTK2 -62
MYO10 301
GNAZ 555
APP 650
ARPC3 717
IL6 738
NOXO1 748
ACTR2 1150
WASF2 1199
LYN 1258
P2RX4 1315
ARPC1A 1412
FCGR3A 1480
FZD7 1595
CYSLTR2 1727
PLCG1 1779
CASP1 1950
GNAT3 2081
ADCY9 2128
SYK 2191
NFKB1 2237
MAPK14 2381
P2RX7 2403
ADCY6 2694
AHCYL1 2773
GNB3 2797
GNB2 2815
TXNIP 2957
PRKAR1B 3155
NFKB2 3228
GRB2 3310
GNG8 3600
TXN 4216
IL18 4237
CDC42 4288
NT5E 4415
ADCY8 4687
NCKAP1 4733
WASL 5102
SUGT1 5615
NCKIPSD 6071
PRKACB 6173
ARPC5 6327
C3AR1 6366
VAV2 6477
JUN 6753
GNG12 6818
WASF3 7114
ABI2 7876
MYH2 7956
GNG13 8304
FCGR2A 8403
WASF1 9159
GNGT1 9233
IL10 9516
CD3G 9544
IL1B 9587


REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS

REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS
130
set REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS
setSize 123
pANOVA 0.0126
s.dist -0.13
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
GPAT2 -11818
PNPLA2 -11636
PLA1A -11462
GPD1 -11452
LPCAT4 -11321
PISD -11275
LIPH -11182
PLA2G4F -11155
CHKB -11147
DGAT2 -10859
DGAT1 -10797
ETNPPL -10744
AGPAT2 -10656
PLA2G2E -10460
PTPMT1 -10431
LPIN2 -10274
PLA2G15 -10261
GPD2 -10056
PGS1 -9677
PLD6 -9259

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GPAT2 -11818
PNPLA2 -11636
PLA1A -11462
GPD1 -11452
LPCAT4 -11321
PISD -11275
LIPH -11182
PLA2G4F -11155
CHKB -11147
DGAT2 -10859
DGAT1 -10797
ETNPPL -10744
AGPAT2 -10656
PLA2G2E -10460
PTPMT1 -10431
LPIN2 -10274
PLA2G15 -10261
GPD2 -10056
PGS1 -9677
PLD6 -9259
PLD1 -9056
PLA2G4B -8938
PCYT2 -8871
PLA2G4E -8627
CRLS1 -8190
CPNE6 -8094
AGPAT5 -7860
SELENOI -7833
PLA2G4D -7754
PLA2G2D -7660
PLAAT5 -7521
GPD1L -7303
CSNK2A1 -7248
PITPNM1 -7247
LPCAT1 -7123
PITPNB -7106
CSNK2A2 -7081
MFSD2A -6749
MBOAT2 -6619
ABHD4 -6617
PLD3 -6532
PNPLA3 -6527
ETNK2 -6495
CHKA -6426
OSBPL5 -6283
CPNE3 -6252
PLA2G12A -6016
AGK -5636
STARD10 -5492
HADHA -5459
AGPAT3 -5372
LPGAT1 -5193
CHAT -5128
PLD2 -5102
SLC44A4 -4933
TMEM86B -4899
CPNE7 -4876
GPAT4 -4828
CDS1 -4641
MGLL -4627
LPCAT2 -4371
PLAAT3 -4166
PLAAT1 -4074
PLBD1 -3626
CPNE1 -3248
PITPNM2 -3203
PEMT -3015
AGPAT1 -2820
CDS2 -2550
MIGA2 -2466
SLC44A1 -1653
PLA2R1 -1581
CSNK2B -1517
MBOAT1 -943
LPIN3 -609
PCYT1A -571
ALPI -547
PLA2G4C -333
PNPLA8 -258
ACHE 47
SLC44A2 265
CHPT1 300
MIGA1 323
PITPNM3 368
PLA2G6 882
PLA2G4A 1299
PTDSS2 1394
OSBPL10 1566
PLAAT4 2000
DDHD1 2118
CEPT1 2126
LPIN1 2507
HADHB 2515
LPCAT3 2666
PLA2G3 2861
PLB1 2966
AGPAT4 3080
PLD4 3510
CDIPT 3663
MBOAT7 4126
OSBPL8 4160
GNPAT 4734
PLA2G1B 4991
SLC44A5 5946
PCTP 6009
GPAM 6195
PTDSS1 6278
ETNK1 6302
PLA2G2A 6493
SLC44A3 6507
ABHD3 6772
GPCPD1 7445
PLA2G5 7529
LCLAT1 8125
PHOSPHO1 8157
ACP6 8277
DDHD2 8341
STARD7 8379
PLAAT2 8623
BCHE 8810
PLA2G10 8967
LIPI 9009
PLA2G2F 9556


REACTOME_RORA_ACTIVATES_GENE_EXPRESSION

REACTOME_RORA_ACTIVATES_GENE_EXPRESSION
93
set REACTOME_RORA_ACTIVATES_GENE_EXPRESSION
setSize 17
pANOVA 0.0126
s.dist -0.349
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
MED1 -11515
CARM1 -11154
SREBF1 -10230
NCOA6 -9593
SMARCD3 -9167
EP300 -9135
TBL1XR1 -7172
CPT1A -6906
HELZ2 -6353
CREBBP -5580
PPARA -4871
RXRA -4727
NCOA2 -2737
RORA 1289
NCOA1 1808
CHD9 4810
TGS1 6566

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MED1 -11515
CARM1 -11154
SREBF1 -10230
NCOA6 -9593
SMARCD3 -9167
EP300 -9135
TBL1XR1 -7172
CPT1A -6906
HELZ2 -6353
CREBBP -5580
PPARA -4871
RXRA -4727
NCOA2 -2737
RORA 1289
NCOA1 1808
CHD9 4810
TGS1 6566


REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION

REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
1091
set REACTOME_ASSEMBLY_OF_THE_ORC_COMPLEX_AT_THE_ORIGIN_OF_REPLICATION
setSize 62
pANOVA 0.0128
s.dist 0.183
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
KPNA6 7200.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
KPNA6 7200.0
H2AX 7192.0
H3C6 6884.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0
KPNB1 5625.0
H3-3A 5167.0
H4C12 4671.0
KPNA1 4381.0
H2BC11 4341.0
H3C4 3221.0
H4C3 2803.0
H2AC7 2726.5
H2BC7 2726.5
ORC1 2051.0
H2BC12 1426.0
H2BC5 741.0
H4C16 326.0
H2BC9 -18.5
H3C7 -18.5
H4C9 -77.0
H2AZ1 -219.0
H3C8 -1195.0
ORC4 -1573.0
H2BC4 -1847.0
ORC6 -1891.0
H2AC6 -2387.0
H3C2 -3371.0
H2BC26 -3442.0
ORC2 -4073.0
H2BC1 -4333.0
H4C13 -4551.0
ORC3 -4693.0
H2AC8 -5188.0
H4C11 -5525.0
H2BC13 -5652.0
H3-3B -6496.0
H3C11 -6664.0
H2AC20 -8295.0
H2BC21 -8370.0
H2BC10 -8462.0
H3C10 -8504.0
H2AJ -8875.0
ORC5 -8988.0
H4C2 -9517.0
H2BC8 -9562.0
H2BC15 -9905.0


REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES

REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES
55
set REACTOME_ROS_AND_RNS_PRODUCTION_IN_PHAGOCYTES
setSize 34
pANOVA 0.013
s.dist -0.246
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
ATP6V1E2 -11469
RAC2 -11337
ATP6V0C -11115
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
ATP6V0A1 -9864
NCF4 -9857
ATP6V1E1 -9547
ATP6V0B -9464
MPO -8729
ATP6V1C2 -8680
ATP6V0A2 -8252
ATP6V1C1 -7442
NCF2 -6592
CYBA -6497
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
ATP6V1G3 -1735

