Mitch Report

date generated: 2024-01-18

Background

Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch

Input profiles

Here is the first few lines of the input profile.

The profiling data being passed to mitch

	x
A1BG	0.0002896
A1BG-AS1	0.0007706
A1CF	0.0059819
A2M	0.0014745
A2M-AS1	-0.0142040
A2ML1	0.0022877

Here are some metrics about the input data profile:

Profiling data metrics

	Profile metrics
num_genesets	1654
num_genes_in_profile	22007
duplicated_genes_present	0
num_profile_genes_in_sets	10383
num_profile_genes_not_in_sets	11624

Here is a plot of the input profiles. Note the dynamic ranges.

Here is the contour plot of the profile including all detected genes.

Input genesets

Here are some metrics about the gene sets used:

GMT file of genesets: c2.cp.reactome.v2023.1.Hs.symbols.gmt

Gene set metrics

	Gene sets metrics
num_genesets	1654
num_genesets_excluded	365
num_genesets_included	1289

Differential pathway expression

Interactive enrichment scatterplot

Significance is calculated by -log10(p-value). All points shown are FDR<0.05.

Significance is calculated by -log10(p-value). Top N sets shown irrespective of FDR.

Results table

Top N= 50 gene sets

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set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	1.00e-18	0.2750	1.65e-15
REACTOME SENSORY PERCEPTION	555	4.69e-12	0.1720	3.85e-09
REACTOME KERATINIZATION	210	1.39e-08	0.2270	7.60e-06
REACTOME NEUTROPHIL DEGRANULATION	460	1.39e-06	-0.1310	5.71e-04
REACTOME METABOLISM OF LIPIDS	709	4.41e-06	-0.1010	1.45e-03
REACTOME INNATE IMMUNE SYSTEM	1002	1.76e-05	-0.0801	4.82e-03
REACTOME CHROMATIN MODIFYING ENZYMES	252	4.12e-05	-0.1500	9.66e-03
REACTOME ASPIRIN ADME	42	8.22e-05	0.3510	1.69e-02
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	1.25e-04	0.4050	2.27e-02
REACTOME RHOC GTPASE CYCLE	71	3.60e-04	-0.2450	5.76e-02
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	3.90e-04	-0.0798	5.76e-02
REACTOME PHOSPHOLIPID METABOLISM	201	4.39e-04	-0.1440	5.76e-02
REACTOME RHOB GTPASE CYCLE	67	4.56e-04	-0.2480	5.76e-02
REACTOME XENOBIOTICS	22	6.64e-04	0.4190	7.78e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	8.17e-04	0.5170	8.92e-02
REACTOME RHOA GTPASE CYCLE	142	8.69e-04	-0.1620	8.92e-02
REACTOME MEMBRANE TRAFFICKING	603	1.22e-03	-0.0771	1.06e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	1.27e-03	-0.2370	1.06e-01
REACTOME TCR SIGNALING	113	1.28e-03	0.1750	1.06e-01
REACTOME SIGNALING BY VEGF	102	1.29e-03	-0.1840	1.06e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.43e-03	0.1650	1.10e-01
REACTOME RHO GTPASE CYCLE	423	1.47e-03	-0.0901	1.10e-01
REACTOME DRUG ADME	103	2.02e-03	0.1760	1.44e-01
REACTOME LEISHMANIA INFECTION	156	2.40e-03	-0.1410	1.56e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	2.45e-03	-0.4120	1.56e-01
REACTOME TBC RABGAPS	40	2.56e-03	-0.2760	1.56e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	2.63e-03	-0.7090	1.56e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	2.66e-03	-0.1910	1.56e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	2.75e-03	-0.6540	1.56e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	2.96e-03	0.0527	1.62e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	3.16e-03	-0.2460	1.63e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	3.17e-03	-0.0682	1.63e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	3.41e-03	-0.2330	1.64e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	3.50e-03	-0.1610	1.64e-01
REACTOME RAC2 GTPASE CYCLE	81	3.73e-03	-0.1860	1.64e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	3.79e-03	-0.0469	1.64e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	3.80e-03	-0.2110	1.64e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	4.00e-03	-0.0968	1.64e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	4.03e-03	0.6280	1.64e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	4.09e-03	0.5860	1.64e-01
REACTOME SYNTHESIS OF PG	8	4.10e-03	-0.5860	1.64e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	4.51e-03	-0.2560	1.74e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	4.55e-03	0.2990	1.74e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	5.17e-03	-0.2660	1.93e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	5.65e-03	0.2020	2.06e-01
REACTOME BIOLOGICAL OXIDATIONS	210	5.96e-03	0.1100	2.08e-01
REACTOME ATORVASTATIN ADME	9	5.96e-03	0.5290	2.08e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	6.68e-03	-0.4190	2.27e-01
REACTOME PD 1 SIGNALING	21	6.76e-03	0.3410	2.27e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	7.11e-03	-0.5870	2.29e-01

---

Results (complete table)

