Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0022820
A1BG-AS1	0.0043776
A1CF	0.0083460
A2M	0.0010142
A2M-AS1	0.0054034
A2ML1	0.0022550

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
## https://haozhu233.github.io/kableExtra/ for details.

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME METABOLISM OF RNA	675	5.37e-07	0.1130	0.000882
REACTOME TRANSLATION	278	2.07e-06	0.1650	0.001700
REACTOME INFLUENZA INFECTION	149	6.00e-06	0.2150	0.003280
REACTOME NEUTROPHIL DEGRANULATION	460	9.03e-06	0.1210	0.003710
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.40e-05	0.2430	0.004200
REACTOME ASPIRIN ADME	42	1.54e-05	0.3850	0.004200
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	1.90e-05	0.2360	0.004470
REACTOME SNRNP ASSEMBLY	53	5.11e-05	0.3220	0.009640
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.28e-05	0.2510	0.009640
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.42e-05	0.2240	0.012000
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	8.73e-05	0.3340	0.012000
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	8.75e-05	-0.4940	0.012000
REACTOME FATTY ACIDS	15	9.97e-05	0.5800	0.012600
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.35e-04	0.1820	0.015800
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	2.14e-04	-0.3340	0.023400
REACTOME NEURONAL SYSTEM	388	3.47e-04	-0.1060	0.034400
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	3.56e-04	0.2130	0.034400
REACTOME EICOSANOIDS	12	4.27e-04	0.5870	0.038900
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	4.57e-04	0.1260	0.039500
REACTOME INNATE IMMUNE SYSTEM	1002	5.61e-04	0.0644	0.046100
REACTOME GLUCURONIDATION	23	6.68e-04	0.4100	0.051200
REACTOME GPCR LIGAND BINDING	444	6.86e-04	-0.0940	0.051200
REACTOME INTERLEUKIN 18 SIGNALING	8	7.57e-04	-0.6880	0.054000
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	8.15e-04	0.4220	0.054500
REACTOME HIV INFECTION	223	8.29e-04	0.1300	0.054500
REACTOME RRNA PROCESSING	192	9.49e-04	0.1380	0.059900
REACTOME HIV LIFE CYCLE	145	1.10e-03	0.1570	0.065600
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	1.15e-03	-0.1070	0.065600
REACTOME INFECTIOUS DISEASE	910	1.16e-03	0.0635	0.065600
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.22e-03	0.1480	0.066600
REACTOME PROTEIN LOCALIZATION	153	1.91e-03	0.1450	0.098200
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	1.91e-03	0.7320	0.098200
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	2.27e-03	0.2420	0.113000
REACTOME AMINE LIGAND BINDING RECEPTORS	40	3.26e-03	-0.2690	0.155000
REACTOME SELENOAMINO ACID METABOLISM	108	3.30e-03	0.1640	0.155000
REACTOME DRUG ADME	103	3.43e-03	0.1670	0.156000
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	3.54e-03	0.3970	0.157000
REACTOME POTASSIUM CHANNELS	102	4.19e-03	-0.1640	0.175000
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	4.24e-03	0.2880	0.175000
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	4.36e-03	-0.1040	0.175000
REACTOME SIGNALING BY ROBO RECEPTORS	206	4.38e-03	0.1150	0.175000
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	4.62e-03	-0.1200	0.181000
REACTOME DNA METHYLATION	58	4.94e-03	-0.2130	0.189000
REACTOME BIOLOGICAL OXIDATIONS	210	5.62e-03	0.1110	0.210000
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	6.10e-03	0.2080	0.218000
REACTOME LGI ADAM INTERACTIONS	14	6.11e-03	-0.4230	0.218000
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	6.30e-03	-0.7050	0.220000
REACTOME MRNA SPLICING	197	6.93e-03	0.1120	0.237000
REACTOME FERTILIZATION	26	7.15e-03	0.3050	0.238000
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	7.25e-03	-0.4900	0.238000