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ATP6V1E2 -11469
RAC2 -11337
ATP6V0C -11115
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
ATP6V0A1 -9864
NCF4 -9857
ATP6V1E1 -9547
ATP6V0B -9464
MPO -8729
ATP6V1C2 -8680
ATP6V0A2 -8252
ATP6V1C1 -7442
NCF2 -6592
CYBA -6497
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
ATP6V1G3 -1735
SLC11A1 -1733
NOS3 -334
LPO -290
ATP6V1F 288
TCIRG1 669
NOS1 1446
ATP6V0A4 1648
ATP6V1B1 1697
NOS2 2391
ATP6V1G1 3618
HVCN1 4175
ATP6V1A 5106
ATP6V1D 5637
ATP6V0D2 9100


REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH

REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
1502
set REACTOME_DISEASES_OF_PROGRAMMED_CELL_DEATH
setSize 96
pANOVA 0.0136
s.dist 0.146
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
PRIM1 8363.0
H4C1 8144.0
SUZ12 7935.0
H2BC17 7929.0
H2AC4 7772.0
DNMT3B 7744.0
H4C8 7688.0
CDK5 7549.0
C1QBP 7469.0
MLKL 7396.0
H2AX 7192.0
H3C6 6884.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
PRIM1 8363.0
H4C1 8144.0
SUZ12 7935.0
H2BC17 7929.0
H2AC4 7772.0
DNMT3B 7744.0
H4C8 7688.0
CDK5 7549.0
C1QBP 7469.0
MLKL 7396.0
H2AX 7192.0
H3C6 6884.0
JUN 6753.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
CAPNS1 6085.0
H2AZ2 6053.0
H4C4 5750.0
CDC25A 5630.0
YWHAE 5594.0
H3-3A 5167.0
H4C12 4671.0
PRIM2 4646.0
H2BC11 4341.0
PRDX1 3839.0
CDK5R1 3303.0
H3C4 3221.0
H4C3 2803.0
H2AC7 2726.5
H2BC7 2726.5
EED 2444.0
GOLGA2 2219.0
LMNA 2155.0
EZH2 1982.0
H2BC12 1426.0
CAPN2 868.0
H2BC5 741.0
APP 650.0
H4C16 326.0
FOXO3 270.0
H2BC9 -18.5
H3C7 -18.5
H4C9 -77.0
H2AZ1 -219.0
LMNB1 -257.0
CDC25B -902.0
H3C8 -1195.0
RBBP4 -1450.0
TRADD -1479.0
H2BC4 -1847.0
FADD -2386.0
H2AC6 -2387.0
BCL2L11 -2398.0
CAPNS2 -2902.0
CDC25C -3161.0
H3C2 -3371.0
H2BC26 -3442.0
FASLG -3469.0
PRDX2 -3548.0
H2BC1 -4333.0
H4C13 -4551.0
CAPN1 -4567.0
TP53 -4747.0
DNMT3A -5041.0
POLA2 -5059.0
CDKN2A -5177.0
H2AC8 -5188.0
TRAF2 -5377.0
GSDME -5431.0
H4C11 -5525.0
H2BC13 -5652.0
SOD2 -5729.0
H3-3B -6496.0
H3C11 -6664.0
CASP8 -6741.0
RIPK1 -7931.0
RIPK3 -8122.0
H2AC20 -8295.0
H2BC21 -8370.0
H2BC10 -8462.0
H3C10 -8504.0
DNMT1 -8695.0
H2AJ -8875.0
H4C2 -9517.0
H2BC8 -9562.0
H2BC15 -9905.0
CAST -10127.0


REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES

REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES
622
set REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES
setSize 48
pANOVA 0.014
s.dist -0.205
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
HYOU1 -11763
DDX11 -11737
PREB -11374
SYVN1 -10698
ATP6V0D1 -10139
KLHDC3 -10044
CXXC1 -8979
PLA2G4B -8938
EXTL2 -8171
CUL7 -7997
GOSR2 -7802
SHC1 -7445
ACADVL -7048
MYDGF -6852
YIF1A -6732
TLN1 -6730
SSR1 -5819
EXTL1 -5529
SEC31A -5438
SRPRA -5334

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HYOU1 -11763
DDX11 -11737
PREB -11374
SYVN1 -10698
ATP6V0D1 -10139
KLHDC3 -10044
CXXC1 -8979
PLA2G4B -8938
EXTL2 -8171
CUL7 -7997
GOSR2 -7802
SHC1 -7445
ACADVL -7048
MYDGF -6852
YIF1A -6732
TLN1 -6730
SSR1 -5819
EXTL1 -5529
SEC31A -5438
SRPRA -5334
ADD1 -5106
DNAJB11 -4963
GFPT1 -4286
WFS1 -3625
DNAJC3 -3433
ERN1 -3350
PDIA5 -2960
GSK3A -2845
EDEM1 -2233
DCTN1 -2036
SERP1 -1233
SRPRB -1119
HDGF -1085
XBP1 -528
CTDSP2 143
KDELR3 1410
WIPI1 1529
ZBTB17 1738
ARFGAP1 2089
LMNA 2155
FKBP14 2613
PDIA6 2923
EXTL3 3129
PPP2R5B 4085
HSPA5 4414
DNAJB9 4492
TPP1 4579
TATDN2 5327


REACTOME_BIOLOGICAL_OXIDATIONS

REACTOME_BIOLOGICAL_OXIDATIONS
427
set REACTOME_BIOLOGICAL_OXIDATIONS
setSize 210
pANOVA 0.0142
s.dist 0.0981
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
GSTA1 9821
ACSM2A 9672
CYP2B6 9621
CYP4A11 9465
UGT2B7 9321
ALDH1B1 9223
UGT2B11 9149
ADH1B 9074
CYP4F12 9051
CYP2C18 8937
TPMT 8869
UGT2B4 8860
ACSM1 8828
ALDH3A1 8731
CYP11B1 8709
CYP4A22 8467
CYP2C8 8343
AKR7L 8232
SULT1B1 8167
CYP2J2 8155