Click HERE to show results for all gene sets

Complete results

set	setSize	pANOVA	s.dist	p.adjustANOVA
REACTOME OLFACTORY SIGNALING PATHWAY	348	1.00e-18	0.275000	1.65e-15
REACTOME SENSORY PERCEPTION	555	4.69e-12	0.172000	3.85e-09
REACTOME KERATINIZATION	210	1.39e-08	0.227000	7.60e-06
REACTOME NEUTROPHIL DEGRANULATION	460	1.39e-06	-0.131000	5.71e-04
REACTOME METABOLISM OF LIPIDS	709	4.41e-06	-0.101000	1.45e-03
REACTOME INNATE IMMUNE SYSTEM	1002	1.76e-05	-0.080100	4.82e-03
REACTOME CHROMATIN MODIFYING ENZYMES	252	4.12e-05	-0.150000	9.66e-03
REACTOME ASPIRIN ADME	42	8.22e-05	0.351000	1.69e-02
REACTOME GENERATION OF SECOND MESSENGER MOLECULES	30	1.25e-04	0.405000	2.27e-02
REACTOME RHOC GTPASE CYCLE	71	3.60e-04	-0.245000	5.76e-02
REACTOME SIGNALING BY RHO GTPASES MIRO GTPASES AND RHOBTB3	679	3.90e-04	-0.079800	5.76e-02
REACTOME PHOSPHOLIPID METABOLISM	201	4.39e-04	-0.144000	5.76e-02
REACTOME RHOB GTPASE CYCLE	67	4.56e-04	-0.248000	5.76e-02
REACTOME XENOBIOTICS	22	6.64e-04	0.419000	7.78e-02
REACTOME CREATION OF C4 AND C2 ACTIVATORS	14	8.17e-04	0.517000	8.92e-02
REACTOME RHOA GTPASE CYCLE	142	8.69e-04	-0.162000	8.92e-02
REACTOME MEMBRANE TRAFFICKING	603	1.22e-03	-0.077100	1.06e-01
REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	62	1.27e-03	-0.237000	1.06e-01
REACTOME TCR SIGNALING	113	1.28e-03	0.175000	1.06e-01
REACTOME SIGNALING BY VEGF	102	1.29e-03	-0.184000	1.06e-01
REACTOME FORMATION OF THE CORNIFIED ENVELOPE	125	1.43e-03	0.165000	1.10e-01
REACTOME RHO GTPASE CYCLE	423	1.47e-03	-0.090100	1.10e-01
REACTOME DRUG ADME	103	2.02e-03	0.176000	1.44e-01
REACTOME LEISHMANIA INFECTION	156	2.40e-03	-0.141000	1.56e-01
REACTOME PRE NOTCH PROCESSING IN GOLGI	18	2.45e-03	-0.412000	1.56e-01
REACTOME TBC RABGAPS	40	2.56e-03	-0.276000	1.56e-01
REACTOME ESTROGEN STIMULATED SIGNALING THROUGH PRKCZ	6	2.63e-03	-0.709000	1.56e-01
REACTOME FCGAMMA RECEPTOR FCGR DEPENDENT PHAGOCYTOSIS	83	2.66e-03	-0.191000	1.56e-01
REACTOME LINOLEIC ACID LA METABOLISM	7	2.75e-03	-0.654000	1.56e-01
REACTOME DEVELOPMENTAL BIOLOGY	1115	2.96e-03	0.052700	1.62e-01
REACTOME IRE1ALPHA ACTIVATES CHAPERONES	48	3.16e-03	-0.246000	1.63e-01
REACTOME VESICLE MEDIATED TRANSPORT	642	3.17e-03	-0.068200	1.63e-01
REACTOME REGULATION OF CHOLESTEROL BIOSYNTHESIS BY SREBP SREBF	53	3.41e-03	-0.233000	1.64e-01
REACTOME RAB REGULATION OF TRAFFICKING	110	3.50e-03	-0.161000	1.64e-01
REACTOME RAC2 GTPASE CYCLE	81	3.73e-03	-0.186000	1.64e-01
REACTOME POST TRANSLATIONAL PROTEIN MODIFICATION	1356	3.79e-03	-0.046900	1.64e-01
REACTOME SIGNALING BY BRAF AND RAF1 FUSIONS	63	3.80e-03	-0.211000	1.64e-01
REACTOME ASPARAGINE N LINKED GLYCOSYLATION	299	4.00e-03	-0.096800	1.64e-01
REACTOME INTERLEUKIN 36 PATHWAY	7	4.03e-03	0.628000	1.64e-01
REACTOME SYNTHESIS OF EPOXY EET AND DIHYDROXYEICOSATRIENOIC ACIDS DHET	8	4.09e-03	0.586000	1.64e-01
REACTOME SYNTHESIS OF PG	8	4.10e-03	-0.586000	1.64e-01
REACTOME ACTIVATION OF GENE EXPRESSION BY SREBF SREBP	41	4.51e-03	-0.256000	1.74e-01
REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	30	4.55e-03	0.299000	1.74e-01
REACTOME RUNX1 INTERACTS WITH CO FACTORS WHOSE PRECISE EFFECT ON RUNX1 TARGETS IS NOT KNOWN	37	5.17e-03	-0.266000	1.93e-01
REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	63	5.65e-03	0.202000	2.06e-01
REACTOME BIOLOGICAL OXIDATIONS	210	5.96e-03	0.110000	2.08e-01
REACTOME ATORVASTATIN ADME	9	5.96e-03	0.529000	2.08e-01
REACTOME PTK6 REGULATES RHO GTPASES RAS GTPASE AND MAP KINASES	14	6.68e-03	-0.419000	2.27e-01
REACTOME PD 1 SIGNALING	21	6.76e-03	0.341000	2.27e-01
REACTOME NFE2L2 REGULATES PENTOSE PHOSPHATE PATHWAY GENES	7	7.11e-03	-0.587000	2.29e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR4	14	7.14e-03	0.415000	2.29e-01
REACTOME PLATELET CALCIUM HOMEOSTASIS	27	7.26e-03	-0.298000	2.29e-01
REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	123	7.62e-03	-0.139000	2.32e-01
REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	76	7.63e-03	-0.177000	2.32e-01
REACTOME PHASE I FUNCTIONALIZATION OF COMPOUNDS	101	9.18e-03	0.150000	2.74e-01
REACTOME ORGANELLE BIOGENESIS AND MAINTENANCE	277	9.49e-03	-0.090600	2.78e-01
REACTOME SENSORY PERCEPTION OF SALTY TASTE	6	9.70e-03	-0.610000	2.79e-01
REACTOME EUKARYOTIC TRANSLATION INITIATION	110	1.01e-02	0.142000	2.80e-01
REACTOME MRNA EDITING C TO U CONVERSION	8	1.01e-02	0.525000	2.80e-01
REACTOME RSK ACTIVATION	5	1.03e-02	-0.662000	2.80e-01
REACTOME FLT3 SIGNALING BY CBL MUTANTS	7	1.04e-02	0.559000	2.80e-01
REACTOME FATTY ACID METABOLISM	170	1.12e-02	-0.113000	2.93e-01
REACTOME RAC1 GTPASE CYCLE	172	1.12e-02	-0.112000	2.93e-01
REACTOME CELL CYCLE	666	1.21e-02	-0.057000	3.05e-01
REACTOME CYP2E1 REACTIONS	10	1.22e-02	0.458000	3.05e-01
REACTOME GLUCURONIDATION	23	1.23e-02	0.302000	3.05e-01
REACTOME VEGFR2 MEDIATED VASCULAR PERMEABILITY	26	1.26e-02	-0.283000	3.09e-01
REACTOME EUKARYOTIC TRANSLATION ELONGATION	87	1.28e-02	0.154000	3.09e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ACETYLATION	29	1.30e-02	-0.267000	3.09e-01
REACTOME TRIF MEDIATED PROGRAMMED CELL DEATH	9	1.33e-02	-0.477000	3.09e-01
REACTOME HISTIDINE CATABOLISM	8	1.34e-02	-0.505000	3.09e-01
REACTOME CHOLINE CATABOLISM	6	1.36e-02	0.582000	3.10e-01
REACTOME VEGFR2 MEDIATED CELL PROLIFERATION	19	1.43e-02	-0.324000	3.20e-01
REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	73	1.44e-02	0.166000	3.20e-01
REACTOME CASPASE ACTIVATION VIA EXTRINSIC APOPTOTIC SIGNALLING PATHWAY	25	1.50e-02	-0.281000	3.20e-01
REACTOME RAC3 GTPASE CYCLE	85	1.51e-02	-0.152000	3.20e-01
REACTOME ONCOGENIC MAPK SIGNALING	79	1.54e-02	-0.158000	3.20e-01
REACTOME PREVENTION OF PHAGOSOMAL LYSOSOMAL FUSION	9	1.55e-02	0.466000	3.20e-01
REACTOME REGULATION OF EXPRESSION OF SLITS AND ROBOS	161	1.56e-02	0.110000	3.20e-01
REACTOME REGULATION OF HMOX1 EXPRESSION AND ACTIVITY	5	1.58e-02	-0.623000	3.20e-01
REACTOME RHO GTPASE EFFECTORS	305	1.59e-02	-0.080300	3.20e-01
REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	37	1.61e-02	0.229000	3.20e-01
REACTOME RECYCLING OF EIF2 GDP	7	1.62e-02	0.525000	3.20e-01
REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	105	1.66e-02	0.135000	3.20e-01
REACTOME METABOLISM OF CARBOHYDRATES	279	1.67e-02	-0.083300	3.20e-01
REACTOME SPHINGOLIPID METABOLISM	84	1.67e-02	-0.151000	3.20e-01
REACTOME TRANSCRIPTIONAL ACTIVATION OF MITOCHONDRIAL BIOGENESIS	52	1.73e-02	-0.191000	3.27e-01
REACTOME AUF1 HNRNP D0 BINDS AND DESTABILIZES MRNA	54	1.78e-02	0.186000	3.32e-01
REACTOME PI METABOLISM	79	1.81e-02	-0.154000	3.32e-01
REACTOME RHOG GTPASE CYCLE	71	1.82e-02	-0.162000	3.32e-01
REACTOME SYNTHESIS OF DOLICHYL PHOSPHATE	6	1.85e-02	-0.555000	3.34e-01
REACTOME G PROTEIN BETA GAMMA SIGNALLING	30	1.88e-02	-0.248000	3.34e-01
REACTOME MYOCLONIC EPILEPSY OF LAFORA	9	1.89e-02	0.452000	3.34e-01
REACTOME GLYCOSPHINGOLIPID METABOLISM	39	1.92e-02	-0.217000	3.35e-01
REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	16	1.96e-02	-0.337000	3.39e-01
REACTOME MAPK6 MAPK4 SIGNALING	91	2.00e-02	0.141000	3.40e-01
REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	24	2.01e-02	0.274000	3.40e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH NMDA RECEPTOR MEDIATED ACTIVATION OF RAS SIGNALING	25	2.09e-02	-0.267000	3.46e-01
REACTOME SIGNALING BY MODERATE KINASE ACTIVITY BRAF MUTANTS	43	2.15e-02	-0.203000	3.46e-01
REACTOME KERATAN SULFATE KERATIN METABOLISM	34	2.17e-02	-0.227000	3.46e-01
REACTOME TRANSLATION	278	2.17e-02	0.080000	3.46e-01
REACTOME SARS COV 2 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	12	2.20e-02	-0.382000	3.46e-01
REACTOME MODULATION BY MTB OF HOST IMMUNE SYSTEM	6	2.22e-02	0.539000	3.46e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH ASSOCIATION WITH CO FACTORS	14	2.24e-02	-0.353000	3.46e-01
REACTOME DEGRADATION OF GLI1 BY THE PROTEASOME	59	2.26e-02	0.172000	3.46e-01
REACTOME LECTIN PATHWAY OF COMPLEMENT ACTIVATION	8	2.28e-02	0.465000	3.46e-01
REACTOME TRIGLYCERIDE CATABOLISM	23	2.28e-02	0.274000	3.46e-01
REACTOME RESPONSE OF EIF2AK4 GCN2 TO AMINO ACID DEFICIENCY	94	2.29e-02	0.136000	3.46e-01
REACTOME MITOCHONDRIAL BIOGENESIS	87	2.30e-02	-0.141000	3.46e-01
REACTOME RORA ACTIVATES GENE EXPRESSION	17	2.35e-02	-0.317000	3.48e-01
REACTOME ANTI INFLAMMATORY RESPONSE FAVOURING LEISHMANIA PARASITE INFECTION	74	2.35e-02	-0.152000	3.48e-01
REACTOME MAPK1 ERK2 ACTIVATION	9	2.38e-02	-0.435000	3.48e-01
REACTOME ROLE OF PHOSPHOLIPIDS IN PHAGOCYTOSIS	24	2.45e-02	-0.265000	3.56e-01
REACTOME KERATAN SULFATE BIOSYNTHESIS	28	2.51e-02	-0.245000	3.61e-01
REACTOME APC C MEDIATED DEGRADATION OF CELL CYCLE PROTEINS	87	2.61e-02	0.138000	3.72e-01
REACTOME FLT3 SIGNALING THROUGH SRC FAMILY KINASES	6	2.63e-02	0.524000	3.72e-01
REACTOME CELL CYCLE MITOTIC	539	2.66e-02	-0.055800	3.72e-01
REACTOME RHOQ GTPASE CYCLE	57	2.67e-02	-0.170000	3.72e-01
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	11	2.73e-02	-0.384000	3.76e-01
REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	26	2.84e-02	0.248000	3.89e-01
REACTOME ACTIVATION OF BAD AND TRANSLOCATION TO MITOCHONDRIA	15	2.89e-02	-0.326000	3.93e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSYLATION PRECURSOR BIOSYNTHESIS	15	2.96e-02	-0.324000	3.97e-01
REACTOME SIGNALING BY ROBO RECEPTORS	206	2.97e-02	0.087900	3.97e-01
REACTOME CDC42 GTPASE CYCLE	144	3.05e-02	-0.104000	4.04e-01
REACTOME DNA REPAIR	321	3.11e-02	-0.070000	4.05e-01
REACTOME SIGNAL TRANSDUCTION BY L1	20	3.12e-02	-0.278000	4.05e-01
REACTOME RAF ACTIVATION	33	3.13e-02	-0.217000	4.05e-01
REACTOME CIRCADIAN CLOCK	68	3.19e-02	-0.150000	4.09e-01
REACTOME CREB PHOSPHORYLATION	6	3.36e-02	-0.501000	4.27e-01
REACTOME LYSOSOME VESICLE BIOGENESIS	33	3.44e-02	-0.213000	4.31e-01
REACTOME RUNX3 REGULATES WNT SIGNALING	8	3.44e-02	0.432000	4.31e-01
REACTOME STING MEDIATED INDUCTION OF HOST IMMUNE RESPONSES	16	3.50e-02	-0.305000	4.35e-01
REACTOME SELENOAMINO ACID METABOLISM	108	3.56e-02	0.117000	4.40e-01
REACTOME ESR MEDIATED SIGNALING	210	3.68e-02	-0.083600	4.49e-01
REACTOME NEGATIVE FEEDBACK REGULATION OF MAPK PATHWAY	6	3.70e-02	-0.492000	4.49e-01
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	32	3.72e-02	-0.213000	4.49e-01
REACTOME PARASITE INFECTION	57	3.76e-02	-0.159000	4.51e-01
REACTOME TRANSCRIPTIONAL REGULATION BY TP53	351	3.91e-02	-0.064100	4.65e-01
REACTOME REGULATION OF PTEN GENE TRANSCRIPTION	59	3.95e-02	-0.155000	4.67e-01
REACTOME SUPPRESSION OF APOPTOSIS	7	4.00e-02	-0.448000	4.70e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	36	4.10e-02	-0.197000	4.72e-01
REACTOME ACTIVATION OF RAC1 DOWNSTREAM OF NMDARS	7	4.11e-02	-0.446000	4.72e-01
REACTOME POTASSIUM CHANNELS	102	4.13e-02	0.117000	4.72e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	25	4.15e-02	-0.236000	4.72e-01
REACTOME RHO GTPASES ACTIVATE WASPS AND WAVES	34	4.16e-02	-0.202000	4.72e-01
REACTOME ACTIVATION OF C3 AND C5	6	4.31e-02	-0.477000	4.73e-01
REACTOME COBALAMIN CBL VITAMIN B12 TRANSPORT AND METABOLISM	21	4.33e-02	-0.255000	4.73e-01
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK	17	4.35e-02	-0.283000	4.73e-01
REACTOME PI 3K CASCADE FGFR4	19	4.37e-02	0.267000	4.73e-01
REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	78	4.37e-02	-0.132000	4.73e-01
REACTOME G PROTEIN MEDIATED EVENTS	53	4.39e-02	-0.160000	4.73e-01
REACTOME COPII MEDIATED VESICLE TRANSPORT	66	4.40e-02	-0.143000	4.73e-01
REACTOME TRANSLESION SYNTHESIS BY POLK	17	4.41e-02	0.282000	4.73e-01
REACTOME SYNTHESIS OF 16 20 HYDROXYEICOSATETRAENOIC ACIDS HETE	9	4.48e-02	0.386000	4.73e-01
REACTOME DEFECTIVE F9 ACTIVATION	5	4.48e-02	0.518000	4.73e-01
REACTOME STABILIZATION OF P53	56	4.50e-02	0.155000	4.73e-01
REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	11	4.62e-02	0.347000	4.83e-01
REACTOME SIGNALING BY ACTIVIN	15	4.65e-02	-0.297000	4.83e-01
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	353	4.71e-02	0.061500	4.86e-01
REACTOME MTOR SIGNALLING	40	4.74e-02	-0.181000	4.86e-01
REACTOME TOLL LIKE RECEPTOR CASCADES	158	4.78e-02	-0.091200	4.87e-01
REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	12	4.87e-02	0.329000	4.88e-01
REACTOME ALPHA LINOLENIC OMEGA3 AND LINOLEIC OMEGA6 ACID METABOLISM	12	4.87e-02	-0.329000	4.88e-01
REACTOME METALLOTHIONEINS BIND METALS	11	4.88e-02	0.343000	4.88e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	11	4.93e-02	0.342000	4.91e-01
REACTOME CASPASE ACTIVATION VIA DEATH RECEPTORS IN THE PRESENCE OF LIGAND	16	5.09e-02	-0.282000	5.01e-01
REACTOME DEGRADATION OF AXIN	54	5.16e-02	0.153000	5.01e-01
REACTOME TRANSPORT OF RCBL WITHIN THE BODY	8	5.17e-02	-0.397000	5.01e-01
REACTOME FOLDING OF ACTIN BY CCT TRIC	10	5.17e-02	0.355000	5.01e-01
REACTOME RHO GTPASES ACTIVATE NADPH OXIDASES	21	5.20e-02	-0.245000	5.01e-01
REACTOME FGFR3B LIGAND BINDING AND ACTIVATION	7	5.25e-02	0.423000	5.01e-01
REACTOME NGF INDEPENDANT TRKA ACTIVATION	5	5.29e-02	0.500000	5.01e-01
REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	54	5.32e-02	0.152000	5.01e-01
REACTOME RHOU GTPASE CYCLE	37	5.36e-02	-0.183000	5.01e-01
REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	24	5.37e-02	-0.228000	5.01e-01
REACTOME TOXICITY OF BOTULINUM TOXIN TYPE D BOTD	5	5.40e-02	0.498000	5.01e-01
REACTOME PHENYLALANINE METABOLISM	6	5.41e-02	-0.454000	5.01e-01
REACTOME PERK REGULATES GENE EXPRESSION	31	5.58e-02	0.199000	5.11e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF MYELOID CELLS	7	5.58e-02	-0.418000	5.11e-01
REACTOME CA2 ACTIVATED K CHANNELS	9	5.64e-02	0.367000	5.15e-01
REACTOME RUNX2 REGULATES GENES INVOLVED IN CELL MIGRATION	8	5.69e-02	-0.389000	5.16e-01
REACTOME CHAPERONE MEDIATED AUTOPHAGY	20	5.77e-02	0.245000	5.19e-01
REACTOME INFECTIOUS DISEASE	910	5.79e-02	-0.037100	5.19e-01
REACTOME MELANIN BIOSYNTHESIS	5	5.81e-02	0.489000	5.19e-01
REACTOME RECEPTOR MEDIATED MITOPHAGY	10	5.90e-02	-0.345000	5.19e-01
REACTOME PHASE 2 PLATEAU PHASE	14	5.92e-02	-0.291000	5.19e-01
REACTOME THE ROLE OF GTSE1 IN G2 M PROGRESSION AFTER G2 CHECKPOINT	77	5.93e-02	0.124000	5.19e-01
REACTOME SCF SKP2 MEDIATED DEGRADATION OF P27 P21	59	5.94e-02	0.142000	5.19e-01
REACTOME RHO GTPASES ACTIVATE KTN1	11	6.00e-02	-0.327000	5.21e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL DEATH GENES	43	6.07e-02	-0.165000	5.24e-01
REACTOME GDP FUCOSE BIOSYNTHESIS	6	6.11e-02	-0.441000	5.26e-01
REACTOME VXPX CARGO TARGETING TO CILIUM	20	6.23e-02	-0.241000	5.33e-01
REACTOME SCAVENGING BY CLASS A RECEPTORS	19	6.27e-02	0.247000	5.33e-01
REACTOME ROS AND RNS PRODUCTION IN PHAGOCYTES	34	6.30e-02	-0.184000	5.33e-01
REACTOME CHOLESTEROL BIOSYNTHESIS	25	6.43e-02	-0.214000	5.35e-01
REACTOME SYNTHESIS OF GDP MANNOSE	5	6.45e-02	-0.477000	5.35e-01
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	98	6.53e-02	0.108000	5.35e-01
REACTOME ACTIVATION OF BH3 ONLY PROTEINS	30	6.55e-02	-0.194000	5.35e-01
REACTOME SARS COV 1 TARGETS HOST INTRACELLULAR SIGNALLING AND REGULATORY PATHWAYS	16	6.60e-02	-0.265000	5.35e-01
REACTOME METABOLISM OF AMINE DERIVED HORMONES	17	6.62e-02	0.257000	5.35e-01
REACTOME ESTROGEN DEPENDENT GENE EXPRESSION	140	6.70e-02	-0.089700	5.35e-01
REACTOME ERYTHROCYTES TAKE UP OXYGEN AND RELEASE CARBON DIOXIDE	9	6.70e-02	0.353000	5.35e-01
REACTOME BIOSYNTHESIS OF EPA DERIVED SPMS	6	6.72e-02	-0.431000	5.35e-01
REACTOME RHOJ GTPASE CYCLE	51	6.73e-02	-0.148000	5.35e-01
REACTOME CLEC7A DECTIN 1 INDUCES NFAT ACTIVATION	11	6.75e-02	-0.318000	5.35e-01
REACTOME PHENYLALANINE AND TYROSINE METABOLISM	11	6.78e-02	-0.318000	5.35e-01
REACTOME SULFIDE OXIDATION TO SULFATE	6	6.82e-02	-0.430000	5.35e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO LIPOGENESIS	9	6.91e-02	-0.350000	5.35e-01
REACTOME NF KB ACTIVATION THROUGH FADD RIP 1 PATHWAY MEDIATED BY CASPASE 8 AND 10	12	6.93e-02	-0.303000	5.35e-01
REACTOME MAP2K AND MAPK ACTIVATION	38	6.96e-02	-0.170000	5.35e-01
REACTOME COLLAGEN CHAIN TRIMERIZATION	42	6.98e-02	0.162000	5.35e-01
REACTOME GPER1 SIGNALING	45	7.01e-02	-0.156000	5.35e-01
REACTOME INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	28	7.02e-02	-0.198000	5.35e-01
REACTOME DEFECTIVE CFTR CAUSES CYSTIC FIBROSIS	60	7.04e-02	0.135000	5.35e-01
REACTOME REGULATION OF RUNX3 EXPRESSION AND ACTIVITY	54	7.08e-02	0.142000	5.35e-01
REACTOME HEME SIGNALING	47	7.11e-02	-0.152000	5.35e-01
REACTOME HCMV INFECTION	152	7.13e-02	-0.084800	5.35e-01
REACTOME P38MAPK EVENTS	13	7.14e-02	-0.289000	5.35e-01
REACTOME BUTYROPHILIN BTN FAMILY INTERACTIONS	12	7.15e-02	0.301000	5.35e-01
REACTOME NEGATIVE REGULATION OF NOTCH4 SIGNALING	53	7.17e-02	0.143000	5.35e-01
REACTOME DSCAM INTERACTIONS	11	7.27e-02	0.313000	5.38e-01
REACTOME BINDING OF TCF LEF CTNNB1 TO TARGET GENE PROMOTERS	8	7.28e-02	0.366000	5.38e-01
REACTOME RHOBTB3 ATPASE CYCLE	8	7.42e-02	-0.365000	5.42e-01
REACTOME REGULATION OF RAS BY GAPS	66	7.47e-02	0.127000	5.42e-01
REACTOME PHASE 1 INACTIVATION OF FAST NA CHANNELS	6	7.53e-02	0.419000	5.42e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 27 HYDROXYCHOLESTEROL	15	7.54e-02	0.265000	5.42e-01
REACTOME NRCAM INTERACTIONS	6	7.56e-02	0.419000	5.42e-01
REACTOME CARGO CONCENTRATION IN THE ER	32	7.56e-02	-0.181000	5.42e-01
REACTOME INITIAL TRIGGERING OF COMPLEMENT	21	7.56e-02	0.224000	5.42e-01
REACTOME SUPPRESSION OF PHAGOSOMAL MATURATION	13	7.68e-02	0.283000	5.46e-01
REACTOME NADE MODULATES DEATH SIGNALLING	5	7.71e-02	-0.457000	5.46e-01
REACTOME RHOV GTPASE CYCLE	36	7.74e-02	-0.170000	5.46e-01
REACTOME DIGESTION OF DIETARY LIPID	7	7.76e-02	0.385000	5.46e-01
REACTOME TRANSCRIPTION COUPLED NUCLEOTIDE EXCISION REPAIR TC NER	76	7.79e-02	-0.117000	5.46e-01
REACTOME METABOLISM OF NUCLEOTIDES	94	7.82e-02	-0.105000	5.46e-01
REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	91	7.88e-02	-0.107000	5.47e-01
REACTOME SIGNALING BY FLT3 FUSION PROTEINS	19	7.90e-02	-0.233000	5.47e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF GROWTH FACTORS AND THEIR RECEPTORS	14	8.09e-02	-0.269000	5.54e-01
REACTOME FICOLINS BIND TO REPETITIVE CARBOHYDRATE STRUCTURES ON THE TARGET CELL SURFACE	5	8.11e-02	0.450000	5.54e-01
REACTOME TRIGLYCERIDE METABOLISM	35	8.12e-02	0.170000	5.54e-01
REACTOME DIGESTION AND ABSORPTION	22	8.14e-02	0.215000	5.54e-01
REACTOME NUCLEOTIDE EXCISION REPAIR	107	8.16e-02	-0.097400	5.54e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX3	94	8.23e-02	0.104000	5.54e-01
REACTOME SIGNALING BY NUCLEAR RECEPTORS	283	8.33e-02	-0.059800	5.54e-01
REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	183	8.35e-02	-0.074200	5.54e-01
REACTOME SYNTHESIS OF KETONE BODIES	8	8.35e-02	-0.353000	5.54e-01
REACTOME TOLL LIKE RECEPTOR TLR1 TLR2 CASCADE	109	8.36e-02	-0.095900	5.54e-01
REACTOME DNA REPLICATION PRE INITIATION	150	8.38e-02	0.081800	5.54e-01
REACTOME NEUROTRANSMITTER RELEASE CYCLE	48	8.39e-02	0.144000	5.54e-01
REACTOME DEFECTIVE RIPK1 MEDIATED REGULATED NECROSIS	7	8.44e-02	-0.377000	5.55e-01
REACTOME KETONE BODY METABOLISM	9	8.52e-02	-0.331000	5.57e-01
REACTOME FATTY ACYL COA BIOSYNTHESIS	36	8.64e-02	-0.165000	5.63e-01
REACTOME METABOLISM OF WATER SOLUBLE VITAMINS AND COFACTORS	122	8.70e-02	-0.089700	5.65e-01
REACTOME DEFECTIVE CHST3 CAUSES SEDCJD	7	8.80e-02	0.372000	5.66e-01
REACTOME ADORA2B MEDIATED ANTI INFLAMMATORY CYTOKINES PRODUCTION	42	8.85e-02	-0.152000	5.66e-01
REACTOME MYD88 INDEPENDENT TLR4 CASCADE	103	8.89e-02	-0.097000	5.66e-01
REACTOME NONSENSE MEDIATED DECAY NMD	107	8.93e-02	0.095100	5.66e-01
REACTOME BIOSYNTHESIS OF MARESIN LIKE SPMS	6	8.94e-02	0.400000	5.66e-01
REACTOME REGULATION OF MECP2 EXPRESSION AND ACTIVITY	30	9.03e-02	-0.179000	5.66e-01
REACTOME POTENTIAL THERAPEUTICS FOR SARS	92	9.03e-02	-0.102000	5.66e-01
REACTOME INTERLEUKIN 37 SIGNALING	20	9.07e-02	-0.219000	5.66e-01
REACTOME RAB GEFS EXCHANGE GTP FOR GDP ON RABS	81	9.16e-02	-0.108000	5.66e-01
REACTOME ACTIVATION OF NMDA RECEPTORS AND POSTSYNAPTIC EVENTS	87	9.17e-02	-0.105000	5.66e-01
REACTOME GLI PROTEINS BIND PROMOTERS OF HH RESPONSIVE GENES TO PROMOTE TRANSCRIPTION	7	9.19e-02	0.368000	5.66e-01
REACTOME MITOCHONDRIAL CALCIUM ION TRANSPORT	23	9.28e-02	-0.202000	5.66e-01
REACTOME VOLTAGE GATED POTASSIUM CHANNELS	42	9.30e-02	0.150000	5.66e-01
REACTOME CYTOSOLIC IRON SULFUR CLUSTER ASSEMBLY	12	9.32e-02	-0.280000	5.66e-01
REACTOME BIOTIN TRANSPORT AND METABOLISM	10	9.33e-02	-0.306000	5.66e-01
REACTOME MICRORNA MIRNA BIOGENESIS	25	9.36e-02	-0.194000	5.66e-01
REACTOME ASYMMETRIC LOCALIZATION OF PCP PROTEINS	63	9.38e-02	0.122000	5.66e-01
REACTOME NEGATIVE REGULATION OF FLT3	15	9.49e-02	0.249000	5.66e-01
REACTOME GLUTAMATE AND GLUTAMINE METABOLISM	13	9.50e-02	-0.267000	5.66e-01
REACTOME TP53 REGULATES METABOLIC GENES	81	9.53e-02	-0.107000	5.66e-01
REACTOME ERK MAPK TARGETS	20	9.56e-02	-0.215000	5.66e-01
REACTOME CARNITINE METABOLISM	13	9.61e-02	-0.267000	5.66e-01
REACTOME DEFECTS IN VITAMIN AND COFACTOR METABOLISM	21	9.61e-02	-0.210000	5.66e-01
REACTOME ABC TRANSPORTER DISORDERS	76	9.61e-02	0.110000	5.66e-01
REACTOME SOS MEDIATED SIGNALLING	7	9.63e-02	-0.363000	5.66e-01
REACTOME SEALING OF THE NUCLEAR ENVELOPE NE BY ESCRT III	31	9.70e-02	-0.172000	5.66e-01
REACTOME NUCLEAR ENVELOPE NE REASSEMBLY	74	9.75e-02	-0.111000	5.66e-01
