date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch
x
A1BG -0.0067793
A1BG-AS1 -0.0101015
A1CF -0.0013004
A2M 0.0067466
A2M-AS1 -0.0139460
A2ML1 0.0030133

Here are some metrics about the input data profile:

Profiling data metrics
Profile metrics
num_genesets 1654
num_genes_in_profile 22007
duplicated_genes_present 0
num_profile_genes_in_sets 10383
num_profile_genes_not_in_sets 11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt
Gene set metrics
Gene sets metrics
num_genesets 1654
num_genesets_excluded 365
num_genesets_included 1289

Differential pathway expression


Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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## in kable. kableExtra can customize either HTML or LaTeX outputs. See
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set setSize pANOVA s.dist p.adjustANOVA
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.56e-06 0.2980 0.00207
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 2.52e-06 0.2810 0.00207
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 2.83e-05 0.2310 0.01230
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 3.00e-05 0.2360 0.01230
REACTOME INTERLEUKIN 10 SIGNALING 43 4.38e-05 0.3600 0.01230
REACTOME NONSENSE MEDIATED DECAY NMD 107 4.48e-05 0.2280 0.01230
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 1.24e-04 0.0626 0.02900
REACTOME SELENOAMINO ACID METABOLISM 108 1.95e-04 0.2070 0.04000
REACTOME SIGNALING BY INTERLEUKINS 444 2.95e-04 0.1000 0.05380
REACTOME INFLUENZA INFECTION 149 6.19e-04 0.1620 0.09840
REACTOME KERATINIZATION 210 6.59e-04 -0.1360 0.09840
REACTOME SIGNALING BY ROBO RECEPTORS 206 8.71e-04 0.1350 0.11900
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 9.57e-04 0.1510 0.12100
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 1.04e-03 0.2160 0.12100
REACTOME FCGR ACTIVATION 11 1.20e-03 0.5640 0.12900
REACTOME NEUTROPHIL DEGRANULATION 460 1.27e-03 0.0877 0.12900
REACTOME CELLULAR RESPONSE TO STARVATION 147 1.37e-03 0.1530 0.12900
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.41e-03 0.1670 0.12900
REACTOME CD22 MEDIATED BCR REGULATION 5 1.78e-03 0.8070 0.15400
REACTOME TRANSLATION 278 2.18e-03 0.1070 0.17900
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 2.31e-03 -0.1580 0.18100
REACTOME REGULATION OF SIGNALING BY CBL 22 3.27e-03 0.3620 0.23800
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 3.34e-03 -0.1470 0.23800
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 3.52e-03 0.0832 0.24100
REACTOME INNATE IMMUNE SYSTEM 1002 3.79e-03 0.0540 0.24300
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 3.84e-03 0.2910 0.24300
REACTOME ACTIVATION OF C3 AND C5 6 4.92e-03 -0.6630 0.29900
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 5.62e-03 0.2920 0.33000
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 6.07e-03 0.0614 0.34100
REACTOME METABOLISM OF RNA 675 6.23e-03 0.0617 0.34100
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 6.50e-03 0.6420 0.34300
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 6.69e-03 0.0840 0.34300
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 7.08e-03 -0.3670 0.35200
REACTOME OLFACTORY SIGNALING PATHWAY 348 7.53e-03 -0.0834 0.36400
REACTOME PI3K AKT SIGNALING IN CANCER 103 8.42e-03 0.1500 0.38400
REACTOME PD 1 SIGNALING 21 8.75e-03 0.3300 0.38400
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 8.86e-03 0.2080 0.38400
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 8.90e-03 0.5040 0.38400
REACTOME TCR SIGNALING 113 1.07e-02 0.1390 0.45200
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 1.16e-02 0.2980 0.46700
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 1.19e-02 -0.5930 0.46700
REACTOME PI 3K CASCADE FGFR3 17 1.19e-02 0.3520 0.46700
REACTOME RRNA PROCESSING 192 1.33e-02 0.1040 0.48900
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 1.33e-02 0.0616 0.48900
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 1.34e-02 0.0831 0.48900
REACTOME RHOT1 GTPASE CYCLE 5 1.37e-02 0.6370 0.48900
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.47e-02 0.1340 0.50500
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 1.48e-02 0.4250 0.50500
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.53e-02 0.1460 0.50900
REACTOME RHO GTPASE CYCLE 423 1.57e-02 0.0685 0.50900


Results (complete table)