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GSTA1 9821
ACSM2A 9672
CYP2B6 9621
CYP4A11 9465
UGT2B7 9321
ALDH1B1 9223
UGT2B11 9149
ADH1B 9074
CYP4F12 9051
CYP2C18 8937
TPMT 8869
UGT2B4 8860
ACSM1 8828
ALDH3A1 8731
CYP11B1 8709
CYP4A22 8467
CYP2C8 8343
AKR7L 8232
SULT1B1 8167
CYP2J2 8155
CYP2C9 8091
GSTA3 8055
AKR7A2 7955
ACSM2B 7925
FMO3 7919
UGT1A1 7905
N6AMT1 7856
CYP4F11 7681
ESD 7532
CYP4B1 7523
MTARC1 7496
CHAC1 7429
GSTA5 7354
UGT2A1 7263
GSTA4 6975
UGT1A4 6875
CYP7B1 6813
UGT1A3 6667
CYP3A4 6657
CYP4V2 6530
CYP2E1 6482
SULT1C4 6305
CYP26A1 6213
CYP24A1 6198
CYP2D6 6161
UGT1A5 5973
ADH5 5961
NR1H4 5905
CES2 5889
TRMT112 5801
GSTP1 5685
MAT2A 5621
EPHX1 5462
UGT2A2 5460
SULT1A1 5451
MGST1 5280
GLYAT 5228
ADH7 4697
MAT1A 4696
CYP1B1 4541
ADH4 4538
GLYATL2 4412
SLC26A2 4406
UGT1A8 4361
CYB5B 4321
UGT1A10 4284
FMO2 4215
CYP8B1 4178
CYP2W1 4079
BPHL 3868
UGT3A1 3842
SLC35D1 3592
CMBL 3330
GSTM4 3282
GLYATL3 3069
CYP51A1 2872
UGT1A9 2869
ABHD10 2690
CYP39A1 2672
CYP26B1 2648
AS3MT 2633
TBXAS1 2611
AHR 2471
UGT1A7 2362
BPNT1 2319
CYP7A1 2201
FDXR 2129
CYP21A2 2127
SULT4A1 1986
CES3 1842
UGT1A6 1838
NCOA1 1808
HPGDS 1495
AHCY 1424
ADH6 1195
GGCT 1168
ACSM4 953
MTR 856
CHAC2 96
CBR3 89
GSTO2 13
AKR7A3 -134
MTARC2 -245
NAT1 -326
GCLC -465
SLC26A1 -584
MAT2B -652
MTRR -681
GCLM -686
GLYATL1 -809
CYP4F2 -965
SULT1A2 -1072
GSTK1 -1403
FDX1 -1466
SULT2B1 -1553
POR -1559
NNMT -1626
UGT2A3 -1637
ABHD14B -1699
ACSS2 -1950
CYP26C1 -2129
UGT3A2 -2226
CYP1A2 -2361
GSS -2566
CYP4F8 -2568
PTGES3 -2688
NCOA2 -2737
AOC3 -2887
NAT2 -2929
GSTM3 -3014
ACY1 -3227
ADH1A -3246
ARNT -3292
ALDH1A1 -3380
CYP11B2 -3404
CYP3A7 -3439
GGT5 -3453
CES1 -3601
GSTM5 -3653
HSP90AB1 -3657
GSTM1 -3687
PAPSS2 -3763
CYP2F1 -3922
UGP2 -3924
CYP2S1 -3952
TPST1 -4213
ACSS1 -4258
MGST2 -4292
ADH1C -4300
CYP19A1 -4519
GSTM2 -4534
SULT6B1 -4616
RXRA -4727
GGT7 -4730
CYP11A1 -4753
FDX2 -4885
COMT -4908
GSTA2 -4941
ARNT2 -5025
CYP2U1 -5197
CYB5R3 -5227
AKR1A1 -5416
ACSM5 -5567
GSTZ1 -5699
MGST3 -5718
BPNT2 -5739
CYP2C19 -5754
UGT2B17 -5879
CYP2A7 -6005
SULT2A1 -6048
AOC1 -6090
UGT2B15 -6262
GGT1 -6273
DPEP3 -6585
PAPSS1 -6651
CYP2R1 -6920
SLC35B3 -6922
NQO2 -6970
POMC -7216
CYP46A1 -7387
PODXL2 -7618
PTGIS -7629
ALDH2 -7687
SMOX -7704
CNDP2 -7891
CYP3A43 -7917
FMO1 -7929
PAOX -8095
OPLAH -8167
TPST2 -8236
CYP1A1 -8325
CYP27A1 -8435
CYP4F3 -8569
UGDH -8677
GSTO1 -8736
AOC2 -8909
SLC35B2 -8980
ACY3 -9094
CYP2A13 -9121
PTGS1 -9216
DPEP1 -9396
GGT6 -9430
CYP4F22 -9681
SULT1C2 -9750
AIP -10004
CYP27B1 -10270
AADAC -10407
CYP3A5 -10759
SULT1E1 -11021
DPEP2 -11042


REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
78
set REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize 688
pANOVA 0.0148
s.dist -0.0545
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CSH1 -12081
UBA7 -12055
TNFSF14 -11987
CSF2 -11982
P4HB -11939
TNFRSF25 -11933
SIGIRR -11917
IL2 -11868
PSMB11 -11786
IL2RB -11759
IL13 -11717
POM121C -11669
IL3 -11646
CCL22 -11631
TNFRSF4 -11623
CSF3R -11619
CCL20 -11562
CD70 -11518