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	81	9.76e-02	-0.106000	5.66e-01
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	28	9.77e-02	0.181000	5.66e-01
REACTOME AMINO ACIDS REGULATE MTORC1	53	9.78e-02	-0.131000	5.66e-01
REACTOME GLYCOGEN SYNTHESIS	13	9.85e-02	0.265000	5.66e-01
REACTOME EGR2 AND SOX10 MEDIATED INITIATION OF SCHWANN CELL MYELINATION	27	9.86e-02	-0.184000	5.66e-01
REACTOME FCGR3A MEDIATED IL10 SYNTHESIS	36	9.87e-02	-0.159000	5.66e-01
REACTOME AMINO ACID CONJUGATION	9	9.96e-02	0.317000	5.66e-01
REACTOME PREDNISONE ADME	10	9.98e-02	0.301000	5.66e-01
REACTOME MITOTIC PROMETAPHASE	194	1.00e-01	-0.068500	5.66e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY DVL INTERACTING PROTEINS	5	1.00e-01	-0.425000	5.66e-01
REACTOME CD28 DEPENDENT VAV1 PATHWAY	11	1.00e-01	0.286000	5.66e-01
REACTOME CD209 DC SIGN SIGNALING	20	1.01e-01	-0.212000	5.66e-01
REACTOME DETOXIFICATION OF REACTIVE OXYGEN SPECIES	34	1.01e-01	-0.162000	5.66e-01
REACTOME DEFECTIVE CSF2RB CAUSES SMDP5	7	1.02e-01	-0.357000	5.66e-01
REACTOME REGULATION OF SIGNALING BY CBL	22	1.02e-01	0.202000	5.66e-01
REACTOME GLYCOSAMINOGLYCAN METABOLISM	118	1.02e-01	-0.087100	5.67e-01
REACTOME ACTIVATION OF THE PHOTOTRANSDUCTION CASCADE	11	1.03e-01	-0.284000	5.69e-01
REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	23	1.04e-01	-0.196000	5.73e-01
REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	21	1.04e-01	0.205000	5.73e-01
REACTOME HATS ACETYLATE HISTONES	129	1.05e-01	-0.082600	5.74e-01
REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	263	1.05e-01	-0.058000	5.74e-01
REACTOME INSULIN RECEPTOR RECYCLING	29	1.06e-01	-0.174000	5.74e-01
REACTOME DEGRADATION OF DVL	56	1.06e-01	0.125000	5.74e-01
REACTOME SYNTHESIS OF LIPOXINS LX	6	1.08e-01	-0.379000	5.78e-01
REACTOME DIGESTION	17	1.08e-01	0.225000	5.78e-01
REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	52	1.08e-01	-0.129000	5.78e-01
REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	24	1.08e-01	0.189000	5.78e-01
REACTOME DEATH RECEPTOR SIGNALING	143	1.09e-01	-0.077700	5.78e-01
REACTOME SARS COV 2 MODULATES HOST TRANSLATION MACHINERY	46	1.11e-01	0.136000	5.87e-01
REACTOME POU5F1 OCT4 SOX2 NANOG REPRESS GENES RELATED TO DIFFERENTIATION	10	1.11e-01	-0.291000	5.87e-01
REACTOME AUTOPHAGY	144	1.11e-01	-0.076900	5.87e-01
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	122	1.12e-01	0.083400	5.88e-01
REACTOME INTEGRATION OF ENERGY METABOLISM	105	1.13e-01	-0.089600	5.91e-01
REACTOME MUSCARINIC ACETYLCHOLINE RECEPTORS	5	1.13e-01	-0.409000	5.91e-01
REACTOME CILIUM ASSEMBLY	190	1.13e-01	-0.066600	5.91e-01
REACTOME ER TO GOLGI ANTEROGRADE TRANSPORT	152	1.15e-01	-0.074100	5.94e-01
REACTOME CELLULAR RESPONSE TO CHEMICAL STRESS	188	1.15e-01	-0.066600	5.94e-01
REACTOME DISEASES ASSOCIATED WITH SURFACTANT METABOLISM	9	1.15e-01	-0.303000	5.94e-01
REACTOME FATTY ACIDS	15	1.15e-01	0.235000	5.94e-01
REACTOME PROTEIN METHYLATION	17	1.16e-01	-0.220000	5.95e-01
REACTOME EICOSANOIDS	12	1.16e-01	0.262000	5.95e-01
REACTOME GLUTATHIONE SYNTHESIS AND RECYCLING	12	1.17e-01	-0.261000	5.97e-01
REACTOME MRNA EDITING	10	1.18e-01	0.286000	5.97e-01
REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	55	1.18e-01	0.122000	5.97e-01
REACTOME GOLGI TO ER RETROGRADE TRANSPORT	132	1.18e-01	-0.078700	5.97e-01
REACTOME SYNTHESIS OF PA	38	1.19e-01	-0.146000	6.00e-01
REACTOME NON INTEGRIN MEMBRANE ECM INTERACTIONS	55	1.20e-01	0.121000	6.00e-01
REACTOME HEDGEHOG LIGAND BIOGENESIS	64	1.20e-01	0.112000	6.00e-01
REACTOME PEXOPHAGY	11	1.21e-01	0.270000	6.01e-01
REACTOME SIGNALING BY RECEPTOR TYROSINE KINASES	507	1.21e-01	-0.040200	6.01e-01
REACTOME MAPK3 ERK1 ACTIVATION	10	1.22e-01	-0.282000	6.01e-01
REACTOME SIGNALLING TO ERKS	34	1.23e-01	-0.153000	6.01e-01
REACTOME GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	34	1.23e-01	-0.153000	6.01e-01
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	29	1.24e-01	-0.165000	6.01e-01
REACTOME METABOLISM OF POLYAMINES	56	1.24e-01	0.119000	6.01e-01
REACTOME CLATHRIN MEDIATED ENDOCYTOSIS	139	1.24e-01	-0.075500	6.01e-01
REACTOME PENTOSE PHOSPHATE PATHWAY	12	1.24e-01	-0.256000	6.01e-01
REACTOME RMTS METHYLATE HISTONE ARGININES	72	1.24e-01	-0.105000	6.01e-01
REACTOME DAG AND IP3 SIGNALING	40	1.25e-01	-0.140000	6.01e-01
REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	30	1.25e-01	-0.162000	6.01e-01
REACTOME CGMP EFFECTS	16	1.25e-01	0.221000	6.01e-01
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	66	1.25e-01	0.109000	6.01e-01
REACTOME AQUAPORIN MEDIATED TRANSPORT	51	1.26e-01	-0.124000	6.01e-01
REACTOME BILE ACID AND BILE SALT METABOLISM	45	1.26e-01	0.132000	6.01e-01
REACTOME PREGNENOLONE BIOSYNTHESIS	12	1.26e-01	-0.255000	6.01e-01
REACTOME BASE EXCISION REPAIR AP SITE FORMATION	59	1.27e-01	0.115000	6.02e-01
REACTOME CELLULAR RESPONSE TO HYPOXIA	74	1.28e-01	0.102000	6.04e-01
REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	46	1.29e-01	0.129000	6.06e-01
REACTOME G1 S DNA DAMAGE CHECKPOINTS	67	1.29e-01	0.107000	6.06e-01
REACTOME REGULATION OF GENE EXPRESSION IN ENDOCRINE COMMITTED NEUROG3 PROGENITOR CELLS	5	1.29e-01	0.392000	6.06e-01
REACTOME HEMOSTASIS	591	1.30e-01	-0.036400	6.07e-01
REACTOME BIOSYNTHESIS OF MARESINS	8	1.31e-01	0.309000	6.07e-01
REACTOME DEFECTIVE FACTOR IX CAUSES HEMOPHILIA B	7	1.31e-01	0.330000	6.07e-01
REACTOME THE PHOTOTRANSDUCTION CASCADE	32	1.31e-01	-0.154000	6.07e-01
REACTOME HIGHLY CALCIUM PERMEABLE NICOTINIC ACETYLCHOLINE RECEPTORS	9	1.32e-01	0.290000	6.07e-01
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION	250	1.32e-01	-0.055300	6.07e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII CAMKK CAMKIV CASCASDE	8	1.32e-01	-0.307000	6.07e-01
REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	32	1.33e-01	-0.154000	6.07e-01
REACTOME PEPTIDE HORMONE METABOLISM	84	1.33e-01	-0.094800	6.07e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DEATH RECEPTORS AND LIGANDS	12	1.33e-01	-0.250000	6.07e-01
REACTOME GLYCEROPHOSPHOLIPID CATABOLISM	7	1.35e-01	-0.327000	6.12e-01
REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN GENE EXPRESSION	26	1.35e-01	-0.169000	6.14e-01
REACTOME DEFECTIVE C1GALT1C1 CAUSES TNPS	16	1.36e-01	0.215000	6.14e-01
REACTOME DEFECTIVE CHST6 CAUSES MCDC1	8	1.37e-01	0.304000	6.14e-01
REACTOME SYNTHESIS OF PE	13	1.37e-01	-0.238000	6.14e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF HSCS	121	1.37e-01	0.078300	6.14e-01
REACTOME ASSEMBLY OF ACTIVE LPL AND LIPC LIPASE COMPLEXES	18	1.37e-01	-0.202000	6.14e-01
REACTOME NFE2L2 REGULATING ANTI OXIDANT DETOXIFICATION ENZYMES	17	1.38e-01	-0.208000	6.14e-01
REACTOME NEUROTOXICITY OF CLOSTRIDIUM TOXINS	10	1.38e-01	0.271000	6.14e-01
REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	78	1.39e-01	-0.097000	6.14e-01
REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	12	1.39e-01	0.247000	6.14e-01
REACTOME NEUROTRANSMITTER RECEPTORS AND POSTSYNAPTIC SIGNAL TRANSMISSION	193	1.39e-01	-0.061800	6.14e-01
REACTOME CHREBP ACTIVATES METABOLIC GENE EXPRESSION	8	1.40e-01	-0.302000	6.15e-01
REACTOME GLYCOGEN STORAGE DISEASES	15	1.41e-01	0.219000	6.16e-01
REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	160	1.41e-01	-0.067400	6.16e-01
REACTOME TRANSLESION SYNTHESIS BY POLH	19	1.42e-01	0.194000	6.16e-01
REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	19	1.42e-01	0.194000	6.16e-01
REACTOME NOTCH4 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	19	1.42e-01	-0.194000	6.16e-01
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	28	1.43e-01	-0.160000	6.16e-01
REACTOME CA DEPENDENT EVENTS	36	1.43e-01	-0.141000	6.16e-01
REACTOME OPIOID SIGNALLING	89	1.43e-01	-0.089800	6.16e-01
REACTOME AMYLOID FIBER FORMATION	102	1.44e-01	0.083800	6.17e-01
REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	17	1.44e-01	-0.205000	6.17e-01
REACTOME PI3K AKT ACTIVATION	9	1.44e-01	-0.281000	6.17e-01
REACTOME ATF4 ACTIVATES GENES IN RESPONSE TO ENDOPLASMIC RETICULUM STRESS	27	1.46e-01	0.162000	6.19e-01
REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	11	1.46e-01	0.253000	6.19e-01
REACTOME HEDGEHOG OFF STATE	111	1.46e-01	0.079800	6.19e-01
REACTOME ERKS ARE INACTIVATED	13	1.47e-01	-0.232000	6.19e-01
REACTOME CASPASE ACTIVATION VIA DEPENDENCE RECEPTORS IN THE ABSENCE OF LIGAND	9	1.47e-01	-0.279000	6.19e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NUDT PROTEINS	7	1.47e-01	-0.317000	6.19e-01
REACTOME PROLONGED ERK ACTIVATION EVENTS	14	1.48e-01	-0.223000	6.21e-01
REACTOME PHASE II CONJUGATION OF COMPOUNDS	102	1.49e-01	0.082800	6.22e-01
REACTOME INTEGRIN CELL SURFACE INTERACTIONS	83	1.50e-01	0.091400	6.26e-01
REACTOME SHC MEDIATED CASCADE FGFR4	19	1.50e-01	0.191000	6.26e-01
REACTOME REGULATION OF IFNG SIGNALING	14	1.51e-01	-0.222000	6.26e-01
REACTOME PI 3K CASCADE FGFR3	17	1.51e-01	0.201000	6.28e-01
REACTOME CATION COUPLED CHLORIDE COTRANSPORTERS	7	1.52e-01	-0.313000	6.28e-01
REACTOME SYNTHESIS OF LEUKOTRIENES LT AND EOXINS EX	21	1.52e-01	-0.180000	6.28e-01
REACTOME DOWNREGULATION OF ERBB4 SIGNALING	9	1.53e-01	0.275000	6.29e-01
REACTOME FGFR3 LIGAND BINDING AND ACTIVATION	12	1.57e-01	0.236000	6.42e-01
REACTOME IRF3 MEDIATED INDUCTION OF TYPE I IFN	13	1.57e-01	-0.227000	6.42e-01
REACTOME ERYTHROPOIETIN ACTIVATES STAT5	7	1.58e-01	-0.308000	6.45e-01
REACTOME DEFECTIVE ST3GAL3 CAUSES MCT12 AND EIEE15	8	1.60e-01	0.287000	6.50e-01
REACTOME METABOLISM OF STEROIDS	150	1.60e-01	-0.066400	6.51e-01
REACTOME INTERFERON ALPHA BETA SIGNALING	70	1.61e-01	0.097000	6.51e-01
REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	13	1.63e-01	0.223000	6.56e-01
REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	31	1.64e-01	-0.144000	6.56e-01
REACTOME ACTIVATION OF MATRIX METALLOPROTEINASES	30	1.65e-01	-0.147000	6.56e-01
REACTOME REDUCTION OF CYTOSOLIC CA LEVELS	11	1.65e-01	-0.242000	6.56e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FYN	7	1.65e-01	-0.303000	6.56e-01
REACTOME SARS COV 1 MODULATES HOST TRANSLATION MACHINERY	33	1.65e-01	0.140000	6.56e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES	33	1.65e-01	-0.140000	6.56e-01
REACTOME TNFR2 NON CANONICAL NF KB PATHWAY	96	1.65e-01	0.081900	6.56e-01
REACTOME EXTRA NUCLEAR ESTROGEN SIGNALING	74	1.66e-01	-0.093100	6.56e-01
REACTOME TRANSLATION OF REPLICASE AND ASSEMBLY OF THE REPLICATION TRANSCRIPTION COMPLEX	14	1.66e-01	-0.214000	6.56e-01
REACTOME SUMOYLATION OF TRANSCRIPTION COFACTORS	43	1.66e-01	-0.122000	6.56e-01
REACTOME WNT LIGAND BIOGENESIS AND TRAFFICKING	25	1.67e-01	0.160000	6.57e-01
REACTOME PHOSPHORYLATION OF THE APC C	20	1.68e-01	0.178000	6.61e-01
REACTOME ACYL CHAIN REMODELING OF DAG AND TAG	5	1.70e-01	-0.354000	6.62e-01
REACTOME PYRUVATE METABOLISM	29	1.71e-01	-0.147000	6.62e-01
REACTOME BLOOD GROUP SYSTEMS BIOSYNTHESIS	21	1.71e-01	-0.173000	6.62e-01
REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	48	1.71e-01	-0.114000	6.62e-01
REACTOME DEFECTIVE FACTOR VIII CAUSES HEMOPHILIA A	5	1.72e-01	-0.353000	6.62e-01
REACTOME TICAM1 DEPENDENT ACTIVATION OF IRF3 IRF7	12	1.72e-01	0.228000	6.62e-01
REACTOME ACTIVATION OF TRKA RECEPTORS	6	1.72e-01	0.322000	6.62e-01
REACTOME PHASE 0 RAPID DEPOLARISATION	31	1.73e-01	0.142000	6.62e-01
REACTOME FORMATION OF TC NER PRE INCISION COMPLEX	51	1.73e-01	-0.110000	6.62e-01
REACTOME P75NTR REGULATES AXONOGENESIS	9	1.73e-01	-0.262000	6.62e-01
REACTOME TNFR1 INDUCED PROAPOPTOTIC SIGNALING	23	1.74e-01	-0.164000	6.62e-01
REACTOME NERVOUS SYSTEM DEVELOPMENT	552	1.74e-01	0.033900	6.62e-01
REACTOME MRNA SPLICING	197	1.74e-01	-0.056200	6.62e-01
REACTOME CONSTITUTIVE SIGNALING BY ABERRANT PI3K IN CANCER	77	1.75e-01	0.089500	6.63e-01
REACTOME HUR ELAVL1 BINDS AND STABILIZES MRNA	8	1.75e-01	-0.277000	6.63e-01
REACTOME M PHASE	398	1.76e-01	-0.039500	6.65e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G1 CELL CYCLE ARREST	14	1.76e-01	-0.209000	6.65e-01
REACTOME NCAM1 INTERACTIONS	41	1.78e-01	0.121000	6.71e-01
REACTOME P75NTR SIGNALS VIA NF KB	15	1.79e-01	0.200000	6.71e-01
REACTOME TRANSCRIPTIONAL REGULATION BY E2F6	32	1.80e-01	-0.137000	6.71e-01
REACTOME SIGNALING BY INSULIN RECEPTOR	80	1.80e-01	-0.086800	6.71e-01
REACTOME NRAGE SIGNALS DEATH THROUGH JNK	53	1.80e-01	-0.107000	6.71e-01
REACTOME MITOCHONDRIAL IRON SULFUR CLUSTER BIOGENESIS	13	1.81e-01	-0.214000	6.73e-01
REACTOME DISEASES OF SIGNAL TRANSDUCTION BY GROWTH FACTOR RECEPTORS AND SECOND MESSENGERS	418	1.82e-01	-0.038100	6.75e-01
REACTOME DEFECTIVE B4GALT7 CAUSES EDS PROGEROID TYPE	17	1.82e-01	0.187000	6.75e-01
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	12	1.83e-01	-0.222000	6.75e-01
REACTOME COPI DEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	98	1.83e-01	-0.077800	6.75e-01
REACTOME TRANSCRIPTIONAL REGULATION BY MECP2	60	1.85e-01	-0.099000	6.80e-01
REACTOME PTEN REGULATION	135	1.86e-01	-0.065900	6.80e-01
REACTOME INTRINSIC PATHWAY OF FIBRIN CLOT FORMATION	21	1.86e-01	0.167000	6.80e-01
REACTOME ERYTHROCYTES TAKE UP CARBON DIOXIDE AND RELEASE OXYGEN	13	1.88e-01	0.211000	6.80e-01
REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	19	1.88e-01	0.174000	6.80e-01
REACTOME UPTAKE OF DIETARY COBALAMINS INTO ENTEROCYTES	9	1.88e-01	-0.253000	6.80e-01
REACTOME SIGNALING BY HIPPO	19	1.89e-01	-0.174000	6.80e-01
REACTOME REGULATION OF FZD BY UBIQUITINATION	21	1.89e-01	0.166000	6.80e-01
REACTOME DEFECTIVE GALNT3 CAUSES HFTC	16	1.89e-01	0.190000	6.80e-01
REACTOME REGULATION OF LOCALIZATION OF FOXO TRANSCRIPTION FACTORS	11	1.89e-01	-0.229000	6.80e-01
REACTOME PINK1 PRKN MEDIATED MITOPHAGY	22	1.89e-01	0.162000	6.80e-01
REACTOME DNA DOUBLE STRAND BREAK REPAIR	162	1.89e-01	-0.059800	6.80e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	14	1.90e-01	0.202000	6.82e-01
REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	19	1.92e-01	-0.173000	6.88e-01
REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	86	1.93e-01	0.081200	6.88e-01
REACTOME ENDOSOMAL VACUOLAR PATHWAY	11	1.93e-01	0.227000	6.88e-01
REACTOME DEFECTIVE LFNG CAUSES SCDO3	5	1.95e-01	-0.335000	6.91e-01
REACTOME SIGNALING BY NTRKS	132	1.96e-01	-0.065200	6.92e-01
REACTOME VLDLR INTERNALISATION AND DEGRADATION	16	1.97e-01	0.186000	6.92e-01
REACTOME RUNX3 REGULATES NOTCH SIGNALING	13	1.97e-01	-0.207000	6.92e-01
REACTOME P2Y RECEPTORS	9	1.97e-01	-0.248000	6.92e-01
REACTOME RELEASE OF APOPTOTIC FACTORS FROM THE MITOCHONDRIA	7	1.97e-01	0.281000	6.92e-01
REACTOME DEGRADATION OF BETA CATENIN BY THE DESTRUCTION COMPLEX	83	1.98e-01	0.081800	6.92e-01
REACTOME NEGATIVE REGULATION OF FGFR4 SIGNALING	30	1.98e-01	0.136000	6.92e-01
REACTOME REGULATION OF TP53 ACTIVITY	156	1.99e-01	-0.059600	6.92e-01
REACTOME INTERLEUKIN 17 SIGNALING	66	1.99e-01	-0.091400	6.92e-01
REACTOME REGULATION OF FOXO TRANSCRIPTIONAL ACTIVITY BY ACETYLATION	9	1.99e-01	-0.247000	6.92e-01
REACTOME ARYL HYDROCARBON RECEPTOR SIGNALLING	6	1.99e-01	0.302000	6.92e-01
REACTOME THE CANONICAL RETINOID CYCLE IN RODS TWILIGHT VISION	23	2.00e-01	-0.154000	6.93e-01
REACTOME TRANSPORT OF SMALL MOLECULES	697	2.01e-01	-0.028400	6.94e-01
REACTOME RECOGNITION AND ASSOCIATION OF DNA GLYCOSYLASE WITH SITE CONTAINING AN AFFECTED PURINE	52	2.01e-01	0.102000	6.95e-01
REACTOME CONSTITUTIVE SIGNALING BY OVEREXPRESSED ERBB2	11	2.02e-01	-0.222000	6.95e-01
REACTOME ELASTIC FIBRE FORMATION	44	2.04e-01	-0.111000	6.99e-01
REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX	9	2.06e-01	0.244000	6.99e-01
REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	99	2.06e-01	0.073600	6.99e-01
REACTOME DEFECTIVE INTRINSIC PATHWAY FOR APOPTOSIS	25	2.06e-01	-0.146000	6.99e-01
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	54	2.06e-01	-0.099400	6.99e-01
REACTOME MUCOPOLYSACCHARIDOSES	10	2.07e-01	-0.230000	6.99e-01
REACTOME INOSITOL PHOSPHATE METABOLISM	45	2.08e-01	-0.109000	6.99e-01
REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	22	2.08e-01	0.155000	6.99e-01
REACTOME TRANSCRIPTIONAL REGULATION OF PLURIPOTENT STEM CELLS	29	2.08e-01	-0.135000	6.99e-01
REACTOME G ALPHA Q SIGNALLING EVENTS	206	2.08e-01	-0.050900	6.99e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	34	2.08e-01	0.125000	6.99e-01
REACTOME SHC1 EVENTS IN EGFR SIGNALING	14	2.09e-01	-0.194000	6.99e-01
REACTOME RRNA PROCESSING	192	2.09e-01	0.052600	6.99e-01
REACTOME TICAM1 TRAF6 DEPENDENT INDUCTION OF TAK1 COMPLEX	10	2.09e-01	0.229000	6.99e-01
REACTOME TOLL LIKE RECEPTOR 9 TLR9 CASCADE	100	2.10e-01	-0.072600	6.99e-01
REACTOME TICAM1 RIP1 MEDIATED IKK COMPLEX RECRUITMENT	18	2.10e-01	0.171000	6.99e-01
REACTOME RND2 GTPASE CYCLE	42	2.11e-01	-0.111000	7.02e-01
REACTOME INLB MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELL	14	2.12e-01	0.193000	7.02e-01
REACTOME RUNX3 REGULATES YAP1 MEDIATED TRANSCRIPTION	8	2.13e-01	0.255000	7.02e-01
REACTOME HEME DEGRADATION	15	2.13e-01	0.186000	7.02e-01
REACTOME NOD1 2 SIGNALING PATHWAY	33	2.15e-01	0.125000	7.08e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN INTERLEUKIN SIGNALING	5	2.15e-01	-0.320000	7.08e-01
REACTOME SIGNALING BY EGFR	49	2.16e-01	-0.102000	7.08e-01
REACTOME RECYCLING PATHWAY OF L1	43	2.16e-01	-0.109000	7.08e-01
REACTOME SYNTHESIS OF PYROPHOSPHATES IN THE CYTOSOL	8	2.19e-01	-0.251000	7.16e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION	1336	2.19e-01	-0.020000	7.16e-01
REACTOME SENSORY PROCESSING OF SOUND	72	2.20e-01	0.083600	7.17e-01
REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	134	2.21e-01	-0.061300	7.17e-01
REACTOME SUMOYLATION OF DNA METHYLATION PROTEINS	16	2.22e-01	-0.176000	7.19e-01
REACTOME MHC CLASS II ANTIGEN PRESENTATION	121	2.23e-01	-0.064200	7.21e-01
REACTOME EPHB MEDIATED FORWARD SIGNALING	41	2.25e-01	-0.110000	7.26e-01
REACTOME FGFR1C LIGAND BINDING AND ACTIVATION	11	2.26e-01	0.211000	7.28e-01
REACTOME FORMATION OF SENESCENCE ASSOCIATED HETEROCHROMATIN FOCI SAHF	17	2.28e-01	-0.169000	7.33e-01
REACTOME SIGNALLING TO RAS	20	2.30e-01	-0.155000	7.36e-01
REACTOME RAF INDEPENDENT MAPK1 3 ACTIVATION	22	2.31e-01	-0.148000	7.36e-01
REACTOME ADRENOCEPTORS	9	2.31e-01	0.230000	7.36e-01
REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	67	2.32e-01	-0.084500	7.36e-01
REACTOME SIGNALING BY FLT3 ITD AND TKD MUTANTS	16	2.32e-01	-0.173000	7.36e-01
REACTOME RESPONSE TO METAL IONS	14	2.32e-01	0.184000	7.36e-01
REACTOME SYNTHESIS OF IP2 IP AND INS IN THE CYTOSOL	13	2.33e-01	-0.191000	7.36e-01
REACTOME FORMATION OF THE EARLY ELONGATION COMPLEX	32	2.33e-01	-0.122000	7.36e-01
REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	11	2.33e-01	-0.208000	7.36e-01
REACTOME INTERFERON GAMMA SIGNALING	88	2.33e-01	0.073500	7.36e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF OXIDATIVE STRESS METABOLIC AND NEURONAL GENES	29	2.34e-01	0.128000	7.36e-01
REACTOME REGULATION OF RUNX2 EXPRESSION AND ACTIVITY	72	2.34e-01	0.081000	7.36e-01
REACTOME CD22 MEDIATED BCR REGULATION	5	2.35e-01	0.307000	7.36e-01
REACTOME INTERACTION WITH CUMULUS CELLS AND THE ZONA PELLUCIDA	11	2.35e-01	0.207000	7.36e-01
REACTOME DEFECTS IN BIOTIN BTN METABOLISM	8	2.36e-01	-0.242000	7.36e-01
REACTOME DEFECTS IN COBALAMIN B12 METABOLISM	13	2.36e-01	-0.190000	7.36e-01
REACTOME HEDGEHOG ON STATE	85	2.37e-01	0.074200	7.36e-01
REACTOME ERYTHROPOIETIN ACTIVATES RAS	14	2.37e-01	-0.183000	7.36e-01
REACTOME DECTIN 1 MEDIATED NONCANONICAL NF KB SIGNALING	61	2.37e-01	0.087500	7.36e-01
REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF TRANSPORT AND UPTAKE BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	118	2.37e-01	0.063000	7.36e-01
REACTOME ALPHA PROTEIN KINASE 1 SIGNALING PATHWAY	10	2.40e-01	0.214000	7.42e-01
REACTOME MAP3K8 TPL2 DEPENDENT MAPK1 3 ACTIVATION	15	2.41e-01	0.175000	7.42e-01
REACTOME INFLAMMASOMES	21	2.41e-01	-0.148000	7.42e-01
REACTOME TIGHT JUNCTION INTERACTIONS	29	2.42e-01	0.126000	7.42e-01
REACTOME PTK6 REGULATES PROTEINS INVOLVED IN RNA PROCESSING	5	2.42e-01	-0.302000	7.42e-01
REACTOME HSF1 ACTIVATION	29	2.42e-01	0.125000	7.42e-01
REACTOME REGULATION OF RUNX1 EXPRESSION AND ACTIVITY	17	2.43e-01	-0.163000	7.42e-01
REACTOME ESTROGEN DEPENDENT NUCLEAR EVENTS DOWNSTREAM OF ESR MEMBRANE SIGNALING	23	2.43e-01	-0.141000	7.42e-01
REACTOME TLR3 MEDIATED TICAM1 DEPENDENT PROGRAMMED CELL DEATH	6	2.44e-01	-0.275000	7.42e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR4	26	2.45e-01	0.132000	7.43e-01
REACTOME FGFR2 LIGAND BINDING AND ACTIVATION	19	2.45e-01	0.154000	7.43e-01
REACTOME ABORTIVE ELONGATION OF HIV 1 TRANSCRIPT IN THE ABSENCE OF TAT	23	2.46e-01	-0.140000	7.43e-01
REACTOME PLASMA LIPOPROTEIN REMODELING	33	2.46e-01	-0.117000	7.43e-01
REACTOME SIGNALING BY ERYTHROPOIETIN	25	2.46e-01	-0.134000	7.43e-01
REACTOME BINDING AND UPTAKE OF LIGANDS BY SCAVENGER RECEPTORS	42	2.47e-01	0.103000	7.43e-01
REACTOME CHYLOMICRON REMODELING	10	2.47e-01	-0.211000	7.43e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOINOSITIDE 3 KINASE PI3K	12	2.48e-01	-0.192000	7.45e-01
REACTOME INTRA GOLGI AND RETROGRADE GOLGI TO ER TRAFFIC	198	2.51e-01	-0.047300	7.45e-01
REACTOME SYNTHESIS OF ACTIVE UBIQUITIN ROLES OF E1 AND E2 ENZYMES	27	2.51e-01	0.128000	7.45e-01
REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	24	2.52e-01	0.135000	7.45e-01
REACTOME NOTCH2 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	22	2.52e-01	0.141000	7.45e-01
REACTOME EPH EPHRIN SIGNALING	90	2.52e-01	-0.069900	7.45e-01
REACTOME ACYL CHAIN REMODELLING OF PC	27	2.52e-01	-0.127000	7.45e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN WNT SIGNALING	5	2.52e-01	-0.296000	7.45e-01
REACTOME METABOLISM OF ANGIOTENSINOGEN TO ANGIOTENSINS	16	2.52e-01	-0.165000	7.45e-01
REACTOME PEPTIDE HORMONE BIOSYNTHESIS	13	2.52e-01	-0.183000	7.45e-01
REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	28	2.53e-01	0.125000	7.46e-01
REACTOME SIGNALING BY MAPK MUTANTS	6	2.54e-01	-0.269000	7.48e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION INITIATION	45	2.55e-01	-0.098000	7.50e-01
REACTOME TRANSLOCATION OF SLC2A4 GLUT4 TO THE PLASMA MEMBRANE	71	2.56e-01	-0.078000	7.50e-01
REACTOME GRB7 EVENTS IN ERBB2 SIGNALING	5	2.58e-01	0.292000	7.50e-01
REACTOME DNA DAMAGE REVERSAL	8	2.58e-01	-0.231000	7.50e-01
REACTOME RAS ACTIVATION UPON CA2 INFLUX THROUGH NMDA RECEPTOR	19	2.58e-01	-0.150000	7.50e-01
REACTOME SWITCHING OF ORIGINS TO A POST REPLICATIVE STATE	91	2.59e-01	0.068500	7.50e-01
REACTOME MATURATION OF SARS COV 1 SPIKE PROTEIN	5	2.60e-01	-0.291000	7.50e-01
REACTOME MATURATION OF PROTEIN 3A	9	2.60e-01	-0.217000	7.50e-01
REACTOME N GLYCAN ANTENNAE ELONGATION	15	2.61e-01	-0.168000	7.50e-01
REACTOME SYNTHESIS OF PC	27	2.61e-01	-0.125000	7.50e-01
REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	51	2.61e-01	-0.090900	7.50e-01
REACTOME MTORC1 MEDIATED SIGNALLING	23	2.62e-01	-0.135000	7.50e-01
REACTOME SODIUM CALCIUM EXCHANGERS	11	2.63e-01	-0.195000	7.50e-01
REACTOME REGULATION OF CYTOSKELETAL REMODELING AND CELL SPREADING BY IPP COMPLEX COMPONENTS	7	2.64e-01	-0.244000	7.50e-01
REACTOME CHL1 INTERACTIONS	9	2.64e-01	-0.215000	7.50e-01
REACTOME CYTOPROTECTION BY HMOX1	59	2.65e-01	-0.084000	7.50e-01
REACTOME G2 M CHECKPOINTS	162	2.65e-01	0.050800	7.50e-01
REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	17	2.65e-01	-0.156000	7.50e-01
REACTOME RAS PROCESSING	22	2.65e-01	-0.137000	7.50e-01
REACTOME LTC4 CYSLTR MEDIATED IL4 PRODUCTION	6	2.65e-01	-0.263000	7.50e-01
REACTOME INTERLEUKIN RECEPTOR SHC SIGNALING	24	2.65e-01	-0.131000	7.50e-01
REACTOME NEGATIVE REGULATION OF MAPK PATHWAY	41	2.66e-01	-0.100000	7.50e-01
REACTOME PKA ACTIVATION IN GLUCAGON SIGNALLING	17	2.66e-01	-0.156000	7.50e-01
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	122	2.66e-01	-0.058300	7.50e-01
REACTOME UNWINDING OF DNA	12	2.66e-01	-0.185000	7.50e-01
REACTOME METABOLISM OF STEROID HORMONES	35	2.67e-01	-0.108000	7.51e-01
REACTOME FBXW7 MUTANTS AND NOTCH1 IN CANCER	5	2.68e-01	-0.286000	7.51e-01
REACTOME GLOBAL GENOME NUCLEOTIDE EXCISION REPAIR GG NER	81	2.68e-01	-0.071100	7.51e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CASPASE ACTIVATORS AND CASPASES	12	2.70e-01	-0.184000	7.51e-01
REACTOME LIGAND RECEPTOR INTERACTIONS	8	2.70e-01	0.225000	7.51e-01
REACTOME SIGNALING BY CSF3 G CSF	30	2.70e-01	0.116000	7.51e-01
REACTOME HDR THROUGH HOMOLOGOUS RECOMBINATION HRR	66	2.71e-01	-0.078300	7.51e-01
REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	69	2.72e-01	-0.076600	7.51e-01
REACTOME MET ACTIVATES PTK2 SIGNALING	30	2.72e-01	0.116000	7.51e-01
REACTOME HCMV LATE EVENTS	110	2.72e-01	-0.060700	7.51e-01
REACTOME REGULATION OF LIPID METABOLISM BY PPARALPHA	115	2.72e-01	-0.059300	7.51e-01
REACTOME ENDOGENOUS STEROLS	26	2.72e-01	0.124000	7.51e-01
REACTOME PKMTS METHYLATE HISTONE LYSINES	64	2.73e-01	-0.079200	7.53e-01
REACTOME MET INTERACTS WITH TNS PROTEINS	5	2.76e-01	-0.282000	7.57e-01
REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	11	2.76e-01	0.190000	7.57e-01
REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	45	2.78e-01	-0.093500	7.57e-01
REACTOME REGULATION OF PTEN LOCALIZATION	8	2.79e-01	0.221000	7.57e-01
REACTOME METABOLISM OF PORPHYRINS	26	2.79e-01	0.123000	7.57e-01
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	59	2.79e-01	-0.081500	7.57e-01
REACTOME SIALIC ACID METABOLISM	33	2.79e-01	-0.109000	7.57e-01
REACTOME NUCLEOTIDE BIOSYNTHESIS	14	2.79e-01	-0.167000	7.57e-01
REACTOME THYROXINE BIOSYNTHESIS	10	2.79e-01	0.198000	7.57e-01
REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	14	2.79e-01	-0.167000	7.57e-01
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	89	2.80e-01	-0.066300	7.57e-01
REACTOME NEUROFASCIN INTERACTIONS	6	2.82e-01	0.254000	7.60e-01
REACTOME COHESIN LOADING ONTO CHROMATIN	8	2.82e-01	-0.220000	7.60e-01
REACTOME P75NTR NEGATIVELY REGULATES CELL CYCLE VIA SC1	6	2.82e-01	-0.253000	7.60e-01
REACTOME AMPK INHIBITS CHREBP TRANSCRIPTIONAL ACTIVATION ACTIVITY	8	2.83e-01	-0.219000	7.60e-01
REACTOME O GLYCOSYLATION OF TSR DOMAIN CONTAINING PROTEINS	38	2.84e-01	0.100000	7.61e-01
REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	14	2.84e-01	-0.165000	7.61e-01
REACTOME NS1 MEDIATED EFFECTS ON HOST PATHWAYS	41	2.86e-01	-0.096400	7.62e-01
REACTOME MITOCHONDRIAL TRANSLATION	93	2.86e-01	0.064000	7.62e-01
REACTOME METABOLISM OF VITAMINS AND COFACTORS	185	2.86e-01	-0.045400	7.62e-01
REACTOME PLATELET HOMEOSTASIS	85	2.87e-01	-0.066900	7.62e-01
REACTOME BASE EXCISION REPAIR	87	2.87e-01	0.066100	7.62e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX1	229	2.89e-01	-0.040700	7.63e-01
REACTOME DEFECTIVE EXT2 CAUSES EXOSTOSES 2	12	2.89e-01	0.177000	7.63e-01
REACTOME MATURATION OF SARS COV 2 SPIKE PROTEIN	35	2.89e-01	-0.104000	7.63e-01
REACTOME INACTIVATION OF CSF3 G CSF SIGNALING	25	2.89e-01	0.122000	7.63e-01
REACTOME HYALURONAN BIOSYNTHESIS AND EXPORT	5	2.90e-01	0.273000	7.63e-01
REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	15	2.90e-01	-0.158000	7.63e-01
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	79	2.91e-01	0.068800	7.63e-01
REACTOME SIGNALING BY MRAS COMPLEX MUTANTS	7	2.92e-01	-0.230000	7.63e-01
REACTOME FERTILIZATION	26	2.92e-01	0.119000	7.63e-01
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	29	2.92e-01	-0.113000	7.63e-01
REACTOME SYNTHESIS OF 15 EICOSATETRAENOIC ACID DERIVATIVES	6	2.93e-01	-0.248000	7.64e-01
REACTOME CROSSLINKING OF COLLAGEN FIBRILS	16	2.93e-01	-0.152000	7.64e-01
REACTOME CYTOSOLIC TRNA AMINOACYLATION	22	2.94e-01	-0.129000	7.65e-01
REACTOME THE NLRP3 INFLAMMASOME	16	2.95e-01	-0.151000	7.67e-01
REACTOME SIGNALING BY PDGFRA TRANSMEMBRANE JUXTAMEMBRANE AND KINASE DOMAIN MUTANTS	12	2.96e-01	-0.174000	7.67e-01
REACTOME ENOS ACTIVATION	11	2.98e-01	0.181000	7.72e-01
REACTOME INTERFERON SIGNALING	193	2.99e-01	0.043300	7.73e-01
REACTOME INFLUENZA INFECTION	149	3.00e-01	0.049200	7.73e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF SATURATED FATTY ACIDS	11	3.01e-01	-0.180000	7.73e-01
REACTOME VISUAL PHOTOTRANSDUCTION	93	3.01e-01	-0.062100	7.73e-01
REACTOME MITOCHONDRIAL UNCOUPLING	5	3.01e-01	0.267000	7.73e-01
REACTOME AURKA ACTIVATION BY TPX2	69	3.02e-01	-0.071900	7.73e-01
REACTOME CA2 PATHWAY	62	3.02e-01	-0.075800	7.73e-01
REACTOME PROCESSING OF SMDT1	16	3.02e-01	-0.149000	7.73e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN CYTOCHROME C RELEASE	20	3.04e-01	-0.133000	7.75e-01
REACTOME SIGNALING BY FGFR IN DISEASE	62	3.04e-01	-0.075400	7.75e-01
REACTOME POLB DEPENDENT LONG PATCH BASE EXCISION REPAIR	8	3.05e-01	0.209000	7.75e-01
REACTOME ROLE OF SECOND MESSENGERS IN NETRIN 1 SIGNALING	9	3.05e-01	0.197000	7.75e-01
REACTOME SIGNALING BY LEPTIN	11	3.07e-01	-0.178000	7.79e-01
REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	91	3.08e-01	-0.061800	7.81e-01
REACTOME UPTAKE AND FUNCTION OF ANTHRAX TOXINS	11	3.09e-01	-0.177000	7.81e-01
REACTOME REGULATION BY C FLIP	11	3.09e-01	-0.177000	7.81e-01
REACTOME ACETYLCHOLINE REGULATES INSULIN SECRETION	10	3.11e-01	-0.185000	7.83e-01
REACTOME DEUBIQUITINATION	260	3.11e-01	-0.036500	7.83e-01
REACTOME TRAIL SIGNALING	8	3.11e-01	-0.207000	7.83e-01
REACTOME EPHA MEDIATED GROWTH CONE COLLAPSE	29	3.13e-01	-0.108000	7.87e-01
REACTOME TIE2 SIGNALING	18	3.14e-01	-0.137000	7.88e-01
REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	26	3.15e-01	-0.114000	7.88e-01
REACTOME RUNX1 AND FOXP3 CONTROL THE DEVELOPMENT OF REGULATORY T LYMPHOCYTES TREGS	9	3.16e-01	-0.193000	7.88e-01
REACTOME MITOCHONDRIAL PROTEIN IMPORT	58	3.17e-01	-0.076000	7.88e-01
REACTOME ZINC EFFLUX AND COMPARTMENTALIZATION BY THE SLC30 FAMILY	5	3.17e-01	0.259000	7.88e-01
REACTOME FRUCTOSE CATABOLISM	5	3.17e-01	-0.258000	7.88e-01
REACTOME ORC1 REMOVAL FROM CHROMATIN	70	3.17e-01	0.069100	7.88e-01
REACTOME SIGNALING BY KIT IN DISEASE	20	3.18e-01	-0.129000	7.89e-01
REACTOME RHOBTB1 GTPASE CYCLE	22	3.19e-01	-0.123000	7.89e-01
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE FGFR2	17	3.19e-01	0.140000	7.89e-01
REACTOME PRE NOTCH EXPRESSION AND PROCESSING	112	3.20e-01	-0.054400	7.91e-01
REACTOME DUAL INCISION IN TC NER	63	3.22e-01	-0.072100	7.94e-01
REACTOME OVARIAN TUMOR DOMAIN PROTEASES	36	3.23e-01	-0.095200	7.94e-01
REACTOME RHO GTPASES ACTIVATE PAKS	19	3.23e-01	-0.131000	7.94e-01
REACTOME DNA REPLICATION	178	3.25e-01	0.042800	7.96e-01
REACTOME SMALL INTERFERING RNA SIRNA BIOGENESIS	9	3.25e-01	-0.189000	7.96e-01
REACTOME DISEASES OF IMMUNE SYSTEM	29	3.26e-01	-0.105000	7.97e-01
REACTOME RHO GTPASES ACTIVATE IQGAPS	31	3.26e-01	-0.102000	7.97e-01
REACTOME ARACHIDONATE PRODUCTION FROM DAG	5	3.28e-01	-0.253000	8.00e-01
REACTOME IRON UPTAKE AND TRANSPORT	56	3.29e-01	-0.075400	8.02e-01
REACTOME GAP JUNCTION ASSEMBLY	36	3.30e-01	0.093700	8.02e-01
REACTOME SIGNALING BY MEMBRANE TETHERED FUSIONS OF PDGFRA OR PDGFRB	5	3.31e-01	0.251000	8.02e-01
REACTOME BBSOME MEDIATED CARGO TARGETING TO CILIUM	23	3.31e-01	0.117000	8.02e-01
REACTOME GROWTH HORMONE RECEPTOR SIGNALING	24	3.31e-01	-0.115000	8.02e-01
REACTOME SIGNALING BY ERBB2	50	3.35e-01	-0.078900	8.09e-01
REACTOME PRESYNAPTIC FUNCTION OF KAINATE RECEPTORS	21	3.35e-01	-0.122000	8.09e-01
REACTOME PROTEIN FOLDING	96	3.39e-01	-0.056500	8.13e-01
REACTOME RHO GTPASES ACTIVATE FORMINS	136	3.39e-01	-0.047400	8.13e-01
REACTOME BETA OXIDATION OF HEXANOYL COA TO BUTANOYL COA	5	3.41e-01	-0.246000	8.13e-01
REACTOME INTERLEUKIN 6 SIGNALING	11	3.41e-01	-0.166000	8.13e-01
REACTOME FRS MEDIATED FGFR4 SIGNALING	21	3.41e-01	0.120000	8.13e-01
REACTOME BETA OXIDATION OF LAUROYL COA TO DECANOYL COA COA	5	3.41e-01	-0.246000	8.13e-01
REACTOME CHK1 CHK2 CDS1 MEDIATED INACTIVATION OF CYCLIN B CDK1 COMPLEX	13	3.42e-01	-0.152000	8.13e-01
REACTOME IRAK1 RECRUITS IKK COMPLEX	12	3.42e-01	0.158000	8.13e-01
REACTOME BETA DEFENSINS	27	3.42e-01	0.106000	8.13e-01
REACTOME INTRAFLAGELLAR TRANSPORT	50	3.43e-01	-0.077500	8.13e-01
REACTOME RESOLUTION OF D LOOP STRUCTURES THROUGH SYNTHESIS DEPENDENT STRAND ANNEALING SDSA	27	3.43e-01	-0.105000	8.13e-01
REACTOME SCAVENGING BY CLASS F RECEPTORS	6	3.43e-01	-0.223000	8.13e-01
REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	45	3.44e-01	-0.081600	8.13e-01
REACTOME SENSORY PERCEPTION OF TASTE	47	3.44e-01	-0.079800	8.13e-01
REACTOME UCH PROTEINASES	99	3.45e-01	0.054900	8.13e-01
REACTOME EGFR TRANSACTIVATION BY GASTRIN	9	3.45e-01	-0.182000	8.13e-01
REACTOME SYNTHESIS OF 5 EICOSATETRAENOIC ACIDS	9	3.45e-01	-0.182000	8.13e-01
REACTOME TRP CHANNELS	27	3.46e-01	-0.105000	8.13e-01
REACTOME NEGATIVE REGULATION OF ACTIVITY OF TFAP2 AP 2 FAMILY TRANSCRIPTION FACTORS	10	3.47e-01	-0.172000	8.13e-01
REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	9	3.47e-01	-0.181000	8.13e-01
REACTOME VASOPRESSIN REGULATES RENAL WATER HOMEOSTASIS VIA AQUAPORINS	42	3.48e-01	-0.083700	8.13e-01
REACTOME EGFR DOWNREGULATION	30	3.48e-01	-0.099000	8.13e-01
REACTOME KEAP1 NFE2L2 PATHWAY	104	3.48e-01	-0.053300	8.13e-01
REACTOME PRE NOTCH PROCESSING IN THE ENDOPLASMIC RETICULUM	6	3.51e-01	-0.220000	8.15e-01
REACTOME FGFR1B LIGAND BINDING AND ACTIVATION	6	3.51e-01	-0.220000	8.15e-01
REACTOME CROSS PRESENTATION OF PARTICULATE EXOGENOUS ANTIGENS PHAGOSOMES	6	3.52e-01	-0.219000	8.15e-01
REACTOME VITAMIN B2 RIBOFLAVIN METABOLISM	7	3.52e-01	-0.203000	8.15e-01
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	688	3.52e-01	0.020800	8.15e-01
REACTOME FCERI MEDIATED NF KB ACTIVATION	78	3.52e-01	0.060900	8.15e-01
REACTOME FATTY ACIDS BOUND TO GPR40 FFAR1 REGULATE INSULIN SECRETION	8	3.53e-01	-0.190000	8.15e-01
REACTOME INACTIVATION OF CDC42 AND RAC1	8	3.54e-01	-0.189000	8.16e-01
REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	16	3.55e-01	0.133000	8.16e-01
REACTOME SUMOYLATION OF CHROMATIN ORGANIZATION PROTEINS	68	3.56e-01	0.064800	8.16e-01
REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	14	3.56e-01	-0.143000	8.16e-01
REACTOME SEROTONIN NEUROTRANSMITTER RELEASE CYCLE	17	3.56e-01	0.129000	8.16e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	14	3.56e-01	-0.142000	8.16e-01
REACTOME ASPARTATE AND ASPARAGINE METABOLISM	11	3.57e-01	0.160000	8.16e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH FRS2 AND FRS3	11	3.57e-01	-0.160000	8.16e-01
REACTOME SUMO IS CONJUGATED TO E1 UBA2 SAE1	5	3.58e-01	0.237000	8.18e-01
REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	57	3.59e-01	-0.070300	8.18e-01
REACTOME PROTEIN REPAIR	6	3.59e-01	-0.216000	8.18e-01
REACTOME SCAVENGING OF HEME FROM PLASMA	13	3.61e-01	0.146000	8.19e-01
REACTOME NEF MEDIATED CD4 DOWN REGULATION	9	3.61e-01	-0.176000	8.19e-01
REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	10	3.62e-01	-0.167000	8.19e-01
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	106	3.62e-01	0.051300	8.19e-01
REACTOME HDL REMODELING	10	3.63e-01	0.166000	8.19e-01
REACTOME CONSTITUTIVE SIGNALING BY AKT1 E17K IN CANCER	25	3.64e-01	-0.105000	8.19e-01
REACTOME CIPROFLOXACIN ADME	5	3.64e-01	0.234000	8.19e-01
REACTOME SIGNALING BY GPCR	673	3.64e-01	-0.020500	8.19e-01
REACTOME COMMON PATHWAY OF FIBRIN CLOT FORMATION	21	3.65e-01	0.114000	8.19e-01
REACTOME COPI INDEPENDENT GOLGI TO ER RETROGRADE TRAFFIC	52	3.66e-01	-0.072500	8.19e-01
REACTOME COSTIMULATION BY THE CD28 FAMILY	64	3.67e-01	0.065200	8.19e-01
REACTOME COENZYME A BIOSYNTHESIS	8	3.68e-01	0.184000	8.19e-01
REACTOME ACTIVATION OF RAS IN B CELLS	5	3.68e-01	-0.233000	8.19e-01
REACTOME HIV LIFE CYCLE	145	3.69e-01	-0.043300	8.19e-01
REACTOME ABACAVIR ADME	9	3.69e-01	0.173000	8.19e-01
REACTOME DEFECTIVE CHSY1 CAUSES TPBS	7	3.69e-01	0.196000	8.19e-01
REACTOME KINESINS	59	3.70e-01	-0.067500	8.19e-01
REACTOME SIRT1 NEGATIVELY REGULATES RRNA EXPRESSION	60	3.70e-01	0.066900	8.19e-01
REACTOME SYNTHESIS OF PIPS AT THE ER MEMBRANE	5	3.70e-01	-0.231000	8.19e-01
REACTOME DEFECTIVE B4GALT1 CAUSES B4GALT1 CDG CDG 2D	8	3.71e-01	0.183000	8.19e-01
REACTOME RHOD GTPASE CYCLE	49	3.71e-01	-0.073800	8.19e-01
REACTOME CD28 CO STIMULATION	32	3.71e-01	-0.091300	8.19e-01
REACTOME LIPID PARTICLE ORGANIZATION	6	3.72e-01	-0.211000	8.19e-01
REACTOME ROLE OF LAT2 NTAL LAB ON CALCIUM MOBILIZATION	16	3.72e-01	-0.129000	8.19e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 12	22	3.72e-01	-0.110000	8.20e-01
REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	20	3.73e-01	0.115000	8.21e-01
REACTOME PROPIONYL COA CATABOLISM	5	3.76e-01	-0.229000	8.25e-01
REACTOME HOST INTERACTIONS OF HIV FACTORS	127	3.78e-01	0.045300	8.27e-01
REACTOME PROLACTIN RECEPTOR SIGNALING	15	3.78e-01	-0.131000	8.27e-01
REACTOME DEGRADATION OF CYSTEINE AND HOMOCYSTEINE	15	3.78e-01	-0.131000	8.27e-01
REACTOME EPIGENETIC REGULATION OF GENE EXPRESSION	138	3.79e-01	-0.043300	8.27e-01
REACTOME HIV TRANSCRIPTION ELONGATION	42	3.79e-01	-0.078400	8.27e-01
REACTOME BETA CATENIN PHOSPHORYLATION CASCADE	16	3.83e-01	-0.126000	8.32e-01
REACTOME INHIBITION OF DNA RECOMBINATION AT TELOMERE	63	3.83e-01	0.063500	8.32e-01
REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	50	3.83e-01	-0.071200	8.32e-01
REACTOME TRANSPORT OF MATURE MRNAS DERIVED FROM INTRONLESS TRANSCRIPTS	43	3.84e-01	-0.076700	8.32e-01
REACTOME COMPLEX I BIOGENESIS	49	3.84e-01	-0.071900	8.32e-01
REACTOME ESTROGEN BIOSYNTHESIS	6	3.85e-01	0.205000	8.32e-01
REACTOME LOSS OF FUNCTION OF MECP2 IN RETT SYNDROME	11	3.86e-01	-0.151000	8.34e-01
REACTOME PROTON COUPLED MONOCARBOXYLATE TRANSPORT	6	3.87e-01	-0.204000	8.34e-01
REACTOME NOTCH3 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	24	3.88e-01	-0.102000	8.35e-01
REACTOME SODIUM PROTON EXCHANGERS	7	3.89e-01	-0.188000	8.36e-01
REACTOME CREB3 FACTORS ACTIVATE GENES	8	3.89e-01	0.176000	8.36e-01
REACTOME CONSTITUTIVE SIGNALING BY LIGAND RESPONSIVE EGFR CANCER VARIANTS	19	3.90e-01	0.114000	8.36e-01
REACTOME WNT MEDIATED ACTIVATION OF DVL	8	3.92e-01	-0.175000	8.40e-01
REACTOME DNA DOUBLE STRAND BREAK RESPONSE	74	3.93e-01	0.057500	8.40e-01
REACTOME STAT3 NUCLEAR EVENTS DOWNSTREAM OF ALK SIGNALING	9	3.93e-01	0.164000	8.41e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH PI3K	6	3.95e-01	-0.200000	8.42e-01
REACTOME HCMV EARLY EVENTS	128	3.96e-01	-0.043500	8.42e-01
REACTOME HSF1 DEPENDENT TRANSACTIVATION	37	3.96e-01	0.080600	8.42e-01
REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	23	3.96e-01	0.102000	8.42e-01
REACTOME ZINC INFLUX INTO CELLS BY THE SLC39 GENE FAMILY	10	3.96e-01	-0.155000	8.42e-01
REACTOME PLATELET AGGREGATION PLUG FORMATION	39	3.97e-01	0.078300	8.42e-01
REACTOME ARMS MEDIATED ACTIVATION	7	3.98e-01	-0.185000	8.42e-01
REACTOME HIGHLY SODIUM PERMEABLE POSTSYNAPTIC ACETYLCHOLINE NICOTINIC RECEPTORS	7	3.98e-01	0.184000	8.42e-01
REACTOME G ALPHA 12 13 SIGNALLING EVENTS	74	3.99e-01	-0.056800	8.42e-01
REACTOME RRNA PROCESSING IN THE MITOCHONDRION	9	3.99e-01	-0.162000	8.43e-01
REACTOME ATTENUATION PHASE	27	4.01e-01	0.093300	8.44e-01
REACTOME CAMK IV MEDIATED PHOSPHORYLATION OF CREB	10	4.01e-01	-0.153000	8.44e-01
REACTOME NTRK2 ACTIVATES RAC1	5	4.02e-01	-0.217000	8.44e-01
REACTOME SIGNAL AMPLIFICATION	33	4.02e-01	-0.084300	8.44e-01
REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	21	4.03e-01	0.105000	8.45e-01
REACTOME NEGATIVE REGULATORS OF DDX58 IFIH1 SIGNALING	34	4.06e-01	0.082400	8.47e-01
REACTOME PI5P REGULATES TP53 ACETYLATION	9	4.06e-01	-0.160000	8.47e-01
REACTOME LOSS OF MECP2 BINDING ABILITY TO THE NCOR SMRT COMPLEX	5	4.06e-01	-0.215000	8.47e-01
REACTOME DERMATAN SULFATE BIOSYNTHESIS	10	4.06e-01	0.152000	8.47e-01
REACTOME SIGNALING BY NOTCH1 T 7 9 NOTCH1 M1580 K2555 TRANSLOCATION MUTANT	7	4.07e-01	-0.181000	8.47e-01
REACTOME DNA DAMAGE RECOGNITION IN GG NER	36	4.08e-01	-0.079700	8.47e-01
REACTOME ACTIVATION OF SMO	18	4.09e-01	-0.113000	8.47e-01
REACTOME SARS COV 2 HOST INTERACTIONS	191	4.09e-01	0.034600	8.47e-01
REACTOME CELLULAR RESPONSE TO STARVATION	147	4.09e-01	0.039400	8.47e-01
REACTOME SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP	104	4.10e-01	0.046800	8.47e-01
REACTOME DAP12 SIGNALING	27	4.10e-01	0.091600	8.47e-01
REACTOME SHC MEDIATED CASCADE FGFR3	17	4.10e-01	0.115000	8.47e-01
REACTOME ADP SIGNALLING THROUGH P2Y PURINOCEPTOR 1	25	4.12e-01	-0.094800	8.49e-01
REACTOME SIGNALING BY NTRK2 TRKB	25	4.12e-01	-0.094800	8.49e-01
REACTOME ANCHORING FIBRIL FORMATION	13	4.14e-01	0.131000	8.51e-01
REACTOME INTERLEUKIN 18 SIGNALING	8	4.16e-01	-0.166000	8.54e-01
REACTOME MEIOTIC SYNAPSIS	73	4.16e-01	0.055100	8.54e-01
REACTOME PYROPTOSIS	27	4.18e-01	-0.090100	8.56e-01
REACTOME ASSEMBLY OF THE ORC COMPLEX AT THE ORIGIN OF REPLICATION	62	4.19e-01	0.059400	8.56e-01
REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	29	4.19e-01	-0.086700	8.56e-01
REACTOME REGULATION OF NPAS4 GENE TRANSCRIPTION	5	4.19e-01	0.209000	8.56e-01
REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	19	4.20e-01	-0.107000	8.57e-01
REACTOME SIGNALING BY NTRK3 TRKC	17	4.20e-01	-0.113000	8.57e-01
REACTOME NICOTINAMIDE SALVAGING	19	4.23e-01	0.106000	8.60e-01
REACTOME RESOLUTION OF SISTER CHROMATID COHESION	120	4.23e-01	-0.042300	8.60e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF GENES INVOLVED IN G2 CELL CYCLE ARREST	18	4.24e-01	-0.109000	8.60e-01
REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	20	4.24e-01	-0.103000	8.60e-01
REACTOME ALPHA DEFENSINS	6	4.25e-01	-0.188000	8.60e-01
REACTOME E3 UBIQUITIN LIGASES UBIQUITINATE TARGET PROTEINS	58	4.27e-01	0.060300	8.60e-01
REACTOME MECP2 REGULATES TRANSCRIPTION OF NEURONAL LIGANDS	7	4.28e-01	-0.173000	8.60e-01
REACTOME GLUCOSE METABOLISM	90	4.28e-01	-0.048300	8.60e-01
REACTOME PHASE 3 RAPID REPOLARISATION	8	4.28e-01	-0.162000	8.60e-01
REACTOME INSULIN PROCESSING	24	4.29e-01	-0.093400	8.60e-01
REACTOME DEX H BOX HELICASES ACTIVATE TYPE I IFN AND INFLAMMATORY CYTOKINES PRODUCTION	7	4.29e-01	0.173000	8.60e-01
REACTOME SIGNALING BY WNT IN CANCER	32	4.30e-01	-0.080600	8.60e-01
REACTOME GAB1 SIGNALOSOME	17	4.30e-01	-0.111000	8.60e-01
REACTOME NEGATIVE REGULATION OF FGFR3 SIGNALING	28	4.30e-01	0.086100	8.60e-01
REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	17	4.30e-01	0.111000	8.60e-01
REACTOME ACTIVATED NTRK3 SIGNALS THROUGH RAS	8	4.31e-01	-0.161000	8.60e-01
REACTOME MET ACTIVATES RAS SIGNALING	11	4.32e-01	-0.137000	8.61e-01
REACTOME ACTIVATION OF NIMA KINASES NEK9 NEK6 NEK7	7	4.33e-01	0.171000	8.61e-01
REACTOME PYRIMIDINE SALVAGE	10	4.34e-01	-0.143000	8.61e-01
REACTOME SIGNALING BY FGFR4 IN DISEASE	11	4.34e-01	-0.136000	8.61e-01