Click HERE to show results for all gene sets

Complete results
set setSize pANOVA s.dist p.adjustANOVA
REACTOME EUKARYOTIC TRANSLATION ELONGATION 87 1.56e-06 0.298000 0.00207
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY 94 2.52e-06 0.281000 0.00207
REACTOME EUKARYOTIC TRANSLATION INITIATION 110 2.83e-05 0.231000 0.01230
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE 105 3.00e-05 0.236000 0.01230
REACTOME INTERLEUKIN 10 SIGNALING 43 4.38e-05 0.360000 0.01230
REACTOME NONSENSE MEDIATED DECAY NMD 107 4.48e-05 0.228000 0.01230
REACTOME RNA POLYMERASE II TRANSCRIPTION 1336 1.24e-04 0.062600 0.02900
REACTOME SELENOAMINO ACID METABOLISM 108 1.95e-04 0.207000 0.04000
REACTOME SIGNALING BY INTERLEUKINS 444 2.95e-04 0.100000 0.05380
REACTOME INFLUENZA INFECTION 149 6.19e-04 0.162000 0.09840
REACTOME KERATINIZATION 210 6.59e-04 -0.136000 0.09840
REACTOME SIGNALING BY ROBO RECEPTORS 206 8.71e-04 0.135000 0.11900
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS 161 9.57e-04 0.151000 0.12100
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER 77 1.04e-03 0.216000 0.12100
REACTOME FCGR ACTIVATION 11 1.20e-03 0.564000 0.12900
REACTOME NEUTROPHIL DEGRANULATION 460 1.27e-03 0.087700 0.12900
REACTOME CELLULAR RESPONSE TO STARVATION 147 1.37e-03 0.153000 0.12900
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL 122 1.41e-03 0.167000 0.12900
REACTOME CD22 MEDIATED BCR REGULATION 5 1.78e-03 0.807000 0.15400
REACTOME TRANSLATION 278 2.18e-03 0.107000 0.17900
REACTOME FORMATION OF THE CORNIFIED ENVELOPE 125 2.31e-03 -0.158000 0.18100
REACTOME REGULATION OF SIGNALING BY CBL 22 3.27e-03 0.362000 0.23800
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX 134 3.34e-03 -0.147000 0.23800
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS 418 3.52e-03 0.083200 0.24100
REACTOME INNATE IMMUNE SYSTEM 1002 3.79e-03 0.054000 0.24300
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY 33 3.84e-03 0.291000 0.24300
REACTOME ACTIVATION OF C3 AND C5 6 4.92e-03 -0.663000 0.29900
REACTOME GENERATION OF SECOND MESSENGER MOLECULES 30 5.62e-03 0.292000 0.33000
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 688 6.07e-03 0.061400 0.34100
REACTOME METABOLISM OF RNA 675 6.23e-03 0.061700 0.34100
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION 6 6.50e-03 0.642000 0.34300
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES 353 6.69e-03 0.084000 0.34300
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS 18 7.08e-03 -0.367000 0.35200
REACTOME OLFACTORY SIGNALING PATHWAY 348 7.53e-03 -0.083400 0.36400
REACTOME PI3K AKT SIGNALING IN CANCER 103 8.42e-03 0.150000 0.38400
REACTOME PD 1 SIGNALING 21 8.75e-03 0.330000 0.38400
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S 53 8.86e-03 0.208000 0.38400
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE 9 8.90e-03 0.504000 0.38400
REACTOME TCR SIGNALING 113 1.07e-02 0.139000 0.45200
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR 24 1.16e-02 0.298000 0.46700
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE 6 1.19e-02 -0.593000 0.46700
REACTOME PI 3K CASCADE FGFR3 17 1.19e-02 0.352000 0.46700
REACTOME RRNA PROCESSING 192 1.33e-02 0.104000 0.48900
REACTOME NERVOUS SYSTEM DEVELOPMENT 552 1.33e-02 0.061600 0.48900
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS 299 1.34e-02 0.083100 0.48900
REACTOME RHOT1 GTPASE CYCLE 5 1.37e-02 0.637000 0.48900
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK 111 1.47e-02 0.134000 0.50500
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES 11 1.48e-02 0.425000 0.50500
REACTOME SARS COV 1 HOST INTERACTIONS 92 1.53e-02 0.146000 0.50900
REACTOME RHO GTPASE CYCLE 423 1.57e-02 0.068500 0.50900
REACTOME MITOCHONDRIAL UNCOUPLING 5 1.58e-02 0.623000 0.50900
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION 74 1.70e-02 0.160000 0.52700
REACTOME SIGNAL AMPLIFICATION 33 1.75e-02 0.239000 0.52700
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL 19 1.76e-02 -0.315000 0.52700
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX 39 1.77e-02 0.220000 0.52700
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION 145 1.80e-02 0.114000 0.52900
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ 6 1.89e-02 -0.554000 0.53400
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 250 1.94e-02 0.085900 0.53400
REACTOME RUNX3 REGULATES WNT SIGNALING 8 1.95e-02 0.477000 0.53400
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS 28 1.98e-02 0.254000 0.53400
REACTOME MRNA EDITING 10 2.00e-02 0.425000 0.53400
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS 16 2.02e-02 0.335000 0.53400
REACTOME LYSINE CATABOLISM 12 2.08e-02 0.385000 0.53700
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES 10 2.11e-02 0.421000 0.53700
REACTOME SIGNALING BY GPCR 673 2.13e-02 0.052100 0.53700
REACTOME SENSORY PERCEPTION 555 2.16e-02 -0.057000 0.53700
REACTOME PI 3K CASCADE FGFR2 22 2.20e-02 0.282000 0.54000
REACTOME ECM PROTEOGLYCANS 73 2.41e-02 -0.153000 0.54600
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS 93 2.42e-02 0.135000 0.54600
REACTOME S PHASE 159 2.45e-02 0.103000 0.54600
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES 55 2.47e-02 0.175000 0.54600
REACTOME PRC2 METHYLATES HISTONES AND DNA 65 2.48e-02 -0.161000 0.54600
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL 129 2.58e-02 0.114000 0.54600
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX 13 2.58e-02 0.357000 0.54600
REACTOME SIGNALING BY NOTCH1 69 2.59e-02 0.155000 0.54600
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21 59 2.67e-02 0.167000 0.54600
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING 38 2.71e-02 0.207000 0.54600
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 44 2.73e-02 0.192000 0.54600
REACTOME ESTROGEN BIOSYNTHESIS 6 2.76e-02 -0.519000 0.54600
REACTOME MAPK FAMILY SIGNALING CASCADES 314 2.78e-02 0.072200 0.54600
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN 11 2.79e-02 -0.383000 0.54600
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION 15 2.79e-02 0.328000 0.54600
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM 20 2.79e-02 -0.284000 0.54600
REACTOME CYP2E1 REACTIONS 10 2.79e-02 0.401000 0.54600
REACTOME COSTIMULATION BY THE CD28 FAMILY 64 2.96e-02 0.157000 0.55900
REACTOME PI 3K CASCADE FGFR1 21 2.98e-02 0.274000 0.55900
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION 19 3.00e-02 0.288000 0.55900
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS 7 3.09e-02 0.471000 0.55900
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER 54 3.12e-02 0.170000 0.55900
REACTOME PEPTIDE HORMONE BIOSYNTHESIS 13 3.14e-02 0.345000 0.55900
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY 84 3.17e-02 0.136000 0.55900
REACTOME NCAM1 INTERACTIONS 41 3.17e-02 -0.194000 0.55900
REACTOME NEGATIVE REGULATION OF FLT3 15 3.19e-02 0.320000 0.55900
REACTOME SIGNALING BY FGFR 85 3.25e-02 0.134000 0.55900
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH 62 3.25e-02 -0.157000 0.55900
REACTOME EICOSANOID LIGAND BINDING RECEPTORS 14 3.27e-02 0.330000 0.55900
REACTOME INFECTIOUS DISEASE 910 3.33e-02 0.041600 0.56300
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS 8 3.37e-02 0.434000 0.56500
REACTOME FLT3 SIGNALING 38 3.42e-02 0.199000 0.56700
REACTOME KETONE BODY METABOLISM 9 3.47e-02 -0.407000 0.56800
REACTOME INTERLEUKIN 1 FAMILY SIGNALING 146 3.50e-02 0.101000 0.56800
REACTOME HDL REMODELING 10 3.68e-02 0.381000 0.59200
REACTOME DIGESTION AND ABSORPTION 22 3.80e-02 -0.255000 0.59200
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS 24 3.81e-02 0.244000 0.59200
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12 22 3.84e-02 0.255000 0.59200
REACTOME MET ACTIVATES RAP1 AND RAC1 11 3.87e-02 0.360000 0.59200
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES 38 3.88e-02 0.194000 0.59200
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION 60 3.89e-02 -0.154000 0.59200
REACTOME CD209 DC SIGN SIGNALING 20 3.96e-02 -0.266000 0.59600
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS 83 4.22e-02 0.129000 0.62300
REACTOME PKMTS METHYLATE HISTONE LYSINES 64 4.25e-02 -0.147000 0.62300
REACTOME GPVI MEDIATED ACTIVATION CASCADE 35 4.26e-02 0.198000 0.62300
REACTOME REGULATION OF SIGNALING BY NODAL 9 4.29e-02 0.390000 0.62300
REACTOME TOLL LIKE RECEPTOR CASCADES 158 4.37e-02 0.093000 0.62700
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION 62 4.39e-02 -0.148000 0.62700
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS 86 4.46e-02 0.125000 0.63100
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2 17 4.51e-02 0.281000 0.63100
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION 5 4.60e-02 -0.515000 0.63100
REACTOME DNA METHYLATION 58 4.61e-02 -0.151000 0.63100
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS 36 4.62e-02 0.192000 0.63100
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS 7 4.65e-02 -0.434000 0.63100
REACTOME REGULATION OF KIT SIGNALING 16 4.76e-02 0.286000 0.63600
REACTOME TRANSPORT OF ORGANIC ANIONS 10 4.76e-02 0.362000 0.63600
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING 28 4.85e-02 0.215000 0.63600
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS 118 4.86e-02 -0.105000 0.63600
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN 13 4.88e-02 -0.316000 0.63600
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS 9 5.05e-02 0.376000 0.64200
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY 46 5.07e-02 0.166000 0.64200
REACTOME XENOBIOTICS 22 5.19e-02 0.239000 0.64200
REACTOME G2 PHASE 5 5.20e-02 0.502000 0.64200
REACTOME VITAMIN C ASCORBATE METABOLISM 8 5.21e-02 0.397000 0.64200
REACTOME VITAMIN D CALCIFEROL METABOLISM 12 5.22e-02 0.324000 0.64200
REACTOME INTESTINAL ABSORPTION 5 5.28e-02 -0.500000 0.64200
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION 12 5.31e-02 0.322000 0.64200
REACTOME MRNA EDITING C TO U CONVERSION 8 5.39e-02 0.394000 0.64200
REACTOME INTERLEUKIN 12 FAMILY SIGNALING 53 5.39e-02 0.153000 0.64200
REACTOME INTERLEUKIN 1 SIGNALING 110 5.39e-02 0.106000 0.64200
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING 26 5.39e-02 0.218000 0.64200
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS 30 5.43e-02 0.203000 0.64200
REACTOME SIGNALING BY LEPTIN 11 5.57e-02 -0.333000 0.64600
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE 6 5.63e-02 -0.450000 0.64600
REACTOME GROWTH HORMONE RECEPTOR SIGNALING 24 5.66e-02 -0.225000 0.64600
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS 13 5.70e-02 0.305000 0.64600
REACTOME SIGNALING BY ALK 26 5.79e-02 0.215000 0.64600
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING 5 5.79e-02 0.490000 0.64600
REACTOME SIGNALING BY FGFR2 72 5.84e-02 0.129000 0.64600
REACTOME INITIAL TRIGGERING OF COMPLEMENT 21 5.89e-02 -0.238000 0.64600
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES 12 5.92e-02 0.314000 0.64600
REACTOME SYNTHESIS OF KETONE BODIES 8 5.94e-02 -0.385000 0.64600
REACTOME RAB GERANYLGERANYLATION 57 5.94e-02 0.144000 0.64600
REACTOME G ALPHA S SIGNALLING EVENTS 155 5.95e-02 0.087700 0.64600
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING 33 5.98e-02 0.189000 0.64600
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN 15 6.03e-02 -0.280000 0.64700
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS 87 6.12e-02 0.116000 0.65300
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR 8 6.23e-02 0.381000 0.65500
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES 66 6.24e-02 -0.133000 0.65500
REACTOME GLUCURONIDATION 23 6.29e-02 -0.224000 0.65500
REACTOME ORC1 REMOVAL FROM CHROMATIN 70 6.31e-02 0.128000 0.65500
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM 23 6.34e-02 0.224000 0.65500
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX 15 6.44e-02 0.276000 0.66100
REACTOME COLLAGEN DEGRADATION 61 6.61e-02 -0.136000 0.66100
REACTOME SIGNALING BY FGFR1 49 6.62e-02 0.152000 0.66100
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE 109 6.67e-02 0.102000 0.66100
REACTOME MET ACTIVATES PI3K AKT SIGNALING 6 6.70e-02 0.432000 0.66100
REACTOME LIPID PARTICLE ORGANIZATION 6 6.74e-02 0.431000 0.66100
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3 94 6.80e-02 0.109000 0.66100
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN 6 6.86e-02 0.429000 0.66100
REACTOME ADAPTIVE IMMUNE SYSTEM 729 6.86e-02 0.039600 0.66100
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K 12 6.89e-02 0.303000 0.66100
REACTOME RHO GTPASES ACTIVATE IQGAPS 31 6.94e-02 -0.188000 0.66100
REACTOME G ALPHA I SIGNALLING EVENTS 304 6.98e-02 0.060500 0.66100
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION 89 7.00e-02 0.111000 0.66100
REACTOME HATS ACETYLATE HISTONES 129 7.08e-02 -0.092100 0.66100
REACTOME ASPARTATE AND ASPARAGINE METABOLISM 11 7.15e-02 0.314000 0.66100
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING 45 7.19e-02 0.155000 0.66100
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3 24 7.24e-02 0.212000 0.66100
REACTOME CELLULAR RESPONSES TO STIMULI 779 7.25e-02 0.037800 0.66100
REACTOME KINESINS 59 7.39e-02 -0.135000 0.66100
REACTOME SYNTHESIS OF DNA 119 7.43e-02 0.094700 0.66100
REACTOME MET ACTIVATES PTPN11 5 7.44e-02 0.461000 0.66100
REACTOME DAP12 SIGNALING 27 7.49e-02 0.198000 0.66100
REACTOME METABOLISM OF LIPIDS 709 7.53e-02 0.039200 0.66100
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION 90 7.55e-02 -0.108000 0.66100
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP 41 7.59e-02 -0.160000 0.66100
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING 32 7.61e-02 0.181000 0.66100
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS 82 7.65e-02 -0.113000 0.66100
REACTOME OPIOID SIGNALLING 89 7.66e-02 0.109000 0.66100
REACTOME PASSIVE TRANSPORT BY AQUAPORINS 13 7.67e-02 0.284000 0.66100
REACTOME GAP JUNCTION ASSEMBLY 36 7.79e-02 -0.170000 0.66100
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION 7 7.80e-02 0.385000 0.66100
REACTOME PHOSPHOLIPID METABOLISM 201 7.81e-02 0.072100 0.66100
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET 8 7.83e-02 0.359000 0.66100
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION 12 7.84e-02 0.293000 0.66100
REACTOME AQUAPORIN MEDIATED TRANSPORT 51 7.86e-02 0.142000 0.66100
REACTOME PI 3K CASCADE FGFR4 19 7.87e-02 0.233000 0.66100
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS 12 7.90e-02 -0.293000 0.66100
REACTOME ENOS ACTIVATION 11 8.00e-02 0.305000 0.66700
REACTOME AMINO ACID CONJUGATION 9 8.07e-02 -0.336000 0.66700
REACTOME G PROTEIN ACTIVATION 24 8.13e-02 0.206000 0.66700
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING 5 8.14e-02 0.450000 0.66700
REACTOME OTHER SEMAPHORIN INTERACTIONS 18 8.16e-02 0.237000 0.66700
REACTOME SARS COV 1 INFECTION 136 8.37e-02 0.085900 0.68000
REACTOME RSK ACTIVATION 5 8.41e-02 -0.446000 0.68000
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES 507 8.47e-02 0.044700 0.68200
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION 68 8.55e-02 -0.121000 0.68400
REACTOME FREE FATTY ACID RECEPTORS 5 8.77e-02 0.441000 0.68400
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2 29 8.84e-02 0.183000 0.68400
REACTOME NEGATIVE REGULATION OF MET ACTIVITY 20 8.93e-02 0.219000 0.68400
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE 91 9.03e-02 0.103000 0.68400
REACTOME DEFECTIVE CHSY1 CAUSES TPBS 7 9.17e-02 0.368000 0.68400
REACTOME FLT3 SIGNALING BY CBL MUTANTS 7 9.20e-02 0.368000 0.68400
REACTOME CD28 DEPENDENT VAV1 PATHWAY 11 9.22e-02 0.293000 0.68400
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 106 9.26e-02 0.094500 0.68400
REACTOME PROSTANOID LIGAND RECEPTORS 9 9.27e-02 0.324000 0.68400
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION 11 9.29e-02 0.293000 0.68400
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS 111 9.29e-02 0.092300 0.68400
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION 11 9.34e-02 -0.292000 0.68400
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR 11 9.35e-02 0.292000 0.68400
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF 53 9.40e-02 -0.133000 0.68400
REACTOME ORGANIC ANION TRANSPORT 5 9.43e-02 -0.432000 0.68400
REACTOME SUMOYLATION 179 9.46e-02 0.072400 0.68400
REACTOME MAPK6 MAPK4 SIGNALING 91 9.52e-02 0.101000 0.68400
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION 140 9.53e-02 -0.081700 0.68400
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1 25 9.63e-02 0.192000 0.68400
REACTOME SIGNALING BY FGFR3 39 9.65e-02 0.154000 0.68400
REACTOME GOLGI TO ER RETROGRADE TRANSPORT 132 9.67e-02 -0.083700 0.68400
REACTOME HEMOSTASIS 591 9.72e-02 0.039900 0.68400
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1 9 9.75e-02 0.319000 0.68400
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS 5 9.75e-02 0.428000 0.68400
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT 15 9.79e-02 -0.247000 0.68400
REACTOME RET SIGNALING 40 9.79e-02 0.151000 0.68400
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM 7 9.80e-02 0.361000 0.68400
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING 53 9.81e-02 0.131000 0.68400
REACTOME PECAM1 INTERACTIONS 12 9.84e-02 0.276000 0.68400
REACTOME GAB1 SIGNALOSOME 17 9.86e-02 0.231000 0.68400
REACTOME NICOTINATE METABOLISM 31 9.92e-02 -0.171000 0.68400
REACTOME CA2 ACTIVATED K CHANNELS 9 9.93e-02 0.317000 0.68400
REACTOME DISEASES OF PROGRAMMED CELL DEATH 96 9.96e-02 -0.097300 0.68400
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2 60 9.96e-02 0.123000 0.68400
REACTOME FCERI MEDIATED CA 2 MOBILIZATION 30 1.00e-01 0.173000 0.68600
REACTOME LEISHMANIA INFECTION 156 1.02e-01 0.075800 0.69000
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1 31 1.02e-01 0.169000 0.69000
REACTOME NONHOMOLOGOUS END JOINING NHEJ 64 1.03e-01 -0.118000 0.69000
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS 8 1.03e-01 -0.333000 0.69000
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE 52 1.04e-01 -0.130000 0.69000
REACTOME RHOF GTPASE CYCLE 40 1.04e-01 0.149000 0.69000
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3 59 1.04e-01 -0.122000 0.69000
REACTOME SIGNALING BY SCF KIT 42 1.04e-01 0.145000 0.69000
REACTOME DIGESTION OF DIETARY CARBOHYDRATE 6 1.05e-01 -0.382000 0.69200
REACTOME SARS COV 2 HOST INTERACTIONS 191 1.05e-01 0.067900 0.69200
REACTOME HDL ASSEMBLY 8 1.06e-01 0.330000 0.69300
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS 5 1.09e-01 -0.414000 0.70200
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS 12 1.09e-01 -0.267000 0.70200
REACTOME REGULATION OF FZD BY UBIQUITINATION 21 1.10e-01 0.202000 0.70200
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES 6 1.10e-01 0.377000 0.70200
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST 14 1.10e-01 0.247000 0.70200
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES 30 1.10e-01 -0.169000 0.70200
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX 9 1.10e-01 0.307000 0.70200
REACTOME IRAK4 DEFICIENCY TLR2 4 17 1.11e-01 0.223000 0.70700
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING 5 1.12e-01 -0.410000 0.70700
REACTOME FORMATION OF AXIAL MESODERM 14 1.12e-01 0.245000 0.70700
REACTOME PEXOPHAGY 11 1.13e-01 0.276000 0.70700
REACTOME INTERLEUKIN 12 SIGNALING 43 1.13e-01 0.140000 0.70700
REACTOME GAP JUNCTION DEGRADATION 12 1.14e-01 0.264000 0.70800
REACTOME TRIGLYCERIDE CATABOLISM 23 1.14e-01 0.190000 0.70800
REACTOME SIGNALING BY NOTCH2 32 1.16e-01 0.161000 0.71300
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS 101 1.17e-01 0.090300 0.71700
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE 66 1.17e-01 -0.112000 0.71700
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS 30 1.18e-01 0.165000 0.71800
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS 32 1.20e-01 0.159000 0.72400
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX 83 1.20e-01 0.098700 0.72400
REACTOME PARASITE INFECTION 57 1.21e-01 0.119000 0.72400
REACTOME M PHASE 398 1.21e-01 -0.045300 0.72400
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1 6 1.22e-01 0.365000 0.72400
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY 96 1.22e-01 0.091300 0.72400
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE 63 1.22e-01 0.113000 0.72400
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 98 1.23e-01 0.090100 0.72400
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION 15 1.23e-01 0.230000 0.72400
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME 59 1.24e-01 0.116000 0.72400
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD 7 1.24e-01 0.336000 0.72400
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 98 1.25e-01 -0.089600 0.72400
REACTOME RAC3 GTPASE CYCLE 85 1.26e-01 0.096100 0.72400
REACTOME TERMINAL PATHWAY OF COMPLEMENT 8 1.26e-01 0.313000 0.72400
REACTOME AMYLOID FIBER FORMATION 102 1.26e-01 -0.087800 0.72400
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1 16 1.26e-01 0.221000 0.72400
REACTOME SENSORY PERCEPTION OF SALTY TASTE 6 1.26e-01 0.360000 0.72500
REACTOME NICOTINAMIDE SALVAGING 19 1.27e-01 -0.202000 0.72500
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES 91 1.28e-01 -0.092400 0.72800
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA 54 1.29e-01 0.120000 0.72800
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION 9 1.29e-01 0.292000 0.72800
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE 63 1.29e-01 -0.111000 0.73000
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX 31 1.31e-01 0.157000 0.73700
REACTOME SIGNALING BY NOTCH4 80 1.32e-01 0.097500 0.73700
REACTOME RESOLUTION OF ABASIC SITES AP SITES 38 1.35e-01 0.140000 0.75300
REACTOME UNFOLDED PROTEIN RESPONSE UPR 88 1.37e-01 0.091800 0.76100
REACTOME GLUCAGON TYPE LIGAND RECEPTORS 32 1.38e-01 0.152000 0.76400
REACTOME HEME DEGRADATION 15 1.39e-01 0.221000 0.76400
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION 59 1.39e-01 0.111000 0.76400
REACTOME CHROMATIN MODIFYING ENZYMES 252 1.39e-01 -0.054100 0.76400
REACTOME PLATELET AGGREGATION PLUG FORMATION 39 1.40e-01 0.137000 0.76400
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA 25 1.40e-01 0.170000 0.76600
REACTOME REGULATION OF IFNA IFNB SIGNALING 23 1.43e-01 0.176000 0.77800
REACTOME RHOBTB3 ATPASE CYCLE 8 1.44e-01 -0.298000 0.77800
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION 8 1.44e-01 0.298000 0.77800
REACTOME P75NTR SIGNALS VIA NF KB 15 1.46e-01 0.217000 0.78200
REACTOME SIGNALING BY PTK6 54 1.46e-01 0.114000 0.78200
REACTOME RHO GTPASES ACTIVATE PKNS 86 1.46e-01 -0.090600 0.78200
REACTOME EXTRACELLULAR MATRIX ORGANIZATION 291 1.48e-01 -0.049300 0.78200
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS 51 1.48e-01 0.117000 0.78200
REACTOME CREB3 FACTORS ACTIVATE GENES 8 1.48e-01 0.295000 0.78200
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA 52 1.48e-01 0.116000 0.78200
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING 13 1.49e-01 0.231000 0.78200
REACTOME GPCR LIGAND BINDING 444 1.50e-01 0.039800 0.78600
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM 6 1.51e-01 -0.338000 0.78600
REACTOME G1 S DNA DAMAGE CHECKPOINTS 67 1.52e-01 0.101000 0.78600
REACTOME G0 AND EARLY G1 27 1.52e-01 0.159000 0.78600
REACTOME PERK REGULATES GENE EXPRESSION 31 1.52e-01 0.149000 0.78600
REACTOME CALNEXIN CALRETICULIN CYCLE 26 1.52e-01 0.162000 0.78600
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS 12 1.53e-01 -0.238000 0.78600
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY 14 1.53e-01 0.220000 0.78600
REACTOME HIV INFECTION 223 1.55e-01 0.055300 0.78700
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS 123 1.55e-01 0.074300 0.78700
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R 52 1.55e-01 0.114000 0.78700
REACTOME SOS MEDIATED SIGNALLING 7 1.55e-01 -0.310000 0.78700
REACTOME PHASE 2 PLATEAU PHASE 14 1.56e-01 -0.219000 0.78700
REACTOME RHOBTB2 GTPASE CYCLE 22 1.56e-01 0.175000 0.78700
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX 85 1.57e-01 -0.088900 0.78700
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A 26 1.57e-01 0.160000 0.78700
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING 30 1.58e-01 0.149000 0.78700
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 100 1.59e-01 -0.081600 0.78900
REACTOME FOLDING OF ACTIN BY CCT TRIC 10 1.60e-01 0.257000 0.79200
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING 9 1.62e-01 0.269000 0.80000
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION 30 1.64e-01 0.147000 0.80100
REACTOME VISUAL PHOTOTRANSDUCTION 93 1.65e-01 -0.083300 0.80100
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4 14 1.66e-01 0.214000 0.80100
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION 9 1.66e-01 -0.267000 0.80100
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS 18 1.67e-01 0.188000 0.80100
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY 11 1.68e-01 0.240000 0.80100
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING 11 1.68e-01 -0.240000 0.80100
REACTOME DARPP 32 EVENTS 24 1.70e-01 0.162000 0.80100
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS 113 1.70e-01 -0.074700 0.80100
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS 68 1.70e-01 0.096100 0.80100
REACTOME RHO GTPASE EFFECTORS 305 1.71e-01 -0.045600 0.80100
REACTOME G ALPHA Z SIGNALLING EVENTS 48 1.71e-01 0.114000 0.80100
REACTOME CALCITONIN LIKE LIGAND RECEPTORS 10 1.71e-01 0.250000 0.80100
REACTOME ALPHA DEFENSINS 6 1.72e-01 0.322000 0.80100
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY 51 1.72e-01 0.110000 0.80100
REACTOME SIGNALING BY NODAL 20 1.73e-01 0.176000 0.80100
REACTOME CD28 CO STIMULATION 32 1.73e-01 0.139000 0.80100
REACTOME IRAK1 RECRUITS IKK COMPLEX 12 1.73e-01 0.227000 0.80100
REACTOME RECYCLING PATHWAY OF L1 43 1.74e-01 -0.120000 0.80100
REACTOME BUDDING AND MATURATION OF HIV VIRION 28 1.74e-01 0.148000 0.80100
REACTOME RORA ACTIVATES GENE EXPRESSION 17 1.74e-01 -0.190000 0.80100
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K 7 1.74e-01 0.297000 0.80100
REACTOME MITOTIC PROMETAPHASE 194 1.75e-01 -0.056400 0.80100
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION 7 1.77e-01 0.295000 0.80100
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY 10 1.77e-01 -0.247000 0.80100
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE 118 1.78e-01 -0.071800 0.80100
REACTOME ATORVASTATIN ADME 9 1.78e-01 0.259000 0.80100
REACTOME INTRAFLAGELLAR TRANSPORT 50 1.78e-01 -0.110000 0.80100
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION 42 1.78e-01 0.120000 0.80100
REACTOME HDL CLEARANCE 5 1.79e-01 0.347000 0.80100
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES 27 1.79e-01 0.149000 0.80100
REACTOME DAP12 INTERACTIONS 37 1.79e-01 0.128000 0.80100
REACTOME HIV TRANSCRIPTION ELONGATION 42 1.79e-01 -0.120000 0.80100
REACTOME PROLACTIN RECEPTOR SIGNALING 15 1.79e-01 -0.200000 0.80100
REACTOME INTERLEUKIN 18 SIGNALING 8 1.80e-01 0.273000 0.80100
REACTOME TRANSPORT OF FATTY ACIDS 8 1.81e-01 0.273000 0.80100
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA 15 1.81e-01 0.199000 0.80100
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA 63 1.82e-01 -0.097300 0.80100
REACTOME ADHERENS JUNCTIONS INTERACTIONS 33 1.82e-01 -0.134000 0.80100
REACTOME DNA DOUBLE STRAND BREAK RESPONSE 74 1.82e-01 -0.089600 0.80100
REACTOME AGGREPHAGY 42 1.83e-01 -0.119000 0.80100
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION 36 1.84e-01 0.128000 0.80100
REACTOME PLASMA LIPOPROTEIN ASSEMBLY 19 1.84e-01 0.176000 0.80100
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG 7 1.84e-01 0.290000 0.80100
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING 103 1.84e-01 0.075700 0.80100
REACTOME RAP1 SIGNALLING 16 1.84e-01 0.192000 0.80100
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION 296 1.85e-01 -0.044800 0.80100
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION 8 1.86e-01 0.270000 0.80300
REACTOME REGULATION OF TP53 ACTIVITY 156 1.86e-01 0.061300 0.80300
REACTOME OPSINS 7 1.88e-01 -0.287000 0.80600
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS 66 1.88e-01 -0.093600 0.80600
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES 34 1.89e-01 0.130000 0.80600
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B 24 1.90e-01 0.155000 0.80600
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 11 1.90e-01 0.228000 0.80600
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING 5 1.90e-01 0.338000 0.80600
REACTOME DIGESTION 17 1.91e-01 -0.183000 0.80600
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES 16 1.91e-01 -0.189000 0.80800
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION 45 1.92e-01 0.112000 0.80800
REACTOME PRE NOTCH EXPRESSION AND PROCESSING 112 1.93e-01 -0.071200 0.81100
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA 15 1.94e-01 -0.194000 0.81100
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS 5 1.94e-01 -0.335000 0.81100
REACTOME MIRO GTPASE CYCLE 8 1.95e-01 0.265000 0.81100
REACTOME SIGNALING BY ERBB2 50 1.95e-01 0.106000 0.81200
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42 19 1.97e-01 0.171000 0.81500
REACTOME RAC1 GTPASE CYCLE 172 1.97e-01 0.057000 0.81500
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION 16 1.99e-01 0.186000 0.81500
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING 74 1.99e-01 0.086400 0.81500
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND 21 2.00e-01 0.161000 0.81500
REACTOME SODIUM CALCIUM EXCHANGERS 11 2.01e-01 -0.223000 0.81500
REACTOME ACTIVATION OF BH3 ONLY PROTEINS 30 2.02e-01 0.135000 0.81500
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS 42 2.02e-01 0.114000 0.81500
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS 29 2.02e-01 0.137000 0.81500
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING 11 2.03e-01 0.222000 0.81500
REACTOME ZINC TRANSPORTERS 15 2.03e-01 -0.190000 0.81500
REACTOME SIGNALING BY RNF43 MUTANTS 8 2.03e-01 0.260000 0.81500
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS 16 2.04e-01 -0.184000 0.81500
REACTOME SARS COV INFECTIONS 392 2.04e-01 0.037300 0.81500
REACTOME CDC42 GTPASE CYCLE 144 2.05e-01 0.061200 0.81500
REACTOME DISEASES OF IMMUNE SYSTEM 29 2.05e-01 0.136000 0.81500
REACTOME HOST INTERACTIONS OF HIV FACTORS 127 2.05e-01 0.065100 0.81500
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS 7 2.05e-01 0.276000 0.81500
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES 43 2.05e-01 -0.112000 0.81500
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS 33 2.07e-01 0.127000 0.81600
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS 37 2.08e-01 0.120000 0.81600
REACTOME INTERLEUKIN 23 SIGNALING 9 2.08e-01 0.242000 0.81600
REACTOME HEDGEHOG LIGAND BIOGENESIS 64 2.08e-01 0.091000 0.81600
REACTOME FOXO MEDIATED TRANSCRIPTION 65 2.08e-01 0.090200 0.81600
REACTOME PHASE 0 RAPID DEPOLARISATION 31 2.09e-01 0.130000 0.81700
REACTOME MELANIN BIOSYNTHESIS 5 2.10e-01 -0.324000 0.81800
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS 28 2.11e-01 -0.137000 0.81800
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 24 2.11e-01 0.147000 0.81800
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS 7 2.12e-01 -0.272000 0.81800
REACTOME MINERALOCORTICOID BIOSYNTHESIS 6 2.12e-01 0.294000 0.81800
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE 100 2.13e-01 0.072100 0.81800
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA 8 2.13e-01 0.254000 0.81800
REACTOME FRS MEDIATED FGFR3 SIGNALING 19 2.14e-01 0.165000 0.81800
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES 46 2.14e-01 0.106000 0.81800
REACTOME MATURATION OF PROTEIN 3A 9 2.14e-01 0.239000 0.81800
REACTOME PYROPTOSIS 27 2.15e-01 -0.138000 0.81800
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER 15 2.15e-01 0.185000 0.81800
REACTOME GPER1 SIGNALING 45 2.16e-01 0.107000 0.81800
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC 52 2.16e-01 -0.099100 0.81800
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES 49 2.19e-01 0.101000 0.82800
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS 21 2.20e-01 0.154000 0.83000
REACTOME TIE2 SIGNALING 18 2.22e-01 0.166000 0.83300
REACTOME CILIUM ASSEMBLY 190 2.22e-01 -0.051300 0.83300
REACTOME VLDL CLEARANCE 6 2.23e-01 0.287000 0.83300
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY 36 2.24e-01 0.117000 0.83400
REACTOME REPRESSION OF WNT TARGET GENES 14 2.25e-01 0.187000 0.83400
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY 7 2.25e-01 0.265000 0.83400
REACTOME MRNA SPLICING MINOR PATHWAY 49 2.25e-01 -0.100000 0.83400
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS 15 2.28e-01 -0.180000 0.83500
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 17 2.29e-01 -0.168000 0.83500
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 73 2.29e-01 0.081400 0.83500
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX 15 2.30e-01 0.179000 0.83500
REACTOME REGULATION OF RAS BY GAPS 66 2.30e-01 0.085400 0.83500
REACTOME TRYPTOPHAN CATABOLISM 14 2.30e-01 -0.185000 0.83500
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4 26 2.32e-01 0.136000 0.83500
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY 26 2.34e-01 -0.135000 0.83500
REACTOME VITAMINS 6 2.34e-01 0.280000 0.83500
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT 159 2.35e-01 0.054600 0.83500
REACTOME INTEGRIN SIGNALING 27 2.35e-01 0.132000 0.83500
REACTOME IRS MEDIATED SIGNALLING 47 2.35e-01 0.100000 0.83500
REACTOME BIOTIN TRANSPORT AND METABOLISM 10 2.35e-01 -0.217000 0.83500
REACTOME NEF MEDIATED CD4 DOWN REGULATION 9 2.35e-01 -0.228000 0.83500
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY 72 2.35e-01 0.080900 0.83500
REACTOME SARS COV 2 INFECTION 281 2.36e-01 0.041100 0.83500
REACTOME REGULATION OF BACH1 ACTIVITY 11 2.36e-01 0.207000 0.83500
REACTOME SEROTONIN RECEPTORS 11 2.36e-01 0.206000 0.83500
REACTOME NGF STIMULATED TRANSCRIPTION 38 2.36e-01 0.111000 0.83500
REACTOME GP1B IX V ACTIVATION SIGNALLING 11 2.36e-01 0.206000 0.83500
REACTOME FRS MEDIATED FGFR2 SIGNALING 24 2.37e-01 0.139000 0.83500
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM 13 2.37e-01 0.189000 0.83500
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES 7 2.38e-01 -0.257000 0.83500
REACTOME LDL CLEARANCE 19 2.39e-01 -0.156000 0.83500
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION 42 2.39e-01 0.105000 0.83500
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A 5 2.39e-01 -0.304000 0.83500
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS 21 2.40e-01 0.148000 0.83500
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS 5 2.40e-01 0.304000 0.83500
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR 19 2.40e-01 0.156000 0.83500
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS 6 2.41e-01 0.276000 0.83700
REACTOME LIGAND RECEPTOR INTERACTIONS 8 2.42e-01 0.239000 0.83700
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM 6 2.43e-01 0.275000 0.83700
REACTOME RHOA GTPASE CYCLE 142 2.43e-01 0.056700 0.83700
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION 35 2.44e-01 0.114000 0.83700
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION 10 2.45e-01 0.212000 0.83700
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE 19 2.45e-01 -0.154000 0.83700
REACTOME SIGNALING BY FGFR4 40 2.45e-01 0.106000 0.83700
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING 145 2.46e-01 0.055800 0.83700
REACTOME SEMAPHORIN INTERACTIONS 61 2.46e-01 0.085900 0.83700
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION 37 2.47e-01 0.110000 0.83700
REACTOME MITOTIC PROPHASE 134 2.47e-01 -0.057900 0.83700
REACTOME P2Y RECEPTORS 9 2.48e-01 0.222000 0.83700
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION 16 2.48e-01 0.167000 0.83700
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX 32 2.50e-01 -0.118000 0.84200
REACTOME IKBA VARIANT LEADS TO EDA ID 6 2.51e-01 -0.271000 0.84400
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN 37 2.52e-01 0.109000 0.84400
REACTOME INTERLEUKIN 9 SIGNALING 7 2.52e-01 -0.250000 0.84400
REACTOME NUCLEAR IMPORT OF REV PROTEIN 34 2.53e-01 0.113000 0.84400
REACTOME BASE EXCISION REPAIR AP SITE FORMATION 59 2.54e-01 -0.085900 0.84400
REACTOME FIBRONECTIN MATRIX FORMATION 6 2.54e-01 0.269000 0.84400
REACTOME DOPAMINE RECEPTORS 5 2.54e-01 0.294000 0.84400
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI 17 2.55e-01 0.160000 0.84400
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION 28 2.57e-01 0.124000 0.84600
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE 30 2.57e-01 0.120000 0.84600
REACTOME MEIOTIC RECOMBINATION 80 2.57e-01 -0.073300 0.84600
REACTOME REGULATION BY C FLIP 11 2.57e-01 -0.197000 0.84600
REACTOME HDMS DEMETHYLATE HISTONES 40 2.59e-01 -0.103000 0.84800
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC 198 2.60e-01 -0.046500 0.84800
REACTOME PHASE II CONJUGATION OF COMPOUNDS 102 2.60e-01 -0.064500 0.84800
REACTOME SIGNALING BY INSULIN RECEPTOR 80 2.60e-01 0.072800 0.84800
REACTOME SIGNALING BY NOTCH3 48 2.60e-01 0.093900 0.84800
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION 10 2.61e-01 0.205000 0.84800
REACTOME GASTRULATION 49 2.63e-01 0.092500 0.84800
REACTOME STABILIZATION OF P53 56 2.63e-01 0.086400 0.84800
REACTOME G ALPHA 12 13 SIGNALLING EVENTS 74 2.63e-01 0.075200 0.84800
REACTOME GLYCOLYSIS 70 2.64e-01 0.077300 0.84800
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1 46 2.64e-01 0.095100 0.84800
REACTOME AURKA ACTIVATION BY TPX2 69 2.65e-01 -0.077600 0.84800
REACTOME GLUCOSE METABOLISM 90 2.65e-01 0.068000 0.84800
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY 24 2.65e-01 0.131000 0.84800
REACTOME UCH PROTEINASES 99 2.68e-01 0.064400 0.85400
REACTOME SIGNALING BY ERYTHROPOIETIN 25 2.68e-01 0.128000 0.85400
REACTOME TRAIL SIGNALING 8 2.71e-01 -0.225000 0.86100
REACTOME MITOCHONDRIAL BIOGENESIS 87 2.72e-01 0.068200 0.86200
REACTOME PTK6 REGULATES CELL CYCLE 6 2.75e-01 0.257000 0.87000
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL 8 2.75e-01 -0.223000 0.87000
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY 25 2.77e-01 0.126000 0.87000
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION 12 2.77e-01 0.181000 0.87000
REACTOME COLLAGEN CHAIN TRIMERIZATION 42 2.78e-01 -0.096800 0.87000
REACTOME HDACS DEACETYLATE HISTONES 85 2.78e-01 -0.068100 0.87000
REACTOME CHOLESTEROL BIOSYNTHESIS 25 2.78e-01 -0.125000 0.87000
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES 7 2.79e-01 -0.236000 0.87000
REACTOME GENE SILENCING BY RNA 133 2.79e-01 -0.054300 0.87000
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES 21 2.80e-01 0.136000 0.87000
REACTOME SEMA4D IN SEMAPHORIN SIGNALING 24 2.80e-01 0.127000 0.87000
REACTOME PI3K EVENTS IN ERBB2 SIGNALING 16 2.80e-01 0.156000 0.87100
REACTOME RND1 GTPASE CYCLE 41 2.82e-01 0.097100 0.87300
REACTOME HCMV EARLY EVENTS 128 2.82e-01 -0.055000 0.87300
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 54 2.84e-01 0.084300 0.87600
REACTOME TRNA PROCESSING 105 2.85e-01 0.060400 0.87800
REACTOME CTLA4 INHIBITORY SIGNALING 21 2.87e-01 0.134000 0.87800
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES 77 2.88e-01 0.070000 0.87800
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1 9 2.89e-01 0.204000 0.87800
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7 7 2.89e-01 0.231000 0.87800
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS 5 2.90e-01 0.273000 0.87800
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS 11 2.90e-01 -0.184000 0.87800
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 41 2.90e-01 0.095500 0.87800
REACTOME BASIGIN INTERACTIONS 24 2.91e-01 0.125000 0.87800
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION 31 2.91e-01 0.110000 0.87800
REACTOME RHOD GTPASE CYCLE 49 2.92e-01 0.087100 0.87800
REACTOME INTERLEUKIN 20 FAMILY SIGNALING 25 2.92e-01 -0.122000 0.87800
REACTOME SHC MEDIATED CASCADE FGFR3 17 2.92e-01 0.148000 0.87800
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT 6 2.92e-01 0.248000 0.87800
REACTOME MET ACTIVATES PTK2 SIGNALING 30 2.93e-01 -0.111000 0.87800
REACTOME NEF AND SIGNAL TRANSDUCTION 8 2.93e-01 0.215000 0.87800
REACTOME IRS ACTIVATION 5 2.94e-01 -0.271000 0.87900
REACTOME FRS MEDIATED FGFR1 SIGNALING 23 2.96e-01 0.126000 0.87900
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION 5 2.96e-01 0.270000 0.87900
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5 7 2.96e-01 -0.228000 0.87900
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2 77 2.97e-01 0.068700 0.87900
REACTOME PCP CE PATHWAY 91 2.97e-01 0.063200 0.87900
REACTOME G ALPHA Q SIGNALLING EVENTS 206 2.98e-01 0.042100 0.87900
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS 139 2.99e-01 0.051000 0.87900
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS 26 3.00e-01 0.117000 0.87900
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY 23 3.00e-01 -0.125000 0.87900
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES 16 3.00e-01 0.150000 0.87900
REACTOME MEIOTIC SYNAPSIS 73 3.01e-01 -0.070000 0.87900
REACTOME TBC RABGAPS 40 3.01e-01 -0.094400 0.87900
REACTOME CHYLOMICRON CLEARANCE 5 3.01e-01 -0.267000 0.87900
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE 7 3.01e-01 0.226000 0.87900
REACTOME PTK6 PROMOTES HIF1A STABILIZATION 6 3.02e-01 0.243000 0.87900
REACTOME ACTIVATION OF RAS IN B CELLS 5 3.02e-01 -0.266000 0.87900
REACTOME SIGNALING BY TGFB FAMILY MEMBERS 119 3.03e-01 0.054600 0.87900
REACTOME NUCLEAR ENVELOPE BREAKDOWN 52 3.04e-01 0.082400 0.87900
REACTOME SIGNALING BY WNT IN CANCER 32 3.04e-01 0.105000 0.87900
REACTOME RAF ACTIVATION 33 3.05e-01 -0.103000 0.88100
REACTOME INTERLEUKIN 2 FAMILY SIGNALING 40 3.07e-01 0.093400 0.88300
REACTOME ASPIRIN ADME 42 3.07e-01 -0.091100 0.88300
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE 39 3.08e-01 -0.094400 0.88400
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY 15 3.08e-01 -0.152000 0.88400
REACTOME SENSORY PROCESSING OF SOUND 72 3.11e-01 0.069100 0.88500
REACTOME ATTACHMENT AND ENTRY 16 3.11e-01 -0.146000 0.88500
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS 11 3.11e-01 0.176000 0.88500
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION 29 3.12e-01 -0.109000 0.88500
REACTOME METABOLISM OF POLYAMINES 56 3.13e-01 0.078000 0.88500
REACTOME JOSEPHIN DOMAIN DUBS 11 3.13e-01 0.176000 0.88500
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE 49 3.14e-01 0.083100 0.88500
REACTOME BILE ACID AND BILE SALT METABOLISM 45 3.15e-01 0.086600 0.88500
REACTOME BETA DEFENSINS 27 3.15e-01 -0.112000 0.88500
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS 100 3.16e-01 0.058000 0.88500
REACTOME DEGRADATION OF AXIN 54 3.17e-01 0.078800 0.88500
REACTOME HIV ELONGATION ARREST AND RECOVERY 33 3.17e-01 -0.101000 0.88500
REACTOME ABACAVIR ADME 9 3.17e-01 -0.193000 0.88500
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3 679 3.18e-01 0.022500 0.88500
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING 16 3.18e-01 0.144000 0.88500
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT 152 3.18e-01 -0.046900 0.88500
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE 76 3.18e-01 -0.066200 0.88500
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER 8 3.19e-01 0.204000 0.88500
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE 74 3.19e-01 0.066900 0.88600
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES 29 3.21e-01 0.106000 0.88700
REACTOME UNWINDING OF DNA 12 3.21e-01 0.165000 0.88700
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM 9 3.23e-01 -0.190000 0.88700
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS 21 3.23e-01 -0.125000 0.88700
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION 138 3.23e-01 -0.048700 0.88700
REACTOME DISEASES OF DNA REPAIR 51 3.24e-01 0.079900 0.88700
REACTOME NEF MEDIATED CD8 DOWN REGULATION 7 3.24e-01 -0.215000 0.88700
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY 54 3.24e-01 0.077500 0.88700
REACTOME PHOSPHORYLATION OF THE APC C 20 3.25e-01 0.127000 0.88700
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE 20 3.26e-01 -0.127000 0.88900
REACTOME BETA OXIDATION OF PRISTANOYL COA 9 3.27e-01 -0.189000 0.89000
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS 27 3.29e-01 0.109000 0.89000
REACTOME G PROTEIN BETA GAMMA SIGNALLING 30 3.29e-01 0.103000 0.89000
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER 7 3.30e-01 0.213000 0.89000
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS 63 3.30e-01 0.070900 0.89000
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN 5 3.30e-01 -0.251000 0.89000
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING 22 3.30e-01 0.120000 0.89000
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS 21 3.31e-01 0.122000 0.89000
REACTOME REGULATION OF PTEN LOCALIZATION 8 3.31e-01 0.198000 0.89000
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS 30 3.33e-01 0.102000 0.89000
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION 6 3.35e-01 0.227000 0.89000
REACTOME DEVELOPMENTAL BIOLOGY 1115 3.36e-01 0.017100 0.89000
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS 11 3.36e-01 -0.167000 0.89000
REACTOME DOWNREGULATION OF ERBB2 SIGNALING 29 3.36e-01 0.103000 0.89000
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM 78 3.37e-01 -0.062900 0.89000
REACTOME CELL CELL JUNCTION ORGANIZATION 64 3.37e-01 -0.069400 0.89000
REACTOME CA2 PATHWAY 62 3.38e-01 0.070400 0.89000
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE 24 3.38e-01 0.113000 0.89000
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION 5 3.39e-01 0.247000 0.89000
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON 17 3.40e-01 0.134000 0.89000
REACTOME PI METABOLISM 79 3.40e-01 0.062000 0.89000
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS 35 3.41e-01 0.093100 0.89000
REACTOME RIBAVIRIN ADME 11 3.42e-01 0.166000 0.89000
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING 6 3.42e-01 0.224000 0.89000
REACTOME INTEGRIN CELL SURFACE INTERACTIONS 83 3.42e-01 -0.060300 0.89000
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN 19 3.43e-01 -0.126000 0.89000
REACTOME EGFR TRANSACTIVATION BY GASTRIN 9 3.44e-01 -0.182000 0.89000
REACTOME RECYCLING OF BILE ACIDS AND SALTS 18 3.44e-01 0.129000 0.89000
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE 9 3.44e-01 0.182000 0.89000
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION 21 3.45e-01 -0.119000 0.89000
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX 14 3.45e-01 0.146000 0.89000
REACTOME AMINO ACIDS REGULATE MTORC1 53 3.47e-01 -0.074700 0.89000
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS 55 3.47e-01 -0.073300 0.89000
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS 100 3.47e-01 -0.054400 0.89000
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10 12 3.47e-01 -0.157000 0.89000
REACTOME PROCESSING OF INTRONLESS PRE MRNAS 19 3.47e-01 0.125000 0.89000
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE 93 3.47e-01 -0.056400 0.89000
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE 43 3.47e-01 0.082800 0.89000
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT 23 3.48e-01 -0.113000 0.89000
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING 67 3.49e-01 0.066200 0.89100
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP 104 3.49e-01 -0.053100 0.89100
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG 5 3.50e-01 -0.241000 0.89100
REACTOME ORGANIC ANION TRANSPORTERS 10 3.51e-01 0.170000 0.89100
REACTOME SIGNALING BY CSF3 G CSF 30 3.52e-01 0.098300 0.89100
REACTOME RHO GTPASES ACTIVATE PAKS 19 3.52e-01 -0.123000 0.89100
REACTOME NADE MODULATES DEATH SIGNALLING 5 3.52e-01 -0.240000 0.89100
REACTOME RND2 GTPASE CYCLE 42 3.53e-01 0.082900 0.89100
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 22 3.53e-01 0.114000 0.89100
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA 28 3.54e-01 0.101000 0.89300
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 81 3.55e-01 0.059400 0.89500
REACTOME ARACHIDONIC ACID METABOLISM 57 3.57e-01 0.070500 0.89600
REACTOME DNA REPAIR 321 3.57e-01 -0.029900 0.89600
REACTOME CRISTAE FORMATION 27 3.57e-01 0.102000 0.89600
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING 6 3.59e-01 0.216000 0.89700
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE 5 3.60e-01 -0.237000 0.89700
REACTOME CELL CYCLE MITOTIC 539 3.60e-01 -0.023100 0.89700
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX 10 3.61e-01 0.167000 0.89700
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2 117 3.61e-01 0.048900 0.89700
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9 7 3.62e-01 0.199000 0.89700
REACTOME FATTY ACIDS 15 3.62e-01 0.136000 0.89700
REACTOME HIV LIFE CYCLE 145 3.62e-01 0.043800 0.89700
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING 25 3.63e-01 -0.105000 0.89800
REACTOME SIGNALING BY NTRKS 132 3.65e-01 0.045700 0.90000
REACTOME CIRCADIAN CLOCK 68 3.65e-01 0.063500 0.90000
REACTOME AMINE LIGAND BINDING RECEPTORS 40 3.67e-01 0.082400 0.90300
REACTOME SIGNALLING TO RAS 20 3.68e-01 -0.116000 0.90300
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING 13 3.68e-01 0.144000 0.90300
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS 7 3.70e-01 0.196000 0.90400
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS 9 3.71e-01 0.172000 0.90400
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES 29 3.72e-01 0.095900 0.90400
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION 160 3.74e-01 -0.040700 0.90400
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY 25 3.75e-01 -0.102000 0.90400
REACTOME RESOLUTION OF SISTER CHROMATID COHESION 120 3.77e-01 -0.046700 0.90400
REACTOME TRIGLYCERIDE BIOSYNTHESIS 12 3.78e-01 -0.147000 0.90400
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY 6 3.78e-01 -0.208000 0.90400
REACTOME TELOMERE MAINTENANCE 106 3.78e-01 -0.049500 0.90400
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA 5 3.79e-01 0.227000 0.90400
REACTOME HYDROLYSIS OF LPC 9 3.79e-01 0.169000 0.90400
REACTOME SPRY REGULATION OF FGF SIGNALING 16 3.79e-01 0.127000 0.90400
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS 11 3.80e-01 -0.153000 0.90400
REACTOME FORMATION OF INCISION COMPLEX IN GG NER 40 3.80e-01 0.080300 0.90400
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX 57 3.80e-01 -0.067200 0.90400
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE 48 3.80e-01 0.073200 0.90400
REACTOME DNA STRAND ELONGATION 31 3.81e-01 0.091000 0.90400
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY 16 3.81e-01 0.126000 0.90400
REACTOME RESPIRATORY ELECTRON TRANSPORT 90 3.82e-01 0.053300 0.90400
REACTOME GERM LAYER FORMATION AT GASTRULATION 17 3.83e-01 0.122000 0.90400
REACTOME RAC2 GTPASE CYCLE 81 3.84e-01 0.055900 0.90400
REACTOME DEFECTIVE GALNT3 CAUSES HFTC 16 3.86e-01 -0.125000 0.90400
REACTOME ASSEMBLY OF THE HIV VIRION 16 3.86e-01 0.125000 0.90400
REACTOME SUMOYLATION OF RNA BINDING PROTEINS 47 3.87e-01 0.072900 0.90400
REACTOME ERKS ARE INACTIVATED 13 3.88e-01 0.138000 0.90400
REACTOME HS GAG BIOSYNTHESIS 28 3.88e-01 -0.094200 0.90400
REACTOME HEDGEHOG ON STATE 85 3.89e-01 0.054000 0.90400
REACTOME SHC MEDIATED CASCADE FGFR1 21 3.90e-01 0.108000 0.90400
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION 32 3.91e-01 0.087700 0.90400
REACTOME FLT3 SIGNALING IN DISEASE 28 3.91e-01 0.093700 0.90400
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS 5 3.92e-01 0.221000 0.90400
REACTOME SIGNALING BY PDGF 57 3.93e-01 -0.065400 0.90400
REACTOME STIMULI SENSING CHANNELS 100 3.93e-01 -0.049400 0.90400
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION 84 3.95e-01 -0.053700 0.90400
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 29 3.95e-01 0.091300 0.90400
REACTOME PROTEIN METHYLATION 17 3.95e-01 0.119000 0.90400
REACTOME SIGNALING BY NOTCH 234 3.96e-01 0.032200 0.90400
REACTOME DISEASES OF BASE EXCISION REPAIR 5 3.98e-01 0.218000 0.90400
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS 91 3.99e-01 -0.051200 0.90400
REACTOME ORGANIC CATION TRANSPORT 10 3.99e-01 -0.154000 0.90400
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS 37 3.99e-01 0.080100 0.90400
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION 49 3.99e-01 -0.069600 0.90400
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 53 4.00e-01 0.066900 0.90400
REACTOME O LINKED GLYCOSYLATION 109 4.00e-01 -0.046700 0.90400
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES 21 4.00e-01 -0.106000 0.90400
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX 91 4.01e-01 0.051000 0.90400
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION 19 4.01e-01 0.111000 0.90400
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT 101 4.01e-01 -0.048300 0.90400
REACTOME INTERLEUKIN 2 SIGNALING 11 4.03e-01 0.146000 0.90400
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS 35 4.04e-01 0.081600 0.90400
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX 19 4.04e-01 0.111000 0.90400
REACTOME MYD88 INDEPENDENT TLR4 CASCADE 103 4.05e-01 0.047500 0.90400
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION 183 4.05e-01 -0.035700 0.90400
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY 30 4.06e-01 0.087700 0.90400
REACTOME METALLOPROTEASE DUBS 36 4.06e-01 -0.080100 0.90400
REACTOME NEURONAL SYSTEM 388 4.06e-01 -0.024600 0.90400
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE 15 4.06e-01 0.124000 0.90400
REACTOME SIGNALING BY EGFR 49 4.06e-01 0.068500 0.90400
REACTOME SIGNALING BY FGFR2 IN DISEASE 42 4.07e-01 0.074000 0.90400
REACTOME CELLULAR HEXOSE TRANSPORT 21 4.07e-01 -0.104000 0.90400
REACTOME ENDOSOMAL VACUOLAR PATHWAY 11 4.07e-01 -0.144000 0.90400
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5 6 4.08e-01 0.195000 0.90400
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT 5 4.08e-01 -0.214000 0.90400
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS 52 4.08e-01 0.066300 0.90400
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX 29 4.09e-01 0.088600 0.90400
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES 12 4.11e-01 -0.137000 0.90400
REACTOME CYTOSOLIC TRNA AMINOACYLATION 22 4.11e-01 -0.101000 0.90400
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 361 4.11e-01 -0.025200 0.90400
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS 9 4.11e-01 -0.158000 0.90400
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE 20 4.12e-01 0.106000 0.90400
REACTOME INTERLEUKIN 17 SIGNALING 66 4.12e-01 0.058300 0.90400
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS 62 4.13e-01 -0.060100 0.90400
REACTOME REGULATION OF INSULIN SECRETION 77 4.14e-01 0.053900 0.90400
REACTOME NUCLEOTIDE BIOSYNTHESIS 14 4.14e-01 0.126000 0.90400
REACTOME MITOTIC TELOPHASE CYTOKINESIS 11 4.14e-01 0.142000 0.90400
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS 32 4.14e-01 -0.083400 0.90400
REACTOME METALLOTHIONEINS BIND METALS 11 4.15e-01 0.142000 0.90400
REACTOME UREA CYCLE 9 4.15e-01 0.157000 0.90400
REACTOME DOWNREGULATION OF ERBB4 SIGNALING 9 4.16e-01 0.157000 0.90400
REACTOME VXPX CARGO TARGETING TO CILIUM 20 4.17e-01 -0.105000 0.90400
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES 65 4.17e-01 -0.058200 0.90400
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION 20 4.18e-01 0.105000 0.90400
REACTOME METABOLISM OF STEROID HORMONES 35 4.18e-01 -0.079100 0.90400
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS 17 4.19e-01 -0.113000 0.90400
REACTOME PTEN REGULATION 135 4.19e-01 0.040300 0.90400
REACTOME SIGNAL ATTENUATION 10 4.19e-01 -0.147000 0.90400
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING 127 4.20e-01 0.041500 0.90400
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS 87 4.20e-01 -0.050000 0.90400
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS 11 4.21e-01 0.140000 0.90400
REACTOME DNA REPLICATION INITIATION 7 4.21e-01 0.176000 0.90400
REACTOME RUNX3 REGULATES NOTCH SIGNALING 13 4.21e-01 0.129000 0.90400
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION 59 4.22e-01 0.060400 0.90400
REACTOME SIGNALING BY NTRK2 TRKB 25 4.22e-01 0.092800 0.90400
REACTOME METAL ION SLC TRANSPORTERS 23 4.23e-01 -0.096600 0.90400
REACTOME RHO GTPASES ACTIVATE FORMINS 136 4.23e-01 -0.039800 0.90400
REACTOME STAT5 ACTIVATION 7 4.23e-01 0.175000 0.90400
REACTOME COBALAMIN CBL METABOLISM 7 4.23e-01 0.175000 0.90400
REACTOME INTERLEUKIN 15 SIGNALING 13 4.24e-01 0.128000 0.90400
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA 5 4.24e-01 0.206000 0.90400
REACTOME LAMININ INTERACTIONS 28 4.24e-01 -0.087200 0.90400
REACTOME TRNA PROCESSING IN THE NUCLEUS 58 4.25e-01 0.060600 0.90400
REACTOME SYNTHESIS OF LIPOXINS LX 6 4.25e-01 0.188000 0.90400
REACTOME PROCESSING AND ACTIVATION OF SUMO 10 4.25e-01 0.146000 0.90400
REACTOME TRANSCRIPTIONAL REGULATION BY TP53 351 4.26e-01 0.024700 0.90400
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS 60 4.26e-01 0.059400 0.90400
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES 14 4.27e-01 -0.123000 0.90400
REACTOME TRP CHANNELS 27 4.28e-01 -0.088200 0.90500
REACTOME SYNTHESIS OF GDP MANNOSE 5 4.28e-01 -0.204000 0.90500
REACTOME SIGNALING BY NTRK3 TRKC 17 4.30e-01 -0.111000 0.90600
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION 20 4.31e-01 0.102000 0.90600
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION 22 4.31e-01 0.097000 0.90600
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS 8 4.32e-01 -0.160000 0.90600
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING 61 4.33e-01 0.058000 0.90600
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS 46 4.34e-01 0.066700 0.90600
REACTOME SCAVENGING BY CLASS B RECEPTORS 6 4.34e-01 0.184000 0.90600
REACTOME RNA POLYMERASE I PROMOTER ESCAPE 83 4.35e-01 -0.049600 0.90600
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING 29 4.35e-01 0.083700 0.90600
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING 23 4.36e-01 0.093800 0.90600
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 28 4.37e-01 -0.084900 0.90600
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY 10 4.37e-01 0.142000 0.90600
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB 5 4.37e-01 0.201000 0.90600
REACTOME TRANSLESION SYNTHESIS BY POLK 17 4.37e-01 0.109000 0.90600
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS 7 4.38e-01 0.169000 0.90600
REACTOME PI3K EVENTS IN ERBB4 SIGNALING 10 4.40e-01 0.141000 0.90600
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN 45 4.40e-01 -0.066600 0.90600
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL 8 4.40e-01 0.158000 0.90600
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION 21 4.43e-01 -0.096800 0.90600
REACTOME INTERLEUKIN 21 SIGNALING 9 4.43e-01 -0.148000 0.90600
REACTOME RECYCLING OF EIF2 GDP 7 4.43e-01 0.167000 0.90600
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR 11 4.45e-01 0.133000 0.90600
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION 12 4.45e-01 0.127000 0.90600
REACTOME TRIGLYCERIDE METABOLISM 35 4.45e-01 0.074600 0.90600
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT 77 4.45e-01 0.050300 0.90600
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1 5 4.45e-01 0.197000 0.90600
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS 43 4.47e-01 -0.067100 0.90600
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC 21 4.48e-01 0.095600 0.90600
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM 21 4.48e-01 0.095600 0.90600
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD 5 4.49e-01 -0.195000 0.90600
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS 15 4.49e-01 0.113000 0.90600
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS 17 4.49e-01 0.106000 0.90600
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN 5 4.49e-01 0.195000 0.90600
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K 6 4.49e-01 -0.178000 0.90600
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN 35 4.50e-01 0.073900 0.90600
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION 62 4.50e-01 -0.055500 0.90600
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS 15 4.50e-01 0.113000 0.90600
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE 15 4.50e-01 -0.113000 0.90600
REACTOME ERK MAPK TARGETS 20 4.51e-01 0.097400 0.90600
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION 18 4.51e-01 0.103000 0.90600
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III 31 4.52e-01 -0.078100 0.90600
REACTOME PEPTIDE HORMONE METABOLISM 84 4.52e-01 0.047400 0.90600
REACTOME ACYL CHAIN REMODELLING OF PS 22 4.54e-01 0.092300 0.90600
REACTOME PURINE SALVAGE 12 4.54e-01 0.125000 0.90600
REACTOME NTRK2 ACTIVATES RAC1 5 4.54e-01 0.193000 0.90600
REACTOME PROTEIN LOCALIZATION 153 4.56e-01 0.034900 0.90600
REACTOME SELECTIVE AUTOPHAGY 79 4.56e-01 -0.048500 0.90600
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA 11 4.56e-01 -0.130000 0.90600
REACTOME SCAVENGING BY CLASS F RECEPTORS 6 4.57e-01 -0.175000 0.90600
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR 66 4.57e-01 0.052900 0.90600
REACTOME ASPARAGINE N LINKED GLYCOSYLATION 299 4.57e-01 -0.025000 0.90600
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM 11 4.58e-01 0.129000 0.90600
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF 17 4.59e-01 0.104000 0.90600
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS 17 4.59e-01 0.104000 0.90600
REACTOME PREDNISONE ADME 10 4.60e-01 0.135000 0.90600
REACTOME HORMONE LIGAND BINDING RECEPTORS 12 4.60e-01 -0.123000 0.90600
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL 12 4.60e-01 0.123000 0.90600
REACTOME HEME BIOSYNTHESIS 13 4.61e-01 -0.118000 0.90600
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION 13 4.61e-01 0.118000 0.90600
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE 7 4.62e-01 0.161000 0.90600
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION 13 4.64e-01 0.117000 0.90900
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION 36 4.65e-01 0.070400 0.90900
REACTOME CELLULAR SENESCENCE 189 4.65e-01 -0.030800 0.90900
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING 25 4.66e-01 0.084200 0.90900
REACTOME DISEASES OF METABOLISM 237 4.66e-01 -0.027500 0.90900
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION 20 4.68e-01 0.093800 0.90900
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES 17 4.68e-01 -0.102000 0.90900
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES 59 4.68e-01 -0.054600 0.90900
REACTOME CREATION OF C4 AND C2 ACTIVATORS 14 4.69e-01 -0.112000 0.90900
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS 9 4.69e-01 -0.139000 0.90900
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS 6 4.70e-01 0.170000 0.90900
REACTOME CHROMOSOME MAINTENANCE 130 4.70e-01 -0.036700 0.90900
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN 13 4.71e-01 -0.116000 0.90900
REACTOME SURFACTANT METABOLISM 28 4.71e-01 -0.078700 0.90900
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR 7 4.73e-01 -0.157000 0.91100
REACTOME RHOBTB1 GTPASE CYCLE 22 4.73e-01 -0.088300 0.91100
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES 78 4.74e-01 -0.046900 0.91200
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES 11 4.77e-01 0.124000 0.91700
REACTOME COENZYME A BIOSYNTHESIS 8 4.78e-01 0.145000 0.91700
REACTOME HCMV INFECTION 152 4.79e-01 -0.033300 0.91700
REACTOME ACTIVATION OF TRKA RECEPTORS 6 4.80e-01 -0.166000 0.91800
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION 193 4.81e-01 -0.029400 0.91800
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN 76 4.81e-01 -0.046800 0.91800
REACTOME DISEASES OF MITOTIC CELL CYCLE 37 4.82e-01 0.066800 0.91800
REACTOME ONCOGENE INDUCED SENESCENCE 35 4.82e-01 0.068600 0.91800
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS 46 4.83e-01 -0.059800 0.91800
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY 8 4.83e-01 -0.143000 0.91800
REACTOME SIGNALING BY ERBB4 57 4.83e-01 -0.053700 0.91800
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION 8 4.88e-01 0.142000 0.92100
REACTOME ABC TRANSPORTER DISORDERS 76 4.88e-01 0.046000 0.92100
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS 5 4.88e-01 0.179000 0.92100
REACTOME DISEASES OF CARBOHYDRATE METABOLISM 31 4.89e-01 -0.071900 0.92100
REACTOME CELLULAR RESPONSE TO HYPOXIA 74 4.89e-01 0.046500 0.92100
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS 5 4.90e-01 -0.178000 0.92100
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND 14 4.90e-01 0.107000 0.92100
REACTOME APOPTOSIS 173 4.90e-01 0.030400 0.92100
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA 36 4.90e-01 0.066500 0.92100
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS 74 4.91e-01 0.046300 0.92100
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE 35 4.93e-01 0.067000 0.92200
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT 7 4.93e-01 0.150000 0.92200
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN 32 4.95e-01 0.069800 0.92200
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT 99 4.95e-01 0.039700 0.92200
REACTOME G PROTEIN MEDIATED EVENTS 53 4.96e-01 0.054100 0.92200
REACTOME POLO LIKE KINASE MEDIATED EVENTS 16 4.97e-01 0.098100 0.92200
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC 28 4.97e-01 -0.074200 0.92200
REACTOME REGULATED PROTEOLYSIS OF P75NTR 11 4.97e-01 -0.118000 0.92200
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE 10 4.98e-01 0.124000 0.92200
REACTOME INTERLEUKIN 6 FAMILY SIGNALING 24 4.98e-01 -0.079800 0.92200
REACTOME ALPHA OXIDATION OF PHYTANATE 6 4.99e-01 -0.159000 0.92200
REACTOME PROCESSING OF SMDT1 16 5.00e-01 -0.097500 0.92200
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION 15 5.00e-01 0.101000 0.92200
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION 9 5.00e-01 0.130000 0.92200
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA 17 5.01e-01 0.094400 0.92200
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM 13 5.01e-01 0.108000 0.92200
REACTOME C TYPE LECTIN RECEPTORS CLRS 136 5.02e-01 -0.033400 0.92200
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 89 5.04e-01 0.041000 0.92200
REACTOME BIOSYNTHESIS OF MARESINS 8 5.04e-01 0.137000 0.92200
REACTOME REPRODUCTION 136 5.04e-01 -0.033200 0.92200
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION 84 5.04e-01 -0.042100 0.92200
REACTOME PLATELET SENSITIZATION BY LDL 17 5.05e-01 -0.093400 0.92200
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4 33 5.06e-01 -0.067000 0.92200
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS 45 5.06e-01 0.057300 0.92200
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2 13 5.06e-01 -0.107000 0.92200
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS 16 5.06e-01 -0.095900 0.92200
REACTOME NUCLEOTIDE CATABOLISM 35 5.07e-01 -0.064700 0.92200
REACTOME FCERI MEDIATED NF KB ACTIVATION 78 5.09e-01 0.043300 0.92200
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES 80 5.09e-01 0.042700 0.92200
REACTOME COLLAGEN FORMATION 88 5.09e-01 -0.040700 0.92200
REACTOME DNA DAMAGE BYPASS 47 5.11e-01 -0.055400 0.92200
REACTOME ELASTIC FIBRE FORMATION 44 5.11e-01 0.057300 0.92200
REACTOME GABA B RECEPTOR ACTIVATION 43 5.11e-01 0.057900 0.92200
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND 9 5.12e-01 -0.126000 0.92200
REACTOME ESR MEDIATED SIGNALING 210 5.12e-01 -0.026200 0.92200
REACTOME SIGNALING BY EGFR IN CANCER 25 5.13e-01 0.075700 0.92200
REACTOME INTERLEUKIN 37 SIGNALING 20 5.13e-01 0.084500 0.92200
REACTOME DEFECTS IN BIOTIN BTN METABOLISM 8 5.13e-01 -0.133000 0.92200
REACTOME INTERFERON GAMMA SIGNALING 88 5.15e-01 -0.040200 0.92200
REACTOME SIGNALING BY ALK IN CANCER 53 5.15e-01 0.051700 0.92200
REACTOME GLUCOCORTICOID BIOSYNTHESIS 10 5.15e-01 0.119000 0.92200
REACTOME RAB REGULATION OF TRAFFICKING 110 5.15e-01 -0.035900 0.92200
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS 43 5.17e-01 0.057100 0.92400
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2 8 5.17e-01 0.132000 0.92400
REACTOME MHC CLASS II ANTIGEN PRESENTATION 121 5.19e-01 -0.034000 0.92400
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION 14 5.19e-01 0.099700 0.92400
REACTOME PTK6 EXPRESSION 5 5.19e-01 0.167000 0.92400
REACTOME SIGNALING BY HIPPO 19 5.21e-01 -0.085100 0.92500
REACTOME RHOB GTPASE CYCLE 67 5.21e-01 0.045300 0.92500
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS 46 5.21e-01 0.054700 0.92500
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION 8 5.24e-01 -0.130000 0.92600
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION 19 5.24e-01 0.084500 0.92600
REACTOME CARNITINE METABOLISM 13 5.24e-01 -0.102000 0.92600
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY 29 5.24e-01 0.068300 0.92600
REACTOME PI5P REGULATES TP53 ACETYLATION 9 5.26e-01 -0.122000 0.92600
REACTOME PLASMA LIPOPROTEIN CLEARANCE 37 5.26e-01 0.060200 0.92600
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS 8 5.26e-01 0.129000 0.92600
REACTOME OTHER INTERLEUKIN SIGNALING 24 5.27e-01 0.074600 0.92600
REACTOME MAP2K AND MAPK ACTIVATION 38 5.27e-01 -0.059300 0.92600
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS 14 5.28e-01 -0.097500 0.92600
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION 41 5.28e-01 0.057000 0.92600
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS 6 5.31e-01 -0.148000 0.92600
REACTOME SODIUM PROTON EXCHANGERS 7 5.32e-01 0.136000 0.92600
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM 38 5.32e-01 0.058600 0.92600
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS 34 5.32e-01 0.061900 0.92600
REACTOME TRANSPORT AND SYNTHESIS OF PAPS 6 5.33e-01 -0.147000 0.92600
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH 6 5.34e-01 -0.147000 0.92600
REACTOME METABOLISM OF CARBOHYDRATES 279 5.34e-01 0.021600 0.92600
REACTOME THE PHOTOTRANSDUCTION CASCADE 32 5.35e-01 -0.063300 0.92600
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION 7 5.35e-01 -0.135000 0.92600
REACTOME REGULATION OF NF KAPPA B SIGNALING 17 5.36e-01 0.086800 0.92600
REACTOME REGULATED NECROSIS 57 5.36e-01 -0.047400 0.92600
REACTOME ACYL CHAIN REMODELLING OF PC 27 5.36e-01 0.068800 0.92600
REACTOME PEROXISOMAL LIPID METABOLISM 28 5.36e-01 -0.067600 0.92600
REACTOME KERATAN SULFATE DEGRADATION 13 5.36e-01 0.099100 0.92600
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND 16 5.38e-01 -0.088900 0.92600
REACTOME EARLY PHASE OF HIV LIFE CYCLE 14 5.39e-01 0.094900 0.92600
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE 12 5.39e-01 -0.102000 0.92600
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL 14 5.40e-01 0.094500 0.92600
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE 15 5.41e-01 0.091100 0.92600
REACTOME GLUCONEOGENESIS 33 5.41e-01 0.061400 0.92600
REACTOME DUAL INCISION IN TC NER 63 5.41e-01 -0.044500 0.92600
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE 7 5.43e-01 0.133000 0.92600
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 5.43e-01 0.090700 0.92600
REACTOME FORMATION OF APOPTOSOME 10 5.44e-01 -0.111000 0.92600
REACTOME PEPTIDE LIGAND BINDING RECEPTORS 188 5.44e-01 -0.025700 0.92600
REACTOME MEIOSIS 110 5.44e-01 -0.033500 0.92600
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT 31 5.44e-01 0.062900 0.92600
REACTOME NRAGE SIGNALS DEATH THROUGH JNK 53 5.46e-01 0.048000 0.92600
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL 15 5.46e-01 -0.090100 0.92600
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES 118 5.46e-01 0.032100 0.92600
REACTOME TRAF6 MEDIATED NF KB ACTIVATION 24 5.47e-01 0.071000 0.92600
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION 22 5.48e-01 0.073900 0.92600
REACTOME LONG TERM POTENTIATION 22 5.49e-01 0.073800 0.92600
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT 222 5.50e-01 0.023300 0.92600
REACTOME PYRIMIDINE SALVAGE 10 5.50e-01 -0.109000 0.92600
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION 10 5.51e-01 0.109000 0.92600
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION 20 5.51e-01 0.077000 0.92600
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE 20 5.52e-01 0.076900 0.92600
REACTOME FGFR2 ALTERNATIVE SPLICING 27 5.52e-01 0.066100 0.92600
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING 23 5.52e-01 -0.071600 0.92600
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE 5 5.52e-01 0.154000 0.92600
REACTOME FRS MEDIATED FGFR4 SIGNALING 21 5.53e-01 0.074800 0.92600
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS 9 5.53e-01 -0.114000 0.92600
REACTOME CELL JUNCTION ORGANIZATION 89 5.54e-01 -0.036300 0.92600
REACTOME DISEASES OF GLYCOSYLATION 137 5.54e-01 -0.029200 0.92600
REACTOME PROGRAMMED CELL DEATH 204 5.56e-01 0.023900 0.92600
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL 14 5.56e-01 -0.090900 0.92600
REACTOME SUPPRESSION OF APOPTOSIS 7 5.56e-01 -0.128000 0.92600
REACTOME SIGNALING BY FGFR1 IN DISEASE 38 5.56e-01 0.055100 0.92600
REACTOME NUCLEAR SIGNALING BY ERBB4 32 5.57e-01 -0.060000 0.92600
REACTOME SNRNP ASSEMBLY 53 5.59e-01 0.046500 0.92600
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS 9 5.59e-01 -0.113000 0.92600
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS 188 5.59e-01 0.024700 0.92600
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING 25 5.60e-01 0.067400 0.92600
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B 7 5.60e-01 0.127000 0.92600
REACTOME MTORC1 MEDIATED SIGNALLING 23 5.61e-01 -0.070000 0.92600
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA 37 5.61e-01 0.055200 0.92600
REACTOME FATTY ACID METABOLISM 170 5.61e-01 0.025800 0.92600
REACTOME ERBB2 REGULATES CELL MOTILITY 15 5.62e-01 0.086500 0.92600
REACTOME DAG AND IP3 SIGNALING 40 5.62e-01 0.052900 0.92600
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION 6 5.63e-01 -0.136000 0.92600
REACTOME RND3 GTPASE CYCLE 41 5.63e-01 0.052200 0.92600
REACTOME PEROXISOMAL PROTEIN IMPORT 62 5.64e-01 0.042400 0.92700
REACTOME G1 S SPECIFIC TRANSCRIPTION 28 5.67e-01 0.062500 0.92900
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6 32 5.67e-01 0.058400 0.92900
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE 5 5.69e-01 0.147000 0.92900
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING 14 5.69e-01 -0.088000 0.92900
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS 16 5.69e-01 0.082200 0.92900
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA 9 5.70e-01 -0.109000 0.92900
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION 15 5.70e-01 0.084700 0.92900
REACTOME ERYTHROPOIETIN ACTIVATES RAS 14 5.72e-01 0.087100 0.92900
REACTOME DNA DAMAGE REVERSAL 8 5.73e-01 -0.115000 0.92900
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND 55 5.73e-01 -0.044000 0.92900
REACTOME NONCANONICAL ACTIVATION OF NOTCH3 8 5.73e-01 -0.115000 0.92900
REACTOME VIRAL MESSENGER RNA SYNTHESIS 44 5.73e-01 0.049100 0.92900
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION 23 5.73e-01 -0.067800 0.92900
REACTOME WNT MEDIATED ACTIVATION OF DVL 8 5.74e-01 -0.115000 0.92900
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY 5 5.74e-01 0.145000 0.92900
REACTOME TRAFFICKING OF AMPA RECEPTORS 29 5.75e-01 -0.060100 0.92900
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION 8 5.77e-01 -0.114000 0.92900
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS 43 5.77e-01 0.049100 0.92900
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS 9 5.77e-01 -0.107000 0.92900
REACTOME LDL REMODELING 6 5.78e-01 -0.131000 0.92900
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS 312 5.78e-01 0.018300 0.92900
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION 11 5.78e-01 -0.096900 0.92900
REACTOME MTOR SIGNALLING 40 5.79e-01 -0.050700 0.92900
REACTOME TRANSLESION SYNTHESIS BY POLH 19 5.79e-01 0.073400 0.92900
REACTOME MITOCHONDRIAL PROTEIN IMPORT 58 5.80e-01 0.042000 0.92900
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION 32 5.81e-01 0.056400 0.92900
REACTOME ARMS MEDIATED ACTIVATION 7 5.81e-01 -0.120000 0.92900
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING 13 5.81e-01 0.088300 0.92900
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX 36 5.82e-01 0.053000 0.92900
REACTOME DNA DAMAGE RECOGNITION IN GG NER 36 5.82e-01 0.053000 0.92900
REACTOME DEFECTIVE F9 ACTIVATION 5 5.83e-01 0.142000 0.92900
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER 28 5.84e-01 -0.059800 0.92900
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 16 5.84e-01 0.079000 0.92900
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS 9 5.86e-01 -0.105000 0.92900
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE 17 5.86e-01 0.076400 0.92900
REACTOME SIGNALING BY WNT 318 5.87e-01 0.017700 0.92900
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING 9 5.87e-01 0.105000 0.92900
REACTOME SHC1 EVENTS IN EGFR SIGNALING 14 5.87e-01 -0.083900 0.92900
REACTOME MRNA CAPPING 28 5.87e-01 -0.059300 0.92900
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST 18 5.88e-01 0.073700 0.92900
REACTOME NETRIN 1 SIGNALING 49 5.88e-01 0.044700 0.92900
REACTOME AUTOPHAGY 144 5.89e-01 -0.026100 0.92900
REACTOME INWARDLY RECTIFYING K CHANNELS 35 5.92e-01 0.052400 0.93000
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS 38 5.92e-01 -0.050200 0.93000
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE 17 5.92e-01 -0.075000 0.93000
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION 27 5.94e-01 0.059300 0.93000
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15 8 5.94e-01 0.109000 0.93000
REACTOME FANCONI ANEMIA PATHWAY 35 5.95e-01 0.052000 0.93000
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES 39 5.96e-01 0.049100 0.93000
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO 10 5.96e-01 -0.096900 0.93000
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS 29 5.96e-01 -0.056800 0.93000
REACTOME RELAXIN RECEPTORS 8 5.97e-01 0.108000 0.93000
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION 19 5.98e-01 0.069900 0.93000
REACTOME ALK MUTANTS BIND TKIS 12 5.98e-01 0.088000 0.93000
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM 21 5.99e-01 0.066300 0.93000
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS 20 5.99e-01 -0.067900 0.93000
REACTOME TNF SIGNALING 54 5.99e-01 -0.041300 0.93000
REACTOME EFFECTS OF PIP2 HYDROLYSIS 26 6.00e-01 0.059400 0.93000
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2 12 6.00e-01 -0.087300 0.93000
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY 10 6.01e-01 -0.095500 0.93000
REACTOME CHYLOMICRON ASSEMBLY 10 6.01e-01 0.095400 0.93000
REACTOME PARACETAMOL ADME 26 6.01e-01 -0.059200 0.93000
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS 12 6.02e-01 0.086900 0.93000
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D 8 6.02e-01 0.106000 0.93000
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX 21 6.03e-01 -0.065600 0.93000
REACTOME RNA POLYMERASE I TRANSCRIPTION 102 6.04e-01 -0.029700 0.93000
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION 13 6.04e-01 0.083100 0.93000
REACTOME VOLTAGE GATED POTASSIUM CHANNELS 42 6.04e-01 -0.046200 0.93000
REACTOME SULFUR AMINO ACID METABOLISM 27 6.06e-01 0.057300 0.93200
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE 37 6.11e-01 -0.048400 0.93700
REACTOME ION CHANNEL TRANSPORT 172 6.11e-01 -0.022500 0.93700
REACTOME NEUROTRANSMITTER RELEASE CYCLE 48 6.11e-01 0.042400 0.93700
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS 19 6.12e-01 0.067300 0.93700
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY 41 6.13e-01 -0.045700 0.93700
REACTOME SIGNALING BY FLT3 FUSION PROTEINS 19 6.13e-01 -0.067000 0.93700
REACTOME METABOLISM OF FOLATE AND PTERINES 17 6.14e-01 -0.070700 0.93700
REACTOME CS DS DEGRADATION 12 6.14e-01 0.084000 0.93700
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA 9 6.15e-01 0.096900 0.93700
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS 16 6.16e-01 0.072500 0.93700
REACTOME RECEPTOR MEDIATED MITOPHAGY 10 6.16e-01 -0.091500 0.93700
REACTOME PI3K AKT ACTIVATION 9 6.16e-01 -0.096400 0.93700
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS 11 6.17e-01 0.087100 0.93700
REACTOME INTERFERON ALPHA BETA SIGNALING 70 6.18e-01 -0.034500 0.93700
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS 23 6.18e-01 0.060000 0.93700
REACTOME VASOPRESSIN LIKE RECEPTORS 5 6.19e-01 0.129000 0.93700
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 79 6.20e-01 0.032300 0.93800
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL 25 6.21e-01 0.057100 0.93900
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS 16 6.21e-01 -0.071300 0.93900
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS 14 6.24e-01 0.075800 0.94100
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS 5 6.24e-01 -0.126000 0.94100
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY 12 6.26e-01 0.081400 0.94100
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM 12 6.26e-01 0.081300 0.94100
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE 21 6.26e-01 -0.061400 0.94100
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION 10 6.28e-01 0.088500 0.94200
REACTOME L1CAM INTERACTIONS 112 6.28e-01 -0.026500 0.94200
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS 29 6.29e-01 -0.051800 0.94200
REACTOME DERMATAN SULFATE BIOSYNTHESIS 10 6.29e-01 0.088100 0.94200
REACTOME ION TRANSPORT BY P TYPE ATPASES 51 6.30e-01 -0.039000 0.94200
REACTOME TIGHT JUNCTION INTERACTIONS 29 6.31e-01 0.051500 0.94200
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK 47 6.31e-01 -0.040400 0.94200
REACTOME INSULIN PROCESSING 24 6.32e-01 -0.056500 0.94200
REACTOME NEUROTRANSMITTER CLEARANCE 9 6.32e-01 -0.092200 0.94200
REACTOME ERYTHROPOIETIN ACTIVATES STAT5 7 6.32e-01 0.104000 0.94200
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES 37 6.32e-01 0.045400 0.94200
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING 16 6.33e-01 -0.068900 0.94200
REACTOME RHO GTPASES ACTIVATE ROCKS 19 6.34e-01 -0.063100 0.94200
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS 83 6.35e-01 -0.030200 0.94200
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN 7 6.36e-01 0.103000 0.94300
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 255 6.39e-01 -0.017100 0.94300
REACTOME G2 M CHECKPOINTS 162 6.39e-01 0.021400 0.94300
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE 11 6.39e-01 -0.081700 0.94300
REACTOME RMTS METHYLATE HISTONE ARGININES 72 6.42e-01 0.031700 0.94300
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION 23 6.42e-01 0.056000 0.94300
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION 26 6.43e-01 -0.052500 0.94300
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING 6 6.44e-01 0.109000 0.94300
REACTOME MISMATCH REPAIR 15 6.44e-01 0.068900 0.94300
REACTOME PENTOSE PHOSPHATE PATHWAY 12 6.44e-01 -0.077000 0.94300
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION 98 6.45e-01 -0.027000 0.94300
REACTOME ACYL CHAIN REMODELLING OF PI 17 6.45e-01 0.064600 0.94300
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS 11 6.45e-01 0.080100 0.94300
REACTOME DRUG ADME 103 6.46e-01 -0.026200 0.94300
REACTOME CREB PHOSPHORYLATION 6 6.47e-01 -0.108000 0.94300
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING 24 6.48e-01 0.053900 0.94300
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE 22 6.48e-01 -0.056300 0.94300
REACTOME CHL1 INTERACTIONS 9 6.48e-01 -0.088000 0.94300
REACTOME MUCOPOLYSACCHARIDOSES 10 6.48e-01 -0.083400 0.94300
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE 7 6.48e-01 -0.099600 0.94300
REACTOME UB SPECIFIC PROCESSING PROTEASES 187 6.50e-01 0.019300 0.94300
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL 24 6.51e-01 -0.053400 0.94300
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA 17 6.51e-01 0.063500 0.94300
REACTOME MYOCLONIC EPILEPSY OF LAFORA 9 6.51e-01 0.087100 0.94300
REACTOME GLYCOSAMINOGLYCAN METABOLISM 118 6.51e-01 -0.024100 0.94300
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 11 6.52e-01 0.078600 0.94300
REACTOME SYNTHESIS OF PG 8 6.52e-01 0.092100 0.94300
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB 10 6.52e-01 0.082400 0.94300
REACTOME DEGRADATION OF DVL 56 6.53e-01 0.034700 0.94300
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI 5 6.53e-01 0.116000 0.94300
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES 8 6.54e-01 -0.091400 0.94300
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION 5 6.54e-01 0.116000 0.94300
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS 6 6.54e-01 0.106000 0.94300
REACTOME BASE EXCISION REPAIR 87 6.57e-01 -0.027600 0.94400
REACTOME DISSOLUTION OF FIBRIN CLOT 13 6.58e-01 0.070900 0.94400
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS 170 6.59e-01 0.019600 0.94400
REACTOME PROTEIN UBIQUITINATION 76 6.59e-01 0.029300 0.94400
REACTOME MET RECEPTOR ACTIVATION 6 6.59e-01 0.104000 0.94400
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS 16 6.59e-01 -0.063600 0.94400
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION 19 6.60e-01 0.058200 0.94400
REACTOME RHOC GTPASE CYCLE 71 6.60e-01 0.030200 0.94400
REACTOME MICRORNA MIRNA BIOGENESIS 25 6.61e-01 0.050700 0.94400
REACTOME SULFIDE OXIDATION TO SULFATE 6 6.61e-01 0.103000 0.94400
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT 23 6.61e-01 -0.052800 0.94400
REACTOME EPHB MEDIATED FORWARD SIGNALING 41 6.61e-01 0.039500 0.94400
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS 8 6.64e-01 -0.088700 0.94500
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME 11 6.64e-01 0.075600 0.94500
REACTOME KEAP1 NFE2L2 PATHWAY 104 6.64e-01 0.024600 0.94500
REACTOME SPHINGOLIPID METABOLISM 84 6.65e-01 0.027400 0.94500
REACTOME HCMV LATE EVENTS 110 6.66e-01 -0.023800 0.94500
REACTOME UBIQUINOL BIOSYNTHESIS 8 6.67e-01 -0.087800 0.94500
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION 5 6.67e-01 -0.111000 0.94500
REACTOME COPII MEDIATED VESICLE TRANSPORT 66 6.69e-01 -0.030500 0.94500
REACTOME SYNTHESIS OF PI 5 6.69e-01 0.110000 0.94500
REACTOME SIGNALING BY ERBB2 IN CANCER 26 6.70e-01 0.048300 0.94500
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS 16 6.71e-01 0.061400 0.94500
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS 7 6.71e-01 -0.092800 0.94500
REACTOME MET RECEPTOR RECYCLING 10 6.71e-01 0.077500 0.94500
REACTOME SIGNALING BY LRP5 MUTANTS 6 6.71e-01 0.100000 0.94500
REACTOME INTRA GOLGI TRAFFIC 43 6.73e-01 0.037200 0.94500
REACTOME INSULIN RECEPTOR RECYCLING 29 6.73e-01 0.045300 0.94500
REACTOME CELL CYCLE 666 6.73e-01 -0.009570 0.94500
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR 21 6.74e-01 0.053100 0.94500
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING 46 6.74e-01 0.035800 0.94500
REACTOME ANTIMICROBIAL PEPTIDES 76 6.75e-01 -0.027800 0.94500
REACTOME PINK1 PRKN MEDIATED MITOPHAGY 22 6.75e-01 0.051600 0.94500
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING 17 6.75e-01 -0.058600 0.94500
REACTOME FCERI MEDIATED MAPK ACTIVATION 32 6.76e-01 0.042700 0.94500
REACTOME PROLONGED ERK ACTIVATION EVENTS 14 6.76e-01 -0.064500 0.94500
REACTOME SIGNALING BY FGFR IN DISEASE 62 6.77e-01 0.030500 0.94600
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS 33 6.80e-01 0.041500 0.94600
REACTOME CREATINE METABOLISM 9 6.80e-01 0.079400 0.94600
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY 33 6.80e-01 0.041500 0.94600
REACTOME EXTENSION OF TELOMERES 49 6.80e-01 0.034000 0.94600
REACTOME FASL CD95L SIGNALING 5 6.81e-01 -0.106000 0.94600
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA 5 6.82e-01 0.106000 0.94600
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION 24 6.83e-01 0.048200 0.94600
REACTOME DEADENYLATION DEPENDENT MRNA DECAY 56 6.83e-01 -0.031600 0.94600
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL 13 6.83e-01 0.065400 0.94600
REACTOME RHOH GTPASE CYCLE 37 6.84e-01 -0.038700 0.94700
REACTOME PHOSPHORYLATION OF EMI1 6 6.85e-01 0.095500 0.94800
REACTOME METABOLISM OF PORPHYRINS 26 6.87e-01 0.045600 0.95000
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS 12 6.88e-01 -0.067000 0.95000
REACTOME FRUCTOSE METABOLISM 7 6.88e-01 0.087600 0.95000
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE 9 6.90e-01 -0.076900 0.95000
REACTOME CHOLINE CATABOLISM 6 6.90e-01 0.094100 0.95000
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 22 6.90e-01 0.049100 0.95000
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES 34 6.91e-01 0.039400 0.95000
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE 52 6.92e-01 -0.031800 0.95000
REACTOME METHIONINE SALVAGE PATHWAY 6 6.93e-01 -0.093200 0.95000
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER 25 6.93e-01 0.045600 0.95000
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE 277 6.94e-01 -0.013700 0.95000
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS 41 6.94e-01 -0.035500 0.95000
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY 10 6.94e-01 0.071800 0.95000
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE 11 6.95e-01 0.068200 0.95000
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER 25 6.96e-01 -0.045200 0.95000
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT 5 6.96e-01 0.101000 0.95000
REACTOME ANDROGEN BIOSYNTHESIS 11 6.97e-01 -0.067900 0.95000
REACTOME APOPTOTIC EXECUTION PHASE 49 6.97e-01 0.032200 0.95000
REACTOME SIGNALING BY FGFR2 IIIA TM 19 6.98e-01 -0.051400 0.95000
REACTOME METABOLISM OF NUCLEOTIDES 94 6.99e-01 0.023100 0.95000
REACTOME RAS PROCESSING 22 6.99e-01 0.047600 0.95000
REACTOME HIV TRANSCRIPTION INITIATION 43 6.99e-01 0.034000 0.95000
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN 21 7.01e-01 0.048400 0.95100
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE 81 7.01e-01 0.024700 0.95100
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS 19 7.02e-01 0.050700 0.95100
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS 63 7.05e-01 -0.027600 0.95300
REACTOME SHC MEDIATED CASCADE FGFR4 19 7.06e-01 0.050000 0.95300
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS 28 7.06e-01 0.041200 0.95300
REACTOME NGF INDEPENDANT TRKA ACTIVATION 5 7.06e-01 -0.097300 0.95300
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM 50 7.06e-01 -0.030800 0.95300
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 236 7.09e-01 -0.014100 0.95600
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS 9 7.12e-01 0.071000 0.96000
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP 12 7.13e-01 0.061300 0.96000
REACTOME SIGNAL TRANSDUCTION BY L1 20 7.14e-01 -0.047400 0.96000
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION 1356 7.15e-01 -0.005910 0.96000
REACTOME INTERLEUKIN 36 PATHWAY 7 7.15e-01 0.079700 0.96000
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION 10 7.15e-01 0.066600 0.96000
REACTOME STRIATED MUSCLE CONTRACTION 35 7.16e-01 -0.035500 0.96000
REACTOME COMPLEX I BIOGENESIS 49 7.18e-01 0.029800 0.96200
REACTOME SYNTHESIS OF PA 38 7.19e-01 0.033700 0.96200
REACTOME CELLULAR RESPONSE TO HEAT STRESS 99 7.20e-01 0.020800 0.96300
REACTOME MISCELLANEOUS SUBSTRATES 12 7.21e-01 0.059600 0.96300
REACTOME CRMPS IN SEMA3A SIGNALING 15 7.23e-01 -0.052800 0.96300
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS 5 7.24e-01 -0.091300 0.96300
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION 19 7.24e-01 -0.046800 0.96300
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS 25 7.25e-01 0.040700 0.96300
REACTOME CYTOPROTECTION BY HMOX1 59 7.25e-01 0.026500 0.96300
REACTOME NEUREXINS AND NEUROLIGINS 51 7.25e-01 0.028500 0.96300
REACTOME RESOLUTION OF D LOOP STRUCTURES 33 7.25e-01 0.035400 0.96300
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES 22 7.26e-01 0.043200 0.96300
REACTOME O LINKED GLYCOSYLATION OF MUCINS 61 7.27e-01 -0.025800 0.96300
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS 39 7.27e-01 0.032300 0.96300
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE 5 7.28e-01 0.089700 0.96300
REACTOME GABA RECEPTOR ACTIVATION 57 7.29e-01 0.026600 0.96300
REACTOME SIGNALING BY NUCLEAR RECEPTORS 283 7.29e-01 -0.012000 0.96300
REACTOME PRE NOTCH PROCESSING IN GOLGI 18 7.29e-01 0.047100 0.96300
REACTOME OAS ANTIVIRAL RESPONSE 8 7.29e-01 0.070600 0.96300
REACTOME CIPROFLOXACIN ADME 5 7.31e-01 -0.088900 0.96400
REACTOME INDUCTION OF CELL CELL FUSION 12 7.31e-01 -0.057300 0.96400
REACTOME RHOBTB GTPASE CYCLE 34 7.33e-01 0.033800 0.96500
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION 9 7.33e-01 0.065600 0.96500
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS 12 7.35e-01 -0.056300 0.96600
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS 20 7.36e-01 0.043600 0.96600
REACTOME MITOTIC SPINDLE CHECKPOINT 109 7.37e-01 -0.018600 0.96700
REACTOME ACYL CHAIN REMODELLING OF PG 18 7.38e-01 0.045600 0.96700
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING 34 7.38e-01 -0.033200 0.96700
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM 7 7.38e-01 -0.073000 0.96700
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS 9 7.39e-01 -0.064000 0.96800
REACTOME LAGGING STRAND SYNTHESIS 19 7.41e-01 0.043800 0.96800
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS 9 7.41e-01 -0.063700 0.96800
REACTOME DEFENSINS 33 7.44e-01 -0.032800 0.97100
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION 8 7.45e-01 -0.066500 0.97100
REACTOME THYROXINE BIOSYNTHESIS 10 7.45e-01 0.059400 0.97100
REACTOME RIPK1 MEDIATED REGULATED NECROSIS 30 7.46e-01 0.034100 0.97100
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS 8 7.46e-01 -0.066000 0.97100
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE 71 7.47e-01 -0.022200 0.97100
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING 22 7.48e-01 0.039600 0.97100
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION 8 7.49e-01 -0.065400 0.97100
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER 49 7.49e-01 0.026400 0.97100
REACTOME KERATAN SULFATE BIOSYNTHESIS 28 7.50e-01 -0.034800 0.97200
REACTOME RHOV GTPASE CYCLE 36 7.52e-01 -0.030500 0.97200
REACTOME DNA REPLICATION PRE INITIATION 150 7.52e-01 0.015000 0.97200
REACTOME INTERLEUKIN 1 PROCESSING 9 7.52e-01 0.060800 0.97200
REACTOME RHOG GTPASE CYCLE 71 7.53e-01 0.021600 0.97200
REACTOME DEUBIQUITINATION 260 7.53e-01 0.011300 0.97200
REACTOME EGFR DOWNREGULATION 30 7.54e-01 0.033100 0.97200
REACTOME DISINHIBITION OF SNARE FORMATION 5 7.56e-01 0.080300 0.97400
REACTOME POTENTIAL THERAPEUTICS FOR SARS 92 7.57e-01 -0.018700 0.97400
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R 9 7.58e-01 -0.059400 0.97400
REACTOME G2 M DNA REPLICATION CHECKPOINT 5 7.58e-01 0.079600 0.97400
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS 10 7.58e-01 -0.056300 0.97400
REACTOME METABOLISM OF AMINE DERIVED HORMONES 17 7.59e-01 0.043000 0.97400
REACTOME POLYMERASE SWITCHING 13 7.59e-01 -0.049000 0.97400
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS 10 7.61e-01 0.055600 0.97400
REACTOME RUNX2 REGULATES BONE DEVELOPMENT 29 7.63e-01 0.032400 0.97400
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 25 7.64e-01 0.034800 0.97400
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE 69 7.65e-01 0.020800 0.97400
REACTOME PHENYLALANINE METABOLISM 6 7.65e-01 -0.070500 0.97400
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY 30 7.65e-01 -0.031500 0.97400
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA 77 7.65e-01 0.019700 0.97400
REACTOME ACTIVATION OF SMO 18 7.67e-01 0.040300 0.97400
REACTOME HDR THROUGH MMEJ ALT NHEJ 12 7.68e-01 0.049300 0.97400
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY 5 7.68e-01 -0.076200 0.97400
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE 19 7.69e-01 0.039000 0.97400
REACTOME EARLY SARS COV 2 INFECTION EVENTS 34 7.69e-01 -0.029100 0.97400
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION 7 7.70e-01 -0.063800 0.97400
REACTOME ANCHORING FIBRIL FORMATION 13 7.71e-01 0.046600 0.97400
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN 15 7.71e-01 0.043300 0.97400
REACTOME DIGESTION OF DIETARY LIPID 7 7.73e-01 -0.062900 0.97400
REACTOME DNA DOUBLE STRAND BREAK REPAIR 162 7.73e-01 -0.013100 0.97400
REACTOME HOMOLOGY DIRECTED REPAIR 132 7.74e-01 -0.014500 0.97400
REACTOME SIGNALLING TO P38 VIA RIT AND RIN 5 7.75e-01 0.074000 0.97400
REACTOME GDP FUCOSE BIOSYNTHESIS 6 7.75e-01 -0.067500 0.97400
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS 50 7.76e-01 0.023300 0.97400
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS 36 7.76e-01 0.027400 0.97400
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER 76 7.76e-01 -0.018800 0.97400
REACTOME RESPONSE TO METAL IONS 14 7.77e-01 0.043800 0.97400
REACTOME P38MAPK EVENTS 13 7.77e-01 -0.045400 0.97400
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS 13 7.77e-01 -0.045400 0.97400
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE 17 7.77e-01 -0.039600 0.97400
REACTOME MUSCLE CONTRACTION 197 7.77e-01 -0.011700 0.97400
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1 229 7.78e-01 0.010800 0.97400
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS 10 7.78e-01 -0.051400 0.97400
REACTOME SIGNALING BY RETINOIC ACID 41 7.79e-01 0.025300 0.97400
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS 6 7.81e-01 -0.065600 0.97400
REACTOME DSCAM INTERACTIONS 11 7.81e-01 0.048400 0.97400
REACTOME FERTILIZATION 26 7.81e-01 -0.031500 0.97400
REACTOME PHYSIOLOGICAL FACTORS 14 7.81e-01 0.042800 0.97400
REACTOME ACTIVATION OF RAC1 12 7.82e-01 -0.046200 0.97400
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS 17 7.82e-01 0.038800 0.97400
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES 16 7.82e-01 -0.040000 0.97400
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2 11 7.83e-01 -0.048000 0.97400
REACTOME ROBO RECEPTORS BIND AKAP5 9 7.84e-01 0.052600 0.97500
REACTOME INTERLEUKIN 35 SIGNALLING 12 7.85e-01 0.045500 0.97500
REACTOME ACYL CHAIN REMODELING OF CL 5 7.86e-01 0.070100 0.97500
REACTOME EICOSANOIDS 12 7.86e-01 -0.045200 0.97500
REACTOME REGULATION OF IFNG SIGNALING 14 7.86e-01 0.041800 0.97500
REACTOME SERINE BIOSYNTHESIS 9 7.87e-01 0.052000 0.97500
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN 13 7.88e-01 0.043100 0.97600
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA 5 7.90e-01 0.068900 0.97600
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION 34 7.90e-01 -0.026400 0.97600
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA 5 7.91e-01 0.068400 0.97600
REACTOME PHASE 3 RAPID REPOLARISATION 8 7.92e-01 0.053700 0.97600
REACTOME SENSORY PERCEPTION OF TASTE 47 7.93e-01 0.022100 0.97600
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION 7 7.95e-01 -0.056800 0.97600
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS 25 7.95e-01 0.030100 0.97600
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS 7 7.95e-01 -0.056700 0.97600
REACTOME FORMATION OF PARAXIAL MESODERM 22 7.96e-01 -0.031900 0.97600
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS 14 7.96e-01 -0.040000 0.97600
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING 14 7.96e-01 -0.039800 0.97600
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE 5 7.97e-01 0.066500 0.97600
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION 23 7.97e-01 0.031000 0.97600
REACTOME ARACHIDONATE PRODUCTION FROM DAG 5 7.97e-01 0.066400 0.97600
REACTOME CELL CYCLE CHECKPOINTS 284 7.97e-01 0.008850 0.97600
REACTOME REGULATION OF PTEN MRNA TRANSLATION 9 7.98e-01 0.049300 0.97600
REACTOME MASTL FACILITATES MITOTIC PROGRESSION 10 7.99e-01 0.046500 0.97700
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION 9 8.01e-01 0.048600 0.97700
REACTOME RA BIOSYNTHESIS PATHWAY 22 8.01e-01 -0.031000 0.97700
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS 22 8.03e-01 0.030800 0.97700
REACTOME SIGNALLING TO ERKS 34 8.04e-01 -0.024600 0.97700
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA 7 8.04e-01 -0.054200 0.97700
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS 35 8.05e-01 0.024200 0.97700
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION 5 8.05e-01 -0.063900 0.97700
REACTOME DISEASES OF MISMATCH REPAIR MMR 5 8.05e-01 0.063800 0.97700
REACTOME LIPOPHAGY 9 8.06e-01 0.047300 0.97700
REACTOME HSF1 ACTIVATION 29 8.06e-01 -0.026400 0.97700
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE 29 8.07e-01 0.026200 0.97700
REACTOME CARDIAC CONDUCTION 125 8.07e-01 -0.012600 0.97700
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 101 8.08e-01 -0.014000 0.97700
REACTOME HEME SIGNALING 47 8.08e-01 0.020500 0.97700
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE 11 8.08e-01 0.042200 0.97700
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY 74 8.10e-01 0.016100 0.97800
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX 51 8.11e-01 -0.019400 0.97800
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS 8 8.11e-01 0.048700 0.97800
REACTOME SIGNALING BY FGFR4 IN DISEASE 11 8.11e-01 -0.041500 0.97800
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES 9 8.12e-01 0.045800 0.97800
REACTOME CGMP EFFECTS 16 8.13e-01 -0.034100 0.97800
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS 9 8.13e-01 0.045400 0.97800
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER 18 8.14e-01 -0.032000 0.97800
REACTOME INTEGRATION OF PROVIRUS 9 8.15e-01 0.045100 0.97800
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE 20 8.16e-01 0.030000 0.97800
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS 39 8.17e-01 -0.021400 0.97800
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS 121 8.17e-01 -0.012200 0.97800
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR 19 8.19e-01 -0.030300 0.97800
REACTOME PHENYLALANINE AND TYROSINE METABOLISM 11 8.20e-01 -0.039600 0.97800
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA 263 8.21e-01 0.008110 0.97800
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE 10 8.21e-01 0.041200 0.97800
REACTOME GLUTATHIONE CONJUGATION 33 8.22e-01 0.022700 0.97800
REACTOME NETRIN MEDIATED REPULSION SIGNALS 8 8.22e-01 0.046000 0.97800
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS 6 8.23e-01 -0.052800 0.97800
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION 6 8.24e-01 -0.052600 0.97800
REACTOME NRCAM INTERACTIONS 6 8.24e-01 0.052400 0.97800
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION 5 8.24e-01 0.057300 0.97800
REACTOME METABOLISM OF VITAMINS AND COFACTORS 185 8.25e-01 -0.009430 0.97800
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING 14 8.25e-01 0.034000 0.97800
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE 17 8.27e-01 -0.030700 0.97800
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS 11 8.27e-01 0.038000 0.97800
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION 27 8.27e-01 0.024200 0.97800
REACTOME HYALURONAN UPTAKE AND DEGRADATION 12 8.29e-01 -0.036100 0.97800
REACTOME ION HOMEOSTASIS 52 8.29e-01 0.017300 0.97800
REACTOME METABOLISM OF COFACTORS 19 8.29e-01 0.028600 0.97800
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA 6 8.30e-01 0.050800 0.97800
REACTOME SEPARATION OF SISTER CHROMATIDS 184 8.30e-01 -0.009180 0.97800
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER 28 8.31e-01 0.023300 0.97800
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA 17 8.31e-01 0.029900 0.97800
REACTOME CELL CELL COMMUNICATION 126 8.32e-01 0.010900 0.97800
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES 6 8.33e-01 0.049800 0.97800
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1 16 8.33e-01 0.030400 0.97800
REACTOME RNA POLYMERASE III CHAIN ELONGATION 18 8.33e-01 -0.028700 0.97800
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS 10 8.33e-01 -0.038400 0.97800
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS 81 8.35e-01 -0.013400 0.97800
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX 41 8.35e-01 0.018800 0.97800
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE 16 8.35e-01 0.030100 0.97800
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX 5 8.35e-01 0.053800 0.97800
REACTOME VESICLE MEDIATED TRANSPORT 642 8.36e-01 -0.004800 0.97800
REACTOME THE NLRP3 INFLAMMASOME 16 8.36e-01 0.030000 0.97800
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL 58 8.36e-01 0.015700 0.97800
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY 5 8.36e-01 0.053300 0.97800
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES 28 8.39e-01 0.022200 0.97800
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES 18 8.40e-01 -0.027500 0.97800
REACTOME INTEGRATION OF ENERGY METABOLISM 105 8.40e-01 0.011400 0.97800
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED 6 8.41e-01 0.047300 0.97800
REACTOME CALCINEURIN ACTIVATES NFAT 9 8.41e-01 -0.038500 0.97800
REACTOME AZATHIOPRINE ADME 22 8.41e-01 -0.024600 0.97800
REACTOME HS GAG DEGRADATION 19 8.42e-01 -0.026500 0.97800
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS 18 8.42e-01 0.027200 0.97800
REACTOME MITOCHONDRIAL TRANSLATION 93 8.42e-01 0.011900 0.97800
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS 23 8.42e-01 0.024000 0.97800
REACTOME RHO GTPASES ACTIVATE CIT 19 8.45e-01 0.026000 0.97800
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII 15 8.45e-01 -0.029100 0.97800
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT 18 8.46e-01 -0.026400 0.97800
REACTOME MET PROMOTES CELL MOTILITY 41 8.47e-01 -0.017400 0.97800
REACTOME DEADENYLATION OF MRNA 25 8.47e-01 -0.022200 0.97800
REACTOME MITOPHAGY 28 8.48e-01 0.021000 0.97800
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY 67 8.49e-01 0.013500 0.97800
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS 7 8.49e-01 -0.041700 0.97800
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA 14 8.49e-01 0.029400 0.97800
REACTOME SIGNALING BY HEDGEHOG 148 8.49e-01 0.009080 0.97800
REACTOME DNA REPLICATION 178 8.49e-01 0.008260 0.97800
REACTOME SIALIC ACID METABOLISM 33 8.50e-01 -0.019000 0.97800
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA 27 8.50e-01 0.021000 0.97800
REACTOME MYOGENESIS 29 8.52e-01 0.020100 0.97900
REACTOME KILLING MECHANISMS 11 8.53e-01 0.032300 0.97900
REACTOME DEFECTIVE CHST6 CAUSES MCDC1 8 8.55e-01 0.037200 0.98000
REACTOME NEUROFASCIN INTERACTIONS 6 8.56e-01 0.042900 0.98000
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS 7 8.57e-01 0.039400 0.98000
REACTOME ATTENUATION PHASE 27 8.57e-01 -0.020000 0.98000
REACTOME IRON UPTAKE AND TRANSPORT 56 8.58e-01 0.013800 0.98000
REACTOME PROTEIN FOLDING 96 8.59e-01 0.010500 0.98000
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING 30 8.59e-01 0.018700 0.98000
REACTOME MRNA SPLICING 197 8.60e-01 -0.007290 0.98000
REACTOME PREGNENOLONE BIOSYNTHESIS 12 8.61e-01 0.029200 0.98000
REACTOME PYRIMIDINE CATABOLISM 12 8.61e-01 -0.029100 0.98000
REACTOME PLATELET CALCIUM HOMEOSTASIS 27 8.61e-01 -0.019400 0.98000
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 122 8.62e-01 -0.009100 0.98000
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1 20 8.62e-01 0.022400 0.98000
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION 14 8.63e-01 0.026700 0.98000
REACTOME BIOLOGICAL OXIDATIONS 210 8.63e-01 0.006920 0.98000
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION 26 8.65e-01 -0.019200 0.98200
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES 34 8.66e-01 -0.016700 0.98200
REACTOME HISTIDINE CATABOLISM 8 8.66e-01 -0.034400 0.98200
REACTOME VITAMIN B1 THIAMIN METABOLISM 5 8.67e-01 -0.043300 0.98200
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING 8 8.67e-01 -0.034200 0.98200
REACTOME RHOU GTPASE CYCLE 37 8.71e-01 0.015400 0.98600
REACTOME MEMBRANE TRAFFICKING 603 8.73e-01 -0.003810 0.98600
REACTOME CLEC7A INFLAMMASOME PATHWAY 6 8.73e-01 0.037600 0.98600
REACTOME RRNA PROCESSING IN THE MITOCHONDRION 9 8.73e-01 -0.030700 0.98600
REACTOME SYNTHESIS OF PE 13 8.74e-01 -0.025400 0.98600
REACTOME HSF1 DEPENDENT TRANSACTIVATION 37 8.75e-01 -0.015000 0.98600
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION 30 8.77e-01 0.016300 0.98800
REACTOME SIGNALING BY BMP 27 8.79e-01 -0.017000 0.98800
REACTOME NUCLEOTIDE EXCISION REPAIR 107 8.79e-01 -0.008500 0.98800
REACTOME INOSITOL PHOSPHATE METABOLISM 45 8.79e-01 -0.013100 0.98800
REACTOME RHOQ GTPASE CYCLE 57 8.79e-01 -0.011600 0.98800
REACTOME INTERFERON SIGNALING 193 8.79e-01 -0.006340 0.98800
REACTOME SIGNALING BY MET 78 8.81e-01 -0.009820 0.98900
REACTOME SYNDECAN INTERACTIONS 26 8.82e-01 -0.016800 0.98900
REACTOME NEDDYLATION 235 8.83e-01 0.005570 0.99000
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES 6 8.84e-01 0.034500 0.99000
REACTOME METHYLATION 14 8.85e-01 0.022400 0.99000
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS 23 8.85e-01 -0.017400 0.99000
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM 45 8.86e-01 0.012400 0.99000
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING 32 8.86e-01 0.014700 0.99000
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS 58 8.88e-01 0.010600 0.99200
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM 16 8.91e-01 0.019800 0.99200
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS 20 8.92e-01 -0.017600 0.99200
REACTOME RHOJ GTPASE CYCLE 51 8.92e-01 -0.011000 0.99200
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS 20 8.92e-01 -0.017500 0.99200
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY 17 8.92e-01 0.019000 0.99200
REACTOME TRANSCRIPTION OF THE HIV GENOME 66 8.93e-01 -0.009580 0.99200
REACTOME MAPK1 ERK2 ACTIVATION 9 8.93e-01 -0.025800 0.99200
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS 9 8.94e-01 -0.025700 0.99200
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS 27 8.95e-01 0.014600 0.99300
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS 7 8.97e-01 0.028300 0.99300
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS 14 8.98e-01 0.019800 0.99300
REACTOME THE ACTIVATION OF ARYLSULFATASES 8 8.99e-01 0.025900 0.99300
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION 9 8.99e-01 -0.024300 0.99300
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS 11 9.00e-01 0.021900 0.99300
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS 19 9.00e-01 0.016600 0.99300
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL 14 9.00e-01 0.019300 0.99300
REACTOME TRANSPORT OF SMALL MOLECULES 697 9.01e-01 0.002780 0.99300
REACTOME MITOTIC G2 G2 M PHASES 194 9.01e-01 -0.005180 0.99300
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS 54 9.01e-01 0.009750 0.99300
REACTOME SIGNALING BY MST1 5 9.02e-01 -0.031900 0.99300
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX 14 9.04e-01 -0.018700 0.99400
REACTOME METABOLISM OF STEROIDS 150 9.06e-01 -0.005610 0.99400
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION 6 9.07e-01 0.027700 0.99400
REACTOME TRANSPORT OF RCBL WITHIN THE BODY 8 9.07e-01 -0.023900 0.99400
REACTOME LATE SARS COV 2 INFECTION EVENTS 67 9.07e-01 -0.008230 0.99400
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS 42 9.08e-01 -0.010400 0.99400
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE 30 9.08e-01 0.012200 0.99400
REACTOME MAPK3 ERK1 ACTIVATION 10 9.08e-01 0.021100 0.99400
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS 41 9.08e-01 0.010400 0.99400
REACTOME SYNAPTIC ADHESION LIKE MOLECULES 19 9.11e-01 0.014900 0.99400
REACTOME RETINOID CYCLE DISEASE EVENTS 11 9.12e-01 -0.019300 0.99400
REACTOME SMOOTH MUSCLE CONTRACTION 43 9.12e-01 -0.009750 0.99400
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS 5 9.12e-01 -0.028500 0.99400
REACTOME LGI ADAM INTERACTIONS 14 9.13e-01 0.016900 0.99400
REACTOME RUNX3 REGULATES P14 ARF 10 9.13e-01 -0.019900 0.99400
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT 19 9.13e-01 0.014400 0.99400
REACTOME CARGO CONCENTRATION IN THE ER 32 9.14e-01 0.011100 0.99400
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES 77 9.14e-01 0.007100 0.99400
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS 5 9.15e-01 -0.027600 0.99400
REACTOME FORMATION OF LATERAL PLATE MESODERM 5 9.15e-01 0.027600 0.99400
REACTOME SIGNALING BY MAPK MUTANTS 6 9.15e-01 0.025200 0.99400
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7 12 9.17e-01 0.017500 0.99400
REACTOME ETHANOL OXIDATION 12 9.18e-01 -0.017200 0.99400
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION 19 9.19e-01 0.013500 0.99400
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS 29 9.19e-01 0.010900 0.99400
REACTOME ACYL CHAIN REMODELLING OF PE 29 9.20e-01 0.010800 0.99400
REACTOME INTERLEUKIN 27 SIGNALING 11 9.21e-01 0.017300 0.99400
REACTOME HEDGEHOG OFF STATE 111 9.22e-01 -0.005410 0.99400
REACTOME SIGNALING BY KIT IN DISEASE 20 9.22e-01 -0.012600 0.99400
REACTOME SARS COV 2 MODULATES AUTOPHAGY 11 9.23e-01 -0.016900 0.99400
REACTOME RHO GTPASES ACTIVATE KTN1 11 9.23e-01 0.016800 0.99400
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE 25 9.23e-01 -0.011100 0.99400
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE 16 9.24e-01 0.013800 0.99400
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 19 9.24e-01 -0.012600 0.99400
REACTOME SIGNALING BY PDGFR IN DISEASE 20 9.24e-01 0.012300 0.99400
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES 61 9.25e-01 0.007000 0.99400
REACTOME INTERLEUKIN 7 SIGNALING 31 9.28e-01 0.009400 0.99400
REACTOME TELOMERE EXTENSION BY TELOMERASE 22 9.29e-01 0.011100 0.99400
REACTOME EPH EPHRIN SIGNALING 90 9.30e-01 0.005350 0.99400
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY 14 9.30e-01 0.013500 0.99400
REACTOME CITRIC ACID CYCLE TCA CYCLE 21 9.30e-01 -0.011000 0.99400
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING 12 9.31e-01 -0.014500 0.99400
REACTOME GLYCOGEN SYNTHESIS 13 9.32e-01 0.013700 0.99400
REACTOME PROTEIN REPAIR 6 9.33e-01 0.019800 0.99400
REACTOME MET INTERACTS WITH TNS PROTEINS 5 9.34e-01 0.021500 0.99400
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS 10 9.34e-01 0.015100 0.99400
REACTOME DEFECTIVE LFNG CAUSES SCDO3 5 9.35e-01 0.021200 0.99400
REACTOME TP53 REGULATES METABOLIC GENES 81 9.36e-01 -0.005190 0.99400
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER 5 9.36e-01 0.020800 0.99400
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS 14 9.36e-01 -0.012400 0.99400
REACTOME LYSOSOME VESICLE BIOGENESIS 33 9.36e-01 0.008050 0.99400
REACTOME GLYCOSPHINGOLIPID METABOLISM 39 9.37e-01 -0.007340 0.99400
REACTOME SCAVENGING BY CLASS A RECEPTORS 19 9.38e-01 0.010400 0.99400
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS 7 9.38e-01 0.017000 0.99400
REACTOME GLYCOGEN METABOLISM 22 9.39e-01 0.009370 0.99400
REACTOME POTASSIUM CHANNELS 102 9.40e-01 -0.004350 0.99400
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS 19 9.40e-01 -0.010000 0.99400
REACTOME MET ACTIVATES RAS SIGNALING 11 9.40e-01 0.013100 0.99400
REACTOME MITOTIC METAPHASE AND ANAPHASE 228 9.40e-01 -0.002890 0.99400
REACTOME GLYCOGEN STORAGE DISEASES 15 9.41e-01 0.011100 0.99400
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB 19 9.42e-01 -0.009720 0.99400
REACTOME DEATH RECEPTOR SIGNALING 143 9.42e-01 -0.003530 0.99400
REACTOME 2 LTR CIRCLE FORMATION 7 9.42e-01 0.015900 0.99400
REACTOME BICARBONATE TRANSPORTERS 10 9.42e-01 0.013200 0.99400
REACTOME PURINE CATABOLISM 17 9.43e-01 0.010000 0.99400
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION 10 9.44e-01 0.012800 0.99400
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS 10 9.45e-01 -0.012600 0.99400
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS 93 9.46e-01 -0.004040 0.99400
REACTOME G2 M DNA DAMAGE CHECKPOINT 90 9.46e-01 0.004110 0.99400
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS 38 9.47e-01 0.006280 0.99400
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS 9 9.47e-01 -0.012700 0.99400
REACTOME ADRENOCEPTORS 9 9.48e-01 -0.012700 0.99400
REACTOME EPHRIN SIGNALING 17 9.49e-01 -0.009020 0.99400
REACTOME KERATAN SULFATE KERATIN METABOLISM 34 9.49e-01 -0.006370 0.99400
REACTOME PLASMA LIPOPROTEIN REMODELING 33 9.49e-01 -0.006400 0.99400
REACTOME VLDL ASSEMBLY 5 9.49e-01 0.016400 0.99400
REACTOME SIGNALING BY VEGF 102 9.49e-01 -0.003640 0.99400
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES 33 9.51e-01 -0.006210 0.99400
REACTOME SIGNALING BY ACTIVIN 15 9.52e-01 -0.009010 0.99400
REACTOME PLATELET HOMEOSTASIS 85 9.53e-01 -0.003720 0.99400
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE 8 9.55e-01 0.011600 0.99400
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS 14 9.55e-01 -0.008690 0.99400
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION 27 9.55e-01 -0.006240 0.99400
REACTOME CA DEPENDENT EVENTS 36 9.56e-01 0.005340 0.99400
REACTOME VLDLR INTERNALISATION AND DEGRADATION 16 9.56e-01 0.007990 0.99400
REACTOME IRE1ALPHA ACTIVATES CHAPERONES 48 9.58e-01 0.004370 0.99400
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS 8 9.58e-01 0.010700 0.99400
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION 6 9.58e-01 -0.012300 0.99400
REACTOME N GLYCAN ANTENNAE ELONGATION 15 9.58e-01 -0.007770 0.99400
REACTOME OVARIAN TUMOR DOMAIN PROTEASES 36 9.59e-01 -0.004980 0.99400
REACTOME TRNA AMINOACYLATION 40 9.60e-01 -0.004580 0.99400
REACTOME INFLAMMASOMES 21 9.61e-01 -0.006200 0.99400
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS 15 9.61e-01 0.007260 0.99400
REACTOME DECTIN 2 FAMILY 26 9.65e-01 -0.004940 0.99400
REACTOME PYRUVATE METABOLISM 29 9.67e-01 0.004390 0.99400
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING 13 9.67e-01 -0.006540 0.99400
REACTOME SIGNALING BY ERBB2 ECD MUTANTS 16 9.68e-01 -0.005880 0.99400
REACTOME RNA POLYMERASE III TRANSCRIPTION 41 9.68e-01 -0.003660 0.99400
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS 11 9.68e-01 0.007030 0.99400
REACTOME CROSSLINKING OF COLLAGEN FIBRILS 16 9.68e-01 -0.005760 0.99400
REACTOME SYNTHESIS OF PC 27 9.69e-01 0.004390 0.99400
REACTOME DUAL INCISION IN GG NER 39 9.69e-01 -0.003600 0.99400
REACTOME INTERLEUKIN 6 SIGNALING 11 9.70e-01 0.006460 0.99400
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 11 9.71e-01 0.006380 0.99400
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS 6 9.72e-01 -0.008300 0.99400
REACTOME NUCLEOTIDE SALVAGE 21 9.73e-01 -0.004270 0.99400
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS 53 9.73e-01 0.002660 0.99400
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS 24 9.74e-01 -0.003910 0.99400
REACTOME P75NTR REGULATES AXONOGENESIS 9 9.74e-01 -0.006300 0.99400
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS 55 9.74e-01 0.002500 0.99400
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS 77 9.75e-01 -0.002100 0.99400
REACTOME FRUCTOSE CATABOLISM 5 9.75e-01 0.008110 0.99400
REACTOME CLEC7A DECTIN 1 SIGNALING 97 9.75e-01 0.001830 0.99400
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS 6 9.75e-01 0.007350 0.99400
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE 17 9.75e-01 -0.004330 0.99400
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4 15 9.75e-01 0.004610 0.99400
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING 5 9.76e-01 0.007930 0.99400
REACTOME SLC TRANSPORTER DISORDERS 94 9.76e-01 -0.001810 0.99400
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS 122 9.76e-01 0.001590 0.99400
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH 9 9.76e-01 0.005790 0.99400
REACTOME HYALURONAN METABOLISM 17 9.76e-01 0.004170 0.99400
REACTOME CHAPERONE MEDIATED AUTOPHAGY 20 9.78e-01 -0.003550 0.99500
REACTOME SPERM MOTILITY AND TAXES 9 9.79e-01 -0.004990 0.99500
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3 11 9.80e-01 0.004460 0.99500
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES 15 9.80e-01 0.003780 0.99500
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE 20 9.80e-01 0.003160 0.99500
REACTOME REGULATION OF NPAS4 GENE EXPRESSION 13 9.81e-01 -0.003870 0.99500
REACTOME FATTY ACYL COA BIOSYNTHESIS 36 9.81e-01 0.002240 0.99500
REACTOME COMPLEMENT CASCADE 54 9.82e-01 -0.001800 0.99500
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER 81 9.85e-01 -0.001230 0.99600
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA 115 9.85e-01 0.001010 0.99600
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE 6 9.85e-01 -0.004330 0.99600
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS 15 9.86e-01 -0.002690 0.99600
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC 26 9.86e-01 0.001970 0.99600
REACTOME INACTIVATION OF CDC42 AND RAC1 8 9.87e-01 -0.003310 0.99700
REACTOME NOD1 2 SIGNALING PATHWAY 33 9.88e-01 -0.001530 0.99700
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS 7 9.89e-01 0.003040 0.99700
REACTOME PROPIONYL COA CATABOLISM 5 9.91e-01 -0.002890 0.99800
REACTOME TYROSINE CATABOLISM 5 9.92e-01 -0.002560 0.99800
REACTOME CHYLOMICRON REMODELING 10 9.92e-01 0.001770 0.99800
REACTOME NECTIN NECL TRANS HETERODIMERIZATION 7 9.93e-01 0.001810 0.99800
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX 8 9.94e-01 0.001570 0.99800
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI 26 9.94e-01 0.000870 0.99800
REACTOME LINOLEIC ACID LA METABOLISM 7 9.95e-01 0.001340 0.99800
REACTOME SCAVENGING OF HEME FROM PLASMA 13 9.95e-01 0.000965 0.99800
REACTOME REGULATION OF BETA CELL DEVELOPMENT 41 9.96e-01 -0.000440 0.99800
REACTOME ENDOGENOUS STEROLS 26 9.96e-01 0.000535 0.99800
REACTOME ONCOGENIC MAPK SIGNALING 79 9.97e-01 -0.000262 0.99800
REACTOME NEPHRIN FAMILY INTERACTIONS 22 9.97e-01 0.000438 0.99800
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE 5 9.97e-01 0.000891 0.99800
REACTOME COHESIN LOADING ONTO CHROMATIN 8 9.99e-01 -0.000261 0.99900