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME METABOLISM OF RNA	675	5.37e-07	1.13e-01	0.000882
REACTOME TRANSLATION	278	2.07e-06	1.65e-01	0.001700
REACTOME INFLUENZA INFECTION	149	6.00e-06	2.15e-01	0.003280
REACTOME NEUTROPHIL DEGRANULATION	460	9.03e-06	1.21e-01	0.003710
REACTOME NONSENSE MEDIATED DECAY NMD	107	1.40e-05	2.43e-01	0.004200
REACTOME ASPIRIN ADME	42	1.54e-05	3.85e-01	0.004200
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	1.90e-05	2.36e-01	0.004470
REACTOME SNRNP ASSEMBLY	53	5.11e-05	3.22e-01	0.009640
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	5.28e-05	2.51e-01	0.009640
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	7.42e-05	2.24e-01	0.012000
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	8.73e-05	3.34e-01	0.012000
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	8.75e-05	-4.94e-01	0.012000
REACTOME FATTY ACIDS	15	9.97e-05	5.80e-01	0.012600
REACTOME CELLULAR RESPONSE TO STARVATION	147	1.35e-04	1.82e-01	0.015800
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	2.14e-04	-3.34e-01	0.023400
REACTOME NEURONAL SYSTEM	388	3.47e-04	-1.06e-01	0.034400
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	3.56e-04	2.13e-01	0.034400
REACTOME EICOSANOIDS	12	4.27e-04	5.87e-01	0.038900
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	4.57e-04	1.26e-01	0.039500
REACTOME INNATE IMMUNE SYSTEM	1002	5.61e-04	6.44e-02	0.046100
REACTOME GLUCURONIDATION	23	6.68e-04	4.10e-01	0.051200
REACTOME GPCR LIGAND BINDING	444	6.86e-04	-9.40e-02	0.051200
REACTOME INTERLEUKIN 18 SIGNALING	8	7.57e-04	-6.88e-01	0.054000
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	8.15e-04	4.22e-01	0.054500
REACTOME HIV INFECTION	223	8.29e-04	1.30e-01	0.054500
REACTOME RRNA PROCESSING	192	9.49e-04	1.38e-01	0.059900
REACTOME HIV LIFE CYCLE	145	1.10e-03	1.57e-01	0.065600
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	1.15e-03	-1.07e-01	0.065600
REACTOME INFECTIOUS DISEASE	910	1.16e-03	6.35e-02	0.065600
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.22e-03	1.48e-01	0.066600
REACTOME PROTEIN LOCALIZATION	153	1.91e-03	1.45e-01	0.098200
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	1.91e-03	7.32e-01	0.098200
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	2.27e-03	2.42e-01	0.113000
REACTOME AMINE LIGAND BINDING RECEPTORS	40	3.26e-03	-2.69e-01	0.155000
REACTOME SELENOAMINO ACID METABOLISM	108	3.30e-03	1.64e-01	0.155000
REACTOME DRUG ADME	103	3.43e-03	1.67e-01	0.156000
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	3.54e-03	3.97e-01	0.157000
REACTOME POTASSIUM CHANNELS	102	4.19e-03	-1.64e-01	0.175000
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	4.24e-03	2.88e-01	0.175000
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	4.36e-03	-1.04e-01	0.175000
REACTOME SIGNALING BY ROBO RECEPTORS	206	4.38e-03	1.15e-01	0.175000
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	4.62e-03	-1.20e-01	0.181000
REACTOME DNA METHYLATION	58	4.94e-03	-2.13e-01	0.189000
REACTOME BIOLOGICAL OXIDATIONS	210	5.62e-03	1.11e-01	0.210000
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	6.10e-03	2.08e-01	0.218000
REACTOME LGI ADAM INTERACTIONS	14	6.11e-03	-4.23e-01	0.218000
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	6.30e-03	-7.05e-01	0.220000
REACTOME MRNA SPLICING	197	6.93e-03	1.12e-01	0.237000
REACTOME FERTILIZATION	26	7.15e-03	3.05e-01	0.238000
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	7.25e-03	-4.90e-01	0.238000
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	7.86e-03	-2.76e-01	0.253000
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	8.08e-03	-1.11e-01	0.255000
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	1.05e-02	1.32e-01	0.324000
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	1.09e-02	2.52e-01	0.330000
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	1.18e-02	-1.53e-01	0.348000
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	1.19e-02	-1.80e-01	0.348000
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	1.22e-02	-5.12e-01	0.352000
REACTOME AMINO ACID CONJUGATION	9	1.28e-02	4.79e-01	0.363000
REACTOME STRIATED MUSCLE CONTRACTION	35	1.34e-02	-2.41e-01	0.374000
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	1.53e-02	-3.21e-01	0.404000
REACTOME VASOPRESSIN LIKE RECEPTORS	5	1.54e-02	-6.26e-01	0.404000
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	1.55e-02	-5.71e-01	0.404000
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	1.56e-02	-1.37e-01	0.404000
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	1.58e-02	5.69e-01	0.404000
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	1.64e-02	-1.81e-01	0.404000
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	1.64e-02	2.28e-01	0.404000
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	1.65e-02	2.34e-01	0.404000
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	1.70e-02	1.57e-01	0.411000
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	1.83e-02	1.55e-01	0.435000
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	1.92e-02	1.34e-01	0.451000
REACTOME LYSINE CATABOLISM	12	1.95e-02	-3.89e-01	0.452000
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	2.00e-02	-2.21e-01	0.454000
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	2.02e-02	-6.00e-01	0.454000
REACTOME BILE ACID AND BILE SALT METABOLISM	45	2.16e-02	1.98e-01	0.478000
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	2.20e-02	3.82e-01	0.479000
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	2.21e-02	-5.39e-01	0.479000
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	2.32e-02	-3.01e-01	0.495000
REACTOME GAP JUNCTION ASSEMBLY	36	2.44e-02	-2.17e-01	0.511000
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	2.46e-02	-1.37e-01	0.511000
REACTOME ELASTIC FIBRE FORMATION	44	2.52e-02	-1.95e-01	0.516000
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	2.57e-02	-1.64e-01	0.520000
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	2.63e-02	3.43e-01	0.520000
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	2.64e-02	2.23e-01	0.520000
REACTOME INTERLEUKIN 23 SIGNALING	9	2.67e-02	4.26e-01	0.520000
REACTOME NCAM1 INTERACTIONS	41	2.71e-02	-1.99e-01	0.520000
REACTOME SARS COV 2 HOST INTERACTIONS	191	2.72e-02	9.26e-02	0.520000
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	2.83e-02	5.17e-01	0.533000
REACTOME MISCELLANEOUS SUBSTRATES	12	2.96e-02	3.63e-01	0.548000
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	3.03e-02	1.60e-01	0.548000
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	3.08e-02	4.71e-01	0.548000
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	3.09e-02	3.60e-01	0.548000
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	3.10e-02	-3.76e-01	0.548000
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	3.10e-02	2.14e-01	0.548000
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	3.17e-02	-1.72e-01	0.551000
REACTOME SARS COV INFECTIONS	392	3.19e-02	6.31e-02	0.551000
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	3.39e-02	-1.41e-01	0.574000
REACTOME MRNA SPLICING MINOR PATHWAY	49	3.39e-02	1.75e-01	0.574000
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	3.51e-02	2.22e-01	0.582000
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	3.51e-02	-1.59e-01	0.582000
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	3.57e-02	1.22e-01	0.586000
REACTOME STAT5 ACTIVATION	7	3.79e-02	4.53e-01	0.615000
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	3.82e-02	1.66e-01	0.615000
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	3.86e-02	1.57e-01	0.615000
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	3.90e-02	-1.47e-01	0.616000
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	4.00e-02	2.13e-01	0.622000
REACTOME SIGNALING BY SCF KIT	42	4.08e-02	1.82e-01	0.622000
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	4.09e-02	1.54e-01	0.622000
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	4.16e-02	-3.92e-01	0.622000
REACTOME 2 LTR CIRCLE FORMATION	7	4.18e-02	4.44e-01	0.622000
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	4.20e-02	1.27e-01	0.622000
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	4.20e-02	-1.52e-01	0.622000
REACTOME INTEGRATION OF PROVIRUS	9	4.29e-02	3.90e-01	0.629000
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	4.35e-02	4.12e-01	0.632000
REACTOME HEME DEGRADATION	15	4.51e-02	2.99e-01	0.646000
REACTOME DOPAMINE RECEPTORS	5	4.57e-02	-5.16e-01	0.646000
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	4.60e-02	1.40e-01	0.646000
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	4.70e-02	2.21e-01	0.646000
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	4.74e-02	4.67e-01	0.646000
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	4.76e-02	1.31e-01	0.646000
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	4.77e-02	1.88e-01	0.646000
REACTOME ARACHIDONIC ACID METABOLISM	57	4.78e-02	1.52e-01	0.646000
REACTOME SUPPRESSION OF APOPTOSIS	7	4.80e-02	4.32e-01	0.646000
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	4.94e-02	-3.59e-01	0.655000
REACTOME GABA RECEPTOR ACTIVATION	57	4.94e-02	-1.50e-01	0.655000
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	5.08e-02	1.96e-01	0.665000
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	5.13e-02	1.55e-01	0.665000
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	5.17e-02	2.40e-01	0.665000
REACTOME DECTIN 2 FAMILY	26	5.20e-02	-2.20e-01	0.665000
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	5.24e-02	-1.73e-01	0.665000
REACTOME SPERM MOTILITY AND TAXES	9	5.27e-02	3.73e-01	0.665000
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	5.38e-02	1.15e-01	0.668000
REACTOME PARACETAMOL ADME	26	5.40e-02	2.18e-01	0.668000
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	5.41e-02	-3.21e-01	0.668000
REACTOME TCR SIGNALING	113	5.49e-02	1.05e-01	0.671000
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	5.51e-02	-2.77e-01	0.671000
REACTOME G ALPHA S SIGNALLING EVENTS	155	5.60e-02	-8.89e-02	0.676000
REACTOME RHO GTPASES ACTIVATE PKNS	86	5.72e-02	-1.19e-01	0.682000
REACTOME COLLAGEN DEGRADATION	61	5.84e-02	-1.40e-01	0.682000
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	5.90e-02	-1.13e-01	0.682000
REACTOME SIGNALING BY GPCR	673	5.97e-02	-4.26e-02	0.682000
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	5.98e-02	1.64e-01	0.682000
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	6.00e-02	1.34e-01	0.682000
REACTOME MET RECEPTOR ACTIVATION	6	6.13e-02	4.41e-01	0.682000
REACTOME PTEN REGULATION	135	6.16e-02	9.32e-02	0.682000
REACTOME DAP12 INTERACTIONS	37	6.17e-02	1.78e-01	0.682000
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	6.18e-02	3.25e-01	0.682000
REACTOME MITOCHONDRIAL TRANSLATION	93	6.19e-02	1.12e-01	0.682000
REACTOME G ALPHA Z SIGNALLING EVENTS	48	6.22e-02	-1.56e-01	0.682000
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	6.27e-02	1.79e-01	0.682000
REACTOME OLFACTORY SIGNALING PATHWAY	348	6.27e-02	5.81e-02	0.682000
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	6.32e-02	1.68e-01	0.682000
REACTOME FLT3 SIGNALING	38	6.33e-02	1.74e-01	0.682000
REACTOME INTERLEUKIN 12 SIGNALING	43	6.35e-02	1.64e-01	0.682000
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	6.49e-02	-1.36e-01	0.692000
REACTOME FGFR2 ALTERNATIVE SPLICING	27	6.59e-02	2.04e-01	0.695000
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	6.63e-02	1.58e-01	0.695000
REACTOME SYNTHESIS OF KETONE BODIES	8	6.70e-02	-3.74e-01	0.695000
REACTOME ACTIVATION OF SMO	18	6.76e-02	-2.49e-01	0.695000
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	6.77e-02	-2.25e-01	0.695000
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	6.77e-02	-1.33e-01	0.695000
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	6.85e-02	-6.88e-02	0.699000
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	6.91e-02	1.86e-01	0.699000
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	6.94e-02	1.53e-01	0.699000
REACTOME PURINE CATABOLISM	17	7.01e-02	-2.54e-01	0.702000
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	7.12e-02	1.36e-01	0.705000
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	7.25e-02	8.64e-02	0.705000
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	7.28e-02	-1.48e-01	0.705000
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	7.36e-02	1.58e-01	0.705000
REACTOME REGULATION OF SIGNALING BY NODAL	9	7.42e-02	3.44e-01	0.705000
REACTOME METABOLISM OF LIPIDS	709	7.42e-02	3.94e-02	0.705000
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	7.47e-02	-3.89e-01	0.705000
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	7.55e-02	-8.89e-02	0.705000
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	7.61e-02	1.94e-01	0.705000
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	7.63e-02	-1.60e-01	0.705000
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	7.64e-02	-1.24e-01	0.705000
REACTOME METHYLATION	14	7.64e-02	2.74e-01	0.705000
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	7.71e-02	1.42e-01	0.705000
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	7.71e-02	-2.95e-01	0.705000
REACTOME PEROXISOMAL PROTEIN IMPORT	62	7.74e-02	1.30e-01	0.705000
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	7.75e-02	-9.61e-02	0.705000
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	7.77e-02	-1.26e-01	0.705000
REACTOME SCAVENGING OF HEME FROM PLASMA	13	8.14e-02	2.79e-01	0.731000
REACTOME GASTRULATION	49	8.15e-02	-1.44e-01	0.731000
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	8.26e-02	1.83e-01	0.738000
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	8.33e-02	-3.78e-01	0.739000
REACTOME NUCLEOTIDE CATABOLISM	35	8.64e-02	-1.67e-01	0.743000
REACTOME SARS COV 2 INFECTION	281	8.66e-02	5.94e-02	0.743000
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	8.70e-02	2.47e-01	0.743000
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	8.75e-02	3.12e-01	0.743000
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	8.78e-02	-1.37e-01	0.743000
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	8.81e-02	-3.72e-01	0.743000
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	8.82e-02	1.52e-01	0.743000
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	8.84e-02	4.02e-01	0.743000
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	8.90e-02	-1.82e-01	0.743000
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	8.90e-02	-1.45e-01	0.743000
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	8.91e-02	2.62e-01	0.743000
REACTOME REGULATION OF KIT SIGNALING	16	8.91e-02	2.45e-01	0.743000
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	9.14e-02	2.94e-01	0.752000
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	9.24e-02	-9.69e-02	0.752000
REACTOME ANTIMICROBIAL PEPTIDES	76	9.29e-02	1.11e-01	0.752000
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	9.29e-02	-8.95e-02	0.752000
REACTOME FATTY ACID METABOLISM	170	9.30e-02	7.47e-02	0.752000
REACTOME HDACS DEACETYLATE HISTONES	85	9.46e-02	-1.05e-01	0.752000
REACTOME ABC TRANSPORTER DISORDERS	76	9.51e-02	1.11e-01	0.752000
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	9.53e-02	2.10e-01	0.752000
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	9.53e-02	2.27e-01	0.752000
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	9.56e-02	1.93e-01	0.752000
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	9.57e-02	1.96e-01	0.752000
REACTOME ACYL CHAIN REMODELLING OF PE	29	9.58e-02	-1.79e-01	0.752000
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	9.64e-02	1.32e-01	0.753000
REACTOME NEGATIVE REGULATION OF FLT3	15	9.70e-02	2.47e-01	0.754000
REACTOME UNWINDING OF DNA	12	9.74e-02	2.76e-01	0.754000
REACTOME CELLULAR SENESCENCE	189	9.85e-02	-6.97e-02	0.758000
REACTOME COENZYME A BIOSYNTHESIS	8	9.96e-02	3.36e-01	0.758000
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	9.96e-02	1.01e-01	0.758000
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	1.00e-01	1.40e-01	0.758000
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	1.00e-01	-1.02e-01	0.758000
REACTOME SENSORY PERCEPTION	555	1.02e-01	4.06e-02	0.767000
REACTOME RAP1 SIGNALLING	16	1.05e-01	2.34e-01	0.785000
REACTOME PYRIMIDINE CATABOLISM	12	1.06e-01	-2.70e-01	0.785000
REACTOME INFLAMMASOMES	21	1.06e-01	2.04e-01	0.785000
REACTOME ADRENOCEPTORS	9	1.06e-01	-3.11e-01	0.786000
REACTOME SIGNALING BY KIT IN DISEASE	20	1.07e-01	2.08e-01	0.788000
REACTOME APOPTOSIS	173	1.10e-01	7.05e-02	0.803000
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	1.10e-01	-1.84e-01	0.803000
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	1.11e-01	3.76e-01	0.803000
REACTOME AMINO ACIDS REGULATE MTORC1	53	1.11e-01	1.26e-01	0.804000
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	1.12e-01	-1.20e-01	0.804000
REACTOME SARS COV 1 HOST INTERACTIONS	92	1.13e-01	9.57e-02	0.804000
REACTOME DISEASES OF METABOLISM	237	1.13e-01	-5.98e-02	0.804000
REACTOME MET RECEPTOR RECYCLING	10	1.13e-01	2.89e-01	0.804000
REACTOME BASE EXCISION REPAIR	87	1.15e-01	-9.79e-02	0.808000
REACTOME NTRK2 ACTIVATES RAC1	5	1.15e-01	-4.07e-01	0.808000
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.16e-01	3.92e-02	0.808000
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	1.16e-01	-9.28e-02	0.808000
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	1.16e-01	1.17e-01	0.808000
REACTOME RAB GERANYLGERANYLATION	57	1.18e-01	1.20e-01	0.808000
REACTOME CELL CYCLE CHECKPOINTS	284	1.18e-01	5.38e-02	0.808000
REACTOME MITOPHAGY	28	1.19e-01	1.70e-01	0.808000
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	1.19e-01	-2.41e-01	0.808000
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	1.19e-01	1.52e-01	0.808000
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	1.19e-01	1.52e-01	0.808000
REACTOME SULFIDE OXIDATION TO SULFATE	6	1.20e-01	-3.66e-01	0.810000
REACTOME GABA B RECEPTOR ACTIVATION	43	1.20e-01	-1.37e-01	0.810000
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	1.22e-01	1.49e-01	0.811000
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	1.22e-01	3.38e-01	0.811000
REACTOME HYDROLYSIS OF LPC	9	1.22e-01	-2.98e-01	0.811000
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	1.24e-01	-3.63e-01	0.816000
REACTOME MUSCLE CONTRACTION	197	1.24e-01	-6.36e-02	0.816000
REACTOME VLDL CLEARANCE	6	1.25e-01	-3.62e-01	0.818000
REACTOME FIBRONECTIN MATRIX FORMATION	6	1.26e-01	3.61e-01	0.820000
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	1.26e-01	2.03e-01	0.820000
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	1.26e-01	3.95e-01	0.820000
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	1.27e-01	2.94e-01	0.820000
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	1.29e-01	-2.19e-01	0.830000
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	1.30e-01	3.09e-01	0.832000
REACTOME MITOCHONDRIAL BIOGENESIS	87	1.30e-01	9.38e-02	0.832000
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	1.31e-01	-3.09e-01	0.832000
REACTOME MRNA EDITING C TO U CONVERSION	8	1.32e-01	-3.08e-01	0.836000
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.32e-01	-7.79e-02	0.836000
REACTOME PROGRAMMED CELL DEATH	204	1.33e-01	6.10e-02	0.836000
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	1.34e-01	7.65e-02	0.837000
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	1.34e-01	-9.51e-02	0.838000
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	1.36e-01	3.85e-01	0.840000
REACTOME SIGNALING BY MAPK MUTANTS	6	1.39e-01	-3.49e-01	0.840000
REACTOME PI METABOLISM	79	1.39e-01	9.62e-02	0.840000
REACTOME SPHINGOLIPID METABOLISM	84	1.39e-01	9.33e-02	0.840000
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	1.40e-01	8.51e-02	0.840000
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	1.40e-01	1.91e-01	0.840000
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	1.40e-01	2.36e-01	0.840000
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	1.40e-01	1.56e-01	0.840000
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	1.40e-01	-3.22e-01	0.840000
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	1.41e-01	3.22e-01	0.840000
REACTOME DAP12 SIGNALING	27	1.41e-01	1.64e-01	0.840000
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	1.42e-01	1.60e-01	0.840000
REACTOME PYRIMIDINE SALVAGE	10	1.43e-01	2.68e-01	0.840000
REACTOME KETONE BODY METABOLISM	9	1.43e-01	-2.82e-01	0.840000
REACTOME G2 M CHECKPOINTS	162	1.45e-01	6.64e-02	0.840000
REACTOME ENOS ACTIVATION	11	1.45e-01	-2.54e-01	0.840000
REACTOME SIGNALING BY HIPPO	19	1.45e-01	-1.93e-01	0.840000
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	1.46e-01	-2.24e-01	0.840000
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	1.47e-01	1.38e-01	0.840000
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	1.47e-01	1.28e-01	0.840000
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	1.49e-01	-1.87e-01	0.840000
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	1.49e-01	2.78e-01	0.840000
REACTOME PLASMA LIPOPROTEIN REMODELING	33	1.49e-01	1.45e-01	0.840000
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	1.49e-01	2.15e-01	0.840000
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	1.50e-01	3.72e-01	0.840000
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	1.50e-01	-1.20e-01	0.840000
REACTOME INTERLEUKIN 21 SIGNALING	9	1.51e-01	2.76e-01	0.840000
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	1.51e-01	1.05e-01	0.840000
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	1.52e-01	1.95e-01	0.840000
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	1.53e-01	-3.12e-01	0.840000
REACTOME PENTOSE PHOSPHATE PATHWAY	12	1.53e-01	2.38e-01	0.840000
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	1.53e-01	2.61e-01	0.840000
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	1.53e-01	2.29e-01	0.840000
REACTOME SIGNALING BY EGFR IN CANCER	25	1.53e-01	1.65e-01	0.840000
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	1.53e-01	1.89e-01	0.840000
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	1.54e-01	-1.27e-01	0.840000
REACTOME MEIOTIC RECOMBINATION	80	1.55e-01	-9.19e-02	0.840000
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	1.55e-01	1.09e-01	0.840000
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	1.56e-01	-1.50e-01	0.840000
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	1.56e-01	-2.47e-01	0.840000
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	1.56e-01	-2.05e-01	0.840000
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	1.57e-01	1.55e-01	0.840000
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	1.57e-01	5.44e-02	0.840000
REACTOME P2Y RECEPTORS	9	1.57e-01	2.72e-01	0.840000
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	1.57e-01	1.22e-01	0.840000
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	1.58e-01	-1.92e-01	0.840000
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	1.59e-01	1.82e-01	0.843000
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	1.60e-01	-3.31e-01	0.847000
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	1.63e-01	1.33e-01	0.856000
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	1.63e-01	3.60e-01	0.857000
REACTOME SIGNALING BY MET	78	1.66e-01	9.07e-02	0.865000
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	1.66e-01	-1.75e-01	0.865000
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	1.68e-01	1.83e-01	0.865000
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	1.70e-01	3.55e-01	0.865000
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	1.70e-01	9.49e-02	0.865000
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	1.70e-01	1.16e-01	0.865000
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	1.70e-01	1.82e-01	0.865000
REACTOME FASL CD95L SIGNALING	5	1.71e-01	-3.54e-01	0.865000
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	1.71e-01	1.40e-01	0.865000
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	1.72e-01	8.84e-02	0.865000
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	1.72e-01	2.19e-01	0.865000
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	1.72e-01	2.03e-01	0.865000
REACTOME CELLULAR HEXOSE TRANSPORT	21	1.73e-01	-1.72e-01	0.865000
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	1.73e-01	4.58e-02	0.865000
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	1.74e-01	1.20e-01	0.865000
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	1.74e-01	-1.21e-01	0.865000
REACTOME SEROTONIN RECEPTORS	11	1.74e-01	-2.37e-01	0.865000
REACTOME FLT3 SIGNALING IN DISEASE	28	1.74e-01	1.48e-01	0.865000
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	1.77e-01	1.27e-01	0.874000
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	1.77e-01	-2.08e-01	0.874000
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	1.79e-01	1.35e-01	0.879000
REACTOME HCMV EARLY EVENTS	128	1.79e-01	-6.87e-02	0.879000
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	1.81e-01	3.15e-01	0.883000
REACTOME MRNA EDITING	10	1.81e-01	-2.44e-01	0.883000
REACTOME RAC2 GTPASE CYCLE	81	1.82e-01	8.58e-02	0.883000
REACTOME VITAMINS	6	1.82e-01	-3.14e-01	0.884000
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	1.83e-01	9.62e-02	0.885000
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	1.84e-01	1.86e-01	0.885000
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	1.85e-01	1.04e-01	0.885000
REACTOME MITOCHONDRIAL UNCOUPLING	5	1.85e-01	-3.42e-01	0.885000
REACTOME ECM PROTEOGLYCANS	73	1.86e-01	-8.95e-02	0.885000
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	1.87e-01	-7.04e-02	0.885000
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	1.87e-01	-1.66e-01	0.885000
REACTOME FCGR ACTIVATION	11	1.89e-01	-2.29e-01	0.885000
REACTOME STABILIZATION OF P53	56	1.89e-01	1.02e-01	0.885000
REACTOME HIV TRANSCRIPTION INITIATION	43	1.89e-01	1.16e-01	0.885000
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	1.89e-01	-3.09e-01	0.885000
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	1.89e-01	-2.12e-02	0.885000
REACTOME RHOG GTPASE CYCLE	71	1.90e-01	9.00e-02	0.885000
REACTOME O LINKED GLYCOSYLATION	109	1.91e-01	-7.25e-02	0.888000
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	1.93e-01	-1.37e-01	0.895000
REACTOME SIGNALING BY CSF3 G CSF	30	1.94e-01	1.37e-01	0.896000
REACTOME CHYLOMICRON ASSEMBLY	10	1.96e-01	2.36e-01	0.899000
REACTOME DSCAM INTERACTIONS	11	1.96e-01	-2.25e-01	0.899000
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	1.97e-01	-1.49e-01	0.899000
REACTOME GLYCOGEN SYNTHESIS	13	1.98e-01	-2.06e-01	0.899000
REACTOME SYNTHESIS OF DNA	119	1.98e-01	6.83e-02	0.899000
REACTOME SIGNALING BY PDGFR IN DISEASE	20	1.99e-01	1.66e-01	0.899000
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	1.99e-01	1.26e-01	0.899000
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	1.99e-01	3.32e-01	0.899000
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	2.01e-01	-1.37e-01	0.904000
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	2.03e-01	-8.09e-02	0.904000
REACTOME CRMPS IN SEMA3A SIGNALING	15	2.03e-01	1.90e-01	0.904000
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	2.03e-01	1.01e-01	0.904000
REACTOME BICARBONATE TRANSPORTERS	10	2.03e-01	-2.32e-01	0.904000
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	2.03e-01	9.06e-02	0.904000
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	2.05e-01	-2.99e-01	0.904000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	2.05e-01	3.27e-01	0.904000
REACTOME CELL CYCLE	666	2.06e-01	2.88e-02	0.904000
REACTOME PHYSIOLOGICAL FACTORS	14	2.06e-01	-1.95e-01	0.904000
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	2.06e-01	1.17e-01	0.904000
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	2.07e-01	-2.76e-01	0.904000
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	2.07e-01	7.34e-02	0.904000
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	2.08e-01	-2.02e-01	0.906000
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	2.08e-01	-2.42e-01	0.906000
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	2.09e-01	-1.18e-01	0.906000
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	2.12e-01	-2.40e-01	0.914000
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	2.12e-01	1.65e-01	0.914000
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	2.13e-01	-2.72e-01	0.914000
REACTOME RHOBTB1 GTPASE CYCLE	22	2.14e-01	-1.53e-01	0.914000
REACTOME SYNTHESIS OF PA	38	2.15e-01	-1.16e-01	0.914000
REACTOME SODIUM CALCIUM EXCHANGERS	11	2.15e-01	-2.16e-01	0.914000
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	2.17e-01	1.13e-01	0.914000
REACTOME TRIGLYCERIDE CATABOLISM	23	2.17e-01	1.49e-01	0.914000
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	2.19e-01	-1.67e-01	0.914000
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	2.19e-01	9.94e-02	0.914000
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	2.20e-01	-1.59e-01	0.914000
REACTOME LDL REMODELING	6	2.20e-01	2.89e-01	0.914000
REACTOME METALLOPROTEASE DUBS	36	2.20e-01	-1.18e-01	0.914000
REACTOME APOPTOTIC EXECUTION PHASE	49	2.20e-01	1.01e-01	0.914000
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	2.21e-01	-2.36e-01	0.914000
REACTOME HCMV INFECTION	152	2.21e-01	-5.75e-02	0.914000
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	2.22e-01	-7.66e-02	0.914000
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	2.24e-01	-2.12e-01	0.914000
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	2.24e-01	1.88e-01	0.914000
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	2.25e-01	2.11e-01	0.914000
REACTOME PECAM1 INTERACTIONS	12	2.25e-01	2.02e-01	0.914000
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	2.25e-01	1.75e-01	0.914000
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	2.25e-01	-7.02e-02	0.914000
REACTOME MAPK3 ERK1 ACTIVATION	10	2.25e-01	2.21e-01	0.914000
REACTOME SARS COV 1 INFECTION	136	2.26e-01	6.02e-02	0.914000
REACTOME HDL REMODELING	10	2.26e-01	2.21e-01	0.914000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	2.26e-01	-6.37e-02	0.914000
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	2.27e-01	1.04e-01	0.914000
REACTOME SIGNALING BY ALK IN CANCER	53	2.28e-01	9.58e-02	0.914000
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	2.28e-01	1.69e-01	0.914000
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	2.29e-01	-1.31e-01	0.916000
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	2.29e-01	-1.45e-01	0.916000
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	2.32e-01	2.44e-01	0.921000
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	2.33e-01	-2.29e-01	0.921000
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	2.34e-01	-1.99e-01	0.921000
REACTOME ACYL CHAIN REMODELING OF CL	5	2.34e-01	3.07e-01	0.921000
REACTOME DEVELOPMENTAL BIOLOGY	1115	2.35e-01	-2.11e-02	0.921000
REACTOME SIGNALING BY FGFR2 IIIA TM	19	2.35e-01	1.57e-01	0.921000
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	2.35e-01	2.07e-01	0.921000
REACTOME COMPLEX I BIOGENESIS	49	2.38e-01	9.75e-02	0.921000
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	2.39e-01	-1.36e-01	0.921000
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	2.40e-01	-1.52e-01	0.921000
REACTOME SIGNALING BY FGFR IN DISEASE	62	2.41e-01	8.62e-02	0.921000
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	2.41e-01	8.53e-02	0.921000
REACTOME PEROXISOMAL LIPID METABOLISM	28	2.42e-01	1.28e-01	0.921000
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	2.43e-01	-1.80e-01	0.921000
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	2.44e-01	3.01e-01	0.921000
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	2.44e-01	2.75e-01	0.921000
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	2.45e-01	1.47e-01	0.921000
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	2.45e-01	9.90e-02	0.921000
REACTOME PROTEIN METHYLATION	17	2.46e-01	-1.63e-01	0.921000
REACTOME RHO GTPASE CYCLE	423	2.46e-01	3.29e-02	0.921000
REACTOME COLLAGEN FORMATION	88	2.47e-01	-7.14e-02	0.921000
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	2.47e-01	-2.53e-01	0.921000
REACTOME DNA STRAND ELONGATION	31	2.47e-01	1.20e-01	0.921000
REACTOME SURFACTANT METABOLISM	28	2.48e-01	1.26e-01	0.921000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	2.49e-01	-2.22e-01	0.921000
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	2.49e-01	-2.22e-01	0.921000
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	2.50e-01	2.97e-01	0.921000
REACTOME NADE MODULATES DEATH SIGNALLING	5	2.50e-01	-2.97e-01	0.921000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	2.50e-01	-2.35e-01	0.921000
REACTOME MET ACTIVATES PTPN11	5	2.51e-01	2.97e-01	0.921000
REACTOME SEMAPHORIN INTERACTIONS	61	2.51e-01	8.50e-02	0.921000
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	2.51e-01	-4.87e-02	0.921000
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	2.51e-01	-2.34e-01	0.921000
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	2.51e-01	8.11e-02	0.921000
REACTOME PROTEIN REPAIR	6	2.52e-01	-2.70e-01	0.921000
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	2.52e-01	4.85e-02	0.921000
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	2.52e-01	3.56e-02	0.921000
REACTOME AUTOPHAGY	144	2.52e-01	5.53e-02	0.921000
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	2.52e-01	2.50e-01	0.921000
REACTOME ABACAVIR ADME	9	2.53e-01	-2.20e-01	0.921000
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	2.54e-01	-1.90e-01	0.921000
REACTOME TRNA AMINOACYLATION	40	2.54e-01	1.04e-01	0.921000
REACTOME AMYLOID FIBER FORMATION	102	2.55e-01	-6.52e-02	0.924000
REACTOME SIGNALING BY NTRK2 TRKB	25	2.58e-01	1.31e-01	0.924000
REACTOME HISTIDINE CATABOLISM	8	2.58e-01	2.31e-01	0.924000
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	2.58e-01	1.02e-01	0.924000
REACTOME HS GAG BIOSYNTHESIS	28	2.58e-01	-1.23e-01	0.924000
REACTOME HIV TRANSCRIPTION ELONGATION	42	2.59e-01	1.01e-01	0.924000
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	2.59e-01	7.59e-02	0.924000
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	2.60e-01	2.66e-01	0.926000
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	2.61e-01	7.56e-02	0.927000
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	2.63e-01	1.16e-01	0.930000
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	2.63e-01	1.48e-01	0.930000
REACTOME RECYCLING OF EIF2 GDP	7	2.64e-01	2.44e-01	0.930000
REACTOME CA2 ACTIVATED K CHANNELS	9	2.64e-01	-2.15e-01	0.930000
REACTOME CIPROFLOXACIN ADME	5	2.64e-01	2.88e-01	0.930000
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	2.65e-01	1.02e-01	0.930000
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	2.67e-01	2.62e-01	0.935000
REACTOME CYP2E1 REACTIONS	10	2.69e-01	2.02e-01	0.935000
REACTOME S PHASE	159	2.70e-01	5.07e-02	0.935000
REACTOME SIGNALING BY NOTCH1	69	2.71e-01	-7.66e-02	0.935000
REACTOME DISEASES OF GLYCOSYLATION	137	2.71e-01	-5.44e-02	0.935000
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	2.72e-01	2.84e-01	0.935000
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	2.73e-01	1.29e-01	0.935000
REACTOME RESPONSE TO METAL IONS	14	2.74e-01	-1.69e-01	0.935000
REACTOME INWARDLY RECTIFYING K CHANNELS	35	2.75e-01	-1.07e-01	0.935000
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	2.75e-01	-8.92e-02	0.935000
REACTOME LIPID PARTICLE ORGANIZATION	6	2.76e-01	2.57e-01	0.935000
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	2.76e-01	1.48e-01	0.935000
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	2.76e-01	-1.62e-01	0.935000
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	2.77e-01	-5.80e-02	0.935000
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	2.79e-01	1.56e-01	0.935000
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	2.80e-01	-1.04e-01	0.935000
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	2.81e-01	2.08e-01	0.935000
REACTOME SIGNALING BY ERBB2 IN CANCER	26	2.81e-01	1.22e-01	0.935000
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	2.81e-01	8.48e-02	0.935000
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	2.83e-01	-2.34e-01	0.935000
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	2.85e-01	-5.59e-02	0.935000
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	2.85e-01	-1.86e-01	0.935000
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	2.85e-01	7.18e-02	0.935000
REACTOME MTORC1 MEDIATED SIGNALLING	23	2.86e-01	1.29e-01	0.935000
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	2.87e-01	6.85e-02	0.935000
REACTOME FORMATION OF AXIAL MESODERM	14	2.87e-01	-1.64e-01	0.935000
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	2.87e-01	2.32e-01	0.935000
REACTOME INTRA GOLGI TRAFFIC	43	2.87e-01	9.38e-02	0.935000
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	2.88e-01	-9.60e-02	0.935000
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	2.88e-01	-1.49e-01	0.935000
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	2.88e-01	1.31e-01	0.935000
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	2.88e-01	2.74e-01	0.935000
REACTOME CS DS DEGRADATION	12	2.88e-01	-1.77e-01	0.935000
REACTOME SEPARATION OF SISTER CHROMATIDS	184	2.88e-01	4.54e-02	0.935000
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	2.88e-01	1.70e-01	0.935000
REACTOME MEIOTIC SYNAPSIS	73	2.88e-01	-7.19e-02	0.935000
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	2.89e-01	1.58e-01	0.935000
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	2.89e-01	-7.54e-02	0.935000
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	2.91e-01	6.37e-02	0.935000
REACTOME FANCONI ANEMIA PATHWAY	35	2.91e-01	1.03e-01	0.935000
REACTOME PD 1 SIGNALING	21	2.91e-01	1.33e-01	0.935000
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	2.92e-01	-1.09e-01	0.935000
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	2.92e-01	1.52e-01	0.935000
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	2.92e-01	1.36e-01	0.935000
REACTOME HDL CLEARANCE	5	2.92e-01	2.72e-01	0.935000
REACTOME DEFECTIVE F9 ACTIVATION	5	2.94e-01	-2.71e-01	0.935000
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	2.94e-01	-9.36e-02	0.935000
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	2.94e-01	1.83e-01	0.935000
REACTOME SIGNALING BY NOTCH4	80	2.94e-01	6.78e-02	0.935000
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	2.95e-01	-3.56e-02	0.935000
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	2.96e-01	1.39e-01	0.935000
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	2.96e-01	-6.67e-02	0.936000
REACTOME GDP FUCOSE BIOSYNTHESIS	6	2.99e-01	2.45e-01	0.941000
REACTOME MET ACTIVATES RAS SIGNALING	11	3.00e-01	1.81e-01	0.941000
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	3.00e-01	-1.73e-01	0.941000
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	3.00e-01	6.54e-02	0.941000
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	3.01e-01	1.19e-01	0.942000
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	3.02e-01	1.19e-01	0.942000
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	3.02e-01	-1.72e-01	0.942000
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	3.04e-01	-1.08e-01	0.944000
REACTOME RHOBTB3 ATPASE CYCLE	8	3.05e-01	-2.09e-01	0.944000
REACTOME INOSITOL PHOSPHATE METABOLISM	45	3.05e-01	8.84e-02	0.944000
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	3.07e-01	1.32e-01	0.944000
REACTOME SIGNALING BY WNT	318	3.08e-01	-3.33e-02	0.944000
REACTOME CD22 MEDIATED BCR REGULATION	5	3.09e-01	2.63e-01	0.944000
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	3.10e-01	-2.22e-01	0.944000
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	3.11e-01	-1.00e-01	0.944000
REACTOME LIGAND RECEPTOR INTERACTIONS	8	3.11e-01	-2.07e-01	0.944000
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	3.11e-01	1.76e-01	0.944000
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	3.12e-01	7.61e-02	0.944000
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	3.13e-01	-6.93e-02	0.944000
REACTOME HCMV LATE EVENTS	110	3.13e-01	-5.57e-02	0.944000
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	3.13e-01	1.34e-01	0.944000
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	3.13e-01	1.08e-01	0.944000
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	3.13e-01	-2.60e-01	0.944000
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	3.14e-01	1.10e-01	0.944000
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	3.14e-01	2.37e-01	0.944000
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	3.14e-01	1.37e-01	0.944000
REACTOME SIGNALING BY MST1	5	3.15e-01	2.60e-01	0.944000
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	3.16e-01	1.45e-01	0.944000
REACTOME SIGNALING BY FGFR2	72	3.16e-01	6.83e-02	0.944000
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	3.16e-01	9.79e-02	0.944000
REACTOME MITOTIC SPINDLE CHECKPOINT	109	3.18e-01	5.54e-02	0.945000
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	3.18e-01	-1.32e-01	0.945000
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	3.19e-01	7.21e-02	0.945000
REACTOME DEGRADATION OF AXIN	54	3.19e-01	7.83e-02	0.945000
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	3.20e-01	-2.57e-01	0.945000
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	3.21e-01	1.81e-01	0.949000
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	3.24e-01	7.76e-02	0.952000
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	3.25e-01	-2.54e-01	0.952000
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	3.25e-01	1.09e-01	0.952000
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	3.25e-01	-1.80e-01	0.952000
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	3.26e-01	-5.96e-02	0.952000
REACTOME ACTIVATION OF C3 AND C5	6	3.26e-01	-2.31e-01	0.952000
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	3.27e-01	5.95e-02	0.952000
REACTOME MATURATION OF PROTEIN 3A	9	3.27e-01	1.89e-01	0.953000
REACTOME PREDNISONE ADME	10	3.28e-01	1.79e-01	0.954000
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	3.29e-01	1.29e-01	0.954000
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	3.29e-01	-1.41e-01	0.954000
REACTOME INSULIN PROCESSING	24	3.30e-01	-1.15e-01	0.954000
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	3.31e-01	-9.94e-02	0.954000
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	3.34e-01	1.02e-01	0.954000
REACTOME ION CHANNEL TRANSPORT	172	3.35e-01	4.26e-02	0.954000
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	3.35e-01	-1.86e-01	0.954000
REACTOME AURKA ACTIVATION BY TPX2	69	3.35e-01	-6.71e-02	0.954000
REACTOME CD209 DC SIGN SIGNALING	20	3.35e-01	1.24e-01	0.954000
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	3.36e-01	-1.54e-01	0.954000
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	3.36e-01	2.10e-01	0.954000
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	3.37e-01	5.12e-02	0.954000
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	3.37e-01	-2.10e-01	0.954000
REACTOME RUNX3 REGULATES WNT SIGNALING	8	3.37e-01	1.96e-01	0.954000
REACTOME DISEASES OF DNA REPAIR	51	3.38e-01	7.76e-02	0.954000
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	3.38e-01	8.99e-02	0.954000
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	3.39e-01	-2.25e-01	0.956000
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	3.40e-01	1.04e-01	0.956000
REACTOME TOLL LIKE RECEPTOR CASCADES	158	3.41e-01	-4.39e-02	0.956000
REACTOME INTESTINAL ABSORPTION	5	3.42e-01	-2.45e-01	0.956000
REACTOME TRANSPORT OF FATTY ACIDS	8	3.43e-01	-1.94e-01	0.956000
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	3.43e-01	6.03e-02	0.956000
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	3.43e-01	-1.41e-01	0.956000
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	3.43e-01	-2.24e-01	0.956000
REACTOME COMPLEMENT CASCADE	54	3.45e-01	7.43e-02	0.958000
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	3.46e-01	5.50e-02	0.958000
REACTOME CGMP EFFECTS	16	3.47e-01	1.36e-01	0.958000
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	3.48e-01	6.84e-02	0.958000
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	3.49e-01	1.71e-01	0.958000
REACTOME PROLACTIN RECEPTOR SIGNALING	15	3.49e-01	-1.40e-01	0.958000
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	3.49e-01	-2.04e-01	0.958000
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	3.50e-01	7.10e-02	0.958000
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	3.51e-01	-1.63e-01	0.958000
REACTOME LINOLEIC ACID LA METABOLISM	7	3.51e-01	-2.04e-01	0.958000
REACTOME MAPK6 MAPK4 SIGNALING	91	3.51e-01	5.66e-02	0.958000
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	3.51e-01	1.62e-01	0.958000
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	3.52e-01	7.77e-02	0.958000
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	3.52e-01	-1.07e-01	0.958000
REACTOME GPER1 SIGNALING	45	3.53e-01	-8.00e-02	0.958000
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	3.54e-01	1.89e-01	0.958000
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	3.54e-01	-2.39e-01	0.958000
REACTOME SUMOYLATION	179	3.54e-01	4.01e-02	0.958000
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	3.56e-01	-1.01e-01	0.958000
REACTOME ENDOGENOUS STEROLS	26	3.56e-01	-1.05e-01	0.958000
REACTOME CARDIAC CONDUCTION	125	3.56e-01	-4.78e-02	0.958000
REACTOME ACYL CHAIN REMODELLING OF PC	27	3.59e-01	-1.02e-01	0.960000
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	3.60e-01	-2.36e-01	0.960000
REACTOME SIGNALING BY NTRKS	132	3.60e-01	-4.61e-02	0.960000
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	3.61e-01	-1.08e-01	0.960000
REACTOME IRAK4 DEFICIENCY TLR2 4	17	3.61e-01	-1.28e-01	0.960000
REACTOME EPHRIN SIGNALING	17	3.62e-01	1.28e-01	0.960000
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	3.62e-01	-2.35e-01	0.960000
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	3.63e-01	-1.28e-01	0.960000
REACTOME METABOLISM OF PORPHYRINS	26	3.63e-01	1.03e-01	0.960000
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	3.63e-01	-4.58e-02	0.960000
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	3.64e-01	-9.28e-02	0.960000
REACTOME KILLING MECHANISMS	11	3.64e-01	-1.58e-01	0.960000
REACTOME MICRORNA MIRNA BIOGENESIS	25	3.64e-01	1.05e-01	0.960000
REACTOME POLYMERASE SWITCHING	13	3.66e-01	-1.45e-01	0.960000
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	3.66e-01	6.38e-02	0.960000
REACTOME INTERLEUKIN 15 SIGNALING	13	3.67e-01	1.44e-01	0.960000
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	3.68e-01	-1.34e-01	0.960000
REACTOME NEUROTRANSMITTER CLEARANCE	9	3.68e-01	-1.73e-01	0.960000
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	3.68e-01	-1.84e-01	0.960000
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	3.68e-01	-3.04e-02	0.960000
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	3.71e-01	1.38e-01	0.962000
REACTOME INACTIVATION OF CDC42 AND RAC1	8	3.71e-01	-1.83e-01	0.962000
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	3.71e-01	-1.13e-01	0.962000
REACTOME FREE FATTY ACID RECEPTORS	5	3.72e-01	2.30e-01	0.962000
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	3.73e-01	9.56e-02	0.962000
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	3.73e-01	-1.48e-01	0.962000
REACTOME RMTS METHYLATE HISTONE ARGININES	72	3.74e-01	-6.07e-02	0.962000
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	3.74e-01	1.71e-01	0.962000
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	3.75e-01	2.29e-01	0.963000
REACTOME ACTIVATION OF RAC1	12	3.75e-01	-1.48e-01	0.963000
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	3.78e-01	2.28e-01	0.963000
REACTOME DEADENYLATION OF MRNA	25	3.78e-01	1.02e-01	0.963000
REACTOME CELLULAR RESPONSES TO STIMULI	779	3.78e-01	1.86e-02	0.963000
REACTOME METABOLISM OF STEROIDS	150	3.80e-01	4.16e-02	0.963000
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	3.80e-01	-1.60e-01	0.963000
REACTOME N GLYCAN ANTENNAE ELONGATION	15	3.81e-01	1.31e-01	0.963000
REACTOME G ALPHA Q SIGNALLING EVENTS	206	3.82e-01	-3.54e-02	0.963000
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	3.82e-01	-5.88e-02	0.963000
REACTOME TRP CHANNELS	27	3.82e-01	9.72e-02	0.963000
REACTOME RAC1 GTPASE CYCLE	172	3.83e-01	3.86e-02	0.963000
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	3.83e-01	5.90e-02	0.963000
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	3.84e-01	-1.59e-01	0.963000
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	3.84e-01	8.05e-02	0.963000
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	3.85e-01	-2.25e-01	0.963000
REACTOME SIGNALING BY NTRK3 TRKC	17	3.85e-01	1.22e-01	0.963000
REACTOME CDC42 GTPASE CYCLE	144	3.85e-01	4.19e-02	0.963000
REACTOME RHOBTB GTPASE CYCLE	34	3.87e-01	-8.57e-02	0.963000
REACTOME INTERLEUKIN 6 SIGNALING	11	3.88e-01	1.50e-01	0.963000
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	3.89e-01	-1.06e-01	0.963000
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	3.89e-01	-9.23e-02	0.963000
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	3.90e-01	1.28e-01	0.963000
REACTOME CD28 CO STIMULATION	32	3.91e-01	8.77e-02	0.963000
REACTOME RECYCLING PATHWAY OF L1	43	3.91e-01	-7.56e-02	0.963000
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	3.92e-01	-1.32e-01	0.963000
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	3.93e-01	-8.73e-02	0.963000
REACTOME MTOR SIGNALLING	40	3.93e-01	7.81e-02	0.963000
REACTOME CTLA4 INHIBITORY SIGNALING	21	3.94e-01	1.07e-01	0.963000
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	3.94e-01	1.10e-01	0.963000
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	3.95e-01	2.64e-02	0.963000
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	3.95e-01	2.01e-01	0.963000
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	3.95e-01	-7.09e-02	0.963000
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	3.96e-01	1.63e-01	0.963000
REACTOME SHC MEDIATED CASCADE FGFR3	17	3.96e-01	1.19e-01	0.963000
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	3.96e-01	-2.19e-01	0.963000
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	3.97e-01	-1.48e-01	0.963000
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	3.97e-01	7.65e-02	0.963000
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	3.97e-01	-2.19e-01	0.963000
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	3.98e-01	4.56e-02	0.964000
REACTOME INTEGRATION OF ENERGY METABOLISM	105	3.99e-01	-4.77e-02	0.964000
REACTOME HATS ACETYLATE HISTONES	129	4.01e-01	-4.28e-02	0.964000
REACTOME DNA REPLICATION INITIATION	7	4.01e-01	1.83e-01	0.964000
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	4.01e-01	1.14e-01	0.964000
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	4.02e-01	-1.61e-01	0.964000
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	4.03e-01	-1.25e-01	0.964000
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	4.03e-01	1.71e-01	0.964000
REACTOME RSK ACTIVATION	5	4.03e-01	-2.16e-01	0.964000
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	4.04e-01	-7.93e-02	0.964000
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	4.04e-01	9.84e-02	0.964000
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	4.04e-01	8.26e-02	0.964000
REACTOME THE NLRP3 INFLAMMASOME	16	4.06e-01	1.20e-01	0.965000
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	4.07e-01	-1.38e-01	0.965000
REACTOME MEIOSIS	110	4.08e-01	-4.57e-02	0.965000
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	4.08e-01	-1.81e-01	0.965000
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	4.08e-01	-5.22e-02	0.965000
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	4.09e-01	-9.74e-02	0.965000
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	4.09e-01	-3.22e-02	0.965000
REACTOME INSULIN RECEPTOR RECYCLING	29	4.10e-01	8.84e-02	0.966000
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	4.12e-01	-8.38e-02	0.967000
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	4.12e-01	9.47e-02	0.967000
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	4.12e-01	1.09e-01	0.967000
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	4.14e-01	8.77e-02	0.968000
REACTOME ERK MAPK TARGETS	20	4.15e-01	-1.05e-01	0.968000
REACTOME SIGNALING BY INSULIN RECEPTOR	80	4.15e-01	5.27e-02	0.968000
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	4.15e-01	1.57e-01	0.968000
REACTOME PEPTIDE HORMONE METABOLISM	84	4.17e-01	-5.13e-02	0.970000
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	4.18e-01	1.91e-01	0.973000
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	4.20e-01	-1.04e-01	0.975000
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	4.21e-01	-1.07e-01	0.975000
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	4.22e-01	7.96e-02	0.975000
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	4.22e-01	-6.44e-02	0.975000
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	4.22e-01	-4.58e-02	0.975000
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	4.23e-01	-1.06e-01	0.976000
REACTOME SENSORY PERCEPTION OF TASTE	47	4.24e-01	6.75e-02	0.976000
REACTOME RHOD GTPASE CYCLE	49	4.24e-01	6.60e-02	0.976000
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	4.27e-01	-1.00e-01	0.978000
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	4.27e-01	-3.04e-02	0.978000
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	4.29e-01	1.22e-01	0.978000
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	4.29e-01	9.74e-02	0.978000
REACTOME ALPHA DEFENSINS	6	4.29e-01	-1.86e-01	0.978000
REACTOME SIGNALING BY FGFR	85	4.31e-01	4.94e-02	0.978000
REACTOME XENOBIOTICS	22	4.31e-01	9.69e-02	0.978000
REACTOME TIGHT JUNCTION INTERACTIONS	29	4.32e-01	-8.44e-02	0.978000
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	4.33e-01	1.07e-01	0.978000
REACTOME KINESINS	59	4.38e-01	-5.84e-02	0.978000
REACTOME SIGNALING BY EGFR	49	4.38e-01	6.40e-02	0.978000
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	4.38e-01	-1.29e-01	0.978000
REACTOME DISEASES OF BASE EXCISION REPAIR	5	4.38e-01	-2.00e-01	0.978000
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	4.39e-01	5.72e-02	0.978000
REACTOME DEGRADATION OF DVL	56	4.40e-01	5.96e-02	0.978000
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	4.41e-01	1.34e-01	0.978000
REACTOME SIGNALING BY ALK	26	4.43e-01	8.69e-02	0.978000
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	4.45e-01	-1.56e-01	0.978000
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	4.46e-01	1.56e-01	0.978000
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	4.46e-01	-1.18e-01	0.978000
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	4.46e-01	-1.14e-01	0.978000
REACTOME PLATELET HOMEOSTASIS	85	4.48e-01	-4.77e-02	0.978000
REACTOME ION HOMEOSTASIS	52	4.49e-01	6.07e-02	0.978000
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	4.49e-01	-8.41e-02	0.978000
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	4.50e-01	-7.98e-02	0.978000
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	4.50e-01	4.98e-02	0.978000
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	4.50e-01	1.21e-01	0.978000
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	4.50e-01	1.45e-01	0.978000
REACTOME DIGESTION OF DIETARY LIPID	7	4.53e-01	1.64e-01	0.978000
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	4.53e-01	-1.05e-01	0.978000
REACTOME TELOMERE MAINTENANCE	106	4.54e-01	-4.21e-02	0.978000
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	4.55e-01	1.63e-01	0.978000
REACTOME INTEGRIN SIGNALING	27	4.55e-01	8.31e-02	0.978000
REACTOME P38MAPK EVENTS	13	4.57e-01	-1.19e-01	0.978000
REACTOME TRYPTOPHAN CATABOLISM	14	4.58e-01	-1.15e-01	0.978000
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	4.58e-01	-1.52e-01	0.978000
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	4.58e-01	1.11e-01	0.978000
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	4.59e-01	-1.21e-02	0.978000
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	4.59e-01	-1.91e-01	0.978000
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	4.59e-01	4.59e-02	0.978000
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	4.59e-01	-9.80e-02	0.978000
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	4.60e-01	3.56e-02	0.978000
REACTOME NEUREXINS AND NEUROLIGINS	51	4.61e-01	-5.96e-02	0.978000
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	4.62e-01	-9.26e-02	0.978000
REACTOME NOD1 2 SIGNALING PATHWAY	33	4.63e-01	-7.38e-02	0.978000
REACTOME IRS ACTIVATION	5	4.63e-01	-1.90e-01	0.978000
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	4.64e-01	-9.71e-02	0.978000
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	4.65e-01	1.41e-01	0.978000
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	4.66e-01	1.33e-01	0.978000
REACTOME EXTENSION OF TELOMERES	49	4.66e-01	6.02e-02	0.978000
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	4.67e-01	1.49e-01	0.978000
REACTOME ATTACHMENT AND ENTRY	16	4.67e-01	-1.05e-01	0.978000
REACTOME MYOGENESIS	29	4.69e-01	-7.76e-02	0.978000
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	4.70e-01	-1.26e-01	0.978000
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	4.70e-01	1.87e-01	0.978000
REACTOME SIGNALING BY HEDGEHOG	148	4.70e-01	-3.44e-02	0.978000
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	4.70e-01	-1.47e-01	0.978000
REACTOME REGULATION OF INSULIN SECRETION	77	4.70e-01	-4.76e-02	0.978000
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	4.71e-01	-1.57e-01	0.978000
REACTOME DISEASES OF IMMUNE SYSTEM	29	4.72e-01	-7.72e-02	0.978000
REACTOME MAPK FAMILY SIGNALING CASCADES	314	4.73e-01	-2.35e-02	0.978000
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	4.73e-01	-1.15e-01	0.978000
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	4.74e-01	1.19e-01	0.978000
REACTOME SYNTHESIS OF GDP MANNOSE	5	4.74e-01	-1.85e-01	0.978000
REACTOME MRNA CAPPING	28	4.75e-01	7.80e-02	0.978000
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	4.75e-01	3.17e-02	0.978000
REACTOME METABOLISM OF NUCLEOTIDES	94	4.76e-01	-4.26e-02	0.978000
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	4.77e-01	1.55e-01	0.978000
REACTOME INTERFERON SIGNALING	193	4.77e-01	2.97e-02	0.978000
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	4.77e-01	-6.84e-02	0.978000
REACTOME TP53 REGULATES METABOLIC GENES	81	4.78e-01	-4.56e-02	0.978000
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	4.79e-01	-1.67e-01	0.978000
REACTOME SMOOTH MUSCLE CONTRACTION	43	4.79e-01	6.24e-02	0.978000
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	4.80e-01	-4.35e-02	0.978000
REACTOME ACYL CHAIN REMODELLING OF PI	17	4.81e-01	-9.88e-02	0.978000
REACTOME PURINE SALVAGE	12	4.81e-01	-1.17e-01	0.978000
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	4.81e-01	3.96e-02	0.978000
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	4.82e-01	6.51e-02	0.978000
REACTOME SIGNALING BY NODAL	20	4.82e-01	9.08e-02	0.978000
REACTOME RHOA GTPASE CYCLE	142	4.82e-01	3.41e-02	0.978000
REACTOME ANDROGEN BIOSYNTHESIS	11	4.83e-01	-1.22e-01	0.978000
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	4.83e-01	-1.43e-01	0.978000
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	4.83e-01	-7.53e-02	0.978000
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	4.83e-01	-7.94e-02	0.978000
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	4.84e-01	1.28e-01	0.978000
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	4.84e-01	1.08e-01	0.978000
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	4.84e-01	7.37e-02	0.978000
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	4.85e-01	1.43e-01	0.978000
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	4.86e-01	-5.00e-02	0.978000
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	4.86e-01	-5.43e-02	0.978000
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	4.86e-01	-7.61e-02	0.978000
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	4.86e-01	-1.27e-01	0.978000
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	4.87e-01	-5.46e-02	0.978000
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	4.88e-01	1.64e-01	0.978000
REACTOME COBALAMIN CBL METABOLISM	7	4.88e-01	-1.51e-01	0.978000
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	4.90e-01	6.23e-02	0.978000
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	4.91e-01	-1.20e-01	0.978000
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	4.91e-01	1.10e-01	0.978000
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	4.91e-01	8.30e-02	0.978000
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	4.92e-01	-8.28e-02	0.978000
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	4.93e-01	-2.37e-02	0.978000
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	4.93e-01	-7.48e-02	0.978000
REACTOME RAC3 GTPASE CYCLE	85	4.93e-01	4.30e-02	0.978000
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	4.94e-01	-3.92e-02	0.978000
REACTOME REGULATION OF IFNG SIGNALING	14	4.95e-01	-1.05e-01	0.978000
REACTOME ADAPTIVE IMMUNE SYSTEM	729	4.95e-01	1.48e-02	0.978000
REACTOME ONCOGENIC MAPK SIGNALING	79	4.96e-01	-4.43e-02	0.978000
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	4.96e-01	4.43e-02	0.978000
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	4.97e-01	9.01e-02	0.978000
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	4.97e-01	6.06e-02	0.978000
REACTOME LAMININ INTERACTIONS	28	4.98e-01	-7.41e-02	0.978000
REACTOME CREB3 FACTORS ACTIVATE GENES	8	4.98e-01	1.38e-01	0.978000