REACTOME CELL CELL JUNCTION ORGANIZATION	64	4.34e-01	0.056500	8.61e-01
REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	296	4.35e-01	-0.026400	8.61e-01
REACTOME CELLULAR HEXOSE TRANSPORT	21	4.36e-01	-0.098200	8.61e-01
REACTOME PI3K AKT SIGNALING IN CANCER	103	4.36e-01	0.044400	8.61e-01
REACTOME EPHRIN SIGNALING	17	4.37e-01	-0.109000	8.61e-01
REACTOME SIGNALING BY ALK IN CANCER	53	4.37e-01	-0.061700	8.61e-01
REACTOME AFLATOXIN ACTIVATION AND DETOXIFICATION	19	4.38e-01	-0.103000	8.61e-01
REACTOME RUNX3 REGULATES CDKN1A TRANSCRIPTION	7	4.38e-01	-0.169000	8.61e-01
REACTOME PEPTIDE LIGAND BINDING RECEPTORS	188	4.39e-01	0.032800	8.61e-01
REACTOME MAPK FAMILY SIGNALING CASCADES	314	4.39e-01	0.025400	8.61e-01
REACTOME G2 M DNA REPLICATION CHECKPOINT	5	4.39e-01	0.200000	8.61e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO GLUCONEOGENESIS	5	4.39e-01	-0.200000	8.61e-01
REACTOME GASTRULATION	49	4.40e-01	-0.063800	8.61e-01
REACTOME LGI ADAM INTERACTIONS	14	4.41e-01	0.119000	8.62e-01
REACTOME CARDIAC CONDUCTION	125	4.42e-01	0.039800	8.63e-01
REACTOME ONCOGENE INDUCED SENESCENCE	35	4.45e-01	0.074700	8.64e-01
REACTOME CYCLIN A CDK2 ASSOCIATED EVENTS AT S PHASE ENTRY	84	4.45e-01	0.048200	8.64e-01
REACTOME SIGNALING BY NOTCH1 HD DOMAIN MUTANTS IN CANCER	15	4.45e-01	0.114000	8.64e-01
REACTOME TELOMERE C STRAND SYNTHESIS INITIATION	12	4.45e-01	0.127000	8.64e-01
REACTOME G ALPHA I SIGNALLING EVENTS	304	4.46e-01	-0.025400	8.64e-01
REACTOME GAP JUNCTION DEGRADATION	12	4.47e-01	-0.127000	8.64e-01
REACTOME DNA DAMAGE BYPASS	47	4.48e-01	-0.063900	8.64e-01
REACTOME PROTEIN UBIQUITINATION	76	4.49e-01	0.050200	8.64e-01
REACTOME LOSS OF FUNCTION OF SMAD2 3 IN CANCER	7	4.51e-01	-0.165000	8.64e-01
REACTOME TELOMERE EXTENSION BY TELOMERASE	22	4.51e-01	-0.092900	8.64e-01
REACTOME FORMATION OF PARAXIAL MESODERM	22	4.51e-01	-0.092800	8.64e-01
REACTOME HDR THROUGH MMEJ ALT NHEJ	12	4.51e-01	-0.126000	8.64e-01
REACTOME PEROXISOMAL PROTEIN IMPORT	62	4.52e-01	0.055300	8.64e-01
REACTOME GPVI MEDIATED ACTIVATION CASCADE	35	4.52e-01	-0.073500	8.64e-01
REACTOME DEFECTIVE CHST14 CAUSES EDS MUSCULOCONTRACTURAL TYPE	7	4.52e-01	0.164000	8.64e-01
REACTOME GOLGI CISTERNAE PERICENTRIOLAR STACK REORGANIZATION	14	4.52e-01	-0.116000	8.64e-01
REACTOME REGULATED PROTEOLYSIS OF P75NTR	11	4.52e-01	-0.131000	8.64e-01
REACTOME ACTIVATION OF PUMA AND TRANSLOCATION TO MITOCHONDRIA	9	4.52e-01	-0.145000	8.64e-01
REACTOME INITIATION OF NUCLEAR ENVELOPE NE REFORMATION	18	4.52e-01	-0.102000	8.64e-01
REACTOME RNA POLYMERASE I PROMOTER ESCAPE	83	4.53e-01	0.047600	8.64e-01
REACTOME RUNX2 REGULATES CHONDROCYTE MATURATION	5	4.56e-01	-0.193000	8.68e-01
REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	17	4.56e-01	0.104000	8.68e-01
REACTOME FREE FATTY ACIDS REGULATE INSULIN SECRETION	10	4.57e-01	-0.136000	8.68e-01
REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	15	4.57e-01	-0.111000	8.68e-01
REACTOME INTERLEUKIN 4 AND INTERLEUKIN 13 SIGNALING	103	4.58e-01	0.042300	8.68e-01
REACTOME DISINHIBITION OF SNARE FORMATION	5	4.59e-01	0.191000	8.69e-01
REACTOME LYSINE CATABOLISM	12	4.59e-01	0.123000	8.69e-01
REACTOME CARGO TRAFFICKING TO THE PERICILIARY MEMBRANE	49	4.60e-01	-0.061100	8.69e-01
REACTOME RRNA MODIFICATION IN THE MITOCHONDRION	6	4.60e-01	-0.174000	8.69e-01
REACTOME METAL ION SLC TRANSPORTERS	23	4.61e-01	-0.088800	8.69e-01
REACTOME THE CITRIC ACID TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	159	4.62e-01	-0.033800	8.69e-01
REACTOME SARS COV 2 ACTIVATES MODULATES INNATE AND ADAPTIVE IMMUNE RESPONSES	118	4.62e-01	0.039200	8.69e-01
REACTOME TFAP2A ACTS AS A TRANSCRIPTIONAL REPRESSOR DURING RETINOIC ACID INDUCED CELL DIFFERENTIATION	5	4.63e-01	0.190000	8.69e-01
REACTOME SIGNALING BY CYTOSOLIC FGFR1 FUSION MUTANTS	18	4.64e-01	-0.099600	8.71e-01
REACTOME SIGNALING BY NOTCH4	80	4.66e-01	0.047200	8.71e-01
REACTOME DNA REPLICATION INITIATION	7	4.66e-01	-0.159000	8.71e-01
REACTOME RNA POLYMERASE II PRE TRANSCRIPTION EVENTS	77	4.66e-01	-0.048000	8.71e-01
REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION OF UNSATURATED FATTY ACIDS	6	4.66e-01	-0.172000	8.71e-01
REACTOME NOTCH2 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	11	4.68e-01	-0.126000	8.71e-01
REACTOME STAT5 ACTIVATION	7	4.68e-01	0.158000	8.71e-01
REACTOME SIGNALING BY ALK	26	4.69e-01	0.082100	8.71e-01
REACTOME REGULATION OF IFNA IFNB SIGNALING	23	4.69e-01	0.087300	8.71e-01
REACTOME RUNX1 REGULATES ESTROGEN RECEPTOR MEDIATED TRANSCRIPTION	6	4.69e-01	-0.171000	8.71e-01
REACTOME ION TRANSPORT BY P TYPE ATPASES	51	4.71e-01	-0.058400	8.71e-01
REACTOME ESTABLISHMENT OF SISTER CHROMATID COHESION	9	4.71e-01	-0.139000	8.71e-01
REACTOME SERINE BIOSYNTHESIS	9	4.73e-01	0.138000	8.71e-01
REACTOME B WICH COMPLEX POSITIVELY REGULATES RRNA EXPRESSION	84	4.73e-01	0.045300	8.71e-01
REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	14	4.74e-01	0.110000	8.71e-01
REACTOME SMOOTH MUSCLE CONTRACTION	43	4.74e-01	-0.063100	8.71e-01
REACTOME SUMOYLATION OF TRANSCRIPTION FACTORS	20	4.75e-01	-0.092400	8.71e-01
REACTOME POST TRANSCRIPTIONAL SILENCING BY SMALL RNAS	7	4.75e-01	-0.156000	8.71e-01
REACTOME JOSEPHIN DOMAIN DUBS	11	4.75e-01	0.124000	8.71e-01
REACTOME HOMOLOGY DIRECTED REPAIR	132	4.76e-01	-0.036000	8.71e-01
REACTOME PCP CE PATHWAY	91	4.76e-01	0.043300	8.71e-01
REACTOME MITOTIC TELOPHASE CYTOKINESIS	11	4.76e-01	-0.124000	8.71e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD4	15	4.76e-01	-0.106000	8.71e-01
REACTOME NF KB IS ACTIVATED AND SIGNALS SURVIVAL	12	4.76e-01	0.119000	8.71e-01
REACTOME NOTCH3 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	25	4.77e-01	0.082100	8.72e-01
REACTOME RUNX1 REGULATES EXPRESSION OF COMPONENTS OF TIGHT JUNCTIONS	5	4.80e-01	-0.182000	8.75e-01
REACTOME MET PROMOTES CELL MOTILITY	41	4.81e-01	0.063600	8.75e-01
REACTOME COBALAMIN CBL METABOLISM	7	4.82e-01	-0.154000	8.75e-01
REACTOME CYTOCHROME C MEDIATED APOPTOTIC RESPONSE	12	4.82e-01	-0.117000	8.75e-01
REACTOME UNFOLDED PROTEIN RESPONSE UPR	88	4.82e-01	-0.043400	8.75e-01
REACTOME METABOLISM OF FOLATE AND PTERINES	17	4.82e-01	-0.098500	8.75e-01
REACTOME TNFS BIND THEIR PHYSIOLOGICAL RECEPTORS	26	4.83e-01	0.079500	8.75e-01
REACTOME ERYTHROPOIETIN ACTIVATES PHOSPHOLIPASE C GAMMA PLCG	7	4.84e-01	-0.153000	8.75e-01
REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	13	4.85e-01	-0.112000	8.75e-01
REACTOME FORMATION OF LATERAL PLATE MESODERM	5	4.86e-01	-0.180000	8.75e-01
REACTOME REGULATION OF NPAS4 MRNA TRANSLATION	9	4.86e-01	-0.134000	8.75e-01
REACTOME RHO GTPASES ACTIVATE ROCKS	19	4.87e-01	-0.092200	8.75e-01
REACTOME KERATAN SULFATE DEGRADATION	13	4.87e-01	0.111000	8.75e-01
REACTOME HIV ELONGATION ARREST AND RECOVERY	33	4.89e-01	-0.069600	8.75e-01
REACTOME FIBRONECTIN MATRIX FORMATION	6	4.89e-01	-0.163000	8.75e-01
REACTOME NUCLEAR EVENTS MEDIATED BY NFE2L2	77	4.89e-01	0.045600	8.75e-01
REACTOME CREB1 PHOSPHORYLATION THROUGH THE ACTIVATION OF ADENYLATE CYCLASE	11	4.89e-01	-0.120000	8.75e-01
REACTOME G BETA GAMMA SIGNALLING THROUGH CDC42	19	4.90e-01	-0.091600	8.75e-01
REACTOME INTESTINAL ABSORPTION	5	4.91e-01	0.178000	8.75e-01
REACTOME RHO GTPASES ACTIVATE CIT	19	4.91e-01	-0.091300	8.75e-01
REACTOME DISEASES ASSOCIATED WITH GLYCOSAMINOGLYCAN METABOLISM	38	4.91e-01	0.064600	8.75e-01
REACTOME CRISTAE FORMATION	27	4.91e-01	-0.076500	8.75e-01
REACTOME SYNTHESIS OF DNA	119	4.92e-01	0.036500	8.75e-01
REACTOME INTERLEUKIN 1 SIGNALING	110	4.92e-01	0.037900	8.75e-01
REACTOME MET RECEPTOR RECYCLING	10	4.93e-01	-0.125000	8.75e-01
REACTOME EFFECTS OF PIP2 HYDROLYSIS	26	4.93e-01	-0.077600	8.75e-01
REACTOME SIGNALING BY NODAL	20	4.94e-01	-0.088400	8.75e-01
REACTOME METHIONINE SALVAGE PATHWAY	6	4.94e-01	-0.161000	8.75e-01
REACTOME REMOVAL OF AMINOTERMINAL PROPEPTIDES FROM GAMMA CARBOXYLATED PROTEINS	8	4.97e-01	-0.139000	8.76e-01
REACTOME CELLULAR RESPONSES TO STIMULI	779	4.98e-01	-0.014300	8.76e-01
REACTOME SARS COV 1 INFECTION	136	4.98e-01	-0.033700	8.76e-01
REACTOME DISORDERS OF TRANSMEMBRANE TRANSPORTERS	170	4.98e-01	0.030100	8.76e-01
REACTOME CELL CYCLE CHECKPOINTS	284	4.99e-01	0.023300	8.76e-01
REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	15	4.99e-01	0.101000	8.76e-01
REACTOME HYDROLYSIS OF LPC	9	5.00e-01	-0.130000	8.76e-01
REACTOME TYPE I HEMIDESMOSOME ASSEMBLY	11	5.00e-01	0.117000	8.76e-01
REACTOME PTK6 REGULATES CELL CYCLE	6	5.00e-01	-0.159000	8.76e-01
REACTOME MUSCLE CONTRACTION	197	5.01e-01	0.027800	8.76e-01
REACTOME SARS COV 1 ACTIVATES MODULATES INNATE IMMUNE RESPONSES	39	5.03e-01	0.062000	8.76e-01
REACTOME CELLULAR RESPONSE TO HEAT STRESS	99	5.03e-01	0.039000	8.76e-01
REACTOME ACYL CHAIN REMODELLING OF PI	17	5.03e-01	0.093800	8.76e-01
REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	44	5.03e-01	-0.058300	8.76e-01
REACTOME NETRIN 1 SIGNALING	49	5.04e-01	0.055200	8.76e-01
REACTOME RUNX3 REGULATES P14 ARF	10	5.04e-01	-0.122000	8.76e-01
REACTOME GLUTATHIONE CONJUGATION	33	5.04e-01	-0.067200	8.76e-01
REACTOME ACTIVATED PKN1 STIMULATES TRANSCRIPTION OF AR ANDROGEN RECEPTOR REGULATED GENES KLK2 AND KLK3	59	5.05e-01	0.050200	8.76e-01
REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	22	5.05e-01	-0.082100	8.76e-01
REACTOME G2 PHASE	5	5.05e-01	-0.172000	8.76e-01
REACTOME DRUG MEDIATED INHIBITION OF CDK4 CDK6 ACTIVITY	5	5.07e-01	0.172000	8.77e-01
REACTOME FANCONI ANEMIA PATHWAY	35	5.07e-01	0.064900	8.77e-01
REACTOME MISCELLANEOUS TRANSPORT AND BINDING EVENTS	24	5.09e-01	-0.077900	8.79e-01
REACTOME SIGNALING BY SCF KIT	42	5.10e-01	-0.058800	8.79e-01
REACTOME G ALPHA Z SIGNALLING EVENTS	48	5.10e-01	-0.055000	8.79e-01
REACTOME STIMULI SENSING CHANNELS	100	5.11e-01	0.038000	8.80e-01
REACTOME HDACS DEACETYLATE HISTONES	85	5.12e-01	-0.041100	8.81e-01
REACTOME SYNDECAN INTERACTIONS	26	5.13e-01	0.074200	8.81e-01
REACTOME CALCINEURIN ACTIVATES NFAT	9	5.13e-01	-0.126000	8.81e-01
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	255	5.14e-01	-0.023800	8.81e-01
REACTOME REGULATION OF PTEN MRNA TRANSLATION	9	5.14e-01	-0.126000	8.81e-01
REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	12	5.15e-01	0.108000	8.81e-01
REACTOME PASSIVE TRANSPORT BY AQUAPORINS	13	5.15e-01	-0.104000	8.81e-01
REACTOME CYCLIN A B1 B2 ASSOCIATED EVENTS DURING G2 M TRANSITION	24	5.18e-01	-0.076300	8.82e-01
REACTOME MRNA CAPPING	28	5.18e-01	-0.070600	8.82e-01
REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	31	5.19e-01	-0.066900	8.82e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION	41	5.19e-01	-0.058200	8.82e-01
REACTOME SIGNALING BY WNT	318	5.19e-01	-0.021000	8.82e-01
REACTOME LRR FLII INTERACTING PROTEIN 1 LRRFIP1 ACTIVATES TYPE I IFN PRODUCTION	5	5.19e-01	-0.166000	8.82e-01
REACTOME REGULATION OF PTEN STABILITY AND ACTIVITY	67	5.19e-01	0.045500	8.82e-01
REACTOME SUMOYLATION OF UBIQUITINYLATION PROTEINS	39	5.21e-01	-0.059400	8.83e-01
REACTOME FASL CD95L SIGNALING	5	5.21e-01	-0.166000	8.83e-01
REACTOME INTRACELLULAR SIGNALING BY SECOND MESSENGERS	299	5.22e-01	-0.021500	8.83e-01
REACTOME NEDDYLATION	235	5.23e-01	-0.024200	8.85e-01
REACTOME RND1 GTPASE CYCLE	41	5.24e-01	0.057500	8.85e-01
REACTOME DISEASES OF METABOLISM	237	5.25e-01	-0.024000	8.85e-01
REACTOME NETRIN MEDIATED REPULSION SIGNALS	8	5.25e-01	-0.130000	8.85e-01
REACTOME PI3K EVENTS IN ERBB2 SIGNALING	16	5.26e-01	0.091500	8.85e-01
REACTOME PROCESSING AND ACTIVATION OF SUMO	10	5.27e-01	0.116000	8.85e-01
REACTOME INLA MEDIATED ENTRY OF LISTERIA MONOCYTOGENES INTO HOST CELLS	9	5.27e-01	0.122000	8.85e-01
REACTOME FLT3 SIGNALING	38	5.27e-01	0.059300	8.85e-01
REACTOME COPI MEDIATED ANTEROGRADE TRANSPORT	101	5.29e-01	-0.036300	8.86e-01
REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	111	5.29e-01	0.034600	8.86e-01
REACTOME ACYL CHAIN REMODELING OF CL	5	5.30e-01	-0.162000	8.87e-01
REACTOME VIRAL MESSENGER RNA SYNTHESIS	44	5.30e-01	-0.054700	8.87e-01
REACTOME AGGREPHAGY	42	5.31e-01	0.055900	8.87e-01
REACTOME CARGO RECOGNITION FOR CLATHRIN MEDIATED ENDOCYTOSIS	100	5.32e-01	-0.036200	8.87e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR3	24	5.33e-01	0.073500	8.88e-01
REACTOME SIGNALING BY INTERLEUKINS	444	5.33e-01	0.017200	8.88e-01
REACTOME ACTIVATION OF RAC1	12	5.35e-01	-0.103000	8.89e-01
REACTOME TRAF6 MEDIATED NF KB ACTIVATION	24	5.36e-01	-0.073100	8.89e-01
REACTOME TYSND1 CLEAVES PEROXISOMAL PROTEINS	7	5.36e-01	0.135000	8.89e-01
REACTOME HDL CLEARANCE	5	5.38e-01	-0.159000	8.92e-01
REACTOME SHC1 EVENTS IN ERBB2 SIGNALING	22	5.40e-01	-0.075400	8.95e-01
REACTOME GABA RECEPTOR ACTIVATION	57	5.42e-01	-0.046700	8.96e-01
REACTOME CHROMOSOME MAINTENANCE	130	5.44e-01	0.030800	8.96e-01
REACTOME ACTIVATION OF THE AP 1 FAMILY OF TRANSCRIPTION FACTORS	10	5.44e-01	-0.111000	8.96e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF SEVERAL ADDITIONAL CELL DEATH GENES WHOSE SPECIFIC ROLES IN P53 DEPENDENT APOPTOSIS REMAIN UNCERTAIN	13	5.44e-01	-0.097200	8.96e-01
REACTOME PI 3K CASCADE FGFR2	22	5.46e-01	0.074400	8.96e-01
REACTOME NR1H3 NR1H2 REGULATE GENE EXPRESSION LINKED TO CHOLESTEROL TRANSPORT AND EFFLUX	36	5.46e-01	-0.058100	8.96e-01
REACTOME CD163 MEDIATING AN ANTI INFLAMMATORY RESPONSE	9	5.47e-01	-0.116000	8.96e-01
REACTOME DISEASES OF PROGRAMMED CELL DEATH	96	5.47e-01	-0.035600	8.96e-01
REACTOME REGULATION OF SIGNALING BY NODAL	9	5.48e-01	0.116000	8.96e-01
REACTOME ECM PROTEOGLYCANS	73	5.48e-01	0.040700	8.96e-01
REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	53	5.49e-01	0.047600	8.96e-01
REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	23	5.49e-01	-0.072200	8.96e-01
REACTOME ASSEMBLY OF COLLAGEN FIBRILS AND OTHER MULTIMERIC STRUCTURES	59	5.49e-01	0.045100	8.96e-01
REACTOME CELL JUNCTION ORGANIZATION	89	5.49e-01	0.036800	8.96e-01
REACTOME MET RECEPTOR ACTIVATION	6	5.49e-01	0.141000	8.96e-01
REACTOME TYROSINE CATABOLISM	5	5.49e-01	-0.155000	8.96e-01
REACTOME DEACTIVATION OF THE BETA CATENIN TRANSACTIVATING COMPLEX	39	5.50e-01	0.055300	8.97e-01
REACTOME SYNTHESIS OF PROSTAGLANDINS PG AND THROMBOXANES TX	15	5.51e-01	-0.088900	8.97e-01
REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	30	5.53e-01	0.062500	8.99e-01
REACTOME SIGNALING BY NOTCH1	69	5.55e-01	-0.041100	8.99e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF ADDITIONAL CELL CYCLE GENES WHOSE EXACT ROLE IN THE P53 PATHWAY REMAIN UNCERTAIN	21	5.55e-01	0.074400	8.99e-01
REACTOME SUMO IS PROTEOLYTICALLY PROCESSED	6	5.55e-01	0.139000	8.99e-01
REACTOME ELECTRIC TRANSMISSION ACROSS GAP JUNCTIONS	5	5.56e-01	0.152000	8.99e-01
REACTOME TRANSCRIPTIONAL REGULATION BY THE AP 2 TFAP2 FAMILY OF TRANSCRIPTION FACTORS	36	5.56e-01	-0.056700	8.99e-01
REACTOME REGULATION OF HSF1 MEDIATED HEAT SHOCK RESPONSE	81	5.57e-01	0.037700	8.99e-01
REACTOME BETA OXIDATION OF BUTANOYL COA TO ACETYL COA	5	5.57e-01	-0.152000	8.99e-01
REACTOME SLC TRANSPORTER DISORDERS	94	5.57e-01	-0.035000	8.99e-01
REACTOME ANCHORING OF THE BASAL BODY TO THE PLASMA MEMBRANE	93	5.58e-01	-0.035200	8.99e-01
REACTOME MITOTIC G2 G2 M PHASES	194	5.59e-01	-0.024300	8.99e-01
REACTOME RHOBTB GTPASE CYCLE	34	5.59e-01	-0.057900	8.99e-01
REACTOME FCERI MEDIATED MAPK ACTIVATION	32	5.59e-01	-0.059600	8.99e-01
REACTOME FORMATION OF XYLULOSE 5 PHOSPHATE	5	5.60e-01	0.150000	8.99e-01
REACTOME ADRENALINE NORADRENALINE INHIBITS INSULIN SECRETION	28	5.62e-01	-0.063300	8.99e-01
REACTOME MITOTIC PROPHASE	134	5.63e-01	-0.029000	8.99e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONES	11	5.63e-01	-0.101000	8.99e-01
REACTOME SYNTHESIS OF 12 EICOSATETRAENOIC ACID DERIVATIVES	7	5.63e-01	-0.126000	8.99e-01
REACTOME ORGANIC ANION TRANSPORTERS	10	5.63e-01	0.106000	8.99e-01
REACTOME TRANSLESION SYNTHESIS BY Y FAMILY DNA POLYMERASES BYPASSES LESIONS ON DNA TEMPLATE	39	5.65e-01	-0.053300	9.01e-01
REACTOME SYNTHESIS OF DIPHTHAMIDE EEF2	8	5.66e-01	-0.117000	9.02e-01
REACTOME SEPARATION OF SISTER CHROMATIDS	184	5.66e-01	0.024500	9.02e-01
REACTOME TRANSPORT OF THE SLBP DEPENDANT MATURE MRNA	36	5.67e-01	-0.055100	9.02e-01
REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	21	5.69e-01	-0.071800	9.02e-01
REACTOME SARS COV INFECTIONS	392	5.69e-01	-0.016800	9.02e-01
REACTOME REPRODUCTION	136	5.69e-01	0.028300	9.02e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH PI3K	7	5.69e-01	0.124000	9.02e-01
REACTOME ACETYLCHOLINE INHIBITS CONTRACTION OF OUTER HAIR CELLS	5	5.69e-01	-0.147000	9.02e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 1 PROMOTER	28	5.73e-01	-0.061600	9.05e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF DNA REPAIR GENES	61	5.73e-01	-0.041700	9.05e-01
REACTOME RRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	58	5.73e-01	-0.042700	9.05e-01
REACTOME MASTL FACILITATES MITOTIC PROGRESSION	10	5.74e-01	0.103000	9.05e-01
REACTOME PURINERGIC SIGNALING IN LEISHMANIASIS INFECTION	26	5.74e-01	-0.063700	9.05e-01
REACTOME PHOSPHORYLATION OF EMI1	6	5.77e-01	0.132000	9.06e-01
REACTOME SENSORY PROCESSING OF SOUND BY OUTER HAIR CELLS OF THE COCHLEA	52	5.77e-01	0.044700	9.06e-01
REACTOME TRANSLATION OF SARS COV 2 STRUCTURAL PROTEINS	55	5.77e-01	-0.043500	9.06e-01
REACTOME AMINE LIGAND BINDING RECEPTORS	40	5.77e-01	-0.050900	9.06e-01
REACTOME EPITHELIAL MESENCHYMAL TRANSITION EMT DURING GASTRULATION	7	5.78e-01	0.122000	9.06e-01
REACTOME METABOLISM OF FAT SOLUBLE VITAMINS	46	5.79e-01	0.047300	9.06e-01
REACTOME SIGNALING BY LRP5 MUTANTS	6	5.80e-01	-0.131000	9.06e-01
REACTOME TRANSCRIPTION OF THE HIV GENOME	66	5.80e-01	-0.039300	9.06e-01
REACTOME ACTIVATION OF ANTERIOR HOX GENES IN HINDBRAIN DEVELOPMENT DURING EARLY EMBRYOGENESIS	113	5.81e-01	-0.030000	9.06e-01
REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	11	5.81e-01	0.096000	9.06e-01
REACTOME INTEGRATION OF PROVIRUS	9	5.82e-01	0.106000	9.06e-01
REACTOME CYTOSOLIC SENSORS OF PATHOGEN ASSOCIATED DNA	63	5.82e-01	-0.040100	9.06e-01
REACTOME GLYCOLYSIS	70	5.82e-01	-0.038000	9.06e-01
REACTOME FCGR ACTIVATION	11	5.83e-01	-0.095700	9.06e-01
REACTOME ETHANOL OXIDATION	12	5.83e-01	0.091500	9.06e-01
REACTOME PHOSPHATE BOND HYDROLYSIS BY NTPDASE PROTEINS	8	5.84e-01	0.112000	9.06e-01
REACTOME KSRP KHSRP BINDS AND DESTABILIZES MRNA	17	5.84e-01	0.076600	9.06e-01
REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	26	5.85e-01	0.061800	9.06e-01
REACTOME HOMOLOGOUS DNA PAIRING AND STRAND EXCHANGE	43	5.86e-01	-0.048000	9.06e-01
REACTOME G ALPHA S SIGNALLING EVENTS	155	5.86e-01	-0.025300	9.06e-01
REACTOME SUMO IS TRANSFERRED FROM E1 TO E2 UBE2I UBC9	7	5.86e-01	0.119000	9.06e-01
REACTOME ANDROGEN BIOSYNTHESIS	11	5.87e-01	-0.094500	9.06e-01
REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	15	5.89e-01	0.080600	9.07e-01
REACTOME ACTIVATION OF AMPK DOWNSTREAM OF NMDARS	28	5.89e-01	-0.059000	9.07e-01
REACTOME TRANSPORT OF ORGANIC ANIONS	10	5.90e-01	0.098400	9.07e-01
REACTOME FORMATION OF INCISION COMPLEX IN GG NER	40	5.91e-01	0.049100	9.07e-01
REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	20	5.91e-01	0.069300	9.07e-01
REACTOME O LINKED GLYCOSYLATION	109	5.91e-01	0.029800	9.07e-01
REACTOME RUNX3 REGULATES IMMUNE RESPONSE AND CELL MIGRATION	6	5.92e-01	0.126000	9.07e-01
REACTOME TCF DEPENDENT SIGNALING IN RESPONSE TO WNT	222	5.94e-01	0.020800	9.08e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY REMODELING AND CLEARANCE	74	5.94e-01	-0.035900	9.08e-01
REACTOME SIGNALING BY PTK6	54	5.94e-01	-0.041900	9.08e-01
REACTOME RESPONSE OF EIF2AK1 HRI TO HEME DEFICIENCY	14	5.96e-01	0.081800	9.10e-01
REACTOME LDL CLEARANCE	19	5.96e-01	-0.070200	9.10e-01
REACTOME N GLYCAN TRIMMING AND ELONGATION IN THE CIS GOLGI	5	5.98e-01	0.136000	9.11e-01
REACTOME HIV TRANSCRIPTION INITIATION	43	5.98e-01	-0.046500	9.11e-01
REACTOME GLUCONEOGENESIS	33	6.01e-01	-0.052500	9.15e-01
REACTOME C TYPE LECTIN RECEPTORS CLRS	136	6.02e-01	-0.025900	9.15e-01
REACTOME TNFR1 INDUCED NFKAPPAB SIGNALING PATHWAY	30	6.03e-01	0.054800	9.16e-01
REACTOME DEFENSINS	33	6.04e-01	0.052200	9.16e-01
REACTOME SNRNP ASSEMBLY	53	6.04e-01	0.041100	9.16e-01
REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	24	6.05e-01	-0.061100	9.16e-01
REACTOME IRAK4 DEFICIENCY TLR2 4	17	6.06e-01	-0.072300	9.17e-01
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	101	6.07e-01	-0.029700	9.17e-01
REACTOME INTERLEUKIN 27 SIGNALING	11	6.07e-01	-0.089600	9.17e-01
REACTOME FORMATION OF THE BETA CATENIN TCF TRANSACTIVATING COMPLEX	85	6.08e-01	0.032200	9.18e-01
REACTOME SIGNALING BY FGFR4	40	6.09e-01	0.046700	9.18e-01
REACTOME SIGNALING BY FGFR2 IN DISEASE	42	6.12e-01	-0.045200	9.18e-01
REACTOME SIGNALING BY NOTCH2	32	6.12e-01	0.051700	9.18e-01
REACTOME CONJUGATION OF BENZOATE WITH GLYCINE	6	6.12e-01	0.119000	9.18e-01
REACTOME RAS SIGNALING DOWNSTREAM OF NF1 LOSS OF FUNCTION VARIANTS	7	6.13e-01	-0.110000	9.18e-01
REACTOME TRANSCRIPTIONAL REGULATION BY NPAS4	33	6.14e-01	-0.050800	9.18e-01
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	16	6.14e-01	-0.072900	9.18e-01
REACTOME HEME BIOSYNTHESIS	13	6.14e-01	0.080800	9.18e-01
REACTOME O LINKED GLYCOSYLATION OF MUCINS	61	6.14e-01	0.037300	9.18e-01