Detailed Gene set reports



REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION

REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
151
set REACTOME_EUKARYOTIC_TRANSLATION_ELONGATION
setSize 87
pANOVA 1.56e-06
s.dist 0.298
p.adjustANOVA 0.00207



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
EEF1A2 8084.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
EEF1A2 8084.0
EEF2 8075.0
RPL34 8063.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
EEF1B2 7682.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
RPS3A 7064.0
RPL5 7045.0
RPL32 6495.0
RPL37 6049.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
EEF1G 4746.0
RPS10 4677.0
RPS15A 4661.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPL14 2956.0
RPL38 2950.0
RPS21 2267.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
EEF1A1 1448.0
RPL36 1314.0
RPL26 455.0
FAU 437.0
RPL28 128.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
RPL41 -1150.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
RPS27L -3101.0
RPL19 -3774.0
RPS23 -3882.0
RPS27 -6223.0
RPL30 -7243.0
RPL29 -7404.0
EEF1D -7511.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
RPS26 -9575.0
RPL10L -10035.0


REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY

REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
1486
set REACTOME_RESPONSE_OF_EIF2AK4_GCN2_TO_AMINO_ACID_DEFICIENCY
setSize 94
pANOVA 2.52e-06
s.dist 0.281
p.adjustANOVA 0.00207



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
CEBPG 8919.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
CEBPG 8919.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
EIF2S1 8154.0
RPS15 8112.0
RPL34 8063.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
ATF4 7691.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
RPS3A 7064.0
RPL5 7045.0
RPL32 6495.0
DDIT3 6149.0
RPL37 6049.0
ATF2 5785.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
IMPACT 4757.0
RPS10 4677.0
RPS15A 4661.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPL14 2956.0
RPL38 2950.0
ASNS 2429.0
RPS21 2267.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
RPL36 1314.0
RPL26 455.0
FAU 437.0
RPL28 128.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
RPL41 -1150.0
CEBPB -1216.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
ATF3 -2172.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
RPS27L -3101.0
RPL19 -3774.0
RPS23 -3882.0
EIF2AK4 -4066.0
RPS27 -6223.0
RPL30 -7243.0
RPL29 -7404.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
TRIB3 -9353.0
RPS26 -9575.0
GCN1 -9946.0
RPL10L -10035.0


REACTOME_EUKARYOTIC_TRANSLATION_INITIATION

REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
1149
set REACTOME_EUKARYOTIC_TRANSLATION_INITIATION
setSize 110
pANOVA 2.83e-05
s.dist 0.231
p.adjustANOVA 0.0123



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
EIF2S1 8154.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
EIF2S1 8154.0
RPS15 8112.0
RPL34 8063.0
EIF4G1 7992.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
EIF4A1 7104.0
RPS3A 7064.0
RPL5 7045.0
RPL32 6495.0
EIF5B 6294.0
RPL37 6049.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
EIF4A2 4942.0
EIF3E 4934.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
EIF4H 4356.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
EIF3I 3026.0
RPL14 2956.0
RPL38 2950.0
EIF2B1 2554.0
RPS21 2267.0
PABPC1 2008.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
RPL36 1314.0
EIF3J 499.0
RPL26 455.0
FAU 437.0
RPL28 128.0
EIF3L -197.0
EIF4E -316.0
RPS16 -365.0
EIF4B -397.0
RPS27A -409.0
RPL37A -651.0
EIF2B2 -769.0
EIF2B4 -1008.0
RPL41 -1150.0
EIF3A -1255.0
EIF3F -1373.0
RPL17 -1554.0
EIF3D -1713.0
RPS13 -1714.0
EIF3M -1717.0
RPL18A -1756.0
RPL10A -1862.0
RPS11 -2454.0
EIF3G -2455.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
RPS27L -3101.0
EIF2B3 -3286.0
EIF2B5 -3343.0
RPL19 -3774.0
EIF3B -3790.0
RPS23 -3882.0
EIF3K -4513.0
RPS27 -6223.0
EIF3H -6415.0
EIF5 -7150.0
RPL30 -7243.0
RPL29 -7404.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
RPS26 -9575.0
EIF4EBP1 -9694.0
RPL10L -10035.0


REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE

REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
271
set REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
setSize 105
pANOVA 3e-05
s.dist 0.236
p.adjustANOVA 0.0123



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
SRPRA 9193.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
SRPRA 9193.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
RPS6 7877.0
SPCS1 7833.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
SRP14 7077.0
RPS3A 7064.0
RPL5 7045.0
SEC61B 6867.0
RPL32 6495.0
RPL37 6049.0
TRAM1 5668.0
SRP72 5421.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
SEC61G 4455.0
SPCS3 4372.0
SSR1 3939.0
RPL21 3866.0
RPLP1 3770.0
SRP54 3696.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPL14 2956.0
RPL38 2950.0
SSR3 2591.0
RPS21 2267.0
RPN2 1932.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
RPL36 1314.0
RPL26 455.0
FAU 437.0
SRP19 246.0
RPL28 128.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
RPL41 -1150.0
SSR2 -1164.0
SEC61A1 -1197.0
SEC11A -1488.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
RPS27L -3101.0
RPL19 -3774.0
RPS23 -3882.0
RPN1 -3957.0
SRP9 -4308.0
SRPRB -5909.0
RPS27 -6223.0
SPCS2 -6351.0
SRP68 -6528.0
RPL30 -7243.0
SEC11C -7287.0
RPL29 -7404.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
SEC61A2 -9358.0
RPS26 -9575.0
RPL10L -10035.0
DDOST -10369.0


REACTOME_INTERLEUKIN_10_SIGNALING

REACTOME_INTERLEUKIN_10_SIGNALING
1039
set REACTOME_INTERLEUKIN_10_SIGNALING
setSize 43
pANOVA 4.38e-05
s.dist 0.36
p.adjustANOVA 0.0123



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL22 10699
CCR2 10497
CSF3 10428
FCER2 10312
TNF 10196
CCR1 10150
CD86 9958
CCR5 9950
IL10 9658
CD80 9595
CSF2 9353
TNFRSF1A 8729
PTAFR 8009
IL1RN 7985
TNFRSF1B 7459
IL1R2 6825
CXCL8 6444
CCL2 6126
JAK1 5648
CCL19 5571

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL22 10699
CCR2 10497
CSF3 10428
FCER2 10312
TNF 10196
CCR1 10150
CD86 9958
CCR5 9950
IL10 9658
CD80 9595
CSF2 9353
TNFRSF1A 8729
PTAFR 8009
IL1RN 7985
TNFRSF1B 7459
IL1R2 6825
CXCL8 6444
CCL2 6126
JAK1 5648
CCL19 5571
IL10RB 5517
PTGS2 5394
IL1A 5386
CCL20 4752
IL6 4176
CCL4 3862
IL1B 3281
IL12A 3030
IL12B 2575
IL18 2564
ICAM1 2270
IL1R1 -13
CCL5 -22
STAT3 -2059
CSF1 -2251
IL10RA -3227
CXCL2 -3476
FPR1 -4659
CCL3 -5596
TYK2 -7461
CXCL1 -7661
CXCL10 -9659
LIF -10190


REACTOME_NONSENSE_MEDIATED_DECAY_NMD

REACTOME_NONSENSE_MEDIATED_DECAY_NMD
1443
set REACTOME_NONSENSE_MEDIATED_DECAY_NMD
setSize 107
pANOVA 4.48e-05
s.dist 0.228
p.adjustANOVA 0.0123



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
EIF4G1 7992.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
RPS3A 7064.0
RPL5 7045.0
UPF1 6659.0
RPL32 6495.0
RPL37 6049.0
PPP2CA 5736.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
SMG6 4273.0
RPL21 3866.0
SMG1 3839.0
RPLP1 3770.0
SMG8 3710.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
NCBP2 3349.0
RPS14 3317.0
GSPT1 3260.0
RPL14 2956.0
RPL38 2950.0
PPP2R1A 2659.0
RBM8A 2326.0
RPS21 2267.0
SMG7 2175.0
PABPC1 2008.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
RPL36 1314.0
UPF3A 752.0
PPP2R2A 710.0
RPL26 455.0
FAU 437.0
RPL28 128.0
UPF2 -293.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
RPL41 -1150.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
CASC3 -2082.0
ETF1 -2383.0
DCP1A -2428.0
RPS11 -2454.0
PNRC2 -2457.0
RPL26L1 -2590.0
RPS9 -2591.0
SMG5 -2682.0
RPLP0 -2913.0
RPS27L -3101.0
RNPS1 -3387.0
RPL19 -3774.0
RPS23 -3882.0
NCBP1 -4344.0
MAGOH -5117.0
RPS27 -6223.0
RPL30 -7243.0
EIF4A3 -7272.0
RPL29 -7404.0
MAGOHB -7473.0
RPS20 -8058.0
SMG9 -8106.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
RPS26 -9575.0
RPL10L -10035.0


REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
1161
set REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION
setSize 1336
pANOVA 0.000124
s.dist 0.0626
p.adjustANOVA 0.029



Top enriched genes

Top 20 genes
GeneID Gene Rank
ZNF676 10734
ZNF439 10670
RORC 10626
ZNF300 10551
SFN 10541
ZNF320 10418
ZNF562 10401
RGCC 10167
CR1 10120
MSTN 10079
HDAC5 10058
AGRP 10052
NR2C2AP 10031
ZNF100 10008
H2BC3 9932
TEAD2 9922
ZNF596 9907
BLK 9889
CGB5 9874
SRSF1 9830