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	4.98e-01	-9.50e-02	0.978000
REACTOME CHOLESTEROL BIOSYNTHESIS	25	4.98e-01	-7.82e-02	0.978000
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	4.99e-01	-4.10e-02	0.978000
REACTOME NRCAM INTERACTIONS	6	4.99e-01	-1.59e-01	0.978000
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	5.00e-01	-1.59e-01	0.978000
REACTOME REGULATED NECROSIS	57	5.00e-01	5.17e-02	0.978000
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	5.00e-01	-1.47e-01	0.978000
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	5.00e-01	-1.12e-01	0.978000
REACTOME VLDL ASSEMBLY	5	5.01e-01	-1.74e-01	0.978000
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	5.01e-01	-1.00e-01	0.978000
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	5.01e-01	1.47e-01	0.978000
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	5.01e-01	8.11e-02	0.978000
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	5.01e-01	-1.04e-01	0.978000
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	5.01e-01	1.29e-01	0.978000
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	5.02e-01	4.85e-02	0.978000
REACTOME ANCHORING FIBRIL FORMATION	13	5.03e-01	-1.07e-01	0.978000
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	5.03e-01	6.74e-02	0.978000
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	5.03e-01	-1.58e-01	0.978000
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	5.04e-01	-9.66e-02	0.978000
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	5.04e-01	-1.73e-01	0.978000
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	5.05e-01	1.57e-01	0.979000
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	5.07e-01	1.16e-01	0.980000
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	5.07e-01	6.48e-02	0.980000
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	5.08e-01	1.10e-01	0.980000
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	5.08e-01	1.35e-01	0.980000
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	5.09e-01	9.54e-02	0.980000
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	5.11e-01	2.99e-02	0.983000
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	5.12e-01	-5.65e-02	0.983000
REACTOME ESR MEDIATED SIGNALING	210	5.12e-01	-2.63e-02	0.983000
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	5.13e-01	-1.26e-01	0.985000
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	5.14e-01	-1.01e-01	0.986000
REACTOME GLYCOLYSIS	70	5.16e-01	-4.49e-02	0.988000
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	5.18e-01	4.71e-02	0.988000
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	5.18e-01	-9.99e-02	0.988000
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	5.19e-01	1.41e-01	0.988000
REACTOME ESTROGEN BIOSYNTHESIS	6	5.19e-01	1.52e-01	0.988000
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	5.19e-01	7.30e-02	0.988000
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	5.22e-01	-6.26e-02	0.991000
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	5.23e-01	-8.95e-02	0.992000
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	5.23e-01	-9.85e-02	0.992000
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	5.24e-01	1.11e-01	0.992000
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	5.25e-01	-3.11e-02	0.992000
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	5.27e-01	1.16e-01	0.992000
REACTOME INTERLEUKIN 37 SIGNALING	20	5.27e-01	-8.17e-02	0.992000
REACTOME SYNTHESIS OF PG	8	5.28e-01	-1.29e-01	0.992000
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	5.28e-01	7.44e-02	0.992000
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	5.28e-01	-9.11e-02	0.992000
REACTOME CELL CYCLE MITOTIC	539	5.28e-01	1.59e-02	0.992000
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	5.28e-01	8.58e-02	0.992000
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	5.30e-01	1.01e-01	0.992000
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	5.30e-01	-1.09e-01	0.992000
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	5.32e-01	-6.95e-02	0.992000
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	5.34e-01	-7.84e-02	0.992000
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	5.34e-01	-5.08e-02	0.992000
REACTOME PEXOPHAGY	11	5.35e-01	-1.08e-01	0.992000
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	5.35e-01	1.35e-01	0.992000
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	5.35e-01	1.35e-01	0.992000
REACTOME ALPHA OXIDATION OF PHYTANATE	6	5.36e-01	1.46e-01	0.992000
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	5.36e-01	4.92e-02	0.992000
REACTOME SHC MEDIATED CASCADE FGFR4	19	5.36e-01	8.19e-02	0.992000
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	5.38e-01	1.19e-01	0.992000
REACTOME RORA ACTIVATES GENE EXPRESSION	17	5.39e-01	8.61e-02	0.992000
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	5.40e-01	-1.12e-01	0.992000
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	5.41e-01	1.34e-01	0.992000
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	5.41e-01	9.78e-02	0.992000
REACTOME GAB1 SIGNALOSOME	17	5.42e-01	8.55e-02	0.992000
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	5.42e-01	3.22e-02	0.992000
REACTOME CALCINEURIN ACTIVATES NFAT	9	5.42e-01	-1.17e-01	0.992000
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	5.43e-01	7.68e-02	0.992000
REACTOME L1CAM INTERACTIONS	112	5.44e-01	-3.32e-02	0.992000
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	5.44e-01	-3.18e-02	0.992000
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	5.44e-01	7.30e-02	0.992000
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	5.44e-01	-8.03e-02	0.992000
REACTOME REGULATION OF TP53 ACTIVITY	156	5.46e-01	2.80e-02	0.992000
REACTOME TBC RABGAPS	40	5.47e-01	5.50e-02	0.992000
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	5.47e-01	-6.69e-02	0.992000
REACTOME G ALPHA I SIGNALLING EVENTS	304	5.48e-01	-2.01e-02	0.992000
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	5.48e-01	-7.23e-02	0.992000
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	5.49e-01	-1.55e-01	0.992000
REACTOME MELANIN BIOSYNTHESIS	5	5.49e-01	-1.55e-01	0.992000
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	5.49e-01	-1.55e-01	0.992000
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	5.50e-01	-4.66e-02	0.992000
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	5.51e-01	1.15e-01	0.992000
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	5.52e-01	-1.04e-01	0.992000
REACTOME METALLOTHIONEINS BIND METALS	11	5.52e-01	-1.04e-01	0.992000
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	5.52e-01	4.59e-02	0.992000
REACTOME VESICLE MEDIATED TRANSPORT	642	5.53e-01	1.37e-02	0.992000
REACTOME PROCESSING OF SMDT1	16	5.53e-01	8.56e-02	0.992000
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	5.54e-01	3.98e-02	0.992000
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	5.55e-01	4.61e-02	0.992000
REACTOME P75NTR SIGNALS VIA NF KB	15	5.56e-01	-8.79e-02	0.992000
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	5.56e-01	7.09e-02	0.992000
REACTOME SIGNALING BY NOTCH3	48	5.56e-01	-4.91e-02	0.992000
REACTOME REGULATION OF SIGNALING BY CBL	22	5.57e-01	7.23e-02	0.992000
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	5.58e-01	-9.38e-02	0.992000
REACTOME SELECTIVE AUTOPHAGY	79	5.59e-01	3.80e-02	0.992000
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	5.59e-01	1.12e-01	0.992000
REACTOME DUAL INCISION IN TC NER	63	5.60e-01	4.25e-02	0.992000
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	5.60e-01	1.12e-01	0.992000
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	5.60e-01	-7.53e-02	0.992000
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	5.61e-01	-6.86e-02	0.992000
REACTOME CARGO CONCENTRATION IN THE ER	32	5.61e-01	5.94e-02	0.992000
REACTOME MET ACTIVATES RAP1 AND RAC1	11	5.63e-01	1.01e-01	0.992000
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	5.64e-01	7.11e-02	0.992000
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	5.64e-01	8.33e-02	0.992000
REACTOME PYROPTOSIS	27	5.65e-01	-6.40e-02	0.992000
REACTOME OPSINS	7	5.65e-01	-1.26e-01	0.992000
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	5.66e-01	6.63e-02	0.992000
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	5.66e-01	6.05e-02	0.992000
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	5.67e-01	6.15e-02	0.992000
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	5.67e-01	-3.44e-02	0.992000
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	5.67e-01	-9.97e-02	0.992000
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	5.70e-01	4.60e-02	0.993000
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	5.70e-01	1.16e-01	0.993000
REACTOME DARPP 32 EVENTS	24	5.70e-01	6.69e-02	0.993000
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	5.71e-01	8.75e-02	0.993000
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	5.72e-01	-1.46e-01	0.993000
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	5.74e-01	6.14e-02	0.993000
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	5.75e-01	-8.66e-02	0.993000
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	5.75e-01	-4.22e-02	0.993000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	5.76e-01	-1.44e-01	0.993000
REACTOME CIRCADIAN CLOCK	68	5.77e-01	-3.91e-02	0.993000
REACTOME G2 PHASE	5	5.78e-01	1.44e-01	0.993000
REACTOME HEMOSTASIS	591	5.79e-01	1.33e-02	0.993000
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	5.80e-01	1.01e-01	0.993000
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	5.80e-01	3.64e-02	0.993000
REACTOME PYRUVATE METABOLISM	29	5.80e-01	-5.93e-02	0.993000
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	5.81e-01	-1.20e-01	0.993000
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	5.83e-01	-2.88e-02	0.993000
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	5.83e-01	-5.69e-02	0.993000
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	5.84e-01	-5.14e-02	0.993000
REACTOME ONCOGENE INDUCED SENESCENCE	35	5.84e-01	-5.35e-02	0.993000
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	5.84e-01	-1.12e-01	0.993000
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	5.85e-01	-6.89e-02	0.993000
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	5.85e-01	-9.11e-02	0.993000
REACTOME MAP2K AND MAPK ACTIVATION	38	5.85e-01	-5.12e-02	0.993000
REACTOME AZATHIOPRINE ADME	22	5.85e-01	6.73e-02	0.993000
REACTOME NICOTINAMIDE SALVAGING	19	5.85e-01	-7.23e-02	0.993000
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	5.85e-01	1.05e-01	0.993000
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	5.85e-01	-1.41e-01	0.993000
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	5.87e-01	-9.47e-02	0.993000
REACTOME SLC TRANSPORTER DISORDERS	94	5.87e-01	-3.24e-02	0.993000
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	5.87e-01	6.85e-02	0.993000
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	5.89e-01	-4.87e-02	0.993000
REACTOME NEF AND SIGNAL TRANSDUCTION	8	5.89e-01	-1.10e-01	0.993000
REACTOME BETA DEFENSINS	27	5.90e-01	5.99e-02	0.993000
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	5.91e-01	6.94e-02	0.993000
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	5.92e-01	6.93e-02	0.993000
REACTOME MET ACTIVATES PTK2 SIGNALING	30	5.92e-01	5.65e-02	0.993000
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	5.93e-01	4.82e-02	0.993000
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	5.93e-01	-2.45e-02	0.993000
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	5.93e-01	-5.29e-02	0.993000
REACTOME SIGNAL ATTENUATION	10	5.94e-01	9.74e-02	0.993000
REACTOME RHOJ GTPASE CYCLE	51	5.95e-01	-4.30e-02	0.993000
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	5.95e-01	-1.09e-01	0.993000
REACTOME METABOLISM OF COFACTORS	19	5.95e-01	7.04e-02	0.993000
REACTOME SIGNALING BY NOTCH2	32	5.96e-01	-5.42e-02	0.993000
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	5.96e-01	7.65e-02	0.993000
REACTOME TRANSLESION SYNTHESIS BY POLH	19	5.98e-01	6.99e-02	0.993000
REACTOME RHO GTPASES ACTIVATE KTN1	11	5.98e-01	-9.17e-02	0.993000
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	5.98e-01	-5.30e-02	0.993000
REACTOME FORMATION OF APOPTOSOME	10	5.99e-01	-9.61e-02	0.993000
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	6.00e-01	6.95e-02	0.993000
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	6.01e-01	3.51e-02	0.993000
REACTOME SULFUR AMINO ACID METABOLISM	27	6.01e-01	5.81e-02	0.993000
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	6.01e-01	-3.02e-02	0.993000
REACTOME REGULATION BY C FLIP	11	6.02e-01	9.09e-02	0.993000
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	6.02e-01	-8.36e-02	0.993000
REACTOME PI 3K CASCADE FGFR1	21	6.02e-01	-6.57e-02	0.993000
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	6.03e-01	1.23e-01	0.993000
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	6.06e-01	1.13e-01	0.993000
REACTOME CREB PHOSPHORYLATION	6	6.06e-01	1.22e-01	0.993000
REACTOME BASIGIN INTERACTIONS	24	6.06e-01	-6.08e-02	0.993000
REACTOME REPRESSION OF WNT TARGET GENES	14	6.08e-01	7.91e-02	0.993000
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	6.10e-01	-3.28e-02	0.993000
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	6.11e-01	-3.21e-02	0.993000
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	6.11e-01	5.12e-02	0.993000
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	6.11e-01	-9.79e-02	0.993000
REACTOME ORGANIC ANION TRANSPORTERS	10	6.11e-01	-9.28e-02	0.993000
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	6.12e-01	4.19e-02	0.993000
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	6.13e-01	8.11e-02	0.993000
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	6.13e-01	-7.30e-02	0.993000
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	6.14e-01	1.13e-02	0.993000
REACTOME NUCLEOTIDE EXCISION REPAIR	107	6.14e-01	2.82e-02	0.993000
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	6.15e-01	-5.06e-02	0.993000
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	6.15e-01	-7.76e-02	0.993000
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	6.16e-01	-8.72e-02	0.993000
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	6.17e-01	1.18e-01	0.993000
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	6.21e-01	-6.93e-02	0.993000
REACTOME MUCOPOLYSACCHARIDOSES	10	6.21e-01	9.04e-02	0.993000
REACTOME ERKS ARE INACTIVATED	13	6.22e-01	-7.90e-02	0.993000
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	6.22e-01	9.49e-02	0.993000
REACTOME HDL ASSEMBLY	8	6.22e-01	1.01e-01	0.993000
REACTOME PERK REGULATES GENE EXPRESSION	31	6.24e-01	-5.09e-02	0.993000
REACTOME G PROTEIN ACTIVATION	24	6.24e-01	-5.78e-02	0.993000
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	6.25e-01	-5.90e-02	0.993000
REACTOME FORMATION OF PARAXIAL MESODERM	22	6.25e-01	-6.02e-02	0.993000
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	6.25e-01	-4.99e-02	0.993000
REACTOME TYROSINE CATABOLISM	5	6.26e-01	1.26e-01	0.993000
REACTOME RHO GTPASES ACTIVATE PAKS	19	6.29e-01	-6.40e-02	0.993000
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	6.29e-01	2.94e-02	0.993000
REACTOME PHASE 0 RAPID DEPOLARISATION	31	6.29e-01	5.01e-02	0.993000
REACTOME SIGNAL TRANSDUCTION BY L1	20	6.30e-01	-6.22e-02	0.993000
REACTOME RHOC GTPASE CYCLE	71	6.30e-01	3.30e-02	0.993000
REACTOME THYROXINE BIOSYNTHESIS	10	6.30e-01	-8.79e-02	0.993000
REACTOME NICOTINATE METABOLISM	31	6.31e-01	4.99e-02	0.993000
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	6.31e-01	-3.56e-02	0.993000
REACTOME CILIUM ASSEMBLY	190	6.31e-01	-2.02e-02	0.993000
REACTOME CA2 PATHWAY	62	6.31e-01	3.53e-02	0.993000
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	6.31e-01	-8.36e-02	0.993000
REACTOME MET INTERACTS WITH TNS PROTEINS	5	6.32e-01	-1.24e-01	0.993000
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	6.32e-01	6.91e-02	0.993000
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	6.35e-01	-6.29e-02	0.993000
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	6.36e-01	-9.12e-02	0.993000
REACTOME CELL JUNCTION ORGANIZATION	89	6.36e-01	-2.90e-02	0.993000
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	6.36e-01	1.06e-02	0.993000
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	6.37e-01	-4.21e-02	0.993000
REACTOME ZINC TRANSPORTERS	15	6.38e-01	-7.01e-02	0.993000
REACTOME LEISHMANIA INFECTION	156	6.39e-01	-2.18e-02	0.993000
REACTOME RET SIGNALING	40	6.39e-01	4.29e-02	0.993000
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	6.40e-01	5.41e-02	0.993000
REACTOME SIGNALING BY BMP	27	6.40e-01	-5.20e-02	0.993000
REACTOME PROPIONYL COA CATABOLISM	5	6.41e-01	-1.20e-01	0.993000
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	6.41e-01	-9.52e-02	0.993000
REACTOME VXPX CARGO TARGETING TO CILIUM	20	6.42e-01	6.01e-02	0.993000
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	6.43e-01	-6.69e-02	0.993000
REACTOME SIGNALING BY ACTIVIN	15	6.43e-01	6.91e-02	0.993000
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	6.44e-01	2.38e-02	0.993000
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	6.44e-01	4.80e-02	0.993000
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	6.44e-01	-2.56e-02	0.993000
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	6.44e-01	3.74e-02	0.993000
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	6.45e-01	-7.12e-02	0.993000
REACTOME KEAP1 NFE2L2 PATHWAY	104	6.45e-01	2.62e-02	0.993000
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	6.45e-01	9.41e-02	0.993000
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	6.45e-01	5.43e-02	0.993000
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	6.48e-01	5.63e-02	0.993000
REACTOME PROTEIN UBIQUITINATION	76	6.49e-01	-3.02e-02	0.993000
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	6.51e-01	1.58e-02	0.993000
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	6.51e-01	-1.17e-01	0.993000
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	6.51e-01	8.26e-02	0.993000
REACTOME PCP CE PATHWAY	91	6.51e-01	2.74e-02	0.993000
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	6.52e-01	-5.56e-02	0.993000
REACTOME RELAXIN RECEPTORS	8	6.52e-01	9.19e-02	0.993000
REACTOME RHO GTPASES ACTIVATE FORMINS	136	6.54e-01	2.23e-02	0.993000
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	6.55e-01	-4.57e-02	0.993000
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	6.55e-01	-4.43e-02	0.993000
REACTOME INDUCTION OF CELL CELL FUSION	12	6.55e-01	-7.45e-02	0.993000
REACTOME PLATELET SENSITIZATION BY LDL	17	6.56e-01	-6.24e-02	0.993000
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	6.57e-01	-1.36e-02	0.993000
REACTOME DAG AND IP3 SIGNALING	40	6.57e-01	4.05e-02	0.993000
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	6.58e-01	-5.12e-02	0.993000
REACTOME UBIQUINOL BIOSYNTHESIS	8	6.58e-01	9.04e-02	0.993000
REACTOME RHOH GTPASE CYCLE	37	6.58e-01	4.21e-02	0.993000
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	6.58e-01	1.26e-02	0.993000
REACTOME VITAMIN C ASCORBATE METABOLISM	8	6.58e-01	-9.03e-02	0.993000
REACTOME OTHER INTERLEUKIN SIGNALING	24	6.59e-01	5.20e-02	0.993000
REACTOME SIALIC ACID METABOLISM	33	6.59e-01	4.43e-02	0.993000
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	6.60e-01	-2.88e-02	0.993000
REACTOME COHESIN LOADING ONTO CHROMATIN	8	6.60e-01	8.97e-02	0.993000
REACTOME METABOLISM OF POLYAMINES	56	6.61e-01	3.38e-02	0.993000
REACTOME SIGNALING BY FGFR3	39	6.63e-01	4.04e-02	0.993000
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	6.64e-01	4.03e-02	0.993000
REACTOME REPRODUCTION	136	6.64e-01	2.15e-02	0.993000
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	6.65e-01	-6.68e-02	0.993000
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	6.66e-01	6.04e-02	0.993000
REACTOME SIGNALING BY RNF43 MUTANTS	8	6.67e-01	-8.79e-02	0.993000
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	6.68e-01	-1.01e-01	0.993000
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	6.70e-01	9.31e-02	0.993000
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	6.70e-01	-2.49e-02	0.993000
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	6.71e-01	-7.41e-02	0.993000
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	6.71e-01	-9.26e-02	0.993000
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	6.72e-01	-7.74e-02	0.993000
REACTOME GLYCOGEN STORAGE DISEASES	15	6.72e-01	-6.32e-02	0.993000
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	6.72e-01	3.96e-02	0.993000
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	6.73e-01	-3.91e-02	0.993000
REACTOME MITOTIC PROPHASE	134	6.73e-01	-2.11e-02	0.993000
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	6.73e-01	-6.09e-02	0.993000
REACTOME CHYLOMICRON CLEARANCE	5	6.74e-01	-1.09e-01	0.993000
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	6.74e-01	2.07e-02	0.993000
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	6.75e-01	-8.57e-02	0.993000
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	6.77e-01	-6.01e-02	0.993000
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	6.78e-01	6.20e-02	0.993000
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	6.79e-01	4.99e-02	0.993000
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	6.79e-01	7.96e-02	0.993000
REACTOME INTERLEUKIN 7 SIGNALING	31	6.80e-01	-4.28e-02	0.993000
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	6.80e-01	-9.72e-02	0.993000
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	6.80e-01	-3.34e-02	0.993000
REACTOME SIGNALING BY WNT IN CANCER	32	6.82e-01	-4.18e-02	0.993000
REACTOME PI3K AKT SIGNALING IN CANCER	103	6.83e-01	-2.33e-02	0.993000
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	6.83e-01	-5.72e-02	0.993000
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	6.83e-01	-7.11e-02	0.993000
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	6.83e-01	-5.27e-02	0.993000
REACTOME INTERLEUKIN 35 SIGNALLING	12	6.84e-01	-6.79e-02	0.993000
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	6.85e-01	-4.69e-02	0.993000
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	6.86e-01	-3.53e-02	0.993000
REACTOME PHOSPHORYLATION OF EMI1	6	6.87e-01	9.49e-02	0.993000
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	6.88e-01	5.18e-02	0.993000
REACTOME METABOLISM OF FOLATE AND PTERINES	17	6.90e-01	-5.60e-02	0.993000
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	6.91e-01	2.18e-02	0.993000
REACTOME ALK MUTANTS BIND TKIS	12	6.91e-01	6.62e-02	0.993000
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	6.93e-01	4.04e-02	0.993000
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	6.93e-01	9.30e-02	0.993000
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	6.93e-01	5.88e-02	0.993000
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	6.95e-01	5.67e-02	0.993000
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	6.95e-01	5.49e-02	0.993000
REACTOME SYNTHESIS OF PI	5	6.97e-01	-1.00e-01	0.993000
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	6.98e-01	3.96e-02	0.993000
REACTOME BIOSYNTHESIS OF MARESINS	8	6.98e-01	-7.92e-02	0.993000
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	6.99e-01	-5.41e-02	0.993000
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	6.99e-01	-4.14e-02	0.993000
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	7.00e-01	7.43e-02	0.993000
REACTOME ETHANOL OXIDATION	12	7.00e-01	6.42e-02	0.993000
REACTOME HEME BIOSYNTHESIS	13	7.01e-01	-6.16e-02	0.993000
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	7.01e-01	-4.34e-02	0.993000
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	7.02e-01	3.85e-02	0.993000
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	7.04e-01	-4.68e-02	0.993000
REACTOME FRUCTOSE METABOLISM	7	7.04e-01	8.29e-02	0.993000
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	7.04e-01	-3.42e-02	0.993000
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	7.05e-01	-9.77e-02	0.993000
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	7.05e-01	-6.90e-02	0.993000
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	7.05e-01	5.64e-02	0.993000
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	7.06e-01	-4.75e-02	0.993000
REACTOME SIGNALING BY INTERLEUKINS	444	7.07e-01	1.04e-02	0.993000
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	7.07e-01	7.25e-02	0.993000
REACTOME SIGNALLING TO ERKS	34	7.07e-01	-3.73e-02	0.993000
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	7.07e-01	2.48e-02	0.993000
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	7.07e-01	-1.99e-02	0.993000
REACTOME RHO GTPASE EFFECTORS	305	7.07e-01	-1.25e-02	0.993000
REACTOME DUAL INCISION IN GG NER	39	7.08e-01	3.47e-02	0.993000
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	7.08e-01	-1.86e-02	0.993000
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	7.09e-01	7.19e-02	0.993000
REACTOME INTERLEUKIN 1 SIGNALING	110	7.09e-01	2.06e-02	0.993000
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	7.10e-01	-3.28e-02	0.993000
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	7.11e-01	5.72e-02	0.993000
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	7.13e-01	-4.17e-02	0.993000
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	7.13e-01	-2.42e-02	0.993000
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	7.14e-01	-5.14e-02	0.993000
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	7.14e-01	8.00e-02	0.993000
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	7.14e-01	5.13e-02	0.993000
REACTOME PHOSPHORYLATION OF THE APC C	20	7.15e-01	4.71e-02	0.993000
REACTOME HOMOLOGY DIRECTED REPAIR	132	7.15e-01	1.84e-02	0.993000
REACTOME CHL1 INTERACTIONS	9	7.15e-01	7.02e-02	0.993000
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	7.16e-01	7.95e-02	0.993000
REACTOME PI 3K CASCADE FGFR3	17	7.19e-01	5.05e-02	0.993000
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	7.21e-01	-4.51e-02	0.993000
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	7.21e-01	-2.67e-02	0.993000
REACTOME RHO GTPASES ACTIVATE ROCKS	19	7.24e-01	4.67e-02	0.993000
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	7.25e-01	2.34e-02	0.993000
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	7.26e-01	2.78e-02	0.993000
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	7.27e-01	4.04e-02	0.993000
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	7.27e-01	-5.20e-02	0.993000
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	7.27e-01	6.07e-02	0.993000
REACTOME NEPHRIN FAMILY INTERACTIONS	22	7.28e-01	-4.28e-02	0.993000
REACTOME ATORVASTATIN ADME	9	7.29e-01	6.68e-02	0.993000
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	7.29e-01	-4.86e-02	0.993000
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	7.29e-01	2.45e-02	0.993000
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	7.29e-01	-2.50e-02	0.993000
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	7.30e-01	-4.58e-02	0.993000
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	7.31e-01	-6.63e-02	0.993000
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	7.31e-01	3.27e-02	0.993000
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	7.31e-01	-4.05e-02	0.993000
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	7.32e-01	-8.85e-02	0.993000
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	7.33e-01	-5.93e-02	0.993000
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	7.34e-01	2.37e-02	0.993000
REACTOME SOS MEDIATED SIGNALLING	7	7.34e-01	-7.42e-02	0.993000
REACTOME GLUCOSE METABOLISM	90	7.34e-01	2.07e-02	0.993000
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	7.34e-01	3.64e-02	0.993000
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	7.35e-01	3.22e-02	0.993000
REACTOME SODIUM PROTON EXCHANGERS	7	7.35e-01	7.39e-02	0.993000
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	7.35e-01	5.04e-02	0.993000
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	7.36e-01	1.99e-02	0.993000
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	7.37e-01	3.96e-02	0.993000
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	7.37e-01	7.90e-02	0.993000
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	7.38e-01	7.31e-02	0.993000
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	7.38e-01	4.22e-02	0.993000
REACTOME INTERFERON GAMMA SIGNALING	88	7.38e-01	-2.06e-02	0.993000
REACTOME GLUTATHIONE CONJUGATION	33	7.39e-01	3.35e-02	0.993000
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	7.39e-01	7.86e-02	0.993000
REACTOME HEME SIGNALING	47	7.39e-01	-2.81e-02	0.993000
REACTOME UREA CYCLE	9	7.39e-01	-6.40e-02	0.993000
REACTOME G0 AND EARLY G1	27	7.40e-01	-3.69e-02	0.993000
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	7.40e-01	-1.59e-02	0.993000
REACTOME HEDGEHOG OFF STATE	111	7.41e-01	-1.81e-02	0.993000
REACTOME RND1 GTPASE CYCLE	41	7.42e-01	2.98e-02	0.993000
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	7.42e-01	-6.72e-02	0.993000
REACTOME LIPOPHAGY	9	7.43e-01	6.32e-02	0.993000
REACTOME NGF STIMULATED TRANSCRIPTION	38	7.43e-01	-3.08e-02	0.993000
REACTOME PTK6 EXPRESSION	5	7.43e-01	-8.47e-02	0.993000
REACTOME TRNA PROCESSING	105	7.43e-01	1.85e-02	0.993000
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	7.44e-01	-3.51e-02	0.993000
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	7.46e-01	1.87e-02	0.993000
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	7.46e-01	-4.29e-02	0.993000
REACTOME METABOLISM OF STEROID HORMONES	35	7.47e-01	-3.15e-02	0.993000
REACTOME HDMS DEMETHYLATE HISTONES	40	7.47e-01	-2.94e-02	0.993000
REACTOME SYNTHESIS OF PE	13	7.48e-01	5.15e-02	0.993000
REACTOME GENE SILENCING BY RNA	133	7.48e-01	1.61e-02	0.993000
REACTOME STIMULI SENSING CHANNELS	100	7.48e-01	1.86e-02	0.993000
REACTOME SIGNALING BY FGFR4	40	7.50e-01	2.91e-02	0.993000
REACTOME INTERLEUKIN 36 PATHWAY	7	7.50e-01	-6.95e-02	0.993000
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	7.51e-01	4.45e-02	0.993000
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	7.51e-01	-4.58e-02	0.993000
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	7.51e-01	-3.40e-02	0.993000
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	7.51e-01	-4.09e-02	0.993000
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	7.52e-01	3.58e-02	0.993000
REACTOME AGGREPHAGY	42	7.53e-01	-2.81e-02	0.993000
REACTOME RHOU GTPASE CYCLE	37	7.54e-01	2.98e-02	0.993000
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	7.54e-01	-1.55e-02	0.993000
REACTOME INTERLEUKIN 17 SIGNALING	66	7.54e-01	-2.23e-02	0.993000
REACTOME CELL CELL COMMUNICATION	126	7.54e-01	-1.61e-02	0.993000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	7.55e-01	8.07e-02	0.993000
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	7.55e-01	-1.82e-02	0.993000
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	7.55e-01	-5.69e-02	0.993000
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	7.55e-01	-5.69e-02	0.993000
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	7.56e-01	2.20e-02	0.993000
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	7.56e-01	-8.03e-02	0.993000
REACTOME METAL ION SLC TRANSPORTERS	23	7.56e-01	-3.74e-02	0.993000
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	7.57e-01	8.00e-02	0.993000
REACTOME CARNITINE METABOLISM	13	7.57e-01	4.95e-02	0.993000
REACTOME TRANSPORT OF ORGANIC ANIONS	10	7.57e-01	5.64e-02	0.993000
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	7.58e-01	-2.97e-02	0.993000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	7.59e-01	5.89e-02	0.993000
REACTOME TRANSPORT OF SMALL MOLECULES	697	7.60e-01	6.78e-03	0.993000
REACTOME CYTOPROTECTION BY HMOX1	59	7.60e-01	2.29e-02	0.993000
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	7.61e-01	-5.86e-02	0.993000
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	7.61e-01	5.29e-02	0.993000
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	7.62e-01	3.19e-02	0.993000
REACTOME TRIGLYCERIDE METABOLISM	35	7.62e-01	2.96e-02	0.993000
REACTOME CRISTAE FORMATION	27	7.63e-01	3.35e-02	0.993000
REACTOME PHENYLALANINE METABOLISM	6	7.63e-01	-7.11e-02	0.993000
REACTOME CREATINE METABOLISM	9	7.64e-01	5.78e-02	0.993000
REACTOME LONG TERM POTENTIATION	22	7.65e-01	-3.68e-02	0.993000
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	7.66e-01	-4.06e-02	0.993000
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	7.66e-01	2.54e-02	0.993000
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	7.66e-01	4.96e-02	0.993000
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	7.66e-01	3.51e-02	0.993000
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	7.67e-01	-4.43e-02	0.993000
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	7.67e-01	1.81e-02	0.993000
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	7.67e-01	3.29e-02	0.993000
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	7.67e-01	-7.68e-03	0.993000
REACTOME M PHASE	398	7.67e-01	8.64e-03	0.993000
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	7.68e-01	-5.39e-02	0.993000
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	7.69e-01	1.80e-02	0.993000
REACTOME RHOF GTPASE CYCLE	40	7.71e-01	-2.65e-02	0.993000
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	7.72e-01	-5.06e-02	0.993000
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	7.72e-01	-6.33e-02	0.993000
REACTOME PTK6 REGULATES CELL CYCLE	6	7.72e-01	6.82e-02	0.993000
REACTOME SIGNAL AMPLIFICATION	33	7.74e-01	-2.89e-02	0.993000
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	7.75e-01	-3.02e-02	0.993000
REACTOME SERINE BIOSYNTHESIS	9	7.75e-01	5.51e-02	0.993000
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	7.77e-01	-4.73e-02	0.993000
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	7.80e-01	4.48e-02	0.993000
REACTOME IKBA VARIANT LEADS TO EDA ID	6	7.80e-01	-6.59e-02	0.993000
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	7.80e-01	3.90e-02	0.993000
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	7.81e-01	2.18e-02	0.993000
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	7.82e-01	-2.75e-02	0.993000
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	7.83e-01	1.75e-02	0.993000
REACTOME DNA REPLICATION PRE INITIATION	150	7.85e-01	1.29e-02	0.993000
REACTOME PI5P REGULATES TP53 ACETYLATION	9	7.85e-01	-5.25e-02	0.993000
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	7.87e-01	6.37e-02	0.993000
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	7.87e-01	6.98e-02	0.993000
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	7.87e-01	-4.03e-02	0.993000
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	7.87e-01	4.93e-02	0.993000
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	7.88e-01	2.56e-02	0.993000
REACTOME TRANSLESION SYNTHESIS BY POLK	17	7.88e-01	-3.76e-02	0.993000
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	7.89e-01	1.82e-02	0.993000
REACTOME TNF SIGNALING	54	7.90e-01	-2.09e-02	0.993000
REACTOME RETINOID CYCLE DISEASE EVENTS	11	7.90e-01	-4.63e-02	0.993000
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	7.91e-01	-6.84e-02	0.993000
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	7.92e-01	4.59e-02	0.993000
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	7.93e-01	-3.67e-02	0.993000
REACTOME MET PROMOTES CELL MOTILITY	41	7.93e-01	2.36e-02	0.993000
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	7.95e-01	6.72e-02	0.993000
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	7.95e-01	-3.28e-02	0.993000
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	7.95e-01	-3.28e-02	0.993000
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	7.96e-01	3.19e-02	0.993000
REACTOME ROBO RECEPTORS BIND AKAP5	9	7.96e-01	-4.99e-02	0.993000
REACTOME DIGESTION AND ABSORPTION	22	7.96e-01	-3.18e-02	0.993000
REACTOME LYSOSOME VESICLE BIOGENESIS	33	7.97e-01	2.58e-02	0.993000
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	7.99e-01	5.19e-02	0.993000
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	8.00e-01	-3.91e-02	0.993000
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	8.00e-01	1.62e-02	0.993000
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	8.01e-01	2.37e-02	0.993000
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	8.02e-01	-2.32e-02	0.993000
REACTOME KERATINIZATION	210	8.03e-01	-9.99e-03	0.993000
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	8.03e-01	4.79e-02	0.993000
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	8.03e-01	-4.55e-02	0.993000
REACTOME INTERLEUKIN 1 PROCESSING	9	8.03e-01	4.79e-02	0.993000
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	8.04e-01	3.98e-02	0.993000
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	8.05e-01	3.82e-02	0.993000
REACTOME GLUCONEOGENESIS	33	8.05e-01	-2.48e-02	0.993000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	8.06e-01	5.80e-02	0.993000
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	8.06e-01	4.27e-02	0.993000
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	8.07e-01	-2.89e-02	0.993000
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	8.07e-01	5.77e-02	0.993000
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	8.09e-01	2.33e-02	0.993000
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	8.09e-01	4.42e-02	0.993000
REACTOME NUCLEOTIDE SALVAGE	21	8.09e-01	3.05e-02	0.993000
REACTOME TRAIL SIGNALING	8	8.11e-01	4.89e-02	0.993000
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	8.12e-01	3.68e-02	0.993000
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	8.12e-01	-2.51e-02	0.993000
REACTOME UCH PROTEINASES	99	8.12e-01	1.38e-02	0.993000
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	8.13e-01	-2.50e-02	0.993000
REACTOME SIGNALING BY FGFR1	49	8.13e-01	-1.95e-02	0.993000
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	8.14e-01	6.09e-02	0.993000
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	8.14e-01	3.78e-02	0.993000
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	8.14e-01	-3.40e-02	0.993000
REACTOME ACTIVATION OF RAS IN B CELLS	5	8.15e-01	-6.04e-02	0.993000
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	8.16e-01	-3.47e-02	0.993000
REACTOME REGULATION OF RAS BY GAPS	66	8.16e-01	1.66e-02	0.993000
REACTOME SIGNALING BY NOTCH	234	8.17e-01	-8.81e-03	0.993000
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	8.18e-01	5.42e-02	0.993000
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	8.18e-01	4.20e-02	0.993000
REACTOME VISUAL PHOTOTRANSDUCTION	93	8.19e-01	-1.37e-02	0.993000
REACTOME HSF1 ACTIVATION	29	8.19e-01	2.46e-02	0.993000
REACTOME NETRIN 1 SIGNALING	49	8.19e-01	-1.88e-02	0.993000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	8.20e-01	5.88e-02	0.993000
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	8.20e-01	-2.32e-02	0.993000
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	8.23e-01	3.45e-02	0.993000
REACTOME DIGESTION	17	8.25e-01	3.10e-02	0.993000
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	8.25e-01	4.82e-02	0.993000
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	8.25e-01	1.77e-02	0.993000
REACTOME ASSEMBLY OF THE HIV VIRION	16	8.27e-01	-3.16e-02	0.993000
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	8.27e-01	-2.53e-02	0.993000
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	8.27e-01	-1.70e-02	0.993000
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	8.28e-01	3.62e-02	0.993000
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	8.28e-01	-5.60e-02	0.993000
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	8.28e-01	-3.04e-02	0.993000
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	8.29e-01	-3.77e-02	0.993000
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	8.29e-01	-4.72e-02	0.993000
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	8.29e-01	-2.40e-02	0.993000
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	8.29e-01	-2.60e-02	0.993000
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	8.30e-01	2.31e-02	0.993000
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	8.30e-01	-3.91e-02	0.993000
REACTOME RHOV GTPASE CYCLE	36	8.31e-01	-2.06e-02	0.993000
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	8.31e-01	3.42e-02	0.993000
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	8.33e-01	1.69e-02	0.993000
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	8.36e-01	-4.23e-02	0.993000
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	8.36e-01	-3.45e-02	0.993000
REACTOME REGULATION OF BACH1 ACTIVITY	11	8.37e-01	-3.58e-02	0.993000
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	8.37e-01	4.20e-02	0.993000
REACTOME SYNTHESIS OF LIPOXINS LX	6	8.37e-01	4.84e-02	0.993000
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	8.37e-01	-1.51e-02	0.993000
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	8.38e-01	3.93e-02	0.993000
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	8.43e-01	-5.13e-02	0.993000
REACTOME PROTEIN FOLDING	96	8.43e-01	1.17e-02	0.993000
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	8.43e-01	-2.09e-02	0.993000
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	8.44e-01	2.23e-02	0.993000
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	8.44e-01	-1.18e-02	0.993000
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	8.45e-01	3.27e-02	0.993000
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	8.45e-01	-4.60e-02	0.993000
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	8.46e-01	-1.98e-02	0.993000
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	8.46e-01	-5.00e-02	0.993000
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	8.49e-01	3.33e-02	0.993000
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	8.49e-01	3.17e-02	0.993000
REACTOME EPH EPHRIN SIGNALING	90	8.50e-01	1.16e-02	0.993000
REACTOME ACYL CHAIN REMODELLING OF PG	18	8.50e-01	2.58e-02	0.993000
REACTOME RHOB GTPASE CYCLE	67	8.51e-01	-1.33e-02	0.993000
REACTOME MITOTIC PROMETAPHASE	194	8.52e-01	7.76e-03	0.993000
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	8.52e-01	2.11e-02	0.993000
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	8.53e-01	-3.09e-02	0.993000
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	8.54e-01	-1.58e-02	0.993000
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	8.54e-01	-3.35e-02	0.993000
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	8.55e-01	3.34e-02	0.993000
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	8.55e-01	-8.38e-03	0.993000
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	8.55e-01	-4.30e-02	0.993000
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	8.55e-01	-2.15e-02	0.993000
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	8.56e-01	2.54e-02	0.993000
REACTOME RAS PROCESSING	22	8.57e-01	-2.22e-02	0.993000
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	8.57e-01	4.65e-02	0.993000
REACTOME MAPK1 ERK2 ACTIVATION	9	8.57e-01	3.46e-02	0.993000
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	8.58e-01	2.44e-02	0.993000
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	8.58e-01	-1.86e-02	0.993000
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	8.58e-01	-2.67e-02	0.993000
REACTOME DNA DAMAGE REVERSAL	8	8.58e-01	3.64e-02	0.993000
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	8.59e-01	-2.85e-02	0.993000
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	8.59e-01	9.30e-03	0.993000
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	8.62e-01	-3.02e-02	0.993000
REACTOME SIGNALING BY PDGF	57	8.63e-01	-1.32e-02	0.993000
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	8.63e-01	4.45e-02	0.993000
REACTOME DISSOLUTION OF FIBRIN CLOT	13	8.63e-01	2.76e-02	0.993000
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	8.63e-01	3.76e-02	0.993000
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	8.63e-01	-2.66e-02	0.993000
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	8.63e-01	1.42e-02	0.993000
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	8.63e-01	-1.73e-02	0.993000
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	8.64e-01	2.56e-02	0.993000
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	8.64e-01	1.65e-02	0.993000
REACTOME PROSTANOID LIGAND RECEPTORS	9	8.64e-01	3.29e-02	0.993000
REACTOME CHROMOSOME MAINTENANCE	130	8.66e-01	-8.56e-03	0.993000
REACTOME CHROMATIN MODIFYING ENZYMES	252	8.67e-01	-6.15e-03	0.993000
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	8.67e-01	-3.43e-02	0.993000
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	8.67e-01	2.22e-02	0.993000
REACTOME RIBAVIRIN ADME	11	8.67e-01	2.91e-02	0.993000
REACTOME CHYLOMICRON REMODELING	10	8.68e-01	3.04e-02	0.993000
REACTOME PI 3K CASCADE FGFR2	22	8.69e-01	-2.03e-02	0.993000
REACTOME SYNDECAN INTERACTIONS	26	8.70e-01	1.86e-02	0.993000
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	8.70e-01	-3.33e-02	0.993000
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	8.71e-01	3.82e-02	0.993000
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	8.72e-01	3.30e-02	0.993000
REACTOME LAGGING STRAND SYNTHESIS	19	8.73e-01	2.13e-02	0.993000
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	8.74e-01	4.11e-02	0.993000
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	8.74e-01	1.90e-02	0.993000
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	8.75e-01	8.31e-03	0.993000
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	8.75e-01	1.65e-02	0.993000
REACTOME PI 3K CASCADE FGFR4	19	8.76e-01	2.07e-02	0.993000
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	8.76e-01	-2.26e-02	0.993000
REACTOME RND3 GTPASE CYCLE	41	8.76e-01	1.40e-02	0.993000
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	8.76e-01	4.01e-02	0.993000
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	8.77e-01	2.59e-02	0.993000
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	8.77e-01	2.05e-02	0.993000
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	8.80e-01	-3.07e-02	0.993000
REACTOME DEFENSINS	33	8.81e-01	1.51e-02	0.993000
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	8.81e-01	1.32e-02	0.993000
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	8.82e-01	2.86e-02	0.993000
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	8.82e-01	1.23e-02	0.993000
REACTOME DNA DAMAGE BYPASS	47	8.82e-01	-1.25e-02	0.993000
REACTOME HYALURONAN METABOLISM	17	8.83e-01	2.07e-02	0.993000
REACTOME KERATAN SULFATE DEGRADATION	13	8.83e-01	2.36e-02	0.993000
REACTOME DNA REPLICATION	178	8.84e-01	-6.35e-03	0.993000
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	8.84e-01	-1.35e-02	0.993000
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	8.85e-01	-1.58e-02	0.993000
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	8.85e-01	-2.52e-02	0.993000
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	8.85e-01	-1.77e-02	0.993000
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	8.86e-01	-2.50e-02	0.993000
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	8.87e-01	-3.66e-02	0.993000
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	8.87e-01	2.12e-02	0.993000
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	8.88e-01	-1.69e-02	0.993000
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	8.89e-01	-3.05e-02	0.993000
REACTOME METABOLISM OF CARBOHYDRATES	279	8.89e-01	-4.85e-03	0.993000
REACTOME HS GAG DEGRADATION	19	8.89e-01	-1.85e-02	0.993000
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	8.91e-01	2.51e-02	0.993000
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	8.91e-01	1.98e-02	0.993000
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	8.91e-01	-1.92e-02	0.993000
REACTOME METHIONINE SALVAGE PATHWAY	6	8.92e-01	3.21e-02	0.993000
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	8.93e-01	-1.29e-02	0.993000
REACTOME SIGNALING BY ERBB4	57	8.93e-01	1.03e-02	0.993000
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	8.93e-01	1.69e-02	0.993000
REACTOME SYNTHESIS OF PC	27	8.93e-01	-1.49e-02	0.993000
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	8.94e-01	2.71e-02	0.993000
REACTOME ACTIVATION OF TRKA RECEPTORS	6	8.95e-01	-3.13e-02	0.993000
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	8.95e-01	1.75e-02	0.993000
REACTOME INTERLEUKIN 9 SIGNALING	7	8.95e-01	2.88e-02	0.993000
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	8.96e-01	-2.68e-02	0.993000
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	8.96e-01	3.09e-02	0.993000
REACTOME DISINHIBITION OF SNARE FORMATION	5	8.96e-01	-3.37e-02	0.993000
REACTOME INTERLEUKIN 27 SIGNALING	11	8.97e-01	2.26e-02	0.993000
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	8.97e-01	-2.65e-02	0.993000
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	8.97e-01	1.86e-02	0.993000
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	8.98e-01	2.15e-02	0.993000
REACTOME OPIOID SIGNALLING	89	8.98e-01	7.88e-03	0.993000
REACTOME SIGNALING BY RETINOIC ACID	41	9.00e-01	-1.13e-02	0.993000
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	9.01e-01	8.28e-03	0.993000
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	9.01e-01	1.41e-02	0.993000
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	9.02e-01	-2.38e-02	0.993000
REACTOME RAF ACTIVATION	33	9.02e-01	1.24e-02	0.993000
REACTOME SIGNALING BY ERBB2	50	9.03e-01	9.94e-03	0.993000
REACTOME RUNX3 REGULATES P14 ARF	10	9.03e-01	2.22e-02	0.993000
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	9.04e-01	-3.10e-02	0.993000
REACTOME ARMS MEDIATED ACTIVATION	7	9.05e-01	2.62e-02	0.993000
REACTOME RHO GTPASES ACTIVATE CIT	19	9.05e-01	-1.58e-02	0.993000
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	9.05e-01	-1.54e-02	0.993000
REACTOME IRS MEDIATED SIGNALLING	47	9.06e-01	9.91e-03	0.993000
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	9.07e-01	-1.11e-02	0.993000
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	9.08e-01	2.24e-02	0.993000
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	9.08e-01	8.76e-03	0.993000
REACTOME EGFR DOWNREGULATION	30	9.08e-01	1.21e-02	0.993000
REACTOME PARASITE INFECTION	57	9.08e-01	8.81e-03	0.993000
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	9.10e-01	1.75e-02	0.993000
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	9.10e-01	-1.96e-02	0.993000
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	9.10e-01	4.82e-03	0.993000
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	9.10e-01	2.90e-02	0.993000
REACTOME IRON UPTAKE AND TRANSPORT	56	9.11e-01	8.67e-03	0.993000
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	9.11e-01	-5.24e-03	0.993000
REACTOME CELL CELL JUNCTION ORGANIZATION	64	9.11e-01	-8.05e-03	0.993000
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	9.12e-01	7.09e-03	0.993000
REACTOME SIGNALING BY LEPTIN	11	9.12e-01	-1.92e-02	0.993000
REACTOME OAS ANTIVIRAL RESPONSE	8	9.13e-01	2.24e-02	0.993000
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	9.14e-01	-2.07e-02	0.993000
REACTOME INTERLEUKIN 2 SIGNALING	11	9.14e-01	1.87e-02	0.993000
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	9.15e-01	-2.76e-02	0.993000
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	9.15e-01	-1.54e-02	0.993000
REACTOME PI3K AKT ACTIVATION	9	9.15e-01	-2.04e-02	0.993000
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	9.16e-01	1.85e-02	0.993000
REACTOME ERBB2 REGULATES CELL MOTILITY	15	9.16e-01	-1.57e-02	0.993000
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	9.17e-01	-1.83e-02	0.993000
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	9.17e-01	-1.38e-02	0.993000
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	9.17e-01	-2.01e-02	0.993000
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	9.17e-01	-5.68e-03	0.993000
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	9.18e-01	5.52e-03	0.993000
REACTOME REGULATION OF PTEN LOCALIZATION	8	9.19e-01	2.09e-02	0.993000
REACTOME RHOQ GTPASE CYCLE	57	9.19e-01	-7.78e-03	0.993000
REACTOME DEATH RECEPTOR SIGNALING	143	9.20e-01	4.85e-03	0.993000
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	9.22e-01	-1.05e-02	0.993000
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	9.23e-01	1.44e-02	0.993000
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	9.23e-01	5.60e-03	0.993000
REACTOME SIGNALING BY VEGF	102	9.23e-01	-5.53e-03	0.993000
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	9.24e-01	-1.38e-02	0.993000
REACTOME PHOSPHOLIPID METABOLISM	201	9.24e-01	3.91e-03	0.993000
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	9.24e-01	-1.02e-02	0.993000
REACTOME SIGNALING BY PTK6	54	9.29e-01	-7.01e-03	0.993000
REACTOME INTERLEUKIN 10 SIGNALING	43	9.30e-01	-7.77e-03	0.993000
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	9.32e-01	-7.32e-03	0.993000
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	9.32e-01	-9.37e-03	0.993000
REACTOME FRUCTOSE CATABOLISM	5	9.32e-01	2.20e-02	0.993000
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	9.32e-01	-1.48e-02	0.993000
REACTOME MITOTIC G2 G2 M PHASES	194	9.32e-01	3.53e-03	0.993000
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	9.33e-01	1.83e-02	0.993000
REACTOME RAB REGULATION OF TRAFFICKING	110	9.34e-01	-4.57e-03	0.993000
REACTOME SHC MEDIATED CASCADE FGFR1	21	9.35e-01	-1.03e-02	0.993000
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	9.35e-01	9.61e-03	0.993000
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	9.36e-01	-1.76e-02	0.993000
REACTOME INTRAFLAGELLAR TRANSPORT	50	9.36e-01	-6.57e-03	0.993000
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	9.36e-01	1.19e-02	0.993000
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	9.37e-01	-5.76e-03	0.993000
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	9.37e-01	1.27e-02	0.993000
REACTOME CALNEXIN CALRETICULIN CYCLE	26	9.38e-01	-8.84e-03	0.993000
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	9.38e-01	-2.01e-02	0.993000
REACTOME MEMBRANE TRAFFICKING	603	9.38e-01	1.85e-03	0.993000
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	9.39e-01	6.22e-03	0.993000
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	9.39e-01	7.16e-03	0.993000
REACTOME HEDGEHOG ON STATE	85	9.39e-01	-4.77e-03	0.993000
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	9.40e-01	1.77e-02	0.993000
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	9.41e-01	3.07e-03	0.993000
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	9.41e-01	-3.17e-03	0.993000
REACTOME PREGNENOLONE BIOSYNTHESIS	12	9.41e-01	-1.24e-02	0.993000
REACTOME SENSORY PROCESSING OF SOUND	72	9.41e-01	-5.01e-03	0.993000
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	9.42e-01	1.33e-02	0.993000
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	9.43e-01	-7.86e-03	0.993000
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	9.43e-01	8.66e-03	0.993000
REACTOME CA DEPENDENT EVENTS	36	9.43e-01	6.91e-03	0.993000
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	9.43e-01	1.10e-02	0.993000
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	9.44e-01	7.60e-03	0.993000
REACTOME DNA REPAIR	321	9.45e-01	2.26e-03	0.993000
REACTOME DEUBIQUITINATION	260	9.46e-01	-2.46e-03	0.993000
REACTOME RA BIOSYNTHESIS PATHWAY	22	9.46e-01	8.29e-03	0.993000
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	9.47e-01	1.44e-02	0.993000
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	9.48e-01	-9.15e-03	0.993000
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	9.50e-01	-7.13e-03	0.993000
REACTOME ATTENUATION PHASE	27	9.51e-01	6.80e-03	0.993000
REACTOME INTERFERON ALPHA BETA SIGNALING	70	9.52e-01	4.19e-03	0.993000
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	9.52e-01	-6.95e-03	0.993000
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	9.52e-01	8.63e-03	0.993000
REACTOME JOSEPHIN DOMAIN DUBS	11	9.53e-01	1.02e-02	0.993000
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	9.54e-01	3.17e-03	0.993000
REACTOME RHOT1 GTPASE CYCLE	5	9.54e-01	1.47e-02	0.993000
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	9.55e-01	5.57e-03	0.993000
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	9.55e-01	-6.88e-03	0.993000
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	9.55e-01	3.75e-03	0.993000
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	9.56e-01	1.43e-02	0.993000
REACTOME GLYCOGEN METABOLISM	22	9.56e-01	6.84e-03	0.993000
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	9.56e-01	-3.69e-03	0.993000
REACTOME SIGNALING BY LRP5 MUTANTS	6	9.56e-01	-1.29e-02	0.993000
REACTOME PHASE 2 PLATEAU PHASE	14	9.58e-01	-8.13e-03	0.993000
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	9.59e-01	5.46e-03	0.993000
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	9.59e-01	4.11e-03	0.993000
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	9.59e-01	-3.28e-03	0.993000
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	9.61e-01	-7.64e-03	0.993000
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	9.61e-01	-6.22e-03	0.993000
REACTOME NEUROFASCIN INTERACTIONS	6	9.61e-01	1.14e-02	0.993000
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	9.63e-01	1.21e-02	0.993000
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	9.63e-01	-6.69e-03	0.993000
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	9.63e-01	-7.68e-03	0.993000
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	9.63e-01	5.53e-03	0.993000
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	9.64e-01	-9.31e-03	0.993000
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	9.64e-01	-8.20e-03	0.993000
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	9.66e-01	-4.09e-03	0.993000
REACTOME GAP JUNCTION DEGRADATION	12	9.66e-01	-7.06e-03	0.993000
REACTOME P75NTR REGULATES AXONOGENESIS	9	9.67e-01	-7.99e-03	0.993000
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	9.67e-01	-3.94e-03	0.993000
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	9.67e-01	9.65e-03	0.993000
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	9.69e-01	-6.32e-03	0.993000
REACTOME CHOLINE CATABOLISM	6	9.70e-01	-8.91e-03	0.993000
REACTOME LDL CLEARANCE	19	9.70e-01	-4.98e-03	0.993000
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	9.70e-01	-6.24e-03	0.993000
REACTOME ORGANIC CATION TRANSPORT	10	9.70e-01	6.82e-03	0.993000
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	9.70e-01	-4.59e-03	0.993000
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	9.71e-01	2.43e-03	0.993000
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	9.71e-01	-1.21e-03	0.993000
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	9.72e-01	5.28e-03	0.993000
REACTOME MIRO GTPASE CYCLE	8	9.72e-01	7.07e-03	0.993000
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	9.73e-01	-4.52e-03	0.993000
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	9.73e-01	-7.31e-03	0.993000
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	9.73e-01	-8.60e-03	0.993000
REACTOME CLEC7A DECTIN 1 SIGNALING	97	9.74e-01	1.95e-03	0.993000
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	9.74e-01	-1.83e-03	0.993000
REACTOME FOXO MEDIATED TRANSCRIPTION	65	9.75e-01	-2.29e-03	0.993000
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	9.75e-01	4.45e-03	0.993000
REACTOME SPRY REGULATION OF FGF SIGNALING	16	9.76e-01	-4.42e-03	0.993000
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	9.77e-01	1.05e-03	0.994000
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	9.78e-01	1.84e-03	0.994000
REACTOME TIE2 SIGNALING	18	9.79e-01	3.62e-03	0.994000
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	9.79e-01	3.38e-03	0.994000
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	9.80e-01	-2.98e-03	0.994000
REACTOME RHOBTB2 GTPASE CYCLE	22	9.82e-01	-2.80e-03	0.996000
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	9.83e-01	-4.39e-03	0.996000
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	9.84e-01	-4.80e-03	0.996000
REACTOME ACYL CHAIN REMODELLING OF PS	22	9.84e-01	-2.48e-03	0.996000
REACTOME PHASE 3 RAPID REPOLARISATION	8	9.86e-01	-3.60e-03	0.997000
REACTOME NEDDYLATION	235	9.86e-01	6.61e-04	0.997000
REACTOME RND2 GTPASE CYCLE	42	9.86e-01	1.52e-03	0.997000
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	9.87e-01	-9.23e-04	0.997000
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	9.87e-01	1.12e-03	0.997000
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	9.90e-01	-1.91e-03	0.997000
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	9.90e-01	-1.37e-03	0.997000
REACTOME SIGNALING BY ERYTHROPOIETIN	25	9.90e-01	1.43e-03	0.997000
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	9.91e-01	1.40e-03	0.997000
REACTOME SIGNALLING TO RAS	20	9.91e-01	-1.53e-03	0.997000
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	9.92e-01	-1.74e-03	0.997000
REACTOME G PROTEIN MEDIATED EVENTS	53	9.92e-01	-8.27e-04	0.997000
REACTOME ORGANIC ANION TRANSPORT	5	9.93e-01	2.20e-03	0.997000
REACTOME MISMATCH REPAIR	15	9.94e-01	-1.15e-03	0.997000
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	9.95e-01	5.54e-04	0.997000
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	9.95e-01	1.22e-03	0.997000
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	9.97e-01	-3.67e-04	0.999000
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	9.98e-01	2.99e-04	0.999000
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	9.99e-01	1.97e-04	1.000000
REACTOME NUCLEAR SIGNALING BY ERBB4	32	1.00e+00	3.98e-05	1.000000