REACTOME ACYL CHAIN REMODELLING OF PS	22	6.14e-01	-0.062000	9.18e-01
REACTOME SUMOYLATION OF RNA BINDING PROTEINS	47	6.15e-01	-0.042300	9.18e-01
REACTOME PROGRAMMED CELL DEATH	204	6.16e-01	-0.020400	9.18e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL DEATH GENES	15	6.16e-01	-0.074800	9.18e-01
REACTOME INTERLEUKIN 20 FAMILY SIGNALING	25	6.16e-01	-0.057900	9.18e-01
REACTOME INSERTION OF TAIL ANCHORED PROTEINS INTO THE ENDOPLASMIC RETICULUM MEMBRANE	20	6.17e-01	-0.064600	9.18e-01
REACTOME MRNA SPLICING MINOR PATHWAY	49	6.18e-01	-0.041200	9.18e-01
REACTOME SIGNALING BY FGFR1	49	6.19e-01	-0.041100	9.18e-01
REACTOME PROCESSING OF DNA DOUBLE STRAND BREAK ENDS	93	6.19e-01	0.029900	9.18e-01
REACTOME INTERACTIONS OF REV WITH HOST CELLULAR PROTEINS	37	6.19e-01	-0.047200	9.18e-01
REACTOME PI 3K CASCADE FGFR1	21	6.20e-01	0.062600	9.18e-01
REACTOME SPRY REGULATION OF FGF SIGNALING	16	6.23e-01	-0.071000	9.18e-01
REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	20	6.23e-01	-0.063500	9.18e-01
REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	38	6.23e-01	0.046000	9.18e-01
REACTOME INTERLEUKIN 23 SIGNALING	9	6.24e-01	-0.094500	9.18e-01
REACTOME ROLE OF ABL IN ROBO SLIT SIGNALING	8	6.25e-01	-0.099800	9.18e-01
REACTOME REGULATION OF BETA CELL DEVELOPMENT	41	6.27e-01	-0.043900	9.18e-01
REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	27	6.28e-01	-0.053900	9.18e-01
REACTOME PIWI INTERACTING RNA PIRNA BIOGENESIS	29	6.28e-01	-0.052000	9.18e-01
REACTOME SUMOYLATION OF INTRACELLULAR RECEPTORS	29	6.28e-01	-0.051900	9.18e-01
REACTOME COLLAGEN DEGRADATION	61	6.29e-01	0.035800	9.18e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH PHOSPHORYLATION	89	6.29e-01	0.029600	9.18e-01
REACTOME LIPOPHAGY	9	6.30e-01	-0.092900	9.18e-01
REACTOME TRYPTOPHAN CATABOLISM	14	6.30e-01	-0.074500	9.18e-01
REACTOME RNA POLYMERASE II TRANSCRIPTION TERMINATION	62	6.30e-01	-0.035400	9.18e-01
REACTOME COLLAGEN BIOSYNTHESIS AND MODIFYING ENZYMES	65	6.31e-01	0.034500	9.18e-01
REACTOME RHO GTPASES ACTIVATE RHOTEKIN AND RHOPHILINS	9	6.31e-01	-0.092500	9.18e-01
REACTOME MOLECULES ASSOCIATED WITH ELASTIC FIBRES	37	6.31e-01	-0.045600	9.18e-01
REACTOME FOXO MEDIATED TRANSCRIPTION OF CELL CYCLE GENES	16	6.31e-01	0.069300	9.18e-01
REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	26	6.31e-01	0.054400	9.18e-01
REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	19	6.33e-01	0.063300	9.18e-01
REACTOME EXTRACELLULAR MATRIX ORGANIZATION	291	6.34e-01	-0.016200	9.18e-01
REACTOME BETA OXIDATION OF DECANOYL COA TO OCTANOYL COA COA	6	6.34e-01	-0.112000	9.18e-01
REACTOME SIGNALING BY CSF1 M CSF IN MYELOID CELLS	30	6.36e-01	0.049900	9.18e-01
REACTOME SIGNALING BY HEDGEHOG	148	6.36e-01	0.022500	9.18e-01
REACTOME ION CHANNEL TRANSPORT	172	6.38e-01	-0.020800	9.18e-01
REACTOME EICOSANOID LIGAND BINDING RECEPTORS	14	6.38e-01	-0.072600	9.18e-01
REACTOME SPERM MOTILITY AND TAXES	9	6.38e-01	0.090500	9.18e-01
REACTOME POSTMITOTIC NUCLEAR PORE COMPLEX NPC REFORMATION	27	6.38e-01	-0.052200	9.18e-01
REACTOME 2 LTR CIRCLE FORMATION	7	6.39e-01	0.102000	9.18e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN BCR SIGNALING	6	6.40e-01	0.110000	9.18e-01
REACTOME UPTAKE AND FUNCTION OF DIPHTHERIA TOXIN	6	6.41e-01	-0.110000	9.18e-01
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	361	6.41e-01	-0.014300	9.18e-01
REACTOME PP2A MEDIATED DEPHOSPHORYLATION OF KEY METABOLIC FACTORS	6	6.42e-01	-0.110000	9.18e-01
REACTOME TRISTETRAPROLIN TTP ZFP36 BINDS AND DESTABILIZES MRNA	17	6.42e-01	-0.065000	9.18e-01
REACTOME DISEASES ASSOCIATED WITH N GLYCOSYLATION OF PROTEINS	19	6.43e-01	-0.061400	9.18e-01
REACTOME ASSEMBLY AND CELL SURFACE PRESENTATION OF NMDA RECEPTORS	41	6.43e-01	-0.041800	9.18e-01
REACTOME ASSEMBLY OF THE HIV VIRION	16	6.44e-01	0.066700	9.18e-01
REACTOME GLUCAGON TYPE LIGAND RECEPTORS	32	6.44e-01	-0.047100	9.18e-01
REACTOME GP1B IX V ACTIVATION SIGNALLING	11	6.45e-01	0.080300	9.18e-01
REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX WITHIN TLR4 COMPLEX	15	6.45e-01	-0.068800	9.18e-01
REACTOME GENE SILENCING BY RNA	133	6.45e-01	-0.023100	9.18e-01
REACTOME PROSTANOID LIGAND RECEPTORS	9	6.46e-01	0.088500	9.18e-01
REACTOME EARLY SARS COV 2 INFECTION EVENTS	34	6.46e-01	-0.045600	9.18e-01
REACTOME SODIUM COUPLED PHOSPHATE COTRANSPORTERS	5	6.46e-01	-0.119000	9.18e-01
REACTOME INTERLEUKIN 12 FAMILY SIGNALING	53	6.47e-01	0.036400	9.18e-01
REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	39	6.48e-01	-0.042200	9.18e-01
REACTOME DARPP 32 EVENTS	24	6.49e-01	-0.053700	9.18e-01
REACTOME OTHER INTERLEUKIN SIGNALING	24	6.49e-01	-0.053700	9.18e-01
REACTOME RELEASE OF HH NP FROM THE SECRETING CELL	8	6.49e-01	0.092900	9.18e-01
REACTOME DNA STRAND ELONGATION	31	6.50e-01	-0.047100	9.18e-01
REACTOME SIGNALING BY NOTCH1 PEST DOMAIN MUTANTS IN CANCER	54	6.50e-01	-0.035700	9.18e-01
REACTOME REGULATION OF TP53 ACTIVITY THROUGH METHYLATION	19	6.51e-01	0.060000	9.18e-01
REACTOME MATURATION OF SARS COV 2 NUCLEOPROTEIN	15	6.51e-01	-0.067400	9.18e-01
REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	37	6.52e-01	-0.042800	9.18e-01
REACTOME CALNEXIN CALRETICULIN CYCLE	26	6.52e-01	0.051100	9.18e-01
REACTOME TRANSCRIPTIONAL REGULATION OF GRANULOPOIESIS	83	6.52e-01	-0.028600	9.18e-01
REACTOME THE ACTIVATION OF ARYLSULFATASES	8	6.53e-01	-0.091900	9.18e-01
REACTOME RUNX1 REGULATES GENES INVOLVED IN MEGAKARYOCYTE DIFFERENTIATION AND PLATELET FUNCTION	90	6.53e-01	-0.027500	9.18e-01
REACTOME FRS MEDIATED FGFR1 SIGNALING	23	6.53e-01	-0.054100	9.18e-01
REACTOME COOPERATION OF PREFOLDIN AND TRIC CCT IN ACTIN AND TUBULIN FOLDING	32	6.54e-01	0.045800	9.18e-01
REACTOME METABOLISM OF RNA	675	6.54e-01	0.010100	9.18e-01
REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	129	6.55e-01	0.022800	9.18e-01
REACTOME RETROGRADE TRANSPORT AT THE TRANS GOLGI NETWORK	47	6.55e-01	-0.037700	9.18e-01
REACTOME SIGNALING BY TGFB FAMILY MEMBERS	119	6.56e-01	-0.023600	9.19e-01
REACTOME MET ACTIVATES PTPN11	5	6.59e-01	0.114000	9.23e-01
REACTOME TACHYKININ RECEPTORS BIND TACHYKININS	5	6.64e-01	0.112000	9.28e-01
REACTOME BICARBONATE TRANSPORTERS	10	6.65e-01	-0.079100	9.28e-01
REACTOME SIGNALING BY CTNNB1 PHOSPHO SITE MUTANTS	14	6.65e-01	-0.066800	9.28e-01
REACTOME ATTACHMENT AND ENTRY	16	6.66e-01	0.062300	9.28e-01
REACTOME PTK6 PROMOTES HIF1A STABILIZATION	6	6.66e-01	0.102000	9.28e-01
REACTOME GLUCAGON LIKE PEPTIDE 1 GLP1 REGULATES INSULIN SECRETION	42	6.67e-01	-0.038400	9.28e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX	91	6.68e-01	-0.026000	9.28e-01
REACTOME SYNTHESIS OF UDP N ACETYL GLUCOSAMINE	7	6.68e-01	-0.093500	9.28e-01
REACTOME DISASSEMBLY OF THE DESTRUCTION COMPLEX AND RECRUITMENT OF AXIN TO THE MEMBRANE	30	6.69e-01	-0.045200	9.28e-01
REACTOME SIGNALING BY ERBB2 ECD MUTANTS	16	6.69e-01	-0.061800	9.28e-01
REACTOME LATE SARS COV 2 INFECTION EVENTS	67	6.69e-01	-0.030200	9.28e-01
REACTOME DISSOLUTION OF FIBRIN CLOT	13	6.72e-01	0.067800	9.31e-01
REACTOME TELOMERE MAINTENANCE	106	6.72e-01	0.023800	9.31e-01
REACTOME BETA OXIDATION OF PRISTANOYL COA	9	6.73e-01	-0.081100	9.31e-01
REACTOME SUMOYLATION OF IMMUNE RESPONSE PROTEINS	10	6.73e-01	-0.077000	9.31e-01
REACTOME MOLYBDENUM COFACTOR BIOSYNTHESIS	6	6.75e-01	-0.098900	9.32e-01
REACTOME ABERRANT REGULATION OF MITOTIC EXIT IN CANCER DUE TO RB1 DEFECTS	20	6.76e-01	0.053900	9.33e-01
REACTOME NOSTRIN MEDIATED ENOS TRAFFICKING	5	6.77e-01	-0.108000	9.33e-01
REACTOME SUMOYLATION OF DNA DAMAGE RESPONSE AND REPAIR PROTEINS	74	6.78e-01	-0.027900	9.34e-01
REACTOME CYCLIN D ASSOCIATED EVENTS IN G1	46	6.78e-01	-0.035300	9.34e-01
REACTOME SIGNAL REGULATORY PROTEIN FAMILY INTERACTIONS	16	6.79e-01	-0.059700	9.34e-01
REACTOME ACYL CHAIN REMODELLING OF PE	29	6.82e-01	-0.043900	9.37e-01
REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX IN CANCER	8	6.83e-01	-0.083300	9.37e-01
REACTOME GABA B RECEPTOR ACTIVATION	43	6.83e-01	-0.035900	9.37e-01
REACTOME MITOTIC METAPHASE AND ANAPHASE	228	6.84e-01	-0.015700	9.37e-01
REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	16	6.84e-01	0.058700	9.37e-01
REACTOME SUMOYLATION	179	6.85e-01	-0.017600	9.37e-01
REACTOME SIGNALLING TO P38 VIA RIT AND RIN	5	6.85e-01	0.105000	9.37e-01
REACTOME SULFUR AMINO ACID METABOLISM	27	6.87e-01	-0.044800	9.38e-01
REACTOME MEIOTIC RECOMBINATION	80	6.89e-01	0.025900	9.40e-01
REACTOME INTERLEUKIN 3 INTERLEUKIN 5 AND GM CSF SIGNALING	45	6.90e-01	-0.034400	9.40e-01
REACTOME IL 6 TYPE CYTOKINE RECEPTOR LIGAND INTERACTIONS	17	6.90e-01	0.055900	9.40e-01
REACTOME NPAS4 REGULATES EXPRESSION OF TARGET GENES	21	6.92e-01	-0.049900	9.42e-01
REACTOME SYNAPTIC ADHESION LIKE MOLECULES	19	6.94e-01	-0.052200	9.42e-01
REACTOME DNA METHYLATION	58	6.94e-01	0.029900	9.42e-01
REACTOME EPH EPHRIN MEDIATED REPULSION OF CELLS	50	6.95e-01	-0.032100	9.42e-01
REACTOME SIGNALING BY MET	78	6.95e-01	-0.025700	9.42e-01
REACTOME RAP1 SIGNALLING	16	6.97e-01	0.056300	9.42e-01
REACTOME HYALURONAN METABOLISM	17	6.97e-01	0.054600	9.42e-01
REACTOME HS GAG DEGRADATION	19	6.97e-01	0.051600	9.42e-01
REACTOME EXTENSION OF TELOMERES	49	6.97e-01	-0.032100	9.42e-01
REACTOME PHYSIOLOGICAL FACTORS	14	6.97e-01	0.060000	9.42e-01
REACTOME CONSTITUTIVE SIGNALING BY EGFRVIII	15	6.98e-01	-0.058000	9.42e-01
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE	53	6.99e-01	-0.030700	9.43e-01
REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	36	6.99e-01	0.037200	9.43e-01
REACTOME RHO GTPASES ACTIVATE PKNS	86	7.00e-01	-0.024100	9.43e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH RAS	9	7.02e-01	-0.073600	9.44e-01
REACTOME RUNX2 REGULATES BONE DEVELOPMENT	29	7.03e-01	-0.040900	9.44e-01
REACTOME FC EPSILON RECEPTOR FCERI SIGNALING	127	7.03e-01	0.019600	9.44e-01
REACTOME SUMOYLATION OF DNA REPLICATION PROTEINS	46	7.04e-01	-0.032400	9.44e-01
REACTOME EARLY PHASE OF HIV LIFE CYCLE	14	7.04e-01	0.058700	9.44e-01
REACTOME OXIDATIVE STRESS INDUCED SENESCENCE	118	7.04e-01	-0.020200	9.44e-01
REACTOME PROTEIN LOCALIZATION	153	7.05e-01	-0.017700	9.44e-01
REACTOME REGULATION OF PLK1 ACTIVITY AT G2 M TRANSITION	84	7.06e-01	-0.023800	9.44e-01
REACTOME TRANSPORT AND SYNTHESIS OF PAPS	6	7.07e-01	-0.088500	9.44e-01
REACTOME SUMOYLATION OF SUMOYLATION PROTEINS	35	7.07e-01	-0.036700	9.44e-01
REACTOME INTERLEUKIN 1 FAMILY SIGNALING	146	7.07e-01	0.018000	9.44e-01
REACTOME POLO LIKE KINASE MEDIATED EVENTS	16	7.08e-01	-0.054100	9.44e-01
REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	13	7.09e-01	-0.059700	9.45e-01
REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	17	7.11e-01	-0.052000	9.46e-01
REACTOME G0 AND EARLY G1	27	7.13e-01	-0.041000	9.47e-01
REACTOME METAL SEQUESTRATION BY ANTIMICROBIAL PROTEINS	6	7.13e-01	-0.086900	9.47e-01
REACTOME INTEGRIN SIGNALING	27	7.14e-01	0.040800	9.48e-01
REACTOME AKT PHOSPHORYLATES TARGETS IN THE NUCLEUS	9	7.15e-01	-0.070400	9.49e-01
REACTOME SARS COV 2 TARGETS PDZ PROTEINS IN CELL CELL JUNCTION	5	7.16e-01	0.094000	9.49e-01
REACTOME RHOBTB2 GTPASE CYCLE	22	7.18e-01	-0.044500	9.50e-01
REACTOME ACTIVATION OF PPARGC1A PGC 1ALPHA BY PHOSPHORYLATION	10	7.18e-01	0.065900	9.50e-01
REACTOME SYNTHESIS OF PI	5	7.18e-01	0.093100	9.50e-01
REACTOME LDL REMODELING	6	7.19e-01	-0.084800	9.51e-01
REACTOME VASOPRESSIN LIKE RECEPTORS	5	7.20e-01	-0.092600	9.51e-01
REACTOME REGULATED NECROSIS	57	7.21e-01	-0.027300	9.52e-01
REACTOME MET ACTIVATES PI3K AKT SIGNALING	6	7.22e-01	0.083900	9.52e-01
REACTOME SIGNALING BY NOTCH	234	7.25e-01	-0.013400	9.52e-01
REACTOME NEUROTRANSMITTER CLEARANCE	9	7.26e-01	-0.067600	9.52e-01
REACTOME MISMATCH REPAIR	15	7.26e-01	0.052200	9.52e-01
REACTOME LAMININ INTERACTIONS	28	7.27e-01	0.038200	9.52e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION LINKED TO TRIGLYCERIDE LIPOLYSIS IN ADIPOSE	5	7.28e-01	-0.090000	9.52e-01
REACTOME SIGNAL ATTENUATION	10	7.28e-01	-0.063600	9.52e-01
REACTOME NICOTINATE METABOLISM	31	7.28e-01	0.036100	9.52e-01
REACTOME UNBLOCKING OF NMDA RECEPTORS GLUTAMATE BINDING AND ACTIVATION	19	7.28e-01	-0.046000	9.52e-01
REACTOME TP53 REGULATES TRANSCRIPTION OF CELL CYCLE GENES	49	7.28e-01	-0.028700	9.52e-01
REACTOME REGULATION OF COMMISSURAL AXON PATHFINDING BY SLIT AND ROBO	10	7.29e-01	0.063400	9.52e-01
REACTOME RECYCLING OF BILE ACIDS AND SALTS	18	7.29e-01	0.047200	9.52e-01
REACTOME PURINE SALVAGE	12	7.29e-01	0.057700	9.52e-01
REACTOME SEMA4D IN SEMAPHORIN SIGNALING	24	7.30e-01	-0.040700	9.52e-01
REACTOME BH3 ONLY PROTEINS ASSOCIATE WITH AND INACTIVATE ANTI APOPTOTIC BCL 2 MEMBERS	9	7.30e-01	-0.066500	9.52e-01
REACTOME DOPAMINE RECEPTORS	5	7.30e-01	-0.089000	9.52e-01
REACTOME POU5F1 OCT4 SOX2 NANOG ACTIVATE GENES RELATED TO PROLIFERATION	11	7.31e-01	0.059900	9.52e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO LIMIT CHOLESTEROL UPTAKE	5	7.32e-01	-0.088400	9.52e-01
REACTOME FRS MEDIATED FGFR3 SIGNALING	19	7.33e-01	0.045200	9.52e-01
REACTOME REGULATION OF TLR BY ENDOGENOUS LIGAND	21	7.33e-01	-0.043000	9.52e-01
REACTOME METALLOPROTEASE DUBS	36	7.35e-01	0.032600	9.53e-01
REACTOME CALCITONIN LIKE LIGAND RECEPTORS	10	7.35e-01	0.061700	9.53e-01
REACTOME COMPLEMENT CASCADE	54	7.36e-01	0.026500	9.53e-01
REACTOME PEROXISOMAL LIPID METABOLISM	28	7.37e-01	-0.036700	9.53e-01
REACTOME REGULATION OF TP53 EXPRESSION AND DEGRADATION	37	7.37e-01	-0.031900	9.53e-01
REACTOME APEX1 INDEPENDENT RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	7	7.38e-01	0.073100	9.53e-01
REACTOME DISEASES OF BASE EXCISION REPAIR	5	7.39e-01	0.086200	9.53e-01
REACTOME OREXIN AND NEUROPEPTIDES FF AND QRFP BIND TO THEIR RESPECTIVE RECEPTORS	8	7.39e-01	0.068100	9.53e-01
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	51	7.39e-01	-0.027000	9.53e-01
REACTOME HORMONE LIGAND BINDING RECEPTORS	12	7.39e-01	0.055500	9.53e-01
REACTOME RUNX1 REGULATES TRANSCRIPTION OF GENES INVOLVED IN DIFFERENTIATION OF KERATINOCYTES	8	7.40e-01	-0.067800	9.53e-01
REACTOME PCNA DEPENDENT LONG PATCH BASE EXCISION REPAIR	21	7.41e-01	-0.041700	9.53e-01
REACTOME INTERLEUKIN 6 FAMILY SIGNALING	24	7.43e-01	0.038600	9.53e-01
REACTOME BUDDING AND MATURATION OF HIV VIRION	28	7.43e-01	-0.035800	9.53e-01
REACTOME DISEASES OF CARBOHYDRATE METABOLISM	31	7.43e-01	0.034000	9.53e-01
REACTOME IRS MEDIATED SIGNALLING	47	7.43e-01	-0.027600	9.53e-01
REACTOME ION HOMEOSTASIS	52	7.44e-01	-0.026200	9.53e-01
REACTOME SIGNALING BY FGFR1 IN DISEASE	38	7.44e-01	-0.030600	9.53e-01
REACTOME FRS MEDIATED FGFR2 SIGNALING	24	7.45e-01	-0.038400	9.53e-01
REACTOME SIGNALING BY MST1	5	7.46e-01	0.083600	9.53e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION	102	7.47e-01	-0.018500	9.53e-01
REACTOME REPRESSION OF WNT TARGET GENES	14	7.48e-01	0.049600	9.53e-01
REACTOME CHYLOMICRON ASSEMBLY	10	7.48e-01	0.058600	9.53e-01
REACTOME UREA CYCLE	9	7.49e-01	0.061500	9.53e-01
REACTOME GENE AND PROTEIN EXPRESSION BY JAK STAT SIGNALING AFTER INTERLEUKIN 12 STIMULATION	35	7.50e-01	0.031100	9.53e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION TERMINATION	23	7.50e-01	0.038300	9.53e-01
REACTOME NEGATIVE REGULATION OF MET ACTIVITY	20	7.51e-01	0.041100	9.53e-01
REACTOME PLASMA LIPOPROTEIN CLEARANCE	37	7.53e-01	0.029900	9.53e-01
REACTOME METABOLISM OF COFACTORS	19	7.54e-01	0.041600	9.53e-01
REACTOME DEADENYLATION OF MRNA	25	7.54e-01	0.036200	9.53e-01
REACTOME G2 M DNA DAMAGE CHECKPOINT	90	7.54e-01	0.019100	9.53e-01
REACTOME SENSING OF DNA DOUBLE STRAND BREAKS	6	7.55e-01	-0.073700	9.53e-01
REACTOME VLDL CLEARANCE	6	7.56e-01	0.073200	9.53e-01
REACTOME FLT3 SIGNALING IN DISEASE	28	7.56e-01	-0.033900	9.53e-01
REACTOME DIGESTION OF DIETARY CARBOHYDRATE	6	7.57e-01	0.073100	9.53e-01
REACTOME SEMA4D MEDIATED INHIBITION OF CELL ATTACHMENT AND MIGRATION	8	7.57e-01	0.063300	9.53e-01
REACTOME CTLA4 INHIBITORY SIGNALING	21	7.57e-01	-0.039000	9.53e-01
REACTOME COOPERATION OF PDCL PHLP1 AND TRIC CCT IN G PROTEIN BETA FOLDING	38	7.57e-01	-0.029000	9.53e-01
REACTOME BIOSYNTHESIS OF SPECIALIZED PRORESOLVING MEDIATORS SPMS	19	7.57e-01	0.041000	9.53e-01
REACTOME REGULATION OF NF KAPPA B SIGNALING	17	7.57e-01	-0.043300	9.53e-01
REACTOME FORMATION OF APOPTOSOME	10	7.58e-01	-0.056300	9.53e-01
REACTOME SYNTHESIS OF IP3 AND IP4 IN THE CYTOSOL	25	7.58e-01	-0.035500	9.53e-01
REACTOME NUCLEAR EVENTS STIMULATED BY ALK SIGNALING IN CANCER	18	7.59e-01	-0.041800	9.53e-01
REACTOME SIGNALING BY PDGF	57	7.59e-01	0.023500	9.53e-01
REACTOME LAGGING STRAND SYNTHESIS	19	7.61e-01	0.040400	9.54e-01
REACTOME EGFR INTERACTS WITH PHOSPHOLIPASE C GAMMA	9	7.61e-01	-0.058500	9.54e-01
REACTOME TRANSCRIPTIONAL REGULATION BY RUNX2	117	7.62e-01	0.016200	9.54e-01
REACTOME NEF AND SIGNAL TRANSDUCTION	8	7.63e-01	0.061500	9.54e-01
REACTOME CRMPS IN SEMA3A SIGNALING	15	7.63e-01	0.044900	9.54e-01
REACTOME LISTERIA MONOCYTOGENES ENTRY INTO HOST CELLS	19	7.63e-01	0.039900	9.54e-01
REACTOME APOPTOTIC FACTOR MEDIATED RESPONSE	19	7.64e-01	0.039800	9.54e-01
REACTOME ERBB2 ACTIVATES PTK6 SIGNALING	13	7.65e-01	0.047900	9.54e-01
REACTOME BETA CATENIN INDEPENDENT WNT SIGNALING	145	7.66e-01	-0.014300	9.55e-01
REACTOME TRNA PROCESSING	105	7.67e-01	-0.016800	9.55e-01
REACTOME RNA POLYMERASE I TRANSCRIPTION TERMINATION	30	7.68e-01	-0.031100	9.55e-01
REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	15	7.69e-01	0.043800	9.55e-01
REACTOME METABOLIC DISORDERS OF BIOLOGICAL OXIDATION ENZYMES	33	7.69e-01	-0.029500	9.55e-01
REACTOME RECEPTOR TYPE TYROSINE PROTEIN PHOSPHATASES	16	7.70e-01	-0.042300	9.55e-01
REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	14	7.70e-01	-0.045100	9.55e-01
REACTOME DEADENYLATION DEPENDENT MRNA DECAY	56	7.72e-01	0.022400	9.55e-01
REACTOME ALPHA OXIDATION OF PHYTANATE	6	7.72e-01	-0.068200	9.55e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCOSE DEPENDENT INSULINOTROPIC POLYPEPTIDE GIP	12	7.73e-01	0.048200	9.55e-01
REACTOME VITAMIN C ASCORBATE METABOLISM	8	7.73e-01	-0.059000	9.55e-01
REACTOME LYSOSPHINGOLIPID AND LPA RECEPTORS	14	7.73e-01	-0.044600	9.55e-01
REACTOME ACTIVATION OF NOXA AND TRANSLOCATION TO MITOCHONDRIA	5	7.74e-01	0.074200	9.56e-01
REACTOME DISEASES OF MISMATCH REPAIR MMR	5	7.74e-01	0.074100	9.56e-01
REACTOME TNFR1 MEDIATED CERAMIDE PRODUCTION	6	7.75e-01	-0.067300	9.57e-01
REACTOME CELLULAR SENESCENCE	189	7.78e-01	-0.011900	9.58e-01
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	13	7.78e-01	-0.045200	9.58e-01
REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	9	7.79e-01	0.053900	9.59e-01
REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	16	7.80e-01	-0.040300	9.59e-01
REACTOME RIPK1 MEDIATED REGULATED NECROSIS	30	7.82e-01	0.029200	9.60e-01
REACTOME METABOLISM OF INGESTED SEMET SEC MESEC INTO H2SE	7	7.82e-01	0.060300	9.60e-01
REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	16	7.83e-01	0.039800	9.60e-01
REACTOME TRANSCRIPTIONAL REGULATION BY SMALL RNAS	100	7.84e-01	0.015900	9.60e-01
REACTOME PROTEIN PROTEIN INTERACTIONS AT SYNAPSES	77	7.84e-01	-0.018100	9.60e-01
REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	16	7.84e-01	0.039500	9.60e-01
REACTOME TERMINATION OF TRANSLESION DNA SYNTHESIS	32	7.85e-01	-0.027900	9.60e-01
REACTOME VITAMIN B1 THIAMIN METABOLISM	5	7.86e-01	-0.070100	9.61e-01
REACTOME RNA POLYMERASE III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	28	7.86e-01	-0.029600	9.61e-01
REACTOME RNA POLYMERASE II TRANSCRIBES SNRNA GENES	77	7.91e-01	-0.017500	9.64e-01
REACTOME NEGATIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	100	7.91e-01	0.015400	9.64e-01
REACTOME CONDENSATION OF PROPHASE CHROMOSOMES	66	7.93e-01	0.018700	9.64e-01
REACTOME INFECTION WITH MYCOBACTERIUM TUBERCULOSIS	25	7.94e-01	-0.030200	9.64e-01
REACTOME NEPHRIN FAMILY INTERACTIONS	22	7.94e-01	-0.032200	9.64e-01
REACTOME DECTIN 2 FAMILY	26	7.95e-01	0.029500	9.64e-01
REACTOME UBIQUINOL BIOSYNTHESIS	8	7.95e-01	-0.053000	9.64e-01
REACTOME NEURONAL SYSTEM	388	7.95e-01	0.007680	9.64e-01
REACTOME ATTACHMENT OF GPI ANCHOR TO UPAR	7	7.96e-01	-0.056400	9.64e-01
REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION	20	7.96e-01	0.033400	9.64e-01
REACTOME PARACETAMOL ADME	26	7.96e-01	0.029200	9.64e-01
REACTOME SIGNALING BY RNF43 MUTANTS	8	7.97e-01	-0.052600	9.64e-01
REACTOME TRANSPORT OF CONNEXONS TO THE PLASMA MEMBRANE	20	7.97e-01	-0.033200	9.64e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR1	31	7.98e-01	-0.026600	9.64e-01
REACTOME OAS ANTIVIRAL RESPONSE	8	7.99e-01	0.052100	9.64e-01
REACTOME SARS COV 2 MODULATES AUTOPHAGY	11	7.99e-01	0.044200	9.64e-01
REACTOME SIGNALING BY PDGFR IN DISEASE	20	8.00e-01	-0.032700	9.64e-01
REACTOME TRNA PROCESSING IN THE NUCLEUS	58	8.01e-01	-0.019200	9.64e-01
REACTOME G1 S SPECIFIC TRANSCRIPTION	28	8.01e-01	-0.027500	9.64e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY P107 RBL1 AND P130 RBL2 IN COMPLEX WITH HDAC1	16	8.02e-01	-0.036200	9.64e-01
REACTOME RECOGNITION OF DNA DAMAGE BY PCNA CONTAINING REPLICATION COMPLEX	29	8.02e-01	0.026900	9.64e-01
REACTOME ARACHIDONIC ACID METABOLISM	57	8.03e-01	-0.019200	9.64e-01
REACTOME DISPLACEMENT OF DNA GLYCOSYLASE BY APEX1	9	8.03e-01	0.048000	9.64e-01
REACTOME DISEASES OF GLYCOSYLATION	137	8.06e-01	-0.012200	9.65e-01