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
ZNF676 10734.0
ZNF439 10670.0
RORC 10626.0
ZNF300 10551.0
SFN 10541.0
ZNF320 10418.0
ZNF562 10401.0
RGCC 10167.0
CR1 10120.0
MSTN 10079.0
HDAC5 10058.0
AGRP 10052.0
NR2C2AP 10031.0
ZNF100 10008.0
H2BC3 9932.0
TEAD2 9922.0
ZNF596 9907.0
BLK 9889.0
CGB5 9874.0
SRSF1 9830.0
SPI1 9818.0
PF4 9810.0
MIR137 9731.0
L3MBTL1 9715.0
ZNF595 9710.0
ZNF483 9699.0
ZNF385A 9682.0
ZKSCAN4 9663.0
ZNF70 9618.0
ZNF552 9614.0
ZNF597 9607.0
NPPA 9594.0
ZNF77 9514.0
MED31 9511.0
MYBL2 9504.0
ZNF786 9503.0
NR4A1 9496.0
ZNF747 9483.0
ZNF506 9462.0
THOC6 9437.0
PARP1 9435.0
CDKN2B 9418.0
ZNF470 9400.0
ZNF543 9388.0
USP2 9355.0
CSF2 9353.0
PSMD12 9352.0
PLK3 9351.0
ZNF782 9346.0
MIR27A 9345.0
MIR24-2 9328.0
PTPN1 9290.0
FASLG 9288.0
ZNF570 9274.0
ZNF205 9238.0
CTSV 9232.0
SP7 9212.0
AGO1 9204.0
MED26 9161.0
DDIT4 9133.0
ZNF660 9126.0
ZNF569 9115.0
ZNF18 9111.0
ZNF620 9079.0
ZNF214 9059.0
BID 8965.0
TRIAP1 8952.0
ZNF211 8936.0
ZNF737 8932.0
ITGA5 8926.0
TACO1 8924.0
ZNF169 8922.0
PSMB10 8921.0
IL2RA 8914.0
ZNF749 8904.0
ZNF431 8899.0
TAF12 8890.0
NR4A2 8887.0
SMARCE1 8822.0
ZNF860 8817.0
CDK13 8810.0
TCF7 8803.0
ZNF703 8775.0
NR1D1 8764.0
ZNF607 8721.0
ZNF585A 8702.0
NR4A3 8600.0
ZNF791 8571.0
ZNF443 8567.0
RARA 8562.0
FOXG1 8545.0
RBPJ 8543.0
ZNF334 8540.0
ZNF675 8529.0
SKIC8 8511.0
ZNF285 8478.0
MED4 8467.0
ZNF689 8456.0
YWHAH 8448.0
ZNF17 8416.0
PSMD4 8409.0
HEY1 8403.0
CBX5 8400.0
TNKS1BP1 8399.0
RUNX3 8397.0
ERBB2 8390.0
SLC2A3 8386.0
VDR 8368.0
PSMC1 8362.0
COX6A1 8357.0
TAF6 8354.0
RAD9B 8347.0
ZNF641 8291.0
KMT2E 8281.0
ANAPC16 8252.0
CCNB1 8226.0
TAF11 8208.0
ZNF585B 8201.0
ZNF551 8191.0
ZNF337 8166.0
H3C3 8144.0
ZNF485 8093.0
COX11 8089.0
ZFP69B 8068.0
DDX39B 8017.0
SNAPC5 8008.0
EAF2 7993.0
PERP 7981.0
CCNA1 7980.0
ZNF761 7978.0
ZNF624 7959.0
FBXO32 7916.0
SNRPF 7911.0
PAPOLA 7908.0
MEF2C 7901.0
ZNF354A 7895.0
KAT2A 7875.0
LSM11 7860.0
YBX1 7837.0
COX6B1 7830.0
UBA52 7820.0
RYBP 7805.0
ZNF670 7800.0
YWHAZ 7793.0
RNU4ATAC 7790.0
ZNF716 7781.0
H4C3 7780.0
SMARCC1 7778.0
ZNF584 7772.0
CHEK1 7747.0
ZNF415 7727.0
TNFRSF10A 7704.0
RPA3 7701.0
SYMPK 7698.0
ZNF571 7697.0
RNU11 7683.0
ZNF726 7669.0
DLL1 7665.0
RFFL 7663.0
USP7 7653.0
LEF1 7606.0
NR6A1 7559.0
RPA2 7530.0
ACTL6A 7494.0
DAXX 7463.0
G6PC1 7448.0
ZNF350 7391.0
ZNF254 7387.0
AGO4 7383.0
POMC 7382.0
ZNF668 7380.0
TBP 7375.0
PSMC6 7360.0
HES1 7356.0
FANCD2 7340.0
PSMB7 7322.0
ZNF225 7320.0
OCLN 7307.0
PSMB1 7304.0
ZNF446 7296.0
PSME2 7282.0
ZNF696 7278.0
CDC73 7273.0
ZNF222 7272.0
ELOC 7268.0
POU2F2 7248.0
PSMB3 7246.0
ZNF37A 7231.0
PSMA1 7230.0
MED7 7210.0
SMARCD2 7209.0
ARID1A 7208.0
ZNF692 7206.0
SRSF7 7205.0
INTS6 7195.0
ELF2 7194.0
ZNF662 7189.0
ZNF625 7175.0
NDUFA4 7152.0
CDK5 7122.0
ZNF713 7094.0
INTS2 7075.0
HEY2 7051.0
TCF7L2 7043.0
ZNF718 7039.0
ZNF790 7037.0
ZNF565 7016.0
CAMK2G 7003.0
COX5A 6984.0
YAP1 6969.0
ZNF688 6951.0
SKP1 6937.0
NR1I3 6908.0
CAV1 6906.0
CDC26 6899.0
ZNF112 6887.0
H3-3A 6884.0
ZFP14 6873.0
ZNF540 6817.0
POLR2D 6812.0
ZNF582 6808.0
ZNF253 6803.0
RRAGD 6794.0
ZNF701 6792.0
TCF12 6781.0
ITCH 6780.0
PSMC5 6773.0
CLP1 6723.0
GAD2 6712.0
ZKSCAN7 6702.0
CDK2 6661.0
ZNF274 6647.0
SNRPD3 6621.0
HDAC11 6605.0
THRA 6604.0
SOX9 6591.0
MNAT1 6582.0
ZNF792 6555.0
MYC 6530.0
RXRG 6524.0
PSMD1 6519.0
TP53RK 6517.0
ZNF490 6502.0
TWIST1 6498.0
CITED2 6496.0
PCNA 6481.0
ZNF529 6452.0
H3C8 6449.0
ZNF440 6440.0
ZNF420 6434.0
POU4F2 6433.0
ZNF268 6426.0
BRIP1 6425.0
ZNF180 6422.0
PIP4K2A 6410.0
PRDX2 6369.0
ZNF442 6365.0
ZNF606 6355.0
NR1I2 6315.0
ZNF304 6292.0
RNMT 6261.0
ZNF697 6249.0
BTG2 6247.0
GAMT 6211.0
HDAC1 6190.0
ZNF215 6185.0
SST 6173.0
POU2F1 6163.0
DDIT3 6149.0
ANAPC10 6093.0
ZNF573 6084.0
TFAP2A 6059.0
ZNF333 6054.0
H4C1 6046.0
LDB1 6040.0
E2F8 6018.0
NUDT21 6008.0
RBM14 5992.0
MED6 5982.0
TAF7 5964.0
PCF11 5956.0
RORB 5943.0
ZNF235 5937.0
HUS1 5924.0
DYRK2 5917.0
ZNF221 5898.0
SCO1 5880.0
ZNF793 5867.0
GTF2A2 5861.0
PHC1 5822.0
ANAPC15 5818.0
ATF2 5785.0
RBBP5 5771.0
RAD9A 5766.0
TEAD4 5750.0
PPP2CA 5736.0
SCMH1 5731.0
ZFP90 5717.0
NR2E1 5688.0
CSTF1 5674.0
MAML1 5665.0
ARID3A 5660.0
ZNF454 5652.0
ZNF248 5646.0
YAF2 5634.0
CDK4 5622.0
ZNF273 5619.0
ZKSCAN8 5577.0
CGA 5558.0
H2BC5 5548.0
RPRD1B 5524.0
DDB2 5516.0
POLR2E 5508.0
ABCA6 5492.0
SMARCB1 5488.0
TGIF1 5468.0
TCF7L1 5461.0
PIDD1 5448.0
RPRD1A 5434.0
GLS 5422.0
SRSF3 5403.0
PTPN11 5384.0
PIP4P1 5383.0
CDC40 5364.0
MED10 5357.0
SMARCD3 5355.0
TGIF2 5347.0
RUNX2 5335.0
HDAC7 5324.0
MED13 5315.0
ELL 5284.0
H2BC14 5277.0
COX7C 5268.0
GTF2E1 5256.0
PBRM1 5251.0
BTG1 5221.0
ZNF140 5217.0
PRR5 5200.0
ZNF710 5191.0
ASH2L 5189.0
UBB 5177.0
THRB 5171.0
PRELID1 5155.0
PSMA6 5154.0
CITED4 5140.0
CSNK2A1 5137.0
ZNF544 5132.0
FOXO3 5124.0
BRD1 5090.0
ZNF136 5080.0
ZNF626 5072.0
BRD2 5052.0
SMAD2 5036.0
ARNT 5021.0
CCNT2 5005.0
ZNF655 5000.0
ZNF736 4999.0
HDAC2 4994.0
PPP1R13L 4982.0
CCND1 4979.0
GPS2 4974.0
ZNF233 4973.0
BMI1 4950.0
PPARGC1B 4946.0
CDC25C 4930.0
GATA2 4895.0
ZNF669 4889.0
RAD50 4888.0
CPSF6 4876.0
E2F5 4875.0
TCEA1 4871.0
DGCR8 4825.0
RSPO3 4821.0
INTS12 4817.0
MGA 4791.0
PSMA3 4777.0
BCL2L11 4775.0
CCNA2 4763.0
HDAC3 4748.0
ATR 4721.0
NFYB 4719.0
GATAD2B 4713.0
ZNF775 4712.0
PRKAA1 4691.0
TFDP2 4682.0
MED24 4654.0
ZNF234 4644.0
YES1 4638.0
ZNF331 4637.0
TAF9 4562.0
POLR2I 4560.0
RFC4 4550.0
CAMK4 4542.0
TP73 4523.0
ZNF473 4496.0
LMO2 4492.0
PSMD13 4481.0
ELL2 4474.0
ZNF589 4467.0
GRIA2 4444.0
TXNIP 4432.0
ZNF616 4414.0
ZNF429 4406.0
UBE2E1 4394.0
SMAD7 4392.0
ZNF479 4361.0
MED30 4342.0
PSMD11 4322.0
SIN3A 4303.0
PSMA4 4297.0
CAMK2D 4280.0
NPM1 4266.0
H2AZ1 4233.0
SARNP 4209.0
TAF1L 4206.0
IL6 4176.0
SYT10 4136.0
MDM4 4134.0
ZNF324B 4123.0
CAT 4096.0
SKI 4092.0
ZNF613 4089.0
ZNF141 4088.0
RNF111 4064.0
ARID2 4058.0
TXN 4057.0
ZNF28 4049.0
ZNF557 4029.0
ZFP2 4026.0
H3C11 4016.0
ZNF704 4011.0
ZNF10 4007.0
E2F1 4006.0
ZNF267 3980.0
SKP2 3979.0
CHEK2 3977.0
ZNF568 3954.0
ZNF740 3941.0
PPARG 3905.0
ZNF528 3893.0
INTS10 3873.0
TAF2 3842.0
ZNF79 3833.0
FOS 3811.0
H2BC10 3801.0
JUN 3797.0
CSF1R 3766.0
MAPK11 3753.0
ZC3H8 3724.0
ZFP30 3719.0
KCTD1 3706.0
SOX2 3705.0
SUPT5H 3692.0
PSMC4 3690.0
SOD2 3662.0
RAD17 3650.0
ZNF432 3647.0
RPAP2 3644.0
ZNF460 3619.0
CDKN1A 3616.0
WRN 3608.0
NDRG1 3597.0
RBBP4 3586.0
DLX6 3578.0
ZFP69 3571.0
SESN2 3568.0
YEATS4 3565.0
ZNF621 3543.0
TRPC3 3542.0
BRCA1 3510.0
ZFPM1 3422.0
CBX3 3415.0
PSMA7 3408.0
PLXNA4 3391.0
E2F7 3367.0
TFAP2D 3365.0
NPY 3359.0
NCBP2 3349.0
RMI1 3338.0
CAMK2A 3300.0
ZNF721 3280.0
ZNF398 3278.0
PSMA8 3274.0
ZNF556 3215.0
CPSF2 3200.0
ZNF671 3197.0
ATM 3165.0
PITX2 3142.0
WDR33 3141.0
DPY30 3136.0
CSTF2T 3125.0
ZNF583 3122.0
MET 3117.0
E2F4 3106.0
MSH2 3104.0
MOBP 3073.0
LSM10 3070.0
ZNF665 3062.0
RBBP8 3047.0
MYB 3028.0
YWHAG 3022.0
H4C8 3010.0
HIVEP3 2977.0
SUZ12 2965.0
JMY 2963.0
RXRA 2936.0
H4C11 2849.0
ZNF567 2847.0
NR1H3 2807.0
TAF5 2803.0
ZNF804B 2802.0
PMAIP1 2781.0
APAF1 2773.0
PRMT5 2766.0
LAMTOR3 2763.0
CCNG1 2759.0
ING2 2758.0
CDKN1B 2756.0
ZNF681 2743.0
NR2C1 2722.0
ZNF430 2702.0
ZNF517 2680.0
PAX5 2666.0
PPP2R1A 2659.0
ZNF226 2654.0
SRSF11 2649.0
JAG1 2647.0
CDK8 2641.0
GTF2H4 2630.0
SNAPC1 2610.0
ANAPC5 2600.0
FYTTD1 2592.0
TAF13 2589.0
SETD1B 2578.0
CBX4 2532.0
ANAPC4 2522.0
LAMTOR2 2473.0
ZNF549 2463.0
BRPF1 2462.0
NCOR1 2444.0
PPARGC1A 2433.0
GATAD2A 2417.0
ANAPC7 2402.0
ESR1 2393.0
PMS2 2385.0
XPO1 2379.0
SESN1 2361.0
TEAD3 2357.0
RBM8A 2326.0
ZNF461 2316.0
CENPJ 2288.0
ZNF224 2271.0
ITGA2B 2256.0
UBE2C 2235.0
CTSK 2233.0
PRKAB1 2222.0
PRDM1 2185.0
PSMB5 2174.0
PRKAG2 2173.0
AIFM2 2165.0
PPP1R13B 2162.0
ZNF510 2161.0
ZNF496 2157.0
NAMPT 2140.0
ZNF566 2134.0
RAD51D 2071.0
LMO1 2070.0
MED23 2047.0
ZNF559 2037.0
NR1D2 2033.0
TFAP2B 2028.0
PRKCQ 1992.0
CNOT4 1978.0
INTS8 1975.0
ZNF25 1956.0
SRF 1955.0
RORA 1893.0
SUPT6H 1892.0
ZNF555 1885.0
UBC 1879.0
H2AZ2 1833.0
NELFCD 1815.0
ZNF417 1812.0
ICE1 1809.0
RBX1 1772.0
GAD1 1765.0
CREB1 1764.0
SNW1 1745.0
EZH2 1739.0
SMAD6 1726.0
RRAGC 1719.0
COX8A 1703.0
TBX5 1672.0
THOC5 1665.0
GRIN2A 1632.0
TTC5 1623.0
H2BC17 1606.0
RABGGTB 1596.0
UCMA 1588.0
RMI2 1570.0
ZNF560 1552.0
RAD1 1533.0
H2AC14 1530.0
RFC3 1529.0
SMAD3 1511.0
CNOT8 1483.0
ZSCAN25 1475.0
H4C13 1450.0
SEM1 1440.0
AGO2 1431.0
ITGA4 1423.0
ZNF311 1421.0
PHAX 1401.0
BRPF3 1398.0
ZNF155 1394.0
LRPPRC 1389.0
GATA4 1309.0
EAF1 1306.0
PSMD3 1303.0
TNRC6B 1301.0
NFYC 1279.0
H2BC15 1278.0
NR0B2 1267.0
ZNF2 1265.0
ZNF175 1261.0
PLAGL1 1245.0
NELFB 1221.0
CYCS 1219.0
EXO1 1214.0
ACTL6B 1199.0
AURKB 1188.0
PRELID3A 1184.0
ZNF208 1158.0
ZNF302 1156.0
SATB2 1111.0
GLS2 1097.0
SERPINE1 1090.0
POLR2F 1076.0
MLH1 1068.0
RABGGTA 1066.0
ELL3 1065.0
H3-3B 1057.0
MED27 1054.0
FBXW7 1047.0
TFAP2C 1035.0
ZNF709 1028.0
ZNF184 1021.0
CNOT7 1009.0
ZNF577 995.0
CCNC 991.0
TXNRD1 984.0
AGO3 977.0
POLR2K 936.0
PPM1A 894.0
ZIK1 850.0
MAML3 847.0
TNFRSF10B 843.0
MAML2 840.0
TRIM28 835.0
WWTR1 827.0
ZNF519 808.0
NR3C2 804.0
ESR2 800.0
REST 787.0
CCND2 784.0
H4C6 772.0
ZNF658 708.0
HDAC10 704.0
ZNF34 702.0
BMP2 640.0
ZNF546 630.0
ELOA2 629.0
PSME3 614.0
COX19 600.0
HIPK2 583.0
ZNF19 568.0
ZNF436 566.0
MED16 553.0
INTS7 545.0
IHH 527.0
CDC23 522.0
PSMD6 518.0
CBX8 508.0
CCNH 498.0
INTS5 474.0
KIT 446.0
SP1 444.0
ZNF135 443.0
PPARD 421.0
GPAM 402.0
KMT5A 392.0
ZNF486 371.0
COL1A1 355.0
RARB 344.0
KRBA1 326.0
LEO1 314.0
ZNF394 301.0
FANCC 288.0
H2AJ 281.0
TAF15 260.0
HDAC4 241.0
RBL2 224.0
MLLT3 208.0
PHC3 197.0
IWS1 141.0
POU4F1 126.0
ZNF223 120.0
PSMD14 114.0
RARG 107.0
MDM2 76.0
ZNF227 71.0
SNAPC3 12.0
CCNK -35.0
ZNF282 -61.0
PAF1 -92.0
CDC16 -139.0
CRADD -162.0
NOTCH4 -182.0
NBN -196.0
CCND3 -220.0
ZNF230 -250.0
ZNF154 -267.0
YWHAQ -284.0
ZNF30 -292.0
PLK2 -320.0
PVALB -334.0
POLR2L -338.0
KCTD15 -364.0
AKT1 -370.0
ZNF160 -390.0
ZNF678 -393.0
PRKAB2 -395.0
H4C16 -406.0
ZNF286A -408.0
RPS27A -409.0
ZNF101 -411.0
NR3C1 -420.0
MED25 -427.0
GTF2B -435.0
ZNF773 -446.0
PRKCB -450.0
ZNF547 -475.0
SREBF1 -476.0
MLLT1 -498.0
PCGF6 -530.0
GRIN2B -540.0
H4C4 -548.0
STUB1 -563.0
ZNF26 -585.0
KAT6A -597.0
ZNF200 -607.0
BDNF -618.0
TPX2 -619.0
ZNF382 -620.0
ZNF14 -636.0
KMT2D -642.0
SGK1 -662.0
PCGF2 -667.0
GTF2F2 -676.0
SMAD1 -731.0
ZFP1 -741.0
GEM -758.0
PPP2R5C -775.0
ZNF75A -785.0
COX16 -799.0
ZNF250 -810.0
CPSF3 -844.0
PTPN4 -845.0
BARD1 -852.0
TP53I3 -874.0
ZNF99 -876.0
RNF34 -877.0
RPTOR -890.0
SRSF6 -895.0
PTEN -898.0
THBS1 -911.0
ZNF492 -912.0
MAPKAP1 -919.0
RET -923.0
AURKA -927.0
SRRT -929.0
COL1A2 -946.0
RPRD2 -950.0
ZNF611 -952.0
SERPINB13 -971.0
NPAS4 -972.0
PCK1 -978.0
ZNF586 -1006.0
SPP1 -1056.0
EPC1 -1063.0
BNIP3L -1078.0
TSC1 -1098.0
UBE2D3 -1117.0
BGLAP -1161.0
ZNF324 -1183.0
PRDX5 -1188.0
NR5A1 -1196.0
CEBPB -1216.0
CBFB -1228.0
SETD9 -1230.0
CDK1 -1231.0
ZNF347 -1232.0
CTSL -1259.0
ZNF416 -1265.0
PSMD5 -1267.0
GSK3B -1274.0
H4C12 -1288.0
NOTCH3 -1289.0
ATAD2 -1302.0
POLR2C -1312.0
NR5A2 -1323.0
PPM1D -1338.0
HSPD1 -1342.0
SRSF5 -1346.0
ZNF776 -1353.0
NABP1 -1356.0
COX7A2L -1368.0
PSMB4 -1390.0
TJP1 -1403.0
NOTCH2 -1450.0
YWHAB -1452.0
ZNF530 -1469.0
SNAPC2 -1490.0
CSTF3 -1502.0
MED20 -1518.0
ZNF514 -1545.0
GTF2H3 -1549.0
ZNF213 -1566.0
MSX2 -1591.0
BAX -1601.0
SESN3 -1613.0
ZNF264 -1619.0
ZNF750 -1635.0
NEDD4L -1653.0
MDC1 -1656.0
SSRP1 -1660.0
NFKB1 -1676.0
HDAC9 -1694.0
PRDM7 -1704.0
ZNF143 -1706.0
CARM1 -1720.0
CCNG2 -1754.0
H4C2 -1760.0
VEGFA -1763.0
ZNF114 -1775.0
ZNF839 -1779.0
MAPK1 -1793.0
ZNF610 -1802.0
ZKSCAN1 -1812.0
DLX5 -1905.0
CNOT11 -1913.0
COX14 -1933.0
NR2F6 -1934.0
POLR2B -1946.0
TCF3 -1955.0
ZNF691 -1981.0
ZNF195 -1999.0
ZNF266 -2016.0
RRM2B -2024.0
H2AC18 -2027.5
H2AC19 -2027.5
ZNF770 -2037.0
ZNF714 -2039.0
GTF2E2 -2058.0
ZC3H11A -2081.0
CASC3 -2082.0
INTS4 -2122.0
DNA2 -2127.0
BLM -2129.0
BANP -2136.0
RPA1 -2156.0
SMARCC2 -2182.0
CHTOP -2208.0
SMARCD1 -2223.0
CDKN2A -2235.0
GCK -2237.0
CDC27 -2268.0
HNF4A -2279.0
GTF2H1 -2280.0
SMARCA2 -2288.0
SUPT4H1 -2295.0
ZNF426 -2311.0
GTF2A1 -2347.0
TP53INP1 -2350.0
MAPK14 -2356.0
KMT2C -2380.0
EHMT1 -2439.0
ANAPC11 -2493.0
PIN1 -2502.0
SMARCA4 -2517.0
ARNT2 -2559.0
RXRB -2571.0
AUTS2 -2575.0
ZFP28 -2578.0
WWP1 -2604.0
SRC -2605.0
NABP2 -2629.0
CDK7 -2633.0
INTS3 -2640.0
TFAP2E -2660.0
PRKAA2 -2684.0
PRMT6 -2699.0
GPRIN1 -2714.0
GTF2H5 -2723.0
ELF1 -2742.0
ZNF727 -2752.0
ZNF263 -2772.0
ZNF778 -2804.0
POLR2H -2828.0
RB1 -2851.0
INTS9 -2859.0
ZNF124 -2865.0
LAMTOR5 -2866.0
H2AC4 -2892.0
ZKSCAN5 -2898.0
ZNF875 -2899.0
RUNX1 -2900.0
ATXN3 -2943.0
CASP10 -2955.0
ARID1B -2980.0
ZNF667 -2990.0
PSMD7 -3011.0
E2F6 -3037.0
BCL6 -3062.0
HAND2 -3070.0
SUPT16H -3076.0
TGFB1 -3077.0
GTF2F1 -3086.0
KLF4 -3097.0
NR1H2 -3115.0
ZNF564 -3127.0
THOC1 -3149.0
RHEB -3154.0
CHD4 -3171.0
TP53 -3175.0
PSMB8 -3188.0
HIPK1 -3197.0
ZNF45 -3217.0
RFC2 -3235.0
ZNF772 -3268.0
FOXO6 -3278.0
H3C1 -3282.0
ZNF23 -3328.0
CUL1 -3367.0
ZNF433 -3368.0
AKT3 -3379.0
RNPS1 -3387.0
ZNF614 -3394.0
POLR2G -3408.0
L3MBTL2 -3440.0
KMT2A -3441.0
WWOX -3444.0
ZNF615 -3467.0
H2BC1 -3496.0
ZNF500 -3507.0
NFATC2 -3514.0
NCOR2 -3557.0
PHF20 -3563.0
PRDX1 -3574.0
PRKAG3 -3579.0
MAP2K6 -3585.0
ESRRA -3626.0
ZNF287 -3646.0
BMAL1 -3650.0
ZNF189 -3656.0
MTA2 -3687.0
PHC2 -3689.0
LGALS3 -3691.0
NUAK1 -3692.0
SKIL -3700.0
PSMB9 -3719.0
SIN3B -3734.0
CALM1 -3759.0
CASP1 -3763.0
UBE2S -3764.0
ZNF677 -3766.0
HNF4G -3768.0
ZNF133 -3777.0
CHD3 -3786.0
AXIN1 -3805.0
PSMD8 -3830.0
ESRRG -3886.0
STAT1 -3915.0
PML -3934.0
FANCI -3936.0
ZNF771 -3943.0
COX20 -3948.0
CSNK2B -3971.0
INTS13 -3985.0
PCGF5 -4000.0
YY1 -4050.0
CTLA4 -4073.0
MIR132 -4085.0
ZNF706 -4089.0
ZNF563 -4091.0
PGR -4107.0
ZNF471 -4115.0
GADD45A -4144.0
RNGTT -4154.0
CPSF1 -4172.0
PINK1 -4184.0
ZNF202 -4243.0
ZNF664 -4254.0
PABPN1 -4270.0
TNRC6C -4307.0
NFYA -4335.0
RAD51 -4338.0
NCBP1 -4344.0
CDK6 -4345.0
CSNK2A2 -4372.0
CBX6 -4376.0
PPARA -4380.0
RETN -4384.0
ZNF599 -4403.0
RNU12 -4408.0
ABL1 -4417.0
SLC38A9 -4430.0
ZIM3 -4485.0
BBC3 -4511.0
CAMK2B -4518.0
ZNF468 -4519.0
ZNF700 -4527.0
EHMT2 -4529.0
ITGAL -4551.0
TOP3A -4562.0
TNRC6A -4567.0
ZNF33A -4597.0
COX6C -4603.0
H2BC21 -4612.0
SOCS4 -4628.0
CNOT9 -4656.0
ZNF343 -4676.0
ICE2 -4692.0
TIGAR -4693.0
PSMC3 -4708.0
PPP2R1B -4709.0
ZNF445 -4720.0
ZNF257 -4732.0
RRAGA -4743.0
FIP1L1 -4745.0
DEK -4758.0
COX18 -4779.0
MAX -4795.0
CDK12 -4803.0
NOP2 -4806.0
IFNG -4820.0
TP63 -4834.0
ZNF724 -4841.0
CNOT6L -4863.0
TOPBP1 -4868.0
TGFA -4899.0
CCN2 -4925.0
RBL1 -4940.0
MAPKAPK5 -4954.0
ZNF649 -4974.0
PIP4K2C -4979.0
PCBP4 -4992.0
H3C4 -4999.0
UBE2I -5025.0
SMURF2 -5027.0
CNOT10 -5034.0
FOXO1 -5042.0
VENTX -5066.0
SNAPC4 -5112.0
MAGOH -5117.0
MRE11 -5146.0
ZNF627 -5148.0
MYL9 -5185.0
CNOT3 -5188.0
IGFBP3 -5202.0
KCTD6 -5256.0
EED -5263.0
RFC5 -5282.0
OPRM1 -5288.0
ZNF738 -5295.0
SUMO1 -5346.0
MLST8 -5409.0
COX4I1 -5434.0
CASP6 -5446.0
COX5B -5464.0
INTS1 -5488.0
TSC2 -5491.0
SRSF4 -5499.0
SNRPB -5512.0
AKT2 -5525.0
CTR9 -5545.0
SRRM1 -5563.0
HTT -5572.0
ELOA -5604.0
PSMA5 -5619.0
ERCC3 -5620.0
ZNF777 -5622.0
JUNB -5643.0
CCNE1 -5650.0
NR2C2 -5655.0
TFDP1 -5684.0
RING1 -5693.0
TP53AIP1 -5695.0
H3C2 -5710.0
POLDIP3 -5737.0
LIFR -5757.0
EP300 -5781.0
H2BC4 -5800.0
PPP2CB -5808.0
CRH -5809.0
TAF10 -5815.0
PRKACA -5856.0
RBFOX3 -5923.0
H2BC6 -5925.0
ZNF493 -5928.0
CCNE2 -5933.0
ZNF3 -5946.0
STK11 -5954.0
PSME4 -6007.0
FZR1 -6019.0
ITGBL1 -6050.0
MIR24-1 -6053.0
KAT5 -6090.0
CASP2 -6094.0
NFE2 -6099.0
RICTOR -6117.0
CNOT1 -6128.0
PSMA2 -6134.0
ZNF138 -6153.0
CBX2 -6155.0
RNF2 -6179.0
PRKAG1 -6189.0
SNRPG -6195.0
NRBF2 -6200.0
H2AC7 -6206.5
H2BC7 -6206.5
KDM5B -6230.0
TAF4 -6232.0
INS -6246.0
ZNF20 -6287.0
SIRT3 -6291.0
NELFE -6369.0
ZNF785 -6393.0
NOTCH1 -6398.0
ANAPC1 -6403.0
ZNF33B -6405.0
MBD3 -6409.0
ZFHX3 -6422.0
LBR -6424.0
ZNF256 -6445.0
ZNF12 -6486.0
ZNF74 -6498.0
NR2E3 -6513.0
ZNF521 -6527.0
SLBP -6530.0
ZSCAN32 -6534.0
PSMC2 -6591.0
ZNF682 -6626.0
ALYREF -6636.0
CDC7 -6650.0
CCNT1 -6674.0
ZNF480 -6689.0
CDK5R1 -6696.0
CNOT6 -6738.0
ZNF354B -6754.0
TRIM63 -6790.0
TBL1XR1 -6802.0
RBFOX1 -6898.0
TNFRSF10D -6908.0
NOC2L -6916.0
ZNF707 -6933.0
ZNF548 -6972.0
ZNF212 -6994.0
GLI3 -6996.0
MTOR -7026.0
CNOT2 -7028.0
U2AF1L4 -7058.0
H2AC6 -7076.0
FKBP5 -7171.0
CPSF7 -7176.0
ATRIP -7183.0
SMYD2 -7259.0
PSMF1 -7266.0
EIF4A3 -7272.0
NKX3-2 -7282.0
SMURF1 -7311.0
H4C5 -7353.0
DHX38 -7362.0
SMAD4 -7376.0
TEAD1 -7394.0
H2AC8 -7412.0
TAF4B -7421.0
EGFR -7457.0
MAGOHB -7473.0
H2BC26 -7498.0
MAPK3 -7507.0
SSU72 -7515.0
H2BC13 -7520.0
GSR -7533.0
PSMD9 -7539.0
ZNF425 -7543.0
LAMTOR4 -7556.0
ZNF554 -7579.0
DDX39A -7598.0
RRM2 -7611.0
UBE2D1 -7612.0
APOE -7665.0
LAMTOR1 -7679.0
MOV10 -7718.0
GPX2 -7765.0
CREBBP -7802.0
NELFA -7853.0
ZNF799 -7866.0
PSMB2 -7879.0
CGB8 -7883.0
ZNF699 -7905.0
TNFRSF18 -7935.0
PDPK1 -7938.0
KRAS -7949.0
BCL2L14 -8013.0
ZNF746 -8042.0
H2AC20 -8060.0
INTS14 -8092.0
TAL1 -8103.0
SETD1A -8104.0
ZNF550 -8139.0
TAF3 -8204.0
IQSEC3 -8236.0
PRMT1 -8243.0
SRSF9 -8272.0
THOC7 -8280.0
BRD7 -8282.0
NR1H4 -8285.0
H2BC11 -8291.0
STEAP3 -8292.0
U2AF2 -8310.0
AFF4 -8347.0
PSMD2 -8354.0
NR2F1 -8377.0
TNFRSF10C -8405.0
ZNF600 -8410.0
ZNF684 -8422.0
ZNF729 -8423.0
RTF1 -8427.0
CTDP1 -8428.0
ELOB -8474.0
SRSF2 -8489.0
H2BC9 -8506.5
H3C7 -8506.5
KAT2B -8525.0
ZNF708 -8540.0
TMEM219 -8552.0
MED1 -8569.0
ZNF484 -8585.0
KCNIP3 -8610.0
SIRT1 -8646.0
ZKSCAN3 -8651.0
ZNF730 -8668.0
SNRPE -8673.0
TRIM33 -8674.0
H3C10 -8687.0
IGFBP1 -8691.0
PIP4K2B -8701.0
CTNNB1 -8712.0
MEN1 -8747.0
CDK9 -8753.0
MEAF6 -8764.0
MED15 -8766.0
ZNF197 -8778.0
SURF1 -8819.0
OPRK1 -8825.0
GPI -8888.0
WDR5 -8897.0
RELA -8902.0
RHNO1 -8958.0
CPSF4 -8976.0
ZNF419 -9014.0
YWHAE -9062.0
H2BC8 -9074.0
H2BC12 -9154.0
ZNF764 -9156.0
ZNF43 -9192.0
ANAPC2 -9194.0
MED8 -9310.0
ZNF418 -9317.0
SCO2 -9458.0
ZNF71 -9491.0
NRBP1 -9501.0
FAS -9507.0
GLI2 -9544.0
POLR2A -9547.0
H3C6 -9584.0
TAF8 -9585.0
MMP13 -9589.0
ESRRB -9594.0
MAF -9711.0
ERCC2 -9718.0
ZNF680 -9719.0
MED17 -9731.0
ZNF317 -9738.0
PSMB11 -9770.0
NKX2-5 -9771.0
ZNF774 -9783.0
ZNF441 -9834.0
KRBOX5 -9839.0
ZFP37 -9859.0
ZNF561 -9867.0
PSMB6 -9876.0
CLDN5 -9884.0
ZIM2 -9960.0
TP53BP2 -10073.0
ING5 -10076.0
ZNF605 -10117.0
INTS11 -10143.0
H2AX -10147.0
PSME1 -10185.0
GP1BA -10208.0
ZNF383 -10229.0
H4C9 -10234.0
ZNF587 -10263.0
ZNF558 -10303.0
ZNF92 -10308.0
GATA3 -10345.0
NLRC4 -10360.0
SOCS3 -10374.0
TWIST2 -10393.0
ZNF735 -10399.0
BIRC5 -10419.0
ZNF619 -10437.0
IL2 -10442.0
POLR2J -10455.0
SLU7 -10466.0
FURIN -10501.0
KMT2B -10571.0
ZNF354C -10599.0
H3C12 -10777.0
ZNF732 -11072.0
ZNF679 -11078.0
IL3 -11083.0
THOC3 -11185.0
ZNF717 -11190.0


REACTOME_SELENOAMINO_ACID_METABOLISM

REACTOME_SELENOAMINO_ACID_METABOLISM
484
set REACTOME_SELENOAMINO_ACID_METABOLISM
setSize 108
pANOVA 0.000195
s.dist 0.207
p.adjustANOVA 0.04



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNMT 10092.0
MAT1A 10021.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNMT 10092.0
MAT1A 10021.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
RPS3A 7064.0
RPL5 7045.0
RPL32 6495.0
RPL37 6049.0
AIMP1 5405.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
LARS1 4450.0
AHCY 4369.0
DARS1 4144.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
SEPSECS 3377.0
RPS14 3317.0
CTH 3054.0
RPL14 2956.0
RPL38 2950.0
HNMT 2735.0
PSTK 2560.0
RPS21 2267.0
SECISBP2 2238.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RPL11 1544.0
RPL36 1314.0
EPRS1 1271.0
TXNRD1 984.0
SEPHS2 767.0
RPL26 455.0
FAU 437.0
RPL28 128.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
RPL41 -1150.0
RARS1 -1308.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
KARS1 -1845.0
RPL10A -1862.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
IARS1 -3084.0
RPS27L -3101.0
RPL19 -3774.0
RPS23 -3882.0
PAPSS1 -4768.0
PAPSS2 -5232.0
EEFSEC -5252.0
EEF1E1 -6152.0
AIMP2 -6219.0
RPS27 -6223.0
INMT -6839.0
RPL30 -7243.0
RPL29 -7404.0
GSR -7533.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
MARS1 -8722.0
RPS26 -9575.0
NNMT -9653.0
SCLY -9864.0
RPL10L -10035.0


REACTOME_SIGNALING_BY_INTERLEUKINS

REACTOME_SIGNALING_BY_INTERLEUKINS
800
set REACTOME_SIGNALING_BY_INTERLEUKINS
setSize 444
pANOVA 0.000295
s.dist 0.1
p.adjustANOVA 0.0538



Top enriched genes

Top 20 genes
GeneID Gene Rank
CCL22 10699
IL23A 10658
RORC 10626
IL36G 10550
IL20 10535
RAG1 10531
CCR2 10497
LCK 10443
CSF3 10428
IL32 10423
CLCF1 10374
FCER2 10312
IL7R 10247
TNF 10196
SAA1 10186
MYD88 10180
S100A12 10170
CCR1 10150
CD86 9958
CCR5 9950

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CCL22 10699.0
IL23A 10658.0
RORC 10626.0
IL36G 10550.0
IL20 10535.0
RAG1 10531.0
CCR2 10497.0
LCK 10443.0
CSF3 10428.0
IL32 10423.0
CLCF1 10374.0
FCER2 10312.0
IL7R 10247.0
TNF 10196.0
SAA1 10186.0
MYD88 10180.0
S100A12 10170.0
CCR1 10150.0
CD86 9958.0
CCR5 9950.0
P4HB 9888.0
IL34 9850.0
IRAK2 9811.0
IL10 9658.0
CTSG 9599.0
CD80 9595.0
IL27RA 9580.0
HSP90B1 9493.0
IRF4 9439.0
IL18R1 9395.0
CSF2 9353.0
PSMD12 9352.0
IL7 9297.0
FASLG 9288.0
IL18RAP 9248.0
MUC1 9080.0
PSMB10 8921.0
IL2RA 8914.0
IL16 8883.0
CTF1 8786.0
DUSP4 8770.0
BCL2 8749.0
PIK3CD 8742.0
TNFRSF1A 8729.0
BCL2L1 8672.0
HGF 8662.0
IL21R 8626.0
GRB2 8575.0
IL17RC 8539.0
CNN2 8486.0
LYN 8472.0
USP18 8447.0
PSMD4 8409.0
PSMC1 8362.0
SNRPA1 8293.0
CBL 8272.0
DUSP3 8236.0
IL15 8198.0
H3C3 8144.0
DUSP6 8057.0
NKIRAS2 8013.0
PTAFR 8009.0
IL1RN 7985.0
IL19 7956.0
MEF2C 7901.0
HSPA8 7841.0
IL27 7822.0
UBA52 7820.0
STAT6 7801.0
YWHAZ 7793.0
IL11RA 7735.0
SYK 7703.0
CRKL 7676.0
ITGB2 7637.0
ANXA2 7581.0
PELI3 7480.0
TNFRSF1B 7459.0
IL18BP 7389.0
POMC 7382.0
PSMC6 7360.0
PSMB7 7322.0
PSMB1 7304.0
PSME2 7282.0
PSMB3 7246.0
PSMA1 7230.0
LMNB1 7218.0
RAG2 7125.0
MAP2K3 7085.0
IL25 7069.0
MAP3K8 7028.0
SKP1 6937.0
BLNK 6870.0
IL1R2 6825.0
IL12RB1 6824.0
PSMC5 6773.0
TRAF6 6579.0
MYC 6530.0
PSMD1 6519.0
PIK3R2 6512.0
TWIST1 6498.0
H3C8 6449.0
CXCL8 6444.0
SERPINB2 6370.0
IKBIP 6279.0
PELI2 6217.0
SOS2 6167.0
POU2F1 6163.0
CFL1 6160.0
CCL2 6126.0
DUSP7 6119.0
IFNLR1 5976.0
IL6ST 5928.0
BRWD1 5899.0
GSTO1 5868.0
HMGB1 5850.0
IL26 5824.0
INPP5D 5787.0
ATF2 5785.0
PPP2CA 5736.0
CEBPD 5658.0
JAK1 5648.0
IL1RAP 5606.0
CCL19 5571.0
IL10RB 5517.0
PIK3CA 5509.0
PELI1 5473.0
PTGS2 5394.0
IL1A 5386.0
PTPN11 5384.0
HCK 5351.0
UBB 5177.0
PSMA6 5154.0
PTPN18 5126.0
FOXO3 5124.0
IL1RL1 5027.0
CCND1 4979.0
SOCS1 4802.0
PSMA3 4777.0
PTK2B 4776.0
CCL20 4752.0
HIF1A 4741.0
YES1 4638.0
AIP 4634.0
N4BP1 4632.0
LBP 4617.0
MAPK7 4565.0
PSMD13 4481.0
HMOX1 4473.0
IL23R 4449.0
PSMD11 4322.0
PSMA4 4297.0
ITGAX 4294.0
TCP1 4271.0
LCP1 4223.0
PPIA 4220.0
IL12RB2 4212.0
NFKBIA 4178.0
IL6 4176.0
SHC1 4154.0
IL11 4127.0
STX1A 4126.0
MAPKAPK2 4095.0
IL15RA 4091.0
SDC1 4056.0
H3C11 4016.0
HAVCR2 3993.0
S100B 3910.0
CCL4 3862.0
PTPN6 3857.0
RIPK2 3847.0
FOS 3811.0
IL17C 3808.0
JUN 3797.0
CSF1R 3766.0
MAPK11 3753.0
IL37 3748.0
SOX2 3705.0
PSMC4 3690.0
SOD2 3662.0
CDKN1A 3616.0
PDCD4 3511.0
PSMA7 3408.0
IL1B 3281.0
PSMA8 3274.0
PTPN5 3201.0
TAB1 3094.0
SQSTM1 3052.0
IL12A 3030.0
LRRC14 2889.0
RAPGEF1 2834.0
CA1 2833.0
FSCN1 2832.0
PIK3R1 2800.0
RHOU 2790.0
IL1F10 2788.0
BTRC 2718.0
PTPN23 2694.0
PPP2R1A 2659.0
STX3 2653.0
CD36 2611.0
IL12B 2575.0
IL18 2564.0
IL4 2559.0
GAB2 2556.0
ARF1 2501.0
MAP2K1 2431.0
NKIRAS1 2377.0
ICAM1 2270.0
IL5RA 2254.0
PSMB5 2174.0
FBXW11 2151.0
MIF 2142.0
NOS2 2122.0
IL2RB 2108.0
MEF2A 2098.0
MAP3K3 2013.0
LCN2 1969.0
IL20RA 1937.0
RORA 1893.0
PTPN9 1887.0
UBC 1879.0
PTPN12 1842.0
NDN 1839.0
USP14 1773.0
RBX1 1772.0
CREB1 1764.0
CANX 1597.0
MAPK8 1549.0
SMAD3 1511.0
TEC 1500.0
SEM1 1440.0
STAT4 1407.0
IL4R 1357.0
PSMD3 1303.0
HNRNPA2B1 1168.0
IL36B 1094.0
STXBP2 948.0
IL17RE 876.0
ZEB1 816.0
PSME3 614.0
HSP90AA1 550.0
PSMD6 518.0
IRAK3 459.0
UBE2N 373.0
CASP8 299.0
PSMD14 114.0
IL1R1 -13.0
IL22RA2 -14.0
CCL5 -22.0
MAP3K7 -53.0
RALA -237.0
TBK1 -310.0
AKT1 -370.0
TNIP2 -371.0
RPS27A -409.0
NFKBIB -471.0
IL24 -516.0
NFKB2 -572.0
CAPZA1 -682.0
OSMR -691.0
PTPN2 -735.0
IL20RB -740.0
PTPN4 -845.0
MMP9 -850.0
COL1A2 -946.0
PPP2R5D -1030.0
RAP1B -1064.0
VAV1 -1113.0
UBE2V1 -1122.0
ANXA1 -1162.0
PSMD5 -1267.0
PSMB4 -1390.0
TIFA -1456.0
NLRX1 -1457.0
CSF3R -1521.0
MAPK10 -1570.0
NFKB1 -1676.0
VEGFA -1763.0
MAPK1 -1793.0
PRTN3 -1818.0
GSDMD -1979.0
STX4 -2002.0
IRS1 -2009.0
FGF2 -2057.0
STAT3 -2059.0
SOCS5 -2074.0
SOCS2 -2139.0
IL1RL2 -2186.0
IL5 -2227.0
CSF1 -2251.0
PIK3R3 -2257.0
IL9 -2303.0
MAPK14 -2356.0
SMARCA4 -2517.0
IL22 -2522.0
PTPN13 -2609.0
RPS6KA2 -2626.0
CASP3 -2726.0
CISH -2805.0
CRLF1 -2858.0
RPLP0 -2913.0
RPS6KA5 -2918.0
IL6R -2983.0
ATF1 -3010.0
PSMD7 -3011.0
BCL6 -3062.0
TGFB1 -3077.0
ALOX5 -3106.0
MTAP -3147.0
TP53 -3175.0
PSMB8 -3188.0
FN1 -3189.0
IL10RA -3227.0
NANOG -3267.0
H3C1 -3282.0
PTPRZ1 -3310.0
CUL1 -3367.0
ITGAM -3427.0
IL17RB -3436.0
CXCL2 -3476.0
MAP2K6 -3585.0
STAT5B -3603.0
HNRNPDL -3608.0
MMP2 -3616.0
PSMB9 -3719.0
HNRNPF -3731.0
IL17F -3747.0
TALDO1 -3750.0
CASP1 -3763.0
ALPK1 -3775.0
IL33 -3824.0
PSMD8 -3830.0
CRK -3851.0
STAT1 -3915.0
FYN -3958.0
IL17RA -4051.0
LAMA5 -4176.0
IL36RN -4177.0
JAK2 -4375.0
CNTF -4406.0
CHUK -4542.0
FPR1 -4659.0
PSMC3 -4708.0
PPP2R1B -4709.0
PIK3CB -4734.0
IFNG -4820.0
MAP2K4 -4901.0
HSPA9 -4946.0
H3C4 -4999.0
STAT5A -5020.0
FOXO1 -5042.0
MMP3 -5045.0
IRS2 -5058.0
OPRM1 -5288.0
TOLLIP -5296.0
SOD1 -5433.0
TSLP -5482.0
TAB2 -5546.0
VAMP2 -5591.0
CCL3 -5596.0
SNAP25 -5603.0
PSMA5 -5619.0
JUNB -5643.0
PTPN14 -5648.0
H3C2 -5710.0
MCL1 -5721.0
TXLNA -5756.0
LIFR -5757.0
CDC42 -5795.0
PPP2CB -5808.0
RPS6KA1 -5825.0
PRKACA -5856.0
SOS1 -5894.0
PSME4 -6007.0
PSMA2 -6134.0
OSM -6190.0
S1PR1 -6485.0
VRK3 -6529.0
PSMC2 -6591.0
CNTFR -6852.0
BATF -6853.0
MAP2K7 -6939.0
NLRC5 -6983.0
MAPKAPK3 -6984.0
APP -7137.0
LGALS9 -7201.0
PSMF1 -7266.0
PITPNA -7442.0
OPRD1 -7452.0
TYK2 -7461.0
MMP1 -7488.0
MAPK3 -7507.0
PSMD9 -7539.0
CXCL1 -7661.0
IKBKB -7739.0
INPPL1 -7799.0
IL31RA -7870.0
PSMB2 -7879.0
SIGIRR -7912.0
VCAM1 -7929.0
IL17A -8153.0
IL21 -8193.0
PTPN7 -8199.0
IRAK4 -8264.0
PSMD2 -8354.0
VIM -8420.0
NOD1 -8469.0
H3C7 -8506.5
H3C10 -8687.0
IFNL2 -8719.0
ITGB1 -8750.0
RELA -8902.0
PAK2 -8910.0
NOD2 -8985.0
F13A1 -9091.0
IL36A -9153.0
CCL11 -9157.0
MAPK9 -9162.0
CD4 -9176.0
TRAF2 -9178.0
STAT2 -9286.0
GSTA2 -9375.0
PIM1 -9550.0
IL13 -9583.0
H3C6 -9584.0
JAK3 -9597.0
CXCL10 -9659.0
CSF2RB -9682.0
AGER -9754.0
PSMB11 -9770.0
PSMB6 -9876.0
ALOX15 -10103.0
PSME1 -10185.0
LIF -10190.0
IL22RA1 -10284.0
GATA3 -10345.0
EBI3 -10361.0
SOCS3 -10374.0
BIRC5 -10419.0
IL2 -10442.0
H3C12 -10777.0
IFNL1 -10919.0
IL31 -11051.0
IL3 -11083.0


REACTOME_INFLUENZA_INFECTION

REACTOME_INFLUENZA_INFECTION
228
set REACTOME_INFLUENZA_INFECTION
setSize 149
pANOVA 0.000619
s.dist 0.162
p.adjustANOVA 0.0984



Top enriched genes

Top 20 genes
GeneID Gene Rank
NUP43 9955.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
PARP1 9435.0
RPS3 9408.0
RAE1 9369.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
NUP107 8583.0
RPL13A 8475.5

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
NUP43 9955.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
PARP1 9435.0
RPS3 9408.0
RAE1 9369.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
NUP107 8583.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
NUP54 7764.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
NUP35 7449.0
RPL22 7445.0
RPLP2 7407.0
SEH1L 7308.0
CALR 7250.0
RPS3A 7064.0
RPL5 7045.0
POLR2D 6812.0
TPR 6756.0
KPNA5 6728.0
RPL32 6495.0
RANBP2 6098.0
RPL37 6049.0
AAAS 5874.0
RAN 5724.0
POLR2E 5508.0
NUP58 5258.0
NUP210 5237.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
POLR2I 4560.0
NUP133 4093.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPL14 2956.0
RPL38 2950.0
POM121C 2812.0
NUP160 2706.0
XPO1 2379.0
RPS21 2267.0
HSPA1A 2018.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
CANX 1597.0
RPL11 1544.0
KPNA2 1445.0
RPL36 1314.0
POLR2F 1076.0
POLR2K 936.0
NUP50 736.0
POM121 659.0
HSP90AA1 550.0
RPL26 455.0
FAU 437.0
RPL28 128.0
NUP88 32.0
KPNA3 -158.0
POLR2L -338.0
RPS16 -365.0
RPS27A -409.0
CLTC -436.0
RPL37A -651.0
GTF2F2 -676.0
NUP85 -1018.0
RPL41 -1150.0
POLR2C -1312.0
KPNA7 -1385.0
KPNA1 -1441.0
RPL17 -1554.0
CLTA -1565.0
NUP188 -1603.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
POLR2B -1946.0
RPS11 -2454.0
EIF2AK2 -2548.0
RPL26L1 -2590.0
RPS9 -2591.0
POLR2H -2828.0
RPLP0 -2913.0
TGFB1 -3077.0
GTF2F1 -3086.0
RPS27L -3101.0
POLR2G -3408.0
NUP62 -3528.0
NDC1 -3639.0
GRSF1 -3707.0
RPL19 -3774.0
NUP93 -3881.0
RPS23 -3882.0
PABPN1 -4270.0
NUP214 -4467.0
KPNA4 -5038.0
NUP37 -5161.0
DNAJC3 -5385.0
NUP153 -5466.0
NUP42 -5535.0
NUP205 -5837.0
RPS27 -6223.0
SEC13 -6224.0
IPO5 -6556.0
KPNB1 -6962.0
NUP98 -7138.0
RPL30 -7243.0
RPL29 -7404.0
RPS20 -8058.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
NUP155 -8920.0
CPSF4 -8976.0
POLR2A -9547.0
RPS26 -9575.0
RPL10L -10035.0
ISG15 -10453.0
POLR2J -10455.0


REACTOME_KERATINIZATION

REACTOME_KERATINIZATION
1073
set REACTOME_KERATINIZATION
setSize 210
pANOVA 0.000659
s.dist -0.136
p.adjustANOVA 0.0984



Top enriched genes

Top 20 genes
GeneID Gene Rank
KRTAP8-1 -11156
KRTAP10-3 -11128
KRTAP5-1 -11114
KRTAP13-4 -11104
KRTAP10-2 -11046
FLG -11033
LCE1F -11002
KRTAP23-1 -10939
KRTAP13-3 -10926
SPRR2E -10864
KRTAP5-6 -10856
KRTAP3-3 -10826
LCE4A -10779
KRTAP15-1 -10655
LELP1 -10650
KRT24 -10627
LCE3E -10605
KRT75 -10566
FURIN -10501
SPINK6 -10475

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
KRTAP8-1 -11156
KRTAP10-3 -11128
KRTAP5-1 -11114
KRTAP13-4 -11104
KRTAP10-2 -11046
FLG -11033
LCE1F -11002
KRTAP23-1 -10939
KRTAP13-3 -10926
SPRR2E -10864
KRTAP5-6 -10856
KRTAP3-3 -10826
LCE4A -10779
KRTAP15-1 -10655
LELP1 -10650
KRT24 -10627
LCE3E -10605
KRT75 -10566
FURIN -10501
SPINK6 -10475
KRT39 -10423
KRT84 -10413
KRTAP19-2 -10411
KRTAP27-1 -10269
LCE5A -10198
KRT27 -10173
SPINK9 -10091
KRT9 -10078
KRT78 -10066
KRT33A -10030
KRT35 -9984
KRTAP10-8 -9956
KRT81 -9924
EVPL -9848
IVL -9794
KRTAP12-2 -9750
KRTAP10-11 -9692
KRTAP19-6 -9596
SPRR1B -9567
KRTAP1-1 -9557
CSTA -9494
KRT26 -9453
KRTAP13-2 -9422
KRTAP19-5 -9293
KLK5 -9163
KRTAP26-1 -9055
KRTAP3-1 -9021
KRTAP20-2 -9018
LCE1E -8954
TGM1 -8953
KRTAP10-12 -8925
KRTAP5-10 -8901
KRTAP2-2 -8877
KRTAP9-9 -8662
SPRR1A -8608
KRTAP2-4 -8533
LIPJ -8511
LIPN -8256
LIPK -8116
PPL -8101
KRT28 -7886
SPRR2A -7811
KLK13 -7703
SPRR2G -7643
KRTAP4-4 -7438
KRT17 -7369
PKP1 -7360
KAZN -7244
LCE1A -6986
KRTAP17-1 -6713
KRT77 -6709
KRTAP5-8 -6704
CAPN1 -6617
KRT34 -6613
KRT36 -6536
PKP3 -6489
KRTAP11-1 -6331
KRTAP9-2 -6199
KRTAP9-1 -5912
LCE3B -5890
KRTAP3-2 -5832
KRT3 -5789
KRT38 -5660
KRTAP9-6 -5592
KRT83 -5580
KRTAP1-3 -5511
CDSN -5474
KRT40 -5461
LCE6A -5382
KRTAP10-4 -5223
LCE2D -5054
KLK12 -5022
KRT12 -4898
KRT79 -4747
KRTAP12-4 -4661
CASP14 -4500
KRT71 -4457
KRTAP19-4 -4365
KRTAP19-1 -4329
KRT7 -4189
KRTAP12-3 -4146
KRT82 -4008
KRTAP5-5 -3773
KRTAP4-1 -3556
KRTAP21-3 -3544
KRTAP25-1 -3459
KRT5 -3443
LCE2A -3442
JUP -3332
ST14 -3110
PI3 -3027
KLK14 -3006
KRT86 -2929
DSC3 -2750
KRT72 -2678
KRTAP10-9 -2494
KRTAP19-3 -2405
PKP4 -2205
KRT1 -1730
KRTAP4-2 -1557
DSC2 -1481
DSG1 -1384
KRT6A -981
LCE1B -309
KRT18 -236
KRT31 -141
KRTAP6-2 37
PCSK6 154
KRTAP19-8 394
LCE1C 466
KRTAP20-1 513
KRTAP13-1 617
KRTAP2-3 783
KLK8 796
KRTAP9-3 905
LCE2B 965
KRT25 1002
KRTAP21-2 1944
SPRR3 2619
PKP2 2726
CELA2A 2818
KRT85 2824
DSG4 2997
KRT33B 3107
KRTAP24-1 3109
KRT19 3153
CAPNS1 3262
KRTAP2-1 3309
KRT6C 3324
DSP 3699
KRT10 4100
KRT23 4347
TCHH 4986
SPRR2D 5271
SPRR2F 5436
KRT4 5439
DSG3 5486
KRTAP29-1 5644
KRTAP10-10 6207
LCE2C 6361
KRTAP6-3 6545
KRT74 6650
DSG2 6719
KRTAP4-5 6729
KRTAP19-7 6875
KRT20 6889
KRTAP4-3 7141
KRTAP4-8 7232
KRT2 7620
KRTAP9-4 7736
KRT15 7893
PERP 7981
KRTAP5-4 8020
KRTAP10-5 8073
KRTAP5-3 8090
KRT32 8245
KRTAP10-7 8253
KRTAP21-1 8267
KRTAP5-9 8335
SPINK5 8336
KRT80 8541
LIPM 8604
KRT8 8621
KRTAP22-1 8640
KRTAP1-5 8658
KRT73 8701
KRTAP4-6 8741
KRT14 8838
LCE3A 8874
PRSS8 8886
RPTN 9107
KRTAP1-4 9154
KRT6B 9310
DSC1 9545
KRT76 9735
KRTAP12-1 9751
KRT37 9805
KRTAP5-11 9846
KRTAP16-1 9897
KRTAP10-6 10009
TGM5 10159
KRT13 10308
KRTAP5-2 10328
KRTAP6-1 10349
KRTAP10-1 10467
LCE3D 10480
KRTAP5-7 10602
KRTAP4-7 10607
KRT16 10715
KRTAP4-11 10745