---

Detailed Gene set reports

REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA

	1313
set	REACTOME_METABOLISM_OF_RNA
setSize	675
pANOVA	5.37e-07
s.dist	0.113
p.adjustANOVA	0.000882

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
RPL7A	11521
POP7	11490
GEMIN2	11457
EXOSC6	11380
RPS11	11368
SNRNP35	11224
GLE1	11223
NUP85	11204
SNRPD1	11129
RPL10L	10992
PWP2	10963
RPL17	10955
MPHOSPH10	10887
RPL23A	10886
PSMC3	10873
UTP3	10867
RPLP2	10866
RRP7A	10857
PRKCD	10816

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527.0
RPL7A	11521.0
POP7	11490.0
GEMIN2	11457.0
EXOSC6	11380.0
RPS11	11368.0
SNRNP35	11224.0
GLE1	11223.0
NUP85	11204.0
SNRPD1	11129.0
RPL10L	10992.0
PWP2	10963.0
RPL17	10955.0
MPHOSPH10	10887.0
RPL23A	10886.0
PSMC3	10873.0
UTP3	10867.0
RPLP2	10866.0
RRP7A	10857.0
PRKCD	10816.0
RPL12	10805.0
A1CF	10689.0
SET	10639.0
SNRNP40	10590.0
RBM28	10560.0
MAGOH	10465.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
PTBP1	10270.0
PSMB7	10268.0
EIF4G1	10221.0
ISG20L2	10194.0
THOC5	10190.0
PSMA1	10105.0
SRSF1	9991.0
RPL18	9942.0
RPL34	9922.0
EIF4A1	9908.0
UTP11	9870.0
APOBEC1	9859.0
PRCC	9839.0
RAE1	9805.0
PRORP	9792.0
SNRPD2	9791.0
IK	9767.0
WBP11	9745.0
RANBP2	9739.0
MTERF4	9729.0
ADAT1	9712.0
HNRNPA1	9695.0
EMG1	9630.0
MAPKAPK2	9627.0
WDR77	9583.0
SNRPG	9553.0
RPS27A	9528.0
TNFSF13	9518.0
PHAX	9514.0
ZMAT2	9512.0
TRMT112	9499.0
RBM25	9496.0
PNRC2	9475.0
POLR2D	9470.0
SMN1	9435.0
SMN2	9435.0
RPL22L1	9418.0
CLNS1A	9407.0
RBM8A	9403.0
ERI1	9345.0
AQR	9331.0
UTP4	9327.0
PCBP2	9322.0
RPL28	9256.0
DDX21	9252.0
SKIC8	9194.0
POLR2H	9192.0
RPL29	9176.0
PCBP1	9162.0
MTO1	9103.0
RPS24	9090.0
PSMB9	9005.0
RPLP0	8992.0
PSMD4	8872.0
DCP2	8863.0
DHX8	8856.0
TRMU	8820.0
XPO1	8796.0
RPL41	8792.0
RPL13	8763.0
WDR33	8746.0
GTF2H3	8733.0
PSMD11	8704.0
POM121C	8691.0
FAU	8682.0
RPS13	8647.0
ZC3H11A	8616.0
RPS14	8586.0
EIF4B	8573.0
POLR2C	8572.0
METTL3	8504.0
SMG6	8485.0
SNRPE	8476.0
NOP58	8449.0
PRPF6	8445.0
UTP15	8413.0
RPL13A	8411.5
KHSRP	8410.0
SNRPA	8307.0
SARNP	8290.0
TFB1M	8274.0
ELAC2	8265.0
TGS1	8261.0
SYF2	8258.0
NT5C3B	8240.0
TPRKB	8229.0
TRMT12	8186.0
RPS19	8143.0
PPP2R2A	8094.0
PRPF40A	8068.0
DCPS	8058.0
SF3A1	8040.0
THOC1	8018.0
METTL14	7997.0
NUP37	7970.0
RPL22	7968.0
PRPF3	7961.0
UPF3A	7901.0
TNKS1BP1	7860.0
POLR2G	7857.0
MFAP1	7837.0
NUDT21	7834.0
SNRPN	7794.0
RPS7	7735.0
NSUN4	7722.0
SEM1	7709.0
CPSF4	7692.0
FAM98B	7660.0
PSMD12	7629.0
RPS29	7569.0
UPF1	7531.0
NAT10	7479.0
NIP7	7441.0
RPS12	7345.0
DDX20	7269.0
SMG8	7230.0
SNRPC	7210.0
NOP56	7202.0
U2AF2	7099.0
HNRNPF	7061.0
FTSJ3	7033.0
BUD23	6982.0
CWC25	6882.0
NCBP2	6845.0
PSMC5	6830.0
PPP2CA	6783.0
PSMF1	6746.0
EXOSC4	6732.0
RPL24	6708.0
USP39	6673.0
PRMT5	6671.0
TCERG1	6657.0
KRR1	6624.0
FYTTD1	6610.0
QTRT2	6590.0
SAP18	6582.0
RPS3	6559.0
NUP42	6550.0
PSMB1	6496.0
YBX1	6453.0
PSMA4	6446.0
SNRPB	6432.0
HSPA1A	6417.0
U2SURP	6405.0
GTF2F2	6404.0
NUP58	6384.0
PSMA2	6356.0
RNMT	6346.0
UBC	6343.0
RPSA	6342.0
C2orf49	6332.0
DHX37	6310.0
PARN	6276.0
EIF4A2	6253.0
YWHAZ	6221.0
DHX16	6200.0
RPP40	6171.0
HNRNPA2B1	6153.0
NUP107	6064.0
WDR46	6042.0
NOP10	6036.0
EXOSC10	6028.0
RRP36	5995.0
RPS27	5993.0
RAN	5942.0
RPL37A	5921.0
HNRNPK	5904.0
RBM39	5866.0
TSEN2	5787.0
PPIL3	5773.0
GTF2H4	5769.0
PSMD3	5765.0
WBP4	5748.0
PSMA3	5711.0
PSMB8	5690.0
RBM5	5672.0
RPS6	5661.0
NSRP1	5654.0
NXT1	5628.0
DHX38	5605.0
GEMIN4	5570.0
SRSF2	5504.0
RTCB	5503.0
TXNL4A	5487.0
EIF4A3	5481.0
LSM10	5478.0
RNPC3	5462.0
TRMT5	5461.0
GEMIN5	5455.0
POLR2E	5439.0
PUF60	5410.0
HEATR1	5393.0
CACTIN	5338.0
UTP20	5330.0
PHF5A	5288.0
THUMPD1	5276.0
NCL	5265.0
BUD31	5260.0
CWC27	5256.0
NDC1	5235.0
SF3B3	5205.0
POM121	5192.0
RPS15A	5190.0
TUT7	5167.0
PRPF38A	5135.0
AAAS	5126.0
PRKCA	5109.0
ZFP36	5091.0
BOP1	5062.0
CSTF3	5045.0
ETF1	5022.0
NOL11	4980.0
SNRNP27	4962.0
TNPO1	4939.0
GEMIN7	4938.0
MAPK11	4874.0
DHX15	4872.0
PNO1	4799.0
TUT4	4765.0
DDX46	4759.0
SRSF3	4745.0
HNRNPU	4733.0
XRN2	4628.0
RPS5	4600.0
PDCD11	4588.0
PAIP1	4574.0
WDR36	4560.0
PCF11	4546.0
ANP32A	4525.0
GTPBP3	4521.0
HNRNPM	4503.0
RPL18A	4496.0
SMG7	4476.0
NUP88	4471.0
SRRT	4443.0
CNOT3	4422.0
HBS1L	4418.0
FCF1	4398.0
SF3B2	4382.0
C9orf78	4303.0
CTNNBL1	4255.0
SKIC3	4229.0
TPR	4207.0
PSME3	4177.0
SEH1L	4175.0
SNRNP48	4168.0
RPS3A	4153.0
MNAT1	4149.0
HSPA8	4148.0
PLRG1	4074.0
DCP1A	4051.0
RBM42	4030.0
DDX39A	3996.0
PSMB6	3982.0
EPRS1	3948.0
RPP14	3946.0
RTRAF	3940.0
TYW5	3933.0
SRRM2	3890.0
RIOK1	3887.0
SF3A2	3886.0
EXOSC3	3872.0
SLBP	3769.0
IMP4	3757.0
THOC6	3710.0
WDR4	3689.0
DHX9	3672.0
LSM3	3671.0
RPL38	3648.0
SRSF11	3524.0
LUC7L3	3471.0
DDX49	3438.0
SRSF10	3418.0
RPL15	3368.0
PUS7	3317.0
PUS3	3215.0
SF3B5	3198.0
QTRT1	3179.0
RBM7	3169.0
NCBP1	3154.0
HNRNPD	3115.0
TEX10	3106.0
SRSF9	3103.0
MRM3	3079.0
SF3B6	3078.0
TSEN54	3072.0
TRMT9B	3039.0
EFTUD2	3033.0
DDX41	3013.0
PSMD5	3011.0
CASC3	2989.0
MTREX	2962.0
CNOT2	2949.0
PSMB10	2924.0
PSMB4	2895.0
RPL3L	2883.0
NUP62	2832.0
ISY1	2811.0
SUPT5H	2754.0
PAN3	2744.0
SNRNP200	2741.0
PRPF8	2699.0
ACIN1	2667.0
CDC5L	2651.0
NUP205	2621.0
SENP3	2604.0
ZCRB1	2597.0
ZNF830	2583.0
DIMT1	2544.0
SNRNP70	2534.0
TYW3	2509.0
RPS9	2500.0
PSMA5	2491.0
PSME1	2473.0
SNRPD3	2471.0
TRNT1	2430.0
DIS3	2407.0
RBM17	2398.0
CNOT4	2393.0
ADAR	2380.0
SNUPN	2338.0
SKIC2	2309.0
RPS2	2297.0
HNRNPH1	2261.0
PSMD13	2253.0
PATL1	2240.0
TRIT1	2234.0
RPL26L1	2230.0
MRM2	2210.0
RPL31	2159.0
POLR2F	2100.0
GTF2H5	2062.0
RPL3	1947.0
SNU13	1938.0
EIF4E	1903.0
RPL36	1899.0
SNW1	1887.0
GAR1	1832.0
LENG1	1831.0
PUS1	1829.0
SART1	1827.0
PPIL1	1820.0
DDX42	1800.0
DDX1	1790.0
POLR2L	1774.0
RBM22	1700.0
NUP188	1699.0
FAM32A	1682.0
XRN1	1638.0
NSUN2	1555.0
FIP1L1	1509.0
CNOT9	1489.0
RRP1	1432.0
CPSF3	1326.0
PES1	1250.0
SLU7	1240.0
NUP214	1239.0
RPS27L	1225.0
WDR3	1202.0
HNRNPC	1191.0
UTP18	1175.0
RPS23	1164.0
RPL7	1159.0
TRDMT1	1135.0
RPL5	1132.0
TRMT13	1102.0
PPWD1	1073.0
PSMD6	1064.0
TRA2B	1063.0
DNAJC8	1056.0
GTF2F1	1054.0
NUP153	1016.0
RPL30	991.0
PSMD9	970.0
RPL10A	945.0
SF3B1	941.0
CCAR1	907.0
DDX5	877.0
PPP1R8	862.0
NUP43	847.0
U2AF1L4	769.0
RPL35A	733.0
UPF2	706.0
THOC7	674.0
PRPF31	659.0
NUP93	637.0
LSM5	628.0
CTU1	601.0
CPSF7	570.0
RPL26	511.0
NXF1	508.0
CDC40	490.0
THADA	486.0
HNRNPL	471.0
PPIL4	437.0
NUP210	420.0
EXOSC9	418.0
TRMT44	343.0
RPS10	340.0
SMU1	274.0
PSMD8	214.0
POLR2A	197.0
WDR75	167.0
NOC4L	162.0
LSM4	155.0
NUP54	148.0
PSMB5	136.0
RPL39L	118.0
YJU2	80.0
IGF2BP2	73.0
LSM7	39.0
EDC3	26.0
RNPS1	23.0
LSM2	-66.0
CSTF2T	-77.0
CDKAL1	-129.0
PABPN1	-180.0
RPL27A	-207.0
ADARB1	-226.0
UTP6	-238.0
RPL23	-246.0
TFIP11	-259.0
HNRNPR	-270.0
RPL35	-273.0
WDR18	-285.0
PSMA7	-337.0
PSME4	-360.0
PSMC1	-363.0
NSUN6	-367.0
SF1	-394.0
CPSF2	-433.0
WDR43	-525.0
CRNKL1	-554.0
LSM1	-654.0
PPIH	-760.0
CPSF1	-819.0
PAPOLA	-821.0
RPS20	-996.0
LSM8	-1007.0
CWC15	-1015.0
DDX39B	-1065.0
TSR1	-1117.0
OSGEP	-1124.0
PPIE	-1129.0
LSM11	-1169.0
CNOT1	-1186.0
CLP1	-1190.0
EBNA1BP2	-1222.0
UBB	-1252.0
CPSF6	-1255.0
RPL36AL	-1282.5
SRSF4	-1369.0
TRMT6	-1371.0
UTP25	-1481.0
PSMA6	-1500.0
NOL6	-1630.0
NUP133	-1680.0
RIOK2	-1734.0
CNOT10	-1736.0
RPP30	-1737.0
PABPC1	-1756.0
BUD13	-1774.0
MAPK14	-1781.0
GNL3	-1810.0
TRMT61A	-1812.0
BMS1	-1816.0
CSTF1	-1838.0
WDR70	-1844.0
RRP9	-1846.0
DDX52	-2027.0
PAN2	-2041.0
RPL9	-2057.0
GTF2H1	-2130.0
BYSL	-2133.0
APOBEC4	-2142.0
CDK7	-2166.0
UTP14C	-2171.0
POLR2B	-2172.0
ALYREF	-2211.0
RPL37	-2213.0
NOL9	-2216.0
PSMC6	-2235.0
SNRNP25	-2270.0
SNIP1	-2283.0
GSPT1	-2381.0
SRSF8	-2411.0
RPS26	-2447.0
CNOT6L	-2469.0
PSMB2	-2499.0
TSEN34	-2605.0
ZNF473	-2624.0
IGF2BP1	-2640.0
AKT1	-2646.0
RNGTT	-2718.0
RPS16	-2774.0
THG1L	-2779.0
ADAT3	-2780.0
SRSF7	-2785.0
PRKRIP1	-2799.0
PSMD14	-2853.0
NUP50	-2854.0
PSME2	-2879.0
TRMT61B	-2881.0
XAB2	-2915.0
APOBEC3H	-2930.0
SF3A3	-2955.0
PPIL2	-3001.0
ERCC2	-3009.0
NOP2	-3070.0
CCNH	-3092.0
IGF2BP3	-3096.0
RPP38	-3204.0
PSMC2	-3243.0
ZFP36L1	-3271.0
PSMD1	-3280.0
CHERP	-3284.0
MAGOHB	-3299.0
YWHAB	-3309.0
PRPF4	-3424.0
SMNDC1	-3443.0
POLR2K	-3444.0
PPP2R1A	-3530.0
PNN	-3727.0
DDX6	-3729.0
CSNK1D	-3900.0
ZBTB8OS	-3916.0
WDR12	-3964.0
CHTOP	-3968.0
EXOSC1	-3977.0
PELP1	-3985.0
RPL6	-3988.0
PRPF19	-4002.0
NUP98	-4024.0
TRMT1	-4026.0
ALKBH8	-4036.0
SNRPB2	-4106.0
PSMB3	-4168.0
TRMT10C	-4174.0
TP53RK	-4184.0
LTV1	-4230.0
CWC22	-4235.0
RPL11	-4362.0
GEMIN6	-4370.0
NHP2	-4376.0
RPS15	-4410.0
SNRPA1	-4512.0
WTAP	-4514.0
EXOSC2	-4552.0
DHX35	-4571.0
TRMT11	-4607.0
NOP14	-4686.0
RPL32	-4713.0
RPPH1	-4726.0
RPS25	-4757.0
PSMD7	-4907.0
POLDIP3	-5006.0
CNOT11	-5078.0
NUP155	-5088.0
RPLP1	-5104.0
DDX23	-5135.0
CNOT6	-5151.0
SMG9	-5226.0
UBL5	-5231.0
RPL21	-5327.0
CNOT8	-5380.0
MPHOSPH6	-5417.0
CCDC12	-5473.0
RPL19	-5474.0
PPIG	-5489.0
ERCC3	-5552.0
EXOSC8	-5555.0
PRPF18	-5652.0
PSMC4	-5662.0
SUGP1	-5701.0
LSM6	-5749.0
SRSF5	-5762.0
GPATCH1	-5907.0
NUP160	-5917.0
TRMT10A	-6011.0
POP5	-6072.0
SNRPF	-6098.0
PDCD7	-6119.0
EXOSC7	-6133.0
DDX47	-6151.0
SMG1	-6217.0
EDC4	-6228.0
NOB1	-6276.0
ZMAT5	-6279.0
NUP35	-6288.0
IMP3	-6361.0
POLR2I	-6444.0
RPP25	-6484.0
GCFC2	-6546.0
ELAVL1	-6584.0
RPL27	-6794.0
CSNK1E	-6804.0
SF3B4	-6837.0
DCP1B	-6858.0
DUS2	-6883.0
PSMA8	-6922.0
METTL1	-6984.0
APOBEC2	-7017.0
URM1	-7029.0
MRM1	-7052.0
PSMD2	-7108.0
RPP21	-7147.0
SRRM1	-7207.0
PSMB11	-7246.0
CWF19L2	-7282.0
C1D	-7407.0
RPS28	-7410.0
SRSF6	-7523.0
DCAF13	-7581.0
BCAS2	-7608.0
FBL	-7616.0
SYMPK	-7643.0
THOC3	-7651.0
HNRNPA3	-7684.0
TYW1	-7793.0
POP1	-7853.0
CNOT7	-7870.0
RPS21	-7890.0
ADAT2	-7909.0
POP4	-7977.0
CTU2	-8003.0
UBA52	-8028.0
TSEN15	-8219.0
RCL1	-8291.0
SMG5	-8310.0
XPOT	-8410.0
SDE2	-8464.0
RIOK3	-8485.0
TBL3	-8515.0
APOBEC3B	-8550.0
HSPB1	-8645.0
EXOSC5	-8682.0
SRSF12	-8751.0
NOL12	-8760.0
TSR3	-8968.0
LCMT2	-9294.0
FUS	-9390.0
APOBEC3C	-9498.0
APOBEC3A	-9692.0
POLR2J	-9903.0

---

REACTOME_TRANSLATION

REACTOME_TRANSLATION

	1152
set	REACTOME_TRANSLATION
setSize	278
pANOVA	2.07e-06
s.dist	0.165
p.adjustANOVA	0.0017

Top enriched genes

Top 20 genes

GeneID	Gene Rank
MRPL45	11715
RPL7A	11521
RPS11	11368
MRPL24	11123
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
MRPS7	10751
EIF3K	10623
AURKAIP1	10558
EIF2B5	10485
RPL4	10452
TSFM	10426
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
EIF4G1	10221

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
MRPL45	11715.0
RPL7A	11521.0
RPS11	11368.0
MRPL24	11123.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
MRPS7	10751.0
EIF3K	10623.0
AURKAIP1	10558.0
EIF2B5	10485.0
RPL4	10452.0
TSFM	10426.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
EIF4G1	10221.0
MRPL55	10219.0
EARS2	10208.0
SEC61A1	10158.0
RPN1	10042.0
MRPL11	9979.0
RPL18	9942.0
MRPL3	9940.0
RPL34	9922.0
EIF4A1	9908.0
PTCD3	9678.0
MRPL13	9585.0
RPS27A	9528.0
TRMT112	9499.0
SRP72	9471.0
RPL22L1	9418.0
MRPL18	9343.0
RPL28	9256.0
MRPL15	9230.0
RPL29	9176.0
TRAM1	9143.0
MRPS26	9104.0
RPS24	9090.0
MRPL9	9069.0
EEF1B2	9058.0
MRPL46	9015.0
RPLP0	8992.0
MRPL39	8991.0
SSR3	8943.0
RPL41	8792.0
RPL13	8763.0
NARS2	8683.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
EIF4B	8573.0
RPL13A	8411.5
MRPL49	8285.0
RPS19	8143.0
RPL22	7968.0
EEF1G	7866.0
MRPS14	7844.0
VARS2	7762.0
RPS7	7735.0
MRPS12	7696.0
LARS2	7622.0
RPS29	7569.0
EIF3D	7437.0
RPS12	7345.0
PPA1	7276.0
EIF4EBP1	7169.0
CARS1	7137.0
SSR2	6754.0
MRPL32	6744.0
RPL24	6708.0
MRRF	6704.0
RPS3	6559.0
MRPL52	6493.0
MRPS24	6378.0
RPSA	6342.0
SRPRB	6319.0
EIF4A2	6253.0
SEC61B	6184.0
MRPS27	6088.0
MRPL35	6066.0
RPS27	5993.0
RPL37A	5921.0
OXA1L	5872.0
MARS2	5852.0
SARS2	5793.0
EIF2S1	5780.0
AIMP1	5766.0
RPS6	5661.0
MRPL47	5645.0
EIF2B1	5492.0
EIF3E	5451.0
SPCS3	5335.0
MRPL21	5322.0
RPS15A	5190.0
SRP54	5150.0
MRPL34	5136.0
EIF2B3	5133.0
MRPS23	5051.0
ETF1	5022.0
MRPL36	5008.0
MRPS28	4979.0
DARS2	4934.0
MRPS18C	4830.0
EIF2B2	4823.0
EIF3H	4784.0
DARS1	4754.0
MRPS17	4727.0
LARS1	4609.0
RPS5	4600.0
SRP19	4594.0
AARS2	4552.0
RPL18A	4496.0
MRPL22	4480.0
CHCHD1	4470.0
AARS1	4326.0
TUFM	4292.0
MRPL27	4253.0
FARSA	4251.0
RPS3A	4153.0
MRPL53	4093.0
EEF1A1	4031.0
SEC11C	3989.0
VARS1	3984.0
EPRS1	3948.0
SEC11A	3832.0
MRPS25	3743.0
MRPS5	3715.0
ERAL1	3708.0
EIF3M	3664.0
RPL38	3648.0
MRPL43	3613.0
WARS2	3443.0
RPL15	3368.0
MRPL44	3362.0
IARS2	3285.0
RARS1	3150.0
MRPL57	3075.0
RPN2	3073.0
RPL3L	2883.0
EIF5B	2810.0
EIF3A	2776.0
MRPS10	2692.0
EEF2	2688.0
MRPS11	2608.0
RPS9	2500.0
EIF3L	2479.0
MRPL30	2369.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
EIF4E	1903.0
RPL36	1899.0
EEF1D	1807.0
YARS2	1793.0
MRPL10	1722.0
MRPS9	1687.0
MRPL14	1677.0
MRPL48	1636.0
SRP9	1573.0
MRPL2	1461.0
NARS1	1388.0
MARS1	1379.0
KARS1	1299.0
MRPL4	1285.0
TARS1	1251.0
RPS27L	1225.0
CARS2	1221.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
EIF4H	1066.0
GARS1	1065.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
MRPS34	720.0
EIF3B	636.0
AIMP2	550.0
RPL26	511.0
MRPS35	509.0
MRPS21	447.0
MRPS18B	401.0
RPS10	340.0
MRPL17	336.0
PARS2	191.0
MRPS15	137.0
RPL39L	118.0
GFM1	117.0
RPL27A	-207.0
GFM2	-244.0
RPL23	-246.0
RPL35	-273.0
SSR1	-324.0
SEC61G	-435.0
HARS1	-460.0
MRPS22	-613.0
RARS2	-672.0
SRPRA	-832.0
EIF2B4	-844.0
IARS1	-906.0
RPS20	-996.0
EIF3G	-1279.0
RPL36AL	-1282.5
MRPL1	-1378.0
MRPL37	-1380.0
N6AMT1	-1383.0
MRPL40	-1615.0
MRPL28	-1727.0
PABPC1	-1756.0
EIF3I	-1885.0
APEH	-1945.0
MRPL51	-2054.0
RPL9	-2057.0
RPL37	-2213.0
MTIF3	-2279.0
PPA2	-2307.0
MRPS30	-2336.0
GSPT1	-2381.0
WARS1	-2433.0
RPS26	-2447.0
MRPL33	-2592.0
MRPS2	-2633.0
RPS16	-2774.0
MRPL42	-2870.0
MTFMT	-2921.0
EEF1A2	-3013.0
MRPL54	-3027.0
MRPS16	-3062.0
FARS2	-3121.0
SRP68	-3464.0
DAP3	-3496.0
MRPL23	-3546.0
MRPS31	-3558.0
MRPS18A	-3812.0
FARSB	-3880.0
RPL6	-3988.0
MRPL19	-4019.0
EIF3F	-4023.0
MRPL58	-4077.0
RPL11	-4362.0
RPS15	-4410.0
EIF3J	-4610.0
MRPS33	-4669.0
RPL32	-4713.0
RPS25	-4757.0
MRPL41	-4812.0
MRPL16	-4886.0
YARS1	-4895.0
MRPL12	-4945.0
EEF1E1	-4963.0
HARS2	-5095.0
RPLP1	-5104.0
SRP14	-5210.0
EIF2S2	-5277.0
RPL21	-5327.0
RPL19	-5474.0
DDOST	-6114.0
SPCS2	-6174.0
MTRF1L	-6522.0
SEC61A2	-6699.0
GADD45GIP1	-6758.0
RPL27	-6794.0
MRPL38	-7090.0
SPCS1	-7099.0
RPS28	-7410.0
MRPL20	-7514.0
EIF5	-7878.0
RPS21	-7890.0
MRPS6	-8022.0
UBA52	-8028.0
TARS2	-8042.0
MTIF2	-8149.0
MRPL50	-8967.0

---

REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION

	228
set	REACTOME_INFLUENZA_INFECTION
setSize	149
pANOVA	6e-06
s.dist	0.215
p.adjustANOVA	0.00328

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
RPL7A	11521
RPS11	11368
NUP85	11204
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
RPL4	10452
RPL8	10360
CALR	10340
RPL14	10335
RPS8	10332
RPS18	10304
RPL18	9942
RPL34	9922
RAE1	9805
RANBP2	9739
RPS27A	9528

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527.0
RPL7A	11521.0
RPS11	11368.0
NUP85	11204.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
RPL4	10452.0
RPL8	10360.0
CALR	10340.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
RPL18	9942.0
RPL34	9922.0
RAE1	9805.0
RANBP2	9739.0
RPS27A	9528.0
POLR2D	9470.0
ISG15	9422.0
RPL22L1	9418.0
RPL28	9256.0
POLR2H	9192.0
RPL29	9176.0
EIF2AK2	9161.0
RPS24	9090.0
RPLP0	8992.0
XPO1	8796.0
RPL41	8792.0
RPL13	8763.0
POM121C	8691.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
POLR2C	8572.0
RPL13A	8411.5
GRSF1	8367.0
RPS19	8143.0
NUP37	7970.0
RPL22	7968.0
POLR2G	7857.0
RPS7	7735.0
CPSF4	7692.0
RPS29	7569.0
RPS12	7345.0
RPL24	6708.0
RPS3	6559.0
NUP42	6550.0
HSPA1A	6417.0
GTF2F2	6404.0
NUP58	6384.0
RPSA	6342.0
NUP107	6064.0
RPS27	5993.0
RAN	5942.0
RPL37A	5921.0
RPS6	5661.0
POLR2E	5439.0
NDC1	5235.0
POM121	5192.0
RPS15A	5190.0
AAAS	5126.0
RPS5	4600.0
RPL18A	4496.0
NUP88	4471.0
KPNA2	4429.0
IPO5	4337.0
TPR	4207.0
SEH1L	4175.0
RPS3A	4153.0
CANX	3978.0
KPNA1	3685.0
RPL38	3648.0
PARP1	3391.0
RPL15	3368.0
RPL3L	2883.0
NUP62	2832.0
NUP205	2621.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
KPNA5	2205.0
RPL31	2159.0
POLR2F	2100.0
RPL3	1947.0
RPL36	1899.0
POLR2L	1774.0
NUP188	1699.0
CLTA	1586.0
NUP214	1239.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
GTF2F1	1054.0
NUP153	1016.0
RPL30	991.0
RPL10A	945.0
NUP43	847.0
CLTC	758.0
RPL35A	733.0
NUP93	637.0
RPL26	511.0
HSP90AA1	431.0
NUP210	420.0
RPS10	340.0
POLR2A	197.0
NUP54	148.0
RPL39L	118.0
PABPN1	-180.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
KPNA4	-371.0
RPS20	-996.0
RPL36AL	-1282.5
NUP133	-1680.0
RPL9	-2057.0
POLR2B	-2172.0
RPL37	-2213.0
RPS26	-2447.0
RPS16	-2774.0
NUP50	-2854.0
DNAJC3	-3168.0
TGFB1	-3196.0
POLR2K	-3444.0
KPNA7	-3523.0
RPL6	-3988.0
NUP98	-4024.0
KPNA3	-4150.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
KPNB1	-4921.0
NUP155	-5088.0
RPLP1	-5104.0
RPL21	-5327.0
RPL19	-5474.0
NUP160	-5917.0
NUP35	-6288.0
POLR2I	-6444.0
RPL27	-6794.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0
POLR2J	-9903.0

---

REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION

	1053
set	REACTOME_NEUTROPHIL_DEGRANULATION
setSize	460
pANOVA	9.03e-06
s.dist	0.121
p.adjustANOVA	0.00371

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DEFA4	11956
LCN2	11945
S100A8	11918
RETN	11906
CEACAM6	11855
CD177	11827
ORM1	11771
CD68	11759
CTSG	11741
MPO	11718
AZU1	11706
MS4A3	11663
PRTN3	11607
PPBP	11551
S100A9	11541
S100A7	11481
S100A12	11426
HP	11316
RNASE3	11215
SLC11A1	11177

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DEFA4	11956
LCN2	11945
S100A8	11918
RETN	11906
CEACAM6	11855
CD177	11827
ORM1	11771
CD68	11759
CTSG	11741
MPO	11718
AZU1	11706
MS4A3	11663
PRTN3	11607
PPBP	11551
S100A9	11541
S100A7	11481
S100A12	11426
HP	11316
RNASE3	11215
SLC11A1	11177
SERPINA3	11165
CXCR1	11116
SLPI	11050
CEACAM8	10995
CD93	10993
OLFM4	10989
FABP5	10947
CDA	10917
PSMC3	10873
PYGB	10854
PRKCD	10816
APRT	10760
PTPRJ	10617
RAB27A	10495
CHIT1	10439
ITGAX	10401
CAT	10384
NIT2	10361
ADGRG3	10290
PSMB7	10268
FOLR3	10259
NRAS	10256
SIRPA	10253
MGST1	10180
NFAM1	10177
DEGS1	10164
FCN1	10124
TTR	10121
TCN1	10109
RHOF	10092
S100P	10087
FCGR3B	10068
ARG1	10011
GDI2	9898
DOK3	9895
CD33	9894
HVCN1	9874
LRG1	9765
MVP	9702
TMC6	9691
CTSA	9690
GNS	9665
HRNR	9660
ANPEP	9609
DSG1	9602
GSDMD	9527
CEACAM1	9498
PRG3	9350
SLC2A3	9346
AOC1	9335
CD14	9315
CEP290	9283
GRN	9234
GMFG	9152
SERPINB12	9068
TBC1D10C	9036
HSPA6	9034
TNFAIP6	9022
CHI3L1	9011
PLAC8	8984
CLEC4D	8963
TMEM30A	8924
SLCO4C1	8876
DSN1	8846
PSMD11	8704
SERPINA1	8698
CD36	8684
SLC2A5	8667
TARM1	8643
NPC2	8623
RAB7A	8612
PGLYRP1	8566
BST1	8552
NAPRT	8550
SIRPB1	8549
NFKB1	8542
VAT1	8492
ARPC5	8474
HLA-B	8428
PTGES2	8385
FPR2	8365
TUBB	8294
ITGAL	8289
OLR1	8238
ARHGAP9	8230
FCAR	8205
P2RX1	8200
SERPINB10	8146
ARL8A	8131
GM2A	8106
SIGLEC5	8103
ATP6V1D	8070
ITGAV	8060
PTPRC	8046
FAF2	7998
ATP6V0C	7898
SURF4	7868
PADI2	7833
ACTR1B	7788
PA2G4	7738
C3AR1	7631
PSMD12	7629
ELANE	7615
B2M	7530
DYNLL1	7506
JUP	7414
CTSH	7373
HPSE	7325
QSOX1	7305
CD53	7248
VAPA	7224
ADGRE3	7167
DYNC1H1	7135
KCNAB2	7127
LILRB3	7119
TSPAN14	7118
SCAMP1	7098
TUBB4B	7088
PRCP	7060
CSNK2B	6988
UNC13D	6941
STBD1	6883
AP1M1	6779
CLEC5A	6760
C1orf35	6756
CDK13	6683
CD44	6616
CALML5	6557
RNASE2	6545
ARHGAP45	6524
PSMB1	6496
APAF1	6444
HSPA1A	6417
CAB39	6414
PSMA2	6356
XRCC5	6340
PGM2	6279
LRRC7	6164
RAB37	6021
CYBA	5968
GSTP1	5796
PSMD3	5765
ACTR10	5676
ENPP4	5543
DYNLT1	5528
COPB1	5520
RHOG	5476
ADAM10	5459
DYNC1LI1	5408
MMP25	5232
NHLRC3	5212
FTL	5208
ORMDL3	5188
IMPDH1	5177
RAB5C	5083
GUSB	5066
DBNL	4983
XRCC6	4968
A1BG	4949
PTPN6	4836
CRISPLD2	4618
CD58	4586
RAP1A	4547
RAB18	4479
TIMP2	4445
GLB1	4403
SDCBP	4199
IRAG2	4181
HSPA8	4148
ARSA	4138
NEU1	4126
EEF1A1	4031
HMOX2	3975
RAB4B	3914
PFKL	3854
HBB	3808
ACLY	3791
GCA	3731
BIN2	3690
ADA2	3676
PTPRB	3640
TCIRG1	3612
CTSB	3569
PSAP	3439
ANO6	3403
CD59	3375
RAB44	3282
RAB31	3171
ATP11A	3153
ERP44	3116
ADGRE5	3095
MNDA	2953
RAP1B	2941
ATP11B	2927
CD55	2902
IDH1	2850
RNASET2	2838
DIAPH1	2829
SLC27A2	2825
AP2A2	2753
LPCAT1	2713
EEF2	2688
LAMTOR3	2625
PPIA	2624
FUCA2	2605
LTA4H	2522
PSMA5	2491
ROCK1	2365
PRDX6	2355
PSMD13	2253
CRACR2A	2225
CAP1	2222
DOCK2	2193
PYGL	2184
RAB24	2158
GALNS	2155
B4GALT1	2128
NCSTN	2123
PLD1	2076
TMEM179B	2066
NCKAP1L	2056
DSC1	2019
STING1	1894
SIGLEC14	1891
TICAM2	1828
ATG7	1821
VCL	1732
CYSTM1	1606
PECAM1	1596
RAB5B	1594
CPNE1	1584
SPTAN1	1571
TXNDC5	1550
GOLGA7	1547
AMPD3	1535
IGF2R	1501
CHRNB4	1483
DNAJC5	1418
RHOA	1411
CXCR2	1315
CST3	1291
LAMTOR2	1290
CD300A	1246
ALDH3B1	1172
PSMD6	1064
HEXB	1024
RAB10	829
MGAM	784
CCT8	756
CR1	735
CTSC	622
PLAU	614
PLAUR	579
GSN	553
CD47	492
RAB3A	434
HSP90AA1	431
RAB14	409
CAPN1	407
KCMF1	207
S100A11	161
ACAA1	160
PDAP1	125
TMBIM1	107
CEACAM3	100
IST1	37
CFD	11
TOLLIP	-10
SELL	-53
ACTR2	-261
TNFRSF1B	-481
HMGB1	-505
ARSB	-658
HK3	-686
PTPRN2	-753
NME2	-765
RAB6A	-806
MMP9	-839
QPCT	-873
ABCA13	-878
SLC44A2	-880
HSPA1B	-917
TMEM63A	-931
LTF	-1055
C6orf120	-1066
DPP7	-1093
PPIE	-1129
ATP8A1	-1167
ANXA2	-1204
YPEL5	-1205
TOM1	-1244
CAND1	-1248
SNAP25	-1294
GYG1	-1334
ATP6V0A1	-1427
FGR	-1486
BPI	-1549
PKM	-1597
SNAP29	-1654
CNN2	-1659
CANT1	-1675
ATP8B4	-1690
ILF2	-1723
MAPK14	-1781
AHSG	-1793
STOM	-1875
AGL	-1902
GAA	-1931
APEH	-1945
ITGB2	-1999
C3	-2020
HEBP2	-2046
LGALS3	-2056
FRK	-2070
GGH	-2110
GHDC	-2162
ALDOA	-2245
VPS35L	-2342
HLA-C	-2367
DNAJC13	-2558
MIF	-2566
LAMTOR1	-2576
SYNGR1	-2656
ITGAM	-2757
PSMD14	-2853
LILRA3	-2856
PGM1	-2871
AGPAT2	-2917
IMPDH2	-2929
PNP	-2960
DGAT1	-2983
VAMP8	-2991
PIGR	-2996
CLEC12A	-3002
PDXK	-3038
VCP	-3112
MAPK1	-3138
DNAJC3	-3168
PSMC2	-3243
PSMD1	-3280
AGA	-3285
TRAPPC1	-3308
CPPED1	-3350
CYB5R3	-3426
PTAFR	-3454
DSP	-3511
RAB3D	-3561
TRPM2	-3728
CKAP4	-3765
ALAD	-3835
CYFIP1	-4193
MLEC	-4253
PYCARD	-4258
CRISP3	-4271
GPR84	-4356
CXCL1	-4382
CREG1	-4432
PGAM1	-4486
ATAD3B	-4661
SIGLEC9	-4700
DERA	-4731
CMTM6	-4763
OSTF1	-4766
IQGAP2	-4832
PSMD7	-4907
KPNB1	-4921
ALOX5	-4986
FGL2	-5002
CD63	-5007
RAP2B	-5017
PSEN1	-5034
STK11IP	-5076
IQGAP1	-5089
ACP3	-5106
MAN2B1	-5111
PAFAH1B2	-5169
NFASC	-5178
SRP14	-5210
SERPINB1	-5221
LAMP1	-5289
CAMP	-5348
GLIPR1	-5376
ORM2	-5464
NBEAL2	-5468
SVIP	-5616
C5AR1	-5643
CSTB	-5754
COTL1	-5774
BRI3	-5835
ADAM8	-5908
SNAP23	-5935
UBR4	-6084
DDOST	-6114
STK10	-6226
ARMC8	-6234
FCER1G	-6239
RAC1	-6271
HGSNAT	-6299
FTH1	-6401
SERPINB6	-6402
HLA-A	-6482
HSP90AB1	-6618
ASAH1	-6646
FLG2	-6651
KRT1	-6702
GPI	-6710
MME	-6816
NDUFC2	-6833
OSCAR	-6937
SLC15A4	-7037
COMMD3	-7070
PSMD2	-7108
PKP1	-7158
PRSS3	-7235
SERPINB3	-7285
BST2	-7328
LAIR1	-7336
MANBA	-7398
PLEKHO2	-7476
CCT2	-7524
VNN1	-7543
COMMD9	-7656
LYZ	-8122
PTX3	-8150
CTSS	-8247
CTSD	-8287
CTSZ	-8560
TLR2	-8600
LILRB2	-8639
TYROBP	-8832
FCGR2A	-8842
CLEC4C	-8883
PRG2	-9040
ALDOC	-9111
CPNE3	-9161
MCEMP1	-9193
FUCA1	-9247
EPX	-9636
FPR1	-9651
MMP8	-9690

---

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD

	1443
set	REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize	107
pANOVA	1.4e-05
s.dist	0.243
p.adjustANOVA	0.0042

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
MAGOH	10465
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
EIF4G1	10221
RPL18	9942
RPL34	9922
RPS27A	9528
PNRC2	9475
RPL22L1	9418
RBM8A	9403

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
MAGOH	10465.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
EIF4G1	10221.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
PNRC2	9475.0
RPL22L1	9418.0
RBM8A	9403.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
SMG6	8485.0
RPL13A	8411.5
RPS19	8143.0
PPP2R2A	8094.0
RPL22	7968.0
UPF3A	7901.0
RPS7	7735.0
RPS29	7569.0
UPF1	7531.0
RPS12	7345.0
SMG8	7230.0
NCBP2	6845.0
PPP2CA	6783.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
RPS27	5993.0
RPL37A	5921.0
RPS6	5661.0
EIF4A3	5481.0
RPS15A	5190.0
ETF1	5022.0
RPS5	4600.0
RPL18A	4496.0
SMG7	4476.0
RPS3A	4153.0
DCP1A	4051.0
RPL38	3648.0
RPL15	3368.0
NCBP1	3154.0
CASC3	2989.0
RPL3L	2883.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
UPF2	706.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
RNPS1	23.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
RPS20	-996.0
RPL36AL	-1282.5
PABPC1	-1756.0
RPL9	-2057.0
RPL37	-2213.0
GSPT1	-2381.0
RPS26	-2447.0
RPS16	-2774.0
MAGOHB	-3299.0
PPP2R1A	-3530.0
RPL6	-3988.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
SMG9	-5226.0
RPL21	-5327.0
RPL19	-5474.0
SMG1	-6217.0
RPL27	-6794.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0
SMG5	-8310.0

---

REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME

	1595
set	REACTOME_ASPIRIN_ADME
setSize	42
pANOVA	1.54e-05
s.dist	0.385
p.adjustANOVA	0.0042

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UGT2B7	11819
ACSM2B	11245
ACSM4	10762
ACSM2A	10567
ABCC3	10313
CYP2C19	10225
UGT2A1	9703
UGT2B15	9450
UGT2B4	9241
CES2	9178
GLYATL1	8784
UGT1A5	8133
UGT2A3	7910
CYP2C8	7829
UGT1A1	7778
CES1	7727
UGT1A3	7679
GLYAT	7641
UGT2B11	7510
UGT1A4	7508

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UGT2B7	11819
ACSM2B	11245
ACSM4	10762
ACSM2A	10567
ABCC3	10313
CYP2C19	10225
UGT2A1	9703
UGT2B15	9450
UGT2B4	9241
CES2	9178
GLYATL1	8784
UGT1A5	8133
UGT2A3	7910
CYP2C8	7829
UGT1A1	7778
CES1	7727
UGT1A3	7679
GLYAT	7641
UGT2B11	7510
UGT1A4	7508
ABCC2	7076
UGT3A1	6728
UGT1A6	5809
UGT2B17	5633
CYP3A4	5241
BSG	4975
BCHE	4387
ALB	4349
CYP2D6	3850
UGT1A9	3580
UGT1A7	3316
GLYATL2	3074
UGT2A2	2278
GLYATL3	1870
SLCO2B1	1434
UGT3A2	1297
UGT1A8	1210
SLC16A1	-6
CYP2C9	-5808
SLC22A7	-6069
CYP2E1	-8019
ACSM5	-8537

---

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

	1149
set	REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize	110
pANOVA	1.9e-05
s.dist	0.236
p.adjustANOVA	0.00447

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
EIF3K	10623
EIF2B5	10485
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
EIF4G1	10221
RPL18	9942
RPL34	9922
EIF4A1	9908
RPS27A	9528
RPL22L1	9418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
EIF3K	10623.0
EIF2B5	10485.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
EIF4G1	10221.0
RPL18	9942.0
RPL34	9922.0
EIF4A1	9908.0
RPS27A	9528.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
EIF4B	8573.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
RPS7	7735.0
RPS29	7569.0
EIF3D	7437.0
RPS12	7345.0
EIF4EBP1	7169.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
EIF4A2	6253.0
RPS27	5993.0
RPL37A	5921.0
EIF2S1	5780.0
RPS6	5661.0
EIF2B1	5492.0
EIF3E	5451.0
RPS15A	5190.0
EIF2B3	5133.0
EIF2B2	4823.0
EIF3H	4784.0
RPS5	4600.0
RPL18A	4496.0
RPS3A	4153.0
EIF3M	3664.0
RPL38	3648.0
RPL15	3368.0
RPL3L	2883.0
EIF5B	2810.0
EIF3A	2776.0
RPS9	2500.0
EIF3L	2479.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
EIF4E	1903.0
RPL36	1899.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
EIF4H	1066.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
EIF3B	636.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
EIF2B4	-844.0
RPS20	-996.0
EIF3G	-1279.0
RPL36AL	-1282.5
PABPC1	-1756.0
EIF3I	-1885.0
RPL9	-2057.0
RPL37	-2213.0
RPS26	-2447.0
RPS16	-2774.0
RPL6	-3988.0
EIF3F	-4023.0
RPL11	-4362.0
RPS15	-4410.0
EIF3J	-4610.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
EIF2S2	-5277.0
RPL21	-5327.0
RPL19	-5474.0
RPL27	-6794.0
RPS28	-7410.0
EIF5	-7878.0
RPS21	-7890.0
UBA52	-8028.0

---

REACTOME_SNRNP_ASSEMBLY

REACTOME_SNRNP_ASSEMBLY

	322
set	REACTOME_SNRNP_ASSEMBLY
setSize	53
pANOVA	5.11e-05
s.dist	0.322
p.adjustANOVA	0.00964

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
GEMIN2	11457
NUP85	11204
SNRPD1	11129
RAE1	9805
SNRPD2	9791
RANBP2	9739
WDR77	9583
SNRPG	9553
PHAX	9514
SMN1	9435
SMN2	9435
CLNS1A	9407
POM121C	8691
SNRPE	8476
TGS1	8261
NUP37	7970
DDX20	7269
NCBP2	6845
PRMT5	6671

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527
GEMIN2	11457
NUP85	11204
SNRPD1	11129
RAE1	9805
SNRPD2	9791
RANBP2	9739
WDR77	9583
SNRPG	9553
PHAX	9514
SMN1	9435
SMN2	9435
CLNS1A	9407
POM121C	8691
SNRPE	8476
TGS1	8261
NUP37	7970
DDX20	7269
NCBP2	6845
PRMT5	6671
NUP42	6550
SNRPB	6432
NUP58	6384
NUP107	6064
GEMIN4	5570
GEMIN5	5455
NDC1	5235
POM121	5192
AAAS	5126
GEMIN7	4938
NUP88	4471
TPR	4207
SEH1L	4175
NCBP1	3154
NUP62	2832
NUP205	2621
SNRPD3	2471
SNUPN	2338
NUP188	1699
NUP214	1239
NUP153	1016
NUP43	847
NUP93	637
NUP210	420
NUP54	148
NUP133	-1680
NUP50	-2854
NUP98	-4024
GEMIN6	-4370
NUP155	-5088
NUP160	-5917
SNRPF	-6098
NUP35	-6288

---

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

	151
set	REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize	87
pANOVA	5.28e-05
s.dist	0.251
p.adjustANOVA	0.00964

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
RPL18	9942
RPL34	9922
RPS27A	9528
RPL22L1	9418
RPL28	9256
RPL29	9176
RPS24	9090
EEF1B2	9058

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
EEF1B2	9058.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
EEF1G	7866.0
RPS7	7735.0
RPS29	7569.0
RPS12	7345.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
RPS27	5993.0
RPL37A	5921.0
RPS6	5661.0
RPS15A	5190.0
RPS5	4600.0
RPL18A	4496.0
RPS3A	4153.0
EEF1A1	4031.0
RPL38	3648.0
RPL15	3368.0
RPL3L	2883.0
EEF2	2688.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
EEF1D	1807.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
RPS20	-996.0
RPL36AL	-1282.5
RPL9	-2057.0
RPL37	-2213.0
RPS26	-2447.0
RPS16	-2774.0
EEF1A2	-3013.0
RPL6	-3988.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
RPL21	-5327.0
RPL19	-5474.0
RPL27	-6794.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0

---

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

	271
set	REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize	105
pANOVA	7.42e-05
s.dist	0.224
p.adjustANOVA	0.012

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
SEC61A1	10158
RPN1	10042
RPL18	9942
RPL34	9922
RPS27A	9528
SRP72	9471
RPL22L1	9418
RPL28	9256

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
SEC61A1	10158.0
RPN1	10042.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
SRP72	9471.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
TRAM1	9143.0
RPS24	9090.0
RPLP0	8992.0
SSR3	8943.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
RPS7	7735.0
RPS29	7569.0
RPS12	7345.0
SSR2	6754.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
SRPRB	6319.0
SEC61B	6184.0
RPS27	5993.0
RPL37A	5921.0
RPS6	5661.0
SPCS3	5335.0
RPS15A	5190.0
SRP54	5150.0
RPS5	4600.0
SRP19	4594.0
RPL18A	4496.0
RPS3A	4153.0
SEC11C	3989.0
SEC11A	3832.0
RPL38	3648.0
RPL15	3368.0
RPN2	3073.0
RPL3L	2883.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
SRP9	1573.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
SSR1	-324.0
SEC61G	-435.0
SRPRA	-832.0
RPS20	-996.0
RPL36AL	-1282.5
RPL9	-2057.0
RPL37	-2213.0
RPS26	-2447.0
RPS16	-2774.0
SRP68	-3464.0
RPL6	-3988.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
SRP14	-5210.0
RPL21	-5327.0
RPL19	-5474.0
DDOST	-6114.0
SPCS2	-6174.0
SEC61A2	-6699.0
RPL27	-6794.0
SPCS1	-7099.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0