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111.0
CCL19 -12088.0
CSH1 -12081.0
UBA7 -12055.0
TNFSF14 -11987.0
CSF2 -11982.0
P4HB -11939.0
TNFRSF25 -11933.0
SIGIRR -11917.0
IL2 -11868.0
PSMB11 -11786.0
IL2RB -11759.0
IL13 -11717.0
POM121C -11669.0
IL3 -11646.0
CCL22 -11631.0
TNFRSF4 -11623.0
CSF3R -11619.0
CCL20 -11562.0
CD70 -11518.0
GH1 -11393.0
CSF1R -11340.0
PRKACA -11338.0
CD4 -11333.0
FCER2 -11330.0
PPP2CB -11323.0
PTPN11 -11265.0
TALDO1 -11242.0
CCL5 -11216.0
LIF -11067.0
SLA -11022.0
EIF4G1 -10986.0
IL17RE -10945.0
ISG15 -10915.0
CLCF1 -10904.0
GH2 -10880.0
TIFA -10834.0
VRK3 -10828.0
CTSG -10820.0
RELA -10818.0
NDN -10809.0
IL23A -10784.0
STX1A -10770.0
AGER -10754.0
NLRX1 -10737.0
TNFRSF6B -10726.0
SMAD3 -10719.0
IFNA14 -10712.0
IL18BP -10689.0
PSMB10 -10684.0
ITGB2 -10658.0
NOD2 -10630.0
TNFRSF1B -10604.0
SMARCA4 -10525.0
TRIM21 -10494.0
IFNB1 -10465.0
IL17A -10398.0
IFNA7 -10371.0
UBA3 -10315.0
IKBIP -10287.0
RAPGEF1 -10226.0
IL11RA -10225.0
ISG20 -10115.0
RIGI -10108.0
PTPN18 -10093.0
JAK1 -10086.0
IL27RA -10074.0
AIP -10004.0
IFI35 -9976.0
TRIM8 -9906.0
INPP5D -9904.0
TNFSF13B -9895.0
CTF1 -9873.0
RPS6KA1 -9870.0
PPP2R1A -9863.0
PSMD2 -9860.0
CIITA -9851.0
ITGB1 -9802.0
PSMD4 -9796.0
ELOB -9734.0
CSF2RB -9664.0
MAPK3 -9613.0
MAP2K3 -9582.0
CCL2 -9572.0
IFNAR2 -9533.0
ITGAX -9524.0
CSF3 -9485.0
PRKCD -9415.0
IL11 -9359.0
IL17RB -9326.0
RELB -9309.0
SNRPA1 -9295.0
NUP85 -9221.0
TOLLIP -9202.0
KPNA3 -9174.0
TNFSF12 -9162.0
LTBR -9072.0
IL4R -9070.0
TRIM45 -9044.0
PTGS2 -8943.0
RAG2 -8869.0
TNFRSF11A -8868.0
PIK3CD -8794.0
GBP3 -8758.0
UBE2L6 -8742.0
GSTO1 -8736.0
IFNG -8719.0
PSMB5 -8682.0
TRIM46 -8647.0
PRTN3 -8620.0
IL37 -8558.0
TAB1 -8507.0
H3C10 -8504.0
LCN2 -8386.0
IL10RB -8366.0
ICAM1 -8361.0
IFNGR2 -8356.0
IL19 -8336.0
PTPN1 -8324.0
SQSTM1 -8309.0
CXCL1 -8270.0
MAPKAPK3 -8261.0
IL1RL2 -8165.0
NUP58 -8136.0
PELI2 -8097.0
CSK -8088.0
HERC5 -8054.0
SRC -8020.0
TNFSF8 -8001.0
CAMK2B -7960.0
HSP90AA1 -7947.0
PTPN12 -7938.0
ALOX5 -7874.0
EIF4A1 -7868.0
TRIM10 -7859.0
CAMK2A -7857.0
ADAM17 -7843.0
TNIP2 -7794.0
NUP188 -7682.0
PSMA3 -7677.0
NUP35 -7652.0
GBP7 -7613.0
JUNB -7569.0
MT2A -7566.0
PSMD11 -7547.0
CXCL10 -7516.0
PSME4 -7486.0
PTPN6 -7453.0
SHC1 -7445.0
AKT1 -7424.0
GSDMD -7410.0
CNTFR -7399.0
NLRC5 -7393.0
IL17C -7385.0
STXBP2 -7334.0
AAAS -7333.0
TNFRSF12A -7329.0
EDARADD -7283.0
EBI3 -7279.0
PTK2B -7264.0
IFITM2 -7255.0
POMC -7216.0
TRAF3 -7207.0
SDC1 -7206.0
NUP62 -7204.0
VAV1 -7135.0
TEC -7088.0
CCL3 -7010.0
PSMA2 -6980.0
NUP210 -6939.0
IL27 -6881.0
PSMA1 -6876.0
MAPK1 -6855.0
CBL -6836.0
KPNA4 -6810.0
IRS2 -6743.0
SOX2 -6742.0
CASP8 -6741.0
TYK2 -6710.0
GBP4 -6670.0
H3C11 -6664.0
TRIM25 -6635.0
CISH -6618.0
HAVCR2 -6608.0
ARF1 -6582.0
JAK3 -6576.0
IL9 -6556.0
IL5 -6517.0
CREB1 -6475.0
RBX1 -6402.0
PSMA6 -6365.0
IL25 -6327.0
IL17RA -6265.0
IL36RN -6186.0
VIM -6141.0
IL1A -6115.0
HCK -6054.0
IFNAR1 -6022.0
PSMD12 -5986.0
SOD1 -5976.0
IFIT1 -5952.0
CRK -5923.0
STAT3 -5857.0
PIN1 -5856.0
ZEB1 -5846.0
SH2B1 -5843.0
HRAS -5842.0
XAF1 -5815.0
PLCG2 -5798.0
PIK3R2 -5785.0
IFIT5 -5765.0
CEBPD -5750.0
SOD2 -5729.0
LBP -5663.0
PIK3CB -5554.0
TXLNA -5551.0
HMOX1 -5508.0
TGFB1 -5470.0
IL15RA -5465.0
TNFRSF11B -5457.0
RPS27A -5429.0
TRAF2 -5377.0
NFKBIB -5367.0
MAP3K14 -5326.0
DUSP4 -5311.0
IL22RA2 -5304.0
PTPRZ1 -5218.0
NUP43 -5120.0
PSMC1 -5113.0
MMP2 -5095.0
FOXO1 -5027.0
CXCL8 -5015.0
IL22 -5008.0
NANOG -4956.0
PSMB7 -4950.0
GSTA2 -4941.0
IFITM3 -4907.0
TRIM3 -4900.0
TNFRSF1A -4881.0
LCK -4755.0
TP53 -4747.0
PSMC4 -4685.0
MCL1 -4678.0
GATA3 -4657.0
IRF5 -4557.0
IRF7 -4529.0
TRIM6 -4525.0
PSMC5 -4488.0
SUMO1 -4460.0
CRKL -4451.0
YES1 -4430.0
IL1R2 -4408.0
ATF2 -4363.0
IL1RL1 -4352.0
TRIM26 -4338.0
PSMA7 -4316.0
IKBKB -4264.0
NUP205 -4252.0
EIF4A3 -4249.0
TNFSF4 -4190.0
IFNA2 -4144.0
PIM1 -4139.0
CDKN1B -4124.0
LIFR -4107.0
STAT5A -4080.0
IL26 -4078.0
TNF -4077.0
CAMK2G -4058.0
ALPK1 -4027.0
NUP214 -4005.0
TRIM62 -3986.0
SH2B3 -3940.0
SLA2 -3915.0
ELOC -3906.0
NFKBIA -3895.0
PTAFR -3879.0
DUSP7 -3870.0
PTPN2 -3866.0
IFNL1 -3673.0
NKIRAS2 -3624.0
PIAS1 -3571.0
MAP2K4 -3534.0
SKP1 -3528.0
FASLG -3469.0
FLNB -3382.0
SMAD7 -3372.0
H3C2 -3371.0
BST2 -3352.0
FYN -3338.0
IFI30 -3314.0
PTPN13 -3278.0
CXCL2 -3269.0
STAT4 -3262.0
BCL6 -3253.0
PSMA8 -3243.0
RAG1 -3213.0
RPS6KA2 -3190.0
NUP93 -3168.0
IL16 -3139.0
MAPK9 -3136.0
CDKN1A -3108.0
PSME3 -3093.0
PTPN14 -3009.0
UBE2E1 -3000.0
INPPL1 -2996.0
IL20 -2948.0
ADAR -2876.0
UBE2D3 -2833.0
STAT6 -2813.0
PTPRJ -2804.0
TRIM35 -2758.0
POU2F1 -2708.0
NUP155 -2674.0
N4BP1 -2658.0
HLA-H -2592.0
PSMD1 -2565.0
PSMD5 -2542.0
EGR1 -2536.0
IRF8 -2509.0
UBA52 -2492.0
TNFSF9 -2490.0
PSMA5 -2478.0
FBXW11 -2475.0
IL1R1 -2452.0
TRIM14 -2425.0
BCL2L11 -2398.0
MYD88 -2385.0