REACTOME NONHOMOLOGOUS END JOINING NHEJ	64	8.06e-01	0.017800	9.65e-01
REACTOME SEMAPHORIN INTERACTIONS	61	8.06e-01	-0.018200	9.65e-01
REACTOME HDMS DEMETHYLATE HISTONES	40	8.07e-01	0.022300	9.65e-01
REACTOME CLEC7A DECTIN 1 SIGNALING	97	8.08e-01	-0.014300	9.65e-01
REACTOME SELECTIVE AUTOPHAGY	79	8.09e-01	-0.015800	9.65e-01
REACTOME APOPTOTIC EXECUTION PHASE	49	8.09e-01	0.020000	9.65e-01
REACTOME NUCLEOTIDE SALVAGE	21	8.10e-01	-0.030400	9.65e-01
REACTOME BASIGIN INTERACTIONS	24	8.10e-01	-0.028300	9.65e-01
REACTOME TNF SIGNALING	54	8.11e-01	-0.018800	9.65e-01
REACTOME MYOGENESIS	29	8.11e-01	0.025700	9.65e-01
REACTOME FGFR2B LIGAND BINDING AND ACTIVATION	10	8.12e-01	0.043400	9.65e-01
REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	35	8.12e-01	-0.023200	9.65e-01
REACTOME MET ACTIVATES RAP1 AND RAC1	11	8.12e-01	0.041400	9.65e-01
REACTOME VITAMINS	6	8.14e-01	0.055500	9.65e-01
REACTOME SURFACTANT METABOLISM	28	8.14e-01	-0.025600	9.65e-01
REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	14	8.15e-01	0.036100	9.65e-01
REACTOME PLASMA LIPOPROTEIN ASSEMBLY	19	8.15e-01	0.031000	9.65e-01
REACTOME SARS COV 1 HOST INTERACTIONS	92	8.15e-01	0.014100	9.65e-01
REACTOME GLUCOCORTICOID BIOSYNTHESIS	10	8.15e-01	-0.042700	9.65e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	111	8.17e-01	0.012700	9.65e-01
REACTOME L1CAM INTERACTIONS	112	8.17e-01	-0.012700	9.65e-01
REACTOME OPSINS	7	8.17e-01	-0.050400	9.65e-01
REACTOME ER QUALITY CONTROL COMPARTMENT ERQC	21	8.18e-01	0.029000	9.65e-01
REACTOME DDX58 IFIH1 MEDIATED INDUCTION OF INTERFERON ALPHA BETA	77	8.19e-01	0.015100	9.65e-01
REACTOMEMATURATION OF SARS COV 1 NUCLEOPROTEIN	11	8.19e-01	0.039800	9.65e-01
REACTOME FOXO MEDIATED TRANSCRIPTION	65	8.21e-01	-0.016200	9.65e-01
REACTOME DISEASES ASSOCIATED WITH O GLYCOSYLATION OF PROTEINS	66	8.22e-01	0.016000	9.65e-01
REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	10	8.22e-01	0.041100	9.65e-01
REACTOME ATF6 ATF6 ALPHA ACTIVATES CHAPERONE GENES	10	8.22e-01	-0.041100	9.65e-01
REACTOME DNA DAMAGE TELOMERE STRESS INDUCED SENESCENCE	76	8.22e-01	0.014900	9.65e-01
REACTOME SEROTONIN RECEPTORS	11	8.23e-01	-0.038900	9.66e-01
REACTOME FCERI MEDIATED CA 2 MOBILIZATION	30	8.24e-01	-0.023500	9.66e-01
REACTOME BUTYRATE RESPONSE FACTOR 1 BRF1 BINDS AND DESTABILIZES MRNA	17	8.24e-01	-0.031100	9.66e-01
REACTOME ALK MUTANTS BIND TKIS	12	8.25e-01	0.036800	9.67e-01
REACTOME ORGANIC CATION TRANSPORT	10	8.26e-01	0.040200	9.67e-01
REACTOME HYALURONAN UPTAKE AND DEGRADATION	12	8.27e-01	-0.036500	9.67e-01
REACTOME PROCESSIVE SYNTHESIS ON THE C STRAND OF THE TELOMERE	19	8.27e-01	-0.028900	9.67e-01
REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	8	8.28e-01	-0.044400	9.67e-01
REACTOME TRANSPORT OF NUCLEOSIDES AND FREE PURINE AND PYRIMIDINE BASES ACROSS THE PLASMA MEMBRANE	10	8.29e-01	0.039500	9.67e-01
REACTOME SIGNALING BY ERBB4	57	8.31e-01	0.016400	9.68e-01
REACTOME SIGNALING BY RETINOIC ACID	41	8.31e-01	-0.019300	9.68e-01
REACTOME VITAMIN D CALCIFEROL METABOLISM	12	8.31e-01	-0.035600	9.68e-01
REACTOME SIGNALING BY FGFR2 IIIA TM	19	8.32e-01	-0.028100	9.68e-01
REACTOME GERM LAYER FORMATION AT GASTRULATION	17	8.33e-01	-0.029600	9.68e-01
REACTOME ACTIVATED NTRK2 SIGNALS THROUGH CDK5	6	8.34e-01	-0.049300	9.68e-01
REACTOME SIGNALING BY FGFR	85	8.35e-01	-0.013000	9.68e-01
REACTOME ACYL CHAIN REMODELLING OF PG	18	8.36e-01	-0.028300	9.68e-01
REACTOME DUAL INCISION IN GG NER	39	8.36e-01	0.019200	9.68e-01
REACTOME NUCLEAR SIGNALING BY ERBB4	32	8.38e-01	-0.020900	9.68e-01
REACTOME TAK1 DEPENDENT IKK AND NF KAPPA B ACTIVATION	41	8.38e-01	0.018400	9.68e-01
REACTOME INTERLEUKIN 9 SIGNALING	7	8.39e-01	0.044500	9.68e-01
REACTOME TRNA AMINOACYLATION	40	8.39e-01	-0.018600	9.68e-01
REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	23	8.39e-01	-0.024500	9.68e-01
REACTOME SMAC XIAP REGULATED APOPTOTIC RESPONSE	7	8.39e-01	0.044300	9.68e-01
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	35	8.40e-01	0.019700	9.68e-01
REACTOME CLEC7A INFLAMMASOME PATHWAY	6	8.42e-01	0.047100	9.68e-01
REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	16	8.42e-01	-0.028700	9.68e-01
REACTOME ORGANIC ANION TRANSPORT	5	8.43e-01	0.051100	9.68e-01
REACTOME RA BIOSYNTHESIS PATHWAY	22	8.43e-01	0.024300	9.68e-01
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	236	8.44e-01	-0.007460	9.68e-01
REACTOME FGFR1 MUTANT RECEPTOR ACTIVATION	31	8.44e-01	0.020400	9.68e-01
REACTOME INTERLEUKIN 2 SIGNALING	11	8.44e-01	0.034300	9.68e-01
REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	35	8.45e-01	-0.019000	9.68e-01
REACTOME FGFR2 ALTERNATIVE SPLICING	27	8.46e-01	-0.021600	9.68e-01
REACTOME SIGNALING BY FGFR2	72	8.46e-01	-0.013200	9.68e-01
REACTOME RND3 GTPASE CYCLE	41	8.49e-01	0.017200	9.68e-01
REACTOME NEGATIVE REGULATION OF FGFR2 SIGNALING	33	8.49e-01	0.019100	9.68e-01
REACTOME TRNA MODIFICATION IN THE NUCLEUS AND CYTOSOL	41	8.49e-01	-0.017200	9.68e-01
REACTOME REGULATION OF NPAS4 GENE EXPRESSION	13	8.49e-01	-0.030400	9.68e-01
REACTOME EXPORT OF VIRAL RIBONUCLEOPROTEINS FROM NUCLEUS	33	8.50e-01	0.019000	9.68e-01
REACTOME CELL CELL COMMUNICATION	126	8.50e-01	0.009730	9.68e-01
REACTOME TRANSCRIPTIONAL REGULATION BY VENTX	41	8.51e-01	-0.017000	9.68e-01
REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	53	8.51e-01	0.014900	9.68e-01
REACTOME UPTAKE AND ACTIONS OF BACTERIAL TOXINS	28	8.51e-01	0.020500	9.68e-01
REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	20	8.52e-01	-0.024200	9.68e-01
REACTOME FORMATION OF AXIAL MESODERM	14	8.52e-01	0.028900	9.68e-01
REACTOME PI3K EVENTS IN ERBB4 SIGNALING	10	8.53e-01	0.033800	9.68e-01
REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	29	8.53e-01	-0.019800	9.68e-01
REACTOME ZBP1 DAI MEDIATED INDUCTION OF TYPE I IFNS	20	8.54e-01	0.023800	9.68e-01
REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	14	8.54e-01	0.028400	9.68e-01
REACTOME INDUCTION OF CELL CELL FUSION	12	8.54e-01	0.030700	9.68e-01
REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	22	8.56e-01	0.022300	9.68e-01
REACTOME SYNTHESIS OF WYBUTOSINE AT G37 OF TRNA PHE	6	8.57e-01	0.042500	9.68e-01
REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	14	8.57e-01	0.027800	9.68e-01
REACTOME NUCLEOTIDE CATABOLISM	35	8.58e-01	-0.017400	9.68e-01
REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	15	8.60e-01	-0.026200	9.68e-01
REACTOME NR1H2 AND NR1H3 MEDIATED SIGNALING	46	8.61e-01	-0.014900	9.68e-01
REACTOME STAT5 ACTIVATION DOWNSTREAM OF FLT3 ITD MUTANTS	10	8.61e-01	0.031900	9.68e-01
REACTOME TRIGLYCERIDE BIOSYNTHESIS	12	8.62e-01	-0.028900	9.68e-01
REACTOME RIBAVIRIN ADME	11	8.62e-01	-0.030200	9.68e-01
REACTOME SIGNALING BY ERBB2 IN CANCER	26	8.63e-01	-0.019500	9.68e-01
REACTOME COLLAGEN FORMATION	88	8.64e-01	0.010600	9.68e-01
REACTOME GLYOXYLATE METABOLISM AND GLYCINE DEGRADATION	30	8.64e-01	0.018000	9.68e-01
REACTOME INTERLEUKIN 21 SIGNALING	9	8.64e-01	0.032900	9.68e-01
REACTOME KILLING MECHANISMS	11	8.65e-01	-0.029700	9.68e-01
REACTOME IKBA VARIANT LEADS TO EDA ID	6	8.65e-01	-0.040100	9.68e-01
REACTOME ERCC6 CSB AND EHMT2 G9A POSITIVELY REGULATE RRNA EXPRESSION	68	8.65e-01	0.011900	9.68e-01
REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV 1 INFECTION	5	8.65e-01	-0.043800	9.68e-01
REACTOME FGFRL1 MODULATION OF FGFR1 SIGNALING	13	8.65e-01	-0.027100	9.68e-01
REACTOME TRANSPORT OF BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	82	8.66e-01	-0.010800	9.68e-01
REACTOME NOTCH4 ACTIVATION AND TRANSMISSION OF SIGNAL TO THE NUCLEUS	11	8.67e-01	0.029300	9.68e-01
REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	8.67e-01	0.025000	9.68e-01
REACTOME GPCR LIGAND BINDING	444	8.67e-01	-0.004630	9.68e-01
REACTOME TRNA MODIFICATION IN THE MITOCHONDRION	8	8.67e-01	0.034100	9.68e-01
REACTOME LONG TERM POTENTIATION	22	8.69e-01	-0.020200	9.68e-01
REACTOME ABERRANT REGULATION OF MITOTIC G1 S TRANSITION IN CANCER DUE TO RB1 DEFECTS	17	8.71e-01	-0.022800	9.68e-01
REACTOME RHOT1 GTPASE CYCLE	5	8.71e-01	0.041900	9.68e-01
REACTOME CHYLOMICRON CLEARANCE	5	8.71e-01	0.041900	9.68e-01
REACTOME MITOTIC SPINDLE CHECKPOINT	109	8.71e-01	-0.008980	9.68e-01
REACTOME TNF RECEPTOR SUPERFAMILY TNFSF MEMBERS MEDIATING NON CANONICAL NF KB PATHWAY	16	8.72e-01	0.023300	9.68e-01
REACTOME DISEASES OF MITOTIC CELL CYCLE	37	8.72e-01	0.015300	9.68e-01
REACTOME RNA POLYMERASE III CHAIN ELONGATION	18	8.74e-01	0.021600	9.70e-01
REACTOME CS DS DEGRADATION	12	8.75e-01	-0.026200	9.70e-01
REACTOME POSITIVE EPIGENETIC REGULATION OF RRNA EXPRESSION	98	8.76e-01	0.009140	9.70e-01
REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR BCR LEADING TO GENERATION OF SECOND MESSENGERS	28	8.78e-01	-0.016800	9.71e-01
REACTOME FREE FATTY ACID RECEPTORS	5	8.78e-01	0.039700	9.71e-01
REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	18	8.79e-01	0.020800	9.71e-01
REACTOME GAP JUNCTION TRAFFICKING AND REGULATION	49	8.79e-01	0.012500	9.71e-01
REACTOME S PHASE	159	8.80e-01	0.006960	9.71e-01
REACTOME NEF MEDIATED CD8 DOWN REGULATION	7	8.80e-01	0.032900	9.71e-01
REACTOME STRIATED MUSCLE CONTRACTION	35	8.81e-01	0.014600	9.71e-01
REACTOME IRF3 MEDIATED ACTIVATION OF TYPE 1 IFN	5	8.81e-01	0.038500	9.71e-01
REACTOME PRESYNAPTIC DEPOLARIZATION AND CALCIUM CHANNEL OPENING	11	8.82e-01	-0.025800	9.72e-01
REACTOME RUNX3 REGULATES BCL2L11 BIM TRANSCRIPTION	5	8.86e-01	-0.037100	9.75e-01
REACTOME RIP MEDIATED NFKB ACTIVATION VIA ZBP1	16	8.87e-01	0.020500	9.76e-01
REACTOME FGFR2 MUTANT RECEPTOR ACTIVATION	32	8.89e-01	-0.014300	9.77e-01
REACTOME NEUREXINS AND NEUROLIGINS	51	8.89e-01	-0.011300	9.77e-01
REACTOME GLYCOGEN METABOLISM	22	8.91e-01	-0.016900	9.78e-01
REACTOME TERMINAL PATHWAY OF COMPLEMENT	8	8.92e-01	-0.027600	9.79e-01
REACTOME PROCESSING OF INTRONLESS PRE MRNAS	19	8.93e-01	0.017800	9.79e-01
REACTOME RUNX2 REGULATES OSTEOBLAST DIFFERENTIATION	22	8.94e-01	-0.016400	9.79e-01
REACTOME MITOPHAGY	28	8.94e-01	0.014500	9.79e-01
REACTOME RETINOID CYCLE DISEASE EVENTS	11	8.97e-01	0.022600	9.79e-01
REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	49	8.97e-01	0.010700	9.79e-01
REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	15	8.97e-01	-0.019300	9.79e-01
REACTOME APOPTOSIS	173	8.98e-01	-0.005660	9.79e-01
REACTOME ROBO RECEPTORS BIND AKAP5	9	8.98e-01	-0.024700	9.79e-01
REACTOME PRC2 METHYLATES HISTONES AND DNA	65	9.03e-01	-0.008780	9.79e-01
REACTOME TFAP2 AP 2 FAMILY REGULATES TRANSCRIPTION OF CELL CYCLE FACTORS	5	9.03e-01	0.031500	9.79e-01
REACTOME SIGNALING BY EGFR IN CANCER	25	9.03e-01	0.014000	9.79e-01
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	9	9.04e-01	-0.023200	9.79e-01
REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	80	9.04e-01	-0.007800	9.79e-01
REACTOME REGULATION OF INNATE IMMUNE RESPONSES TO CYTOSOLIC DNA	15	9.05e-01	0.017800	9.79e-01
REACTOME MEIOSIS	110	9.05e-01	0.006600	9.79e-01
REACTOME DOWNREGULATION OF ERBB2 SIGNALING	29	9.05e-01	0.012800	9.79e-01
REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	25	9.06e-01	0.013700	9.79e-01
REACTOME RELAXIN RECEPTORS	8	9.07e-01	-0.023800	9.79e-01
REACTOME REGULATION OF GENE EXPRESSION IN LATE STAGE BRANCHING MORPHOGENESIS PANCREATIC BUD PRECURSOR CELLS	15	9.07e-01	-0.017400	9.79e-01
REACTOME NUCLEAR IMPORT OF REV PROTEIN	34	9.07e-01	-0.011500	9.79e-01
REACTOME TELOMERE C STRAND LAGGING STRAND SYNTHESIS	33	9.08e-01	0.011600	9.79e-01
REACTOME RESPONSE OF MTB TO PHAGOCYTOSIS	22	9.09e-01	-0.014200	9.79e-01
REACTOME NR1H2 NR1H3 REGULATE GENE EXPRESSION TO CONTROL BILE ACID HOMEOSTASIS	9	9.09e-01	0.022100	9.79e-01
REACTOME SIGNALING BY TYPE 1 INSULIN LIKE GROWTH FACTOR 1 RECEPTOR IGF1R	52	9.09e-01	-0.009170	9.79e-01
REACTOME ZINC TRANSPORTERS	15	9.09e-01	-0.017000	9.79e-01
REACTOME MECP2 REGULATES NEURONAL RECEPTORS AND CHANNELS	17	9.09e-01	0.015900	9.79e-01
REACTOME SHC RELATED EVENTS TRIGGERED BY IGF1R	9	9.10e-01	-0.021900	9.79e-01
REACTOME CREATINE METABOLISM	9	9.10e-01	-0.021800	9.79e-01
REACTOME SODIUM COUPLED SULPHATE DI AND TRI CARBOXYLATE TRANSPORTERS	5	9.11e-01	0.029000	9.80e-01
REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	46	9.11e-01	-0.009530	9.80e-01
REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	38	9.12e-01	0.010400	9.80e-01
REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	30	9.13e-01	0.011500	9.81e-01
REACTOME ACTIVATION OF THE TFAP2 AP 2 FAMILY OF TRANSCRIPTION FACTORS	11	9.15e-01	0.018600	9.82e-01
REACTOME CLASS I PEROXISOMAL MEMBRANE PROTEIN IMPORT	19	9.16e-01	0.013900	9.83e-01
REACTOME CONDENSATION OF PROMETAPHASE CHROMOSOMES	11	9.18e-01	0.017900	9.84e-01
REACTOME RESPIRATORY ELECTRON TRANSPORT	90	9.18e-01	-0.006250	9.84e-01
REACTOME METHYLATION	14	9.20e-01	0.015600	9.84e-01
REACTOME SARS COV 2 INFECTION	281	9.20e-01	0.003460	9.84e-01
REACTOME REACTIONS SPECIFIC TO THE COMPLEX N GLYCAN SYNTHESIS PATHWAY	10	9.21e-01	0.018100	9.84e-01
REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	15	9.22e-01	-0.014700	9.85e-01
REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	32	9.23e-01	-0.009900	9.85e-01
REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	11	9.24e-01	0.016600	9.85e-01
REACTOME VLDL ASSEMBLY	5	9.25e-01	0.024500	9.85e-01
REACTOME NEGATIVE REGULATION OF FGFR1 SIGNALING	32	9.25e-01	0.009640	9.85e-01
REACTOME THE ROLE OF NEF IN HIV 1 REPLICATION AND DISEASE PATHOGENESIS	27	9.27e-01	-0.010200	9.85e-01
REACTOME ANTIMICROBIAL PEPTIDES	76	9.27e-01	0.006050	9.85e-01
REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	93	9.28e-01	0.005420	9.85e-01
REACTOME CARBOXYTERMINAL POST TRANSLATIONAL MODIFICATIONS OF TUBULIN	45	9.28e-01	-0.007730	9.85e-01
REACTOME ERBB2 REGULATES CELL MOTILITY	15	9.29e-01	0.013300	9.85e-01
REACTOME WAX AND PLASMALOGEN BIOSYNTHESIS	5	9.29e-01	-0.023000	9.85e-01
REACTOME NUCLEAR ENVELOPE BREAKDOWN	52	9.29e-01	-0.007130	9.85e-01
REACTOME REGULATION OF GENE EXPRESSION IN EARLY PANCREATIC PRECURSOR CELLS	8	9.30e-01	-0.018000	9.85e-01
REACTOME NONCANONICAL ACTIVATION OF NOTCH3	8	9.30e-01	-0.017900	9.85e-01
REACTOME CLASS A 1 RHODOPSIN LIKE RECEPTORS	312	9.31e-01	-0.002850	9.85e-01
REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	22	9.32e-01	-0.010600	9.85e-01
REACTOME PHASE 4 RESTING MEMBRANE POTENTIAL	19	9.32e-01	-0.011300	9.85e-01
REACTOME INTERLEUKIN 10 SIGNALING	43	9.33e-01	-0.007450	9.85e-01
REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLUCAGON LIKE PEPTIDE 1 GLP 1	20	9.34e-01	0.010600	9.85e-01
REACTOME RHOH GTPASE CYCLE	37	9.35e-01	0.007730	9.85e-01
REACTOME HDR THROUGH SINGLE STRAND ANNEALING SSA	37	9.36e-01	-0.007680	9.85e-01
REACTOME PURINE CATABOLISM	17	9.37e-01	-0.011100	9.85e-01
REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	7	9.37e-01	0.017100	9.85e-01
REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	23	9.38e-01	0.009390	9.85e-01
REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	15	9.38e-01	0.011600	9.85e-01
REACTOME G PROTEIN ACTIVATION	24	9.38e-01	-0.009170	9.85e-01
REACTOME SIGNALING BY FGFR3	39	9.40e-01	-0.006940	9.85e-01
REACTOME ADHERENS JUNCTIONS INTERACTIONS	33	9.40e-01	0.007540	9.85e-01
REACTOME HS GAG BIOSYNTHESIS	28	9.41e-01	-0.008130	9.85e-01
REACTOME INTERLEUKIN 2 FAMILY SIGNALING	40	9.41e-01	0.006790	9.85e-01
REACTOME SIGNALING BY NOTCH3	48	9.41e-01	-0.006190	9.85e-01
REACTOME ABACAVIR TRANSMEMBRANE TRANSPORT	5	9.42e-01	0.018900	9.85e-01
REACTOME AZATHIOPRINE ADME	22	9.42e-01	-0.009020	9.85e-01
REACTOME MULTIFUNCTIONAL ANION EXCHANGERS	9	9.43e-01	0.013800	9.85e-01
REACTOME CITRIC ACID CYCLE TCA CYCLE	21	9.43e-01	0.009010	9.85e-01
REACTOME NEGATIVE REGULATION OF NMDA RECEPTOR MEDIATED NEURONAL TRANSMISSION	20	9.44e-01	-0.009110	9.85e-01
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	20	9.44e-01	0.009080	9.85e-01
REACTOME MIRO GTPASE CYCLE	8	9.45e-01	0.014200	9.85e-01
REACTOME TRAFFICKING OF AMPA RECEPTORS	29	9.46e-01	-0.007300	9.86e-01
REACTOME REGULATION OF GENE EXPRESSION BY HYPOXIA INDUCIBLE FACTOR	11	9.47e-01	-0.011600	9.86e-01
REACTOME MINERALOCORTICOID BIOSYNTHESIS	6	9.47e-01	0.015600	9.86e-01
REACTOME DAP12 INTERACTIONS	37	9.48e-01	0.006190	9.86e-01
REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	13	9.48e-01	0.010400	9.86e-01
REACTOME INTERLEUKIN 1 PROCESSING	9	9.49e-01	-0.012400	9.86e-01
REACTOME REGULATION OF INSULIN SECRETION	77	9.49e-01	-0.004200	9.86e-01
REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	9	9.50e-01	0.012100	9.86e-01
REACTOME INTRA GOLGI TRAFFIC	43	9.51e-01	-0.005410	9.86e-01
REACTOME REGULATION OF GLYCOLYSIS BY FRUCTOSE 2 6 BISPHOSPHATE METABOLISM	11	9.52e-01	0.010400	9.86e-01
REACTOME NEGATIVE REGULATION OF TCF DEPENDENT SIGNALING BY WNT LIGAND ANTAGONISTS	15	9.52e-01	0.008920	9.86e-01
REACTOME HIV INFECTION	223	9.52e-01	-0.002320	9.86e-01
REACTOME INTERLEUKIN 35 SIGNALLING	12	9.53e-01	0.009730	9.86e-01
REACTOME POLYMERASE SWITCHING ON THE C STRAND OF THE TELOMERE	25	9.54e-01	-0.006630	9.86e-01
REACTOME PECAM1 INTERACTIONS	12	9.56e-01	-0.009260	9.86e-01
REACTOME RESOLUTION OF ABASIC SITES AP SITES	38	9.57e-01	-0.005080	9.86e-01
REACTOME SHC MEDIATED CASCADE FGFR1	21	9.57e-01	-0.006720	9.86e-01
REACTOME METABOLISM OF NITRIC OXIDE NOS3 ACTIVATION AND REGULATION	15	9.58e-01	0.007850	9.86e-01
REACTOME NGF STIMULATED TRANSCRIPTION	38	9.58e-01	0.004900	9.86e-01
REACTOME REGULATION OF BACH1 ACTIVITY	11	9.59e-01	0.009040	9.86e-01
REACTOME PYRIMIDINE CATABOLISM	12	9.59e-01	-0.008620	9.86e-01
REACTOME DEFECTS OF CONTACT ACTIVATION SYSTEM CAS AND KALLIKREIN KININ SYSTEM KKS	14	9.60e-01	0.007790	9.86e-01
REACTOME SIGNALING BY BMP	27	9.61e-01	-0.005500	9.86e-01
REACTOME FORMYL PEPTIDE RECEPTORS BIND FORMYL PEPTIDES AND MANY OTHER LIGANDS	8	9.61e-01	-0.010000	9.86e-01
REACTOME RET SIGNALING	40	9.62e-01	-0.004410	9.86e-01
REACTOME RAB GERANYLGERANYLATION	57	9.62e-01	-0.003690	9.86e-01
REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	10	9.62e-01	0.008760	9.86e-01
REACTOME UB SPECIFIC PROCESSING PROTEASES	187	9.62e-01	-0.002010	9.86e-01
REACTOME DEPOLYMERISATION OF THE NUCLEAR LAMINA	14	9.63e-01	-0.007130	9.87e-01
REACTOME INTERLEUKIN 12 SIGNALING	43	9.65e-01	0.003820	9.88e-01
REACTOME PTK6 REGULATES RTKS AND THEIR EFFECTORS AKT1 AND DOK1	9	9.66e-01	0.008210	9.88e-01
REACTOME BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS	10	9.68e-01	0.007320	9.90e-01
REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	11	9.68e-01	0.006890	9.90e-01
REACTOME FRUCTOSE METABOLISM	7	9.70e-01	0.008170	9.91e-01
REACTOME TRANSCRIPTION OF E2F TARGETS UNDER NEGATIVE CONTROL BY DREAM COMPLEX	19	9.73e-01	-0.004530	9.93e-01
REACTOME MISCELLANEOUS SUBSTRATES	12	9.73e-01	0.005580	9.93e-01
REACTOME TRANSCRIPTIONAL REGULATION OF TESTIS DIFFERENTIATION	12	9.75e-01	-0.005320	9.93e-01
REACTOME WNT5A DEPENDENT INTERNALIZATION OF FZD2 FZD5 AND ROR2	13	9.77e-01	0.004690	9.94e-01
REACTOME INTERLEUKIN 7 SIGNALING	31	9.77e-01	-0.002960	9.94e-01
REACTOME REGULATION OF KIT SIGNALING	16	9.77e-01	0.004120	9.94e-01
REACTOME RHOF GTPASE CYCLE	40	9.78e-01	0.002470	9.95e-01
REACTOME IRS ACTIVATION	5	9.79e-01	-0.006840	9.95e-01
REACTOME TRANSPORT OF FATTY ACIDS	8	9.82e-01	0.004720	9.96e-01
REACTOME TRANSPORT OF NUCLEOTIDE SUGARS	8	9.82e-01	-0.004690	9.96e-01
REACTOME TRANSLATION OF SARS COV 1 STRUCTURAL PROTEINS	29	9.83e-01	0.002230	9.96e-01
REACTOME HSP90 CHAPERONE CYCLE FOR STEROID HORMONE RECEPTORS SHR IN THE PRESENCE OF LIGAND	55	9.84e-01	-0.001560	9.96e-01
REACTOME INWARDLY RECTIFYING K CHANNELS	35	9.84e-01	0.001960	9.96e-01
REACTOME BETA OXIDATION OF OCTANOYL COA TO HEXANOYL COA	5	9.84e-01	0.005130	9.96e-01
REACTOME PTK6 EXPRESSION	5	9.86e-01	0.004640	9.97e-01
REACTOME GAP FILLING DNA REPAIR SYNTHESIS AND LIGATION IN GG NER	25	9.87e-01	-0.001860	9.98e-01
REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	18	9.88e-01	0.002130	9.98e-01
REACTOME ADAPTIVE IMMUNE SYSTEM	729	9.88e-01	0.000320	9.98e-01
REACTOME NECTIN NECL TRANS HETERODIMERIZATION	7	9.89e-01	-0.002880	9.98e-01
REACTOME POLYMERASE SWITCHING	13	9.90e-01	-0.002040	9.98e-01
REACTOME ABC TRANSPORTERS IN LIPID HOMEOSTASIS	17	9.91e-01	0.001580	9.98e-01
REACTOME DISEASES OF DNA REPAIR	51	9.92e-01	-0.000804	9.98e-01
REACTOME ACROSOME REACTION AND SPERM OOCYTE MEMBRANE BINDING	6	9.92e-01	0.002260	9.98e-01
REACTOME INTERLEUKIN 15 SIGNALING	13	9.93e-01	0.001320	9.98e-01
REACTOME LATE ENDOSOMAL MICROAUTOPHAGY	33	9.94e-01	-0.000814	9.98e-01
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	62	9.94e-01	-0.000556	9.98e-01
REACTOME NUCLEAR PORE COMPLEX NPC DISASSEMBLY	36	9.95e-01	0.000604	9.98e-01
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR2	29	9.96e-01	-0.000596	9.98e-01
REACTOME PLATELET SENSITIZATION BY LDL	17	9.96e-01	-0.000770	9.98e-01
REACTOME ACTIVATION OF CASPASES THROUGH APOPTOSOME MEDIATED CLEAVAGE	5	9.96e-01	-0.001240	9.98e-01
REACTOME OTHER SEMAPHORIN INTERACTIONS	18	9.96e-01	0.000627	9.98e-01
REACTOME HDL ASSEMBLY	8	9.97e-01	0.000716	9.98e-01
REACTOME MITOTIC G1 PHASE AND G1 S TRANSITION	145	9.98e-01	0.000150	9.98e-01
REACTOME SCAVENGING BY CLASS B RECEPTORS	6	9.98e-01	0.000545	9.98e-01