---

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY

	1601
set	REACTOME_SARS_COV_2_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	46
pANOVA	8.73e-05
s.dist	0.334
p.adjustANOVA	0.012

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GEMIN2	11457
RPS11	11368
SNRPD1	11129
RPS8	10332
RPS18	10304
SNRPD2	9791
SNRPG	9553
RPS27A	9528
SMN1	9435
SMN2	9435
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
SNRPE	8476
RPS19	8143
RPS7	7735
RPS29	7569
RPS12	7345
DDX20	7269

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GEMIN2	11457
RPS11	11368
SNRPD1	11129
RPS8	10332
RPS18	10304
SNRPD2	9791
SNRPG	9553
RPS27A	9528
SMN1	9435
SMN2	9435
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
SNRPE	8476
RPS19	8143
RPS7	7735
RPS29	7569
RPS12	7345
DDX20	7269
RPS3	6559
SNRPB	6432
RPSA	6342
RPS27	5993
RPS6	5661
GEMIN4	5570
GEMIN5	5455
RPS15A	5190
GEMIN7	4938
RPS5	4600
RPS3A	4153
RPS9	2500
SNRPD3	2471
RPS2	2297
RPS27L	1225
RPS23	1164
RPS10	340
RPS20	-996
RPS26	-2447
RPS16	-2774
GEMIN6	-4370
RPS15	-4410
RPS25	-4757
SNRPF	-6098
RPS28	-7410
RPS21	-7890

---

REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS

REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS

	420
set	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS
setSize	21
pANOVA	8.75e-05
s.dist	-0.494
p.adjustANOVA	0.012

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INS	-9227
NKX2-2	-8396
SLC2A2	-8166
IAPP	-8075
HNF4A	-7231
NEUROD1	-7093
PDX1	-7057
FOXA3	-6413
FOXA2	-5956
MAFA	-5736
AKT2	-5661
PAX6	-5051
PKLR	-3998
AKT3	-3722
NKX6-1	-3018
FOXO1	-2985
AKT1	-2646
GCK	-2165
RFX6	446
HNF1A	3219

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INS	-9227
NKX2-2	-8396
SLC2A2	-8166
IAPP	-8075
HNF4A	-7231
NEUROD1	-7093
PDX1	-7057
FOXA3	-6413
FOXA2	-5956
MAFA	-5736
AKT2	-5661
PAX6	-5051
PKLR	-3998
AKT3	-3722
NKX6-1	-3018
FOXO1	-2985
AKT1	-2646
GCK	-2165
RFX6	446
HNF1A	3219
HNF4G	5227

---

REACTOME_FATTY_ACIDS

REACTOME_FATTY_ACIDS

	430
set	REACTOME_FATTY_ACIDS
setSize	15
pANOVA	9.97e-05
s.dist	0.58
p.adjustANOVA	0.0126

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP2B6	10826
CYP4F8	10772
CYP4F2	10550
CYP4F12	10546
CYP4F11	9821
CYP2A13	8578
CYP4B1	7064
CYP2A7	7015
CYP2J2	6655
CYP4F3	5708
CYP2D6	3850
CYP4F22	1466
CYP2F1	-6075

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP2B6	10826
CYP4F8	10772
CYP4F2	10550
CYP4F12	10546
CYP4F11	9821
CYP2A13	8578
CYP4B1	7064
CYP2A7	7015
CYP2J2	6655
CYP4F3	5708
CYP2D6	3850
CYP4F22	1466
CYP2F1	-6075

---

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION

	1582
set	REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize	147
pANOVA	0.000135
s.dist	0.182
p.adjustANOVA	0.0158

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
ATP6V1E2	10737
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
RPL18	9942
RPL34	9922
ATP6V0D2	9656
RPS27A	9528
DDIT3	9504
RPL22L1	9418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527.0
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
ATP6V1E2	10737.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
RPL18	9942.0
RPL34	9922.0
ATP6V0D2	9656.0
RPS27A	9528.0
DDIT3	9504.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
SH3BP4	8973.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
ATF4	8560.0
RPL13A	8411.5
RPS19	8143.0
ATP6V1D	8070.0
RPL22	7968.0
WDR59	7932.0
ATP6V0C	7898.0
RPS7	7735.0
RPS29	7569.0
ATP6V1G1	7364.0
RPS12	7345.0
FNIP1	7174.0
SESN2	6964.0
RRAGC	6937.0
RPL24	6708.0
ATP6V1E1	6580.0
RPS3	6559.0
RPSA	6342.0
ATF2	6282.0
ATP6V1B1	6256.0
EIF2AK4	6067.0
RPS27	5993.0
RPL37A	5921.0
EIF2S1	5780.0
NPRL2	5741.0
RPS6	5661.0
RRAGD	5643.0
FLCN	5378.0
RPS15A	5190.0
ITFG2	5106.0
ATP6V1G2	4942.0
SZT2	4865.0
RPS5	4600.0
RPL18A	4496.0
SEH1L	4175.0
RPS3A	4153.0
TRIB3	4144.0
RPL38	3648.0
RRAGA	3619.0
TCIRG1	3612.0
SLC38A9	3510.0
RPL15	3368.0
ATF3	3311.0
ATP6V1A	3298.0
RPTOR	3292.0
ATP6V1H	3135.0
BMT2	3061.0
RHEB	2938.0
RPL3L	2883.0
LAMTOR5	2809.0
LAMTOR3	2625.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
MTOR	2131.0
KICS2	1989.0
RPL3	1947.0
RPL36	1899.0
MLST8	1708.0
NPRL3	1429.0
ATP6V1F	1344.0
LAMTOR2	1290.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
ATP6V0E1	1095.0
RPL30	991.0
ATP6V1C1	946.0
RPL10A	945.0
ATP6V0B	819.0
RPL35A	733.0
RPL26	511.0
LAMTOR4	474.0
RPS10	340.0
DEPDC5	303.0
RPL39L	118.0
GCN1	24.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
RPS20	-996.0
RPL36AL	-1282.5
SESN1	-1918.0
KPTN	-1977.0
RPL9	-2057.0
RPL37	-2213.0
ATP6V1B2	-2437.0
RPS26	-2447.0
LAMTOR1	-2576.0
RPS16	-2774.0
ATP6V1G3	-3437.0
RPL6	-3988.0
ATP6V1C2	-4210.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
EIF2S2	-5277.0
RPL21	-5327.0
ATP6V0D1	-5365.0
RPL19	-5474.0
ASNS	-5904.0
FNIP2	-6204.0
CEBPB	-6379.0
CASTOR1	-6443.0
RPL27	-6794.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0
CEBPG	-8037.0
IMPACT	-8449.0
WDR24	-8893.0
MIOS	-8905.0
ATP6V0E2	-9852.0

---

REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

	293
set	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT
setSize	41
pANOVA	0.000214
s.dist	-0.334
p.adjustANOVA	0.0234

Top enriched genes

Top 20 genes

GeneID	Gene Rank
INS	-9227
NKX2-2	-8396
HNF1B	-8230
SLC2A2	-8166
IAPP	-8075
PAX4	-7930
HNF4A	-7231
NEUROD1	-7093
PDX1	-7057
FOXA3	-6413
FOXA2	-5956
PTF1A	-5827
MAFA	-5736
AKT2	-5661
PAX6	-5051
RBPJ	-5010
INSM1	-4426
ONECUT1	-4105
FGF10	-4015
PKLR	-3998

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
INS	-9227
NKX2-2	-8396
HNF1B	-8230
SLC2A2	-8166
IAPP	-8075
PAX4	-7930
HNF4A	-7231
NEUROD1	-7093
PDX1	-7057
FOXA3	-6413
FOXA2	-5956
PTF1A	-5827
MAFA	-5736
AKT2	-5661
PAX6	-5051
RBPJ	-5010
INSM1	-4426
ONECUT1	-4105
FGF10	-4015
PKLR	-3998
AKT3	-3722
KAT2B	-3471
NKX6-1	-3018
FOXO1	-2985
AKT1	-2646
NR5A2	-2608
ONECUT3	-2369
GCK	-2165
MAML3	-1099
NEUROG3	-287
RFX6	446
HES1	917
MAML1	1760
SNW1	1887
HNF1A	3219
NOTCH1	3452
EP300	4662
CREBBP	4677
MAML2	4859
HNF4G	5227
KAT2A	10312

---

REACTOME_NEURONAL_SYSTEM

REACTOME_NEURONAL_SYSTEM

	34
set	REACTOME_NEURONAL_SYSTEM
setSize	388
pANOVA	0.000347
s.dist	-0.106
p.adjustANOVA	0.0344

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LRRTM1	-9602
GNG11	-9535
KCNK7	-9376
KCNJ8	-9359
TUBB2B	-9250
SLITRK5	-9137
KCNK6	-9084
CHRNA5	-9066
KCNK1	-9004
SLITRK3	-8962
KCNN4	-8857
HRAS	-8845
GABRG2	-8844
GNG3	-8811
KCNA4	-8772
TUBA8	-8659
UNC13B	-8621
KCNJ3	-8570
TUBB4A	-8558
APBA1	-8510

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LRRTM1	-9602
GNG11	-9535
KCNK7	-9376
KCNJ8	-9359
TUBB2B	-9250
SLITRK5	-9137
KCNK6	-9084
CHRNA5	-9066
KCNK1	-9004
SLITRK3	-8962
KCNN4	-8857
HRAS	-8845
GABRG2	-8844
GNG3	-8811
KCNA4	-8772
TUBA8	-8659
UNC13B	-8621
KCNJ3	-8570
TUBB4A	-8558
APBA1	-8510
CACNG8	-8494
SLC32A1	-8484
KCNN1	-8398
GRIN1	-8278
AKAP5	-8277
CHRNA4	-8204
KCNA3	-8188
PPM1E	-8103
NEFL	-7986
SLC18A3	-7955
KCNJ14	-7832
SLC5A7	-7824
ADCY7	-7812
CACNG3	-7798
GABRR1	-7725
KCNG1	-7703
GABRA2	-7660
KCNN2	-7629
TUBA1C	-7521
TUBA3C	-7461
GJA10	-7442
KCNJ2	-7357
GRIN2D	-7294
TUBB6	-7272
LRRTM2	-7061
KCNH6	-7020
CACNA1B	-6972
KCNK10	-6939
SLC6A12	-6857
CHRND	-6855
KCNS1	-6743
TUBA3D	-6718
KCNJ10	-6687
PDPK1	-6640
SLC6A4	-6535
PRKAR2B	-6534
GNG2	-6513
ADCY8	-6507
GNAI3	-6470
KCNS3	-6452
CACNG4	-6374
SLC17A7	-6353
GNG8	-6304
RAC1	-6271
KCND2	-6194
SLC18A2	-6077
EPB41L3	-6038
LRRC4B	-5966
GABRB1	-5944
GLRB	-5934
LRTOMT	-5923
MAPT	-5909
GNAI1	-5875
KCNA1	-5834
PRKAA2	-5787
GRIK4	-5622
ACHE	-5580
CHAT	-5523
LIN7B	-5430
AP2M1	-5421
DLGAP3	-5402
CACNA2D2	-5330
APBA2	-5243
KCNV1	-5237
KCNA5	-5236
GRIN3B	-5079
HTR3B	-4991
LRFN3	-4965
PRKACA	-4802
TUBA4B	-4772
ADCY4	-4707
SLC6A13	-4687
GNG4	-4676
PRKCG	-4651
KCNQ2	-4629
KCNJ6	-4563
ACTN2	-4500
NAAA	-4494
SLC22A2	-4488
CAMK2B	-4476
SYT10	-4445
GRIN2C	-4406
KCNC1	-4353
GJD2	-4338
NCALD	-4317
PRKAG3	-4310
CALM1	-4297
EPB41L5	-4269
KCNH2	-4266
DLGAP4	-4255
SLC6A3	-4240
ARL6IP5	-4117
NTRK3	-4111
SLC6A1	-4076
PLCB2	-4046
CHRNE	-3910
HCN3	-3892
KCNS2	-3882
SLC1A1	-3872
KRAS	-3860
MDM2	-3839
GLRA1	-3773
GRIK3	-3674
GABRA5	-3621
CACNA1E	-3611
SYT2	-3565
KCNG3	-3553
KCNA7	-3469
KCNK4	-3465
GRIN2A	-3418
GAD1	-3407
GNB4	-3317
GJC1	-3246
AP2B1	-3170
GNAI2	-3163
MAPK1	-3138
KCNG4	-3089
LIN7A	-2980
KCNMA1	-2939
CACNB4	-2896
CHRNB3	-2865
CHRNB2	-2760
KCNK9	-2751
KCNV2	-2736
KCNMB1	-2733
KCNK17	-2724
STX1A	-2588
DLG4	-2534
IL1RAP	-2489
KIF17	-2484
NPTN	-2464
TUBB2A	-2445
PRKAG1	-2442
CHRNA3	-2436
MYO6	-2416
CHRNA2	-2400
TUBA4A	-2383
CREB1	-2363
SHANK1	-2258
TUBB3	-2163
GABRR2	-2104
GNGT2	-2033
GRIA2	-1951
CPLX1	-1949
KCNAB3	-1852
GNG5	-1791
SLC1A3	-1739
CAMKK1	-1730
NRXN3	-1688
SYT9	-1656
KCNJ12	-1652
KCNAB1	-1582
ADCY1	-1581
BEGAIN	-1567
RASGRF1	-1555
PPFIA2	-1450
PRKAR2A	-1406
SNAP25	-1294
KCNN3	-1236
NRXN2	-1183
GNAL	-1025
KCNB2	-918
PTPRS	-859
GRIA4	-850
GAD2	-826
GABRA1	-802
NRXN1	-703
GABRG3	-688
HCN2	-650
GRIP1	-616
CACNB3	-604
KCNF1	-588
APBA3	-480
GABRB2	-329
KCNQ3	-290
RPS6KA2	-209
CACNB2	-205
KCNG2	-197
AP2A1	-132
KCND3	-127
CACNG2	-111
PTPRD	-72
KCNB1	20
KCNH1	42
KCNH4	46
KCNMB2	144
CAMK1	146
KCNJ15	216
RIMS1	308
RPS6KA1	327
SLC1A6	338
RAB3A	434
KCNH5	595
SLC38A2	639
KCNJ4	654
NBEA	699
LRFN2	823
ABCC8	855
PPFIA3	884
SYN2	890
HCN4	929
PPM1F	948
KCNQ4	960
ADCY5	1029
KCNK16	1044
GNGT1	1092
KCNJ1	1130
SYT7	1147
PPFIBP2	1205
GABRA4	1385
NRGN	1391
DNAJC5	1418
NLGN1	1440
CHRNB4	1483
GLS	1511
LRRTM3	1562
HTR3A	1618
KCNQ1	1631
ADCY3	1639
FLOT2	1678
GRIK5	1818
KCNC3	1982
KCNK3	2012
ADCY2	2059
EPB41L1	2115
PPFIA1	2165
AP2S1	2236
PPFIBP1	2272
KCNK2	2311
KCNQ5	2346
SLC22A1	2405
PRKCB	2423
NRG1	2502
GRM1	2517
ARHGEF7	2582
KCNJ9	2602
PLCB3	2614
MAPK3	2655
ERBB4	2674
PDLIM5	2703
AP2A2	2753
CAMK2A	2854
TUBAL3	2860
DLGAP1	2904
GRIK1	2955
ADCY9	2982
GNB5	3005
SLC1A2	3019
SHANK2	3040
GRIN3A	3049
PRKAR1A	3147
RASGRF2	3194
PPFIA4	3206
KCNK13	3207
KCNA6	3304
GRIN2B	3346
GNG12	3495
GNB1	3572
COMT	3600
GIT1	3621
HTR3D	3644
SLC1A7	3678
CACNA1A	3688
HTR3E	3704
GABBR1	3717
PRKACB	3804
CAMK4	3824
DLG1	3825
ADCY6	3899
ABCC9	3918
NLGN2	3951
GRIP2	4022
PRKAR1B	4059
KCNK18	4078
PRKAB2	4095
HSPA8	4148
KCNH3	4196
VAMP2	4225
LRFN1	4262
GNG13	4294
KCNJ5	4346
BCHE	4387
KPNA2	4429
GABRB3	4542
SYT1	4554
KCNA10	4563
GNAT3	4626
GRIK2	4627
HOMER1	4638
GNB2	4816
LRFN4	4908
SLC6A11	4923
SHARPIN	4967
DBNL	4983
EPB41L2	5061
KCNH7	5072
PRKCA	5109
SYT12	5198
LRRTM4	5206
CAMK2D	5270
DLG2	5367
PTPRF	5551
HOMER3	5580
TUBB8	5589
PLCB1	5601
GNG7	5612
CAMKK2	5626
STXBP1	5733
EPB41	5820
KCNC4	5884
GABBR2	5898
LRRC7	6164
RTN3	6238
KCNJ11	6240
GRM5	6438
HTR3C	6451
NSF	6538
SIPA1L1	6844
TUBA1A	7010
TUBB4B	7088
KCNAB2	7127
PRKAG2	7192
GLRA3	7247
DLGAP2	7401
PRKACG	7521
KCNJ16	7664
KCNH8	7693
GNG10	7743
CHRNA1	7767
PRKAB1	7861
ALDH2	7973
ALDH5A1	8087
CHRNA7	8089
PRKAA1	8210
TSPOAP1	8398
CACNA2D3	8437
SYN3	8554
GLS2	8627
PANX2	8652
HCN1	8669
GLUL	8790
PICK1	8798
KCNC2	8799
SRC	8847
CHRNA6	8859
GABRR3	8965
LIN7C	9010
SLC38A1	9095
KCNMB4	9402
GABRA6	9433
PANX1	9533
HOMER2	9559
SLITRK1	9579
CAMK2G	9674
KCNMB3	9715
KCNA2	9719
GRIA1	9726
ABAT	9858
FLOT1	9862
CHRNA9	9864
TUBA1B	9875
CHRNG	10038
CACNB1	10159
NRAS	10256
TUBA3E	10342
TUBB1	10414
SLITRK6	10904
GNB3	11194

---

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

	1486
set	REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize	94
pANOVA	0.000356
s.dist	0.213
p.adjustANOVA	0.0344

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
RPLP2	10866
RPL12	10805
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
RPL18	9942
RPL34	9922
RPS27A	9528
DDIT3	9504
RPL22L1	9418
RPL28	9256
RPL29	9176
RPS24	9090

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
RPLP2	10866.0
RPL12	10805.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
DDIT3	9504.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
ATF4	8560.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
RPS7	7735.0
RPS29	7569.0
RPS12	7345.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
ATF2	6282.0
EIF2AK4	6067.0
RPS27	5993.0
RPL37A	5921.0
EIF2S1	5780.0
RPS6	5661.0
RPS15A	5190.0
RPS5	4600.0
RPL18A	4496.0
RPS3A	4153.0
TRIB3	4144.0
RPL38	3648.0
RPL15	3368.0
ATF3	3311.0
RPL3L	2883.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
GCN1	24.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
RPS20	-996.0
RPL36AL	-1282.5
RPL9	-2057.0
RPL37	-2213.0
RPS26	-2447.0
RPS16	-2774.0
RPL6	-3988.0
RPL11	-4362.0
RPS15	-4410.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
EIF2S2	-5277.0
RPL21	-5327.0
RPL19	-5474.0
ASNS	-5904.0
CEBPB	-6379.0
RPL27	-6794.0
RPS28	-7410.0
RPS21	-7890.0
UBA52	-8028.0
CEBPG	-8037.0
IMPACT	-8449.0

---

REACTOME_EICOSANOIDS

REACTOME_EICOSANOIDS

	434
set	REACTOME_EICOSANOIDS
setSize	12
pANOVA	0.000427
s.dist	0.587
p.adjustANOVA	0.0389

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP4F8	10772
CYP4F2	10550
CYP4F12	10546
CYP4F11	9821
TBXAS1	7422
CYP4B1	7064
CYP8B1	6122
CYP4F3	5708
CYP4F22	1466
PTGIS	-3808

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP4F8	10772
CYP4F2	10550
CYP4F12	10546
CYP4F11	9821
TBXAS1	7422
CYP4B1	7064
CYP8B1	6122
CYP4F3	5708
CYP4F22	1466
PTGIS	-3808

---

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

	1146
set	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA
setSize	263
pANOVA	0.000457
s.dist	0.126
p.adjustANOVA	0.0395

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
SNRNP35	11224
GLE1	11223
NUP85	11204
SNRPD1	11129
SNRNP40	10590
MAGOH	10465
PTBP1	10270
THOC5	10190
SRSF1	9991
PRCC	9839
RAE1	9805
SNRPD2	9791
IK	9767
WBP11	9745
RANBP2	9739
HNRNPA1	9695
SNRPG	9553
ZMAT2	9512
RBM25	9496

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527
SNRNP35	11224
GLE1	11223
NUP85	11204
SNRPD1	11129
SNRNP40	10590
MAGOH	10465
PTBP1	10270
THOC5	10190
SRSF1	9991
PRCC	9839
RAE1	9805
SNRPD2	9791
IK	9767
WBP11	9745
RANBP2	9739
HNRNPA1	9695
SNRPG	9553
ZMAT2	9512
RBM25	9496
POLR2D	9470
RBM8A	9403
AQR	9331
PCBP2	9322
POLR2H	9192
PCBP1	9162
DHX8	8856
WDR33	8746
POM121C	8691
ZC3H11A	8616
POLR2C	8572
METTL3	8504
SNRPE	8476
PRPF6	8445
SNRPA	8307
SARNP	8290
SYF2	8258
PRPF40A	8068
SF3A1	8040
THOC1	8018
METTL14	7997
NUP37	7970
PRPF3	7961
POLR2G	7857
MFAP1	7837
NUDT21	7834
SNRPN	7794
CPSF4	7692
SNRPC	7210
U2AF2	7099
HNRNPF	7061
CWC25	6882
NCBP2	6845
USP39	6673
TCERG1	6657
FYTTD1	6610
SAP18	6582
NUP42	6550
YBX1	6453
SNRPB	6432
U2SURP	6405
GTF2F2	6404
NUP58	6384
DHX16	6200
HNRNPA2B1	6153
NUP107	6064
HNRNPK	5904
RBM39	5866
PPIL3	5773
WBP4	5748
RBM5	5672
NSRP1	5654
NXT1	5628
DHX38	5605
SRSF2	5504
TXNL4A	5487
EIF4A3	5481
RNPC3	5462
POLR2E	5439
PUF60	5410
CACTIN	5338
PHF5A	5288
BUD31	5260
CWC27	5256
NDC1	5235
SF3B3	5205
POM121	5192
PRPF38A	5135
AAAS	5126
CSTF3	5045
SNRNP27	4962
DHX15	4872
DDX46	4759
SRSF3	4745
HNRNPU	4733
PCF11	4546
HNRNPM	4503
NUP88	4471
SRRT	4443
SF3B2	4382
C9orf78	4303
CTNNBL1	4255
TPR	4207
SEH1L	4175
SNRNP48	4168
HSPA8	4148
PLRG1	4074
RBM42	4030
DDX39A	3996
SRRM2	3890
SF3A2	3886
SLBP	3769
THOC6	3710
DHX9	3672
LSM3	3671
SRSF11	3524
LUC7L3	3471
SRSF10	3418
SF3B5	3198
RBM7	3169
NCBP1	3154
HNRNPD	3115
SRSF9	3103
SF3B6	3078
EFTUD2	3033
DDX41	3013
CASC3	2989
MTREX	2962
NUP62	2832
ISY1	2811
SNRNP200	2741
PRPF8	2699
ACIN1	2667
CDC5L	2651
NUP205	2621
ZCRB1	2597
ZNF830	2583
SNRNP70	2534
SNRPD3	2471
RBM17	2398
HNRNPH1	2261
POLR2F	2100
SNU13	1938
EIF4E	1903
SNW1	1887
LENG1	1831
SART1	1827
PPIL1	1820
DDX42	1800
POLR2L	1774
RBM22	1700
NUP188	1699
FAM32A	1682
FIP1L1	1509
CPSF3	1326
SLU7	1240
NUP214	1239
HNRNPC	1191
PPWD1	1073
TRA2B	1063
DNAJC8	1056
GTF2F1	1054
NUP153	1016
SF3B1	941
CCAR1	907
DDX5	877
PPP1R8	862
NUP43	847
U2AF1L4	769
THOC7	674
PRPF31	659
NUP93	637
LSM5	628
CPSF7	570
NXF1	508
CDC40	490
HNRNPL	471
PPIL4	437
NUP210	420
SMU1	274
POLR2A	197
LSM4	155
NUP54	148
YJU2	80
LSM7	39
RNPS1	23
LSM2	-66
CSTF2T	-77
PABPN1	-180
TFIP11	-259
HNRNPR	-270
SF1	-394
CPSF2	-433
CRNKL1	-554
PPIH	-760
CPSF1	-819
PAPOLA	-821
LSM8	-1007
CWC15	-1015
DDX39B	-1065
PPIE	-1129
CLP1	-1190
CPSF6	-1255
SRSF4	-1369
NUP133	-1680
BUD13	-1774
CSTF1	-1838
WDR70	-1844
POLR2B	-2172
ALYREF	-2211
SNRNP25	-2270
SNIP1	-2283
SRSF8	-2411
SRSF7	-2785
PRKRIP1	-2799
NUP50	-2854
XAB2	-2915
SF3A3	-2955
PPIL2	-3001
CHERP	-3284
MAGOHB	-3299
PRPF4	-3424
SMNDC1	-3443
POLR2K	-3444
PNN	-3727
CHTOP	-3968
PRPF19	-4002
NUP98	-4024
SNRPB2	-4106
CWC22	-4235
SNRPA1	-4512
WTAP	-4514
DHX35	-4571
POLDIP3	-5006
NUP155	-5088
DDX23	-5135
UBL5	-5231
CCDC12	-5473
PPIG	-5489
PRPF18	-5652
SUGP1	-5701
LSM6	-5749
SRSF5	-5762
GPATCH1	-5907
NUP160	-5917
SNRPF	-6098
PDCD7	-6119
ZMAT5	-6279
NUP35	-6288
POLR2I	-6444
GCFC2	-6546
SF3B4	-6837
SRRM1	-7207
CWF19L2	-7282
SRSF6	-7523
BCAS2	-7608
SYMPK	-7643
THOC3	-7651
HNRNPA3	-7684
SDE2	-8464
SRSF12	-8751
FUS	-9390
POLR2J	-9903

---

REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM

	227
set	REACTOME_INNATE_IMMUNE_SYSTEM
setSize	1002
pANOVA	0.000561
s.dist	0.0644
p.adjustANOVA	0.0461

Top enriched genes

Top 20 genes

GeneID	Gene Rank
DEFA4	11956
LCN2	11945
S100A8	11918
RETN	11906
CD3G	11876
CEACAM6	11855
IFNA21	11843
CD177	11827
ORM1	11771
CD209	11767
CD68	11759
CTSG	11741
MPO	11718
AZU1	11706
DCD	11694
MS4A3	11663
RNASE8	11620
PRTN3	11607
MUC5AC	11572
IFNA16	11557

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
DEFA4	11956.0
LCN2	11945.0
S100A8	11918.0
RETN	11906.0
CD3G	11876.0
CEACAM6	11855.0
IFNA21	11843.0
CD177	11827.0
ORM1	11771.0
CD209	11767.0
CD68	11759.0
CTSG	11741.0
MPO	11718.0
AZU1	11706.0
DCD	11694.0
MS4A3	11663.0
RNASE8	11620.0
PRTN3	11607.0
MUC5AC	11572.0
IFNA16	11557.0
CD300E	11554.0
PPBP	11551.0
S100A9	11541.0
MBL2	11526.0
S100A7	11481.0
DEFB119	11453.0
GRAP2	11436.0
S100A12	11426.0
LCK	11410.0
DEFB113	11366.0
MEFV	11352.0
HP	11316.0
RNASE3	11215.0
RNASE6	11200.0
TKFC	11185.0
SLC11A1	11177.0
SERPINA3	11165.0
CFHR2	11138.0
CXCR1	11116.0
SLPI	11050.0
CEACAM8	10995.0
CD93	10993.0
OLFM4	10989.0
DEFB124	10975.0
FABP5	10947.0
CDA	10917.0
PSMC3	10873.0
PYGB	10854.0
PRKCD	10816.0
C5AR2	10793.0
S100B	10786.0
APRT	10760.0
ATP6V1E2	10737.0
RASGRP2	10671.0
PTPRJ	10617.0
AIM2	10563.0
RAB27A	10495.0
ICAM3	10478.0
IFNB1	10449.0
CLEC6A	10442.0
CHIT1	10439.0
CPN2	10417.0
COLEC10	10408.0
ITGAX	10401.0
CAT	10384.0
SERPING1	10375.0
NIT2	10361.0
TLR10	10316.0
TOMM70	10308.0
SHC1	10295.0
ADGRG3	10290.0
PLA2G2A	10273.0
PSMB7	10268.0
FOLR3	10259.0
NRAS	10256.0
SIRPA	10253.0
MGST1	10180.0
NFAM1	10177.0
DEGS1	10164.0
IFIH1	10139.0
UBE2N	10132.0
FCN1	10124.0
TTR	10121.0
TCN1	10109.0
PSMA1	10105.0
RHOF	10092.0
S100P	10087.0
FCGR3B	10068.0
C1QC	10031.0
ARG1	10011.0
PSTPIP1	10008.0
TLR9	10007.0
PI3	9987.0
DEFB114	9956.0
NLRC5	9952.0
GDI2	9898.0
DOK3	9895.0
CD33	9894.0
HLA-E	9885.0
HVCN1	9874.0
RAC2	9811.0
HTN3	9794.0
LRG1	9765.0
NCF4	9704.0
MVP	9702.0
TMC6	9691.0
CTSA	9690.0
GNS	9665.0
HRNR	9660.0
ATP6V0D2	9656.0
MAPKAPK2	9627.0
ANPEP	9609.0
DSG1	9602.0
TBK1	9570.0
DEFB132	9561.0
PANX1	9533.0
CCL22	9532.0
RPS27A	9528.0
GSDMD	9527.0
CEACAM1	9498.0
ISG15	9422.0
PGLYRP3	9408.0
PRG3	9350.0
SLC2A3	9346.0
AOC1	9335.0
LAT	9328.0
PCBP2	9322.0
TRIM32	9321.0
CD14	9315.0
CRK	9290.0
TREM2	9284.0
CEP290	9283.0
TRIM56	9246.0
GRN	9234.0
POLR2H	9192.0
DUSP3	9186.0
GMFG	9152.0
DEFB115	9127.0
ATP6V0A4	9075.0
SERPINB12	9068.0
EPPIN-WFDC6	9060.0
NCKIPSD	9056.0
PPP2R5D	9054.0
TBC1D10C	9036.0
HSPA6	9034.0
TNFAIP6	9022.0
CHI3L1	9011.0
PSMB9	9005.0
PLAC8	8984.0
WASF1	8983.0
CLEC4D	8963.0
JUN	8954.0
FCN3	8948.0
TMEM30A	8924.0
AAMP	8915.0
SLCO4C1	8876.0
PSMD4	8872.0
ATF1	8858.0
SRC	8847.0
DSN1	8846.0
PLPP4	8842.0
MAP2K1	8834.0
GRB2	8735.0
PSMD11	8704.0
SERPINA1	8698.0
CD36	8684.0
SLC2A5	8667.0
TARM1	8643.0
NLRP3	8642.0
NOD1	8634.0
NPC2	8623.0
RAB7A	8612.0
PGLYRP1	8566.0
BST1	8552.0
NAPRT	8550.0
SIRPB1	8549.0
NFKB1	8542.0
VAT1	8492.0
ARPC5	8474.0
TICAM1	8430.0
HLA-B	8428.0
PTGES2	8385.0
ACTR3	8378.0
FPR2	8365.0
GAB2	8360.0
DEFB116	8325.0
TUBB	8294.0
S100A7A	8292.0
ITGAL	8289.0
OLR1	8238.0
ARHGAP9	8230.0
FCAR	8205.0
POLR3H	8204.0
P2RX1	8200.0
SERPINB10	8146.0
ARL8A	8131.0
GM2A	8106.0
SIGLEC5	8103.0
ATP6V1D	8070.0
ITGAV	8060.0
PTPRC	8046.0
MALT1	7999.0
FAF2	7998.0
POLR3GL	7909.0
PPP3R1	7900.0
ATP6V0C	7898.0
POLR1C	7869.0
SURF4	7868.0
PADI2	7833.0
CPN1	7820.0
LCP2	7804.0
ACTR1B	7788.0
PA2G4	7738.0
PLCG1	7719.0
LPO	7715.0
SEM1	7709.0
C1R	7700.0
AHCYL1	7690.0
C3AR1	7631.0
PSMD12	7629.0
PIK3CA	7620.0
ELANE	7615.0
RELB	7533.0
B2M	7530.0
PRKACG	7521.0
DYNLL1	7506.0
C1QA	7493.0
SOS1	7452.0
JUP	7414.0
POLR3F	7410.0
DNM1	7382.0
POLR3C	7381.0
CTSH	7373.0
ATP6V1G1	7364.0
TRAF2	7332.0
HPSE	7325.0
QSOX1	7305.0
CD53	7248.0
VAPA	7224.0
MYO1C	7186.0
NLRP1	7171.0
ADGRE3	7167.0
TNFAIP3	7145.0
DYNC1H1	7135.0
KCNAB2	7127.0
LILRB3	7119.0
TSPAN14	7118.0
ART1	7101.0
SCAMP1	7098.0
TUBB4B	7088.0
AGER	7082.0
PRCP	7060.0
ATG12	7050.0
CSNK2B	6988.0
UNC13D	6941.0
STBD1	6883.0
DEFB136	6863.0
PSMC5	6830.0
PPP2CA	6783.0
AP1M1	6779.0
CLEC5A	6760.0
C1orf35	6756.0
C9	6750.0
PSMF1	6746.0
CDK13	6683.0
ABL1	6647.0
ITK	6638.0
CD44	6616.0
ATP6V1E1	6580.0
CALML5	6557.0
RNASE2	6545.0
CFH	6541.0
ARHGAP45	6524.0
PSMB1	6496.0
BCL2	6490.0
TEC	6483.0
PSMA4	6446.0
APAF1	6444.0
HSPA1A	6417.0
CAB39	6414.0
PSMA2	6356.0
UBC	6343.0
XRCC5	6340.0
MAP3K8	6299.0
BIRC3	6292.0
ATF2	6282.0
PGM2	6279.0
ATP6V1B1	6256.0
REG3A	6169.0
LRRC7	6164.0
DEFB128	6120.0
NCF2	6092.0
MUC16	6063.0
MUC13	6058.0
CAPZA1	6055.0
RAB37	6021.0
LBP	5989.0
CYBA	5968.0
MYH9	5929.0
FGA	5880.0
PLPP5	5856.0
GSTP1	5796.0
PGLYRP4	5781.0
WASL	5779.0
CR2	5776.0
PSMD3	5765.0
PSMA3	5711.0
PSMB8	5690.0
ACTR10	5676.0
NKIRAS2	5634.0
PPP3CB	5613.0
TREM1	5591.0
ENPP4	5543.0
DYNLT1	5528.0
COPB1	5520.0
RHOG	5476.0
ARPC3	5469.0
ADAM10	5459.0
POLR2E	5439.0
C2	5423.0
DYNC1LI1	5408.0
CCR2	5405.0
MRE11	5382.0
VAV2	5352.0
DEFB125	5318.0
C5	5264.0
MMP25	5232.0
MYD88	5218.0
NHLRC3	5212.0
TP53	5209.0
FTL	5208.0
CGAS	5197.0
ORMDL3	5188.0
IMPDH1	5177.0
PELI1	5117.0
BPIFA1	5111.0
RAB5C	5083.0
GUSB	5066.0
MUC4	5002.0
NOS3	5000.0
DOCK1	4988.0
DBNL	4983.0
XRCC6	4968.0
DEFB127	4957.0
A1BG	4949.0
ATP6V1G2	4942.0
PRKCSH	4899.0
MAPK11	4874.0
PTPN6	4836.0
TANK	4767.0
CREBBP	4677.0
CFL1	4665.0
EP300	4662.0
POLR3A	4653.0
CFI	4629.0
CRISPLD2	4618.0
CD58	4586.0
CD46	4561.0
RAP1A	4547.0
DNM3	4533.0
RAB18	4479.0
NLRC3	4474.0
NLRC4	4459.0
CRP	4458.0
TIMP2	4445.0
USP18	4438.0
MAPK9	4424.0
GLB1	4403.0
MAP3K7	4396.0
APP	4373.0
PTK2	4367.0
YES1	4285.0
CYFIP2	4278.0
DEFB133	4260.0
SDCBP	4199.0
IRAG2	4181.0
PSME3	4177.0
HSPA8	4148.0
CLEC10A	4142.0
ARSA	4138.0
MYO10	4135.0
NEU1	4126.0
IKBIP	4108.0
IRAK2	4085.0
BPIFB2	4063.0
EEF1A1	4031.0
RBSN	4017.0
PSMB6	3982.0
HMOX2	3975.0
DEFB129	3916.0
RAB4B	3914.0
CUL1	3869.0
PFKL	3854.0
FCN2	3828.0
HBB	3808.0
PRKACB	3804.0
ACLY	3791.0
COLEC11	3763.0
ITCH	3749.0
GCA	3731.0
BIN2	3690.0
PIK3R2	3686.0
UBE2D1	3677.0
ADA2	3676.0
DHX9	3672.0
PTPRB	3640.0
TCIRG1	3612.0
PAK2	3608.0
CTSB	3569.0
POLR1D	3539.0
BAIAP2	3508.0
PSAP	3439.0
ANO6	3403.0
CD59	3375.0
ITPR2	3351.0
C6	3308.0
ATP6V1A	3298.0
ABI2	3296.0
RAB44	3282.0
CTNNB1	3273.0
ECSIT	3240.0
RAB31	3171.0
GSDME	3168.0
ATP11A	3153.0
IFNA6	3146.0
MUC1	3144.0
ATP6V1H	3135.0
ERP44	3116.0
DEFB110	3102.0
C4BPB	3099.0
ADGRE5	3095.0
DDX41	3013.0
PSMD5	3011.0
SUGT1	2978.0
MNDA	2953.0
RAP1B	2941.0
ATP11B	2927.0
PSMB10	2924.0
CD55	2902.0
PSMB4	2895.0
PELI2	2890.0
MYO5A	2886.0
IDH1	2850.0
RNASET2	2838.0
DIAPH1	2829.0
SLC27A2	2825.0
LAT2	2802.0
P2RX7	2782.0
CLEC4E	2758.0
DHX58	2757.0
AP2A2	2753.0
IL1B	2714.0
LPCAT1	2713.0
EEF2	2688.0
SOCS1	2671.0
MAPK3	2655.0
LAMTOR3	2625.0
PPIA	2624.0
LRRC14	2617.0
FUCA2	2605.0
TAB2	2596.0
FADD	2580.0
LTA4H	2522.0
DNM2	2521.0
PSMA5	2491.0
ALPK1	2474.0
PSME1	2473.0
CARD9	2408.0
PIK3R1	2368.0
ROCK1	2365.0
PRDX6	2355.0
PSMD13	2253.0
CRACR2A	2225.0
CAP1	2222.0
MYO9B	2204.0
DOCK2	2193.0
PYGL	2184.0
BCL2L1	2167.0
PTPN4	2164.0
RAB24	2158.0
GALNS	2155.0
B4GALT1	2128.0
NCSTN	2123.0
POLR2F	2100.0
PLD1	2076.0
NFKB2	2075.0
TMEM179B	2066.0
NCKAP1L	2056.0
NOS2	2053.0
DSC1	2019.0
VAV1	2015.0
SFTPA1	1974.0
STING1	1894.0
SIGLEC14	1891.0
TRAF3	1880.0
LY86	1830.0
TICAM2	1828.0
ATG7	1821.0
POLR2L	1774.0
NFATC1	1736.0
VCL	1732.0
PIK3CB	1713.0
NOD2	1711.0
HSP90B1	1619.0
CYSTM1	1606.0
PECAM1	1596.0
RAB5B	1594.0
CPNE1	1584.0
SPTAN1	1571.0
TXNDC5	1550.0
GOLGA7	1547.0
AMPD3	1535.0
HTN1	1503.0
IGF2R	1501.0
CHRNB4	1483.0
TRIM25	1464.0
CFB	1422.0
DNAJC5	1418.0
RHOA	1411.0
SIGIRR	1396.0
FOS	1357.0
ATP6V1F	1344.0
CXCR2	1315.0
CST3	1291.0
LAMTOR2	1290.0
ATG5	1253.0
CD300A	1246.0
ABI1	1230.0
TXNIP	1203.0
ALDH3B1	1172.0
RAF1	1162.0
ATP6V0E1	1095.0
PSMD6	1064.0
HEXB	1024.0
PSMD9	970.0
RIPK2	959.0
ATP6V1C1	946.0
UBE2K	899.0
CFHR4	833.0
RAB10	829.0
ATP6V0B	819.0
C8G	805.0
RELA	786.0
MGAM	784.0
CCT8	756.0
CPB2	746.0
CR1	735.0
PIK3R4	705.0
CCL17	665.0
CCR6	652.0
UBE2D2	629.0
CTSC	622.0
PLAU	614.0
MAPK7	605.0
WIPF2	599.0
PLAUR	579.0
DEFB134	565.0
GSN	553.0
MAVS	522.0
PTPN11	498.0
CD47	492.0
ITPR1	482.0
MAPKAPK3	467.0
NCK1	461.0
IFNA13	436.0
RAB3A	434.0
HSP90AA1	431.0
RAB14	409.0
CAPN1	407.0
FCER1A	399.0
RPS6KA1	327.0
RNF135	273.0
POLR3K	247.0
SIGLEC15	228.0
PSMD8	214.0
KCMF1	207.0
CD81	168.0
S100A11	161.0
ACAA1	160.0
DUSP4	139.0
PSMB5	136.0
PDAP1	125.0
DEFB1	123.0
UNC93B1	109.0
TMBIM1	107.0
CEACAM3	100.0
ARPC4	84.0
UBE2D3	81.0
NKIRAS1	51.0
FGG	38.0
IST1	37.0
ICAM2	35.0
CFD	11.0
PGLYRP2	10.0
PROS1	5.0
SIKE1	-4.0
TOLLIP	-10.0
MYH2	-44.0
SELL	-53.0
RIPK3	-105.0
BRK1	-131.0
RPS6KA2	-209.0
ATOX1	-213.0
ACTR2	-261.0
PPP3CA	-309.0
CDC42	-333.0
PSMA7	-337.0
PSME4	-360.0
PSMC1	-363.0
CHUK	-404.0
TNFRSF1B	-481.0
BCL10	-494.0
HMGB1	-505.0
CASP9	-544.0
TNIP2	-560.0
IFNA8	-567.0
CFHR5	-575.0
IRF7	-638.0
PRKCQ	-647.0
ARSB	-658.0
RNF216	-674.0
HK3	-686.0
VTN	-729.0
BIRC2	-747.0
PTPRN2	-753.0
NME2	-765.0
C1S	-794.0
RAB6A	-806.0
MMP9	-839.0
MAP2K3	-854.0
MAPK10	-868.0
QPCT	-873.0
ABCA13	-878.0
SLC44A2	-880.0
MAP3K1	-897.0
HSPA1B	-917.0
PLA2G6	-926.0
TMEM63A	-931.0
ELMO1	-969.0
IFI16	-1044.0
LTF	-1055.0
C6orf120	-1066.0
DPP7	-1093.0
PPIE	-1129.0
PLD2	-1144.0
FBXW11	-1153.0
ATP8A1	-1167.0
SFTPD	-1179.0
ANXA2	-1204.0
YPEL5	-1205.0
POLR3G	-1235.0
TOM1	-1244.0
CAND1	-1248.0
UBB	-1252.0
SEMG1	-1259.0
SNAP25	-1294.0
GYG1	-1334.0
PRKCE	-1346.0
C8B	-1354.0
EEA1	-1424.0
ATP6V0A1	-1427.0
FGR	-1486.0
PSMA6	-1500.0
BPI	-1549.0
MUC7	-1552.0
NCR2	-1559.0
ZBP1	-1576.0
POLR3D	-1583.0
PKM	-1597.0
PRKDC	-1645.0
SNAP29	-1654.0
CNN2	-1659.0
CANT1	-1675.0
ATP8B4	-1690.0
MUC17	-1702.0
ILF2	-1723.0
RASGRP1	-1742.0
MAPK14	-1781.0
BPIFB1	-1787.0
NF2	-1788.0
AHSG	-1793.0
MEF2A	-1822.0
TAX1BP1	-1856.0
DUSP7	-1866.0
STOM	-1875.0
AGL	-1902.0
GAA	-1931.0
APEH	-1945.0
PIN1	-1952.0
ITGB2	-1999.0
WASF2	-2003.0
SKP1	-2012.0
IFNA1	-2016.0
C3	-2020.0
HEBP2	-2046.0
LGALS3	-2056.0
FRK	-2070.0
LYN	-2080.0
GGH	-2110.0
MAP2K6	-2128.0
GHDC	-2162.0
HCK	-2180.0
PSMC6	-2235.0
ALDOA	-2245.0
ARPC1B	-2247.0
VPS35L	-2342.0
VRK3	-2353.0
CREB1	-2363.0
HLA-C	-2367.0
RPS6KA5	-2374.0
WIPF1	-2379.0
DHX36	-2413.0
SAA1	-2421.0
ATP6V1B2	-2437.0
PSMB2	-2499.0
BTRC	-2541.0
DNAJC13	-2558.0
MIF	-2566.0
DUSP6	-2575.0
LAMTOR1	-2576.0
MUC15	-2578.0
SYNGR1	-2656.0
FYN	-2742.0
ITGAM	-2757.0
PSMD14	-2853.0
LILRA3	-2856.0
PGM1	-2871.0
PSME2	-2879.0
CTSK	-2891.0
LY96	-2897.0
AGPAT2	-2917.0
IMPDH2	-2929.0
DTX4	-2942.0
PNP	-2960.0
DGAT1	-2983.0
F2	-2987.0
VAMP8	-2991.0
UBE2L6	-2994.0
PIGR	-2996.0
CLEC12A	-3002.0
IRAK3	-3008.0
CD180	-3030.0
VAV3	-3032.0
PDXK	-3038.0
VCP	-3112.0
CYLD	-3119.0
MAPK1	-3138.0
TXN	-3153.0
DNAJC3	-3168.0
PSMC2	-3243.0
RNF125	-3257.0
PSMD1	-3280.0
AGA	-3285.0
PLCG2	-3296.0
PAK1	-3300.0
TRAPPC1	-3308.0
ACTG1	-3326.0
NFATC3	-3327.0
DEFA6	-3345.0
KLRK1	-3346.0
ACTB	-3347.0
CPPED1	-3350.0
CYB5R3	-3426.0
ATP6V1G3	-3437.0
POLR2K	-3444.0
IKBKB	-3448.0
PTAFR	-3454.0
DSP	-3511.0
PPP2R1A	-3530.0
RAB3D	-3561.0
USP14	-3590.0
UBE2V1	-3648.0
ARPC2	-3716.0
TRPM2	-3728.0
MAP3K14	-3735.0
NFKBIB	-3742.0
WIPF3	-3755.0
CKAP4	-3765.0
WASF3	-3796.0
NOS1	-3806.0
ALAD	-3835.0
PIK3C3	-3838.0
KRAS	-3860.0
TRAF6	-3915.0
IFNA5	-3957.0
IKBKE	-3971.0
POLR3B	-3991.0
TLR6	-4038.0
MEF2C	-4058.0
PSMB3	-4168.0
NCKAP1	-4182.0
CYFIP1	-4193.0
ATP6V1C2	-4210.0
NLRP4	-4250.0
MLEC	-4253.0
HMOX1	-4254.0
PYCARD	-4258.0
CRISP3	-4271.0
CALM1	-4297.0
MUCL1	-4351.0
GPR84	-4356.0
PLD3	-4375.0
CXCL1	-4382.0
MASP1	-4399.0
CREG1	-4432.0
ITPR3	-4436.0
IRF3	-4456.0
PGAM1	-4486.0
HERC5	-4496.0
BPIFA2	-4515.0
REG3G	-4615.0
DEFB123	-4625.0
ATAD3B	-4661.0
SIGLEC9	-4700.0
DERA	-4731.0
CMTM6	-4763.0
OSTF1	-4766.0
PRKACA	-4802.0
LRRFIP1	-4811.0
IQGAP2	-4832.0
CARD11	-4843.0
PSMD7	-4907.0
KPNB1	-4921.0
TLR5	-4930.0
ALOX5	-4986.0
FGL2	-5002.0
CD63	-5007.0
RAP2B	-5017.0
PSEN1	-5034.0
STK11IP	-5076.0
IQGAP1	-5089.0
ACP3	-5106.0
MAN2B1	-5111.0
FGB	-5150.0
PAFAH1B2	-5169.0
NFASC	-5178.0
MAP2K4	-5206.0
SRP14	-5210.0
SERPINB1	-5221.0
POLR3E	-5271.0
PPP2R1B	-5288.0
LAMP1	-5289.0
CAMP	-5348.0
ATP6V0D1	-5365.0
GLIPR1	-5376.0
ORM2	-5464.0
NBEAL2	-5468.0
C7	-5525.0
CRCP	-5569.0
CLU	-5590.0
SVIP	-5616.0
C5AR1	-5643.0
PSMC4	-5662.0
IRAK4	-5699.0
CASP8	-5739.0
CSTB	-5754.0
CD300LB	-5757.0
COTL1	-5774.0
ARPC1A	-5814.0
BRI3	-5835.0
CHGA	-5872.0
TXK	-5880.0
ADAM8	-5908.0
CASP4	-5932.0
SNAP23	-5935.0
ELMO2	-5982.0
DEFB121	-5987.0
ATP6V0A2	-6035.0
NFKBIA	-6060.0
MUC21	-6083.0
UBR4	-6084.0
DDOST	-6114.0
STK10	-6226.0
ARMC8	-6234.0
FCER1G	-6239.0
RAC1	-6271.0
HGSNAT	-6299.0
BPIFB4	-6305.0
MAP2K7	-6310.0
TLR3	-6318.0
DEFB135	-6336.0
FTH1	-6401.0
SERPINB6	-6402.0
ITLN1	-6425.0
HLA-A	-6482.0
STAT6	-6489.0
BPIFB6	-6599.0
HSP90AB1	-6618.0
CNPY3	-6639.0
PDPK1	-6640.0
ASAH1	-6646.0
FLG2	-6651.0
KRT1	-6702.0
MUC20	-6705.0
GPI	-6710.0
SARM1	-6745.0
MME	-6816.0
NDUFC2	-6833.0
TREX1	-6846.0
MAPK13	-6897.0
PSMA8	-6922.0
CDC34	-6928.0
OSCAR	-6937.0
CD247	-6962.0
IFNA7	-6973.0
CLEC7A	-6995.0
SLC15A4	-7037.0
MUC6	-7044.0
TAB1	-7049.0
LIMK1	-7066.0
COMMD3	-7070.0
CASP2	-7081.0
TIRAP	-7106.0
PSMD2	-7108.0
DEFA5	-7126.0
PKP1	-7158.0
PRSS3	-7235.0
PSMB11	-7246.0
SFTPA2	-7250.0
SERPINB3	-7285.0
CASP1	-7326.0
BST2	-7328.0
LAIR1	-7336.0
NFATC2	-7353.0
PLD4	-7375.0
MAPK12	-7390.0
MANBA	-7398.0
PLEKHO2	-7476.0
LGMN	-7513.0
CCT2	-7524.0
DEFB118	-7525.0
VNN1	-7543.0
MAPK8	-7610.0
COMMD9	-7656.0
TIFA	-7657.0
MUC3A	-7694.0
SYK	-7713.0
EPPIN	-7715.0
C4BPA	-7734.0
RIPK1	-7765.0
CD4	-7809.0
PELI3	-7876.0
APOB	-7916.0
N4BP1	-7978.0
UBA52	-8028.0
RIGI	-8108.0
LYZ	-8122.0
RNASE7	-8126.0
PTX3	-8150.0
NLRX1	-8234.0
CTSS	-8247.0
RASGRP4	-8249.0
TLR1	-8253.0
CTSD	-8287.0
PPP2CB	-8320.0
CASP10	-8352.0
TRIM4	-8375.0
S100A1	-8381.0
DEFB126	-8397.0
LEAP2	-8461.0
CTSZ	-8560.0
UBA3	-8593.0
TLR2	-8600.0
LILRB2	-8639.0
MUC12	-8673.0
IFNA14	-8752.0
CAPZA2	-8799.0
MUC5B	-8828.0
TYROBP	-8832.0
FCGR2A	-8842.0
HRAS	-8845.0
CLEC4C	-8883.0
MS4A2	-8964.0
PRG2	-9040.0
KLRD1	-9103.0
ALDOC	-9111.0
CD19	-9130.0
DEFB104A	-9144.5
DEFB104B	-9144.5
GZMM	-9154.0
CPNE3	-9161.0
UBE2M	-9176.0
MCEMP1	-9193.0
CTSL	-9215.0
CTSV	-9225.0
MASP2	-9233.0
FUCA1	-9247.0
UBA7	-9302.0
TLR4	-9342.0
TRIM21	-9367.0
CLEC4A	-9595.0
C8A	-9600.0
EPX	-9636.0
FPR1	-9651.0
MMP8	-9690.0
C4A	-9764.5
C4B	-9764.5
C1QB	-9830.0
ATP6V0E2	-9852.0
GNLY	-9942.0
IFNA2	-9962.0
FCGR3A	-9996.0