LCP1 -2283.0
PSMA4 -2277.0
IL6R -2236.0
DUSP3 -2222.0
SNAP25 -2201.0
HLA-DRB1 -2165.0
TNFRSF8 -2138.0
NUP88 -2111.0
IP6K2 -2100.0
MAP3K7 -2087.0
IFNA6 -2082.0
AKT3 -2061.0
RHOU -2055.0
MAPK7 -2048.0
TAB2 -2014.0
S1PR1 -1998.0
PML -1989.0
IRF2 -1941.0
UBC -1940.0
LTB -1920.0
HSP90B1 -1787.0
PRL -1754.0
LTA -1751.0
KPNA5 -1709.0
RNF7 -1550.0
GBP2 -1537.0
IL24 -1529.0
PSME2 -1494.0
HIF1A -1395.0
HNRNPA2B1 -1390.0
POM121 -1311.0
SP100 -1232.0
PSMC2 -1220.0
IRF3 -1201.0
H3C8 -1195.0
BTRC -1184.0
MMP9 -1143.0
MAPK8 -1052.0
MUC1 -1026.0
EIF4G2 -1017.0
OSMR -1014.0
IL6ST -940.0
TRIM34 -935.0
EIF2AK2 -920.0
LGALS9 -880.0
IFNA5 -846.0
CD36 -823.0
ABCE1 -796.0
HLA-DQB1 -747.0
RPS6KA5 -719.0
IFNGR1 -696.0
STX4 -692.0
CAMK2D -669.0
RPLP0 -664.0
PTPN23 -663.0
PTPN5 -631.0
HLA-DRB5 -623.0
KRAS -603.0
HLA-E -574.0
ARIH1 -554.0
PRLR -452.0
TWIST1 -448.0
OASL -440.0
OAS2 -425.0
STX3 -406.0
BCL2 -384.0
CD80 -371.0
COL1A2 -317.0
SOCS6 -305.0
RNASEL -300.0
TRIM22 -286.0
HSPA8 -277.0
IRF9 -274.0
MAP2K7 -270.0
CA1 -263.0
LMNB1 -257.0
PSMB1 -252.0
RSAD2 -248.0
UBB -227.0
TNFSF11 -222.0
PTPN7 -176.0
PSMD6 -164.0
CNN2 -163.0
IL20RB -153.0
IRAK3 -118.0
H3C7 -18.5
HLA-DPB1 -11.0
CANX 15.0
HNRNPDL 43.0
IRS1 156.0
UBE2D2 201.0
NUP98 205.0
MEF2A 237.0
FOXO3 270.0
DUSP6 337.0
FN1 348.0
GHR 367.0
IL21 387.0
IRAK4 414.0
IRAK2 488.0
TNFRSF17 534.0
NUP50 587.0
IL1RN 644.0
MAP2K6 645.0
KPNA2 646.0
APP 650.0
IL6 738.0
TRIM68 752.0
TNFRSF13B 754.0
LAMA5 766.0
F13A1 804.0
CD40 841.0
BIRC2 852.0
BRWD1 855.0
MYC 885.0
CUL5 961.0
MIF 1011.0
MAPK10 1026.0
IL12RB1 1041.0
OAS1 1076.0
PIK3R3 1089.0
SOCS2 1098.0
EIF4E3 1105.0
RAP1B 1146.0
IL12A 1254.0
LYN 1258.0
TRIM17 1268.0
IL31 1274.0
RORA 1289.0
GAB2 1303.0
TRIM38 1324.0
NUP42 1333.0
RAE1 1336.0
PAK2 1378.0
IL10RA 1392.0
IL18R1 1458.0
FSCN1 1535.0
ABL2 1549.0
SEH1L 1557.0
UBE2N 1694.0
NUP133 1754.0
PLCG1 1779.0
PTPN4 1782.0
PSMB4 1792.0
CAPZA1 1811.0
ATF1 1815.0
PSMD7 1876.0
BATF 1900.0
UBE2V1 1909.0
IFI27 1945.0
CASP1 1950.0
IL17RC 2001.0
MAPKAPK2 2008.0
PSMD13 2068.0
HLA-G 2147.0
HNRNPF 2153.0
HLA-DQB2 2168.0
SYK 2191.0
PELI1 2226.0
NFKB1 2237.0
PIK3CA 2278.0
IRF6 2281.0
CHUK 2303.0
MX2 2330.0
ALOX15 2339.0
MAPK14 2381.0
NOS2 2391.0
IL31RA 2439.0
PPP2R5D 2473.0
MMP3 2498.0
FLT3LG 2499.0
PSMC6 2503.0
AKT2 2580.0
TNFRSF9 2597.0
FGF2 2607.0
CCND1 2617.0
PDCD4 2628.0
HSPA9 2638.0
IL15 2651.0
IFNLR1 2715.0
SOCS5 2719.0
IL36A 2752.0
STAT5B 2810.0
SEM1 2813.0
MAP3K8 2905.0
PPP2R1B 2955.0
PSMB2 3025.0
PSMB9 3120.0
TPR 3148.0
PSMF1 3165.0
BLNK 3179.0
H3C4 3221.0
NFKB2 3228.0
SOCS1 3250.0
NCAM1 3274.0
PSMD8 3281.0
GRB2 3310.0
HLA-C 3383.0
PSMD3 3393.0
TRAF6 3503.0
NUP153 3504.0
TRIM2 3570.0
CD44 3576.0
CRLF1 3646.0
IL1F10 3707.0
TRIM29 3722.0
PIK3R1 3776.0
CD27 3819.0
SOS2 3884.0
CASP3 3960.0
PPM1B 4032.0
IL17F 4147.0
PSMD9 4183.0
B2M 4202.0
IL18 4237.0
CDC42 4288.0
SOCS3 4305.0
HLA-DPA1 4322.0
HLA-DQA1 4357.0
KPNA1 4381.0
IL7 4408.0
ANXA1 4428.0
MTAP 4436.0
PSMD14 4464.0
NUP37 4483.0
TRIM31 4498.0
RANBP2 4543.0
NUP160 4564.0
CNTF 4575.0
SOS1 4593.0
ITGAM 4609.0
STAT2 4617.0
IL32 4630.0
IL12RB2 4690.0
YWHAZ 4708.0
CSF1 4725.0
CD86 4756.0
EIF4A2 4824.0
EIF4E2 4836.0
IL34 4864.0
MAP2K1 4867.0
HLA-A 4880.0
GRB10 4895.0
HLA-DRA 4923.0
CCR5 4925.0
TCP1 4954.0
UBE2D1 4987.0
STAT1 5051.0
PPP2CA 5054.0
CCR2 5061.0
ANXA2 5158.0
BCL2L1 5179.0
KPNA7 5202.0
SERPINB2 5278.0
MEF2C 5339.0
FOS 5355.0
IFITM1 5378.0
IL2RA 5396.0
MX1 5409.0
IL12B 5429.0
KPNB1 5625.0
IRF4 5660.0
IL7R 5674.0
NKIRAS1 5746.0
CUL1 5793.0
NDC1 5901.0
THOC5 5940.0
IL1RAP 6012.0
PSME1 6143.0
EIF4G3 6171.0
PPIA 6172.0
BIRC5 6196.0
VEGFA 6207.0
IL21R 6229.0
IL18RAP 6234.0
RORC 6241.0
OPRM1 6259.0
PSMB8 6298.0
NRAS 6299.0
IFIT2 6309.0
MAP3K3 6367.0
TNFRSF18 6487.0
GBP1 6518.0
VCAM1 6567.0
UBE2M 6580.0
CFL1 6601.0
LRRC14 6693.0
PITPNA 6702.0
TNFSF15 6723.0
JUN 6753.0
S100B 6783.0
IL23R 6793.0
SAA1 6821.0
OAS3 6870.0
PSMC3 6871.0
GRAP2 6881.0
H3C6 6884.0
PSMB3 6898.0
TRIM5 6928.0
FLT3 6941.0
IFNA8 6945.0
GBP6 6983.0
TBK1 6986.0
VAMP2 7018.0
JAK2 7072.0
NEDD4 7140.0
NOD1 7172.0
HLA-DQA2 7198.0
PSMB6 7376.0
IL33 7385.0
HMGB1 7457.0
IFI6 7498.0
RIPK2 7515.0
PIK3CG 7520.0
SAMHD1 7567.0
TSLP 7596.0
SEC13 7609.0
IFIT3 7636.0
BIRC3 7655.0
USP14 7708.0
NUP54 7715.0
EIF4E 7738.0
OSM 7791.0
IRF1 7826.0
PTPN9 7874.0
IL20RA 7950.0
IL36G 8076.0
USP18 8153.0
IL22RA1 8166.0
CCL11 8186.0
PELI3 8194.0
PDE12 8218.0
RALA 8296.0
HGF 8325.0
EDAR 8364.0
OPRD1 8483.0
MAPK11 8514.0
NUP107 8524.0
IFNA13 8579.0
HLA-B 8651.0
IL36B 8660.0
TNFSF18 8672.0
IL5RA 8675.0
H3C3 8781.0
H3C1 9006.0
MMP1 9036.0
CCR1 9046.0
HLA-F 9053.0
S100A12 9057.0
IFNA1 9314.0
GBP5 9349.0
H3C12 9387.0
IFNA16 9463.0
TNFSF13 9472.0
IFNL2 9499.0
IL10 9516.0
IL4 9580.0
IL1B 9587.0
FPR1 9622.0
TNFRSF13C 9671.0
IFNA21 9792.0


REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS
800
set REACTOME_SIGNALING_BY_INTERLEUKINS
setSize 444
pANOVA 0.0148
s.dist -0.0674
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL4 -12111
CCL19 -12088
CSF2 -11982
P4HB -11939
SIGIRR -11917
IL2 -11868
PSMB11 -11786
IL2RB -11759
IL13 -11717
IL3 -11646
CCL22 -11631
CSF3R -11619
CCL20 -11562
CSF1R -11340
PRKACA -11338
CD4 -11333
FCER2 -11330
PPP2CB -11323
PTPN11 -11265
TALDO1 -11242

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL4 -12111.0
CCL19 -12088.0
CSF2 -11982.0
P4HB -11939.0
SIGIRR -11917.0
IL2 -11868.0
PSMB11 -11786.0
IL2RB -11759.0
IL13 -11717.0
IL3 -11646.0
CCL22 -11631.0
CSF3R -11619.0
CCL20 -11562.0
CSF1R -11340.0
PRKACA -11338.0
CD4 -11333.0
FCER2 -11330.0
PPP2CB -11323.0
PTPN11 -11265.0
TALDO1 -11242.0
CCL5 -11216.0
LIF -11067.0
IL17RE -10945.0
CLCF1 -10904.0
TIFA -10834.0
VRK3 -10828.0
CTSG -10820.0
RELA -10818.0
NDN -10809.0
IL23A -10784.0
STX1A -10770.0
AGER -10754.0
NLRX1 -10737.0
SMAD3 -10719.0
IL18BP -10689.0
PSMB10 -10684.0
ITGB2 -10658.0
NOD2 -10630.0
TNFRSF1B -10604.0
SMARCA4 -10525.0
IL17A -10398.0
IKBIP -10287.0
RAPGEF1 -10226.0
IL11RA -10225.0
PTPN18 -10093.0
JAK1 -10086.0
IL27RA -10074.0
AIP -10004.0
INPP5D -9904.0
CTF1 -9873.0
RPS6KA1 -9870.0
PPP2R1A -9863.0
PSMD2 -9860.0
ITGB1 -9802.0
PSMD4 -9796.0
CSF2RB -9664.0
MAPK3 -9613.0
MAP2K3 -9582.0
CCL2 -9572.0
ITGAX -9524.0
CSF3 -9485.0
IL11 -9359.0
IL17RB -9326.0
SNRPA1 -9295.0
TOLLIP -9202.0
IL4R -9070.0
PTGS2 -8943.0
RAG2 -8869.0
PIK3CD -8794.0
GSTO1 -8736.0
IFNG -8719.0
PSMB5 -8682.0
PRTN3 -8620.0
IL37 -8558.0
TAB1 -8507.0
H3C10 -8504.0
LCN2 -8386.0
IL10RB -8366.0
ICAM1 -8361.0
IL19 -8336.0
SQSTM1 -8309.0
CXCL1 -8270.0
MAPKAPK3 -8261.0
IL1RL2 -8165.0
PELI2 -8097.0
HSP90AA1 -7947.0
PTPN12 -7938.0
ALOX5 -7874.0
TNIP2 -7794.0
PSMA3 -7677.0
JUNB -7569.0
PSMD11 -7547.0
CXCL10 -7516.0
PSME4 -7486.0
PTPN6 -7453.0
SHC1 -7445.0
AKT1 -7424.0
GSDMD -7410.0
CNTFR -7399.0
NLRC5 -7393.0
IL17C -7385.0
STXBP2 -7334.0
EBI3 -7279.0
PTK2B -7264.0
POMC -7216.0
SDC1 -7206.0
VAV1 -7135.0
TEC -7088.0
CCL3 -7010.0
PSMA2 -6980.0
IL27 -6881.0
PSMA1 -6876.0
MAPK1 -6855.0
CBL -6836.0
IRS2 -6743.0
SOX2 -6742.0
CASP8 -6741.0
TYK2 -6710.0
H3C11 -6664.0
CISH -6618.0
HAVCR2 -6608.0
ARF1 -6582.0
JAK3 -6576.0
IL9 -6556.0
IL5 -6517.0
CREB1 -6475.0
RBX1 -6402.0
PSMA6 -6365.0
IL25 -6327.0
IL17RA -6265.0
IL36RN -6186.0
VIM -6141.0
IL1A -6115.0
HCK -6054.0
PSMD12 -5986.0
SOD1 -5976.0
CRK -5923.0
STAT3 -5857.0
ZEB1 -5846.0
PIK3R2 -5785.0
CEBPD -5750.0
SOD2 -5729.0
LBP -5663.0
PIK3CB -5554.0
TXLNA -5551.0
HMOX1 -5508.0
TGFB1 -5470.0
IL15RA -5465.0
RPS27A -5429.0
TRAF2 -5377.0
NFKBIB -5367.0
DUSP4 -5311.0
IL22RA2 -5304.0
PTPRZ1 -5218.0
PSMC1 -5113.0
MMP2 -5095.0
FOXO1 -5027.0
CXCL8 -5015.0
IL22 -5008.0
NANOG -4956.0
PSMB7 -4950.0
GSTA2 -4941.0
TNFRSF1A -4881.0
LCK -4755.0
TP53 -4747.0
PSMC4 -4685.0
MCL1 -4678.0
GATA3 -4657.0
PSMC5 -4488.0
CRKL -4451.0
YES1 -4430.0
IL1R2 -4408.0
ATF2 -4363.0
IL1RL1 -4352.0
PSMA7 -4316.0
IKBKB -4264.0
PIM1 -4139.0
LIFR -4107.0
STAT5A -4080.0
IL26 -4078.0
TNF -4077.0
ALPK1 -4027.0
NFKBIA -3895.0
PTAFR -3879.0
DUSP7 -3870.0
PTPN2 -3866.0
IFNL1 -3673.0
NKIRAS2 -3624.0
MAP2K4 -3534.0
SKP1 -3528.0
FASLG -3469.0
H3C2 -3371.0
FYN -3338.0
PTPN13 -3278.0
CXCL2 -3269.0
STAT4 -3262.0
BCL6 -3253.0
PSMA8 -3243.0
RAG1 -3213.0
RPS6KA2 -3190.0
IL16 -3139.0
MAPK9 -3136.0
CDKN1A -3108.0
PSME3 -3093.0
PTPN14 -3009.0
INPPL1 -2996.0
IL20 -2948.0
STAT6 -2813.0
POU2F1 -2708.0
N4BP1 -2658.0
PSMD1 -2565.0
PSMD5 -2542.0
UBA52 -2492.0
PSMA5 -2478.0
FBXW11 -2475.0
IL1R1 -2452.0
MYD88 -2385.0
LCP1 -2283.0
PSMA4 -2277.0
IL6R -2236.0
DUSP3 -2222.0
SNAP25 -2201.0
MAP3K7 -2087.0
RHOU -2055.0
MAPK7 -2048.0
TAB2 -2014.0
S1PR1 -1998.0
UBC -1940.0
HSP90B1 -1787.0
IL24 -1529.0
PSME2 -1494.0
HIF1A -1395.0
HNRNPA2B1 -1390.0
PSMC2 -1220.0
H3C8 -1195.0
BTRC -1184.0
MMP9 -1143.0
MAPK8 -1052.0
MUC1 -1026.0
OSMR -1014.0
IL6ST -940.0
LGALS9 -880.0
CD36 -823.0
RPS6KA5 -719.0
STX4 -692.0
RPLP0 -664.0
PTPN23 -663.0
PTPN5 -631.0
TWIST1 -448.0
STX3 -406.0
BCL2 -384.0
CD80 -371.0
COL1A2 -317.0
HSPA8 -277.0
MAP2K7 -270.0
CA1 -263.0
LMNB1 -257.0
PSMB1 -252.0
UBB -227.0
PTPN7 -176.0
PSMD6 -164.0
CNN2 -163.0
IL20RB -153.0
IRAK3 -118.0
H3C7 -18.5
CANX 15.0
HNRNPDL 43.0
IRS1 156.0
MEF2A 237.0
FOXO3 270.0
DUSP6 337.0
FN1 348.0
IL21 387.0
IRAK4 414.0
IRAK2 488.0
IL1RN 644.0
MAP2K6 645.0
APP 650.0
IL6 738.0
LAMA5 766.0
F13A1 804.0
BRWD1 855.0
MYC 885.0
MIF 1011.0
MAPK10 1026.0
IL12RB1 1041.0
PIK3R3 1089.0
SOCS2 1098.0
RAP1B 1146.0
IL12A 1254.0
LYN 1258.0
IL31 1274.0
RORA 1289.0
GAB2 1303.0
PAK2 1378.0
IL10RA 1392.0
IL18R1 1458.0
FSCN1 1535.0
UBE2N 1694.0
PTPN4 1782.0
PSMB4 1792.0
CAPZA1 1811.0
ATF1 1815.0
PSMD7 1876.0
BATF 1900.0
UBE2V1 1909.0
CASP1 1950.0
IL17RC 2001.0
MAPKAPK2 2008.0
PSMD13 2068.0
HNRNPF 2153.0
SYK 2191.0
PELI1 2226.0
NFKB1 2237.0
PIK3CA 2278.0
CHUK 2303.0
ALOX15 2339.0
MAPK14 2381.0
NOS2 2391.0
IL31RA 2439.0
PPP2R5D 2473.0
MMP3 2498.0
PSMC6 2503.0
FGF2 2607.0
CCND1 2617.0
PDCD4 2628.0
HSPA9 2638.0
IL15 2651.0
IFNLR1 2715.0
SOCS5 2719.0
IL36A 2752.0
STAT5B 2810.0
SEM1 2813.0
MAP3K8 2905.0
PPP2R1B 2955.0
PSMB2 3025.0
PSMB9 3120.0
PSMF1 3165.0
BLNK 3179.0
H3C4 3221.0
NFKB2 3228.0
SOCS1 3250.0
PSMD8 3281.0
GRB2 3310.0
PSMD3 3393.0
TRAF6 3503.0
CRLF1 3646.0
IL1F10 3707.0
PIK3R1 3776.0
SOS2 3884.0
CASP3 3960.0
IL17F 4147.0
PSMD9 4183.0
IL18 4237.0
CDC42 4288.0
SOCS3 4305.0
IL7 4408.0
ANXA1 4428.0
MTAP 4436.0
PSMD14 4464.0
CNTF 4575.0
SOS1 4593.0
ITGAM 4609.0
STAT2 4617.0
IL32 4630.0
IL12RB2 4690.0
YWHAZ 4708.0
CSF1 4725.0
CD86 4756.0
IL34 4864.0
MAP2K1 4867.0
CCR5 4925.0
TCP1 4954.0
STAT1 5051.0
PPP2CA 5054.0
CCR2 5061.0
ANXA2 5158.0
BCL2L1 5179.0
SERPINB2 5278.0
MEF2C 5339.0
FOS 5355.0
IL2RA 5396.0
IL12B 5429.0
IRF4 5660.0
IL7R 5674.0
NKIRAS1 5746.0
CUL1 5793.0
IL1RAP 6012.0
PSME1 6143.0
PPIA 6172.0
BIRC5 6196.0
VEGFA 6207.0
IL21R 6229.0
IL18RAP 6234.0
RORC 6241.0
OPRM1 6259.0
PSMB8 6298.0
MAP3K3 6367.0
VCAM1 6567.0
CFL1 6601.0
LRRC14 6693.0
PITPNA 6702.0
JUN 6753.0
S100B 6783.0
IL23R 6793.0
SAA1 6821.0
PSMC3 6871.0
H3C6 6884.0
PSMB3 6898.0
TBK1 6986.0
VAMP2 7018.0
JAK2 7072.0
NOD1 7172.0
PSMB6 7376.0
IL33 7385.0
HMGB1 7457.0
RIPK2 7515.0
TSLP 7596.0
USP14 7708.0
OSM 7791.0
PTPN9 7874.0
IL20RA 7950.0
IL36G 8076.0
USP18 8153.0
IL22RA1 8166.0
CCL11 8186.0
PELI3 8194.0
RALA 8296.0
HGF 8325.0
OPRD1 8483.0
MAPK11 8514.0
IL36B 8660.0
IL5RA 8675.0
H3C3 8781.0
H3C1 9006.0
MMP1 9036.0
CCR1 9046.0
S100A12 9057.0
H3C12 9387.0
IFNL2 9499.0
IL10 9516.0
IL4 9580.0
IL1B 9587.0
FPR1 9622.0