REACTOME_SIGNALING_BY_ROBO_RECEPTORS

REACTOME_SIGNALING_BY_ROBO_RECEPTORS
605
set REACTOME_SIGNALING_BY_ROBO_RECEPTORS
setSize 206
pANOVA 0.000871
s.dist 0.135
p.adjustANOVA 0.119



Top enriched genes

Top 20 genes
GeneID Gene Rank
HOXA2 10095.0
PRKAR2A 10044.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
PRKACG 9090.0
EVL 8994.0
RPL7A 8969.0
PSMB10 8921.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HOXA2 10095.0
PRKAR2A 10044.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
PRKACG 9090.0
EVL 8994.0
RPL7A 8969.0
PSMB10 8921.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
PSMD4 8409.0
PSMC1 8362.0
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RAC1 8105.0
RPL34 8063.0
FLRT3 8034.0
EIF4G1 7992.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
PSMC6 7360.0
PSMB7 7322.0
PSMB1 7304.0
PSME2 7282.0
ELOC 7268.0
PSMB3 7246.0
PSMA1 7230.0
RPS3A 7064.0
RPL5 7045.0
PSMC5 6773.0
PSMD1 6519.0
RPL32 6495.0
SOS2 6167.0
RPL37 6049.0
LDB1 6040.0
VASP 5929.0
PFN1 5829.0
RPL3L 5231.0
RPS24 5215.0
UBB 5177.0
PSMA6 5154.0
RPL23A 5101.0
ENAH 5081.0
RPL15 5038.0
PAK6 4955.0
RPL8 4864.0
PSMA3 4777.0
RPL6 4762.0
GPC1 4696.0
RPS10 4677.0
RPS15A 4661.0
USP33 4521.0
PSMD13 4481.0
CXCR4 4383.0
PSMD11 4322.0
PSMA4 4297.0
NTN1 4005.0
RPL21 3866.0
RPLP1 3770.0
PSMC4 3690.0
RPL22L1 3661.0
CAP1 3528.0
RPL31 3526.0
RPS28 3491.0
PSMA7 3408.0
NCBP2 3349.0
RPS14 3317.0
PSMA8 3274.0
GSPT1 3260.0
PRKACB 3156.0
RPL14 2956.0
RPL38 2950.0
NRP1 2491.0
RBM8A 2326.0
RPS21 2267.0
PSMB5 2174.0
PABPC1 2008.0
RPL9 1911.0
UBC 1879.0
RPL18 1830.0
RBX1 1772.0
RPL7 1760.0
ABL2 1575.0
MYO9B 1546.0
RPL11 1544.0
SEM1 1440.0
SLIT2 1327.0
RPL36 1314.0
PSMD3 1303.0
NELL2 946.0
CXCL12 927.0
PRKCA 759.0
UPF3A 752.0
ARHGAP39 735.0
PSME3 614.0
PSMD6 518.0
RPL26 455.0
FAU 437.0
CLASP2 362.0
SRGAP3 237.0
RPL28 128.0
PSMD14 114.0
NCK2 3.0
SLIT1 -32.0
UPF2 -293.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
ROBO1 -717.0
AKAP5 -834.0
SRGAP1 -1059.0
LHX9 -1132.0
RPL41 -1150.0
PSMD5 -1267.0
PSMB4 -1390.0
RPL17 -1554.0
PAK4 -1568.0
RPS13 -1714.0
ISL1 -1737.0
RPL18A -1756.0
MSI1 -1808.0
RPL10A -1862.0
CASC3 -2082.0
LHX4 -2259.0
ETF1 -2383.0
RPS11 -2454.0
DCC -2460.0
PPP3CB -2485.0
RHOA -2508.0
RPL26L1 -2590.0
RPS9 -2591.0
SRC -2605.0
SLIT3 -2690.0
RPLP0 -2913.0
PSMD7 -3011.0
RPS27L -3101.0
PAK5 -3141.0
PSMB8 -3188.0
CAP2 -3222.0
CLASP1 -3290.0
RNPS1 -3387.0
PSMB9 -3719.0
RPL19 -3774.0
PSMD8 -3830.0
RPS23 -3882.0
PFN2 -4208.0
CUL2 -4238.0
ROBO2 -4298.0
NCBP1 -4344.0
PAK1 -4397.0
ABL1 -4417.0
PSMC3 -4708.0
NCK1 -4796.0
SRGAP2 -4972.0
MAGOH -5117.0
PSMA5 -5619.0
CDC42 -5795.0
PRKACA -5856.0
SOS1 -5894.0
PSME4 -6007.0
PSMA2 -6134.0
RPS27 -6223.0
ROBO3 -6444.0
DAG1 -6515.0
PSMC2 -6591.0
LHX2 -6619.0
RPL30 -7243.0
PSMF1 -7266.0
EIF4A3 -7272.0
RPL29 -7404.0
MAGOHB -7473.0
PSMD9 -7539.0
PSMB2 -7879.0
RPS20 -8058.0
RPS29 -8230.0
PSMD2 -8354.0
RPL27 -8392.0
ELOB -8474.0
RPL35 -8625.0
PAK2 -8910.0
LHX3 -9465.0
RPS26 -9575.0
PSMB11 -9770.0
PSMB6 -9876.0
RPL10L -10035.0
PSME1 -10185.0
ZSWIM8 -10314.0


REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS

REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
1364
set REACTOME_REGULATION_OF_EXPRESSION_OF_SLITS_AND_ROBOS
setSize 161
pANOVA 0.000957
s.dist 0.151
p.adjustANOVA 0.121



Top enriched genes

Top 20 genes
GeneID Gene Rank
HOXA2 10095.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
PSMB10 8921.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
PSMD4 8409.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HOXA2 10095.0
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
PSMB10 8921.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
PSMD4 8409.0
PSMC1 8362.0
RPL35A 8332.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
EIF4G1 7992.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
RPL22 7445.0
RPLP2 7407.0
PSMC6 7360.0
PSMB7 7322.0
PSMB1 7304.0
PSME2 7282.0
ELOC 7268.0
PSMB3 7246.0
PSMA1 7230.0
RPS3A 7064.0
RPL5 7045.0
PSMC5 6773.0
PSMD1 6519.0
RPL32 6495.0
RPL37 6049.0
LDB1 6040.0
RPL3L 5231.0
RPS24 5215.0
UBB 5177.0
PSMA6 5154.0
RPL23A 5101.0
RPL15 5038.0
RPL8 4864.0
PSMA3 4777.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
USP33 4521.0
PSMD13 4481.0
PSMD11 4322.0
PSMA4 4297.0
RPL21 3866.0
RPLP1 3770.0
PSMC4 3690.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
PSMA7 3408.0
NCBP2 3349.0
RPS14 3317.0
PSMA8 3274.0
GSPT1 3260.0
RPL14 2956.0
RPL38 2950.0
RBM8A 2326.0
RPS21 2267.0
PSMB5 2174.0
PABPC1 2008.0
RPL9 1911.0
UBC 1879.0
RPL18 1830.0
RBX1 1772.0
RPL7 1760.0
RPL11 1544.0
SEM1 1440.0
SLIT2 1327.0
RPL36 1314.0
PSMD3 1303.0
UPF3A 752.0
PSME3 614.0
PSMD6 518.0
RPL26 455.0
FAU 437.0
RPL28 128.0
PSMD14 114.0
SLIT1 -32.0
UPF2 -293.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
ROBO1 -717.0
LHX9 -1132.0
RPL41 -1150.0
PSMD5 -1267.0
PSMB4 -1390.0
RPL17 -1554.0
RPS13 -1714.0
ISL1 -1737.0
RPL18A -1756.0
MSI1 -1808.0
RPL10A -1862.0
CASC3 -2082.0
LHX4 -2259.0
ETF1 -2383.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
RPLP0 -2913.0
PSMD7 -3011.0
RPS27L -3101.0
PSMB8 -3188.0
RNPS1 -3387.0
PSMB9 -3719.0
RPL19 -3774.0
PSMD8 -3830.0
RPS23 -3882.0
CUL2 -4238.0
ROBO2 -4298.0
NCBP1 -4344.0
PSMC3 -4708.0
MAGOH -5117.0
PSMA5 -5619.0
PSME4 -6007.0
PSMA2 -6134.0
RPS27 -6223.0
ROBO3 -6444.0
DAG1 -6515.0
PSMC2 -6591.0
LHX2 -6619.0
RPL30 -7243.0
PSMF1 -7266.0
EIF4A3 -7272.0
RPL29 -7404.0
MAGOHB -7473.0
PSMD9 -7539.0
PSMB2 -7879.0
RPS20 -8058.0
RPS29 -8230.0
PSMD2 -8354.0
RPL27 -8392.0
ELOB -8474.0
RPL35 -8625.0
LHX3 -9465.0
RPS26 -9575.0
PSMB11 -9770.0
PSMB6 -9876.0
RPL10L -10035.0
PSME1 -10185.0
ZSWIM8 -10314.0


REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER

REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER
478
set REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER
setSize 77
pANOVA 0.00104
s.dist 0.216
p.adjustANOVA 0.121



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105
FGFR3 7187
FGF17 7101

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105
FGFR3 7187
FGF17 7101
PIK3R2 6512
ERBB3 5779
TRAT1 5711
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF7 5358
FGF18 5144
KLB 4842
PIK3AP1 4602
FGF6 4287
PDGFRA 4105
FGF10 4019
FGF3 3835
KL 3743
FRS2 3246
MET 3117
FGFR1 2972
PIK3R1 2800
GAB2 2556
ESR1 2393
RHOG 2306
FGF1 1692
FGF23 1055
FGFR2 929
ESR2 800
KIT 446
FGF8 199
NRG3 -470
ERBB4 -921
VAV1 -1113
GAB1 -1551
NRG1 -1678
NRG4 -1796
IRS1 -2009
FGF2 -2057
PIK3R3 -2257
STRN -2298
SRC -2605
FGF9 -2778
EGF -3230
NRG2 -3275
FYN -3958
PIK3CB -4734
FLT3 -4780
TGFA -4899
IRS2 -5058
FGF19 -5544
EREG -6751
KITLG -6856
EGFR -7457
PDGFA -7896
FGFR4 -8535
EPGN -9669
FGF22 -10022
ICOS -10796


REACTOME_FCGR_ACTIVATION

REACTOME_FCGR_ACTIVATION
400
set REACTOME_FCGR_ACTIVATION
setSize 11
pANOVA 0.0012
s.dist 0.564
p.adjustANOVA 0.129



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3G 10100
CD247 10029
FGR 9481
FCGR3A 9287
LYN 8472
SYK 7703
FCGR2A 7177
HCK 5351
YES1 4638
SRC -2605
FYN -3958

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3G 10100
CD247 10029
FGR 9481
FCGR3A 9287
LYN 8472
SYK 7703
FCGR2A 7177
HCK 5351
YES1 4638
SRC -2605
FYN -3958


REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION
1053
set REACTOME_NEUTROPHIL_DEGRANULATION
setSize 460
pANOVA 0.00127
s.dist 0.0877
p.adjustANOVA 0.129



Top enriched genes

Top 20 genes
GeneID Gene Rank
RNASE2 10763
CD33 10758
CEACAM1 10552
S100A8 10437
GPR84 10366
TBC1D10C 10296
P2RX1 10194
S100A12 10170
S100A9 10137
CR1 10120
CXCR1 10108
CALML5 10010
TMBIM1 9891
MNDA 9737
CD53 9629
CD68 9604
CTSG 9599
SERPINB10 9572
DSC1 9545
CTSC 9527

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RNASE2 10763
CD33 10758
CEACAM1 10552
S100A8 10437
GPR84 10366
TBC1D10C 10296
P2RX1 10194
S100A12 10170
S100A9 10137
CR1 10120
CXCR1 10108
CALML5 10010
TMBIM1 9891
MNDA 9737
CD53 9629
CD68 9604
CTSG 9599
SERPINB10 9572
DSC1 9545
CTSC 9527
MCEMP1 9526
SLC11A1 9516
CPNE3 9485
FGR 9481
GLIPR1 9397
TYROBP 9384
PSMD12 9352
ARHGAP9 9244
PYCARD 9188
SERPINB12 8975
S100P 8963
CEACAM6 8954
PTPRJ 8938
RAB37 8885
ARHGAP45 8812
CDK13 8810
TOM1 8730
PGLYRP1 8712
VAPA 8680
SURF4 8665
CD47 8650
AOC1 8649
NIT2 8598
GRN 8589
CNN2 8486
SLC2A3 8386
MME 8343
FCER1G 8316
S100A11 8227
LAIR1 8207
CREG1 8156
PTGES2 8113
RAC1 8105
CD93 8096
RAB7A 8086
EEF2 8075
VAT1 8025
PTAFR 8009
DOK3 7990
CHI3L1 7972
ARPC5 7928
LILRB2 7854
HSPA8 7841
FABP5 7828
GSN 7785
SIRPA 7751
ATP6V1D 7722
FTL 7715
DEFA4 7694
TICAM2 7674
RAB14 7641
ITGB2 7637
ANXA2 7581
PRSS3 7567
BIN2 7514
HSP90AB1 7509
TNFRSF1B 7459
ATP6V0C 7419
C1orf35 7326
PSMB7 7322
PSMB1 7304
TUBB4B 7295
RHOF 7262
FCGR2A 7177
PPBP 7112
HEBP2 7091
SRP14 7077
TLR2 6985
CCT8 6904
FRK 6880
PADI2 6828
PTPRC 6767
SERPINB3 6755
FCN1 6720
PSAP 6654
ARG1 6592
RAB3D 6563
PRG3 6547
PSMD1 6519
ORMDL3 6501
GSTP1 6406
OLR1 6386
TMEM63A 6373
ANO6 6332
TMC6 6271
LPCAT1 6248
NPC2 6219
IDH1 6138
ADGRE3 6094
PA2G4 6090
LRG1 6010
VAMP8 5975
DYNC1LI1 5941
PRDX6 5901
HMGB1 5850
SNAP23 5828
HEXB 5776
ACAA1 5733
RAB44 5722
CEP290 5672
QPCT 5670
AZU1 5579
HVCN1 5561
MMP8 5541
FGL2 5497
FTH1 5388
CAMP 5374
HMOX2 5372
CMTM6 5336
TTR 5211
GLB1 5192
CDA 5176
PTPRB 5089
CYSTM1 5051
RAP1A 5026
ARSA 5015
NDUFC2 4975
SLCO4C1 4940
CLEC4C 4865
SERPINB6 4858
XRCC5 4743
CD300A 4684
RAP2B 4518
SDCBP 4511
BST1 4503
TSPAN14 4498
PSMD13 4481
CD55 4458
CD44 4389
CLEC5A 4373
HPSE 4365
CAB39 4362
COTL1 4353
PSMD11 4322
ITGAX 4294
PRCP 4284
PLD1 4239
SLC44A2 4228
PPIA 4220
ALDOA 4202
DIAPH1 4167
RAB24 4164
ACP3 4133
KCNAB2 4128
GGH 4112
GM2A 4108
CAT 4096
LRRC7 4080
CPPED1 3983
DNAJC5 3968
IMPDH2 3917
PTPN6 3857
NAPRT 3740
DSP 3699
DYNLL1 3589
PLAU 3588
CAP1 3528
NCKAP1L 3509
MAN2B1 3452
ADGRG3 3366
YPEL5 3326
B4GALT1 3307
DEGS1 3306
SIRPB1 3261
SVIP 3256
OLFM4 3210
SYNGR1 3044
AGL 3013
PGM1 3001
MPO 2949
FAF2 2839
XRCC6 2838
PYGL 2791
APAF1 2773
LAMTOR3 2763
APEH 2723
PRKCD 2716
CD36 2611
TXNDC5 2561
LAMTOR2 2473
PDXK 2401
SERPINB1 2399
ATP11B 2388
CD177 2337
LILRA3 2327
MANBA 2307
RHOG 2306
FCAR 2268
C5AR1 2240
PGAM1 2212
ENPP4 2192
ADGRE5 2172
ATP6V0A1 2169
AMPD3 2150
MIF 2142
GDI2 2103
ARL8A 2065
HSPA1A 2018
VCL 1995
CTSZ 1990
LCN2 1969
ALDH3B1 1960
PGM2 1918
HSPA1B 1849
PSEN1 1609
EEF1A1 1448
MMP25 1379
ATAD3B 1356
ADAM10 1321
ACLY 1307
PSMD3 1303
IRAG2 1197
GHDC 1172
PLAUR 1114
DOCK2 1089
TUBB 1020
RAB5C 912
AP1M1 852
CSTB 802
TMEM179B 732
DSN1 705
SNAP29 599
FCGR3B 585
HSP90AA1 550
PSMD6 518
PKM 414
ATP8A1 327
DYNLT1 282
CLEC12A 278
IST1 254
CFD 245
MGST1 230
PSMD14 114
ROCK1 -29
ITGAV -45
TCIRG1 -72
ANPEP -81
CEACAM8 -123
GOLGA7 -137
NFAM1 -150
DBNL -188
RAB6A -243
NHLRC3 -303
SLC2A5 -336
HK3 -514
DERA -517
HGSNAT -527
CLEC4D -703
HRNR -841
MMP9 -850
RAB3A -873
LTA4H -914
GALNS -974
IQGAP2 -984
ACTR1B -1026
CTSH -1039
RAP1B -1064
RAB10 -1133
QSOX1 -1215
CPNE1 -1379
DSG1 -1384
ORM1 -1443
PDAP1 -1465
TRAPPC1 -1513
FOLR3 -1625
NFKB1 -1676
EPX -1692
GNS -1726
KRT1 -1730
CYBA -1747
MAPK1 -1793
PRTN3 -1818
PNP -1869
GAA -1881
ALDOC -1884
ATG7 -1939
GSDMD -1979
PLAC8 -2008
CTSB -2042
COPB1 -2165
LTF -2195
CXCR2 -2244
TIMP2 -2273
RAB31 -2301
ASAH1 -2304
FUCA2 -2329
MAPK14 -2356
DNAJC13 -2371
VPS35L -2481
RHOA -2508
PTX3 -2515
NFASC -2521
TNFAIP6 -2621
CHRNB4 -2657
ACTR10 -2775
PIGR -2787
GYG1 -2998
PSMD7 -3011
CTSA -3047
OSTF1 -3061
ALOX5 -3106
CD14 -3134
ILF2 -3218
GCA -3219
CD59 -3249
ACTR2 -3289
IMPDH1 -3296
GUSB -3318
JUP -3332
SCAMP1 -3365
ITGAM -3427
IGF2R -3470
TARM1 -3547
KCMF1 -3591
LGALS3 -3691
AP2A2 -3694
ARMC8 -3696
SLC15A4 -3945
CSNK2B -3971
RNASET2 -4028
SLC27A2 -4094
ERP44 -4130
UNC13D -4147
BRI3 -4194
C6orf120 -4232
CYB5R3 -4362
RETN -4384
TCN1 -4446
BPI -4490
ITGAL -4551
COMMD9 -4636
FPR1 -4659
B2M -4664
SIGLEC14 -4680
PSMC3 -4708
UBR4 -4733
DPP7 -4837
CTSD -4847
NBEAL2 -4856
ARSB -5046
IQGAP1 -5081
STK10 -5224
TOLLIP -5296
STBD1 -5363
DNAJC3 -5385
CTSS -5598
SNAP25 -5603
PSMA5 -5619
VNN1 -5645
CCT2 -5727
MVP -5758
PYGB -5826
S100A7 -5872
AGPAT2 -5889
RAB5B -6001
ALAD -6086
HSPA6 -6123
PSMA2 -6134
HLA-A -6170
PPIE -6192
COMMD3 -6243
TRPM2 -6318
TMEM30A -6436
NEU1 -6521
SERPINA1 -6524
CRISPLD2 -6531
ELANE -6549
PSMC2 -6591
AHSG -6606
HLA-C -6610
CAPN1 -6617
SELL -6694
MGAM -6816
SPTAN1 -6849
ADAM8 -6950
ATP11A -6955
KPNB1 -6962
CAND1 -7006
CKAP4 -7014
CD58 -7024
C3AR1 -7099
PLEKHO2 -7224
SLPI -7240
GMFG -7241
CST3 -7267
RAB4B -7291
PKP1 -7360
OSCAR -7397
NME2 -7402
ABCA13 -7536
PFKL -7553
ATP8B4 -7599
PTPRN2 -7649
CXCL1 -7661
LAMTOR1 -7679
CD63 -7723
FPR2 -7757
RAB18 -7772
FUCA1 -7783
NRAS -7941
APRT -7980
PAFAH1B2 -8008
STOM -8047
CHIT1 -8125
FLG2 -8130
STK11IP -8135
PRG2 -8198
PSMD2 -8354
AGA -8416
ADA2 -8426
HLA-B -8565
MLEC -8571
DGAT1 -8686
C3 -8692
SIGLEC9 -8751
CYFIP1 -8773
GPI -8888
CRACR2A -8959
RAB27A -8969
CANT1 -9057
HP -9503
LYZ -9635
MS4A3 -9641
A1BG -9656
CRISP3 -9829
SERPINA3 -9912
HBB -9929
PECAM1 -9989
LILRB3 -10059
CEACAM3 -10104
LAMP1 -10194
DYNC1H1 -10265
NCSTN -10362
DDOST -10369
BST2 -10372
VCP -10379
ORM2 -10450
RNASE3 -10870
STING1 -10916
SIGLEC5 -11089


REACTOME_CELLULAR_RESPONSE_TO_STARVATION

REACTOME_CELLULAR_RESPONSE_TO_STARVATION
1582
set REACTOME_CELLULAR_RESPONSE_TO_STARVATION
setSize 147
pANOVA 0.00137
s.dist 0.153
p.adjustANOVA 0.129



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
ATP6V1G1 9260.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
CEBPG 8919.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
ATP6V1G1 9260.0
RPS7 9253.0
EIF2S2 8976.0
RPL7A 8969.0
CEBPG 8919.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RPL35A 8332.0
RPSA 8200.0
EIF2S1 8154.0
RPS15 8112.0
RPL34 8063.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
ATP6V1D 7722.0
ATF4 7691.0
RPL27A 7634.0
ATP6V1G2 7528.0
RPL22 7445.0
ATP6V0C 7419.0
RPLP2 7407.0
SEH1L 7308.0
ATP6V1E2 7109.0
RPS3A 7064.0
RPL5 7045.0
RRAGD 6794.0
RPL32 6495.0
FNIP2 6324.0
DDIT3 6149.0
RPL37 6049.0
ATP6V1A 6005.0
ATF2 5785.0
RPL3L 5231.0
RPS24 5215.0
RPL23A 5101.0
RPL15 5038.0
ATP6V0E2 4914.0
RPL8 4864.0
RPL6 4762.0
IMPACT 4757.0
RPS10 4677.0
RPS15A 4661.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
ATP6V0D2 3609.0
SESN2 3568.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPL14 2956.0
RPL38 2950.0
LAMTOR3 2763.0
LAMTOR2 2473.0
ASNS 2429.0
SESN1 2361.0
RPS21 2267.0
FNIP1 2196.0
ATP6V1B1 2044.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
RRAGC 1719.0
RPL11 1544.0
KICS2 1493.0
ATP6V1G3 1374.0
RPL36 1314.0
ATP6V1B2 576.0
DEPDC5 575.0
RPL26 455.0
FAU 437.0
CASTOR1 158.0
RPL28 128.0
NPRL2 28.0
TCIRG1 -72.0
RPS16 -365.0
RPS27A -409.0
ATP6V1F -535.0
RPL37A -651.0
ATP6V0B -677.0
RPTOR -890.0
BMT2 -1129.0
RPL41 -1150.0
CEBPB -1216.0
RPL17 -1554.0
RPS13 -1714.0
RPL18A -1756.0
RPL10A -1862.0
ATF3 -2172.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
MIOS -2610.0
ATP6V0E1 -2648.0
LAMTOR5 -2866.0
RPLP0 -2913.0
RPS27L -3101.0
RHEB -3154.0
KPTN -3220.0
RPL19 -3774.0
RPS23 -3882.0
ATP6V1C1 -3891.0
EIF2AK4 -4066.0
SLC38A9 -4430.0
RRAGA -4743.0
MLST8 -5409.0
ATP6V1C2 -5453.0
ITFG2 -5678.0
ATP6V1E1 -6111.0
RPS27 -6223.0
SEC13 -6224.0
ATP6V1H -6730.0
MTOR -7026.0
RPL30 -7243.0
RPL29 -7404.0
LAMTOR4 -7556.0
LAMTOR1 -7679.0
WDR24 -7774.0
RPS20 -8058.0
SZT2 -8223.0
RPS29 -8230.0
RPL27 -8392.0
RPL35 -8625.0
WDR59 -8752.0
FLCN -8938.0
SH3BP4 -9205.0
TRIB3 -9353.0
RPS26 -9575.0
NPRL3 -9602.0
ATP6V0D1 -9812.0
GCN1 -9946.0
RPL10L -10035.0


REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
369
set REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL
setSize 122
pANOVA 0.00141
s.dist 0.167
p.adjustANOVA 0.129



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD33 10758
LILRA2 10668
CD3D 10650
LILRA1 10514
CD300LF 10446
CD22 10392
LILRB4 10368
CD19 10365
CD300C 10362
CD8B 10263
CD1C 10260
LILRA4 10102
CD3G 10100
CD247 10029
CLEC2D 10013
CD40 9787
CD3E 9720
SIGLEC8 9661
ULBP3 9616
SLAMF6 9487

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD33 10758
LILRA2 10668
CD3D 10650
LILRA1 10514
CD300LF 10446
CD22 10392
LILRB4 10368
CD19 10365
CD300C 10362
CD8B 10263
CD1C 10260
LILRA4 10102
CD3G 10100
CD247 10029
CLEC2D 10013
CD40 9787
CD3E 9720
SIGLEC8 9661
ULBP3 9616
SLAMF6 9487
TYROBP 9384
PILRB 9365
FCGR3A 9287
SIGLEC7 9224
HCST 9189
PILRA 9128
TREML2 9085
ICAM4 9000
COL17A1 8905
CD300LB 8750
ICAM5 8280
LAIR1 8207
LILRB2 7854
CD34 7817
SLAMF7 7677
ITGB2 7637
CD160 7498
CD8A 7479
CD81 7440
CD1B 7368
CRTAM 7300
NCR3 7271
HLA-E 6979
KLRG1 6924
CD200 6786
CD300LG 6653
JAML 6602
KIR3DL1 6508
HLA-G 6086
SIGLEC6 5714
ICAM3 5628
ITGB7 5218
TREML4 5174
CD1D 5088
CD226 4900
MADCAM1 4799
CD300A 4684
KLRK1 4639
CXADR 3691
CD200R1 3000
LILRB1 2754
CD96 2646
CD300LD 2622
TREML1 2498
LILRA3 2327
SFTPD 2282
ICAM1 2270
TREM2 1968
ITGA4 1423
KLRC1 829
CD300E 813
NCR3LG1 571
PIANP 528
COL1A1 355
CLEC4G 354
MICB -281
COL2A1 -339
COL1A2 -946
KIR3DL2 -966
SIGLEC1 -1604
KLRB1 -2108
NPDC1 -2254
SH2D1B -2771
NECTIN2 -3478
KIR2DL4 -4268
ITGAL -4551
B2M -4664
COL3A1 -4725
ICAM2 -5428
MICA -5752
HLA-A -6170
HLA-C -6610
SELL -6694
COLEC12 -6732
SIGLEC10 -7120
OSCAR -7397
LAIR2 -7467
SIGLEC11 -7669
LILRA5 -7744
PVR -7809
RAET1E -7865
VCAM1 -7929
KLRF1 -8111
TREM1 -8122
CDH1 -8148
CD1A -8225
CLEC2B -8457
NCR1 -8470
HLA-B -8565
NCR2 -8614
SIGLEC12 -8617
C3 -8692
ITGB1 -8750
SIGLEC9 -8751
ULBP1 -8795
HLA-F -9657
KLRD1 -10037
LILRB3 -10059
KIR2DL1 -10598
IFITM1 -10785
LILRB5 -10940
SIGLEC5 -11089


REACTOME_CD22_MEDIATED_BCR_REGULATION

REACTOME_CD22_MEDIATED_BCR_REGULATION
1007
set REACTOME_CD22_MEDIATED_BCR_REGULATION
setSize 5
pANOVA 0.00178
s.dist 0.807
p.adjustANOVA 0.154



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD79A 10694
CD22 10392
CD79B 9802
LYN 8472
PTPN6 3857

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD79A 10694
CD22 10392
CD79B 9802
LYN 8472
PTPN6 3857


REACTOME_TRANSLATION

REACTOME_TRANSLATION
1152
set REACTOME_TRANSLATION
setSize 278
pANOVA 0.00218
s.dist 0.107
p.adjustANOVA 0.179



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
SRPRA 9193.0
EIF2S2 8976.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
HARS2 8698.0
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
MRPS18A 8382.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
RPL4 9318.0
RPS7 9253.0
SRPRA 9193.0
EIF2S2 8976.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
HARS2 8698.0
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
MRPS18A 8382.0
RPL35A 8332.0
YARS2 8312.0
PPA2 8232.0
RPSA 8200.0
EIF2S1 8154.0
RPS15 8112.0
MRPS10 8094.0
EEF1A2 8084.0
EEF2 8075.0
RPL34 8063.0
MRPL57 8054.0
NARS2 8023.0
EIF4G1 7992.0
RPS6 7877.0
SPCS1 7833.0
UBA52 7820.0
RPS19 7794.0
RPL39L 7737.0
RPL13 7732.0
EEF1B2 7682.0
MRPS16 7655.0
RPL27A 7634.0
MRPS35 7571.0
RPL22 7445.0
RPLP2 7407.0
MRPL15 7253.0
GADD45GIP1 7172.0
FARSA 7126.0
EIF4A1 7104.0
SRP14 7077.0
RPS3A 7064.0
TUFM 7049.0
RPL5 7045.0
MARS2 6913.0
MRPL40 6869.0
SEC61B 6867.0
MRPS9 6663.0
RPL32 6495.0
EIF5B 6294.0
MRPS11 6199.0
MRPS15 6092.0
RPL37 6049.0
MRPL16 5826.0
MRPL36 5813.0
TRAM1 5668.0
MRPL53 5594.0
MRPL12 5572.0
MRPS33 5554.0
PARS2 5469.0
WARS1 5450.0
MRPS30 5431.0
MRPL27 5429.0
SRP72 5421.0
AIMP1 5405.0
MRPL37 5300.0
MRPS6 5288.0
RPL3L 5231.0
RPS24 5215.0
MRPL18 5197.0
MRPL1 5163.0
RPL23A 5101.0
RPL15 5038.0
EIF4A2 4942.0
EIF3E 4934.0
RPL8 4864.0
MRPL17 4793.0
RPL6 4762.0
EEF1G 4746.0
RPS10 4677.0
RPS15A 4661.0
MRPL14 4522.0
SEC61G 4455.0
LARS1 4450.0
EARS2 4423.0
SPCS3 4372.0
EIF4H 4356.0
MRPS27 4338.0
MRPL51 4283.0
MRPL55 4247.0
TRMT112 4240.0
DARS1 4144.0
MTFMT 3947.0
SSR1 3939.0
CARS2 3881.0
RPL21 3866.0
TSFM 3809.0
MRPL39 3771.0
RPLP1 3770.0
SRP54 3696.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
MRPL34 3472.0
RPS14 3317.0
GSPT1 3260.0
MRPL21 3097.0
VARS2 3085.0
EIF3I 3026.0
MTIF2 3008.0
RPL14 2956.0
RPL38 2950.0
APEH 2723.0
SSR3 2591.0
SARS2 2572.0
EIF2B1 2554.0
CHCHD1 2542.0
RPS21 2267.0
MRPS23 2219.0
OXA1L 2160.0
NARS1 2099.0
PABPC1 2008.0
RPN2 1932.0
RPL9 1911.0
RPL18 1830.0
MRPL11 1788.0
RPL7 1760.0
MRPL46 1702.0
MRPL9 1681.0
RPL11 1544.0
EEF1A1 1448.0
MRPL35 1395.0
RPL36 1314.0
EPRS1 1271.0
MRPL24 1259.0
MRPS12 1205.0
MRPL47 1147.0
MRPL28 969.0
MRPS25 770.0
GFM1 734.0
MRPL4 590.0
EIF3J 499.0
RPL26 455.0
FAU 437.0
SRP19 246.0
PPA1 162.0
RPL28 128.0
WARS2 55.0
MRPS24 -192.0
EIF3L -197.0
MRPL2 -230.0
EIF4E -316.0
RPS16 -365.0
EIF4B -397.0
RPS27A -409.0
MTIF3 -455.0
MRPL54 -507.0
MRPL49 -611.0
RPL37A -651.0
HARS1 -759.0
EIF2B2 -769.0
EIF2B4 -1008.0
RPL41 -1150.0
MRPS17 -1153.0
SSR2 -1164.0
SEC61A1 -1197.0
EIF3A -1255.0
RARS1 -1308.0
EIF3F -1373.0
SEC11A -1488.0
RPL17 -1554.0
EIF3D -1713.0
RPS13 -1714.0
EIF3M -1717.0
RPL18A -1756.0
KARS1 -1845.0
RPL10A -1862.0
MRPS34 -1974.0
LARS2 -1998.0
MRPL44 -2010.0
MRPL48 -2150.0
ETF1 -2383.0
VARS1 -2395.0
RPS11 -2454.0
EIF3G -2455.0
MRPS31 -2476.0
RPL26L1 -2590.0
RPS9 -2591.0
MRPL50 -2679.0
MRPL32 -2721.0
MTRF1L -2821.0
ERAL1 -2835.0
RPLP0 -2913.0
MRPL10 -2917.0
MRPS26 -3045.0
YARS1 -3054.0
IARS1 -3084.0
RPS27L -3101.0
EIF2B3 -3286.0
EIF2B5 -3343.0
MRPS28 -3572.0
MRPL3 -3594.0
MRPL45 -3647.0
MRPS7 -3680.0
AARS1 -3771.0
RPL19 -3774.0
EIF3B -3790.0
RPS23 -3882.0
RPN1 -3957.0
GFM2 -3989.0
MRPL19 -3995.0
GARS1 -4180.0
MRPS18B -4202.0
FARSB -4214.0
SRP9 -4308.0
MRPL33 -4319.0
MRPL52 -4476.0
EIF3K -4513.0
RARS2 -5093.0
MRPL38 -5244.0
AARS2 -5848.0
SRPRB -5909.0
EEF1E1 -6152.0
TARS1 -6162.0
AIMP2 -6219.0
RPS27 -6223.0
SPCS2 -6351.0
EIF3H -6415.0
MRPS5 -6450.0
MRPS22 -6490.0
SRP68 -6528.0
DARS2 -6543.0
MRPS18C -6586.0
MRRF -6817.0
FARS2 -6912.0
MRPS21 -6921.0
TARS2 -6968.0
PTCD3 -7109.0
MRPL43 -7130.0
EIF5 -7150.0
RPL30 -7243.0
MRPS2 -7278.0
SEC11C -7287.0
MRPL13 -7317.0
RPL29 -7404.0
EEF1D -7511.0
MRPL23 -7705.0
CARS1 -7821.0
IARS2 -7974.0
RPS20 -8058.0
AURKAIP1 -8180.0
MRPL42 -8195.0
RPS29 -8230.0
MRPL41 -8271.0
RPL27 -8392.0
RPL35 -8625.0
MRPL30 -8690.0
MARS1 -8722.0
MRPL58 -9099.0
SEC61A2 -9358.0
DAP3 -9385.0
MRPS14 -9537.0
MRPL22 -9545.0
RPS26 -9575.0
EIF4EBP1 -9694.0
N6AMT1 -9723.0
MRPL20 -9785.0
RPL10L -10035.0
DDOST -10369.0


REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
1082
set REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize 125
pANOVA 0.00231
s.dist -0.158
p.adjustANOVA 0.181



Top enriched genes

Top 20 genes
GeneID Gene Rank
FLG -11033
LCE1F -11002
SPRR2E -10864
LCE4A -10779
LELP1 -10650
KRT24 -10627
LCE3E -10605
KRT75 -10566
FURIN -10501
SPINK6 -10475
KRT39 -10423
KRT84 -10413
LCE5A -10198
KRT27 -10173
SPINK9 -10091
KRT9 -10078
KRT78 -10066
KRT33A -10030
KRT35 -9984
KRT81 -9924

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FLG -11033
LCE1F -11002
SPRR2E -10864
LCE4A -10779
LELP1 -10650
KRT24 -10627
LCE3E -10605
KRT75 -10566
FURIN -10501
SPINK6 -10475
KRT39 -10423
KRT84 -10413
LCE5A -10198
KRT27 -10173
SPINK9 -10091
KRT9 -10078
KRT78 -10066
KRT33A -10030
KRT35 -9984
KRT81 -9924
EVPL -9848
IVL -9794
SPRR1B -9567
CSTA -9494
KRT26 -9453
KLK5 -9163
LCE1E -8954
TGM1 -8953
SPRR1A -8608
LIPJ -8511
LIPN -8256
LIPK -8116
PPL -8101
KRT28 -7886
SPRR2A -7811
KLK13 -7703
SPRR2G -7643
KRT17 -7369
PKP1 -7360
KAZN -7244
LCE1A -6986
KRT77 -6709
CAPN1 -6617
KRT34 -6613
KRT36 -6536
PKP3 -6489
LCE3B -5890
KRT3 -5789
KRT38 -5660
KRT83 -5580
CDSN -5474
KRT40 -5461
LCE6A -5382
LCE2D -5054
KLK12 -5022
KRT12 -4898
KRT79 -4747
CASP14 -4500
KRT71 -4457
KRT7 -4189
KRT82 -4008
KRT5 -3443
LCE2A -3442
JUP -3332
ST14 -3110
PI3 -3027
KLK14 -3006
KRT86 -2929
DSC3 -2750
KRT72 -2678
PKP4 -2205
KRT1 -1730
DSC2 -1481
DSG1 -1384
KRT6A -981
LCE1B -309
KRT18 -236
KRT31 -141
PCSK6 154
LCE1C 466
KLK8 796
LCE2B 965
KRT25 1002
SPRR3 2619
PKP2 2726
CELA2A 2818
KRT85 2824
DSG4 2997
KRT33B 3107
KRT19 3153
CAPNS1 3262
KRT6C 3324
DSP 3699
KRT10 4100
KRT23 4347
TCHH 4986
SPRR2D 5271
SPRR2F 5436
KRT4 5439
DSG3 5486
LCE2C 6361
KRT74 6650
DSG2 6719
KRT20 6889
KRT2 7620
KRT15 7893
PERP 7981
KRT32 8245
SPINK5 8336
KRT80 8541
LIPM 8604
KRT8 8621
KRT73 8701
KRT14 8838
LCE3A 8874
PRSS8 8886
RPTN 9107
KRT6B 9310
DSC1 9545
KRT76 9735
KRT37 9805
TGM5 10159
KRT13 10308
LCE3D 10480
KRT16 10715


REACTOME_REGULATION_OF_SIGNALING_BY_CBL

REACTOME_REGULATION_OF_SIGNALING_BY_CBL
1435
set REACTOME_REGULATION_OF_SIGNALING_BY_CBL
setSize 22
pANOVA 0.00327
s.dist 0.362
p.adjustANOVA 0.238



Top enriched genes

Top 20 genes
GeneID Gene Rank
PIK3CD 8742
GRB2 8575
LYN 8472
CBL 8272
UBA52 7820
SYK 7703
CRKL 7676
BLNK 6870
PIK3R2 6512
PIK3CA 5509
HCK 5351
UBB 5177
YES1 4638
RAPGEF1 2834
PIK3R1 2800
UBC 1879
RPS27A -409
VAV1 -1113
PIK3R3 -2257
CRK -3851

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
PIK3CD 8742
GRB2 8575
LYN 8472
CBL 8272
UBA52 7820
SYK 7703
CRKL 7676
BLNK 6870
PIK3R2 6512
PIK3CA 5509
HCK 5351
UBB 5177
YES1 4638
RAPGEF1 2834
PIK3R1 2800
UBC 1879
RPS27A -409
VAV1 -1113
PIK3R3 -2257
CRK -3851
FYN -3958
PIK3CB -4734


REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
115
set REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX
setSize 134
pANOVA 0.00334
s.dist -0.147
p.adjustANOVA 0.238



Top enriched genes

Top 20 genes
GeneID Gene Rank
FURIN -10501
KLKB1 -10449
CAPN15 -10373
NCSTN -10362
CAPN3 -10240
COL11A1 -10148
MMP12 -10000
MMP13 -9589
CTRB1 -9004
CAPNS2 -8945
ADAMTS16 -8700
COL10A1 -8699
FBN3 -8526
COL6A2 -8332
ADAM15 -8268
CTRB2 -8262
ACAN -8188
CDH1 -8148
COL5A1 -8057
ADAMTS9 -7696

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FURIN -10501
KLKB1 -10449
CAPN15 -10373
NCSTN -10362
CAPN3 -10240
COL11A1 -10148
MMP12 -10000
MMP13 -9589
CTRB1 -9004
CAPNS2 -8945
ADAMTS16 -8700
COL10A1 -8699
FBN3 -8526
COL6A2 -8332
ADAM15 -8268
CTRB2 -8262
ACAN -8188
CDH1 -8148
COL5A1 -8057
ADAMTS9 -7696
CAPN7 -7616
MMP1 -7488
ADAM8 -6950
KLK7 -6881
COL4A4 -6876
CAPN9 -6759
MMP14 -6739
CAPN1 -6617
CAPN10 -6574
ELANE -6549
MMP10 -6438
SCUBE1 -6357
CAPN14 -6300
FBN1 -6064
HTRA1 -6039
COL6A5 -5796
ADAM9 -5708
MMP7 -5705
CTSS -5598
CAPN8 -5496
CAPN11 -5355
HSPG2 -5344
COL5A3 -5212
COL4A2 -5180
MMP3 -5045
CAPN13 -5018
BSG -4889
MMP16 -4883
CTSD -4847
COL3A1 -4725
COL6A6 -4284
PLG -4195
MMP24 -4188
LAMA5 -4176
LAMC2 -4126
CMA1 -3955
COL9A1 -3740
COL6A3 -3724
COL8A1 -3708
ADAM17 -3683
MMP2 -3616
FN1 -3189
ADAMTS18 -2798
CASP3 -2726
BMP1 -2465
MMP11 -2349
TIMP2 -2273
LAMB1 -2176
COL4A1 -2060
CTSB -2042
CAPN12 -1724
COL9A3 -1442
CTSL -1259
COL6A1 -1253
COL11A2 -1185
SPP1 -1056
COL1A2 -946
MMP9 -850
TLL2 -659
COL8A2 -361
COL2A1 -339
MMP15 -335
COL9A2 -304
CAPN2 -297
LAMC1 23
FBN2 125
COL19A1 293
LAMB3 339
COL1A1 355
COL13A1 548
COL12A1 738
CAPN5 791
COL18A1 1118
TMPRSS6 1121
ADAM10 1321
MMP25 1379
COL23A1 1409
COL14A1 1550
PSEN1 1609
CAST 2220
CTSK 2233
ADAMTS4 2291
NID1 2314
COL15A1 2362
COL26A1 2412
SCUBE3 2545
TLL1 2730
COL16A1 2952
MMP17 3158
CAPNS1 3262
ADAMTS1 3268
OPTC 3393
DCN 4130
CD44 4389
COL25A1 4552
COL4A3 4784
KLK2 5184
PRSS1 5235
MMP20 5236
MMP8 5541
ADAMTS5 5603
COL5A2 5709
ADAMTS8 6076
MMP19 6186
PHYKPL 6327
ELN 6964
BCAN 7124
SPOCK3 7217
COL7A1 8327
COL17A1 8905
CTSV 9232
A2M 9280
LAMA3 9436
CTSG 9599


REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
973
set REACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS
setSize 418
pANOVA 0.00352
s.dist 0.0832
p.adjustANOVA 0.241



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
DKK4 10584
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HDAC5 10058
HBEGF 10041
CD86 9958
FZD6 9930
TGFBR1 9803
PDGFB 9767
BTC 9757
CD80 9595
SYVN1 9523
NR4A1 9496
FGF20 9459
PLCG1 9389
PSMD12 9352
PDGFRB 9216

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632
DKK4 10584
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HDAC5 10058
HBEGF 10041
CD86 9958
FZD6 9930
TGFBR1 9803
PDGFB 9767
BTC 9757
CD80 9595
SYVN1 9523
NR4A1 9496
FGF20 9459
PLCG1 9389
PSMD12 9352
PDGFRB 9216
PSMB10 8921
LMNA 8846
FZD4 8845
SPRED3 8789
PIK3CD 8742
FLT3LG 8737
BCL2L1 8672
HGF 8662
TPM3 8612
GRB2 8575
RBPJ 8543
LYN 8472
PSMD4 8409
HEY1 8403
ERBB2 8390
PSMC1 8362
CBL 8272
RAC1 8105
DUSP6 8057
APH1B 7903
RPS6 7877
KAT2A 7875
UBA52 7820
DLL1 7665
NEURL1 7658
CSK 7572
BIN2 7514
PSMC6 7360
HES1 7356
PSMB7 7322
PSMB1 7304
SPRED1 7301
PSME2 7282
PSMB3 7246
PSMA1 7230
FGFR3 7187
FGF17 7101
DLL4 7060
HEY2 7051
TCF7L2 7043
CAMK2G 7003
SKP1 6937
POLR2D 6812
ZC3HAV1 6787
PSMC5 6773
TPR 6756
ARRB2 6704
KDR 6632
HDAC11 6605
KREMEN1 6587
MYC 6530
PSMD1 6519
PIK3R2 6512
PRKAR1A 6364
SEL1L 6357
AGGF1 6314
TFG 6194
HDAC1 6190
RPS6KB2 6157
DUSP7 6119
RANBP2 6098
BIRC6 6023
ERBB3 5779
TGFBR2 5767
PPP2CA 5736
TRAT1 5711
DKK1 5694
MAML1 5665
APC 5661
DHH 5649
PIK3CA 5509
POLR2E 5508
FGF5 5471
FGF4 5452
WDR48 5451
PTPN11 5384
FGF7 5358
PPM1B 5348
HDAC7 5324
TRAK1 5220
PRR5 5200
UBB 5177
PSMA6 5154
FGF18 5144
FOXO3 5124
APBB1IP 5054
SMAD2 5036
RAP1A 5026
HDAC2 4994
BCL2A1 4957
CPSF6 4876
KLB 4842
HES5 4818
PSMA3 4777
BCL2L11 4775
TLN1 4754
FZD8 4753
HDAC3 4748
EEF1G 4746
NEURL1B 4680
YES1 4638
PIK3AP1 4602
POLR2I 4560
PSMD13 4481
PSMD11 4322
PSMA4 4297
FGF6 4287
CAMK2D 4280
MYH9 4268
NPM1 4266
SHC1 4154
FZD5 4106
PDGFRA 4105
PPP1CB 4051
FGF10 4019
AKT1S1 3978
SPRED2 3869
FGF3 3835
FGB 3817
KL 3743
TNKS 3727
PSMC4 3690
LMO7 3633
PPP2R5B 3627
CDKN1A 3616
ERBIN 3417
MYO18A 3412
PSMA7 3408
NCBP2 3349
CAMK2A 3300
PSMA8 3274
FRS2 3246
AKAP9 3209
MET 3117
ZFYVE9 3091
SQSTM1 3052
KANK1 3027
FGFR1 2972
MPRIP 2874
PIK3R1 2800
PHB1 2765
CDKN1B 2756
HEYL 2662
PPP2R1A 2659
JAG1 2647
CDK8 2641
NF1 2562
SPTBN1 2557
GAB2 2556
AP3B1 2494
NCOR1 2444
MAP2K1 2431
ESR1 2393
RHOG 2306
ACTG1 2257
ITGA2B 2256
ITGB3 2218
ETV6 2200
PSMB5 2174
BCL11A 2101
GSK3A 2051
KIAA1549 2050
VCL 1995
FRS3 1906
UBC 1879
TRIP11 1871
PTPN12 1842
RBX1 1772
CREB1 1764
CNTRL 1759
SNW1 1745
MARK3 1731
FGF1 1692
LRP6 1615
PSEN1 1609
SMAD3 1511
SEM1 1440
DUSP16 1339
ADAM10 1321
FKBP1A 1316
PSMD3 1303
JAG2 1298
CSNK1A1 1200
TNKS2 1186
FAM114A2 1108
POLR2F 1076
FGF23 1055
FBXW7 1047
BCR 1013
CCNC 991
QKI 988
ALK 939
POLR2K 936
FGFR2 929
BRAF 901
FXR1 893
MAML3 847
MAML2 840
ESR2 800
HDAC10 704
PSME3 614
FGG 601
HSP90AA1 550
IHH 527
ACTB 524
PSMD6 518
KIT 446
PPP1CC 410
RNF43 337
CASP9 286
HDAC4 241
FGF8 199
FGFR1OP2 159
PSMD14 114
MDM2 76
RAF1 29
PPP2R5E -323
POLR2L -338
AKT1 -370
ARRB1 -391
RPS27A -409
CLTC -436
NRG3 -470
SHOC2 -523
WNT3A -586
ERLIN2 -660
GTF2F2 -676
PPFIBP1 -693
DERL2 -702
PPP2R5C -775
PTEN -898
MAPKAP1 -919
ERBB4 -921
ZMYM2 -925
PPP2R5D -1030
RAP1B -1064
VAV1 -1113
CEBPB -1216
PSMD5 -1267
GSK3B -1274
HIP1 -1284
POLR2C -1312
PSMB4 -1390
YWHAB -1452
GAB1 -1551
CLCN6 -1608
MIB1 -1677
NRG1 -1678
HDAC9 -1694
CUX1 -1719
MAPK1 -1793
NRG4 -1796
PPP2R5A -1835
KIF5B -1852
EML4 -1930
ATG7 -1939
POLR2B -1946
IRS1 -2009
CTBP1 -2035
NOX4 -2050
FGF2 -2057
STAT3 -2059
KREMEN2 -2158
RRBP1 -2199
PIK3R3 -2257
STRN -2298
KDM7A -2308
BAD -2389
VWF -2453
LRRFIP1 -2503
SRC -2605
FGF9 -2778
POLR2H -2828
PSMD7 -3011
TGFB1 -3077
GTF2F1 -3086
APH1A -3160
PSMB8 -3188
FN1 -3189
ZC3HC1 -3225
EGF -3230
ESRP1 -3242
BAG4 -3254
NRG2 -3275
FOXO6 -3278
GOLGB1 -3329
CUL1 -3367
AKT3 -3379
POLR2G -3408
TRIM24 -3549
NCOR2 -3557
STAT5B -3603
ADAM17 -3683
WDCP -3686
PSMB9 -3719
MRAS -3722
CNKSR1 -3729
CALM1 -3759
AXIN1 -3805
PSMD8 -3830
KLC1 -3834
STAT1 -3915
FYN -3958
SND1 -3994
HHAT -4044
PEBP1 -4224
TENT4A -4250
NCBP1 -4344
JAK2 -4375
KSR2 -4484
CAMK2B -4518
CHUK -4542
MAP3K11 -4697
PSMC3 -4708
PPP2R1B -4709
PIK3CB -4734
FIP1L1 -4745
PAPSS1 -4768
FLT3 -4780
TGFA -4899
STAT5A -5020
FOXO1 -5042
IRS2 -5058
IQGAP1 -5081
GCC2 -5162
HRAS -5216
CTBP2 -5219
DUSP10 -5305
MLST8 -5409
TSC2 -5491
AKT2 -5525
FGF19 -5544
PSMA5 -5619
JUNB -5643
EP300 -5781
KSR1 -5786
PPP2CB -5808
SEC31A -5847
AGTRAP -5868
SOS1 -5894
OS9 -5997
PSME4 -6007
RICTOR -6117
PSMA2 -6134
CEP43 -6150
PSEN2 -6355
NOTCH1 -6398
SHH -6540
AGK -6542
PSMC2 -6591
EREG -6751
DCTN1 -6794
TBL1XR1 -6802
KITLG -6856
MTOR -7026
EIF2AK3 -7063
TPM4 -7113
PSMF1 -7266
ERLEC1 -7355
SMAD4 -7376
EGFR -7457
DKK2 -7502
MAPK3 -7507
PSMD9 -7539
FGA -7698
BRAP -7746
CREBBP -7802
CARS1 -7821
PSMB2 -7879
PDGFA -7896
PDPK1 -7938
NRAS -7941
KRAS -7949
ATIC -7968
LRP5 -7991
MIB2 -8010
DUSP8 -8143
PSENEN -8163
CDC37 -8277
PSMD2 -8354
KAT2B -8525
FGFR4 -8535
RNF213 -8652
CTNNB1 -8712
MAP2K2 -9159
FAM131B -9172
GOLGA4 -9488
POLR2A -9547
PIM1 -9550
EPGN -9669
PSMB11 -9770
PSMB6 -9876
FGF22 -10022
PSME1 -10185
NCSTN -10362
VCP -10379
POLR2J -10455
ICOS -10796


REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM
227
set REACTOME_INNATE_IMMUNE_SYSTEM
setSize 1002
pANOVA 0.00379
s.dist 0.054
p.adjustANOVA 0.243



Top enriched genes

Top 20 genes
GeneID Gene Rank
RNASE2 10763.0
CD33 10758.0
IFNA21 10747.0
TLR9 10710.0
CCL22 10699.0
DEFB114 10669.0
GRAP2 10646.0
SFTPA1 10645.0
RAC2 10632.0
CEACAM1 10552.0
RNASE6 10516.0
CCR2 10497.0
PLD4 10482.0
LCK 10443.0
S100A8 10437.0
GPR84 10366.0
CD19 10365.0
DEFB104A 10319.5
DEFB104B 10319.5
IFNA2 10310.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RNASE2 10763.0
CD33 10758.0
IFNA21 10747.0
TLR9 10710.0
CCL22 10699.0
DEFB114 10669.0
GRAP2 10646.0
SFTPA1 10645.0
RAC2 10632.0
CEACAM1 10552.0
RNASE6 10516.0
CCR2 10497.0
PLD4 10482.0
LCK 10443.0
S100A8 10437.0
GPR84 10366.0
CD19 10365.0
DEFB104A 10319.5
DEFB104B 10319.5
IFNA2 10310.0
TBC1D10C 10296.0
LY86 10294.0
CFHR2 10220.0
PGLYRP4 10200.0
P2RX1 10194.0
SAA1 10186.0
MYD88 10180.0
IFNA7 10175.0
S100A12 10170.0
IFNA8 10158.0
SIGLEC15 10151.0
S100A9 10137.0
CR1 10120.0
CXCR1 10108.0
CD3G 10100.0
TRIM4 10059.0
CD247 10029.0
CALML5 10010.0
TMBIM1 9891.0
UNC93B1 9814.0
IRAK2 9811.0
DEFA6 9788.0
MNDA 9737.0
IFNA1 9736.0
NCF2 9704.0
DCD 9633.0
CD53 9629.0
CD68 9604.0
CTSG 9599.0
SERPINB10 9572.0
DSC1 9545.0
CTSC 9527.0
MCEMP1 9526.0
SLC11A1 9516.0
HSP90B1 9493.0
CPNE3 9485.0
FGR 9481.0
C1R 9450.0
FCN2 9449.0
GLIPR1 9397.0
PLCG1 9389.0
TYROBP 9384.0
PSMD12 9352.0
CGAS 9332.0
FCGR3A 9287.0
CLEC10A 9271.0
ATP6V1G1 9260.0
ARHGAP9 9244.0
CTSV 9232.0
PYCARD 9188.0
RNF135 9114.0
PRKACG 9090.0
HTN3 9086.0
MUC1 9080.0
MUC20 8990.0
SERPINB12 8975.0
S100P 8963.0
CEACAM6 8954.0
PTPRJ 8938.0
PSMB10 8921.0
RAB37 8885.0
CD180 8867.0
ARHGAP45 8812.0
CDK13 8810.0
DUSP4 8770.0
C8G 8765.0
CD300LB 8750.0
BCL2 8749.0
TOM1 8730.0
PGLYRP1 8712.0
MASP1 8690.0
PRKCSH 8683.0
MYO1C 8681.0
VAPA 8680.0
BCL2L1 8672.0
SURF4 8665.0
CD47 8650.0
AOC1 8649.0
NIT2 8598.0
GRN 8589.0
GRB2 8575.0
CNN2 8486.0
LYN 8472.0
USP18 8447.0
PSMD4 8409.0
SLC2A3 8386.0
PSMC1 8362.0
MME 8343.0
FCER1G 8316.0
ABI1 8259.0
DUSP3 8236.0
S100A11 8227.0
LAIR1 8207.0
CREG1 8156.0
PTGES2 8113.0
RAC1 8105.0
CD93 8096.0
RAB7A 8086.0
EEF2 8075.0
DUSP6 8057.0
VAT1 8025.0
NKIRAS2 8013.0
PTAFR 8009.0
DOK3 7990.0
CHI3L1 7972.0
ARPC5 7928.0
MEF2C 7901.0
LILRB2 7854.0
HSPA8 7841.0
FABP5 7828.0
BPIFA2 7824.0
UBA52 7820.0
STAT6 7801.0
GSN 7785.0
MUC12 7752.0
SIRPA 7751.0
TXK 7745.0
ATP6V1D 7722.0
FTL 7715.0
SYK 7703.0
DEFA4 7694.0
IFNA14 7690.0
TICAM2 7674.0
RAB14 7641.0
ITGB2 7637.0
PSTPIP1 7610.0
LY96 7594.0
ANXA2 7581.0
PRSS3 7567.0
AHCYL1 7545.0
ATP6V1G2 7528.0
BIN2 7514.0
HSP90AB1 7509.0
PELI3 7480.0
TNFRSF1B 7459.0
CD81 7440.0
ATP6V0C 7419.0
DNM1 7364.0
PSMC6 7360.0
REG3G 7332.0
C1orf35 7326.0
PSMB7 7322.0
PSMB1 7304.0
TUBB4B 7295.0
PSME2 7282.0
RHOF 7262.0
PSMB3 7246.0
PSMA1 7230.0
FCGR2A 7177.0
NCKIPSD 7120.0
C8A 7119.0
PPBP 7112.0
ATP6V1E2 7109.0
HEBP2 7091.0
MAP2K3 7085.0
ART1 7084.0
SRP14 7077.0
CHGA 7058.0
MAP3K8 7028.0
RASGRP4 6994.0
TLR2 6985.0
HLA-E 6979.0
SKP1 6937.0
CCT8 6904.0
FRK 6880.0
PADI2 6828.0
C8B 6797.0
ITCH 6780.0
LCP2 6777.0
PSMC5 6773.0
PTPRC 6767.0
SERPINB3 6755.0
NOS3 6751.0
FCN1 6720.0
C5AR2 6706.0
PSAP 6654.0
MAP3K1 6627.0
SARM1 6595.0
ARG1 6592.0
TRAF6 6579.0
RAB3D 6563.0
PRG3 6547.0
PSMD1 6519.0
PIK3R2 6512.0
ORMDL3 6501.0
GSTP1 6406.0
OLR1 6386.0
TMEM63A 6373.0
SERPING1 6348.0
NFATC3 6345.0
ANO6 6332.0
IKBIP 6279.0
TMC6 6271.0
LPCAT1 6248.0
ZBP1 6221.0
NPC2 6219.0
PELI2 6217.0
CFL1 6160.0
IDH1 6138.0
DUSP7 6119.0
ADGRE3 6094.0
PA2G4 6090.0
DEFB115 6035.0
LRG1 6010.0
ATP6V1A 6005.0
VAMP8 5975.0
DYNC1LI1 5941.0
POLR1C 5940.0
PRDX6 5901.0
HMGB1 5850.0
SNAP23 5828.0
NF2 5820.0
S100A1 5800.0
ATF2 5785.0
HEXB 5776.0
PPP2CA 5736.0
ACAA1 5733.0
RAB44 5722.0
DEFB119 5681.0
CEP290 5672.0
QPCT 5670.0
POLR3G 5662.0
DNM2 5639.0
ICAM3 5628.0
AZU1 5579.0
CLU 5575.0
HVCN1 5561.0
AAMP 5559.0
MMP8 5541.0
PIK3CA 5509.0
POLR2E 5508.0
FGL2 5497.0
PELI1 5473.0
FTH1 5388.0
PTPN11 5384.0
CAMP 5374.0
HMOX2 5372.0
HCK 5351.0
CMTM6 5336.0
C6 5296.0
ITK 5227.0
TTR 5211.0
GLB1 5192.0
UBB 5177.0
CDA 5176.0
BIRC2 5170.0
BPIFB2 5159.0
PSMA6 5154.0
WIPF1 5120.0
PTPRB 5089.0
PRKCE 5066.0
CYSTM1 5051.0
RAP1A 5026.0
ARSA 5015.0
NDUFC2 4975.0
SLCO4C1 4940.0
UBA3 4937.0
RIPK3 4916.0
ATP6V0E2 4914.0
CLEC4C 4865.0
SERPINB6 4858.0
SOCS1 4802.0
MUC6 4789.0
PSMA3 4777.0
XRCC5 4743.0
PGLYRP2 4732.0
CD300A 4684.0
KLRK1 4639.0
YES1 4638.0
N4BP1 4632.0
LBP 4617.0
TRAF3 4587.0
MAPK7 4565.0
RAP2B 4518.0
PLD3 4515.0
SDCBP 4511.0
BST1 4503.0
TSPAN14 4498.0
CFI 4494.0
PSMD13 4481.0
HMOX1 4473.0
CD55 4458.0
MAPK13 4434.0
TXNIP 4432.0
CD44 4389.0
CPB2 4379.0
CLEC5A 4373.0
HPSE 4365.0
CAB39 4362.0
COTL1 4353.0
PSMD11 4322.0
PSMA4 4297.0
ITGAX 4294.0
PRCP 4284.0
MYH9 4268.0
PLD1 4239.0
SLC44A2 4228.0
PPIA 4220.0
ALDOA 4202.0
NLRC3 4192.0
NFKBIA 4178.0
DIAPH1 4167.0
RAB24 4164.0
SHC1 4154.0
CNPY3 4150.0
ACP3 4133.0
KCNAB2 4128.0
GGH 4112.0
GM2A 4108.0
CAT 4096.0
MAPKAPK2 4095.0
LRRC7 4080.0
DEFB132 4073.0
WASF1 4067.0
TXN 4057.0
CPPED1 3983.0
DNAJC5 3968.0
TAX1BP1 3923.0
IMPDH2 3917.0
S100B 3910.0
PTPN6 3857.0
DHX58 3849.0
RIPK2 3847.0
FGB 3817.0
FOS 3811.0
JUN 3797.0
MAPK11 3753.0
NAPRT 3740.0
MAPK12 3715.0
DSP 3699.0
PSMC4 3690.0
TRIM32 3678.0
MUC15 3635.0
ATP6V0D2 3609.0
DYNLL1 3589.0
PLAU 3588.0
CR2 3559.0
CAP1 3528.0
NCKAP1L 3509.0
MAN2B1 3452.0
C4BPA 3416.0
PSMA7 3408.0
BAIAP2 3397.0
ADGRG3 3366.0
RASGRP1 3344.0
YPEL5 3326.0
B4GALT1 3307.0
DEGS1 3306.0
ARPC1B 3282.0
IL1B 3281.0
PSMA8 3274.0
TLR5 3270.0
SIRPB1 3261.0
SVIP 3256.0
LAT2 3231.0
OLFM4 3210.0
PRKACB 3156.0
TAB1 3094.0
ATG5 3093.0
SYNGR1 3044.0
AGL 3013.0
MUC7 3007.0
PGM1 3001.0
TLR10 2991.0
IFNA5 2962.0
MPO 2949.0
LRRC14 2889.0
FAF2 2839.0
XRCC6 2838.0
PIK3R1 2800.0
C1QA 2793.0
PYGL 2791.0
APAF1 2773.0
LAMTOR3 2763.0
APEH 2723.0
BTRC 2718.0
PRKCD 2716.0
PPP2R1A 2659.0
CD36 2611.0
TXNDC5 2561.0
GAB2 2556.0
WASL 2548.0
LAMTOR2 2473.0
C1QC 2432.0
MAP2K1 2431.0
PCBP2 2413.0
PDXK 2401.0
SERPINB1 2399.0
ATP11B 2388.0
NKIRAS1 2377.0
CD177 2337.0
LILRA3 2327.0
MANBA 2307.0
RHOG 2306.0
SFTPD 2282.0
FCAR 2268.0
ACTG1 2257.0
C5AR1 2240.0
CTSK 2233.0
PGAM1 2212.0
ENPP4 2192.0
PSMB5 2174.0
ADGRE5 2172.0
ATP6V0A1 2169.0
UBE2D2 2156.0
FBXW11 2151.0
AMPD3 2150.0
MIF 2142.0
NOS2 2122.0
GDI2 2103.0
MEF2A 2098.0
PTK2 2095.0
ARL8A 2065.0
VTN 2064.0
ATP6V1B1 2044.0
HSPA1A 2018.0
TLR6 2004.0
VCL 1995.0
PRKCQ 1992.0
CTSZ 1990.0
LCN2 1969.0
TREM2 1968.0
WASF2 1967.0
ALDH3B1 1960.0
TKFC 1939.0
PGM2 1918.0
UBC 1879.0
C9 1858.0
HSPA1B 1849.0
DHX9 1836.0
VAV2 1829.0
POLR3K 1816.0
DEFB110 1796.0
USP14 1773.0
HERC5 1767.0
CREB1 1764.0
ATOX1 1735.0
LAT 1706.0
MUC4 1652.0
DEFB118 1642.0
PSEN1 1609.0
TOMM70 1600.0
MAPK8 1549.0
MYO9B 1546.0
IKBKE 1539.0
RNF125 1503.0
TEC 1500.0
EEF1A1 1448.0
SEM1 1440.0
MMP25 1379.0
ATP6V1G3 1374.0
ATAD3B 1356.0
NCKAP1 1336.0
ADAM10 1321.0
ACLY 1307.0
PSMD3 1303.0
ITPR2 1206.0
IRAG2 1197.0
GHDC 1172.0
ABI2 1171.0
COLEC10 1135.0
PLAUR 1114.0
DOCK2 1089.0
POLR2F 1076.0
TIRAP 1063.0
TUBB 1020.0
SEMG1 981.0
FCER1A 978.0
IFNA16 953.0
POLR2K 936.0
RAB5C 912.0
CYFIP2 869.0
CLEC4A 854.0
AP1M1 852.0
CD300E 813.0
CSTB 802.0
PGLYRP3 754.0
TMEM179B 732.0
DSN1 705.0
TNFAIP3 656.0
ARPC4 644.0
PSME3 614.0
FGG 601.0
SNAP29 599.0
FCGR3B 585.0
ATP6V1B2 576.0
HSP90AA1 550.0
ACTB 524.0
PSMD6 518.0
PIK3C3 497.0
POLR3E 467.0
IRAK3 459.0
REG3A 445.0
PKM 414.0
ELMO2 411.0
POLR3GL 409.0
BRK1 401.0
UBE2N 373.0
PPP3CA 361.0
ATP8A1 327.0
CASP8 299.0
CASP9 286.0
DYNLT1 282.0
CLEC12A 278.0
IST1 254.0
CFD 245.0
MGST1 230.0
EEA1 132.0
PSMD14 114.0
RAF1 29.0
ROCK1 -29.0
ITGAV -45.0
MAP3K7 -53.0
TCIRG1 -72.0
ANPEP -81.0
DEFB129 -106.0
MYO5A -110.0
CEACAM8 -123.0
GOLGA7 -137.0
POLR3B -138.0
NFAM1 -150.0
CLEC4E -168.0
DNM3 -177.0
DBNL -188.0
RAB6A -243.0
NHLRC3 -303.0
TBK1 -310.0
SLC2A5 -336.0
POLR2L -338.0
PROS1 -346.0
TNIP2 -371.0
RPS27A -409.0
GSDME -413.0
TLR3 -441.0
VAV3 -453.0
ARPC3 -464.0
LIMK1 -467.0
NFKBIB -471.0
HK3 -514.0
DERA -517.0
HGSNAT -527.0
ATP6V1F -535.0
CPN1 -538.0
DEFB116 -553.0
NFKB2 -572.0
MYO10 -592.0
ATP6V0A4 -600.0
NLRP3 -608.0
ATP6V0B -677.0
CAPZA1 -682.0
RNF216 -685.0
CLEC4D -703.0
ATG12 -829.0
MAP3K14 -830.0
HRNR -841.0
PTPN4 -845.0
MMP9 -850.0
RAB3A -873.0
P2RX7 -892.0
LTA4H -914.0
GALNS -974.0
IQGAP2 -984.0
ACTR1B -1026.0
PPP2R5D -1030.0
CTSH -1039.0
RAP1B -1064.0
MALT1 -1092.0
VAV1 -1113.0
UBE2D3 -1117.0
UBE2V1 -1122.0
RAB10 -1133.0
PPP3R1 -1168.0
QSOX1 -1215.0
CTSL -1259.0
PSMD5 -1267.0
CPNE1 -1379.0
DSG1 -1384.0
PSMB4 -1390.0
POLR3D -1431.0
DEFB136 -1434.0
ORM1 -1443.0
TIFA -1456.0
NLRX1 -1457.0
PDAP1 -1465.0
GZMM -1485.0
TRAPPC1 -1513.0
MAPK10 -1570.0
FOLR3 -1625.0
NFKB1 -1676.0
EPX -1692.0
GNS -1726.0
KRT1 -1730.0
CYBA -1747.0
SUGT1 -1761.0
MAPK1 -1793.0
CAPZA2 -1804.0
PRTN3 -1818.0
PNP -1869.0
GAA -1881.0
ALDOC -1884.0
ATG7 -1939.0
IFNA13 -1944.0
CCR6 -1960.0
GSDMD -1979.0
PLAC8 -2008.0
CTSB -2042.0
TICAM1 -2054.0
POLR3F -2063.0
COPB1 -2165.0
LTF -2195.0
CXCR2 -2244.0
TIMP2 -2273.0
RAB31 -2301.0
ASAH1 -2304.0
FUCA2 -2329.0
MAPK14 -2356.0
DNAJC13 -2371.0
CFHR5 -2418.0
MAVS -2423.0
VPS35L -2481.0
PPP3CB -2485.0
PIN1 -2502.0
LRRFIP1 -2503.0
RHOA -2508.0
PTX3 -2515.0
NFASC -2521.0
LEAP2 -2523.0
CRCP -2588.0
SRC -2605.0
TNFAIP6 -2621.0
RPS6KA2 -2626.0
ATP6V0E1 -2648.0
CHRNB4 -2657.0
RIGI -2665.0
DOCK1 -2692.0
C7 -2704.0
MUC13 -2747.0
DEFB128 -2770.0
ACTR10 -2775.0
PIGR -2787.0
POLR2H -2828.0
RPS6KA5 -2918.0
CASP10 -2955.0
SIKE1 -2962.0
GYG1 -2998.0
TLR4 -3008.0
ATF1 -3010.0
PSMD7 -3011.0
PI3 -3027.0
CTSA -3047.0
OSTF1 -3061.0
DEFA5 -3103.0
ALOX5 -3106.0
ARPC2 -3116.0
CD14 -3134.0
BPIFB4 -3163.0
TP53 -3175.0
PSMB8 -3188.0
TRIM25 -3199.0
ILF2 -3218.0
GCA -3219.0
PANX1 -3228.0
CD59 -3249.0
ACTR2 -3289.0
IMPDH1 -3296.0
GUSB -3318.0
JUP -3332.0
SCAMP1 -3365.0
CUL1 -3367.0
ITGAM -3427.0
IGF2R -3470.0
LGMN -3503.0
NFATC2 -3514.0
CYLD -3516.0
TREX1 -3543.0
TARM1 -3547.0
MAP2K6 -3585.0
KCMF1 -3591.0
POLR1D -3662.0
LGALS3 -3691.0
AP2A2 -3694.0
ARMC8 -3696.0
PSMB9 -3719.0
PLCG2 -3743.0
CALM1 -3759.0
CASP1 -3763.0
ALPK1 -3775.0
CARD11 -3783.0
WASF3 -3812.0
PSMD8 -3830.0
CFH -3831.0
ARPC1A -3835.0
CRK -3851.0
RASGRP2 -3858.0
ATP6V1C1 -3891.0
POLR3H -3892.0
SLC15A4 -3945.0
FYN -3958.0
DEFB125 -3967.0
CSNK2B -3971.0
RNASET2 -4028.0
PLPP5 -4060.0
SLC27A2 -4094.0
FADD -4120.0
ERP44 -4130.0
UNC13D -4147.0
BRI3 -4194.0
C6orf120 -4232.0
DHX36 -4277.0
CARD9 -4327.0
CYB5R3 -4362.0
IFI16 -4373.0
RETN -4384.0
PAK1 -4397.0
ABL1 -4417.0
TCN1 -4446.0
BPI -4490.0
CHUK -4542.0
ITGAL -4551.0
CD46 -4577.0
COMMD9 -4636.0
FPR1 -4659.0
B2M -4664.0
CFHR4 -4667.0
SIGLEC14 -4680.0
IRF3 -4702.0
PSMC3 -4708.0
PPP2R1B -4709.0
UBR4 -4733.0
PIK3CB -4734.0
NCK1 -4796.0
DPP7 -4837.0
CTSD -4847.0
NBEAL2 -4856.0
CD209 -4896.0
MAP2K4 -4901.0
TANK -4934.0
ARSB -5046.0
IQGAP1 -5081.0
ELMO1 -5111.0
NOS1 -5133.0
MRE11 -5146.0
HRAS -5216.0
STK10 -5224.0
ATP6V0A2 -5227.0
PRKDC -5254.0
TOLLIP -5296.0
C4BPB -5311.0
STBD1 -5363.0
DNAJC3 -5385.0
POLR3C -5410.0
ICAM2 -5428.0
BCL10 -5443.0
ATP6V1C2 -5453.0
WIPF3 -5508.0
TAB2 -5546.0
PLA2G6 -5547.0
CTSS -5598.0
SNAP25 -5603.0
ITLN1 -5606.0
IFIH1 -5614.0
PSMA5 -5619.0
VNN1 -5645.0
ITPR3 -5674.0
CCT2 -5727.0
MVP -5758.0
EP300 -5781.0
CDC42 -5795.0
PPP2CB -5808.0
RPS6KA1 -5825.0
PYGB -5826.0
PRKACA -5856.0
S100A7 -5872.0
AGPAT2 -5889.0
SOS1 -5894.0
TRIM21 -5896.0
ITPR1 -5910.0
RAB5B -6001.0
PSME4 -6007.0
ACTR3 -6056.0
ALAD -6086.0
CASP2 -6094.0
ATP6V1E1 -6111.0
HSPA6 -6123.0
PSMA2 -6134.0
HLA-A -6170.0
PPIE -6192.0
COMMD3 -6243.0
C2 -6264.0
TRPM2 -6318.0
DEFB133 -6337.0
CFB -6404.0
TMEM30A -6436.0
NLRP1 -6500.0
NEU1 -6521.0
SERPINA1 -6524.0
VRK3 -6529.0
CRISPLD2 -6531.0
ELANE -6549.0
PSMC2 -6591.0
AHSG -6606.0
HLA-C -6610.0
CAPN1 -6617.0
PLPP4 -6692.0
SELL -6694.0
ATP6V1H -6730.0
BPIFA1 -6767.0
ECSIT -6786.0
MGAM -6816.0
SPTAN1 -6849.0
MAP2K7 -6939.0
ADAM8 -6950.0
ATP11A -6955.0
KPNB1 -6962.0
NLRC5 -6983.0
MAPKAPK3 -6984.0
CAND1 -7006.0
MYH2 -7010.0
CKAP4 -7014.0
CD58 -7024.0
C5 -7034.0
C3AR1 -7099.0
APP -7137.0
WIPF2 -7148.0
MEFV -7154.0
DEFB113 -7179.0
NFATC1 -7210.0
PLEKHO2 -7224.0
TLR1 -7230.0
SLPI -7240.0
GMFG -7241.0
SFTPA2 -7258.0
PSMF1 -7266.0
CST3 -7267.0
CPN2 -7271.0
RAB4B -7291.0
DEFB134 -7329.0
MS4A2 -7332.0
PKP1 -7360.0
OSCAR -7397.0
NME2 -7402.0
MAPK3 -7507.0
ABCA13 -7536.0
PSMD9 -7539.0
PFKL -7553.0
ATP8B4 -7599.0
UBE2D1 -7612.0
EPPIN-WFDC6 -7626.0
COLEC11 -7644.0
PTPRN2 -7649.0
CXCL1 -7661.0
LAMTOR1 -7679.0
FGA -7698.0
RBSN -7713.0
CD63 -7723.0
MASP2 -7731.0
IKBKB -7739.0
FPR2 -7757.0
RAB18 -7772.0
FUCA1 -7783.0
CREBBP -7802.0
RELB -7819.0
PSMB2 -7879.0
DTX4 -7902.0
SIGIRR -7912.0
PDPK1 -7938.0
NRAS -7941.0
KRAS -7949.0
APRT -7980.0
UBE2M -7999.0
PAFAH1B2 -8008.0
STOM -8047.0
MUCL1 -8048.0
TREM1 -8122.0
CHIT1 -8125.0
BPIFB1 -8126.0
FLG2 -8130.0
MBL2 -8133.0
STK11IP -8135.0
CASP4 -8162.0
PRG2 -8198.0
IRAK4 -8264.0
NLRP4 -8289.0
PSMD2 -8354.0
C4A -8375.5
C4B -8375.5
AGA -8416.0
AIM2 -8419.0
ADA2 -8426.0
MUC5B -8456.0
CCL17 -8458.0
NOD1 -8469.0
UBE2K -8564.0
HLA-B -8565.0
MLEC -8571.0
NCR2 -8614.0
IRF7 -8621.0
LPO -8657.0
DEFB127 -8670.0
DGAT1 -8686.0
C3 -8692.0
CTNNB1 -8712.0
BIRC3 -8740.0
CLEC7A -8746.0
SIGLEC9 -8751.0
TRIM56 -8763.0
CYFIP1 -8773.0
IFNA6 -8796.0
GPI -8888.0
S100A7A -8896.0
RELA -8902.0
EPPIN -8907.0
PAK2 -8910.0
NCF4 -8914.0
CRACR2A -8959.0
PLD2 -8962.0
RAB27A -8969.0
DEFB135 -8973.0
NOD2 -8985.0
CRP -8991.0
CANT1 -9057.0
CDC34 -9070.0
C1S -9127.0
MAPK9 -9162.0
CD4 -9176.0
TRAF2 -9178.0
UBE2L6 -9219.0
MUC16 -9224.0
MUC17 -9243.0
POLR3A -9292.0
MUC5AC -9295.0
C1QB -9313.0
PIK3R4 -9346.0
F2 -9361.0
MUC3A -9371.0
DEFB121 -9442.0
DDX41 -9455.0
HP -9503.0
DEFB1 -9593.0
LYZ -9635.0
MS4A3 -9641.0
A1BG -9656.0
RIPK1 -9673.0
IFNB1 -9735.0
AGER -9754.0
PSMB11 -9770.0
RNASE7 -9789.0
ATP6V0D1 -9812.0
CRISP3 -9829.0
PSMB6 -9876.0
SERPINA3 -9912.0
HBB -9929.0
PECAM1 -9989.0
KLRD1 -10037.0
LILRB3 -10059.0
BPIFB6 -10069.0
CEACAM3 -10104.0
MUC21 -10111.0
HTN1 -10146.0
PSME1 -10185.0
FCN3 -10186.0
LAMP1 -10194.0
PLA2G2A -10203.0
APOB -10246.0
DYNC1H1 -10265.0
NLRC4 -10360.0
NCSTN -10362.0
DDOST -10369.0
BST2 -10372.0
VCP -10379.0
ORM2 -10450.0
ISG15 -10453.0
UBA7 -10458.0
DEFB123 -10489.0
DEFB126 -10564.0
RNASE8 -10686.0
CLEC6A -10737.0
DEFB124 -10802.0
RNASE3 -10870.0
STING1 -10916.0
GNLY -11030.0
SIGLEC5 -11089.0


REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY

REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
1591
set REACTOME_SARS_COV_1_MODULATES_HOST_TRANSLATION_MACHINERY
setSize 33
pANOVA 0.00384
s.dist 0.291
p.adjustANOVA 0.243



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
RPS25 8911
RPS18 8674
RPS2 8671
RPSA 8200
RPS15 8112
RPS6 7877
RPS19 7794
RPS3A 7064
HNRNPA1 5832
RPS24 5215
RPS10 4677
RPS15A 4661
RPS28 3491
RPS14 3317
RPS21 2267

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
RPS25 8911
RPS18 8674
RPS2 8671
RPSA 8200
RPS15 8112
RPS6 7877
RPS19 7794
RPS3A 7064
HNRNPA1 5832
RPS24 5215
RPS10 4677
RPS15A 4661
RPS28 3491
RPS14 3317
RPS21 2267
EEF1A1 1448
FAU 437
RPS16 -365
RPS27A -409
RPS13 -1714
RPS11 -2454
RPS9 -2591
RPS27L -3101
RPS23 -3882
RPS27 -6223
RPS20 -8058
RPS29 -8230
RPS26 -9575


REACTOME_ACTIVATION_OF_C3_AND_C5

REACTOME_ACTIVATION_OF_C3_AND_C5
256
set REACTOME_ACTIVATION_OF_C3_AND_C5
setSize 6
pANOVA 0.00492
s.dist -0.663
p.adjustANOVA 0.299



Top enriched genes

Top 20 genes
GeneID Gene Rank
C3 -8692.0
C4A -8375.5
C4B -8375.5
C5 -7034.0
CFB -6404.0
C2 -6264.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
C3 -8692.0
C4A -8375.5
C4B -8375.5
C5 -7034.0
CFB -6404.0
C2 -6264.0


REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
394
set REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
setSize 30
pANOVA 0.00562
s.dist 0.292
p.adjustANOVA 0.33



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3D 10650
GRAP2 10646
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
CD101 9584
PLCG1 9389
EVL 8994
HLA-DRA 8352
LCP2 6777
VASP 5929
ITK 5227
ENAH 5081
HLA-DRB1 5029
HLA-DQB2 4062
LAT 1706
HLA-DPA1 967
ZAP70 921

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3D 10650
GRAP2 10646
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
CD101 9584
PLCG1 9389
EVL 8994
HLA-DRA 8352
LCP2 6777
VASP 5929
ITK 5227
ENAH 5081
HLA-DRB1 5029
HLA-DQB2 4062
LAT 1706
HLA-DPA1 967
ZAP70 921
FYB1 -1227
HLA-DQB1 -3363
PLCG2 -3743
PAK1 -4397
HLA-DRB5 -4474
NCK1 -4796
HLA-DQA2 -6761
HLA-DPB1 -7634
PAK2 -8910
CD4 -9176


REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM

REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
78
set REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM
setSize 688
pANOVA 0.00607
s.dist 0.0614
p.adjustANOVA 0.341



Top enriched genes

Top 20 genes
GeneID Gene Rank
IFNA21 10747
CCL22 10699
IL23A 10658
GRAP2 10646
RORC 10626
CD27 10615
TNFRSF13C 10555
IL36G 10550
IL20 10535
RAG1 10531
CCR2 10497
LCK 10443
CSF3 10428
IL32 10423
CLCF1 10374
FCER2 10312
IFNA2 10310
IL7R 10247
HLA-DQA1 10235
IFITM3 10232

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
IFNA21 10747.0
CCL22 10699.0
IL23A 10658.0
GRAP2 10646.0
RORC 10626.0
CD27 10615.0
TNFRSF13C 10555.0
IL36G 10550.0
IL20 10535.0
RAG1 10531.0
CCR2 10497.0
LCK 10443.0
CSF3 10428.0
IL32 10423.0
CLCF1 10374.0
FCER2 10312.0
IFNA2 10310.0
IL7R 10247.0
HLA-DQA1 10235.0
IFITM3 10232.0
TNF 10196.0
SAA1 10186.0
MYD88 10180.0
IFNA7 10175.0
S100A12 10170.0
IFNA8 10158.0
CCR1 10150.0
LTA 9970.0
CD86 9958.0
NUP43 9955.0
CCR5 9950.0
TNFSF13 9929.0
IRF5 9927.0
IRF8 9914.0
P4HB 9888.0
IL34 9850.0
IRAK2 9811.0
CD40 9787.0
IFNA1 9736.0
IL10 9658.0
CTSG 9599.0
CD80 9595.0
IL27RA 9580.0
HSP90B1 9493.0
IRF4 9439.0
IL18R1 9395.0
PLCG1 9389.0
RAE1 9369.0
CSF2 9353.0
PSMD12 9352.0
IL7 9297.0
PTPN1 9290.0
FASLG 9288.0
IL18RAP 9248.0
SH2B3 9222.0
MUC1 9080.0
TNFSF13B 8998.0
PTPRJ 8938.0
PSMB10 8921.0
IL2RA 8914.0
IL16 8883.0
CTF1 8786.0
DUSP4 8770.0
BCL2 8749.0
PIK3CD 8742.0
FLT3LG 8737.0
TNFRSF1A 8729.0
BCL2L1 8672.0
HGF 8662.0
LTB 8647.0
IL21R 8626.0
NUP107 8583.0
GRB2 8575.0
IL17RC 8539.0
CNN2 8486.0
IFI30 8474.0
LYN 8472.0
USP18 8447.0
PSMD4 8409.0
PSMC1 8362.0
HLA-DRA 8352.0
SNRPA1 8293.0
CBL 8272.0
DUSP3 8236.0
IL15 8198.0
H3C3 8144.0
DUSP6 8057.0
NKIRAS2 8013.0
PTAFR 8009.0
EIF4G1 7992.0
IL1RN 7985.0
IL19 7956.0
MEF2C 7901.0
HSPA8 7841.0
IL27 7822.0
UBA52 7820.0
STAT6 7801.0
YWHAZ 7793.0
NUP54 7764.0
IL11RA 7735.0
SYK 7703.0
IFNA14 7690.0
CRKL 7676.0
ITGB2 7637.0
ANXA2 7581.0
CSK 7572.0
PELI3 7480.0
TNFRSF1B 7459.0
NUP35 7449.0
IL18BP 7389.0
POMC 7382.0
PSMC6 7360.0
PSMB7 7322.0
SEH1L 7308.0
PSMB1 7304.0
OASL 7294.0
PSME2 7282.0
TRIM45 7277.0
ELOC 7268.0
PSMB3 7246.0
PSMA1 7230.0
LMNB1 7218.0
RAG2 7125.0
EIF4A1 7104.0
MAP2K3 7085.0
IL25 7069.0
MAP3K8 7028.0
CIITA 7015.0
CAMK2G 7003.0
HLA-E 6979.0
SKP1 6937.0
ISG20 6907.0
BLNK 6870.0
IL1R2 6825.0
IL12RB1 6824.0
PSMC5 6773.0
TPR 6756.0
KPNA5 6728.0
TNFRSF6B 6639.0
TRAF6 6579.0
ADAR 6550.0
MYC 6530.0
PSMD1 6519.0
SLA 6513.0
PIK3R2 6512.0
TWIST1 6498.0
H3C8 6449.0
CXCL8 6444.0
SERPINB2 6370.0
IKBIP 6279.0
TRIM14 6224.0
PELI2 6217.0
SOS2 6167.0
POU2F1 6163.0
CFL1 6160.0
CCL2 6126.0
DUSP7 6119.0
RANBP2 6098.0
HLA-G 6086.0
IFNLR1 5976.0
IL6ST 5928.0
BRWD1 5899.0
AAAS 5874.0
GSTO1 5868.0
HMGB1 5850.0
IL26 5824.0
INPP5D 5787.0
ATF2 5785.0
PPP2CA 5736.0
CEBPD 5658.0
JAK1 5648.0
IL1RAP 5606.0
CD70 5595.0
CCL19 5571.0
IL10RB 5517.0
PIK3CA 5509.0
PELI1 5473.0
OAS1 5458.0
IFNGR1 5419.0
PTGS2 5394.0
IL1A 5386.0
PTPN11 5384.0
HCK 5351.0
PPM1B 5348.0
GBP1 5283.0
NUP58 5258.0
NUP210 5237.0
TNFRSF8 5198.0
UBB 5177.0
BIRC2 5170.0
PSMA6 5154.0
PTPN18 5126.0
FOXO3 5124.0
ABCE1 5034.0
HLA-DRB1 5029.0
IL1RL1 5027.0
CCND1 4979.0
SAMHD1 4953.0
EIF4A2 4942.0
UBA3 4937.0
IFI6 4855.0
SOCS1 4802.0
EDAR 4787.0
PSMA3 4777.0
PTK2B 4776.0
BCL2L11 4775.0
CCL20 4752.0
HIF1A 4741.0
YES1 4638.0
AIP 4634.0
N4BP1 4632.0
LBP 4617.0
TRAF3 4587.0
TRIM3 4571.0
MAPK7 4565.0
PSMD13 4481.0
HMOX1 4473.0
IL23R 4449.0
UBE2E1 4394.0
SMAD7 4392.0
CD44 4389.0
PSMD11 4322.0
PSMA4 4297.0
ITGAX 4294.0
CAMK2D 4280.0
TCP1 4271.0
LCP1 4223.0
PPIA 4220.0
IL12RB2 4212.0
PIAS1 4188.0
NFKBIA 4178.0
IL6 4176.0
SHC1 4154.0
IL11 4127.0
STX1A 4126.0
MAPKAPK2 4095.0
NUP133 4093.0
IL15RA 4091.0
HLA-DQB2 4062.0
SDC1 4056.0
H3C11 4016.0
HAVCR2 3993.0
S100B 3910.0
CCL4 3862.0
PTPN6 3857.0
RIPK2 3847.0
FOS 3811.0
IL17C 3808.0
JUN 3797.0
CSF1R 3766.0
MAPK11 3753.0
IL37 3748.0
SOX2 3705.0
PSMC4 3690.0
SOD2 3662.0
CDKN1A 3616.0
IFIT5 3550.0
PDCD4 3511.0
TRIM31 3482.0
PSMA7 3408.0
CAMK2A 3300.0
IL1B 3281.0
PSMA8 3274.0
PTPN5 3201.0
TAB1 3094.0
TNFSF8 3081.0
TRIM2 3075.0
SQSTM1 3052.0
IL12A 3030.0
PIK3CG 2995.0
TNFRSF11A 2967.0
IFNA5 2962.0
LRRC14 2889.0
RAPGEF1 2834.0
CA1 2833.0
FSCN1 2832.0
RNF7 2831.0
POM121C 2812.0
PIK3R1 2800.0
RHOU 2790.0
IL1F10 2788.0
CDKN1B 2756.0
BTRC 2718.0
PRKCD 2716.0
NUP160 2706.0
PTPN23 2694.0
PPP2R1A 2659.0
STX3 2653.0
CD36 2611.0
IL12B 2575.0
IL18 2564.0
IL4 2559.0
GAB2 2556.0
MX1 2536.0
ARF1 2501.0
SP100 2495.0
EIF4G2 2461.0
MAP2K1 2431.0
NKIRAS1 2377.0
ICAM1 2270.0
IL5RA 2254.0
PSMB5 2174.0
UBE2D2 2156.0
FBXW11 2151.0
MIF 2142.0
NOS2 2122.0
IL2RB 2108.0
MEF2A 2098.0
TRIM46 2058.0
GRB10 2017.0
MAP3K3 2013.0
LCN2 1969.0
IL20RA 1937.0
RORA 1893.0
PTPN9 1887.0
UBC 1879.0
PTPN12 1842.0
NDN 1839.0
USP14 1773.0
RBX1 1772.0
HERC5 1767.0
CREB1 1764.0
TNFRSF25 1754.0
THOC5 1665.0
CANX 1597.0
ABL2 1575.0
MAPK8 1549.0
SMAD3 1511.0
TEC 1500.0
KPNA2 1445.0
SEM1 1440.0
STAT4 1407.0
IL4R 1357.0
PSMD3 1303.0
HNRNPA2B1 1168.0
EIF4G3 1115.0
IL36B 1094.0
HLA-DPA1 967.0
IFNA16 953.0
STXBP2 948.0
IL17RE 876.0
ZEB1 816.0
NUP50 736.0
POM121 659.0
PSME3 614.0
MX2 613.0
PRLR 577.0
HSP90AA1 550.0
PSMD6 518.0
EGR1 485.0
IRAK3 459.0
UBE2N 373.0
NCAM1 346.0
CASP8 299.0
IFIT1 213.0
GHR 157.0
PSMD14 114.0
IFNAR1 112.0
NUP88 32.0
IL1R1 -13.0
IL22RA2 -14.0
CCL5 -22.0
MAP3K7 -53.0
TRIM8 -85.0
RNASEL -97.0
KPNA3 -158.0
RALA -237.0
TBK1 -310.0
EIF4E -316.0
TNFRSF11B -318.0
AKT1 -370.0
TNIP2 -371.0
IP6K2 -379.0
RPS27A -409.0
NFKBIB -471.0
IL24 -516.0
NFKB2 -572.0
CAPZA1 -682.0
OSMR -691.0
PTPN2 -735.0
IL20RB -740.0
MAP3K14 -830.0
PTPN4 -845.0
MMP9 -850.0
CUL5 -851.0
COL1A2 -946.0
GBP2 -949.0
IFI27 -994.0
RSAD2 -1001.0
NUP85 -1018.0
PPP2R5D -1030.0
RAP1B -1064.0
TNFSF15 -1104.0
VAV1 -1113.0
UBE2D3 -1117.0
UBE2V1 -1122.0
TNFSF11 -1160.0
ANXA1 -1162.0
TRIM5 -1195.0
SOCS6 -1263.0
GBP4 -1264.0
PSMD5 -1267.0
MT2A -1270.0
KPNA7 -1385.0
PSMB4 -1390.0
SH2B1 -1439.0
KPNA1 -1441.0
TIFA -1456.0
NLRX1 -1457.0
CSF3R -1521.0
MAPK10 -1570.0
NUP188 -1603.0
TRIM6 -1606.0
NFKB1 -1676.0
NEDD4 -1689.0
VEGFA -1763.0
MAPK1 -1793.0
PRTN3 -1818.0
IFNA13 -1944.0
GSDMD -1979.0
STX4 -2002.0
IRS1 -2009.0
FGF2 -2057.0
STAT3 -2059.0
SOCS5 -2074.0
SOCS2 -2139.0
IL1RL2 -2186.0
IL5 -2227.0
CSF1 -2251.0
PIK3R3 -2257.0
IL9 -2303.0
TRIM38 -2345.0
MAPK14 -2356.0
EIF4E3 -2427.0
PIN1 -2502.0
SMARCA4 -2517.0
IL22 -2522.0
EIF2AK2 -2548.0
TRIM62 -2586.0
SRC -2605.0
PTPN13 -2609.0
RPS6KA2 -2626.0
RIGI -2665.0
CASP3 -2726.0
GBP3 -2760.0
CISH -2805.0
CRLF1 -2858.0
RPLP0 -2913.0
RPS6KA5 -2918.0
IL6R -2983.0
ATF1 -3010.0
PSMD7 -3011.0
BCL6 -3062.0
TGFB1 -3077.0
ALOX5 -3106.0
TNFSF14 -3145.0
MTAP -3147.0
TP53 -3175.0
PSMB8 -3188.0
FN1 -3189.0
TRIM25 -3199.0
IL10RA -3227.0
NANOG -3267.0
H3C1 -3282.0
PTPRZ1 -3310.0
PDE12 -3312.0
HLA-DQB1 -3363.0
CUL1 -3367.0
AKT3 -3379.0
ITGAM -3427.0
OAS2 -3435.0
IL17RB -3436.0
CXCL2 -3476.0
NUP62 -3528.0
EDARADD -3545.0
MAP2K6 -3585.0
STAT5B -3603.0
HNRNPDL -3608.0
MMP2 -3616.0
NDC1 -3639.0
ADAM17 -3683.0
TRIM26 -3712.0
PSMB9 -3719.0
HNRNPF -3731.0
PLCG2 -3743.0
IL17F -3747.0
TALDO1 -3750.0
CASP1 -3763.0
ALPK1 -3775.0
IL33 -3824.0
PSMD8 -3830.0
CRK -3851.0
NUP93 -3881.0
OAS3 -3912.0
STAT1 -3915.0
PML -3934.0
FYN -3958.0
TRIM35 -4002.0
TNFSF18 -4026.0
IL17RA -4051.0
LAMA5 -4176.0
IL36RN -4177.0
JAK2 -4375.0
CNTF -4406.0
NUP214 -4467.0
HLA-DRB5 -4474.0
CAMK2B -4518.0
CHUK -4542.0
TNFRSF9 -4570.0
FPR1 -4659.0
B2M -4664.0
TNFSF12 -4674.0
IRF3 -4702.0
PSMC3 -4708.0
PPP2R1B -4709.0
PIK3CB -4734.0
FLT3 -4780.0
IFNG -4820.0
MAP2K4 -4901.0
TNFRSF13B -4921.0
HSPA9 -4946.0
H3C4 -4999.0
STAT5A -5020.0
KPNA4 -5038.0
FOXO1 -5042.0
MMP3 -5045.0
IRS2 -5058.0
NUP37 -5161.0
HRAS -5216.0
OPRM1 -5288.0
TOLLIP -5296.0
TRIM29 -5333.0
TNFRSF12A -5336.0
SUMO1 -5346.0
ARIH1 -5375.0
TRIM22 -5421.0
SOD1 -5433.0
NUP153 -5466.0
TSLP -5482.0
PRL -5497.0
AKT2 -5525.0
NUP42 -5535.0
TAB2 -5546.0
VAMP2 -5591.0
CCL3 -5596.0
SNAP25 -5603.0
PSMA5 -5619.0
JUNB -5643.0
PTPN14 -5648.0
TNFSF9 -5687.0
H3C2 -5710.0
MCL1 -5721.0
TXLNA -5756.0
LIFR -5757.0
TRIM34 -5764.0
IRF2 -5772.0
CDC42 -5795.0
PPP2CB -5808.0
IFNGR2 -5819.0
RPS6KA1 -5825.0
NUP205 -5837.0
PRKACA -5856.0
SOS1 -5894.0
TRIM21 -5896.0
FLNB -6000.0
PSME4 -6007.0
EIF4E2 -6088.0
PSMA2 -6134.0
HLA-A -6170.0
OSM -6190.0
SEC13 -6224.0
S1PR1 -6485.0
VRK3 -6529.0
GBP7 -6572.0
PSMC2 -6591.0
HLA-C -6610.0
HLA-DQA2 -6761.0
CNTFR -6852.0
BATF -6853.0
MAP2K7 -6939.0
KPNB1 -6962.0
TRIM68 -6969.0
NLRC5 -6983.0
MAPKAPK3 -6984.0
APP -7137.0
NUP98 -7138.0
LGALS9 -7201.0
PSMF1 -7266.0
EIF4A3 -7272.0
PITPNA -7442.0
OPRD1 -7452.0
TYK2 -7461.0
MMP1 -7488.0
MAPK3 -7507.0
PSMD9 -7539.0
UBE2D1 -7612.0
TRIM17 -7619.0
HLA-DPB1 -7634.0
CXCL1 -7661.0
HLA-H -7689.0
IKBKB -7739.0
INPPL1 -7799.0
SLA2 -7803.0
RELB -7819.0
IL31RA -7870.0
PSMB2 -7879.0
IRF6 -7901.0
SIGIRR -7912.0
VCAM1 -7929.0
TNFRSF18 -7935.0
NRAS -7941.0
KRAS -7949.0
UBE2M -7999.0
IL17A -8153.0
IL21 -8193.0
PTPN7 -8199.0
IRAK4 -8264.0
XAF1 -8275.0
IFIT2 -8319.0
IRF9 -8321.0
PSMD2 -8354.0
VIM -8420.0
NOD1 -8469.0
ELOB -8474.0
TNFSF4 -8500.0
H3C7 -8506.5
HLA-B -8565.0
IRF7 -8621.0
TNFRSF17 -8632.0
H3C10 -8687.0
IFNL2 -8719.0
BIRC3 -8740.0
ITGB1 -8750.0
IFNA6 -8796.0
TRIM10 -8852.0
RELA -8902.0
PAK2 -8910.0
NUP155 -8920.0
NOD2 -8985.0
LTBR -9080.0
F13A1 -9091.0
IFIT3 -9132.0
IL36A -9153.0
CCL11 -9157.0
MAPK9 -9162.0
CD4 -9176.0
TRAF2 -9178.0
UBE2L6 -9219.0
IFI35 -9238.0
STAT2 -9286.0
GSTA2 -9375.0
IRF1 -9457.0
IFNAR2 -9499.0
GH2 -9535.0
PIM1 -9550.0
IL13 -9583.0
H3C6 -9584.0
JAK3 -9597.0
HLA-F -9657.0
CXCL10 -9659.0
CSF2RB -9682.0
IFNB1 -9735.0
AGER -9754.0
PSMB11 -9770.0
PSMB6 -9876.0
GH1 -10102.0
ALOX15 -10103.0
PSME1 -10185.0
LIF -10190.0
IL22RA1 -10284.0
GATA3 -10345.0
EBI3 -10361.0
BST2 -10372.0
SOCS3 -10374.0
BIRC5 -10419.0
IL2 -10442.0
ISG15 -10453.0
UBA7 -10458.0
IFITM2 -10523.0
GBP6 -10606.0
GBP5 -10610.0
H3C12 -10777.0
IFITM1 -10785.0
IFNL1 -10919.0
TNFRSF4 -10937.0
IL31 -11051.0
IL3 -11083.0
CSH1 -11090.0