---

REACTOME_GLUCURONIDATION

REACTOME_GLUCURONIDATION

	146
set	REACTOME_GLUCURONIDATION
setSize	23
pANOVA	0.000668
s.dist	0.41
p.adjustANOVA	0.0512

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UGT2B7	11819
ABHD10	11317
UGT2A1	9703
UGT2B15	9450
UGT2B4	9241
UGT1A5	8133
UGT2A3	7910
UGT1A1	7778
UGT1A3	7679
UGT2B11	7510
UGT1A4	7508
UGT3A1	6728
UGT1A6	5809
UGT2B17	5633
UGP2	4343
UGT1A9	3580
UGT1A7	3316
UGT2A2	2278
UGT1A10	1717
UGT3A2	1297

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UGT2B7	11819
ABHD10	11317
UGT2A1	9703
UGT2B15	9450
UGT2B4	9241
UGT1A5	8133
UGT2A3	7910
UGT1A1	7778
UGT1A3	7679
UGT2B11	7510
UGT1A4	7508
UGT3A1	6728
UGT1A6	5809
UGT2B17	5633
UGP2	4343
UGT1A9	3580
UGT1A7	3316
UGT2A2	2278
UGT1A10	1717
UGT3A2	1297
UGT1A8	1210
SLC35D1	-1933
UGDH	-6047

---

REACTOME_GPCR_LIGAND_BINDING

REACTOME_GPCR_LIGAND_BINDING

	834
set	REACTOME_GPCR_LIGAND_BINDING
setSize	444
pANOVA	0.000686
s.dist	-0.094
p.adjustANOVA	0.0512

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
HTR1B	-9733
CRHBP	-9709
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
GNG11	-9535
DRD4	-9509
CCL3	-9424
TAAR1	-9393
CX3CR1	-9364
SCT	-9338
CXCL6	-9329
LHB	-9239
GPRC6A	-9210

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
HTR1B	-9733
CRHBP	-9709
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
GNG11	-9535
DRD4	-9509
CCL3	-9424
TAAR1	-9393
CX3CR1	-9364
SCT	-9338
CXCL6	-9329
LHB	-9239
GPRC6A	-9210
TAS2R1	-9199
NPFFR1	-9194
QRFP	-9192
CCL13	-9113
TAS2R9	-9080
SUCNR1	-9072
CCR9	-9065
GHSR	-8961
MC2R	-8873
LPAR3	-8870
TAS2R4	-8864
TAS2R20	-8858
GPHB5	-8829
AVPR1A	-8819
GNG3	-8811
HTR1F	-8746
SMO	-8725
LHCGR	-8718
F2RL3	-8689
PTGDR2	-8617
CCKBR	-8605
SSTR1	-8587
PNOC	-8520
BDKRB2	-8462
GPR183	-8429
DRD1	-8427
NTSR2	-8417
PENK	-8412
NPW	-8391
OXER1	-8367
ADRA2C	-8289
TAAR8	-8260
CCL2	-8259
FFAR2	-8246
GHRHR	-8133
GNAS	-8089
IAPP	-8075
WNT9B	-8006
F2RL2	-7963
CHRM1	-7959
TRH	-7860
PLPPR4	-7769
LPAR2	-7759
KNG1	-7708
PTCH2	-7630
CXCL5	-7575
HTR4	-7546
FSHB	-7506
CASR	-7479
NPSR1	-7436
CXCL2	-7434
HRH3	-7422
EDNRB	-7418
CCR3	-7362
NPB	-7330
CRHR2	-7314
SSTR5	-7286
P2RY14	-7240
IHH	-7233
OPRK1	-7224
TAS2R30	-7096
MC3R	-7082
ADRB1	-7036
FPR3	-6979
RAMP2	-6893
NPY5R	-6836
FZD10	-6776
CXCL3	-6674
FZD9	-6642
GRP	-6577
RXFP2	-6553
PROK2	-6543
GNG2	-6513
AGT	-6496
TAS2R41	-6486
ADRA2B	-6460
HTR1A	-6448
FZD8	-6412
MC5R	-6393
F2RL1	-6352
GNG8	-6304
CRHR1	-6246
S1PR3	-6052
ADCYAP1	-6045
PTGER2	-5957
GPR37	-5949
CCK	-5936
ECE2	-5916
TAS2R60	-5883
WNT5A	-5855
ADRB3	-5794
TAS2R39	-5716
C5AR1	-5643
WNT10A	-5578
UCN2	-5572
CNR1	-5521
DRD5	-5517
OPRL1	-5467
XCL1	-5458
HTR1E	-5408
SHH	-5395
TAC3	-5384
PMCH	-5352
ADGRE1	-5329
ACKR3	-5252
MC4R	-5196
S1PR5	-5183
NPY	-4972
GLP2R	-4961
RLN2	-4892
PYY	-4866
GALR2	-4819
RGR	-4762
GNG4	-4676
CCKAR	-4576
PF4	-4561
NTS	-4550
CXCL9	-4384
CXCL1	-4382
SSTR2	-4331
TAC1	-4300
VIP	-4263
TSHR	-4219
NPY1R	-4217
CCR4	-4092
NMBR	-4040
CALCA	-4028
ADGRE2	-3981
CGA	-3774
PROKR2	-3770
SCTR	-3758
CHRM2	-3732
RRH	-3710
PRLH	-3698
HTR5A	-3625
WNT7B	-3623
WNT16	-3607
PDYN	-3573
NPBWR1	-3513
PTAFR	-3454
KISS1	-3425
MC1R	-3415
CCL27	-3389
DRD2	-3335
ADRA1D	-3333
GNB4	-3317
NMUR2	-3305
TBXA2R	-3273
WNT3	-3083
TACR1	-3078
F2	-2987
GRM6	-2963
FZD6	-2945
CCL21	-2911
ADORA2B	-2857
UTS2R	-2818
LTB4R2	-2765
HTR7	-2583
TACR2	-2572
OPN1SW	-2569
CCL1	-2524
TAAR9	-2520
MCHR2	-2459
PRLHR	-2446
SAA1	-2421
CCR10	-2415
TAS2R46	-2398
CNR2	-2331
WNT11	-2321
GPR35	-2298
PTH2R	-2236
GALR1	-2199
CALCR	-2192
RXFP1	-2187
ADORA1	-2159
CMKLR1	-2124
HRH1	-2107
S1PR1	-2049
GNGT2	-2033
C3	-2020
PLPPR1	-1914
PTGFR	-1907
GPR65	-1893
ADRA2A	-1881
LPAR5	-1878
ADCYAP1R1	-1798
GNG5	-1791
PTHLH	-1718
GHRL	-1640
CALCB	-1466
EDN1	-1439
MTNR1A	-1391
AVPR1B	-1377
CCL20	-1355
WNT3A	-1292
TAS2R50	-1278
PTH2	-934
GNRH2	-928
CHRM4	-805
FZD5	-780
TAS2R42	-596
CCL7	-373
CXCL11	-362
PTGDR	-330
TAS1R1	-169
ADRA1A	-117
INSL3	-102
TAS1R2	-82
F2R	-64
ADM2	-38
DHH	-32
WNT2B	-23
LPAR1	2
WNT8B	34
FFAR4	43
GRM8	60
WNT6	101
OXTR	177
HCRTR2	307
ANXA1	317
GIPR	423
P2RY1	466
WNT2	563
OPN3	612
CCR6	652
GRM4	660
CCL17	665
TAAR2	715
HEBP1	734
FZD3	774
MLNR	974
TAS1R3	1006
CHRM5	1034
GNGT1	1092
CX3CL1	1309
CXCR2	1315
TAAR5	1478
WNT7A	1485
CCRL2	1587
LTB4R	1655
P2RY6	1785
CCL28	1840
GRM3	1861
GPR4	1912
WNT10B	1930
P2RY2	2030
OPN4	2142
RAMP1	2149
GRM7	2283
RHO	2339
FZD1	2350
CXCL12	2377
POMC	2442
SSTR4	2447
TRHR	2481
GRM1	2517
CXCR5	2559
CXCL16	2585
VIPR1	2623
HTR2B	2657
NPBWR2	2695
MTNR1B	2778
NLN	2828
FSHR	2866
CD55	2902
PTH1R	2910
OPRM1	2959
CYSLTR2	2960
GNB5	3005
EDNRA	3083
OPN5	3091
ADGRE5	3095
TAS2R16	3096
ADORA3	3157
DRD3	3276
PTCH1	3291
PTGER1	3421
PSAP	3439
NPFFR2	3466
KISS1R	3494
GNG12	3495
GNB1	3572
GABBR1	3717
VIPR2	3738
WNT1	3764
GPBAR1	3771
GPR39	3803
HTR6	3830
NTSR1	3935
EDN2	3955
FZD4	4117
CCL25	4222
NPY2R	4267
CHRM3	4282
FFAR3	4288
GNG13	4294
OXGR1	4348
APP	4373
NMU	4395
GAL	4498
GNRH1	4544
ADRB2	4580
APLNR	4597
FZD2	4648
HCRT	4651
HRH2	4710
UCN3	4752
P2RY12	4796
LPAR6	4805
GNB2	4816
QRFPR	4841
CCL19	4861
HCRTR1	5129
TAAR6	5202
C5	5264
GNRHR	5384
CCR2	5405
PPY	5443
WNT4	5526
GNG7	5612
CRH	5702
EDN3	5710
SSTR3	5832
PLPPR5	5858
GABBR2	5898
ECE1	5927
TAS2R5	6093
GPR18	6242
BDKRB1	6284
CALCRL	6302
WNT9A	6305
ADRA1B	6306
TAS2R14	6314
S1PR2	6429
GRM5	6438
GPER1	6584
RLN3	6629
P2RY13	6769
CXCL13	6801
SST	6854
RXFP3	6888
S1PR4	6898
CCR7	6943
AGTR1	7083
CCL23	7130
ADGRE3	7167
UTS2B	7264
OPRD1	7367
FZD7	7419
ACKR2	7532
NMB	7627
C3AR1	7631
GNG10	7743
PLPPR2	7836
TACR3	7850
RXFP4	7941
GPHA2	8011
GLP1R	8067
PTGER4	8119
NPS	8137
INSL5	8151
PROK1	8216
TAS2R8	8221
CCR8	8322
FPR2	8365
KEL	8495
GPR132	8525
CXCR4	8636
UTS2	8723
ADM	8734
HCAR1	8744
TAS2R7	8800
PTGER3	8962
TSHB	8993
HRH4	9052
UCN	9082
TAS2R10	9254
GHRH	9294
ACKR4	9303
RAMP3	9313
HTR1D	9411
GRM2	9506
CCL22	9532
TAS2R43	9562
PROKR1	9925
PLPPR3	9947
CCR5	9973
TAS2R3	9988
GALR3	10003
GPR68	10013
GCG	10041
NPFF	10161
HTR2A	10279
NMS	10299
GPR31	10372
PTH	10420
XCR1	10451
CCL5	10503
GPR37L1	10512
GPR55	10554
CORT	10574
GIP	10790
C5AR2	10793
CCR1	10817
GPR17	10822
TAS2R38	10888
TAS2R13	11061
CXCR6	11068
FFAR1	11077
CXCR1	11116
TAS2R40	11128
GNB3	11194
TAS2R31	11335
CCL16	11358
HCAR2	11415
WNT8A	11455
P2RY11	11466
ACKR1	11493
MCHR1	11497
TAS2R19	11510
ADORA2A	11523
CCL11	11530
PPBP	11551
PTGIR	11596

---

REACTOME_INTERLEUKIN_18_SIGNALING

REACTOME_INTERLEUKIN_18_SIGNALING

	1366
set	REACTOME_INTERLEUKIN_18_SIGNALING
setSize	8
pANOVA	0.000757
s.dist	-0.688
p.adjustANOVA	0.054

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IL13	-9974
IL37	-8157
IL18RAP	-7922
IL18	-7429
IL4	-5369
ALOX5	-4986
IL18R1	-4776
IL18BP	-4109

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IL13	-9974
IL37	-8157
IL18RAP	-7922
IL18	-7429
IL4	-5369
ALOX5	-4986
IL18R1	-4776
IL18BP	-4109

---

REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

	447
set	REACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX
setSize	21
pANOVA	0.000815
s.dist	0.422
p.adjustANOVA	0.0545

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP4F8	10772
CYP4F2	10550
LTC4S	10057
ALOX5AP	9931
CYP4F11	9821
MAPKAPK2	9627
GGT5	8942
CYP4B1	7064
DPEP2	6912
ABCC1	6525
DPEP3	6085
CYP4F3	5708
GGT1	5145
LTA4H	2522
DPEP1	2302
CYP4F22	1466
ALOX5	-4986
PTGR1	-5310

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP4A11	11830
CYP4A22	11687
CYP4F8	10772
CYP4F2	10550
LTC4S	10057
ALOX5AP	9931
CYP4F11	9821
MAPKAPK2	9627
GGT5	8942
CYP4B1	7064
DPEP2	6912
ABCC1	6525
DPEP3	6085
CYP4F3	5708
GGT1	5145
LTA4H	2522
DPEP1	2302
CYP4F22	1466
ALOX5	-4986
PTGR1	-5310
ALOX15	-8814

---

REACTOME_HIV_INFECTION

REACTOME_HIV_INFECTION

	175
set	REACTOME_HIV_INFECTION
setSize	223
pANOVA	0.000829
s.dist	0.13
p.adjustANOVA	0.0545

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
LCK	11410
NUP85	11204
TAF12	11000
ELOC	10913
PSMC3	10873
RCC1	10651
CHMP3	10347
CD8B	10307
PSMB7	10268
PSMA1	10105
TAF9	10000
CCR5	9973
RAE1	9805
RANBP2	9739
UBAP1	9668
CTDP1	9550
RPS27A	9528
POLR2D	9470
PDCD6IP	9381

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527
LCK	11410
NUP85	11204
TAF12	11000
ELOC	10913
PSMC3	10873
RCC1	10651
CHMP3	10347
CD8B	10307
PSMB7	10268
PSMA1	10105
TAF9	10000
CCR5	9973
RAE1	9805
RANBP2	9739
UBAP1	9668
CTDP1	9550
RPS27A	9528
POLR2D	9470
PDCD6IP	9381
TBP	9369
TAF11	9352
CCNT2	9318
NPM1	9297
SLC25A4	9201
POLR2H	9192
AP1B1	9144
PSIP1	9118
PSMB9	9005
PSMD4	8872
XPO1	8796
GTF2H3	8733
PSMD11	8704
POM121C	8691
CXCR4	8636
ARF1	8590
POLR2C	8572
TAF6	8521
GTF2E1	8409
ELOA2	8183
TCEA1	8153
NEDD4L	8078
FEN1	8054
NUP37	7970
VPS4B	7958
POLR2G	7857
SEM1	7709
PSMD12	7629
BANF1	7555
B2M	7530
TAF4	6968
NCBP2	6845
PSMC5	6830
AP1M1	6779
PSMF1	6746
TAF10	6586
NUP42	6550
SSRP1	6511
PSMB1	6496
PSMA4	6446
GTF2F2	6404
NUP58	6384
PSMA2	6356
RNMT	6346
UBC	6343
XRCC5	6340
VPS4A	6257
ELL	6195
NUP107	6064
VPS37C	5978
RAN	5942
LIG4	5805
GTF2H4	5769
PSMD3	5765
CDK9	5746
PSMA3	5711
PSMB8	5690
POLR2E	5439
AP1S1	5427
TAF2	5347
NDC1	5235
POM121	5192
TAF4B	5147
AAAS	5126
RANGAP1	5116
XRCC6	4968
MVB12B	4953
AP1M2	4870
APOBEC3G	4666
XRCC4	4622
NUP88	4471
NMT1	4226
TPR	4207
PSME3	4177
SEH1L	4175
MNAT1	4149
AP1S3	4112
PSMB6	3982
KPNA1	3685
PAK2	3608
TAF7	3463
CCNT1	3440
NCBP1	3154
ATP6V1H	3135
PSMD5	3011
GTF2B	2966
PSMB10	2924
PSMB4	2895
CHMP6	2856
NUP62	2832
GTF2E2	2797
SUPT5H	2754
AP2A2	2753
PPIA	2624
NUP205	2621
HMGA1	2615
PSMA5	2491
PSME1	2473
PSMD13	2253
AP2S1	2236
DOCK2	2193
POLR2F	2100
GTF2H5	2062
AP1G1	1866
RANBP1	1846
TSG101	1834
POLR2L	1774
NUP188	1699
CHMP7	1243
NUP214	1239
PSMD6	1064
GTF2F1	1054
NUP153	1016
NELFE	1008
PSMD9	970
NUP43	847
CHMP5	822
NUP93	637
VPS37A	560
SUPT4H1	555
TAF3	552
NUP210	420
LIG1	232
PSMD8	214
POLR2A	197
NUP54	148
PSMB5	136
AP2A1	-132
PSMA7	-337
PSME4	-360
PSMC1	-363
SUPT16H	-743
CCNK	-772
ELMO1	-969
VPS37B	-974
TAF15	-1029
CHMP4A	-1080
ELOA	-1162
UBB	-1252
PSMA6	-1500
TAF5	-1527
NUP133	-1680
MVB12A	-1772
CD28	-1842
CHMP2B	-2000
SKP1	-2012
VPS28	-2086
GTF2H1	-2130
CDK7	-2166
POLR2B	-2172
HCK	-2180
PSMC6	-2235
PSMB2	-2499
BTRC	-2541
VTA1	-2561
RNGTT	-2718
FYN	-2742
PSMD14	-2853
NUP50	-2854
PSME2	-2879
ERCC2	-3009
CCNH	-3092
AP2B1	-3170
PSMC2	-3243
PSMD1	-3280
POLR2K	-3444
CHMP4B	-3579
NELFA	-3580
GTF2A1	-3596
PACS1	-3933
CHMP2A	-4010
CUL5	-4020
NUP98	-4024
PSMB3	-4168
NELFB	-4446
FURIN	-4675
PSMD7	-4907
KPNB1	-4921
NMT2	-4979
ELOB	-4985
NUP155	-5088
RBX1	-5229
AP2M1	-5421
ERCC3	-5552
NELFCD	-5624
PSMC4	-5662
NUP160	-5917
RAC1	-6271
NUP35	-6288
POLR2I	-6444
HLA-A	-6482
PSMA8	-6922
CD247	-6962
PSMD2	-7108
GTF2A2	-7181
CHMP4C	-7232
PSMB11	-7246
TAF13	-7341
VPS37D	-7721
CD4	-7809
UBA52	-8028
TAF1L	-8151
POLR2J	-9903

---

REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING

	1148
set	REACTOME_RRNA_PROCESSING
setSize	192
pANOVA	0.000949
s.dist	0.138
p.adjustANOVA	0.0599

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
EXOSC6	11380
RPS11	11368
RPL10L	10992
PWP2	10963
RPL17	10955
MPHOSPH10	10887
RPL23A	10886
UTP3	10867
RPLP2	10866
RRP7A	10857
RPL12	10805
RBM28	10560
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
ISG20L2	10194
RPL18	9942

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
EXOSC6	11380.0
RPS11	11368.0
RPL10L	10992.0
PWP2	10963.0
RPL17	10955.0
MPHOSPH10	10887.0
RPL23A	10886.0
UTP3	10867.0
RPLP2	10866.0
RRP7A	10857.0
RPL12	10805.0
RBM28	10560.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
ISG20L2	10194.0
RPL18	9942.0
RPL34	9922.0
UTP11	9870.0
PRORP	9792.0
MTERF4	9729.0
EMG1	9630.0
RPS27A	9528.0
TRMT112	9499.0
RPL22L1	9418.0
ERI1	9345.0
UTP4	9327.0
RPL28	9256.0
DDX21	9252.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
NOP58	8449.0
UTP15	8413.0
RPL13A	8411.5
TFB1M	8274.0
ELAC2	8265.0
RPS19	8143.0
RPL22	7968.0
RPS7	7735.0
NSUN4	7722.0
RPS29	7569.0
NAT10	7479.0
NIP7	7441.0
RPS12	7345.0
NOP56	7202.0
FTSJ3	7033.0
BUD23	6982.0
EXOSC4	6732.0
RPL24	6708.0
KRR1	6624.0
RPS3	6559.0
RPSA	6342.0
DHX37	6310.0
RPP40	6171.0
WDR46	6042.0
NOP10	6036.0
EXOSC10	6028.0
RRP36	5995.0
RPS27	5993.0
RPL37A	5921.0
RPS6	5661.0
HEATR1	5393.0
UTP20	5330.0
THUMPD1	5276.0
NCL	5265.0
RPS15A	5190.0
BOP1	5062.0
NOL11	4980.0
PNO1	4799.0
XRN2	4628.0
RPS5	4600.0
PDCD11	4588.0
WDR36	4560.0
RPL18A	4496.0
FCF1	4398.0
RPS3A	4153.0
RPP14	3946.0
RIOK1	3887.0
EXOSC3	3872.0
IMP4	3757.0
RPL38	3648.0
DDX49	3438.0
RPL15	3368.0
TEX10	3106.0
MRM3	3079.0
MTREX	2962.0
RPL3L	2883.0
SENP3	2604.0
DIMT1	2544.0
RPS9	2500.0
DIS3	2407.0
RPS2	2297.0
RPL26L1	2230.0
MRM2	2210.0
RPL31	2159.0
RPL3	1947.0
SNU13	1938.0
RPL36	1899.0
GAR1	1832.0
RRP1	1432.0
PES1	1250.0
RPS27L	1225.0
WDR3	1202.0
UTP18	1175.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
RPL26	511.0
EXOSC9	418.0
RPS10	340.0
WDR75	167.0
NOC4L	162.0
RPL39L	118.0
RPL27A	-207.0
UTP6	-238.0
RPL23	-246.0
RPL35	-273.0
WDR18	-285.0
WDR43	-525.0
RPS20	-996.0
TSR1	-1117.0
EBNA1BP2	-1222.0
RPL36AL	-1282.5
UTP25	-1481.0
NOL6	-1630.0
RIOK2	-1734.0
RPP30	-1737.0
GNL3	-1810.0
BMS1	-1816.0
RRP9	-1846.0
DDX52	-2027.0
RPL9	-2057.0
BYSL	-2133.0
UTP14C	-2171.0
RPL37	-2213.0
NOL9	-2216.0
RPS26	-2447.0
RPS16	-2774.0
NOP2	-3070.0
RPP38	-3204.0
CSNK1D	-3900.0
WDR12	-3964.0
EXOSC1	-3977.0
PELP1	-3985.0
RPL6	-3988.0
TRMT10C	-4174.0
LTV1	-4230.0
RPL11	-4362.0
NHP2	-4376.0
RPS15	-4410.0
EXOSC2	-4552.0
NOP14	-4686.0
RPL32	-4713.0
RPS25	-4757.0
RPLP1	-5104.0
RPL21	-5327.0
MPHOSPH6	-5417.0
RPL19	-5474.0
EXOSC8	-5555.0
EXOSC7	-6133.0
DDX47	-6151.0
NOB1	-6276.0
IMP3	-6361.0
RPP25	-6484.0
RPL27	-6794.0
CSNK1E	-6804.0
MRM1	-7052.0
RPP21	-7147.0
C1D	-7407.0
RPS28	-7410.0
DCAF13	-7581.0
FBL	-7616.0
RPS21	-7890.0
UBA52	-8028.0
RCL1	-8291.0
RIOK3	-8485.0
TBL3	-8515.0
EXOSC5	-8682.0
NOL12	-8760.0
TSR3	-8968.0

---

REACTOME_HIV_LIFE_CYCLE

REACTOME_HIV_LIFE_CYCLE

	168
set	REACTOME_HIV_LIFE_CYCLE
setSize	145
pANOVA	0.0011
s.dist	0.157
p.adjustANOVA	0.0656

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SEC13	11527
NUP85	11204
TAF12	11000
ELOC	10913
RCC1	10651
CHMP3	10347
TAF9	10000
CCR5	9973
RAE1	9805
RANBP2	9739
UBAP1	9668
CTDP1	9550
RPS27A	9528
POLR2D	9470
PDCD6IP	9381
TBP	9369
TAF11	9352
CCNT2	9318
POLR2H	9192
PSIP1	9118

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SEC13	11527
NUP85	11204
TAF12	11000
ELOC	10913
RCC1	10651
CHMP3	10347
TAF9	10000
CCR5	9973
RAE1	9805
RANBP2	9739
UBAP1	9668
CTDP1	9550
RPS27A	9528
POLR2D	9470
PDCD6IP	9381
TBP	9369
TAF11	9352
CCNT2	9318
POLR2H	9192
PSIP1	9118
XPO1	8796
GTF2H3	8733
POM121C	8691
CXCR4	8636
POLR2C	8572
TAF6	8521
GTF2E1	8409
ELOA2	8183
TCEA1	8153
NEDD4L	8078
FEN1	8054
NUP37	7970
VPS4B	7958
POLR2G	7857
BANF1	7555
TAF4	6968
NCBP2	6845
TAF10	6586
NUP42	6550
SSRP1	6511
GTF2F2	6404
NUP58	6384
RNMT	6346
UBC	6343
XRCC5	6340
VPS4A	6257
ELL	6195
NUP107	6064
VPS37C	5978
RAN	5942
LIG4	5805
GTF2H4	5769
CDK9	5746
POLR2E	5439
TAF2	5347
NDC1	5235
POM121	5192
TAF4B	5147
AAAS	5126
RANGAP1	5116
XRCC6	4968
MVB12B	4953
XRCC4	4622
NUP88	4471
NMT1	4226
TPR	4207
SEH1L	4175
MNAT1	4149
KPNA1	3685
TAF7	3463
CCNT1	3440
NCBP1	3154
GTF2B	2966
CHMP6	2856
NUP62	2832
GTF2E2	2797
SUPT5H	2754
PPIA	2624
NUP205	2621
HMGA1	2615
POLR2F	2100
GTF2H5	2062
RANBP1	1846
TSG101	1834
POLR2L	1774
NUP188	1699
CHMP7	1243
NUP214	1239
GTF2F1	1054
NUP153	1016
NELFE	1008
NUP43	847
CHMP5	822
NUP93	637
VPS37A	560
SUPT4H1	555
TAF3	552
NUP210	420
LIG1	232
POLR2A	197
NUP54	148
SUPT16H	-743
CCNK	-772
VPS37B	-974
TAF15	-1029
CHMP4A	-1080
ELOA	-1162
UBB	-1252
TAF5	-1527
NUP133	-1680
MVB12A	-1772
CHMP2B	-2000
VPS28	-2086
GTF2H1	-2130
CDK7	-2166
POLR2B	-2172
VTA1	-2561
RNGTT	-2718
NUP50	-2854
ERCC2	-3009
CCNH	-3092
POLR2K	-3444
CHMP4B	-3579
NELFA	-3580
GTF2A1	-3596
CHMP2A	-4010
NUP98	-4024
NELFB	-4446
FURIN	-4675
NMT2	-4979
ELOB	-4985
NUP155	-5088
ERCC3	-5552
NELFCD	-5624
NUP160	-5917
NUP35	-6288
POLR2I	-6444
GTF2A2	-7181
CHMP4C	-7232
TAF13	-7341
VPS37D	-7721
CD4	-7809
UBA52	-8028
TAF1L	-8151
POLR2J	-9903

---

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

	594
set	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS
setSize	312
pANOVA	0.00115
s.dist	-0.107
p.adjustANOVA	0.0656

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
HTR1B	-9733
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
DRD4	-9509
CCL3	-9424
TAAR1	-9393
CX3CR1	-9364
CXCL6	-9329
LHB	-9239
NPFFR1	-9194
QRFP	-9192
CCL13	-9113
SUCNR1	-9072

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
HTR1B	-9733
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
DRD4	-9509
CCL3	-9424
TAAR1	-9393
CX3CR1	-9364
CXCL6	-9329
LHB	-9239
NPFFR1	-9194
QRFP	-9192
CCL13	-9113
SUCNR1	-9072
CCR9	-9065
GHSR	-8961
MC2R	-8873
LPAR3	-8870
GPHB5	-8829
AVPR1A	-8819
HTR1F	-8746
LHCGR	-8718
F2RL3	-8689
PTGDR2	-8617
CCKBR	-8605
SSTR1	-8587
PNOC	-8520
BDKRB2	-8462
GPR183	-8429
DRD1	-8427
NTSR2	-8417
PENK	-8412
NPW	-8391
OXER1	-8367
ADRA2C	-8289
TAAR8	-8260
CCL2	-8259
FFAR2	-8246
F2RL2	-7963
CHRM1	-7959
TRH	-7860
PLPPR4	-7769
LPAR2	-7759
KNG1	-7708
CXCL5	-7575
HTR4	-7546
FSHB	-7506
NPSR1	-7436
CXCL2	-7434
HRH3	-7422
EDNRB	-7418
CCR3	-7362
NPB	-7330
SSTR5	-7286
P2RY14	-7240
OPRK1	-7224
MC3R	-7082
ADRB1	-7036
FPR3	-6979
NPY5R	-6836
CXCL3	-6674
GRP	-6577
RXFP2	-6553
PROK2	-6543
AGT	-6496
ADRA2B	-6460
HTR1A	-6448
MC5R	-6393
F2RL1	-6352
S1PR3	-6052
PTGER2	-5957
GPR37	-5949
CCK	-5936
ECE2	-5916
ADRB3	-5794
C5AR1	-5643
CNR1	-5521
DRD5	-5517
OPRL1	-5467
XCL1	-5458
HTR1E	-5408
TAC3	-5384
PMCH	-5352
ACKR3	-5252
MC4R	-5196
S1PR5	-5183
NPY	-4972
RLN2	-4892
PYY	-4866
GALR2	-4819
RGR	-4762
CCKAR	-4576
PF4	-4561
NTS	-4550
CXCL9	-4384
CXCL1	-4382
SSTR2	-4331
TAC1	-4300
TSHR	-4219
NPY1R	-4217
CCR4	-4092
NMBR	-4040
CGA	-3774
PROKR2	-3770
CHRM2	-3732
RRH	-3710
PRLH	-3698
HTR5A	-3625
PDYN	-3573
NPBWR1	-3513
PTAFR	-3454
KISS1	-3425
MC1R	-3415
CCL27	-3389
DRD2	-3335
ADRA1D	-3333
NMUR2	-3305
TBXA2R	-3273
TACR1	-3078
F2	-2987
CCL21	-2911
ADORA2B	-2857
UTS2R	-2818
LTB4R2	-2765
HTR7	-2583
TACR2	-2572
OPN1SW	-2569
CCL1	-2524
TAAR9	-2520
MCHR2	-2459
PRLHR	-2446
SAA1	-2421
CCR10	-2415
CNR2	-2331
GPR35	-2298
GALR1	-2199
RXFP1	-2187
ADORA1	-2159
CMKLR1	-2124
HRH1	-2107
S1PR1	-2049
C3	-2020
PLPPR1	-1914
PTGFR	-1907
GPR65	-1893
ADRA2A	-1881
LPAR5	-1878
GHRL	-1640
EDN1	-1439
MTNR1A	-1391
AVPR1B	-1377
CCL20	-1355
GNRH2	-928
CHRM4	-805
CCL7	-373
CXCL11	-362
PTGDR	-330
ADRA1A	-117
INSL3	-102
F2R	-64
LPAR1	2
FFAR4	43
OXTR	177
HCRTR2	307
ANXA1	317
P2RY1	466
OPN3	612
CCR6	652
CCL17	665
TAAR2	715
HEBP1	734
MLNR	974
CHRM5	1034
CX3CL1	1309
CXCR2	1315
TAAR5	1478
CCRL2	1587
LTB4R	1655
P2RY6	1785
CCL28	1840
GPR4	1912
P2RY2	2030
OPN4	2142
RHO	2339
CXCL12	2377
POMC	2442
SSTR4	2447
TRHR	2481
CXCR5	2559
CXCL16	2585
HTR2B	2657
NPBWR2	2695
MTNR1B	2778
NLN	2828
FSHR	2866
OPRM1	2959
CYSLTR2	2960
EDNRA	3083
OPN5	3091
ADORA3	3157
DRD3	3276
PTGER1	3421
PSAP	3439
NPFFR2	3466
KISS1R	3494
GPBAR1	3771
GPR39	3803
HTR6	3830
NTSR1	3935
EDN2	3955
CCL25	4222
NPY2R	4267
CHRM3	4282
FFAR3	4288
OXGR1	4348
APP	4373
NMU	4395
GAL	4498
GNRH1	4544
ADRB2	4580
APLNR	4597
HCRT	4651
HRH2	4710
P2RY12	4796
LPAR6	4805
QRFPR	4841
CCL19	4861
HCRTR1	5129
TAAR6	5202
C5	5264
GNRHR	5384
CCR2	5405
PPY	5443
EDN3	5710
SSTR3	5832
PLPPR5	5858
ECE1	5927
GPR18	6242
BDKRB1	6284
ADRA1B	6306
S1PR2	6429
GPER1	6584
RLN3	6629
P2RY13	6769
CXCL13	6801
SST	6854
RXFP3	6888
S1PR4	6898
CCR7	6943
AGTR1	7083
CCL23	7130
UTS2B	7264
OPRD1	7367
ACKR2	7532
NMB	7627
C3AR1	7631
PLPPR2	7836
TACR3	7850
RXFP4	7941
GPHA2	8011
PTGER4	8119
NPS	8137
INSL5	8151
PROK1	8216
CCR8	8322
FPR2	8365
KEL	8495
GPR132	8525
CXCR4	8636
UTS2	8723
HCAR1	8744
PTGER3	8962
TSHB	8993
HRH4	9052
ACKR4	9303
HTR1D	9411
CCL22	9532
PROKR1	9925
PLPPR3	9947
CCR5	9973
GALR3	10003
GPR68	10013
NPFF	10161
HTR2A	10279
NMS	10299
GPR31	10372
XCR1	10451
CCL5	10503
GPR37L1	10512
GPR55	10554
CORT	10574
C5AR2	10793
CCR1	10817
GPR17	10822
CXCR6	11068
FFAR1	11077
CXCR1	11116
CCL16	11358
HCAR2	11415
P2RY11	11466
ACKR1	11493
MCHR1	11497
ADORA2A	11523
CCL11	11530
PPBP	11551
PTGIR	11596