REACTOME_GPER1_SIGNALING

REACTOME_GPER1_SIGNALING
1488
set REACTOME_GPER1_SIGNALING
setSize 45
pANOVA 0.015
s.dist -0.21
p.adjustANOVA 0.546



Top enriched genes

Top 20 genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
PRKACA -11338
GNG3 -10992
ADCY4 -10769
GNAI2 -10681
ITGB1 -9802
GNB1 -9556
ADCY1 -9465
GNAI3 -8894
PRKAR1A -8804
GNAS -8327
SRC -8020
GPER1 -7976
GNG5 -7692
SHC1 -7445
GNG4 -7396
GNG10 -6722
PRKACG -6681
GNGT2 -6044

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ADCY7 -11853
GNG11 -11464
PRKACA -11338
GNG3 -10992
ADCY4 -10769
GNAI2 -10681
ITGB1 -9802
GNB1 -9556
ADCY1 -9465
GNAI3 -8894
PRKAR1A -8804
GNAS -8327
SRC -8020
GPER1 -7976
GNG5 -7692
SHC1 -7445
GNG4 -7396
GNG10 -6722
PRKACG -6681
GNGT2 -6044
PRKAR2A -5493
GNB5 -5001
GNG2 -4850
GNG7 -4167
GNAI1 -4123
ADCY5 -4086
PRKAR2B -2679
ADCY3 -2066
GNB4 -853
ADCY2 -724
FN1 348
GNAZ 555
GNAT3 2081
ADCY9 2128
ADCY6 2694
GNB3 2797
GNB2 2815
PRKAR1B 3155
GNG8 3600
ITGA5 3682
ADCY8 4687
PRKACB 6173
GNG12 6818
GNG13 8304
GNGT1 9233


REACTOME_PHOSPHOLIPID_METABOLISM

REACTOME_PHOSPHOLIPID_METABOLISM
136
set REACTOME_PHOSPHOLIPID_METABOLISM
setSize 201
pANOVA 0.0162
s.dist -0.0984
p.adjustANOVA 0.567



Top enriched genes

Top 20 genes
GeneID Gene Rank
TPTE -11894
GPAT2 -11818
PNPLA2 -11636
PLA1A -11462
GPD1 -11452
TNFAIP8L1 -11435
LPCAT4 -11321
PISD -11275
LIPH -11182
PLA2G4F -11155
CHKB -11147
DGAT2 -10859
DGAT1 -10797
ETNPPL -10744
AGPAT2 -10656
PLA2G2E -10460
PTPMT1 -10431
LPIN2 -10274
PLA2G15 -10261
GPD2 -10056

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TPTE -11894
GPAT2 -11818
PNPLA2 -11636
PLA1A -11462
GPD1 -11452
TNFAIP8L1 -11435
LPCAT4 -11321
PISD -11275
LIPH -11182
PLA2G4F -11155
CHKB -11147
DGAT2 -10859
DGAT1 -10797
ETNPPL -10744
AGPAT2 -10656
PLA2G2E -10460
PTPMT1 -10431
LPIN2 -10274
PLA2G15 -10261
GPD2 -10056
SYNJ2 -9931
INPP5D -9904
PGS1 -9677
PIP5K1A -9675
PLD6 -9259
PLD1 -9056
PLA2G4B -8938
PCYT2 -8871
PIK3CD -8794
PIK3C2B -8718
PLA2G4E -8627
INPP4A -8564
INPP5F -8195
CRLS1 -8190
GDPD3 -8140
CPNE6 -8094
PI4K2B -7993
PIK3R4 -7954
AGPAT5 -7860
SELENOI -7833
PLA2G4D -7754
ARF3 -7715
PLA2G2D -7660
PLAAT5 -7521
GPD1L -7303
CSNK2A1 -7248
PITPNM1 -7247
PIK3R5 -7226
LPCAT1 -7123
MTMR9 -7108
PITPNB -7106
CSNK2A2 -7081
FIG4 -6797
MTMR4 -6769
MFSD2A -6749
MBOAT2 -6619
ABHD4 -6617
ARF1 -6582
PLD3 -6532
PNPLA3 -6527
ETNK2 -6495
CHKA -6426
PLEKHA2 -6412
TNFAIP8 -6318
OSBPL5 -6283
CPNE3 -6252
PI4KB -6240
SBF1 -6080
PLA2G12A -6016
PIP5K1C -5908
PIK3R2 -5785
RAB5A -5749
PLEKHA3 -5684
AGK -5636
PIK3CB -5554
STARD10 -5492
HADHA -5459
AGPAT3 -5372
LPGAT1 -5193
CHAT -5128
PLD2 -5102
SLC44A4 -4933
TMEM86B -4899
CPNE7 -4876
GPAT4 -4828
PLEKHA4 -4745
PTEN -4735
CDS1 -4641
MGLL -4627
PLEKHA6 -4582
MTMR14 -4485
PI4K2A -4453
LPCAT2 -4371
PIKFYVE -4305
PLAAT3 -4166
PLAAT1 -4074
RAB14 -3750
PLEKHA8 -3736
PLBD1 -3626
PTPN13 -3278
CPNE1 -3248
PIK3C3 -3232
PITPNM2 -3203
PNPLA7 -3020
PEMT -3015
INPPL1 -2996
PIK3R6 -2969
PLEKHA1 -2866
AGPAT1 -2820
CDS2 -2550
PNPLA6 -2479
MIGA2 -2466
INPP4B -1874
SLC44A1 -1653
MTMR3 -1614
PLA2R1 -1581
CSNK2B -1517
MTMR7 -1191
INPP5E -1045
MBOAT1 -943
GDPD5 -924
MTMR6 -918
LPIN3 -609
PCYT1A -571
ALPI -547
PLA2G4C -333
PNPLA8 -258
ACHE 47
SACM1L 69
RAB4A 152
SLC44A2 265
CHPT1 300
MIGA1 323
PITPNM3 368
PLA2G6 882
PIK3R3 1089
PI4KA 1111
GDPD1 1162
GDE1 1288
PLA2G4A 1299
PTDSS2 1394
OSBPL10 1566
TNFAIP8L3 1765
PLAAT4 2000
DDHD1 2118
CEPT1 2126
PIK3CA 2278
LPIN1 2507
HADHB 2515
LPCAT3 2666
PLA2G3 2861
PLB1 2966
AGPAT4 3080
PLD4 3510
CDIPT 3663
PIK3R1 3776
SBF2 3930
VAC14 4096
MBOAT7 4126
ENPP6 4145
OSBPL8 4160
SYNJ1 4474
PIP4P1 4650
GNPAT 4734
PLA2G1B 4991
RUFY1 5144
PIK3C2A 5650
PIP5K1B 5694
SLC44A5 5946
PIP4K2B 5977
PCTP 6009
PLEKHA5 6051
MTMR12 6094
GPAM 6195
PTDSS1 6278
ETNK1 6302
MTMR2 6439
PIP4K2A 6490
PLA2G2A 6493
SLC44A3 6507
ABHD3 6772
TPTE2 6792
PIK3C2G 6910
TNFAIP8L2 7029
INPP5J 7313
INPP5K 7430
GPCPD1 7445
PIK3CG 7520
PLA2G5 7529
LCLAT1 8125
MTMR10 8152
PHOSPHO1 8157
ACP6 8277
DDHD2 8341
STARD7 8379
PIP4K2C 8382
PLAAT2 8623
BCHE 8810
PLA2G10 8967
LIPI 9009
PLA2G2F 9556