REACTOME_METABOLISM_OF_RNA

REACTOME_METABOLISM_OF_RNA
1313
set REACTOME_METABOLISM_OF_RNA
setSize 675
pANOVA 0.00623
s.dist 0.0617
p.adjustANOVA 0.341



Top enriched genes

Top 20 genes
GeneID Gene Rank
APOBEC1 10598
APOBEC3A 10581
APOBEC2 10338
APOBEC3C 10244
NUP43 9955
ZMAT2 9933
TNFSF13 9929
RPS5 9848
RTRAF 9836
RPL12 9835
SRSF1 9830
RPS8 9668
RPS12 9566
PAIP1 9476
RPL23 9464
THOC6 9437
EXOSC6 9427
RPS3 9408
ZFP36 9401
RAE1 9369

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
APOBEC1 10598.0
APOBEC3A 10581.0
APOBEC2 10338.0
APOBEC3C 10244.0
NUP43 9955.0
ZMAT2 9933.0
TNFSF13 9929.0
RPS5 9848.0
RTRAF 9836.0
RPL12 9835.0
SRSF1 9830.0
RPS8 9668.0
RPS12 9566.0
PAIP1 9476.0
RPL23 9464.0
THOC6 9437.0
EXOSC6 9427.0
RPS3 9408.0
ZFP36 9401.0
RAE1 9369.0
PSMD12 9352.0
RPL4 9318.0
PNO1 9298.0
RPS7 9253.0
LENG1 9123.0
WBP11 9103.0
MRM1 9062.0
DHX35 9037.0
PRPF40A 8979.0
RPL7A 8969.0
PSMB10 8921.0
RPS25 8911.0
QTRT1 8895.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
HNRNPR 8618.0
TRMT5 8588.0
NUP107 8583.0
SKIC8 8511.0
RPL13A 8475.5
PNN 8464.0
PTBP1 8434.0
RRP36 8429.0
PSMD4 8409.0
TNKS1BP1 8399.0
ADAT1 8398.0
KRR1 8389.0
PSMC1 8362.0
RPL35A 8332.0
SNRPA1 8293.0
NHP2 8287.0
XPOT 8275.0
ADAT3 8251.0
DHX8 8249.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
DDX39B 8017.0
EIF4G1 7992.0
KHSRP 7954.0
WTAP 7938.0
C1D 7923.0
DCP2 7914.0
SNRPF 7911.0
PAPOLA 7908.0
RPS6 7877.0
HNRNPC 7870.0
LSM11 7860.0
SNRPC 7859.0
HSPA8 7841.0
YBX1 7837.0
UBA52 7820.0
RPS19 7794.0
YWHAZ 7793.0
EXOSC4 7777.0
NUP54 7764.0
RPL39L 7737.0
RPL13 7732.0
SYMPK 7698.0
RPL27A 7634.0
TSEN34 7569.0
ZNF830 7556.0
CSNK1E 7526.0
UTP25 7520.0
U2SURP 7515.0
NUP35 7449.0
RPL22 7445.0
TRMT9B 7444.0
RPLP2 7407.0
ANP32A 7402.0
PSMC6 7360.0
PSMB7 7322.0
SEH1L 7308.0
PSMB1 7304.0
SET 7302.0
PSME2 7282.0
RPPH1 7266.0
PSMB3 7246.0
HNRNPL 7241.0
PSMA1 7230.0
SRSF7 7205.0
POP5 7169.0
EIF4A1 7104.0
RPS3A 7064.0
NOL12 7052.0
CCDC12 7046.0
RPL5 7045.0
CWC15 6996.0
DCAF13 6942.0
CRNKL1 6890.0
IMP4 6835.0
IMP3 6834.0
POLR2D 6812.0
PSMC5 6773.0
TPR 6756.0
CLP1 6723.0
NCL 6713.0
MFAP1 6709.0
HBS1L 6705.0
PUS7 6692.0
UPF1 6659.0
SNRPD3 6621.0
MNAT1 6582.0
ADAR 6550.0
DDX52 6546.0
PSMD1 6519.0
TP53RK 6517.0
RPL32 6495.0
EXOSC3 6473.0
TRIT1 6421.0
UTP11 6390.0
TUT4 6385.0
PAN3 6329.0
RNMT 6261.0
FTSJ3 6172.0
NOP10 6131.0
RANBP2 6098.0
CTU2 6052.0
RPL37 6049.0
NUDT21 6008.0
DDX46 5963.0
PCF11 5956.0
SYF2 5946.0
SF3B4 5933.0
AAAS 5874.0
CTU1 5860.0
TRMT6 5833.0
HNRNPA1 5832.0
HNRNPK 5762.0
PPP2CA 5736.0
RAN 5724.0
NSRP1 5690.0
CSTF1 5674.0
BCAS2 5640.0
GEMIN2 5555.0
POLR2E 5508.0
PPIL3 5477.0
MTREX 5453.0
IK 5411.0
SRSF3 5403.0
CDC40 5364.0
RPP21 5293.0
UTP4 5281.0
NUP58 5258.0
NUP210 5237.0
RPL3L 5231.0
RPS24 5215.0
UTP15 5214.0
TXNL4A 5209.0
UBB 5177.0
PSMA6 5154.0
GNL3 5119.0
RPL23A 5101.0
ADARB1 5085.0
PDCD11 5057.0
RPL15 5038.0
USP39 5003.0
EIF4A2 4942.0
TSR1 4887.0
CPSF6 4876.0
RPL8 4864.0
HNRNPM 4823.0
SRSF10 4822.0
POP7 4786.0
PSMA3 4777.0
RPL6 4762.0
NT5C3B 4744.0
TRMT12 4679.0
RPS10 4677.0
RPS15A 4661.0
RRP9 4593.0
DUS2 4592.0
PPIH 4561.0
POLR2I 4560.0
DDX21 4551.0
TRMT10C 4530.0
ZNF473 4496.0
PSMD13 4481.0
WDR77 4387.0
FAM32A 4385.0
PRPF4 4330.0
PSMD11 4322.0
NSUN4 4302.0
PSMA4 4297.0
NOL11 4278.0
SMG6 4273.0
TRMT112 4240.0
PRKRIP1 4235.0
SARNP 4209.0
RPP40 4208.0
SNRNP25 4190.0
NXF1 4172.0
SF3A2 4125.0
ZBTB8OS 4113.0
MAPKAPK2 4095.0
NUP133 4093.0
MPHOSPH10 4075.0
LSM6 4063.0
BOP1 3984.0
PCBP1 3927.0
RPL21 3866.0
SMG1 3839.0
RPLP1 3770.0
MAPK11 3753.0
IGF2BP1 3746.0
HNRNPU 3742.0
SMG8 3710.0
SUPT5H 3692.0
PSMC4 3690.0
RPL22L1 3661.0
C2orf49 3640.0
GEMIN5 3551.0
RBM22 3537.0
RPL31 3526.0
SRSF8 3507.0
ACIN1 3492.0
RPS28 3491.0
TRMT61A 3488.0
PSMA7 3408.0
METTL3 3362.0
NCBP2 3349.0
RNPC3 3345.0
SNRPB2 3340.0
RPS14 3317.0
PSMA8 3274.0
GSPT1 3260.0
METTL1 3216.0
CPSF2 3200.0
WDR33 3141.0
CSTF2T 3125.0
ALKBH8 3096.0
LSM10 3070.0
ZFP36L1 3029.0
RPP38 2996.0
UBL5 2989.0
IGF2BP2 2983.0
RPL14 2956.0
RPL38 2950.0
WBP4 2880.0
PRORP 2860.0
PPIL1 2853.0
POM121C 2812.0
PES1 2794.0
PRMT5 2766.0
GCFC2 2757.0
PRKCD 2716.0
DIMT1 2707.0
NUP160 2706.0
LSM4 2660.0
PPP2R1A 2659.0
SRSF11 2649.0
EXOSC5 2640.0
GTF2H4 2630.0
FYTTD1 2592.0
PHF5A 2553.0
SNRPN 2552.0
RRP7A 2540.0
HEATR1 2509.0
PCBP2 2413.0
LSM3 2405.0
XPO1 2379.0
RBM8A 2326.0
ADAT2 2294.0
RPS21 2267.0
PLRG1 2266.0
TCERG1 2250.0
SMG7 2175.0
PSMB5 2174.0
OSGEP 2146.0
DDX20 2124.0
LSM5 2106.0
HSPA1A 2018.0
PABPC1 2008.0
CNOT4 1978.0
RPL9 1911.0
UBC 1879.0
PRPF38A 1877.0
DHX9 1836.0
RPL18 1830.0
SNUPN 1827.0
RPL7 1760.0
SNW1 1745.0
HNRNPD 1671.0
THOC5 1665.0
SF1 1603.0
WDR4 1601.0
DIS3 1581.0
RPL11 1544.0
GEMIN4 1501.0
CNOT8 1483.0
SEM1 1440.0
PHAX 1401.0
TRMT11 1400.0
ZCRB1 1364.0
METTL14 1360.0
RPL36 1314.0
PSMD3 1303.0
EPRS1 1271.0
WDR12 1264.0
SNRPA 1208.0
SART1 1196.0
HNRNPA2B1 1168.0
POLR2F 1076.0
SDE2 1073.0
RIOK3 1067.0
DHX15 1022.0
TSEN15 1014.0
CNOT7 1009.0
CWC27 942.0
POLR2K 936.0
SNIP1 863.0
TYW5 814.0
PRKCA 759.0
UPF3A 752.0
NUP50 736.0
PPP2R2A 710.0
POM121 659.0
PSME3 614.0
ISG20L2 593.0
PSMD6 518.0
CCNH 498.0
RPL26 455.0
CDKAL1 450.0
FAU 437.0
TGS1 369.0
SNU13 366.0
IGF2BP3 256.0
PRPF18 252.0
RBM25 152.0
RPL28 128.0
PSMD14 114.0
GEMIN7 101.0
LUC7L3 87.0
RBM28 73.0
NUP88 32.0
RPP25 -11.0
FCF1 -17.0
EDC3 -155.0
TRA2B -167.0
MRM3 -194.0
WDR46 -203.0
UPF2 -293.0
EIF4E -316.0
POLR2L -338.0
RPS16 -365.0
AKT1 -370.0
EIF4B -397.0
RPS27A -409.0
TNPO1 -465.0
RBM5 -468.0
PRPF19 -552.0
DDX6 -581.0
EFTUD2 -594.0
RBM7 -610.0
THG1L -614.0
RPL37A -651.0
GTF2F2 -676.0
SF3A1 -733.0
EBNA1BP2 -827.0
SNRNP48 -831.0
CPSF3 -844.0
SNRPD2 -885.0
SRSF6 -895.0
SRRT -929.0
CDC5L -937.0
NUP85 -1018.0
APOBEC3B -1106.0
RPL41 -1150.0
TRMT61B -1224.0
PSMD5 -1267.0
ZMAT5 -1271.0
UTP3 -1290.0
POLR2C -1312.0
SRSF5 -1346.0
SAP18 -1358.0
PSMB4 -1390.0
PPIG -1400.0
YWHAB -1452.0
MPHOSPH6 -1500.0
CSTF3 -1502.0
YJU2 -1530.0
GTF2H3 -1549.0
RPL17 -1554.0
TPRKB -1585.0
NUP188 -1603.0
DDX1 -1611.0
RBM42 -1627.0
RIOK2 -1647.0
NSUN6 -1691.0
RPS13 -1714.0
RPL18A -1756.0
EXOSC10 -1774.0
RPL10A -1862.0
LSM1 -1879.0
PPIL2 -1903.0
CNOT11 -1913.0
GAR1 -1924.0
POLR2B -1946.0
NAT10 -1952.0
EMG1 -1971.0
WDR36 -2044.0
APOBEC4 -2067.0
ZC3H11A -2081.0
CASC3 -2082.0
WDR3 -2111.0
SNRPD1 -2155.0
DDX42 -2202.0
EXOSC8 -2203.0
CHTOP -2208.0
DDX23 -2216.0
RBM17 -2222.0
SNRNP70 -2231.0
PPP1R8 -2271.0
GTF2H1 -2280.0
DNAJC8 -2319.0
HNRNPH1 -2335.0
MAPK14 -2356.0
ETF1 -2383.0
THADA -2407.0
DCP1A -2428.0
SRRM2 -2438.0
RPS11 -2454.0
PNRC2 -2457.0
PDCD7 -2561.0
TRMT1 -2582.0
RPL26L1 -2590.0
RPS9 -2591.0
DDX49 -2599.0
CDK7 -2633.0
SF3B5 -2638.0
DDX47 -2639.0
SMG5 -2682.0
POP4 -2708.0
SMNDC1 -2712.0
GTF2H5 -2723.0
SF3B1 -2724.0
NOL9 -2758.0
APOBEC3H -2808.0
POLR2H -2828.0
RPLP0 -2913.0
HSPB1 -2935.0
DDX5 -2961.0
SF3B3 -2967.0
A1CF -2991.0
PSMD7 -3011.0
GTF2F1 -3086.0
RPS27L -3101.0
THOC1 -3149.0
NOP14 -3151.0
BUD23 -3170.0
BUD31 -3187.0
PSMB8 -3188.0
PELP1 -3271.0
DHX37 -3376.0
RNPS1 -3387.0
LCMT2 -3398.0
POLR2G -3408.0
RPP14 -3430.0
PATL1 -3479.0
NUP62 -3528.0
CACTIN -3562.0
QTRT2 -3571.0
NDC1 -3639.0
PSMB9 -3719.0
HNRNPF -3731.0
SRSF12 -3757.0
RPL19 -3774.0
TRDMT1 -3791.0
PSMD8 -3830.0
PRCC -3843.0
NUP93 -3881.0
RPS23 -3882.0
XRN2 -3987.0
RBM39 -4004.0
DCPS -4010.0
POP1 -4011.0
ISY1 -4047.0
MTERF4 -4063.0
RNGTT -4154.0
CPSF1 -4172.0
BUD13 -4190.0
PABPN1 -4270.0
TYW1 -4271.0
NCBP1 -4344.0
NOP58 -4352.0
MTO1 -4392.0
SKIC3 -4416.0
SENP3 -4425.0
TRMT10A -4466.0
NUP214 -4467.0
EXOSC1 -4499.0
SF3A3 -4568.0
CNOT9 -4656.0
CWC25 -4660.0
UTP6 -4668.0
PSMC3 -4708.0
FIP1L1 -4745.0
PRPF3 -4753.0
NOP2 -4806.0
CNOT6L -4863.0
GTPBP3 -4987.0
BYSL -4990.0
CNOT10 -5034.0
SMU1 -5050.0
MAGOH -5117.0
PPIL4 -5139.0
NUP37 -5161.0
CNOT3 -5188.0
TRMT13 -5260.0
CCAR1 -5276.0
DHX16 -5304.0
SNRNP35 -5360.0
CWC22 -5368.0
TUT7 -5388.0
PRPF31 -5406.0
EDC4 -5456.0
NOC4L -5462.0
NUP153 -5466.0
RCL1 -5473.0
SRSF4 -5499.0
SNRPB -5512.0
ELAVL1 -5513.0
NUP42 -5535.0
SRRM1 -5563.0
PSMA5 -5619.0
ERCC3 -5620.0
CWF19L2 -5644.0
PAN2 -5658.0
POLDIP3 -5737.0
NUP205 -5837.0
WDR75 -5860.0
PSME4 -6007.0
DCP1B -6091.0
CNOT1 -6128.0
PSMA2 -6134.0
WDR70 -6145.0
PUS1 -6187.0
PPIE -6192.0
SNRPG -6195.0
UTP18 -6198.0
CLNS1A -6202.0
RPS27 -6223.0
SEC13 -6224.0
LSM2 -6237.0
GPATCH1 -6368.0
EXOSC9 -6377.0
THUMPD1 -6391.0
LSM8 -6399.0
SLBP -6530.0
XRN1 -6560.0
PSMC2 -6591.0
WDR43 -6602.0
NSUN2 -6608.0
NIP7 -6632.0
ALYREF -6636.0
TRMT44 -6641.0
AQR -6655.0
UTP20 -6685.0
CNOT6 -6738.0
PPWD1 -6788.0
CTNNBL1 -6836.0
MRM2 -6885.0
TSEN2 -6903.0
SMN1 -6927.5
SMN2 -6927.5
TSEN54 -6993.0
CSNK1D -7003.0
CNOT2 -7028.0
RIOK1 -7051.0
PWP2 -7057.0
U2AF1L4 -7058.0
HNRNPA3 -7073.0
TFB1M -7077.0
GEMIN6 -7129.0
NUP98 -7138.0
PRPF8 -7147.0
CPSF7 -7176.0
SF3B2 -7191.0
RPL30 -7243.0
PSMF1 -7266.0
EIF4A3 -7272.0
TSR3 -7298.0
SKIC2 -7361.0
DHX38 -7362.0
GLE1 -7382.0
RPL29 -7404.0
EXOSC7 -7460.0
MAGOHB -7473.0
LTV1 -7481.0
XAB2 -7509.0
PSMD9 -7539.0
NXT1 -7561.0
DDX39A -7598.0
ELAC2 -7655.0
NOB1 -7738.0
BMS1 -7861.0
PSMB2 -7879.0
SUGP1 -7885.0
C9orf78 -7921.0
RPP30 -7922.0
RPS20 -8058.0
SNRNP27 -8072.0
TYW3 -8084.0
SMG9 -8106.0
FAM98B -8108.0
TFIP11 -8177.0
RPS29 -8230.0
SRSF9 -8272.0
THOC7 -8280.0
U2AF2 -8310.0
LSM7 -8336.0
PSMD2 -8354.0
NOP56 -8363.0
RPL27 -8392.0
PARN -8407.0
PUF60 -8432.0
SRSF2 -8489.0
PUS3 -8512.0
ERI1 -8581.0
RPL35 -8625.0
SNRPE -8673.0
RRP1 -8735.0
CHERP -8737.0
NUP155 -8920.0
CPSF4 -8976.0
URM1 -9052.0
PRPF6 -9059.0
TEX10 -9124.0
FBL -9278.0
TBL3 -9294.0
RTCB -9396.0
DDX41 -9455.0
SNRNP40 -9529.0
POLR2A -9547.0
RPS26 -9575.0
ERCC2 -9718.0
NOL6 -9758.0
PSMB11 -9770.0
WDR18 -9813.0
TRNT1 -9817.0
PSMB6 -9876.0
SNRNP200 -9902.0
EXOSC2 -9930.0
SF3B6 -9952.0
RPL10L -10035.0
FUS -10039.0
PSME1 -10185.0
TRMU -10327.0
POLR2J -10455.0
SLU7 -10466.0
UTP14C -10541.0
THOC3 -11185.0


REACTOME_TNFR1_MEDIATED_CERAMIDE_PRODUCTION

REACTOME_TNFR1_MEDIATED_CERAMIDE_PRODUCTION
920
set REACTOME_TNFR1_MEDIATED_CERAMIDE_PRODUCTION
setSize 6
pANOVA 0.0065
s.dist 0.642
p.adjustANOVA 0.343



Top enriched genes

Top 20 genes
GeneID Gene Rank
TNF 10196
TNFRSF1A 8729
RACK1 8385
SMPD2 5611
SMPD3 5286
NSMAF 2753

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
TNF 10196
TNFRSF1A 8729
RACK1 8385
SMPD2 5611
SMPD3 5286
NSMAF 2753


REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
1135
set REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES
setSize 353
pANOVA 0.00669
s.dist 0.084
p.adjustANOVA 0.343



Top enriched genes

Top 20 genes
GeneID Gene Rank
AMT 10634
GNMT 10092
MAT1A 10021
RPS5 9848
RPL12 9835
GATM 9781
PRODH 9692
RPS8 9668
BBOX1 9589
HOGA1 9581
RPS12 9566
RPL23 9464
RPS3 9408
PSMD12 9352
RPL4 9318
RPS7 9253
RPL7A 8969
LIPT2 8937
PSMB10 8921
RPS25 8911

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
AMT 10634.0
GNMT 10092.0
MAT1A 10021.0
RPS5 9848.0
RPL12 9835.0
GATM 9781.0
PRODH 9692.0
RPS8 9668.0
BBOX1 9589.0
HOGA1 9581.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
RPL7A 8969.0
LIPT2 8937.0
PSMB10 8921.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
NAALAD2 8759.0
RPL36AL 8722.5
TYR 8689.0
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
PSMD4 8409.0
NDUFAB1 8384.0
TSHB 8363.0
PSMC1 8362.0
GCDH 8337.0
RPL35A 8332.0
SUOX 8328.0
RPSA 8200.0
HGD 8160.0
RPS15 8112.0
RPL34 8063.0
GADL1 8042.0
BHMT2 7999.0
SERINC1 7953.0
FOLH1 7921.0
GLUD1 7892.0
NAT8L 7888.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
PAOX 7775.0
RPL39L 7737.0
RPL13 7732.0
RIMKLB 7666.0
RPL27A 7634.0
CKB 7593.0
NAGS 7573.0
DLST 7495.0
RPL22 7445.0
RPLP2 7407.0
PSMC6 7360.0
PSMB7 7322.0
PSMB1 7304.0
PSME2 7282.0
PSMB3 7246.0
PSMA1 7230.0
RPS3A 7064.0
RPL5 7045.0
CARNMT1 7002.0
OAZ1 6827.0
PSMC5 6773.0
DMGDH 6707.0
HYKK 6682.0
ARG1 6592.0
PSMD1 6519.0
RPL32 6495.0
ALDH7A1 6488.0
HAAO 6468.0
AZIN2 6371.0
PHYKPL 6327.0
GAMT 6211.0
ADO 6203.0
GPT2 6124.0
QDPR 6085.0
CPS1 6075.0
RPL37 6049.0
PAH 5915.0
PYCR3 5904.0
OAZ3 5895.0
GPT 5684.0
CGA 5558.0
CARNS1 5527.0
PIPOX 5483.0
SRR 5465.0
GLS 5422.0
AIMP1 5405.0
RPL3L 5231.0
RPS24 5215.0
PSMA6 5154.0
TH 5130.0
RPL23A 5101.0
RPL15 5038.0
CSAD 5017.0
GCAT 4970.0
OAT 4925.0
RPL8 4864.0
PSMA3 4777.0
RPL6 4762.0
DUOX2 4738.0
RPS10 4677.0
RPS15A 4661.0
DIO3 4509.0
PSMD13 4481.0
SLC7A5 4477.0
LARS1 4450.0
ODC1 4412.0
AHCY 4369.0
ARG2 4363.0
IYD 4327.0
PSMD11 4322.0
SARDH 4312.0
PSMA4 4297.0
MRI1 4252.0
CKMT1B 4221.0
DARS1 4144.0
SERINC5 4083.0
GOT1 4009.0
DIO1 3962.0
TPH2 3937.0
RPL21 3866.0
GLDC 3850.0
RPLP1 3770.0
CRYM 3757.0
PSMC4 3690.0
RPL22L1 3661.0
SLC36A4 3584.0
RPL31 3526.0
RPS28 3491.0
AASS 3438.0
PSMA7 3408.0
SEPSECS 3377.0
RPS14 3317.0
PSMA8 3274.0
LIAS 3168.0
SQOR 3131.0
CTH 3054.0
PYCR2 2982.0
RPL14 2956.0
AMDHD1 2955.0
RPL38 2950.0
SERINC3 2879.0
SLC44A1 2792.0
HNMT 2735.0
GLUL 2721.0
SLC3A2 2582.0
PSTK 2560.0
TAT 2538.0
ASNS 2429.0
SMOX 2354.0
AZIN1 2349.0
BCAT1 2312.0
RPS21 2267.0
SECISBP2 2238.0
DLD 2228.0
PSMB5 2174.0
FMO1 2153.0
SLC25A15 2001.0
OAZ2 1946.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
BCKDHB 1647.0
AADAT 1629.0
RPL11 1544.0
SEM1 1440.0
GRHPR 1422.0
SLC25A12 1377.0
MPST 1372.0
SLC25A2 1328.0
RPL36 1314.0
PSMD3 1303.0
PHGDH 1280.0
EPRS1 1271.0
GOT2 1202.0
NMRAL1 1149.0
SLC25A13 1100.0
GLS2 1097.0
DHTKD1 1024.0
TXNRD1 984.0
PRODH2 828.0
SEPHS2 767.0
SLC25A10 694.0
PNMT 690.0
ASPA 645.0
PSME3 614.0
AANAT 555.0
PSMD6 518.0
HPD 479.0
RPL26 455.0
FAU 437.0
LIPT1 175.0
TPH1 138.0
RPL28 128.0
PSMD14 114.0
PDHB 106.0
ACADSB 82.0
BCKDHA -199.0
AUH -271.0
RPS16 -365.0
RPS27A -409.0
IL4I1 -438.0
RPL37A -651.0
ETHE1 -665.0
CKMT2 -671.0
TST -699.0
AGXT2 -954.0
SLC25A21 -1013.0
RPL41 -1150.0
ALDH6A1 -1238.0
PSMD5 -1267.0
RARS1 -1308.0
PSMB4 -1390.0
DDC -1397.0
SLC6A11 -1463.0
ACAT1 -1495.0
APIP -1498.0
PSPH -1506.0
RPL17 -1554.0
SDSL -1642.0
RPS13 -1714.0
RPL18A -1756.0
KARS1 -1845.0
RPL10A -1862.0
ACAD8 -2036.0
TDO2 -2189.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
SHMT1 -2619.0
ASRGL1 -2632.0
OGDH -2753.0
RPLP0 -2913.0
SERINC2 -2978.0
PSMD7 -3011.0
IARS1 -3084.0
RPS27L -3101.0
MTAP -3147.0
PSMB8 -3188.0
AFMID -3236.0
HIBADH -3306.0
HDC -3377.0
PYCR1 -3416.0
PPM1K -3513.0
PSMB9 -3719.0
RPL19 -3774.0
PSMD8 -3830.0
RPS23 -3882.0
SLC25A44 -3899.0
DUOX1 -4035.0
KYNU -4220.0
HAL -4245.0
PXMP2 -4261.0
DDO -4449.0
ENOPH1 -4523.0
MTR -4602.0
PSMC3 -4708.0
ALDH4A1 -4739.0
PAPSS1 -4768.0
RIDA -4801.0
SERINC4 -4824.0
RIMKLA -4846.0
PDHX -4905.0
PCBD1 -5001.0
IVD -5008.0
MCCC1 -5070.0
KMO -5217.0
PAPSS2 -5232.0
EEFSEC -5252.0
TSTD1 -5345.0
IDO1 -5411.0
DCT -5445.0
DBT -5479.0
CKM -5552.0
AMD1 -5578.0
PSMA5 -5619.0
SLC5A5 -5685.0
HAO1 -5851.0
HIBCH -5938.0
SLC6A12 -5977.0
GSTZ1 -5995.0
ASS1 -6004.0
PSME4 -6007.0
PSMA2 -6134.0
EEF1E1 -6152.0
AIMP2 -6219.0
RPS27 -6223.0
IDO2 -6239.0
CDO1 -6241.0
UROC1 -6295.0
OCA2 -6308.0
CHDH -6388.0
FAH -6478.0
PDHA2 -6578.0
PSMC2 -6591.0
AGMAT -6609.0
ADI1 -6631.0
INMT -6839.0
TYRP1 -6896.0
ACMSD -6957.0
KYAT3 -7044.0
AGXT -7178.0
RPL30 -7243.0
PSMF1 -7266.0
MTRR -7339.0
RPL29 -7404.0
SRM -7470.0
BCAT2 -7513.0
GSR -7533.0
PSMD9 -7539.0
DIO2 -7785.0
DLAT -7824.0
PSMB2 -7879.0
ASPG -7942.0
GCSH -7944.0
RPS20 -8058.0
RPS29 -8230.0
PSMD2 -8354.0
SLC6A7 -8366.0
RPL27 -8392.0
MCCC2 -8574.0
NQO1 -8593.0
RPL35 -8625.0
MARS1 -8722.0
SLC45A2 -8998.0
ALDH9A1 -9043.0
BHMT -9089.0
DBH -9168.0
FTCD -9173.0
ALDH18A1 -9185.0
DAO -9222.0
PSAT1 -9283.0
BCKDK -9288.0
TXN2 -9289.0
RPS26 -9575.0
ASL -9628.0
NNMT -9653.0
TPO -9728.0
PSMB11 -9770.0
SCLY -9864.0
PSMB6 -9876.0
KYAT1 -9970.0
SDS -9994.0
RPL10L -10035.0
PSME1 -10185.0
ECHS1 -10490.0


REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS
768
set REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS
setSize 18
pANOVA 0.00708
s.dist -0.367
p.adjustANOVA 0.352



Top enriched genes

Top 20 genes
GeneID Gene Rank
SLC6A20 -9498
SLC6A9 -9418
SLC6A18 -8653
SLC6A7 -8366
SLC6A3 -7725
SLC22A1 -7645
SLC6A12 -5977
SLC22A2 -5565
SLC6A19 -4881
SLC6A5 -3664
SLC6A2 -3247
SLC6A13 -2906
SLC18A2 -1561
SLC6A11 -1463
SLC6A1 -1377
SLC6A6 4
SLC18A1 1847
SLC6A15 3382

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SLC6A20 -9498
SLC6A9 -9418
SLC6A18 -8653
SLC6A7 -8366
SLC6A3 -7725
SLC22A1 -7645
SLC6A12 -5977
SLC22A2 -5565
SLC6A19 -4881
SLC6A5 -3664
SLC6A2 -3247
SLC6A13 -2906
SLC18A2 -1561
SLC6A11 -1463
SLC6A1 -1377
SLC6A6 4
SLC18A1 1847
SLC6A15 3382


REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY
628
set REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize 348
pANOVA 0.00753
s.dist -0.0834
p.adjustANOVA 0.364



Top enriched genes

Top 20 genes
GeneID Gene Rank
OR4K15 -11186
OR52L1 -11173
OR8H3 -11171
OR5K3 -11165
OR52E6 -11121
OR8A1 -11109
OR5D13 -11035
OR2G2 -11016
OR5M8 -11015
OR4A47 -10968
OR4X2 -10943
OR10G8 -10898
OR2K2 -10852
OR5M9 -10839
OR1I1 -10822
OR56B4 -10806
OR2C1 -10791
OR8B8 -10778
OR1J1 -10749
OR2L5 -10695

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
OR4K15 -11186.0
OR52L1 -11173.0
OR8H3 -11171.0
OR5K3 -11165.0
OR52E6 -11121.0
OR8A1 -11109.0
OR5D13 -11035.0
OR2G2 -11016.0
OR5M8 -11015.0
OR4A47 -10968.0
OR4X2 -10943.0
OR10G8 -10898.0
OR2K2 -10852.0
OR5M9 -10839.0
OR1I1 -10822.0
OR56B4 -10806.0
OR2C1 -10791.0
OR8B8 -10778.0
OR1J1 -10749.0
OR2L5 -10695.0
OR8D1 -10689.0
OR1Q1 -10684.0
OR7D4 -10677.0
OR2AG2 -10662.0
OR14A16 -10659.0
OR5J2 -10596.0
OR52H1 -10595.0
OR10AD1 -10579.0
OR4S1 -10559.0
OR3A1 -10526.0
OR9A2 -10506.0
OR5D14 -10485.0
OR8J1 -10477.0
OR1L1 -10401.0
OR2W3 -10398.0
OR2M4 -10387.0
OR5AN1 -10386.0
OR5C1 -10375.0
OR2V2 -10349.0
OR4E2 -10325.0
OR4C3 -10318.0
OR6P1 -10312.0
OR8B4 -10275.0
OR10H1 -10223.0
OR7D2 -10216.0
OR1L4 -10193.0
OR10V1 -10166.0
OR1N2 -10157.0
OR10G4 -10135.0
OR13J1 -10131.0
OR5A2 -10079.0
OR6B3 -10058.0
OR52I2 -9969.0
OR2AP1 -9962.0
OR6C68 -9923.0
OR2C3 -9793.0
OR5D18 -9764.0
OR2T12 -9760.0
OR52I1 -9753.0
OR4C16 -9687.0
OR6V1 -9668.0
OR13G1 -9616.0
OR6M1 -9598.0
OR6C75 -9566.0
OR52E4 -9540.0
OR1D2 -9528.0
OR2M5 -9469.0
OR51V1 -9462.0
OR1J4 -9412.0
OR1G1 -9378.0
OR10A6 -9334.0
OR4M1 -9306.0
OR7C1 -9298.0
RTP2 -9248.0
OR1S2 -9193.0
OR4C6 -9104.0
OR1L8 -9060.0
OR51I2 -9003.0
OR6C76 -8931.0
OR1B1 -8915.0
OR5M11 -8881.0
OR2D3 -8761.0
OR10G2 -8721.0
OR6C6 -8594.0
OR7C2 -8584.0
OR6T1 -8583.0
OR5B2 -8582.0
OR10G3 -8554.0
OR14I1 -8542.0
OR5B21 -8522.0
OR2A5 -8317.0
OR5H1 -8305.0
OR5L1 -8258.0
OR2B11 -8189.0
OR5K4 -8183.0
OR1M1 -8173.0
OR5AC2 -8119.0
OR1J2 -8054.0
OR4K13 -7962.0
OR4X1 -7814.0
OR51T1 -7808.0
OR5AS1 -7735.0
OR52R1 -7716.0
OR1N1 -7559.0
OR7G3 -7505.0
OR2M2 -7486.0
OR8D4 -7455.0
OR10Q1 -7365.0
OR2A12 -7322.0
OR51D1 -7312.0
OR13D1 -7284.0
OR51Q1 -7218.0
OR7G2 -7134.0
OR7A5 -7125.0
OR2B3 -7060.0
OR2Z1 -7047.0
OR4K14 -7001.0
OR7E24 -6930.0
OR9I1 -6819.0
OR5AP2 -6723.0
OR2B2 -6659.0
OR11G2 -6651.0
LHX2 -6619.0
OR11H6 -6568.0
OR10A3 -6481.0
OR4D2 -6410.0
OR4D11 -6384.5
OR4C15 -6359.0
OR4N5 -6292.0
OR2A2 -6048.0
OR13A1 -5917.0
OR10A4 -5904.0
OR5A1 -5888.0
OR4K2 -5858.0
OR11H4 -5776.0
OR56A5 -5589.0
OR1L3 -5554.0
OR2D2 -5379.0
OR8K3 -5369.0
OR52D1 -5364.0
OR6N2 -5353.0
OR4F6 -5292.0
OR6A2 -5243.0
OR10K2 -5098.0
OR1A1 -5007.0
OR8U3 -5003.0
GNG13 -4650.0
OR9G1 -4624.5
OR9G9 -4624.5
OR51B5 -4561.0
OR2S2 -4441.0
OR5D16 -4179.0
OR6C1 -4155.0
OR56A4 -4031.0
OR2G3 -3885.0
OR5T2 -3795.0
OR52B6 -3780.0
OR6F1 -3778.0
OR2Y1 -3670.0
ANO2 -3389.0
OR8S1 -3261.0
OR52K2 -3239.0
OR10P1 -3009.0
OR8U8 -2942.0
OR4F15 -2887.0
OR51I1 -2842.0
OR5AU1 -2820.0
ADCY3 -2818.0
OR10J5 -2785.0
OR10H3 -2662.0
OR1F1 -2600.0
OR1K1 -2450.0
OR2F1 -2369.0
RTP1 -2051.0
OR4L1 -1980.0
OR12D3 -1776.0
OR4A15 -1745.0
OR8J3 -1735.0
OR5I1 -1558.0
REEP1 -1493.0
OR51M1 -1453.0
OR10X1 -1372.0
OR11L1 -1229.0
OR12D2 -1206.0
OR8B12 -1176.0
OR13F1 -1148.0
OR2T1 -1016.0
OR10J1 -977.0
OR2AG1 -872.0
OR2H1 -871.0
OR7A10 -764.0
OR2T6 -616.0
OR2T4 -560.0
OR8U1 -354.0
OR2T33 -180.0
OR52N1 -117.0
OR10G7 -40.0
OR5P3 -4.0
OR51B4 116.0
OR4B1 185.0
OR51F2 240.0
CNGB1 395.0
OR6C65 492.0
OR51B2 805.0
OR9Q2 817.0
OR5T1 822.0
OR52A5 1078.0
GNB1 1436.0
OR2F2 1447.0
OR4K17 1477.0
OR1E1 1543.0
OR1L6 1643.0
OR2J2 1792.0
OR10Z1 1835.0
OR2W1 1971.0
OR5F1 2126.0
OR9Q1 2193.0
OR2T11 2290.0
OR8B2 2329.0
OR3A3 2638.0
OR2L13 2688.0
OR10T2 2885.0
OR6B1 3119.0
OR52J3 3134.0
OR2L8 3331.0
OR2B6 3339.0
OR52E8 3437.0
OR4D5 3508.0
OR13C4 3534.0
OR5M10 3652.0
OR2AK2 3720.0
OR5V1 3803.0
OR5B3 3875.0
OR6N1 4139.0
OR1C1 4222.0
OR7A17 4232.0
OR10H5 4366.0
OR6X1 4457.0
OR6S1 4567.0
GNAL 4625.0
OR10AG1 4635.0
OR10G9 4645.0
OR5K2 4720.0
OR4A16 4883.0
OR6C70 4987.0
OR6K6 5048.0
OR8G1 5226.0
OR51S1 5230.0
OR13C8 5325.0
OR52N2 5333.0
OR5H2 5378.0
OR10W1 5618.0
OR5W2 5721.0
OR51E2 5916.0
OR5T3 5994.0
LDB1 6040.0
EBF1 6205.0
OR5M1 6216.0
OR11A1 6366.0
OR52W1 6367.0
OR51A2 6396.0
OR10A2 6538.0
OR5B17 6629.0
OR5L2 6694.0
OR4C46 6769.0
OR2M3 6788.0
OR8D2 6823.0
OR51L1 6833.0
OR14J1 6845.0
OR14C36 6856.0
OR10C1 6882.0
OR51B6 6983.0
OR13C3 7179.0
OR56A3 7193.0
OR9G4 7293.0
OR1E2 7373.0
OR5H15 7443.0
OR7G1 7484.0
OR51A7 7678.0
OR10H2 7738.0
OR10H4 7799.0
OR6C3 7832.0
OR2T8 7867.0
OR8K1 7872.0
OR51E1 8028.0
OR4A5 8119.0
OR2T27 8126.0
OR13C9 8360.0
OR6K2 8443.0
OR6Y1 8455.0
OR4K5 8465.0
OR4C45 8716.0
CNGA4 8720.0
OR5M3 8802.0
OR8G5 8877.0
OR2AT4 8927.0
OR6B2 9022.0
OR1S1 9051.0
OR56B1 9091.0
OR8H1 9094.0
OR2A14 9269.0
OR5H6 9302.0
OR8K5 9305.0
OR10A5 9327.0
OR52B2 9348.0
OR5K1 9392.0
OR51F1 9460.0
OR4D1 9469.0
OR52A1 9592.0
OR5B12 9644.0
OR9K2 9672.0
OR51G1 9766.0
OR6C4 9770.0
OR10J3 9841.0
OR2G6 9913.0
OR6C2 9941.0
OR1A2 9968.0
OR52K1 10046.0
OR5P2 10056.0
OR5AK2 10065.0
OR6C74 10077.0
OR6K3 10134.0
OR4C12 10145.0
OR10K1 10156.0
OR4N2 10179.0
OR9A4 10192.0
OR4K1 10193.0
OR52M1 10219.0
OR4D10 10222.0
OR56A1 10240.0
OR3A2 10259.0
OR2AE1 10266.0
OR2V1 10290.0
OR13C2 10298.0
OR4D6 10301.0
OR10A7 10379.0
OR5AR1 10439.0
OR2H2 10453.0
OR51G2 10484.0
OR52E2 10576.0
OR2M7 10617.0
OR2L2 10641.0
OR2L3 10644.0
OR6Q1 10657.0
OR4D9 10683.0
OR2T3 10697.0
OR8I2 10711.0
OR10S1 10726.0


REACTOME_PI3K_AKT_SIGNALING_IN_CANCER

REACTOME_PI3K_AKT_SIGNALING_IN_CANCER
477
set REACTOME_PI3K_AKT_SIGNALING_IN_CANCER
setSize 103
pANOVA 0.00842
s.dist 0.15
p.adjustANOVA 0.384



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
NR4A1 9496
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105
FGFR3 7187

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
NR4A1 9496
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105
FGFR3 7187
FGF17 7101
PIK3R2 6512
RPS6KB2 6157
ERBB3 5779
TRAT1 5711
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF7 5358
PRR5 5200
FGF18 5144
FOXO3 5124
KLB 4842
PIK3AP1 4602
FGF6 4287
PDGFRA 4105
FGF10 4019
AKT1S1 3978
FGF3 3835
KL 3743
CDKN1A 3616
FRS2 3246
MET 3117
FGFR1 2972
PIK3R1 2800
CDKN1B 2756
GAB2 2556
ESR1 2393
RHOG 2306
GSK3A 2051
CREB1 1764
FGF1 1692
FGF23 1055
FGFR2 929
ESR2 800
KIT 446
CASP9 286
FGF8 199
MDM2 76
AKT1 -370
NRG3 -470
PTEN -898
MAPKAP1 -919
ERBB4 -921
VAV1 -1113
GSK3B -1274
GAB1 -1551
NRG1 -1678
NRG4 -1796
IRS1 -2009
FGF2 -2057
PIK3R3 -2257
STRN -2298
BAD -2389
SRC -2605
FGF9 -2778
EGF -3230
NRG2 -3275
FOXO6 -3278
AKT3 -3379
FYN -3958
CHUK -4542
PIK3CB -4734
FLT3 -4780
TGFA -4899
FOXO1 -5042
IRS2 -5058
MLST8 -5409
TSC2 -5491
AKT2 -5525
FGF19 -5544
RICTOR -6117
EREG -6751
KITLG -6856
MTOR -7026
EGFR -7457
PDGFA -7896
PDPK1 -7938
FGFR4 -8535
EPGN -9669
FGF22 -10022
ICOS -10796


REACTOME_PD_1_SIGNALING

REACTOME_PD_1_SIGNALING
646
set REACTOME_PD_1_SIGNALING
setSize 21
pANOVA 0.00875
s.dist 0.33
p.adjustANOVA 0.384



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3D 10650
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
HLA-DRA 8352
CSK 7572
PDCD1 7110
PTPN11 5384
CD274 5257
HLA-DRB1 5029
HLA-DQB2 4062
PTPN6 3857
HLA-DPA1 967
HLA-DQB1 -3363
HLA-DRB5 -4474
PDCD1LG2 -5927
HLA-DQA2 -6761
HLA-DPB1 -7634

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3D 10650
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
HLA-DRA 8352
CSK 7572
PDCD1 7110
PTPN11 5384
CD274 5257
HLA-DRB1 5029
HLA-DQB2 4062
PTPN6 3857
HLA-DPA1 967
HLA-DQB1 -3363
HLA-DRB5 -4474
PDCD1LG2 -5927
HLA-DQA2 -6761
HLA-DPB1 -7634
CD4 -9176


REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
1150
set REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S
setSize 53
pANOVA 0.00886
s.dist 0.208
p.adjustANOVA 0.384



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
EIF2S2 8976
RPS25 8911
RPS18 8674
RPS2 8671
RPSA 8200
EIF2S1 8154
RPS15 8112
EIF4G1 7992
RPS6 7877
RPS19 7794
EIF4A1 7104
RPS3A 7064
RPS24 5215
EIF4A2 4942
EIF3E 4934

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
EIF2S2 8976
RPS25 8911
RPS18 8674
RPS2 8671
RPSA 8200
EIF2S1 8154
RPS15 8112
EIF4G1 7992
RPS6 7877
RPS19 7794
EIF4A1 7104
RPS3A 7064
RPS24 5215
EIF4A2 4942
EIF3E 4934
RPS10 4677
RPS15A 4661
EIF4H 4356
RPS28 3491
RPS14 3317
EIF3I 3026
RPS21 2267
PABPC1 2008
EIF3J 499
FAU 437
EIF3L -197
EIF4E -316
RPS16 -365
EIF4B -397
RPS27A -409
EIF3A -1255
EIF3F -1373
EIF3D -1713
RPS13 -1714
EIF3M -1717
RPS11 -2454
EIF3G -2455
RPS9 -2591
RPS27L -3101
EIF3B -3790
RPS23 -3882
EIF3K -4513
RPS27 -6223
EIF3H -6415
RPS20 -8058
RPS29 -8230
RPS26 -9575
EIF4EBP1 -9694


REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE

REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE
453
set REACTOME_SYNTHESIS_OF_16_20_HYDROXYEICOSATETRAENOIC_ACIDS_HETE
setSize 9
pANOVA 0.0089
s.dist 0.504
p.adjustANOVA 0.384



Top enriched genes

Top 20 genes
GeneID Gene Rank
CYP4A11 10274
CYP2C9 8627
CYP2C19 7743
CYP2C8 7073
CYP1B1 6831
CYP2U1 5106
CYP4F2 3738
CYP1A2 1457
CYP1A1 -3081

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CYP4A11 10274
CYP2C9 8627
CYP2C19 7743
CYP2C8 7073
CYP1B1 6831
CYP2U1 5106
CYP4F2 3738
CYP1A2 1457
CYP1A1 -3081


REACTOME_TCR_SIGNALING

REACTOME_TCR_SIGNALING
391
set REACTOME_TCR_SIGNALING
setSize 113
pANOVA 0.0107
s.dist 0.139
p.adjustANOVA 0.452



Top enriched genes

Top 20 genes
GeneID Gene Rank
CD3D 10650
GRAP2 10646
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
CD101 9584
PLCG1 9389
PSMD12 9352
EVL 8994
PTPRJ 8938
PSMB10 8921
PSMD4 8409
PSMC1 8362
HLA-DRA 8352
PAG1 8211
UBA52 7820
CSK 7572
PSMC6 7360

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
CD3D 10650
GRAP2 10646
LCK 10443
HLA-DQA1 10235
CD3G 10100
CD247 10029
CD3E 9720
CD101 9584
PLCG1 9389
PSMD12 9352
EVL 8994
PTPRJ 8938
PSMB10 8921
PSMD4 8409
PSMC1 8362
HLA-DRA 8352
PAG1 8211
UBA52 7820
CSK 7572
PSMC6 7360
PSMB7 7322
PSMB1 7304
PSME2 7282
PSMB3 7246
PSMA1 7230
SKP1 6937
LCP2 6777
PSMC5 6773
PTPRC 6767
TRAF6 6579
PSMD1 6519
PIK3R2 6512
VASP 5929
INPP5D 5787
TRAT1 5711
PIK3CA 5509
ITK 5227
UBB 5177
PSMA6 5154
ENAH 5081
HLA-DRB1 5029
PSMA3 4777
PSMD13 4481
PSMD11 4322
PSMA4 4297
NFKBIA 4178
HLA-DQB2 4062
RIPK2 3847
PSMC4 3690
PSMA7 3408
PSMA8 3274
PIK3R1 2800
BTRC 2718
PSMB5 2174
UBE2D2 2156
FBXW11 2151
PRKCQ 1992
UBC 1879
LAT 1706
SEM1 1440
PTPN22 1386
PSMD3 1303
HLA-DPA1 967
ZAP70 921
PSME3 614
PSMD6 518
UBE2N 373
PSMD14 114
MAP3K7 -53
RPS27A -409
PTEN -898
MALT1 -1092
UBE2V1 -1122
FYB1 -1227
PSMD5 -1267
PSMB4 -1390
NFKB1 -1676
PSMD7 -3011
PSMB8 -3188
HLA-DQB1 -3363
CUL1 -3367
PSMB9 -3719
PLCG2 -3743
CARD11 -3783
PSMD8 -3830
PAK1 -4397
HLA-DRB5 -4474
CHUK -4542
PSMC3 -4708
PIK3CB -4734
NCK1 -4796
BCL10 -5443
TAB2 -5546
PSMA5 -5619
PSME4 -6007
PSMA2 -6134
PSMC2 -6591
HLA-DQA2 -6761
PSMF1 -7266
PSMD9 -7539
UBE2D1 -7612
HLA-DPB1 -7634
IKBKB -7739
PSMB2 -7879
PDPK1 -7938
PSMD2 -8354
RELA -8902
PAK2 -8910
CDC34 -9070
CD4 -9176
PSMB11 -9770
PSMB6 -9876
PSME1 -10185


REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR
747
set REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR
setSize 24
pANOVA 0.0116
s.dist 0.298
p.adjustANOVA 0.467



Top enriched genes

Top 20 genes
GeneID Gene Rank
GNGT2 10434
GNB4 9755
GNA11 9035
GNG8 8537
GNGT1 8261
GNB3 8048
GNG5 7561
GNA13 7388
GNAQ 6710
AAMP 5559
GNG10 5123
TBXA2R 3992
GNG12 2935
GNG2 1520
GNB1 1436
GNB5 1331
GNG7 424
GNA14 34
GNA15 -1242
GNB2 -3370

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GNGT2 10434
GNB4 9755
GNA11 9035
GNG8 8537
GNGT1 8261
GNB3 8048
GNG5 7561
GNA13 7388
GNAQ 6710
AAMP 5559
GNG10 5123
TBXA2R 3992
GNG12 2935
GNG2 1520
GNB1 1436
GNB5 1331
GNG7 424
GNA14 34
GNA15 -1242
GNB2 -3370
GNG4 -3453
GNG11 -4479
GNG13 -4650
GNG3 -7910


REACTOME_CONJUGATION_OF_BENZOATE_WITH_GLYCINE

REACTOME_CONJUGATION_OF_BENZOATE_WITH_GLYCINE
265
set REACTOME_CONJUGATION_OF_BENZOATE_WITH_GLYCINE
setSize 6
pANOVA 0.0119
s.dist -0.593
p.adjustANOVA 0.467



Top enriched genes

Top 20 genes
GeneID Gene Rank
GLYAT -10306
GLYATL2 -8799
ACSM2B -8716
GLYATL1 -7712
ACSM1 -4187
GLYATL3 -813

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
GLYAT -10306
GLYATL2 -8799
ACSM2B -8716
GLYATL1 -7712
ACSM1 -4187
GLYATL3 -813


REACTOME_PI_3K_CASCADE_FGFR3

REACTOME_PI_3K_CASCADE_FGFR3
947
set REACTOME_PI_3K_CASCADE_FGFR3
setSize 17
pANOVA 0.0119
s.dist 0.352
p.adjustANOVA 0.467



Top enriched genes

Top 20 genes
GeneID Gene Rank
FGF20 9459
GRB2 8575
FGFR3 7187
FGF17 7101
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF18 5144
FRS2 3246
PIK3R1 2800
FGF1 1692
FGF23 1055
FGF8 199
GAB1 -1551
FGF2 -2057
FGF9 -2778

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
FGF20 9459
GRB2 8575
FGFR3 7187
FGF17 7101
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF18 5144
FRS2 3246
PIK3R1 2800
FGF1 1692
FGF23 1055
FGF8 199
GAB1 -1551
FGF2 -2057
FGF9 -2778


REACTOME_RRNA_PROCESSING

REACTOME_RRNA_PROCESSING
1148
set REACTOME_RRNA_PROCESSING
setSize 192
pANOVA 0.0133
s.dist 0.104
p.adjustANOVA 0.489



Top enriched genes

Top 20 genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
EXOSC6 9427.0
RPS3 9408.0
RPL4 9318.0
PNO1 9298.0
RPS7 9253.0
MRM1 9062.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RRP36 8429.0

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RPS5 9848.0
RPL12 9835.0
RPS8 9668.0
RPS12 9566.0
RPL23 9464.0
EXOSC6 9427.0
RPS3 9408.0
RPL4 9318.0
PNO1 9298.0
RPS7 9253.0
MRM1 9062.0
RPL7A 8969.0
RPS25 8911.0
RPL24 8827.0
RPL3 8779.0
RPL36AL 8722.5
RPS18 8674.0
RPS2 8671.0
RPL13A 8475.5
RRP36 8429.0
KRR1 8389.0
RPL35A 8332.0
NHP2 8287.0
RPSA 8200.0
RPS15 8112.0
RPL34 8063.0
C1D 7923.0
RPS6 7877.0
UBA52 7820.0
RPS19 7794.0
EXOSC4 7777.0
RPL39L 7737.0
RPL13 7732.0
RPL27A 7634.0
CSNK1E 7526.0
UTP25 7520.0
RPL22 7445.0
RPLP2 7407.0
RPS3A 7064.0
NOL12 7052.0
RPL5 7045.0
DCAF13 6942.0
IMP4 6835.0
IMP3 6834.0
NCL 6713.0
DDX52 6546.0
RPL32 6495.0
EXOSC3 6473.0
UTP11 6390.0
FTSJ3 6172.0
NOP10 6131.0
RPL37 6049.0
MTREX 5453.0
RPP21 5293.0
UTP4 5281.0
RPL3L 5231.0
RPS24 5215.0
UTP15 5214.0
GNL3 5119.0
RPL23A 5101.0
PDCD11 5057.0
RPL15 5038.0
TSR1 4887.0
RPL8 4864.0
RPL6 4762.0
RPS10 4677.0
RPS15A 4661.0
RRP9 4593.0
DDX21 4551.0
TRMT10C 4530.0
NSUN4 4302.0
NOL11 4278.0
TRMT112 4240.0
RPP40 4208.0
MPHOSPH10 4075.0
BOP1 3984.0
RPL21 3866.0
RPLP1 3770.0
RPL22L1 3661.0
RPL31 3526.0
RPS28 3491.0
RPS14 3317.0
RPP38 2996.0
RPL14 2956.0
RPL38 2950.0
PRORP 2860.0
PES1 2794.0
DIMT1 2707.0
EXOSC5 2640.0
RRP7A 2540.0
HEATR1 2509.0
RPS21 2267.0
RPL9 1911.0
RPL18 1830.0
RPL7 1760.0
DIS3 1581.0
RPL11 1544.0
RPL36 1314.0
WDR12 1264.0
RIOK3 1067.0
ISG20L2 593.0
RPL26 455.0
FAU 437.0
SNU13 366.0
RPL28 128.0
RBM28 73.0
RPP25 -11.0
FCF1 -17.0
MRM3 -194.0
WDR46 -203.0
RPS16 -365.0
RPS27A -409.0
RPL37A -651.0
EBNA1BP2 -827.0
RPL41 -1150.0
UTP3 -1290.0
MPHOSPH6 -1500.0
RPL17 -1554.0
RIOK2 -1647.0
RPS13 -1714.0
RPL18A -1756.0
EXOSC10 -1774.0
RPL10A -1862.0
GAR1 -1924.0
NAT10 -1952.0
EMG1 -1971.0
WDR36 -2044.0
WDR3 -2111.0
EXOSC8 -2203.0
RPS11 -2454.0
RPL26L1 -2590.0
RPS9 -2591.0
DDX49 -2599.0
DDX47 -2639.0
NOL9 -2758.0
RPLP0 -2913.0
RPS27L -3101.0
NOP14 -3151.0
BUD23 -3170.0
PELP1 -3271.0
DHX37 -3376.0
RPP14 -3430.0
RPL19 -3774.0
RPS23 -3882.0
XRN2 -3987.0
MTERF4 -4063.0
NOP58 -4352.0
SENP3 -4425.0
EXOSC1 -4499.0
UTP6 -4668.0
NOP2 -4806.0
BYSL -4990.0
NOC4L -5462.0
RCL1 -5473.0
WDR75 -5860.0
UTP18 -6198.0
RPS27 -6223.0
EXOSC9 -6377.0
THUMPD1 -6391.0
WDR43 -6602.0
NIP7 -6632.0
UTP20 -6685.0
MRM2 -6885.0
CSNK1D -7003.0
RIOK1 -7051.0
PWP2 -7057.0
TFB1M -7077.0
RPL30 -7243.0
TSR3 -7298.0
RPL29 -7404.0
EXOSC7 -7460.0
LTV1 -7481.0
ELAC2 -7655.0
NOB1 -7738.0
BMS1 -7861.0
RPP30 -7922.0
RPS20 -8058.0
RPS29 -8230.0
NOP56 -8363.0
RPL27 -8392.0
ERI1 -8581.0
RPL35 -8625.0
RRP1 -8735.0
TEX10 -9124.0
FBL -9278.0
TBL3 -9294.0
RPS26 -9575.0
NOL6 -9758.0
WDR18 -9813.0
EXOSC2 -9930.0
RPL10L -10035.0
UTP14C -10541.0


REACTOME_NERVOUS_SYSTEM_DEVELOPMENT

REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
1536
set REACTOME_NERVOUS_SYSTEM_DEVELOPMENT
setSize 552
pANOVA 0.0133
s.dist 0.0616
p.adjustANOVA 0.489



Top enriched genes

Top 20 genes
GeneID Gene Rank
MPZ 10250
HOXA2 10095
PRKAR2A 10044
EFNB3 10043
SCN7A 9869
RPS5 9848
SCN11A 9845
CD72 9844
RPL12 9835
RPS8 9668
SEMA4D 9617
RPS12 9566
RPL23 9464
RPS3 9408
PLCG1 9389
TYROBP 9384
PSMD12 9352
RPL4 9318
RPS7 9253
GFRA3 9198

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
MPZ 10250.0
HOXA2 10095.0
PRKAR2A 10044.0
EFNB3 10043.0
SCN7A 9869.0
RPS5 9848.0
SCN11A 9845.0
CD72 9844.0
RPL12 9835.0
RPS8 9668.0
SEMA4D 9617.0
RPS12 9566.0
RPL23 9464.0
RPS3 9408.0
PLCG1 9389.0
TYROBP 9384.0
PSMD12 9352.0
RPL4 9318.0
RPS7 9253.0
GFRA3 9198.0
TUBB6 9197.0
PRKACG 9090.0
PLXND1 9058.0
KIF4B 9004.0
EVL 8994.0
RPL7A 8969.0
ITGA5 8926.0
PSMB10 8921.0
RPS25 8911.0
ABLIM3 8881.0
RPL24 8827.0
RPL3 8779.0
PIK3CD 8742.0
RPL36AL 8722.5
TUBA8 8697.0
RPS18 8674.0
RPS2 8671.0
GRB2 8575.0
MYL12A 8534.0
RPL13A 8475.5
LYN 8472.0
PSMD4 8409.0
ERBB2 8390.0
PSMC1 8362.0
RPL35A 8332.0
GRB7 8233.0
RPSA 8200.0
EFNA5 8171.0
SIAH1 8170.0
RPS15 8112.0
RAC1 8105.0
NAB2 8100.0
RPL34 8063.0
FLRT3 8034.0
EIF4G1 7992.0
ARPC5 7928.0
APH1B 7903.0
RPS6 7877.0
PRX 7865.0
HSPA8 7841.0
UBA52 7820.0
DLG4 7818.0
RPS19 7794.0
CLTCL1 7776.0
RPL39L 7737.0
RPL13 7732.0
ARHGEF11 7717.0
MYL12B 7696.0
RPL27A 7634.0
SPTB 7558.0
PLXNB1 7554.0
HSP90AB1 7509.0
SCN1A 7497.0
RPL22 7445.0
EPHB3 7434.0
RPLP2 7407.0
DNM1 7364.0
PSMC6 7360.0
PSMB7 7322.0
RASA1 7313.0
PSMB1 7304.0
TUBB4B 7295.0
PSME2 7282.0
ELOC 7268.0
PSMB3 7246.0
PSMA1 7230.0
CDK5 7122.0
RPS3A 7064.0
RPL5 7045.0
YAP1 6969.0
SCN1B 6968.0
VLDLR 6954.0
EFNA4 6933.0
TRPC6 6931.0
PDLIM7 6893.0
DOK2 6853.0
PSMC5 6773.0
PTPRC 6767.0
SEMA3A 6645.0
SCN2A 6599.0
SPTA1 6540.0
PSMD1 6519.0
PIK3R2 6512.0
RPL32 6495.0
EPHA7 6457.0
ARTN 6442.0
UNC5B 6358.0
SOS2 6167.0
CFL1 6160.0
RPL37 6049.0
LDB1 6040.0
VASP 5929.0
PFN1 5829.0
SCN3B 5797.0
POU3F2 5741.0
COL5A2 5709.0
RGMA 5708.0
DNM2 5639.0
SEMA4A 5626.0
KCNQ3 5598.0
PIK3CA 5509.0
RHOB 5437.0
PTPN11 5384.0
RPL3L 5231.0
RPS24 5215.0
UBB 5177.0
PSMA6 5154.0
CSNK2A1 5137.0
RPL23A 5101.0
ENAH 5081.0
EPHA2 5061.0
RPL15 5038.0
HDAC2 4994.0
PAK6 4955.0
RPL8 4864.0
CLTB 4856.0
SCN4B 4832.0
COL4A3 4784.0
PSMA3 4777.0
RPL6 4762.0
TLN1 4754.0
GPC1 4696.0
RPS10 4677.0
RPS15A 4661.0
YES1 4638.0
SPTBN2 4578.0
TUBB3 4574.0
MAPK7 4565.0
USP33 4521.0
SDCBP 4511.0
PSMD13 4481.0
HJV 4447.0
MAPK13 4434.0
CXCR4 4383.0
PSMD11 4322.0
TUBA1A 4298.0
PSMA4 4297.0
PLXNA2 4295.0
MYH9 4268.0
ITSN1 4250.0
SHC1 4154.0
SCN2B 4020.0
NTN1 4005.0
RPL21 3866.0
GFRA4 3778.0
NUMB 3777.0
RPLP1 3770.0
MAPK11 3753.0
ABLIM1 3730.0
MAPK12 3715.0
PSMC4 3690.0
RPL22L1 3661.0
TRPC3 3542.0
CAP1 3528.0
RPL31 3526.0
NGEF 3504.0
RPS28 3491.0
SCD5 3456.0
DOK1 3424.0
PSMA7 3408.0
PLXNA4 3391.0
NCBP2 3349.0
RPS14 3317.0
ARPC1B 3282.0
PSMA8 3274.0
GSPT1 3260.0
PLXNC1 3251.0
FRS2 3246.0
ALCAM 3225.0
PRKACB 3156.0
MET 3117.0
TRPC4 3024.0
FGFR1 2972.0
RPL14 2956.0
RPL38 2950.0
PIK3R1 2800.0
TIAM1 2621.0
SPTBN1 2557.0
GAB2 2556.0
WASL 2548.0
ARHGEF7 2547.0
EFNA2 2516.0
CACNA1S 2504.0
NRP1 2491.0
MAP2K1 2431.0
RBM8A 2326.0
RPS21 2267.0
ACTG1 2257.0
ITGA2B 2256.0
ITGA1 2241.0
ITGB3 2218.0
CACNA1G 2198.0
ADGRV1 2187.0
PSMB5 2174.0
LAMA2 2164.0
RRAS 2159.0
PTK2 2095.0
NRCAM 2084.0
MYL6 2045.0
ITGA2 2029.0
GRB10 2017.0
PABPC1 2008.0
PRKCQ 1992.0
TREM2 1968.0
RPL9 1911.0
UBC 1879.0
GAP43 1862.0
RPL18 1830.0
VAV2 1829.0
ARHGEF28 1808.0
RBX1 1772.0
CREB1 1764.0
RPL7 1760.0
MYH10 1757.0
SEMA3E 1714.0
ST8SIA4 1685.0
PSEN1 1609.0
EFNA3 1585.0
ABL2 1575.0
MAPK8 1549.0
MYO9B 1546.0
RPL11 1544.0
SEM1 1440.0
TUBB2B 1351.0
SLIT2 1327.0
ADAM10 1321.0
RPL36 1314.0
PSMD3 1303.0
TRIO 1294.0
SEMA6A 1266.0
EPHA3 1113.0
DPYSL4 966.0
NELL2 946.0
CXCL12 927.0
TUBA4A 874.0
WWTR1 827.0
DOK5 806.0
PRKCA 759.0
UPF3A 752.0
ARHGAP39 735.0
POU3F1 703.0
GFRA2 673.0
DOK4 660.0
ARPC4 644.0
PSME3 614.0
CHL1 609.0
SPTBN5 586.0
GDNF 557.0
HSP90AA1 550.0
ACTB 524.0
PSMD6 518.0
ANK1 469.0
RPL26 455.0
FAU 437.0
RELN 388.0
CLASP2 362.0
RND1 353.0
NCAM1 346.0
SRGAP3 237.0
RPL28 128.0
PSMD14 114.0
EZR 79.0
NCAN 61.0
LAMC1 23.0
NCK2 3.0
CACNB3 -23.0
ROCK1 -29.0
SLIT1 -32.0
ITGAV -45.0
SCN8A -93.0
ARHGEF12 -136.0
DNM3 -177.0
DLG1 -259.0
UPF2 -293.0
COL9A2 -304.0
COL2A1 -339.0
SPTBN4 -343.0
AGAP2 -349.0
AP2B1 -353.0
RPS16 -365.0
SH3GL2 -366.0
CYP51A1 -405.0
RPS27A -409.0
CACNB4 -424.0
CLTC -436.0
VAV3 -453.0
ARPC3 -464.0
LIMK1 -467.0
EGR2 -486.0
LIMK2 -488.0
GRIN2B -540.0
CACNB1 -555.0
MYO10 -592.0
RPL37A -651.0
CNTN1 -706.0
ROBO1 -717.0
AKAP5 -834.0
MMP9 -850.0
ADGRG6 -894.0
RET -923.0
CACNA1I -956.0
UNC5D -1022.0
SRGAP1 -1059.0
MAG -1076.0
SIAH2 -1103.0
LHX9 -1132.0
RPL41 -1150.0
EPHA1 -1154.0
COL6A1 -1253.0
PSMD5 -1267.0
GSK3B -1274.0
PSMB4 -1390.0
SDC2 -1392.0
COL9A3 -1442.0
EFNB2 -1462.0
EFNA1 -1504.0
GAB1 -1551.0
RPL17 -1554.0
CLTA -1565.0
PAK4 -1568.0
PIP5K1C -1573.0
EPHB6 -1673.0
EPHB1 -1685.0
NTN4 -1705.0
RPS13 -1714.0
KALRN -1722.0
ISL1 -1737.0
UTRN -1755.0
RPL18A -1756.0
MAPK1 -1793.0
SCN10A -1797.0
TUBB1 -1801.0
MSI1 -1808.0
DPYSL3 -1834.0
RPL10A -1862.0
RGMB -2056.0
COL4A1 -2060.0
CASC3 -2082.0
RAP1GAP -2088.0
TUBA4B -2137.0
LAMB1 -2176.0
PIK3R3 -2257.0
LHX4 -2259.0
DPYSL2 -2263.0
MAPK14 -2356.0
SREBF2 -2357.0
AGRN -2359.0
SEMA7A -2361.0
NRP2 -2370.0
ETF1 -2383.0
CNTNAP1 -2392.0
EPHA6 -2414.0
RPS11 -2454.0
UNC5A -2459.0
DCC -2460.0
PPP3CB -2485.0
RHOA -2508.0
SMARCA4 -2517.0
NFASC -2521.0
SCN4A -2549.0
RPL26L1 -2590.0
RPS9 -2591.0
SRC -2605.0
RPS6KA2 -2626.0
SLIT3 -2690.0
DOCK1 -2692.0
ANK2 -2743.0
AP2A1 -2796.0
CACNA1D -2829.0
FES -2886.0
RPLP0 -2913.0
RPS6KA5 -2918.0
CACNA1C -2964.0
SCN9A -2970.0
PSMD7 -3011.0
EPHA5 -3067.0
RPS27L -3101.0
ARPC2 -3116.0
GRIN1 -3137.0
SCN5A -3138.0
PAK5 -3141.0
APH1A -3160.0
PSMB8 -3188.0
LYPLA2 -3210.0
CAP2 -3222.0
ACTR2 -3289.0
CLASP1 -3290.0
RNPS1 -3387.0
ANK3 -3412.0
MMP2 -3616.0
NAB1 -3651.0
AP2A2 -3694.0
PSMB9 -3719.0
COL6A3 -3724.0
COL9A1 -3740.0
RPL19 -3774.0
PSMD8 -3830.0
ARPC1A -3835.0
SEMA5A -3876.0
RPS23 -3882.0
FYN -3958.0
CSNK2B -3971.0
ARHGAP35 -3993.0
PFN2 -4208.0
CUL2 -4238.0
TRPC1 -4258.0
SEMA6D -4259.0
COL6A6 -4284.0
ROBO2 -4298.0
EPHB2 -4301.0
ITGA9 -4306.0
NCBP1 -4344.0
CSNK2A2 -4372.0
PAK1 -4397.0
ABL1 -4417.0
TRPC7 -4455.0
DAB1 -4537.0
RDX -4609.0
GFRA1 -4619.0
PRNP -4679.0
CACNB2 -4705.0
PSMC3 -4708.0
COL3A1 -4725.0
PIK3CB -4734.0
RANBP9 -4760.0
NCK1 -4796.0
EPHA4 -4902.0
SRGAP2 -4972.0
UNC5C -5005.0
SCN3A -5055.0
IRS2 -5058.0
MAGOH -5117.0
DOK6 -5160.0
COL4A2 -5180.0
MYL9 -5185.0
COL5A3 -5212.0
HRAS -5216.0
TUBB8 -5218.0
TUBAL3 -5391.0
NEO1 -5420.0
ROCK2 -5476.0
DPYSL5 -5503.0
PSMA5 -5619.0
AP2S1 -5627.0
CNTN2 -5668.0
TUBB2A -5670.0
CDC42 -5795.0
COL6A5 -5796.0
RPS6KA1 -5825.0
RHOC -5842.0
PRKACA -5856.0
SOS1 -5894.0
PSME4 -6007.0
ACTR3 -6056.0
DSCAM -6074.0
RPS6KA4 -6096.0
SHTN1 -6105.0
PSMA2 -6134.0
RPS27 -6223.0
CRMP1 -6248.0
NRTN -6263.0
ABLIM2 -6345.0
PSEN2 -6355.0
PLXNA1 -6420.0
ROBO3 -6444.0
TUBB4A -6514.0
DAG1 -6515.0
PSMC2 -6591.0
LHX2 -6619.0
EPHA8 -6628.0
CDK5R1 -6696.0
PMP22 -6720.0
SPTAN1 -6849.0
COL4A4 -6876.0
DSCAML1 -6956.0
EPHA10 -7117.0
RPL30 -7243.0
PSMF1 -7266.0
EIF4A3 -7272.0
TEAD1 -7394.0
RPL29 -7404.0
TUBA1B -7437.0
PITPNA -7442.0
EGFR -7457.0
MAGOHB -7473.0
MAPK3 -7507.0
PSMD9 -7539.0
MYH14 -7841.0
PSMB2 -7879.0
NRAS -7941.0
KRAS -7949.0
TUBA3C -7971.0
MBP -8025.0
COL5A1 -8057.0
RPS20 -8058.0
PSENEN -8163.0
MYH11 -8164.0
EPHB4 -8182.0
RPS29 -8230.0
COL6A2 -8332.0
ST8SIA2 -8346.0
PSMD2 -8354.0
RPL27 -8392.0
CNTN6 -8395.0
SOX10 -8449.0
ELOB -8474.0
FARP2 -8482.0
PTPRA -8592.0
SHC3 -8616.0
RPL35 -8625.0
CACNA1H -8647.0
ITGB1 -8750.0
PAK2 -8910.0
HMGCR -8947.0
MAP2K2 -9159.0
KCNQ2 -9231.0
AP2M1 -9265.0
ITGA10 -9322.0
LHX3 -9465.0
TUBA3E -9521.0
RPS26 -9575.0
TUBA1C -9607.0
GIT1 -9617.0
PSMB11 -9770.0
PSMB6 -9876.0
LAMA1 -9879.0
RPL10L -10035.0
PSME1 -10185.0
ZSWIM8 -10314.0
NCSTN -10362.0
TUBA3D -11092.0
PSPN -11148.0


REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS

REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
1355
set REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS
setSize 299
pANOVA 0.0134
s.dist 0.0831
p.adjustANOVA 0.489



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
MYD88 10180
HDAC5 10058
PRKAR2A 10044
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
THEM4 9510
NR4A1 9496
FGF20 9459
PLCG1 9389
PSMD12 9352
PDGFRB 9216
AGO1 9204

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
MYD88 10180
HDAC5 10058
PRKAR2A 10044
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
THEM4 9510
NR4A1 9496
FGF20 9459
PLCG1 9389
PSMD12 9352
PDGFRB 9216
AGO1 9204
PRKACG 9090
PSMB10 8921
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
PSMD4 8409
ERBB2 8390
PSMC1 8362
SNAI2 8130
RAC1 8105
ATN1 8005
MTA3 7961
UBA52 7820
USP7 7653
AHCYL1 7545
AGO4 7383
PSMC6 7360
PSMB7 7322
PSMB1 7304
PSME2 7282
PSMB3 7246
PSMA1 7230
FGFR3 7187
FGF17 7101
CAMK2G 7003
FRK 6880
RRAGD 6794
PSMC5 6773
TRAF6 6579
PSMD1 6519
PIK3R2 6512
PIP4K2A 6410
PRKAR1A 6364
HDAC1 6190
RPS6KB2 6157
MAF1 6056
PHC1 5822
ATF2 5785
ERBB3 5779
PPP2CA 5736
SCMH1 5731
TRAT1 5711
NR2E1 5688
IL1RAP 5606
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF7 5358
HDAC7 5324
IER3 5279
PRR5 5200
UBB 5177
PSMA6 5154
FGF18 5144
CSNK2A1 5137
FOXO3 5124
PRKCE 5066
IL1RL1 5027
HDAC2 4994
PDE1A 4964
BMI1 4950
KLB 4842
PSMA3 4777
HDAC3 4748
GATAD2B 4713
PIK3AP1 4602
ADCY8 4577
SNAI1 4558
CAMK4 4542
PSMD13 4481
PSMD11 4322
KDM1A 4315
PSMA4 4297
FGF6 4287
CAMK2D 4280
NBEA 4110
PDGFRA 4105
FGF10 4019
AKT1S1 3978
PPARG 3905
PHLPP1 3904
FGF3 3835
JUN 3797
KL 3743
TNKS 3727
PSMC4 3690
PPP2R5B 3627
CDKN1A 3616
RBBP4 3586
PSMA7 3408
ADCY6 3330
CAMK2A 3300
PSMA8 3274
FRS2 3246
PRKACB 3156
MET 3117
FGFR1 2972
SUZ12 2965
PIK3R1 2800
LAMTOR3 2763
CDKN1B 2756
PRKCD 2716
PPP2R1A 2659
GAB2 2556
CBX4 2532
LAMTOR2 2473
GATAD2A 2417
ESR1 2393
RHOG 2306
ADCY7 2289
PSMB5 2174
GSK3A 2051
UBC 1879
CREB1 1764
EZH2 1739
RRAGC 1719
FGF1 1692
KPNA2 1445
SEM1 1440
AGO2 1431
MECOM 1408
PRKCG 1403
ADCY9 1402
PSMD3 1303
TNRC6B 1301
ITPR2 1206
TNKS2 1186
FGF23 1055
AGO3 977
FGFR2 929
ESR2 800
REST 787
PRKCA 759
PHLPP2 747
PSME3 614
PSMD6 518
CBX8 508
EGR1 485
KIT 446
CASP9 286
FGF8 199
PHC3 197
PSMD14 114
MDM2 76
GRK2 -131
PPP2R5E -323
AKT1 -370
RPS27A -409
CAMKK2 -410
NRG3 -470
PREX2 -472
STUB1 -563
PPP2R5C -775
RPTOR -890
PTEN -898
MAPKAP1 -919
ERBB4 -921
MTA1 -965
PPP2R5D -1030
VAV1 -1113
PSMD5 -1267
GSK3B -1274
PSMB4 -1390
PIP5K1B -1542
GAB1 -1551
PIP5K1C -1573
RCOR1 -1607
NRG1 -1678
NEDD4 -1689
MAPK1 -1793
NRG4 -1796
PPP2R5A -1835
IRS1 -2009
FGF2 -2057
PIK3R3 -2257
STRN -2298
BAD -2389
SRC -2605
FGF9 -2778
RNF146 -2810
ADCY3 -2818
LAMTOR5 -2866
PSMD7 -3011
RHEB -3154
CHD4 -3171
TP53 -3175
PSMB8 -3188
EGF -3230
NRG2 -3275
FOXO6 -3278
AKT3 -3379
MTA2 -3687
PHC2 -3689
PSMB9 -3719
CALM1 -3759
PDE1B -3769
CHD3 -3786
IL33 -3824
PSMD8 -3830
PML -3934
FYN -3958
CSNK2B -3971
TNRC6C -4307
CSNK2A2 -4372
CBX6 -4376
SLC38A9 -4430
CAMK2B -4518
CHUK -4542
TNRC6A -4567
PSMC3 -4708
PPP2R1B -4709
PIK3CB -4734
RRAGA -4743
INSR -4769
FLT3 -4780
USP13 -4878
TGFA -4899
ADCY2 -4906
PIP4K2C -4979
FOXO1 -5042
IRS2 -5058
EED -5263
MLST8 -5409
TSC2 -5491
AKT2 -5525
FGF19 -5544
PSMA5 -5619
ITPR3 -5674
RING1 -5693
ADCY5 -5782
PPP2CB -5808
PRKACA -5856
PDE1C -5879
ITPR1 -5910
PSME4 -6007
RICTOR -6117
PSMA2 -6134
CBX2 -6155
RNF2 -6179
INS -6246
MBD3 -6409
PSMC2 -6591
ADCY4 -6612
PRKAR2B -6640
EREG -6751
KITLG -6856
CAMKK1 -6893
MKRN1 -7018
MTOR -7026
PRKAR1B -7252
PSMF1 -7266
EGFR -7457
SALL4 -7500
MAPK3 -7507
PSMD9 -7539
LAMTOR4 -7556
LAMTOR1 -7679
MOV10 -7718
PSMB2 -7879
PDGFA -7896
PDPK1 -7938
IRAK4 -8264
PSMD2 -8354
OTUD3 -8438
FGFR4 -8535
PIP4K2B -8701
WWP2 -8917
ADCY1 -8921
TRIM27 -8971
TRIB3 -9353
PIP5K1A -9637
EPGN -9669
PSMB11 -9770
PSMB6 -9876
FGF22 -10022
PSME1 -10185
ICOS -10796


REACTOME_RHOT1_GTPASE_CYCLE

REACTOME_RHOT1_GTPASE_CYCLE
1384
set REACTOME_RHOT1_GTPASE_CYCLE
setSize 5
pANOVA 0.0137
s.dist 0.637
p.adjustANOVA 0.489



Top enriched genes

Top 20 genes
GeneID Gene Rank
RHOT1 8996
MYO19 8605
RAP1GDS1 6748
TRAK1 5220
TRAK2 4290

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RHOT1 8996
MYO19 8605
RAP1GDS1 6748
TRAK1 5220
TRAK2 4290


REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK
371
set REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK
setSize 111
pANOVA 0.0147
s.dist 0.134
p.adjustANOVA 0.505



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
MYD88 10180
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
THEM4 9510
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632
LCK 10443
CD28 10433
CD19 10365
AREG 10332
MYD88 10180
HBEGF 10041
CD86 9958
PDGFB 9767
BTC 9757
CD80 9595
THEM4 9510
FGF20 9459
PDGFRB 9216
PIK3CD 8742
FLT3LG 8737
HGF 8662
GRB2 8575
ERBB2 8390
RAC1 8105
FGFR3 7187
FGF17 7101
TRAF6 6579
PIK3R2 6512
PIP4K2A 6410
ERBB3 5779
PPP2CA 5736
TRAT1 5711
IL1RAP 5606
PIK3CA 5509
FGF5 5471
FGF4 5452
PTPN11 5384
FGF7 5358
IER3 5279
FGF18 5144
IL1RL1 5027
KLB 4842
PIK3AP1 4602
FGF6 4287
PDGFRA 4105
FGF10 4019
PHLPP1 3904
FGF3 3835
KL 3743
PPP2R5B 3627
FRS2 3246
MET 3117
FGFR1 2972
PIK3R1 2800
PPP2R1A 2659
GAB2 2556
ESR1 2393
RHOG 2306
FGF1 1692
FGF23 1055
FGFR2 929
ESR2 800
PHLPP2 747
KIT 446
FGF8 199
PPP2R5E -323
AKT1 -370
NRG3 -470
PPP2R5C -775
PTEN -898
ERBB4 -921
PPP2R5D -1030
VAV1 -1113
PIP5K1B -1542
GAB1 -1551
PIP5K1C -1573
NRG1 -1678
MAPK1 -1793
NRG4 -1796
PPP2R5A -1835
IRS1 -2009
FGF2 -2057
PIK3R3 -2257
STRN -2298
SRC -2605
FGF9 -2778
EGF -3230
NRG2 -3275
AKT3 -3379
IL33 -3824
FYN -3958
PPP2R1B -4709
PIK3CB -4734
INSR -4769
FLT3 -4780
TGFA -4899
PIP4K2C -4979
IRS2 -5058
AKT2 -5525
FGF19 -5544
PPP2CB -5808
INS -6246
EREG -6751
KITLG -6856
EGFR -7457
MAPK3 -7507
PDGFA -7896
IRAK4 -8264
FGFR4 -8535
PIP4K2B -8701
TRIB3 -9353
PIP5K1A -9637
EPGN -9669
FGF22 -10022
ICOS -10796


REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES

REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES
620
set REACTOME_ATF6_ATF6_ALPHA_ACTIVATES_CHAPERONES
setSize 11
pANOVA 0.0148
s.dist 0.425
p.adjustANOVA 0.505



Top enriched genes

Top 20 genes
GeneID Gene Rank
HSP90B1 9493
XBP1 8189
ATF4 7691
HSPA5 7438
CALR 7250
DDIT3 6149
MBTPS1 4826
NFYB 4719
NFYC 1279
ATF6 -3879
NFYA -4335

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
HSP90B1 9493
XBP1 8189
ATF4 7691
HSPA5 7438
CALR 7250
DDIT3 6149
MBTPS1 4826
NFYB 4719
NFYC 1279
ATF6 -3879
NFYA -4335


REACTOME_SARS_COV_1_HOST_INTERACTIONS

REACTOME_SARS_COV_1_HOST_INTERACTIONS
1550
set REACTOME_SARS_COV_1_HOST_INTERACTIONS
setSize 92
pANOVA 0.0153
s.dist 0.146
p.adjustANOVA 0.509



Top enriched genes

Top 20 genes
GeneID Gene Rank
SFN 10541
RPS5 9848
IRAK2 9811
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
PYCARD 9188
RPS25 8911
RPS18 8674
BCL2L1 8672
RPS2 8671
YWHAH 8448
RCAN3 8238
RPSA 8200
RPS15 8112
RPS6 7877
UBA52 7820
RPS19 7794
YWHAZ 7793

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
SFN 10541
RPS5 9848
IRAK2 9811
RPS8 9668
RPS12 9566
RPS3 9408
RPS7 9253
PYCARD 9188
RPS25 8911
RPS18 8674
BCL2L1 8672
RPS2 8671
YWHAH 8448
RCAN3 8238
RPSA 8200
RPS15 8112
RPS6 7877
UBA52 7820
RPS19 7794
YWHAZ 7793
PSMC6 7360
RPS3A 7064
CAV1 6906
ITCH 6780
TRAF6 6579
PKLR 6558
HNRNPA1 5832
RPS24 5215
UBB 5177
RIPK3 4916
RPS10 4677
RPS15A 4661
TRAF3 4587
PPIH 4561
NPM1 4266
PPIA 4220
NFKBIA 4178
RPS28 3491
RPS14 3317
YWHAG 3022
PCBP2 2413
SFTPD 2282
RPS21 2267
TKFC 1939
UBC 1879
TOMM70 1600
IKBKE 1539
SMAD3 1511
EEF1A1 1448
KPNA2 1445
FKBP1A 1316
SERPINE1 1090
SP1 444
FAU 437
YWHAQ -284
TBK1 -310
RPS16 -365
RPS27A -409
NLRP3 -608
PPIG -1400
YWHAB -1452
NFKB1 -1676
RPS13 -1714
MAVS -2423
RPS11 -2454
NMI -2482
RPS9 -2591
RIGI -2665
RUNX1 -2900
SIKE1 -2962
RPS27L -3101
TRIM25 -3199
CASP1 -3763
RPS23 -3882
PALS1 -4069
IRF3 -4702
UBE2I -5025
IFIH1 -5614
EP300 -5781
PPIB -6178
RPS27 -6223
KPNB1 -6962
SMAD4 -7376
PDPK1 -7938
RPS20 -8058
RPS29 -8230
RELA -8902
YWHAE -9062
RPS26 -9575
RIPK1 -9673
BST2 -10372
STING1 -10916


REACTOME_RHO_GTPASE_CYCLE

REACTOME_RHO_GTPASE_CYCLE
1368
set REACTOME_RHO_GTPASE_CYCLE
setSize 423
pANOVA 0.0157
s.dist 0.0685
p.adjustANOVA 0.509



Top enriched genes

Top 20 genes
GeneID Gene Rank
RAC2 10632
POTEE 10526
ARHGAP11B 10519
LCK 10443
IL32 10423
ARHGAP11A 10350
SWAP70 10213
RAC3 10112
ARAP3 10001
RHOV 9764
NCF2 9704
SH3BP1 9696
ARHGAP18 9609
ARHGEF25 9457
LETM1 9322
CAVIN1 9309
ARHGAP9 9244
PLXND1 9058
FMNL3 8892
ARHGDIG 8869

Click HERE to show all gene set members

All member genes
GeneID Gene Rank
RAC2 10632.0
POTEE 10526.0
ARHGAP11B 10519.0
LCK 10443.0
IL32 10423.0
ARHGAP11A 10350.0
SWAP70 10213.0
RAC3 10112.0
ARAP3 10001.0
RHOV 9764.0
NCF2 9704.0
SH3BP1 9696.0
ARHGAP18 9609.0
ARHGEF25 9457.0
LETM1 9322.0
CAVIN1 9309.0
ARHGAP9 9244.0
PLXND1 9058.0
FMNL3 8892.0
ARHGDIG 8869.0
ARHGEF40 8852.0
RTKN 8836.0
ARHGAP45 8812.0
ARHGAP27 8811.0
MTX1 8695.0
TPM3 8612.0
GRB2 8575.0
ACTN1 8393.0
SLITRK5 8294.0
FILIP1 8263.0
ABI1 8259.0
TOR1AIP1 8234.0
GRB7 8233.0
FNBP1L 8173.0
NOXA1 8167.0
RAC1 8105.0
RAB7A 8086.0
ARHGDIA 8024.0
DDX39B 8017.0
HNRNPC 7870.0
YKT6 7866.0
CDC42EP3 7842.0
FNBP1 7834.0
TMEM59 7774.0
ARHGEF11 7717.0
CKB 7593.0
CSK 7572.0
CCT7 7564.0
PLXNB1 7554.0
HSP90AB1 7509.0
DOCK10 7487.0
ARHGAP30 7470.0
RHOBTB2 7469.0
BASP1 7450.0
GNA13 7388.0
PRAG1 7274.0
RHOF 7262.0
LMNB1 7218.0
RHOH 7213.0
COPS4 7144.0
ARHGEF2 7099.0
HINT2 7023.0
TNFAIP1 7012.0
MYO6 6926.0
CAV1 6906.0
ARHGDIB 6895.0
STAM2 6841.0
PKN1 6806.0
UBXN11 6778.0
DSG2 6719.0
SEMA4F 6678.0
PIK3R2 6512.0
ADD3 6430.0
FAM13A 6412.0
ARHGAP25 6323.0
CHN1 6243.0
SOS2 6167.0
ALS2 6136.0
STIP1 5909.0
AAAS 5874.0
SNAP23 5828.0
SYDE2 5783.0
ARHGEF17 5739.0
RND2 5701.0
SCFD1 5654.0
PIK3CA 5509.0
NET1 5479.0
PREX1 5472.0
STMN2 5466.0
RHOB 5437.0
PLEKHG3 5414.0
ARHGAP32 5408.0
HMOX2 5372.0
CCP110 5339.0
SH3PXD2A 5312.0
RHOJ 5280.0
TXNL1 5240.0
GFOD1 5145.0
VANGL1 5134.0
WIPF1 5120.0
RASGRF2 5082.0
EPHA2 5061.0
DOCK3 4980.0
PAK6 4955.0
DEF6 4846.0
TJP2 4831.0
PEAK1 4781.0
CFTR 4780.0
PTK2B 4776.0
TMPO 4717.0
SLK 4705.0
MPP7 4604.0
NOX3 4581.0
KIF14 4535.0
ACBD5 4409.0
PARD6A 4299.5
ARHGEF19 4255.0
ITSN1 4250.0
PLD1 4239.0
FERMT2 4234.0
ARHGEF3 4197.0
DIAPH1 4167.0
WASF1 4067.0
EFHD2 4025.0
SAMM50 3995.0
CDC42EP2 3989.0
CDC42EP1 3909.0
CCDC115 3858.0
ITSN2 3731.0
DSP 3699.0
ARHGAP1 3687.0
FLOT1 3675.0
PLEKHG1 3668.0
WDR91 3645.0
ARFGAP3 3632.0
TMOD3 3606.0
CCDC88A 3563.0
LRRC1 3522.0
NCKAP1L 3509.0
PICALM 3506.0
NGEF 3504.0
ARHGAP42 3496.0
DOCK7 3489.0
ERBIN 3417.0
BAIAP2 3397.0
SYDE1 3356.0
FMNL1 3328.0
FRS2 3246.0
FAM91A1 3224.0
WDR6 3162.0
DNMBP 3145.0
SHMT2 3060.0
RALGAPA1 3058.0
TIAM2 3012.0
NDUFA5 2958.0
CDC42EP4 2868.0
KTN1 2863.0
FAF2 2839.0
RAPGEF1 2834.0
ESYT1 2814.0
PIK3R1 2800.0
RHOU 2790.0
ARHGAP17 2777.0
JAG1 2647.0
TIAM1 2621.0
DST 2595.0
IQGAP3 2586.0
SPTBN1 2557.0
WASL 2548.0
ARHGEF7 2547.0
DLC1 2485.0
ARAP1 2469.0
RHOG 2306.0
ABCD3 2299.0
FAM135A 2260.0
ACTG1 2257.0
ACTC1 2208.0
LEMD3 2116.0
SHKBP1 2090.0
WHAMM 2088.0
RRAS2 2055.0
WASF2 1967.0
FRS3 1906.0
COPS2 1905.0
MSI2 1856.0
VAV2 1829.0
ARHGEF28 1808.0
ARL13B 1697.0
TWF1 1694.0
ARHGEF26 1684.0
FLOT2 1683.0
ARHGAP29 1680.0
RBBP6 1630.0
OBSCN 1580.0
ABL2 1575.0
FGD2 1564.0
DBN1 1562.0
MYO9B 1546.0
PLEKHG2 1459.0
DOCK5 1432.0
STARD13 1399.0
NCKAP1 1336.0
GJA1 1310.0
TRIO 1294.0
CDC42EP5 1256.0
FMNL2 1235.0
ABI2 1171.0
SPATA13 1140.0
DOCK2 1089.0
BCR 1013.0
ZAP70 921.0
CYFIP2 869.0
ALDH3A2 868.0
ARHGAP39 735.0
FAM169A 715.0
VAPB 706.0
RHPN1 669.0
ARHGAP33 654.0
KIDINS220 625.0
HSP90AA1 550.0
ACTB 524.0
DOCK4 523.0
MACO1 486.0
ARHGEF10 461.0
ELMO2 411.0
FAM13B 407.0
BRK1 401.0
ARAP2 367.0
RND1 353.0
SRGAP3 237.0
ARHGAP5 219.0
CCT6A 68.0
TEX2 41.0
SENP1 18.0
NCK2 3.0
ROCK1 -29.0
DLG5 -44.0
NIPSNAP2 -116.0
ARHGEF12 -136.0
TRA2B -167.0
GMIP -218.0
ARHGAP10 -221.0
CLTC -436.0
VAV3 -453.0
PREX2 -472.0
BAIAP2L2 -522.0
SLITRK3 -537.0
UACA -568.0
DAAM1 -762.0
DEPDC1B -801.0
ARHGAP20 -896.0
RACGAP1 -903.0
ARHGAP19 -957.0
IQGAP2 -984.0
LMAN1 -992.0
SRGAP1 -1059.0
CPNE8 -1089.0
VAV1 -1113.0
NOXO1 -1172.0
RNF20 -1254.0
KCTD13 -1328.0
DSG1 -1384.0
PARD6B -1433.0
GARRE1 -1458.0
ANLN -1519.0
PAK4 -1568.0
RHOBTB1 -1572.0
CHN2 -1655.0
GOPC -1663.0
ARHGEF39 -1711.0
RASAL2 -1715.0
KALRN -1722.0
CYBA -1747.0
MYO9A -1758.0
TAGAP -1803.0
HSPE1 -1836.0
CDC42BPA -1863.0
ARHGAP22 -1896.0
PHIP -1932.0
ARHGAP26 -1961.0
PKN2 -1996.0
AKAP12 -2021.0
FGD3 -2135.0
RND3 -2157.0
ARHGAP21 -2187.0
FGD5 -2190.0
PKP4 -2205.0
AMIGO2 -2250.0
PIK3R3 -2257.0
WDR81 -2262.0
RHOQ -2264.0
ARHGAP31 -2277.0
SLC4A7 -2336.0
DIAPH3 -2399.0
SCRIB -2484.0
PGRMC2 -2504.0
RHOA -2508.0
PCDH7 -2534.0
SRC -2605.0
PTPN13 -2609.0
DOCK1 -2692.0
MUC13 -2747.0
PLEKHG5 -2781.0
DDX4 -2884.0
AKAP13 -2912.0
CDC42BPB -3071.0
SH3RF1 -3091.0
PAK5 -3141.0
EMC3 -3238.0
JUP -3332.0
ARHGAP44 -3334.0
FGD4 -3415.0
DOCK9 -3422.0
RALBP1 -3432.0
GIT2 -3534.0
TAOK3 -3699.0
ARHGAP24 -3796.0
WASF3 -3812.0
TMEM87A -3919.0
ANKFY1 -3942.0
ARHGAP35 -3993.0
PLEKHG6 -4133.0
PAK1 -4397.0
CUL3 -4504.0
MCAM -4515.0
FARP1 -4598.0
MTR -4602.0
RHOD -4635.0
ARHGAP12 -4639.0
SOWAHC -4675.0
MAP3K11 -4697.0
VRK2 -4707.0
SPEN -4742.0
NCK1 -4796.0
ANKRD26 -4805.0
SLC1A5 -4965.0
SRGAP2 -4972.0
FAM83B -5061.0
IQGAP1 -5081.0
CAPZB -5120.0
BLTP3B -5197.0
STK10 -5224.0
PDE5A -5357.0
STBD1 -5363.0
PLEKHG4 -5444.0
ROCK2 -5476.0
DBT -5479.0
WIPF3 -5508.0
CEP97 -5561.0
SRRM1 -5563.0
GOLGA3 -5584.0
TFRC -5590.0
ECT2 -5607.0
NUDC -5722.0
CCT2 -5727.0
ARHGAP23 -5775.0
ARHGEF4 -5793.0
CDC42 -5795.0
RHOC -5842.0
SOS1 -5894.0
CIT -6249.0
NSFL1C -6419.0
PLXNA1 -6420.0
LBR -6424.0
ABR -6462.0
KCTD3 -6518.0
SPTAN1 -6849.0
CPD -6914.0
BAIAP2L1 -6923.0
WDR11 -7009.0
CKAP4 -7014.0
ARHGAP15 -7030.0
TPM4 -7113.0
WIPF2 -7148.0
CDC42SE2 -7153.0
CPSF7 -7176.0
PLEKHG4B -7215.0
STK38 -7274.0
ARHGEF16 -7307.0
DDRGK1 -7338.0
ARHGEF18 -7348.0
TUBA1B -7437.0
ARHGAP28 -7584.0
LAMTOR1 -7679.0
NDUFS3 -7717.0
TRIP10 -7928.0
STX5 -7940.0
ANKLE2 -8011.0
DOCK8 -8027.0
ARHGEF10L -8035.0
STOM -8047.0
ARFGAP2 -8247.0
CDC37 -8277.0
STEAP3 -8292.0
DOCK6 -8345.0
PKN3 -8387.0
VIM -8420.0
FARP2 -8482.0
STAM -8576.0
RHPN2 -8591.0
EPSTI1 -8603.0
VAMP3 -8620.0
ARHGAP8 -8720.0
C1QBP -8727.0
ITGB1 -8750.0
CYFIP1 -8773.0
OSBPL11 -8816.0
ARHGAP40 -8884.0
HGS -8903.0
PAK2 -8910.0
NCF4 -8914.0
WWP2 -8917.0
PLD2 -8962.0
GPS1 -9023.0
MCF2L -9261.0
NISCH -9376.0
ARHGEF1 -9384.0
GIT1 -9617.0
ZNF512B -9654.0
ARHGEF15 -10134.0
VANGL2 -10171.0
ARHGEF5 -10285.0
VCP -10379.0


Here is the session info with all the versions of packages used.

sessionInfo()
## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report