---

REACTOME_INFECTIOUS_DISEASE

REACTOME_INFECTIOUS_DISEASE

	974
set	REACTOME_INFECTIOUS_DISEASE
setSize	910
pANOVA	0.00116
s.dist	0.0635
p.adjustANOVA	0.0656

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD3G	11876
IFNA21	11843
CTSG	11741
HBEGF	11563
IFNA16	11557
SEC13	11527
MBL2	11526
RPL7A	11521
GEMIN2	11457
LCK	11410
CD79A	11378
RPS11	11368
MEFV	11352
SFN	11333
NUP85	11204
GNB3	11194
TKFC	11185
SNRPD1	11129
TAF12	11000
RPL10L	10992

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD3G	11876.0
IFNA21	11843.0
CTSG	11741.0
HBEGF	11563.0
IFNA16	11557.0
SEC13	11527.0
MBL2	11526.0
RPL7A	11521.0
GEMIN2	11457.0
LCK	11410.0
CD79A	11378.0
RPS11	11368.0
MEFV	11352.0
SFN	11333.0
NUP85	11204.0
GNB3	11194.0
TKFC	11185.0
SNRPD1	11129.0
TAF12	11000.0
RPL10L	10992.0
RPL17	10955.0
ELOC	10913.0
RPL23A	10886.0
PSMC3	10873.0
RPLP2	10866.0
RPL12	10805.0
RCC1	10651.0
ST3GAL4	10638.0
ENO1	10629.0
GANAB	10488.0
SFPQ	10475.0
RPL4	10452.0
IFNB1	10449.0
TUBB1	10414.0
FXYD1	10410.0
RPL8	10360.0
MGAT5	10356.0
CHMP3	10347.0
TUBA3E	10342.0
CALR	10340.0
RPL14	10335.0
RPS8	10332.0
TOMM70	10308.0
CD8B	10307.0
RPS18	10304.0
PSMB7	10268.0
H3C12	10189.0
IFIH1	10139.0
UBE2N	10132.0
RHBDF2	10114.0
PSMA1	10105.0
RPN1	10042.0
H2AC4	10033.0
STX1B	10018.0
PSTPIP1	10008.0
TLR9	10007.0
TAF9	10000.0
CCR5	9973.0
RPL18	9942.0
RPL34	9922.0
HLA-E	9885.0
TUBA1B	9875.0
RAE1	9805.0
SNRPD2	9791.0
RANBP2	9739.0
H4C8	9710.0
HNRNPA1	9695.0
NMI	9675.0
UBAP1	9668.0
HAVCR1	9657.0
PTGES3	9580.0
SAR1B	9572.0
TBK1	9570.0
MTA3	9565.0
SNRPG	9553.0
CTDP1	9550.0
RPS27A	9528.0
GSDMD	9527.0
H4C9	9476.0
POLR2D	9470.0
SMN1	9435.0
SMN2	9435.0
ISG15	9422.0
RPL22L1	9418.0
PDCD6IP	9381.0
TBP	9369.0
TAF11	9352.0
PCBP2	9322.0
CCNT2	9318.0
H4C3	9304.0
NPM1	9297.0
CRK	9290.0
HLA-G	9276.0
BRD4	9260.0
RPL28	9256.0
IL10	9204.0
SLC25A4	9201.0
POLR2H	9192.0
RPL29	9176.0
STAM	9175.0
EIF2AK2	9161.0
SH3GL3	9151.0
AP1B1	9144.0
PSIP1	9118.0
RPS24	9090.0
NCKIPSD	9056.0
ST3GAL3	9026.0
FXYD6	9014.0
PSMB9	9005.0
RPLP0	8992.0
WASF1	8983.0
JUN	8954.0
GGT5	8942.0
IL6	8933.0
G3BP1	8920.0
ZDHHC2	8897.0
PSMD4	8872.0
ITGA4	8865.0
SRC	8847.0
MAP2K1	8834.0
XPO1	8796.0
RPL41	8792.0
RPL13	8763.0
GRB2	8735.0
GTF2H3	8733.0
PSMD11	8704.0
POM121C	8691.0
FAU	8682.0
RPS13	8647.0
ST3GAL2	8644.0
NLRP3	8642.0
CXCR4	8636.0
NOD1	8634.0
RAB7A	8612.0
ARF1	8590.0
RPS14	8586.0
TBL1XR1	8579.0
POLR2C	8572.0
NFKB1	8542.0
TAF6	8521.0
RUNX1	8520.0
SNRPE	8476.0
ARPC5	8474.0
HLA-B	8428.0
RPL13A	8411.5
GTF2E1	8409.0
ACTR3	8378.0
JAK3	8371.0
GRSF1	8367.0
MBD3	8339.0
DAXX	8330.0
TUBB	8294.0
CD79B	8272.0
HMG20B	8215.0
ELOA2	8183.0
TCEA1	8153.0
RPS19	8143.0
SNF8	8098.0
NEDD4L	8078.0
FEN1	8054.0
GPC5	8034.0
RCOR1	7995.0
SEC24D	7989.0
NUP37	7970.0
RPL22	7968.0
VPS4B	7958.0
POLR2G	7857.0
PHF21A	7793.0
ANO4	7785.0
GNG10	7743.0
RPS7	7735.0
PLCG1	7719.0
SEM1	7709.0
CPSF4	7692.0
AHCYL1	7690.0
C3AR1	7631.0
PSMD12	7629.0
ATP1A1	7590.0
RPS29	7569.0
MAN2A1	7568.0
HGS	7556.0
BANF1	7555.0
B2M	7530.0
H4C11	7529.0
PRKACG	7521.0
CRBN	7512.0
DYNLL1	7506.0
SOS1	7452.0
FKBP4	7430.0
FZD7	7419.0
RPS12	7345.0
DDX20	7269.0
IFNAR1	7267.0
H3C2	7198.0
MYO1C	7186.0
DYNC1H1	7135.0
FXYD7	7132.0
TUBB4B	7088.0
TUBA1A	7010.0
TAF4	6968.0
DPEP2	6912.0
ANO7	6906.0
CORO1A	6872.0
NCBP2	6845.0
PSMC5	6830.0
AP1M1	6779.0
PSMF1	6746.0
PARP10	6726.0
RPL24	6708.0
ST3GAL1	6702.0
GATAD2A	6692.0
SDC3	6689.0
TRIM27	6675.0
ABL1	6647.0
CHD3	6605.0
TAF10	6586.0
SAP18	6582.0
RPS3	6559.0
NUP42	6550.0
SSRP1	6511.0
PSMB1	6496.0
PSMA4	6446.0
SNRPB	6432.0
HSPA1A	6417.0
GTF2F2	6404.0
GPC1	6401.0
NUP58	6384.0
FXYD4	6363.0
MGAT1	6361.0
PSMA2	6356.0
RNMT	6346.0
UBC	6343.0
RPSA	6342.0
XRCC5	6340.0
ZDHHC5	6281.0
VPS4A	6257.0
IL6R	6232.0
DVL2	6224.0
YWHAZ	6221.0
ELL	6195.0
H4C12	6130.0
DPEP3	6085.0
NUP107	6064.0
RPS27	5993.0
VPS37C	5978.0
GSK3A	5975.0
CYBA	5968.0
MET	5960.0
RAN	5942.0
MYH9	5929.0
RPL37A	5921.0
HNRNPK	5904.0
CBL	5869.0
ARID4A	5822.0
LIG4	5805.0
NLRP12	5791.0
WASL	5779.0
GTF2H4	5769.0
PSMD3	5765.0
CDK9	5746.0
ATP1B3	5716.0
PSMA3	5711.0
PSMB8	5690.0
RNF213	5662.0
RPS6	5661.0
VPS25	5621.0
GNG7	5612.0
TUBB8	5589.0
GEMIN4	5570.0
H3C10	5496.0
PARP9	5477.0
ARPC3	5469.0
MGAT4C	5457.0
GEMIN5	5455.0
POLR2E	5439.0
AP1S1	5427.0
CBX1	5417.0
DYNC1LI1	5408.0
VAV2	5352.0
TAF2	5347.0
CD9	5291.0
SUZ12	5273.0
NDC1	5235.0
SERPINE1	5211.0
POM121	5192.0
RPS15A	5190.0
IMPDH1	5177.0
ROCK2	5169.0
TAF4B	5147.0
GGT1	5145.0
AAAS	5126.0
RANGAP1	5116.0
PML	5094.0
ANO5	5084.0
YWHAH	5007.0
DOCK1	4988.0
XRCC6	4968.0
VPS18	4964.0
MVB12B	4953.0
GEMIN7	4938.0
PRKCSH	4899.0
AP1M2	4870.0
PTPN6	4836.0
GNB2	4816.0
VPS39	4682.0
CREBBP	4677.0
APOBEC3G	4666.0
EP300	4662.0
GNAT3	4626.0
XRCC4	4622.0
RPS5	4600.0
BECN1	4573.0
SYT1	4554.0
RPL18A	4496.0
NUP88	4471.0
IFNGR1	4467.0
KPNA2	4429.0
MAP3K7	4396.0
APP	4373.0
PTK2	4367.0
H2AC6	4351.0
IPO5	4337.0
H2BC5	4322.0
GNG13	4294.0
TUFM	4292.0
HDAC3	4286.0
YES1	4285.0
CYFIP2	4278.0
NMT1	4226.0
VAMP2	4225.0
TPR	4207.0
PSME3	4177.0
SEH1L	4175.0
CAV1	4166.0
RPS3A	4153.0
MNAT1	4149.0
MYO10	4135.0
AP1S3	4112.0
IRAK2	4085.0
PRKAR1B	4059.0
EEF1A1	4031.0
PSMB6	3982.0
CANX	3978.0
H3C6	3911.0
ADCY6	3899.0
FXYD2	3884.0
ANO9	3867.0
TYK2	3839.0
PRKACB	3804.0
UVRAG	3755.0
ITCH	3749.0
VAMP1	3735.0
KPNA1	3685.0
SH3GL1	3684.0
SMAD3	3661.0
RPL38	3648.0
ATG14	3631.0
H4C5	3614.0
PAK2	3608.0
COMT	3600.0
GNB1	3572.0
IL17RC	3556.0
BAIAP2	3508.0
GNG12	3495.0
TAF7	3463.0
CHMP1A	3447.0
PRMT1	3445.0
CCNT1	3440.0
ANO6	3403.0
PARP1	3391.0
RPL15	3368.0
ITPR2	3351.0
CTNND1	3335.0
PDCD1	3333.0
H2BC11	3319.0
SAP30L	3313.0
ABI2	3296.0
CTNNB1	3273.0
H4C16	3231.0
VPS45	3227.0
GPC6	3200.0
NCBP1	3154.0
PRKAR1A	3147.0
IFNA6	3146.0
PATJ	3139.0
ATP6V1H	3135.0
GATAD2B	3108.0
RPN2	3073.0
PPIB	3056.0
FUT8	3052.0
VPS11	3047.0
PSMD5	3011.0
GNB5	3005.0
ANTXR1	2992.0
AGRN	2988.0
ADCY9	2982.0
SUGT1	2978.0
H2AC11	2975.0
GTF2B	2966.0
CYSLTR2	2960.0
PSMB10	2924.0
PSMB4	2895.0
MYO5A	2886.0
RPL3L	2883.0
TUBAL3	2860.0
CHMP6	2856.0
NUP62	2832.0
GTF2E2	2797.0
P2RX7	2782.0
SUPT5H	2754.0
AP2A2	2753.0
JAK2	2737.0
IL1B	2714.0
EEF2	2688.0
MAPK3	2655.0
PPIA	2624.0
NUP205	2621.0
HMGA1	2615.0
ZCRB1	2597.0
TAB2	2596.0
RPS9	2500.0
PSMA5	2491.0
PSME1	2473.0
SNRPD3	2471.0
CHD4	2404.0
ROCK1	2365.0
DPEP1	2302.0
RPS2	2297.0
PSMD13	2253.0
AP2S1	2236.0
RPL26L1	2230.0
KPNA5	2205.0
MYO9B	2204.0
DOCK2	2193.0
BCL2L1	2167.0
RPL31	2159.0
H2BC3	2104.0
POLR2F	2100.0
NCOR2	2082.0
NFKB2	2075.0
GTF2H5	2062.0
ADCY2	2059.0
NCKAP1L	2056.0
NOS2	2053.0
DUSP16	2042.0
FNTA	2032.0
VAV1	2015.0
CD163	2008.0
RPL3	1947.0
DAD1	1929.0
SAP30	1920.0
SEC24A	1908.0
RPL36	1899.0
STING1	1894.0
TRAF3	1880.0
AP1G1	1866.0
MAP1LC3B	1847.0
RANBP1	1846.0
TSG101	1834.0
POLR2L	1774.0
H4C4	1764.0
ANTXR2	1749.0
NOD2	1711.0
NUP188	1699.0
REST	1663.0
BLNK	1660.0
ADCY3	1639.0
CLTA	1586.0
ZDHHC20	1576.0
GNAZ	1572.0
GOLGA7	1547.0
RCAN3	1534.0
TRIM25	1464.0
EZH2	1426.0
TUSC3	1387.0
CBLL1	1383.0
PLK2	1372.0
MGAT4A	1323.0
EED	1274.0
H2BC17	1260.0
CHMP7	1243.0
NUP214	1239.0
ABI1	1230.0
RPS27L	1225.0
TXNIP	1203.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
ZDHHC11	1123.0
GNGT1	1092.0
PSMD6	1064.0
NCOR1	1059.0
GTF2F1	1054.0
H2BC12	1033.0
ADCY5	1029.0
NUP153	1016.0
NELFE	1008.0
RPL30	991.0
PSMD9	970.0
RIPK2	959.0
RPL10A	945.0
DDX5	877.0
NUP43	847.0
CHMP5	822.0
MTA2	801.0
SDC4	790.0
RELA	786.0
CLTC	758.0
SEC23A	742.0
RPL35A	733.0
PIK3R4	705.0
NUP93	637.0
WIPF2	599.0
VPS37A	560.0
SUPT4H1	555.0
TAF3	552.0
ST6GALNAC2	536.0
MAVS	522.0
RPL26	511.0
PTPN11	498.0
ITPR1	482.0
NCK1	461.0
IFNA13	436.0
HSP90AA1	431.0
NUP210	420.0
RBBP4	391.0
EPS15	363.0
RPS10	340.0
MOGS	310.0
RNF135	273.0
HSPG2	268.0
LIG1	232.0
STAT1	224.0
PSMD8	214.0
POLR2A	197.0
NUP54	148.0
PSMB5	136.0
ST6GAL1	120.0
RPL39L	118.0
ARPC4	84.0
IL17RA	57.0
H4C2	28.0
SIKE1	-4.0
MYH2	-44.0
GALNT1	-50.0
RIPK3	-105.0
BRK1	-131.0
AP2A1	-132.0
PABPN1	-180.0
RPL27A	-207.0
MTA1	-224.0
VHL	-232.0
MAP2K2	-234.0
RPL23	-246.0
ACTR2	-261.0
RPL35	-273.0
SV2A	-280.0
CDC42	-333.0
PSMA7	-337.0
ENTPD5	-358.0
PSME4	-360.0
PSMC1	-363.0
PARP8	-368.0
KPNA4	-371.0
CHUK	-404.0
H2AC21	-445.0
SEC24C	-518.0
IFNA8	-567.0
PARP4	-572.0
STT3A	-633.0
PALS1	-637.0
IRF7	-638.0
SUPT16H	-743.0
PPIH	-760.0
ATP1A4	-767.0
VPS33B	-771.0
CCNK	-772.0
LARP1	-820.0
GSK3B	-828.0
MAP2K3	-854.0
KDM1A	-912.0
ELMO1	-969.0
VPS37B	-974.0
RPS20	-996.0
KEAP1	-1001.0
CNBP	-1010.0
TAF15	-1029.0
STAT2	-1045.0
LTF	-1055.0
GJA1	-1062.0
CHMP4A	-1080.0
H2AC17	-1098.0
H2AC8	-1100.0
H4C13	-1123.0
H3C3	-1137.0
ELOA	-1162.0
SFTPD	-1179.0
FXYD3	-1207.0
UBB	-1252.0
NFE2L2	-1281.0
MGAT2	-1282.5
RPL36AL	-1282.5
SNAP25	-1294.0
SDC2	-1361.0
HDAC1	-1388.0
PRKAR2A	-1406.0
FGR	-1486.0
PSMA6	-1500.0
TAF5	-1527.0
ZBP1	-1576.0
ADCY1	-1581.0
ANO1	-1605.0
DYNC1I1	-1632.0
NUP133	-1680.0
NOXO1	-1684.0
MVB12A	-1772.0
MAPK14	-1781.0
UBE2I	-1782.0
GNG5	-1791.0
ST6GALNAC3	-1805.0
SUMO1	-1811.0
SEC24B	-1814.0
CD28	-1842.0
H2BC13	-1868.0
IFNGR2	-1903.0
ISCU	-1912.0
TJP1	-1958.0
NR3C1	-1964.0
ATP1A3	-1989.0
CHMP2B	-2000.0
WASF2	-2003.0
SKP1	-2012.0
IFNA1	-2016.0
IL1R1	-2017.0
C3	-2020.0
GNGT2	-2033.0
S1PR1	-2049.0
RPL9	-2057.0
YWHAG	-2065.0
LYN	-2080.0
H2BC1	-2085.0
VPS28	-2086.0
MAP2K6	-2128.0
GTF2H1	-2130.0
TUBB3	-2163.0
SRPK1	-2164.0
CDK7	-2166.0
POLR2B	-2172.0
HCK	-2180.0
ANO3	-2210.0
RPL37	-2213.0
H2BC8	-2215.0
PSMC6	-2235.0
ARPC1B	-2247.0
ANO10	-2327.0
CREB1	-2363.0
HLA-C	-2367.0
WIPF1	-2379.0
TUBA4A	-2383.0
TUBB2A	-2445.0
RPS26	-2447.0
PSMB2	-2499.0
BTRC	-2541.0
YWHAQ	-2543.0
VTA1	-2561.0
STX1A	-2588.0
ANO2	-2643.0
AKT1	-2646.0
RNGTT	-2718.0
CSNK1A1	-2720.0
ATP1B1	-2729.0
FYN	-2742.0
ARID4B	-2768.0
RPS16	-2774.0
PARP6	-2809.0
VPS36	-2851.0
PSMD14	-2853.0
NUP50	-2854.0
ADORA2B	-2857.0
PSME2	-2879.0
CDH1	-2924.0
IMPDH2	-2929.0
ERCC2	-3009.0
VAV3	-3032.0
CCNH	-3092.0
VCP	-3112.0
MAPK1	-3138.0
TXN	-3153.0
GNAI2	-3163.0
DNAJC3	-3168.0
AP2B1	-3170.0
TGFB1	-3196.0
PSMC2	-3243.0
PSMD1	-3280.0
SUDS3	-3295.0
PLCG2	-3296.0
DYNLL2	-3304.0
YWHAB	-3309.0
GNB4	-3317.0
ACTG1	-3326.0
ACTB	-3347.0
H2AC1	-3378.0
POLR2K	-3444.0
NRP1	-3445.0
IKBKB	-3448.0
DYNC1I2	-3484.0
KPNA7	-3523.0
SYT2	-3565.0
CHMP4B	-3579.0
NELFA	-3580.0
GTF2A1	-3596.0
NT5E	-3610.0
UBE2V1	-3648.0
ARPC2	-3716.0
AKT3	-3722.0
WIPF3	-3755.0
DVL3	-3788.0
WASF3	-3796.0
PIK3C3	-3838.0
ZDHHC3	-3875.0
TRAF6	-3915.0
PACS1	-3933.0
IFNA5	-3957.0
IKBKE	-3971.0
RPL6	-3988.0
PKLR	-3998.0
CHMP2A	-4010.0
ENTPD1	-4013.0
CUL5	-4020.0
NUP98	-4024.0
SP1	-4051.0
H2BC15	-4097.0
PARP14	-4121.0
KPNA3	-4150.0
VPS41	-4151.0
PSMB3	-4168.0
NCKAP1	-4182.0
CYFIP1	-4193.0
HMOX1	-4254.0
PYCARD	-4258.0
CALM1	-4297.0
MAN1B1	-4336.0
RPL11	-4362.0
GEMIN6	-4370.0
SIGMAR1	-4381.0
MASP1	-4399.0
RPS15	-4410.0
ITPR3	-4436.0
NELFB	-4446.0
IRF3	-4456.0
EGFR	-4470.0
H4C1	-4509.0
H3C4	-4520.0
FURIN	-4675.0
GNG4	-4676.0
ADCY4	-4707.0
RPL32	-4713.0
SMAD4	-4718.0
RPS25	-4757.0
SRPK2	-4758.0
TUBA4B	-4772.0
PRKACA	-4802.0
P2RX4	-4861.0
HDAC2	-4875.0
H2BC4	-4894.0
PSMD7	-4907.0
KPNB1	-4921.0
NMT2	-4979.0
ELOB	-4985.0
VPS33A	-5018.0
NUP155	-5088.0
RPLP1	-5104.0
H2AC13	-5164.0
NOXA1	-5203.0
MAP2K4	-5206.0
RBX1	-5229.0
ATP1B2	-5260.0
H2AC25	-5275.0
H4C6	-5281.0
ATP1A2	-5302.0
RPL21	-5327.0
H2BC21	-5353.0
DYNC1LI2	-5394.0
ADAM17	-5404.0
AP2M1	-5421.0
FKBP1A	-5443.0
RPL19	-5474.0
TXNRD1	-5479.0
CUL3	-5488.0
PPIG	-5489.0
SV2C	-5494.0
ERCC3	-5552.0
EDEM2	-5579.0
VEGFA	-5600.0
NELFCD	-5624.0
H3C11	-5634.0
ANO8	-5635.0
AKT2	-5661.0
PSMC4	-5662.0
GPC2	-5738.0
H2AC7	-5765.5
H2BC7	-5765.5
ARPC1A	-5814.0
SV2B	-5842.0
H3C8	-5843.0
WNT5A	-5855.0
GNAI1	-5875.0
NUP160	-5917.0
G3BP2	-5938.0
ELMO2	-5982.0
IL17A	-6051.0
NFKBIA	-6060.0
SNRPF	-6098.0
TMPRSS2	-6102.0
DDOST	-6114.0
MGAT4B	-6169.0
RAB5A	-6175.0
RAC1	-6271.0
NUP35	-6288.0
H3C1	-6297.0
GNG8	-6304.0
MAP2K7	-6310.0
GUCY2C	-6369.0
ST6GALNAC4	-6385.0
H2AC16	-6435.0
POLR2I	-6444.0
RB1	-6455.0
GNAI3	-6470.0
HLA-A	-6482.0
ADCY8	-6507.0
GNG2	-6513.0
PRKAR2B	-6534.0
DVL1	-6556.0
HSP90AB1	-6618.0
PDPK1	-6640.0
CRB3	-6643.0
JAK1	-6669.0
TUBA3D	-6718.0
HLA-F	-6755.0
RPL27	-6794.0
ZDHHC8	-6797.0
H2BC9	-6817.5
H3C7	-6817.5
PSMA8	-6922.0
VPS16	-6961.0
CD247	-6962.0
IFNA7	-6973.0
H2AC20	-7047.0
TAB1	-7049.0
FNTB	-7107.0
PSMD2	-7108.0
IL1A	-7131.0
STAM2	-7134.0
H2BC26	-7172.0
GTF2A2	-7181.0
CHMP4C	-7232.0
PSMB11	-7246.0
PARP16	-7248.0
TUBB6	-7272.0
SDC1	-7273.0
IFNAR2	-7277.0
CASP1	-7326.0
BST2	-7328.0
TAF13	-7341.0
ITGB1	-7365.0
RPS28	-7410.0
SH3GL2	-7420.0
IL18	-7429.0
TUBA3C	-7461.0
TUBA1C	-7521.0
H2AC15	-7609.0
MAPK8	-7610.0
SYK	-7713.0
VPS37D	-7721.0
RIPK1	-7765.0
CD4	-7809.0
ADCY7	-7812.0
H2BC6	-7868.0
RPS21	-7890.0
H2BC10	-7996.0
IL17F	-8020.0
UBA52	-8028.0
H2AC12	-8036.0
YWHAE	-8058.0
GNAS	-8089.0
RIGI	-8108.0
TAF1L	-8151.0
BRMS1	-8238.0
TLR1	-8253.0
H2BC14	-8351.0
TRIM4	-8375.0
H2AC18	-8508.5
H2AC19	-8508.5
TUBB4A	-8558.0
GPS2	-8584.0
TLR2	-8600.0
TUBA8	-8659.0
TRIM28	-8736.0
IFNA14	-8752.0
GNG3	-8811.0
FCGR2A	-8842.0
H2AC14	-9055.0
CTSL	-9215.0
MASP2	-9233.0
TUBB2B	-9250.0
CEBPD	-9388.0
GNG11	-9535.0
POLR2J	-9903.0
IFNA2	-9962.0
FCGR3A	-9996.0

---

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

	1364
set	REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize	161
pANOVA	0.00122
s.dist	0.148
p.adjustANOVA	0.0666

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
ELOC	10913
RPL23A	10886
PSMC3	10873
RPLP2	10866
RPL12	10805
MAGOH	10465
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
PSMB7	10268
EIF4G1	10221
PSMA1	10105
RPL18	9942
RPL34	9922

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
ELOC	10913.0
RPL23A	10886.0
PSMC3	10873.0
RPLP2	10866.0
RPL12	10805.0
MAGOH	10465.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
PSMB7	10268.0
EIF4G1	10221.0
PSMA1	10105.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
RPL22L1	9418.0
RBM8A	9403.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
PSMB9	9005.0
RPLP0	8992.0
PSMD4	8872.0
RPL41	8792.0
RPL13	8763.0
PSMD11	8704.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
UPF3A	7901.0
RPS7	7735.0
SEM1	7709.0
PSMD12	7629.0
RPS29	7569.0
CUL2	7403.0
RPS12	7345.0
NCBP2	6845.0
PSMC5	6830.0
PSMF1	6746.0
RPL24	6708.0
RPS3	6559.0
PSMB1	6496.0
PSMA4	6446.0
PSMA2	6356.0
UBC	6343.0
RPSA	6342.0
RPS27	5993.0
RPL37A	5921.0
PSMD3	5765.0
PSMA3	5711.0
PSMB8	5690.0
RPS6	5661.0
EIF4A3	5481.0
RPS15A	5190.0
ETF1	5022.0
ROBO1	4632.0
RPS5	4600.0
RPL18A	4496.0
PSME3	4177.0
RPS3A	4153.0
PSMB6	3982.0
ZSWIM8	3779.0
RPL38	3648.0
RPL15	3368.0
NCBP1	3154.0
PSMD5	3011.0
CASC3	2989.0
PSMB10	2924.0
PSMB4	2895.0
RPL3L	2883.0
RPS9	2500.0
PSMA5	2491.0
PSME1	2473.0
RPS2	2297.0
PSMD13	2253.0
RPL26L1	2230.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
PSMD6	1064.0
RPL30	991.0
PSMD9	970.0
RPL10A	945.0
ROBO2	935.0
RPL35A	733.0
UPF2	706.0
RPL26	511.0
RPS10	340.0
PSMD8	214.0
PSMB5	136.0
RPL39L	118.0
RNPS1	23.0
LDB1	-166.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
PSMA7	-337.0
PSME4	-360.0
PSMC1	-363.0
RPS20	-996.0
UBB	-1252.0
RPL36AL	-1282.5
PSMA6	-1500.0
DAG1	-1639.0
PABPC1	-1756.0
RPL9	-2057.0
RPL37	-2213.0
PSMC6	-2235.0
SLIT2	-2375.0
GSPT1	-2381.0
RPS26	-2447.0
PSMB2	-2499.0
RPS16	-2774.0
PSMD14	-2853.0
PSME2	-2879.0
PSMC2	-3243.0
PSMD1	-3280.0
MAGOHB	-3299.0
HOXA2	-3447.0
ISL1	-3545.0
RPL6	-3988.0
PSMB3	-4168.0
RPL11	-4362.0
RPS15	-4410.0
ROBO3	-4677.0
RPL32	-4713.0
RPS25	-4757.0
LHX9	-4813.0
PSMD7	-4907.0
USP33	-4978.0
ELOB	-4985.0
LHX4	-5057.0
RPLP1	-5104.0
RBX1	-5229.0
SLIT1	-5304.0
RPL21	-5327.0
RPL19	-5474.0
PSMC4	-5662.0
MSI1	-5959.0
LHX2	-6376.0
RPL27	-6794.0
PSMA8	-6922.0
PSMD2	-7108.0
PSMB11	-7246.0
RPS28	-7410.0
RPS21	-7890.0
LHX3	-8013.0
UBA52	-8028.0

---

REACTOME_PROTEIN_LOCALIZATION

REACTOME_PROTEIN_LOCALIZATION

	1461
set	REACTOME_PROTEIN_LOCALIZATION
setSize	153
pANOVA	0.00191
s.dist	0.145
p.adjustANOVA	0.0982

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TIMM23	11393
NUDT7	11001
CHCHD5	10727
TIMM17A	10698
CAT	10384
ACOX2	10328
TOMM70	10308
TIMM13	10272
GRPEL2	10146
COA6	9923
PMPCB	9889
ATP5F1B	9860
PEX19	9663
TYSND1	9613
RPS27A	9528
PEX11B	9500
ACOT4	9359
HSPA9	9277
HSCB	9244
SLC25A4	9201

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TIMM23	11393
NUDT7	11001
CHCHD5	10727
TIMM17A	10698
CAT	10384
ACOX2	10328
TOMM70	10308
TIMM13	10272
GRPEL2	10146
COA6	9923
PMPCB	9889
ATP5F1B	9860
PEX19	9663
TYSND1	9613
RPS27A	9528
PEX11B	9500
ACOT4	9359
HSPA9	9277
HSCB	9244
SLC25A4	9201
TOMM5	9173
ECI2	8591
SAMM50	8383
PEX14	8379
TIMM8B	8342
ABCD2	8297
TOMM40	7967
AMACR	7903
AGPS	7893
PEX10	7800
BAAT	7742
HSD17B4	7652
CRAT	7639
DHRS4	7608
ALDH3A2	7547
PAM16	7488
FXN	7399
ACOT2	7391
PITRM1	7353
ACOX1	7326
VAPA	7224
PXMP2	7193
COX19	7176
PEX12	6918
SERP1	6913
AGXT	6802
PECR	6793
CHCHD4	6778
TOMM22	6733
PEX1	6696
PXMP4	6427
SGTA	6364
UBC	6343
SEC61B	6184
ACO2	6027
UBE2J2	5984
COQ2	5979
DECR2	5807
DAO	5799
TIMM21	5684
BCS1L	5491
IDE	5307
ATP5MC1	5259
MPV17	5246
TIMM9	5185
DDO	4912
LONP2	4783
CS	4490
ATAD1	4481
APP	4373
VAMP2	4225
GNPAT	4040
ACBD5	3734
SLC25A12	3709
UBE2D1	3677
HAO2	3574
PEX7	3486
TOMM7	3453
TOMM20	3437
PEX13	3261
COA4	3027
IDH1	2850
SLC27A2	2825
GET1	2635
CYB5A	2325
HSPD1	2174
CHCHD2	2156
NOS2	2053
MLYCD	1788
GRPEL1	1675
CYC1	1649
VDAC1	1207
ATP5F1A	1173
TIMM10B	1088
HACL1	737
SLC25A17	631
UBE2D2	629
TOMM6	404
PEX6	289
GDAP1	253
ACAA1	160
CHCHD7	90
UBE2D3	81
STX5	-148
BAG6	-168
ACOX3	-334
PEX16	-409
SEC61G	-435
SLC25A13	-464
ABCD3	-891
ZFAND6	-1006
UBB	-1252
NDUFB8	-1302
MTX2	-1308
TIMM22	-1618
PEX2	-1775
CMC2	-1984
GET4	-2139
PIPOX	-2157
CHCHD3	-2390
STX1A	-2588
PHYH	-3056
ACOT8	-3079
SCP2	-3539
OTOF	-3594
COX17	-4103
CROT	-4135
HMOX1	-4254
HMGCL	-4259
GET3	-4453
TIMM44	-4679
PMPCA	-5105
EPHX2	-5251
GFER	-5273
DNAJC19	-5509
EHHADH	-5544
PEX26	-5551
FIS1	-5941
ECH1	-5962
HAO1	-6110
TIMM10	-6118
TIMM50	-6518
NUDT19	-6690
PEX5	-7105
CHCHD10	-7149
PRNP	-7262
UBA52	-8028
CAMLG	-8529
GSTK1	-8707
PEX3	-8711
MTX1	-8786
PAOX	-8909
LDHD	-9835

---

REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS

REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS

	1055
set	REACTOME_METAL_SEQUESTRATION_BY_ANTIMICROBIAL_PROTEINS
setSize	6
pANOVA	0.00191
s.dist	0.732
p.adjustANOVA	0.0982

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCN2	11945
S100A8	11918
S100A9	11541
S100A7	11481
S100A7A	8292
LTF	-1055

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCN2	11945
S100A8	11918
S100A9	11541
S100A7	11481
S100A7A	8292
LTF	-1055

---

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

	1150
set	REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize	53
pANOVA	0.00227
s.dist	0.242
p.adjustANOVA	0.113

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS11	11368
EIF3K	10623
RPS8	10332
RPS18	10304
EIF4G1	10221
EIF4A1	9908
RPS27A	9528
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
EIF4B	8573
RPS19	8143
RPS7	7735
RPS29	7569
EIF3D	7437
RPS12	7345
EIF4EBP1	7169
RPS3	6559
RPSA	6342

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS11	11368
EIF3K	10623
RPS8	10332
RPS18	10304
EIF4G1	10221
EIF4A1	9908
RPS27A	9528
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
EIF4B	8573
RPS19	8143
RPS7	7735
RPS29	7569
EIF3D	7437
RPS12	7345
EIF4EBP1	7169
RPS3	6559
RPSA	6342
EIF4A2	6253
RPS27	5993
EIF2S1	5780
RPS6	5661
EIF3E	5451
RPS15A	5190
EIF3H	4784
RPS5	4600
RPS3A	4153
EIF3M	3664
EIF3A	2776
RPS9	2500
EIF3L	2479
RPS2	2297
EIF4E	1903
RPS27L	1225
RPS23	1164
EIF4H	1066
EIF3B	636
RPS10	340
RPS20	-996
EIF3G	-1279
PABPC1	-1756
EIF3I	-1885
RPS26	-2447
RPS16	-2774
EIF3F	-4023
RPS15	-4410
EIF3J	-4610
RPS25	-4757
EIF2S2	-5277
RPS28	-7410
RPS21	-7890

---

REACTOME_AMINE_LIGAND_BINDING_RECEPTORS

REACTOME_AMINE_LIGAND_BINDING_RECEPTORS

	602
set	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS
setSize	40
pANOVA	0.00326
s.dist	-0.269
p.adjustANOVA	0.155

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HTR1B	-9733
DRD4	-9509
TAAR1	-9393
HTR1F	-8746
DRD1	-8427
ADRA2C	-8289
TAAR8	-8260
CHRM1	-7959
HTR4	-7546
HRH3	-7422
ADRB1	-7036
ADRA2B	-6460
HTR1A	-6448
ADRB3	-5794
DRD5	-5517
HTR1E	-5408
CHRM2	-3732
HTR5A	-3625
DRD2	-3335
ADRA1D	-3333

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HTR1B	-9733
DRD4	-9509
TAAR1	-9393
HTR1F	-8746
DRD1	-8427
ADRA2C	-8289
TAAR8	-8260
CHRM1	-7959
HTR4	-7546
HRH3	-7422
ADRB1	-7036
ADRA2B	-6460
HTR1A	-6448
ADRB3	-5794
DRD5	-5517
HTR1E	-5408
CHRM2	-3732
HTR5A	-3625
DRD2	-3335
ADRA1D	-3333
HTR7	-2583
TAAR9	-2520
HRH1	-2107
ADRA2A	-1881
CHRM4	-805
ADRA1A	-117
TAAR2	715
CHRM5	1034
TAAR5	1478
HTR2B	2657
DRD3	3276
HTR6	3830
CHRM3	4282
ADRB2	4580
HRH2	4710
TAAR6	5202
ADRA1B	6306
HRH4	9052
HTR1D	9411
HTR2A	10279

---

REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM

	484
set	REACTOME_SELENOAMINO_ACID_METABOLISM
setSize	108
pANOVA	0.0033
s.dist	0.164
p.adjustANOVA	0.155

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
RPL23A	10886
NNMT	10882
RPLP2	10866
RPL12	10805
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
MAT1A	9960
RPL18	9942
RPL34	9922
RPS27A	9528
RPL22L1	9418
RPL28	9256
RPL29	9176

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
RPL23A	10886.0
NNMT	10882.0
RPLP2	10866.0
RPL12	10805.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
MAT1A	9960.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
RPL22L1	9418.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
RPLP0	8992.0
RPL41	8792.0
RPL13	8763.0
FAU	8682.0
RPS13	8647.0
RPS14	8586.0
RPL13A	8411.5
RPS19	8143.0
RPL22	7968.0
RPS7	7735.0
RPS29	7569.0
RPS12	7345.0
RPL24	6708.0
RPS3	6559.0
RPSA	6342.0
RPS27	5993.0
RPL37A	5921.0
AIMP1	5766.0
RPS6	5661.0
RPS15A	5190.0
DARS1	4754.0
LARS1	4609.0
RPS5	4600.0
RPL18A	4496.0
AHCY	4254.0
RPS3A	4153.0
INMT	4020.0
EPRS1	3948.0
RPL38	3648.0
RPL15	3368.0
RARS1	3150.0
RPL3L	2883.0
SEPSECS	2869.0
RPS9	2500.0
RPS2	2297.0
RPL26L1	2230.0
RPL31	2159.0
HNMT	2130.0
RPL3	1947.0
RPL36	1899.0
PSTK	1515.0
MARS1	1379.0
KARS1	1299.0
RPS27L	1225.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
RPL30	991.0
RPL10A	945.0
RPL35A	733.0
AIMP2	550.0
RPL26	511.0
RPS10	340.0
RPL39L	118.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
IARS1	-906.0
RPS20	-996.0
RPL36AL	-1282.5
CTH	-1284.0
RPL9	-2057.0
RPL37	-2213.0
EEFSEC	-2328.0
RPS26	-2447.0
RPS16	-2774.0
RPL6	-3988.0
RPL11	-4362.0
RPS15	-4410.0
SCLY	-4682.0
RPL32	-4713.0
RPS25	-4757.0
EEF1E1	-4963.0
RPLP1	-5104.0
RPL21	-5327.0
RPL19	-5474.0
TXNRD1	-5479.0
SECISBP2	-6022.0
SEPHS2	-6463.0
RPL27	-6794.0
PAPSS2	-7288.0
RPS28	-7410.0
GSR	-7489.0
RPS21	-7890.0
UBA52	-8028.0
PAPSS1	-8060.0
GNMT	-8820.0

---

REACTOME_DRUG_ADME

REACTOME_DRUG_ADME

	1593
set	REACTOME_DRUG_ADME
setSize	103
pANOVA	0.00343
s.dist	0.167
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
UGT2B7	11819
GSTA1	11740
GGT6	11487
ACSM2B	11245
ACSM4	10762
ACSM2A	10567
ABCC3	10313
CYP2C19	10225
SLCO1A2	10016
SLC29A3	9883
UGT2A1	9703
HSD11B1	9649
UGT2B15	9450
UGT2B4	9241
CES2	9178
GGT5	8942
GLYATL1	8784
ABCG2	8619
SLCO1B1	8372
NUDT15	8175