REACTOME_INSULIN_RECEPTOR_RECYCLING

REACTOME_INSULIN_RECEPTOR_RECYCLING
1207
set REACTOME_INSULIN_RECEPTOR_RECYCLING
setSize 29
pANOVA 0.0163
s.dist -0.258
p.adjustANOVA 0.567



Top enriched genes

Top 20 genes
GeneID Gene Rank
CTSD -11960
ATP6V1E2 -11469
ATP6V0C -11115
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
ATP6V0A1 -9864
ATP6V1E1 -9547
ATP6V0B -9464
ATP6V1C2 -8680
PTPN1 -8324
ATP6V0A2 -8252
ATP6V1C1 -7442
INSR -5912
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
PTPRF -2979
IDE -2203
ATP6V1G3 -1735

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CTSD -11960
ATP6V1E2 -11469
ATP6V0C -11115
ATP6V1B2 -10690
ATP6V0E1 -10257
ATP6V0D1 -10139
ATP6V0A1 -9864
ATP6V1E1 -9547
ATP6V0B -9464
ATP6V1C2 -8680
PTPN1 -8324
ATP6V0A2 -8252
ATP6V1C1 -7442
INSR -5912
ATP6V1H -4599
ATP6V0E2 -4165
ATP6V1G2 -3667
PTPRF -2979
IDE -2203
ATP6V1G3 -1735
ATP6V1F 288
TCIRG1 669
ATP6V0A4 1648
ATP6V1B1 1697
ATP6V1G1 3618
ATP6V1A 5106
ATP6V1D 5637
ATP6V0D2 9100
INS 9527


REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING

REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING
1447
set REACTOME_NEGATIVE_REGULATORS_OF_DDX58_IFIH1_SIGNALING
setSize 34
pANOVA 0.0169
s.dist -0.237
p.adjustANOVA 0.567



Top enriched genes

Top 20 genes
GeneID Gene Rank
UBA7 -12055
ISG15 -10915
NLRX1 -10737
RNF135 -10732
TRIM4 -10687
RIGI -10108
UBE2L6 -8742
RNF125 -8436
IKBKE -8379
HERC5 -8054
RNF216 -7990
NLRC5 -7393
TRAF3 -7207
CYLD -6869
TRIM25 -6635
PIN1 -5856
RPS27A -5429
UBE2D3 -2833
UBA52 -2492
UBC -1940

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
UBA7 -12055
ISG15 -10915
NLRX1 -10737
RNF135 -10732
TRIM4 -10687
RIGI -10108
UBE2L6 -8742
RNF125 -8436
IKBKE -8379
HERC5 -8054
RNF216 -7990
NLRC5 -7393
TRAF3 -7207
CYLD -6869
TRIM25 -6635
PIN1 -5856
RPS27A -5429
UBE2D3 -2833
UBA52 -2492
UBC -1940
IRF3 -1201
TNFAIP3 -931
MAVS -864
PCBP2 -709
TAX1BP1 -701
UBB -227
UBE2D2 201
UBE2K 382
ATG5 815
ATG12 3426
UBE2D1 4987
ITCH 5644
TBK1 6986
IFIH1 8530


REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING
771
set REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING
setSize 25
pANOVA 0.0173
s.dist -0.275
p.adjustANOVA 0.567



Top enriched genes

Top 20 genes
GeneID Gene Rank
GRIN2D -11507
RPS6KA1 -9870
MAPK3 -9613
GRIN1 -9343
PDPK1 -9058
NEFL -8843
RASGRF1 -7965
CAMK2B -7960
CAMK2A -7857
MAPK1 -6855
CREB1 -6475
HRAS -5842
DLG4 -4975
CAMK2G -4058
ACTN2 -3775
RPS6KA2 -3190
CALM1 -2218
GRIN2B -1824
CAMK2D -669
KRAS -603

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GRIN2D -11507
RPS6KA1 -9870
MAPK3 -9613
GRIN1 -9343
PDPK1 -9058
NEFL -8843
RASGRF1 -7965
CAMK2B -7960
CAMK2A -7857
MAPK1 -6855
CREB1 -6475
HRAS -5842
DLG4 -4975
CAMK2G -4058
ACTN2 -3775
RPS6KA2 -3190
CALM1 -2218
GRIN2B -1824
CAMK2D -669
KRAS -603
RASGRF2 1522
DLG1 2122
DLG2 4058
LRRC7 4420
NRAS 6299


REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION

REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
737
set REACTOME_SIRT1_NEGATIVELY_REGULATES_RRNA_EXPRESSION
setSize 60
pANOVA 0.0177
s.dist 0.177
p.adjustANOVA 0.567



Top enriched genes

Top 20 genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
H2AX 7192.0
H3C6 6884.0
RRP8 6799.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
H2AC14 9535.0
H3C12 9387.0
H2AC18 9323.5
H2AC19 9323.5
H2BC3 9018.0
H3C1 9006.0
H2BC6 8802.0
H3C3 8781.0
H4C1 8144.0
H2BC17 7929.0
H2AC4 7772.0
H4C8 7688.0
H2AX 7192.0
H3C6 6884.0
RRP8 6799.0
H4C5 6673.0
H4C6 6591.0
H2BC14 6122.0
H2AZ2 6053.0
H4C4 5750.0
H3-3A 5167.0
H4C12 4671.0
H2BC11 4341.0
TBP 3787.0
H3C4 3221.0
H4C3 2803.0
H2AC7 2726.5
H2BC7 2726.5
TAF1A 2457.0
H2BC12 1426.0
H2BC5 741.0
H4C16 326.0
H2BC9 -18.5
H3C7 -18.5
H4C9 -77.0
H2AZ1 -219.0
H3C8 -1195.0
H2BC4 -1847.0
TAF1D -1955.0
H2AC6 -2387.0
H3C2 -3371.0
H2BC26 -3442.0
TAF1B -3793.0
SIRT1 -4307.0
H2BC1 -4333.0
H4C13 -4551.0
H2AC8 -5188.0
H4C11 -5525.0
H2BC13 -5652.0
H3-3B -6496.0
H3C11 -6664.0
H2AC20 -8295.0
H2BC21 -8370.0
H2BC10 -8462.0
H3C10 -8504.0
H2AJ -8875.0
H4C2 -9517.0
H2BC8 -9562.0
H2BC15 -9905.0
TAF1C -10491.0


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report