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
UGT2B7	11819
GSTA1	11740
GGT6	11487
ACSM2B	11245
ACSM4	10762
ACSM2A	10567
ABCC3	10313
CYP2C19	10225
SLCO1A2	10016
SLC29A3	9883
UGT2A1	9703
HSD11B1	9649
UGT2B15	9450
UGT2B4	9241
CES2	9178
GGT5	8942
GLYATL1	8784
ABCG2	8619
SLCO1B1	8372
NUDT15	8175
UGT1A5	8133
UGT2A3	7910
CYP2C8	7829
UGT1A1	7778
CES1	7727
UGT1A3	7679
GLYAT	7641
UGT2B11	7510
UGT1A4	7508
CNDP2	7249
ABCC2	7076
UGT3A1	6728
PCK1	6611
ABCC1	6525
SLC29A1	6173
GMPS	5952
SULT1A1	5940
SLC28A3	5810
UGT1A6	5809
GSTP1	5796
ABCC5	5751
UGT2B17	5633
VAV2	5352
NME1	5310
CYP3A4	5241
IMPDH1	5177
GGT1	5145
BSG	4975
BCHE	4387
NAT2	4379
ALB	4349
ABCC4	4284
SLC29A2	3921
CYP2D6	3850
UGT1A9	3580
UGT1A7	3316
GLYATL2	3074
SLC22A1	2405
UGT2A2	2278
TPMT	2033
VAV1	2015
ITPA	1921
GLYATL3	1870
ADK	1758
UGT1A10	1717
SLCO2B1	1434
UGT3A2	1297
UGT1A8	1210
XDH	995
SLC16A1	-6
SULT1C4	-239
ACY1	-755
NME2	-765
SULT2A1	-1546
HSD11B2	-1920
PON1	-1938
SLC28A2	-2439
PON3	-2908
IMPDH2	-2929
PNP	-2960
VAV3	-3032
GUK1	-3037
ABCB1	-3050
NAT1	-3234
ADH1A	-3671
SLC22A2	-4488
SERPINA6	-4540
SULT1E1	-4593
SLC22A8	-4672
ADA	-5154
NT5C2	-5313
AKR1C1	-5490
CYP2C9	-5808
SLC22A7	-6069
RAC1	-6271
SLC22A3	-6368
SLCO1B3	-6539
GSTM1	-6624
GGT7	-7141
ADAL	-7771
CYP2E1	-8019
ACSM5	-8537
GSTA2	-9914

---

REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS

	160
set	REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS
setSize	18
pANOVA	0.00354
s.dist	0.397
p.adjustANOVA	0.157

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SLC10A2	11594
SLC10A1	11004
SLC51B	10952
ABCC3	10313
SLCO1A2	10016
SLCO1B1	8372
BAAT	7742
FABP6	7009
NCOA2	6763
NR1H4	6014
STARD5	5454
SLC51A	5154
RXRA	5055
ALB	4349
ABCB11	3739
NCOA1	-1968
SLCO1B3	-6539
SLC27A5	-8936

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SLC10A2	11594
SLC10A1	11004
SLC51B	10952
ABCC3	10313
SLCO1A2	10016
SLCO1B1	8372
BAAT	7742
FABP6	7009
NCOA2	6763
NR1H4	6014
STARD5	5454
SLC51A	5154
RXRA	5055
ALB	4349
ABCB11	3739
NCOA1	-1968
SLCO1B3	-6539
SLC27A5	-8936

---

REACTOME_POTASSIUM_CHANNELS

REACTOME_POTASSIUM_CHANNELS

	83
set	REACTOME_POTASSIUM_CHANNELS
setSize	102
pANOVA	0.00419
s.dist	-0.164
p.adjustANOVA	0.175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GNG11	-9535
KCNK7	-9376
KCNJ8	-9359
KCNK6	-9084
KCNK1	-9004
KCNN4	-8857
GNG3	-8811
KCNA4	-8772
KCNJ3	-8570
KCNN1	-8398
KCNA3	-8188
KCNJ14	-7832
KCNG1	-7703
KCNN2	-7629
KCNJ2	-7357
KCNH6	-7020
KCNK10	-6939
KCNS1	-6743
KCNJ10	-6687
GNG2	-6513

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GNG11	-9535
KCNK7	-9376
KCNJ8	-9359
KCNK6	-9084
KCNK1	-9004
KCNN4	-8857
GNG3	-8811
KCNA4	-8772
KCNJ3	-8570
KCNN1	-8398
KCNA3	-8188
KCNJ14	-7832
KCNG1	-7703
KCNN2	-7629
KCNJ2	-7357
KCNH6	-7020
KCNK10	-6939
KCNS1	-6743
KCNJ10	-6687
GNG2	-6513
KCNS3	-6452
GNG8	-6304
KCND2	-6194
KCNA1	-5834
KCNV1	-5237
KCNA5	-5236
GNG4	-4676
KCNQ2	-4629
KCNJ6	-4563
KCNC1	-4353
KCNH2	-4266
HCN3	-3892
KCNS2	-3882
KCNG3	-3553
KCNA7	-3469
KCNK4	-3465
GNB4	-3317
KCNG4	-3089
KCNMA1	-2939
KCNK9	-2751
KCNV2	-2736
KCNMB1	-2733
KCNK17	-2724
GNGT2	-2033
KCNAB3	-1852
GNG5	-1791
KCNJ12	-1652
KCNAB1	-1582
KCNN3	-1236
KCNB2	-918
HCN2	-650
KCNF1	-588
KCNQ3	-290
KCNG2	-197
KCND3	-127
KCNB1	20
KCNH1	42
KCNH4	46
KCNMB2	144
KCNJ15	216
KCNH5	595
KCNJ4	654
ABCC8	855
HCN4	929
KCNQ4	960
KCNK16	1044
GNGT1	1092
KCNJ1	1130
KCNQ1	1631
KCNC3	1982
KCNK3	2012
KCNK2	2311
KCNQ5	2346
KCNJ9	2602
GNB5	3005
KCNK13	3207
KCNA6	3304
GNG12	3495
GNB1	3572
GABBR1	3717
ABCC9	3918
KCNK18	4078
KCNH3	4196
GNG13	4294
KCNJ5	4346
KCNA10	4563
GNB2	4816
KCNH7	5072
GNG7	5612
KCNC4	5884
GABBR2	5898
KCNJ11	6240
KCNAB2	7127
KCNJ16	7664
KCNH8	7693
GNG10	7743
HCN1	8669
KCNC2	8799
KCNMB4	9402
KCNMB3	9715
KCNA2	9719
GNB3	11194

---

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

	1591
set	REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize	33
pANOVA	0.00424
s.dist	0.288
p.adjustANOVA	0.175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPS11	11368
RPS8	10332
RPS18	10304
HNRNPA1	9695
RPS27A	9528
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
RPS19	8143
RPS7	7735
RPS29	7569
RPS12	7345
RPS3	6559
RPSA	6342
RPS27	5993
RPS6	5661
RPS15A	5190
RPS5	4600
RPS3A	4153

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPS11	11368
RPS8	10332
RPS18	10304
HNRNPA1	9695
RPS27A	9528
RPS24	9090
FAU	8682
RPS13	8647
RPS14	8586
RPS19	8143
RPS7	7735
RPS29	7569
RPS12	7345
RPS3	6559
RPSA	6342
RPS27	5993
RPS6	5661
RPS15A	5190
RPS5	4600
RPS3A	4153
EEF1A1	4031
RPS9	2500
RPS2	2297
RPS27L	1225
RPS23	1164
RPS10	340
RPS20	-996
RPS26	-2447
RPS16	-2774
RPS15	-4410
RPS25	-4757
RPS28	-7410
RPS21	-7890

---

REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

	33
set	REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES
setSize	255
pANOVA	0.00436
s.dist	-0.104
p.adjustANOVA	0.175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GNG11	-9535
TUBB2B	-9250
CHRNA5	-9066
HRAS	-8845
GABRG2	-8844
GNG3	-8811
TUBA8	-8659
UNC13B	-8621
KCNJ3	-8570
TUBB4A	-8558
APBA1	-8510
CACNG8	-8494
SLC32A1	-8484
GRIN1	-8278
AKAP5	-8277
CHRNA4	-8204
PPM1E	-8103
NEFL	-7986
SLC18A3	-7955
SLC5A7	-7824

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GNG11	-9535
TUBB2B	-9250
CHRNA5	-9066
HRAS	-8845
GABRG2	-8844
GNG3	-8811
TUBA8	-8659
UNC13B	-8621
KCNJ3	-8570
TUBB4A	-8558
APBA1	-8510
CACNG8	-8494
SLC32A1	-8484
GRIN1	-8278
AKAP5	-8277
CHRNA4	-8204
PPM1E	-8103
NEFL	-7986
SLC18A3	-7955
SLC5A7	-7824
ADCY7	-7812
CACNG3	-7798
GABRR1	-7725
GABRA2	-7660
TUBA1C	-7521
TUBA3C	-7461
KCNJ2	-7357
GRIN2D	-7294
TUBB6	-7272
CACNA1B	-6972
SLC6A12	-6857
CHRND	-6855
TUBA3D	-6718
KCNJ10	-6687
PDPK1	-6640
SLC6A4	-6535
PRKAR2B	-6534
GNG2	-6513
ADCY8	-6507
GNAI3	-6470
CACNG4	-6374
SLC17A7	-6353
GNG8	-6304
RAC1	-6271
SLC18A2	-6077
GABRB1	-5944
GLRB	-5934
LRTOMT	-5923
MAPT	-5909
GNAI1	-5875
PRKAA2	-5787
GRIK4	-5622
ACHE	-5580
CHAT	-5523
LIN7B	-5430
AP2M1	-5421
CACNA2D2	-5330
GRIN3B	-5079
HTR3B	-4991
PRKACA	-4802
TUBA4B	-4772
ADCY4	-4707
SLC6A13	-4687
GNG4	-4676
PRKCG	-4651
KCNJ6	-4563
ACTN2	-4500
NAAA	-4494
SLC22A2	-4488
CAMK2B	-4476
GRIN2C	-4406
NCALD	-4317
PRKAG3	-4310
CALM1	-4297
SLC6A3	-4240
ARL6IP5	-4117
SLC6A1	-4076
PLCB2	-4046
CHRNE	-3910
SLC1A1	-3872
KRAS	-3860
MDM2	-3839
GLRA1	-3773
GRIK3	-3674
GABRA5	-3621
CACNA1E	-3611
GRIN2A	-3418
GAD1	-3407
GNB4	-3317
AP2B1	-3170
GNAI2	-3163
MAPK1	-3138
LIN7A	-2980
CACNB4	-2896
CHRNB3	-2865
CHRNB2	-2760
STX1A	-2588
DLG4	-2534
KIF17	-2484
NPTN	-2464
TUBB2A	-2445
PRKAG1	-2442
CHRNA3	-2436
MYO6	-2416
CHRNA2	-2400
TUBA4A	-2383
CREB1	-2363
TUBB3	-2163
GABRR2	-2104
GNGT2	-2033
GRIA2	-1951
CPLX1	-1949
GNG5	-1791
SLC1A3	-1739
CAMKK1	-1730
KCNJ12	-1652
ADCY1	-1581
RASGRF1	-1555
PPFIA2	-1450
PRKAR2A	-1406
SNAP25	-1294
GNAL	-1025
GRIA4	-850
GAD2	-826
GABRA1	-802
GABRG3	-688
GRIP1	-616
CACNB3	-604
GABRB2	-329
RPS6KA2	-209
CACNB2	-205
AP2A1	-132
CACNG2	-111
CAMK1	146
KCNJ15	216
RIMS1	308
RPS6KA1	327
SLC1A6	338
RAB3A	434
SLC38A2	639
KCNJ4	654
NBEA	699
PPFIA3	884
SYN2	890
PPM1F	948
ADCY5	1029
GNGT1	1092
GABRA4	1385
NRGN	1391
DNAJC5	1418
CHRNB4	1483
GLS	1511
HTR3A	1618
ADCY3	1639
GRIK5	1818
ADCY2	2059
EPB41L1	2115
PPFIA1	2165
AP2S1	2236
SLC22A1	2405
PRKCB	2423
NRG1	2502
ARHGEF7	2582
KCNJ9	2602
PLCB3	2614
MAPK3	2655
ERBB4	2674
AP2A2	2753
CAMK2A	2854
TUBAL3	2860
GRIK1	2955
ADCY9	2982
GNB5	3005
SLC1A2	3019
GRIN3A	3049
PRKAR1A	3147
RASGRF2	3194
PPFIA4	3206
GRIN2B	3346
GNG12	3495
GNB1	3572
COMT	3600
GIT1	3621
HTR3D	3644
SLC1A7	3678
CACNA1A	3688
HTR3E	3704
GABBR1	3717
PRKACB	3804
CAMK4	3824
DLG1	3825
ADCY6	3899
GRIP2	4022
PRKAR1B	4059
PRKAB2	4095
HSPA8	4148
VAMP2	4225
GNG13	4294
KCNJ5	4346
BCHE	4387
KPNA2	4429
GABRB3	4542
SYT1	4554
GNAT3	4626
GRIK2	4627
GNB2	4816
SLC6A11	4923
PRKCA	5109
CAMK2D	5270
DLG2	5367
TUBB8	5589
PLCB1	5601
GNG7	5612
CAMKK2	5626
STXBP1	5733
GABBR2	5898
LRRC7	6164
HTR3C	6451
NSF	6538
TUBA1A	7010
TUBB4B	7088
PRKAG2	7192
GLRA3	7247
PRKACG	7521
KCNJ16	7664
GNG10	7743
CHRNA1	7767
PRKAB1	7861
ALDH2	7973
ALDH5A1	8087
CHRNA7	8089
PRKAA1	8210
TSPOAP1	8398
CACNA2D3	8437
SYN3	8554
GLS2	8627
GLUL	8790
PICK1	8798
SRC	8847
CHRNA6	8859
GABRR3	8965
LIN7C	9010
SLC38A1	9095
GABRA6	9433
CAMK2G	9674
GRIA1	9726
ABAT	9858
CHRNA9	9864
TUBA1B	9875
CHRNG	10038
CACNB1	10159
NRAS	10256
TUBA3E	10342
TUBB1	10414
GNB3	11194

---

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS

	605
set	REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize	206
pANOVA	0.00438
s.dist	0.115
p.adjustANOVA	0.175

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RPL7A	11521
RPS11	11368
RPL10L	10992
RPL17	10955
ELOC	10913
RPL23A	10886
PSMC3	10873
RPLP2	10866
RPL12	10805
MAGOH	10465
RPL4	10452
RPL8	10360
RPL14	10335
RPS8	10332
RPS18	10304
PSMB7	10268
EIF4G1	10221
PSMA1	10105
RPL18	9942
RPL34	9922

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RPL7A	11521.0
RPS11	11368.0
RPL10L	10992.0
RPL17	10955.0
ELOC	10913.0
RPL23A	10886.0
PSMC3	10873.0
RPLP2	10866.0
RPL12	10805.0
MAGOH	10465.0
RPL4	10452.0
RPL8	10360.0
RPL14	10335.0
RPS8	10332.0
RPS18	10304.0
PSMB7	10268.0
EIF4G1	10221.0
PSMA1	10105.0
RPL18	9942.0
RPL34	9922.0
RPS27A	9528.0
RPL22L1	9418.0
RBM8A	9403.0
RPL28	9256.0
RPL29	9176.0
RPS24	9090.0
PSMB9	9005.0
RPLP0	8992.0
PSMD4	8872.0
SRC	8847.0
RPL41	8792.0
RPL13	8763.0
PSMD11	8704.0
VASP	8688.0
FAU	8682.0
RPS13	8647.0
CXCR4	8636.0
RPS14	8586.0
RPL13A	8411.5
NTN1	8301.0
RPS19	8143.0
RPL22	7968.0
UPF3A	7901.0
RPS7	7735.0
SEM1	7709.0
PSMD12	7629.0
RPS29	7569.0
PRKACG	7521.0
SOS1	7452.0
ABL2	7449.0
CUL2	7403.0
RPS12	7345.0
NCBP2	6845.0
PSMC5	6830.0
PSMF1	6746.0
RPL24	6708.0
ABL1	6647.0
RPS3	6559.0
PSMB1	6496.0
PSMA4	6446.0
GPC1	6401.0
PSMA2	6356.0
UBC	6343.0
RPSA	6342.0
RPS27	5993.0
RPL37A	5921.0
PSMD3	5765.0
PSMA3	5711.0
PSMB8	5690.0
RPS6	5661.0
PPP3CB	5613.0
EIF4A3	5481.0
RPS15A	5190.0
PRKCA	5109.0
ETF1	5022.0
SRGAP3	4886.0
ROBO1	4632.0
RPS5	4600.0
RPL18A	4496.0
SLIT3	4272.0
PSME3	4177.0
RPS3A	4153.0
PSMB6	3982.0
PRKACB	3804.0
PFN1	3790.0
ZSWIM8	3779.0
RPL38	3648.0
PAK2	3608.0
RPL15	3368.0
NCBP1	3154.0
PSMD5	3011.0
CASC3	2989.0
EVL	2951.0
PSMB10	2924.0
PAK5	2921.0
PSMB4	2895.0
RPL3L	2883.0
FLRT3	2728.0
RPS9	2500.0
PSMA5	2491.0
PSME1	2473.0
CXCL12	2377.0
RPS2	2297.0
PSMD13	2253.0
RPL26L1	2230.0
CAP1	2222.0
MYO9B	2204.0
RPL31	2159.0
RPL3	1947.0
RPL36	1899.0
ENAH	1430.0
RHOA	1411.0
RPS27L	1225.0
CLASP1	1211.0
RPS23	1164.0
RPL7	1159.0
RPL5	1132.0
PSMD6	1064.0
RPL30	991.0
PSMD9	970.0
RPL10A	945.0
ROBO2	935.0
RPL35A	733.0
UPF2	706.0
RPL26	511.0
NCK1	461.0
RPS10	340.0
NCK2	225.0
PSMD8	214.0
PSMB5	136.0
RPL39L	118.0
RNPS1	23.0
LDB1	-166.0
RPL27A	-207.0
RPL23	-246.0
RPL35	-273.0
CDC42	-333.0
PSMA7	-337.0
PSME4	-360.0
PSMC1	-363.0
RPS20	-996.0
UBB	-1252.0
RPL36AL	-1282.5
PRKAR2A	-1406.0
PSMA6	-1500.0
SRGAP1	-1562.0
DAG1	-1639.0
PABPC1	-1756.0
ARHGAP39	-2040.0
RPL9	-2057.0
PAK4	-2196.0
RPL37	-2213.0
PSMC6	-2235.0
SLIT2	-2375.0
GSPT1	-2381.0
RPS26	-2447.0
PSMB2	-2499.0
RPS16	-2774.0
PSMD14	-2853.0
PSME2	-2879.0
PSMC2	-3243.0
PSMD1	-3280.0
MAGOHB	-3299.0
PAK1	-3300.0
NELL2	-3372.0
NRP1	-3445.0
HOXA2	-3447.0
ISL1	-3545.0
PFN2	-3810.0
RPL6	-3988.0
PAK6	-4099.0
PSMB3	-4168.0
RPL11	-4362.0
RPS15	-4410.0
ROBO3	-4677.0
RPL32	-4713.0
RPS25	-4757.0
PRKACA	-4802.0
LHX9	-4813.0
PSMD7	-4907.0
USP33	-4978.0
ELOB	-4985.0
LHX4	-5057.0
RPLP1	-5104.0
DCC	-5217.0
SRGAP2	-5225.0
RBX1	-5229.0
SLIT1	-5304.0
CLASP2	-5305.0
RPL21	-5327.0
RPL19	-5474.0
PSMC4	-5662.0
MSI1	-5959.0
RAC1	-6271.0
LHX2	-6376.0
RPL27	-6794.0
PSMA8	-6922.0
PSMD2	-7108.0
PSMB11	-7246.0
RPS28	-7410.0
RPS21	-7890.0
LHX3	-8013.0
UBA52	-8028.0
AKAP5	-8277.0
SOS2	-8881.0
CAP2	-9052.0

---

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS

	601
set	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS
setSize	188
pANOVA	0.00462
s.dist	-0.12
p.adjustANOVA	0.181

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
CCL3	-9424
CX3CR1	-9364
CXCL6	-9329
NPFFR1	-9194
QRFP	-9192
CCL13	-9113
CCR9	-9065
GHSR	-8961
MC2R	-8873
AVPR1A	-8819
F2RL3	-8689

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CCL4	-9937
OXT	-9780
CXCL10	-9769
NMUR1	-9768
AVP	-9755
CXCL8	-9672
XCL2	-9666
FPR1	-9651
MLN	-9565
CCL3	-9424
CX3CR1	-9364
CXCL6	-9329
NPFFR1	-9194
QRFP	-9192
CCL13	-9113
CCR9	-9065
GHSR	-8961
MC2R	-8873
AVPR1A	-8819
F2RL3	-8689
CCKBR	-8605
SSTR1	-8587
PNOC	-8520
BDKRB2	-8462
NTSR2	-8417
PENK	-8412
NPW	-8391
CCL2	-8259
F2RL2	-7963
TRH	-7860
KNG1	-7708
CXCL5	-7575
NPSR1	-7436
CXCL2	-7434
EDNRB	-7418
CCR3	-7362
NPB	-7330
SSTR5	-7286
OPRK1	-7224
MC3R	-7082
FPR3	-6979
NPY5R	-6836
CXCL3	-6674
GRP	-6577
RXFP2	-6553
PROK2	-6543
AGT	-6496
MC5R	-6393
F2RL1	-6352
GPR37	-5949
CCK	-5936
ECE2	-5916
C5AR1	-5643
OPRL1	-5467
XCL1	-5458
TAC3	-5384
PMCH	-5352
ACKR3	-5252
MC4R	-5196
NPY	-4972
RLN2	-4892
PYY	-4866
GALR2	-4819
CCKAR	-4576
PF4	-4561
NTS	-4550
CXCL9	-4384
CXCL1	-4382
SSTR2	-4331
TAC1	-4300
NPY1R	-4217
CCR4	-4092
NMBR	-4040
PROKR2	-3770
PRLH	-3698
PDYN	-3573
NPBWR1	-3513
KISS1	-3425
MC1R	-3415
CCL27	-3389
NMUR2	-3305
TACR1	-3078
F2	-2987
CCL21	-2911
UTS2R	-2818
TACR2	-2572
CCL1	-2524
MCHR2	-2459
PRLHR	-2446
SAA1	-2421
CCR10	-2415
GALR1	-2199
RXFP1	-2187
C3	-2020
GHRL	-1640
EDN1	-1439
AVPR1B	-1377
CCL20	-1355
CCL7	-373
CXCL11	-362
INSL3	-102
F2R	-64
OXTR	177
HCRTR2	307
ANXA1	317
CCR6	652
CCL17	665
HEBP1	734
MLNR	974
CX3CL1	1309
CXCR2	1315
CCRL2	1587
CCL28	1840
CXCL12	2377
POMC	2442
SSTR4	2447
TRHR	2481
CXCR5	2559
CXCL16	2585
NPBWR2	2695
NLN	2828
OPRM1	2959
EDNRA	3083
PSAP	3439
NPFFR2	3466
KISS1R	3494
NTSR1	3935
EDN2	3955
CCL25	4222
NPY2R	4267
APP	4373
NMU	4395
GAL	4498
APLNR	4597
HCRT	4651
QRFPR	4841
CCL19	4861
HCRTR1	5129
C5	5264
CCR2	5405
PPY	5443
EDN3	5710
SSTR3	5832
ECE1	5927
BDKRB1	6284
GPER1	6584
RLN3	6629
CXCL13	6801
SST	6854
RXFP3	6888
CCR7	6943
AGTR1	7083
CCL23	7130
UTS2B	7264
OPRD1	7367
ACKR2	7532
NMB	7627
C3AR1	7631
TACR3	7850
RXFP4	7941
NPS	8137
INSL5	8151
PROK1	8216
CCR8	8322
FPR2	8365
KEL	8495
CXCR4	8636
UTS2	8723
ACKR4	9303
CCL22	9532
PROKR1	9925
CCR5	9973
GALR3	10003
NPFF	10161
NMS	10299
XCR1	10451
CCL5	10503
GPR37L1	10512
CORT	10574
C5AR2	10793
CCR1	10817
CXCR6	11068
CXCR1	11116
CCL16	11358
ACKR1	11493
MCHR1	11497
CCL11	11530
PPBP	11551

---

REACTOME_DNA_METHYLATION

REACTOME_DNA_METHYLATION

	858
set	REACTOME_DNA_METHYLATION
setSize	58
pANOVA	0.00494
s.dist	-0.213
p.adjustANOVA	0.189

Top enriched genes

Top 20 genes

GeneID	Gene Rank
H2AC14	-9055.0
H2AC18	-8508.5
H2AC19	-8508.5
H2BC14	-8351.0
H2BC10	-7996.0
H2BC6	-7868.0
H3-3B	-7606.0
DNMT3B	-7405.0
H2BC26	-7172.0
H2AC20	-7047.0
H2BC9	-6817.5
H3C7	-6817.5
H3C1	-6297.0
DNMT3L	-5863.0
H3C8	-5843.0
H2AC7	-5765.5
H2BC7	-5765.5
DNMT1	-5746.0
H2AJ	-5637.0
H3C11	-5634.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
H2AC14	-9055.0
H2AC18	-8508.5
H2AC19	-8508.5
H2BC14	-8351.0
H2BC10	-7996.0
H2BC6	-7868.0
H3-3B	-7606.0
DNMT3B	-7405.0
H2BC26	-7172.0
H2AC20	-7047.0
H2BC9	-6817.5
H3C7	-6817.5
H3C1	-6297.0
DNMT3L	-5863.0
H3C8	-5843.0
H2AC7	-5765.5
H2BC7	-5765.5
DNMT1	-5746.0
H2AJ	-5637.0
H3C11	-5634.0
H2AZ1	-5518.0
H2AZ2	-5446.0
H2BC21	-5353.0
H4C6	-5281.0
H2BC4	-4894.0
H3C4	-4520.0
H4C1	-4509.0
H2BC15	-4097.0
DNMT3A	-3281.0
H2BC8	-2215.0
H2BC1	-2085.0
H2BC13	-1868.0
H2AX	-1254.0
H3C3	-1137.0
H4C13	-1123.0
H2AC8	-1100.0
H4C2	28.0
H3-3A	416.0
H2BC12	1033.0
H2BC17	1260.0
H4C4	1764.0
H2BC3	2104.0
H4C16	3231.0
H2BC11	3319.0
H4C5	3614.0
H3C6	3911.0
H2BC5	4322.0
H2AC6	4351.0
H3C10	5496.0
H4C12	6130.0
H3C2	7198.0
H4C11	7529.0
H4C3	9304.0
H4C9	9476.0
UHRF1	9576.0
H4C8	9710.0
H2AC4	10033.0
H3C12	10189.0

---

REACTOME_BIOLOGICAL_OXIDATIONS

REACTOME_BIOLOGICAL_OXIDATIONS

	427
set	REACTOME_BIOLOGICAL_OXIDATIONS
setSize	210
pANOVA	0.00562
s.dist	0.111
p.adjustANOVA	0.21

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP4A11	11830
UGT2B7	11819
GSTA1	11740
CYP4A22	11687
GGT6	11487
FMO3	11330
ABHD10	11317
ADH7	11246
ACSM2B	11245
ALDH1B1	11193
AOC3	11019
NNMT	10882
CYP2B6	10826
CYP4F8	10772
ACSM1	10763
ACSM4	10762
AKR7A2	10743
SULT1B1	10691
ACSM2A	10567
CYP4F2	10550

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP4A11	11830
UGT2B7	11819
GSTA1	11740
CYP4A22	11687
GGT6	11487
FMO3	11330
ABHD10	11317
ADH7	11246
ACSM2B	11245
ALDH1B1	11193
AOC3	11019
NNMT	10882
CYP2B6	10826
CYP4F8	10772
ACSM1	10763
ACSM4	10762
AKR7A2	10743
SULT1B1	10691
ACSM2A	10567
CYP4F2	10550
CYP4F12	10546
CYP21A2	10418
CHAC2	10357
CYP2C19	10225
MGST1	10180
ADH4	10079
MAT1A	9960
ADH1B	9865
CES3	9833
CYP4F11	9821
GSTA3	9777
UGT2A1	9703
PTGES3	9580
TRMT112	9499
UGT2B15	9450
MTR	9363
CMBL	9336
AOC1	9335
UGT2B4	9241
CES2	9178
ALDH3A1	9071
GGT5	8942
GLYATL1	8784
GSTM2	8659
CYP2A13	8578
CYP26A1	8502
AADAC	8375
AIP	8329
UGT1A5	8133
MTARC1	8050
ALDH2	7973
CYP1A2	7962
CYP7B1	7934
UGT2A3	7910
SULT2B1	7871
CYP2C8	7829
UGT1A1	7778
CES1	7727
UGT1A3	7679
GLYAT	7641
UGT2B11	7510
UGT1A4	7508
TBXAS1	7422
CNDP2	7249
CYP7A1	7095
CYP4B1	7064
CYP2A7	7015
DPEP2	6912
POR	6881
NCOA2	6763
UGT3A1	6728
CYP2R1	6680
CYP2J2	6655
OPLAH	6594
GGCT	6486
SLC35B2	6449
FMO2	6402
ABHD14B	6199
CYP8B1	6122
DPEP3	6085
NR1H4	6014
SULT1A1	5940
UGT1A6	5809
GSTP1	5796
MAT2A	5747
CYP4F3	5708
UGT2B17	5633
ESD	5600
CYP2W1	5494
CYP3A4	5241
GGT1	5145
RXRA	5055
NAT2	4379
UGP2	4343
AHCY	4254
ARNT	4228
AKR1A1	4179
CHAC1	3903
CYP2D6	3850
COMT	3600
UGT1A9	3580
GSS	3520
CYP2S1	3502
UGT1A7	3316
ARNT2	3278
GLYATL2	3074
BPHL	2723
ACY3	2510
POMC	2442
DPEP1	2302
UGT2A2	2278
TPMT	2033
GCLM	1888
GLYATL3	1870
UGT1A10	1717
CYP19A1	1684
GSTZ1	1533
CYP4F22	1466
CYP39A1	1400
UGT3A2	1297
UGT1A8	1210
GSTO1	1174
MGST3	928
GCLC	726
CYP3A7	634
CYP1A1	453
FDXR	351
MAT2B	13
SULT1C4	-239
ADH5	-300
GSTM4	-359
AOC2	-379
TPST1	-536
SLC26A2	-631
ACSS1	-668
ACY1	-755
AKR7L	-764
MTRR	-994
FMO1	-1171
CYP1B1	-1199
N6AMT1	-1383
NQO2	-1440
SULT2A1	-1546
SULT6B1	-1646
SLC35D1	-1933
NCOA1	-1968
AKR7A3	-2530
AHR	-2586
CYP2C18	-2649
BPNT1	-2769
SLC35B3	-3085
NAT1	-3234
CYB5R3	-3426
ADH1A	-3671
GSTA4	-3749
CYP4V2	-3798
PTGIS	-3808
TPST2	-4078
EPHX1	-4081
SMOX	-4102
CYP27A1	-4243
SULT1E1	-4593
ADH6	-4671
BPNT2	-4732
PODXL2	-4882
CYP24A1	-4960
MGST2	-5054
SLC26A1	-5505
CYP2U1	-5594
SULT1A2	-5626
CYB5B	-5759
CYP2C9	-5808
CYP3A43	-5845
MTARC2	-5891
ADH1C	-5978
UGDH	-6047
CYP2F1	-6075
AS3MT	-6381
CYP11B2	-6410
HSP90AB1	-6618
GSTM1	-6624
PTGS1	-6714
HPGDS	-6772
CYP46A1	-6890
FDX1	-6904
CYP11A1	-6998
GSTO2	-7071
CYP11B1	-7086
GGT7	-7141
GSTM3	-7161
CYP51A1	-7184
SULT4A1	-7213
CYP26B1	-7253
PAPSS2	-7288
ACSS2	-7360
ALDH1A1	-7563
SULT1C2	-7737
CYP2E1	-8019
PAPSS1	-8060
CBR3	-8147
FDX2	-8306
CYP27B1	-8500
ACSM5	-8537
GSTK1	-8707
PAOX	-8909
GSTM5	-9309
CYP26C1	-9377
GSTA5	-9738
GSTA2	-9914
CYP3A5	-9938

---

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT

	77
set	REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT
setSize	58
pANOVA	0.0061
s.dist	0.208
p.adjustANOVA	0.218

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TIMM23	11393
CHCHD5	10727
TIMM17A	10698
TOMM70	10308
TIMM13	10272
GRPEL2	10146
COA6	9923
PMPCB	9889
ATP5F1B	9860
HSPA9	9277
HSCB	9244
SLC25A4	9201
TOMM5	9173
SAMM50	8383
TIMM8B	8342
TOMM40	7967
PAM16	7488
FXN	7399
PITRM1	7353
COX19	7176

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TIMM23	11393
CHCHD5	10727
TIMM17A	10698
TOMM70	10308
TIMM13	10272
GRPEL2	10146
COA6	9923
PMPCB	9889
ATP5F1B	9860
HSPA9	9277
HSCB	9244
SLC25A4	9201
TOMM5	9173
SAMM50	8383
TIMM8B	8342
TOMM40	7967
PAM16	7488
FXN	7399
PITRM1	7353
COX19	7176
CHCHD4	6778
TOMM22	6733
ACO2	6027
COQ2	5979
TIMM21	5684
BCS1L	5491
ATP5MC1	5259
TIMM9	5185
CS	4490
SLC25A12	3709
TOMM7	3453
TOMM20	3437
COA4	3027
HSPD1	2174
CHCHD2	2156
GRPEL1	1675
CYC1	1649
VDAC1	1207
ATP5F1A	1173
TIMM10B	1088
TOMM6	404
CHCHD7	90
SLC25A13	-464
NDUFB8	-1302
MTX2	-1308
TIMM22	-1618
CMC2	-1984
CHCHD3	-2390
COX17	-4103
TIMM44	-4679
PMPCA	-5105
GFER	-5273
DNAJC19	-5509
TIMM10	-6118
TIMM50	-6518
CHCHD10	-7149
MTX1	-8786
LDHD	-9835

---

REACTOME_LGI_ADAM_INTERACTIONS

REACTOME_LGI_ADAM_INTERACTIONS

	990
set	REACTOME_LGI_ADAM_INTERACTIONS
setSize	14
pANOVA	0.00611
s.dist	-0.423
p.adjustANOVA	0.218

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LGI1	-9345
LGI2	-8671
CACNG8	-8494
CACNG3	-7798
LGI3	-6678
CACNG4	-6374
ADAM11	-6242
STX1A	-2588
DLG4	-2534
ADAM23	-1840
LGI4	-783
CACNG2	-111
ADAM22	-86
STX1B	10018

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LGI1	-9345
LGI2	-8671
CACNG8	-8494
CACNG3	-7798
LGI3	-6678
CACNG4	-6374
ADAM11	-6242
STX1A	-2588
DLG4	-2534
ADAM23	-1840
LGI4	-783
CACNG2	-111
ADAM22	-86
STX1B	10018

---

REACTOME_FORMATION_OF_LATERAL_PLATE_MESODERM

REACTOME_FORMATION_OF_LATERAL_PLATE_MESODERM

	1614
set	REACTOME_FORMATION_OF_LATERAL_PLATE_MESODERM
setSize	5
pANOVA	0.0063
s.dist	-0.705
p.adjustANOVA	0.22

Top enriched genes

Top 20 genes

GeneID	Gene Rank
BMP4	-8275
IHH	-7233
GATA4	-6975
FOXF1	-6059
SHH	-5395

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
BMP4	-8275
IHH	-7233
GATA4	-6975
FOXF1	-6059
SHH	-5395

---

REACTOME_MRNA_SPLICING

REACTOME_MRNA_SPLICING

	1143
set	REACTOME_MRNA_SPLICING
setSize	197
pANOVA	0.00693
s.dist	0.112
p.adjustANOVA	0.237

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SNRNP35	11224
SNRPD1	11129
SNRNP40	10590
MAGOH	10465
PTBP1	10270
SRSF1	9991
PRCC	9839
SNRPD2	9791
IK	9767
WBP11	9745
HNRNPA1	9695
SNRPG	9553
ZMAT2	9512
RBM25	9496
POLR2D	9470
RBM8A	9403
AQR	9331
PCBP2	9322
POLR2H	9192
PCBP1	9162

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SNRNP35	11224
SNRPD1	11129
SNRNP40	10590
MAGOH	10465
PTBP1	10270
SRSF1	9991
PRCC	9839
SNRPD2	9791
IK	9767
WBP11	9745
HNRNPA1	9695
SNRPG	9553
ZMAT2	9512
RBM25	9496
POLR2D	9470
RBM8A	9403
AQR	9331
PCBP2	9322
POLR2H	9192
PCBP1	9162
DHX8	8856
POLR2C	8572
SNRPE	8476
PRPF6	8445
SNRPA	8307
SYF2	8258
PRPF40A	8068
SF3A1	8040
PRPF3	7961
POLR2G	7857
MFAP1	7837
SNRPN	7794
SNRPC	7210
U2AF2	7099
HNRNPF	7061
CWC25	6882
NCBP2	6845
USP39	6673
TCERG1	6657
SAP18	6582
YBX1	6453
SNRPB	6432
U2SURP	6405
GTF2F2	6404
DHX16	6200
HNRNPA2B1	6153
HNRNPK	5904
RBM39	5866
PPIL3	5773
WBP4	5748
RBM5	5672
NSRP1	5654
DHX38	5605
SRSF2	5504
TXNL4A	5487
EIF4A3	5481
RNPC3	5462
POLR2E	5439
PUF60	5410
CACTIN	5338
PHF5A	5288
BUD31	5260
CWC27	5256
SF3B3	5205
PRPF38A	5135
SNRNP27	4962
DHX15	4872
DDX46	4759
SRSF3	4745
HNRNPU	4733
HNRNPM	4503
SRRT	4443
SF3B2	4382
C9orf78	4303
CTNNBL1	4255
SNRNP48	4168
HSPA8	4148
PLRG1	4074
RBM42	4030
SRRM2	3890
SF3A2	3886
DHX9	3672
LSM3	3671
SRSF11	3524
LUC7L3	3471
SRSF10	3418
SF3B5	3198
RBM7	3169
NCBP1	3154
HNRNPD	3115
SRSF9	3103
SF3B6	3078
EFTUD2	3033
DDX41	3013
CASC3	2989
MTREX	2962
ISY1	2811
SNRNP200	2741
PRPF8	2699
ACIN1	2667
CDC5L	2651
ZCRB1	2597
ZNF830	2583
SNRNP70	2534
SNRPD3	2471
RBM17	2398
HNRNPH1	2261
POLR2F	2100
SNU13	1938
SNW1	1887
LENG1	1831
SART1	1827
PPIL1	1820
DDX42	1800
POLR2L	1774
RBM22	1700
FAM32A	1682
SLU7	1240
HNRNPC	1191
PPWD1	1073
TRA2B	1063
DNAJC8	1056
GTF2F1	1054
SF3B1	941
CCAR1	907
DDX5	877
PPP1R8	862
U2AF1L4	769
PRPF31	659
LSM5	628
CDC40	490
HNRNPL	471
PPIL4	437
SMU1	274
POLR2A	197
LSM4	155
YJU2	80
LSM7	39
RNPS1	23
LSM2	-66
TFIP11	-259
HNRNPR	-270
SF1	-394
CRNKL1	-554
PPIH	-760
LSM8	-1007
CWC15	-1015
DDX39B	-1065
PPIE	-1129
SRSF4	-1369
BUD13	-1774
WDR70	-1844
POLR2B	-2172
ALYREF	-2211
SNRNP25	-2270
SNIP1	-2283
SRSF8	-2411
SRSF7	-2785
PRKRIP1	-2799
XAB2	-2915
SF3A3	-2955
PPIL2	-3001
CHERP	-3284
MAGOHB	-3299
PRPF4	-3424
SMNDC1	-3443
POLR2K	-3444
PNN	-3727
PRPF19	-4002
SNRPB2	-4106
CWC22	-4235
SNRPA1	-4512
DHX35	-4571
DDX23	-5135
UBL5	-5231
CCDC12	-5473
PPIG	-5489
PRPF18	-5652
SUGP1	-5701
LSM6	-5749
SRSF5	-5762
GPATCH1	-5907
SNRPF	-6098
PDCD7	-6119
ZMAT5	-6279
POLR2I	-6444
GCFC2	-6546
SF3B4	-6837
SRRM1	-7207
CWF19L2	-7282
SRSF6	-7523
BCAS2	-7608
HNRNPA3	-7684
SDE2	-8464
SRSF12	-8751
FUS	-9390
POLR2J	-9903

---

REACTOME_FERTILIZATION

REACTOME_FERTILIZATION

	53
set	REACTOME_FERTILIZATION
setSize	26
pANOVA	0.00715
s.dist	0.305
p.adjustANOVA	0.238

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ACR	11440
SPAM1	10938
CATSPER4	10289
HVCN1	9874
ZP4	9699
OVGP1	9662
IZUMO1	8414
ZP1	8005
CATSPER3	6932
CATSPERG	6712
IZUMO3	6300
ADAM30	6149
ADAM2	6086
CD9	5291
CATSPERB	4123
CATSPER1	3849
KCNU1	2755
B4GALT1	2128
CATSPERD	2092
ZP3	980

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ACR	11440
SPAM1	10938
CATSPER4	10289
HVCN1	9874
ZP4	9699
OVGP1	9662
IZUMO1	8414
ZP1	8005
CATSPER3	6932
CATSPERG	6712
IZUMO3	6300
ADAM30	6149
ADAM2	6086
CD9	5291
CATSPERB	4123
CATSPER1	3849
KCNU1	2755
B4GALT1	2128
CATSPERD	2092
ZP3	980
ADAM20	455
ADAM21	-263
CATSPER2	-946
ZP2	-3789
IZUMO2	-5487
IZUMO4	-9317

---

REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION

REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION

	525
set	REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION
setSize	10
pANOVA	0.00725
s.dist	-0.49
p.adjustANOVA	0.238

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GSC	-8815
SOX2	-8750
CDX2	-8378
EOMES	-7078
GATA6	-6433
DKK1	-5793
HHEX	-5155
TSC22D1	-4982
POU5F1	5312
NANOG	5868

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GSC	-8815
SOX2	-8750
CDX2	-8378
EOMES	-7078
GATA6	-6433
DKK1	-5793
HHEX	-5155
TSC22D1	-4982
POU5F1	5312
NANOG	5868

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report