---

Detailed Gene set reports

REACTOME_OLFACTORY_SIGNALING_PATHWAY

REACTOME_OLFACTORY_SIGNALING_PATHWAY

	628
set	REACTOME_OLFACTORY_SIGNALING_PATHWAY
setSize	348
pANOVA	1e-18
s.dist	0.275
p.adjustANOVA	1.65e-15

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR5H1	9866
OR2T3	9842
OR10T2	9805
OR56A5	9794
OR5T3	9789
OR5T2	9775
OR8A1	9774
OR10J1	9773
OR6Q1	9767
OR8D4	9765
OR10S1	9734
OR4N2	9732
OR10G7	9726
OR2L3	9672
OR51L1	9661
OR5P2	9650
OR10AG1	9645
OR2AT4	9600
OR6C4	9574
OR2D3	9564

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR5H1	9866.0
OR2T3	9842.0
OR10T2	9805.0
OR56A5	9794.0
OR5T3	9789.0
OR5T2	9775.0
OR8A1	9774.0
OR10J1	9773.0
OR6Q1	9767.0
OR8D4	9765.0
OR10S1	9734.0
OR4N2	9732.0
OR10G7	9726.0
OR2L3	9672.0
OR51L1	9661.0
OR5P2	9650.0
OR10AG1	9645.0
OR2AT4	9600.0
OR6C4	9574.0
OR2D3	9564.0
OR10J5	9542.0
OR4A47	9531.0
OR2AK2	9523.0
OR5H6	9521.0
OR2L5	9505.0
OR6N2	9499.0
OR10J3	9494.0
OR1J4	9466.0
OR13C2	9460.0
OR5T1	9459.0
OR6C6	9455.0
OR52E4	9446.0
OR10G9	9443.0
OR56B1	9417.0
OR51A2	9375.0
OR51B2	9370.0
OR14C36	9365.0
OR7A5	9363.0
OR8S1	9354.0
OR2B6	9345.0
OR8D2	9339.0
OR6S1	9313.0
OR2J2	9304.0
OR52M1	9280.0
OR4D9	9279.0
OR1J1	9278.0
OR52R1	9272.0
OR6C76	9236.0
OR1I1	9176.0
OR51I1	9141.0
OR52I2	9138.0
OR5AC2	9134.0
OR1A1	9118.0
OR6K3	9098.0
OR8H3	9053.0
OR10W1	9050.0
OR1E2	9048.0
OR6C2	9017.0
OR52A1	9012.0
OR5AU1	8994.0
OR2M3	8986.0
OR51B6	8928.0
OR2A2	8881.0
OR5K1	8875.0
OR4K1	8855.0
OR2H2	8840.0
OR51B4	8834.0
OR5A1	8829.0
OR51A7	8821.0
OR6C3	8815.0
OR5B12	8800.0
OR2L2	8753.0
OR11L1	8690.0
OR10G2	8664.0
OR9A4	8643.0
OR2T27	8625.0
OR7D4	8618.0
OR10G3	8594.0
OR52E2	8584.0
OR1F1	8543.0
OR1N2	8521.0
OR51F1	8494.0
OR1N1	8479.0
OR14J1	8463.0
OR13F1	8416.0
OR5AK2	8409.0
OR1A2	8405.0
OR4X1	8336.0
OR6C1	8333.0
OR10G4	8330.0
OR2T6	8316.0
OR9K2	8300.0
OR1L4	8289.0
OR8B4	8197.0
OR4B1	8167.0
OR2T33	8142.0
OR2AG1	8129.0
OR11H6	8105.0
OR1J2	8054.0
OR13C3	8038.0
OR4X2	7999.0
OR10K1	7997.0
OR5K4	7953.0
OR12D3	7750.0
OR7C2	7734.0
OR13G1	7682.0
OR5V1	7680.0
OR6T1	7652.0
OR51G1	7618.0
OR1G1	7581.0
OR6C75	7580.0
OR56A4	7570.0
OR6C68	7506.0
OR8B8	7471.0
OR2M2	7381.0
OR4K14	7375.0
OR6N1	7300.0
OR51I2	7282.0
OR13C9	7173.0
OR56B4	7144.0
OR5H15	7123.0
OR10H4	7110.0
OR1L1	7075.0
OR10A2	7021.0
OR2T1	6947.0
OR8G5	6893.0
OR51B5	6793.0
OR6C70	6752.0
RTP2	6715.0
OR6C65	6501.0
OR4D6	6445.0
OR9Q1	6402.0
OR11G2	6370.0
OR8G1	6306.0
OR2B3	6299.0
OR8B2	6292.0
OR6B3	6241.0
OR13C4	6040.0
OR4K5	6014.0
OR13C8	5993.0
OR11A1	5987.0
EBF1	5985.0
OR10G8	5974.0
OR13A1	5906.0
OR10A3	5881.0
RTP1	5830.0
OR2AP1	5825.0
OR7G1	5777.0
OR6K2	5770.0
OR2T11	5760.0
OR10A5	5744.0
ANO2	5670.0
OR2G6	5530.0
OR2F1	5480.0
OR51S1	5436.0
OR4K13	5363.0
OR2C3	5279.0
OR4K17	5261.0
OR6V1	5257.0
OR2V1	5256.0
OR5AS1	5176.0
OR12D2	5169.0
REEP1	5149.0
OR4C45	5137.0
OR4D1	5110.0
OR2T12	5087.0
OR10A7	5054.0
OR52N1	5021.0
OR6X1	4999.0
OR5B3	4936.0
OR51T1	4914.0
OR5F1	4913.0
OR14A16	4836.0
OR56A1	4759.0
OR4D10	4721.0
LHX2	4707.0
OR2H1	4692.0
OR5P3	4674.0
OR2A5	4618.0
OR5D13	4606.0
OR6F1	4481.0
OR14I1	4386.0
OR6B1	4294.0
OR6C74	4219.0
OR2L13	4108.0
OR7C1	4041.0
OR52H1	3942.0
OR5D18	3930.0
OR4C12	3827.0
OR1Q1	3759.0
OR52K1	3588.0
OR4M1	3545.0
OR10K2	3149.0
OR5B21	3049.0
OR1B1	2990.0
OR8J3	2874.0
OR6P1	2799.0
OR10AD1	2793.0
OR4S1	2742.0
OR8D1	2639.0
OR51F2	2508.0
OR51M1	2353.0
OR2F2	2343.0
OR56A3	2177.0
OR6B2	2171.0
OR8I2	2072.0
OR10H5	1924.0
OR2W1	1624.0
OR8U1	1579.0
OR1E1	1543.0
OR2W3	875.0
OR7A10	654.0
OR2S2	545.0
OR10A4	514.0
OR7G2	458.0
OR52E6	406.0
OR8U3	383.0
OR5I1	381.0
OR10H1	378.0
OR2C1	203.0
OR51E2	84.0
OR8K5	14.0
OR5A2	-56.0
OR11H4	-100.0
OR1S1	-211.0
CNGB1	-426.0
OR4L1	-568.0
OR4K2	-574.0
OR2A12	-635.0
OR2Y1	-688.0
OR2T4	-715.0
OR9A2	-716.0
OR4C3	-1034.0
OR4D2	-1054.0
OR2A14	-1147.0
OR8K1	-1245.0
OR8B12	-1438.0
OR1L3	-1763.0
OR6A2	-1767.0
OR4A15	-1864.0
OR4D11	-1916.0
OR2M5	-2015.0
OR51D1	-2578.0
OR10H3	-2666.0
OR7A17	-2762.0
OR5L2	-2869.0
OR13D1	-2875.0
OR5D14	-2960.0
OR6Y1	-3338.0
OR8K3	-3543.0
OR2V2	-3670.0
OR4D5	-3845.0
LDB1	-3900.0
OR10C1	-4061.0
OR4C15	-4395.0
ADCY3	-4480.0
OR10X1	-4558.0
OR4C46	-4597.0
OR1L8	-4764.0
OR13J1	-4771.0
OR5AP2	-4789.0
GNAL	-4827.0
OR5J2	-4985.0
OR1D2	-5048.0
OR5H2	-5129.0
OR52B2	-5244.0
OR8H1	-5470.0
OR5AN1	-5494.0
OR52W1	-5551.0
GNG13	-5594.0
OR6M1	-5659.0
OR2K2	-5730.0
OR4C16	-5737.0
OR5M1	-5747.0
OR2L8	-6217.0
OR4A16	-6243.0
OR52E8	-6383.0
OR3A3	-6427.0
OR1S2	-6486.0
OR5M10	-6579.0
OR2D2	-6847.0
OR2G3	-6883.0
OR51E1	-6931.0
OR2B11	-6957.0
OR9G4	-7040.0
OR5D16	-7047.0
OR5M9	-7095.0
OR2G2	-7401.0
OR5M11	-7544.0
OR2Z1	-7639.0
OR8J1	-7731.0
OR2B2	-7776.0
OR6K6	-7812.0
OR9I1	-8012.0
OR9Q2	-8059.0
OR5L1	-8109.0
OR1L6	-8296.0
OR8U8	-8386.0
OR3A2	-8557.0
OR1C1	-8586.0
OR7D2	-8631.0
OR5W2	-8666.0
OR52D1	-8958.0
OR10V1	-8996.0
OR5AR1	-9009.0
OR4N5	-9033.0
OR52I1	-9094.0
OR52N2	-9142.0
OR4F15	-9363.0
OR4E2	-9366.0
OR52J3	-9369.0
OR3A1	-9423.0
OR5B2	-9630.0
OR2M4	-9637.0
OR2T8	-10008.0
OR5M3	-10083.0
OR10A6	-10206.0
OR9G1	-10241.5
OR9G9	-10241.5
OR2AG2	-10277.0
OR4F6	-10293.0
OR51G2	-10400.0
OR5K2	-10435.0
OR10Q1	-10436.0
OR5B17	-10574.0
OR51V1	-10596.0
OR4C6	-10603.0
OR7G3	-10605.0
OR52A5	-10758.0
OR2AE1	-10808.0
OR5C1	-10912.0
OR1M1	-10936.0
OR4K15	-10985.0
OR10Z1	-11069.0
OR51Q1	-11085.0
CNGA4	-11152.0
OR10P1	-11182.0
GNB1	-11404.0
OR52K2	-11445.0
OR10H2	-11705.0
OR52B6	-11802.0
OR4A5	-11904.0
OR5K3	-11935.0
OR5M8	-11987.0
OR52L1	-12055.0
OR2M7	-12070.0
OR7E24	-12078.0
OR1K1	-12112.0

---

REACTOME_SENSORY_PERCEPTION

REACTOME_SENSORY_PERCEPTION

	1581
set	REACTOME_SENSORY_PERCEPTION
setSize	555
pANOVA	4.69e-12
s.dist	0.172
p.adjustANOVA	3.85e-09

Top enriched genes

Top 20 genes

GeneID	Gene Rank
OR5H1	9866
OR2T3	9842
OR10T2	9805
OR56A5	9794
OR5T3	9789
OR5T2	9775
OR8A1	9774
OR10J1	9773
OR6Q1	9767
OR8D4	9765
LRRC52	9742
OR10S1	9734
OR4N2	9732
OR10G7	9726
OR2L3	9672
OR51L1	9661
GNGT1	9652
OR5P2	9650
OR10AG1	9645
OR2AT4	9600

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
OR5H1	9866.0
OR2T3	9842.0
OR10T2	9805.0
OR56A5	9794.0
OR5T3	9789.0
OR5T2	9775.0
OR8A1	9774.0
OR10J1	9773.0
OR6Q1	9767.0
OR8D4	9765.0
LRRC52	9742.0
OR10S1	9734.0
OR4N2	9732.0
OR10G7	9726.0
OR2L3	9672.0
OR51L1	9661.0
GNGT1	9652.0
OR5P2	9650.0
OR10AG1	9645.0
OR2AT4	9600.0
OR6C4	9574.0
OR2D3	9564.0
OR10J5	9542.0
OR4A47	9531.0
OR2AK2	9523.0
OR5H6	9521.0
OR2L5	9505.0
OR6N2	9499.0
OR10J3	9494.0
OR1J4	9466.0
OR13C2	9460.0
OR5T1	9459.0
OR6C6	9455.0
OR52E4	9446.0
OR10G9	9443.0
OR56B1	9417.0
OR51A2	9375.0
OR51B2	9370.0
OR14C36	9365.0
OR7A5	9363.0
OR8S1	9354.0
OR2B6	9345.0
OR8D2	9339.0
OR6S1	9313.0
OR2J2	9304.0
OR52M1	9280.0
OR4D9	9279.0
OR1J1	9278.0
OR52R1	9272.0
OR6C76	9236.0
OR1I1	9176.0
OR51I1	9141.0
OR52I2	9138.0
OR5AC2	9134.0
OR1A1	9118.0
OR6K3	9098.0
OTOP1	9064.0
OR8H3	9053.0
OR10W1	9050.0
OR1E2	9048.0
OR6C2	9017.0
OR52A1	9012.0
OR5AU1	8994.0
OTOGL	8989.0
OR2M3	8986.0
OR51B6	8928.0
OR2A2	8881.0
OR5K1	8875.0
OR4K1	8855.0
OR2H2	8840.0
OR51B4	8834.0
OR5A1	8829.0
OR51A7	8821.0
OR6C3	8815.0
OR5B12	8800.0
TAS2R30	8769.0
OR2L2	8753.0
TMIE	8733.0
OR11L1	8690.0
OR10G2	8664.0
OR9A4	8643.0
OR2T27	8625.0
OR7D4	8618.0
OR10G3	8594.0
OR52E2	8584.0
RBP3	8564.0
OR1F1	8543.0
OR1N2	8521.0
TMC2	8512.0
STRA6	8497.0
AKR1C1	8495.0
OR51F1	8494.0
OR1N1	8479.0
OR14J1	8463.0
OR13F1	8416.0
OR5AK2	8409.0
OR1A2	8405.0
OR4X1	8336.0
OR6C1	8333.0
OR10G4	8330.0
OR2T6	8316.0
SCN2A	8302.0
OR9K2	8300.0
OR1L4	8289.0
OR8B4	8197.0
GUCA1C	8185.0
OR4B1	8167.0
OR2T33	8142.0
OR2AG1	8129.0
OR11H6	8105.0
OR1J2	8054.0
OR13C3	8038.0
OR4X2	7999.0
OR10K1	7997.0
OR5K4	7953.0
TTR	7877.0
OR12D3	7750.0
OR7C2	7734.0
TAS2R7	7708.0
OR13G1	7682.0
OR5V1	7680.0
OR6T1	7652.0
TAS2R16	7628.0
OR51G1	7618.0
OR1G1	7581.0
OR6C75	7580.0
OR56A4	7570.0
OR6C68	7506.0
RETSAT	7484.0
OR8B8	7471.0
OR2M2	7381.0
OR4K14	7375.0
SNAP25	7342.0
RBP2	7321.0
OR6N1	7300.0
OR51I2	7282.0
RCVRN	7271.0
MYO3B	7213.0
OR13C9	7173.0
OR56B4	7144.0
OR5H15	7123.0
OR10H4	7110.0
OR1L1	7075.0
OR10A2	7021.0
APOC2	6982.0
FSCN2	6965.0
OR2T1	6947.0
OR8G5	6893.0
EPS8L2	6890.0
OR51B5	6793.0
OR6C70	6752.0
GUCA1A	6718.0
RTP2	6715.0
SCN3A	6640.0
AKR1B10	6588.0
TAS2R3	6526.0
SDC2	6516.0
OR6C65	6501.0
OR4D6	6445.0
OR9Q1	6402.0
OR11G2	6370.0
OR8G1	6306.0
OR2B3	6299.0
OR8B2	6292.0
OR6B3	6241.0
VAMP2	6211.0
CABP1	6197.0
ACTB	6120.0
GPC6	6070.0
OR13C4	6040.0
OR4K5	6014.0
OR13C8	5993.0
OR11A1	5987.0
EBF1	5985.0
OR10G8	5974.0
OR13A1	5906.0
OR10A3	5881.0
RLBP1	5858.0
RTP1	5830.0
OR2AP1	5825.0
TAS2R40	5788.0
OR7G1	5777.0
OR6K2	5770.0
OR2T11	5760.0
OR10A5	5744.0
SCN2B	5724.0
ANO2	5670.0
TAS2R10	5658.0
NMT2	5639.0
EPB41L1	5607.0
OR2G6	5530.0
KCNMB1	5507.0
OR2F1	5480.0
OR51S1	5436.0
MYO3A	5365.0
OR4K13	5363.0
PCDH15	5295.0
OR2C3	5279.0
OR4K17	5261.0
OR6V1	5257.0
OR2V1	5256.0
OR5AS1	5176.0
OR12D2	5169.0
RBP1	5155.0
REEP1	5149.0
OR4C45	5137.0
OR4D1	5110.0
LRP2	5099.0
OR2T12	5087.0
OR10A7	5054.0
OR52N1	5021.0
OR6X1	4999.0
CACNA1D	4950.0
OR5B3	4936.0
OR51T1	4914.0
OR5F1	4913.0
OR14A16	4836.0
ATP2B1	4824.0
USH1C	4820.0
OR56A1	4759.0
OR4D10	4721.0
LHX2	4707.0
OR2H1	4692.0
OR5P3	4674.0
EPS8	4632.0
OR2A5	4618.0
OR5D13	4606.0
OR6F1	4481.0
OR14I1	4386.0
OR6B1	4294.0
OR6C74	4219.0
SCN9A	4195.0
AKR1C4	4150.0
OR2L13	4108.0
CAMKMT	4105.0
CAPZB	4075.0
OR7C1	4041.0
OR52H1	3942.0
OR5D18	3930.0
OR4C12	3827.0
OR1Q1	3759.0
APOE	3745.0
RIPOR2	3741.0
GNAT3	3652.0
KCNMA1	3599.0
OR52K1	3588.0
PNLIP	3577.0
RDH12	3551.0
OR4M1	3545.0
SDC1	3508.0
TAS2R41	3453.0
CLPS	3365.0
SDC3	3360.0
GNB3	3259.0
METAP2	3181.0
OR10K2	3149.0
OR5B21	3049.0
OR1B1	2990.0
TAS2R14	2927.0
OR8J3	2874.0
OR6P1	2799.0
OR10AD1	2793.0
PRKCQ	2767.0
OR4S1	2742.0
OR8D1	2639.0
AKR1C3	2596.0
ACTG1	2573.0
OR51F2	2508.0
GRM4	2441.0
OR51M1	2353.0
OR2F2	2343.0
GPC1	2202.0
OR56A3	2177.0
OR6B2	2171.0
DHRS3	2161.0
APOB	2093.0
OR8I2	2072.0
SLC17A8	1984.0
XIRP2	1926.0
OR10H5	1924.0
PCLO	1827.0
TAS2R1	1725.0
ESPN	1669.0
OR2W1	1624.0
OR8U1	1579.0
OR1E1	1543.0
TAS2R46	1355.0
MYO7A	1283.0
SCN4B	1272.0
CNGA1	1216.0
TAS2R50	993.0
GPC5	914.0
WHRN	902.0
MYH9	883.0
OR2W3	875.0
OTOF	803.0
STRC	734.0
OR7A10	654.0
TRPM5	653.0
BSN	569.0
CAPZA1	546.0
OR2S2	545.0
OR10A4	514.0
OR7G2	458.0
OR52E6	406.0
OR8U3	383.0
OR5I1	381.0
OR10H1	378.0
OR2C1	203.0
TWF1	157.0
OR51E2	84.0
OR8K5	14.0
OR5A2	-56.0
OR11H4	-100.0
OR1S1	-211.0
RDX	-212.0
LRP10	-371.0
CNGB1	-426.0
OR4L1	-568.0
OR4K2	-574.0
OR2A12	-635.0
ABCA4	-639.0
CTBP2	-650.0
OR2Y1	-688.0
OR2T4	-715.0
OR9A2	-716.0
KCNN2	-815.0
GRK4	-836.0
RAB3A	-912.0
SDC4	-963.0
APOA1	-1006.0
OR4C3	-1034.0
OR4D2	-1054.0
LDLR	-1067.0
RDH10	-1109.0
OR2A14	-1147.0
OR8K1	-1245.0
TMC1	-1304.0
OR8B12	-1438.0
CACNB2	-1479.0
CLIC5	-1570.0
SPTBN1	-1621.0
OR1L3	-1763.0
OR6A2	-1767.0
PRKCA	-1822.0
STX1A	-1844.0
OR4A15	-1864.0
OR4D11	-1916.0
OR2M5	-2015.0
GRM1	-2054.0
AGRN	-2272.0
PDE6B	-2329.0
PJVK	-2370.0
RGS9BP	-2374.0
OR51D1	-2578.0
OR10H3	-2666.0
GPC2	-2714.0
LHFPL5	-2732.0
CACNA2D2	-2742.0
OR7A17	-2762.0
APOC3	-2790.0
GRXCR1	-2819.0
APOA4	-2820.0
SLC26A5	-2828.0
OR5L2	-2869.0
OR13D1	-2875.0
OR5D14	-2960.0
HSPG2	-3092.0
TPRN	-3103.0
TAS2R20	-3139.0
BCO1	-3153.0
CAPZA2	-3154.0
OTOG	-3210.0
TAS2R8	-3283.0
OR6Y1	-3338.0
KCNJ2	-3351.0
SCNN1D	-3408.0
FNTA	-3525.0
OR8K3	-3543.0
METAP1	-3546.0
USH1G	-3580.0
ATP2B2	-3623.0
OR2V2	-3670.0
EPB41L3	-3695.0
CIB2	-3749.0
CDH23	-3818.0
OR4D5	-3845.0
TAS1R1	-3847.0
LDB1	-3900.0
SCNN1G	-3918.0
TAS2R38	-4006.0
OR10C1	-4061.0
RDH5	-4200.0
GNAT1	-4244.0
GSN	-4251.0
PLS1	-4325.0
OR4C15	-4395.0
ADCY3	-4480.0
OR10X1	-4558.0
CYP4V2	-4577.0
ESPNL	-4585.0
OR4C46	-4597.0
RDH11	-4758.0
OR1L8	-4764.0
OR13J1	-4771.0
OR5AP2	-4789.0
SPTAN1	-4822.0
GNAL	-4827.0
RHO	-4906.0
PLB1	-4929.0
SCNN1B	-4969.0
OR5J2	-4985.0
RDH16	-5012.0
OR1D2	-5048.0
GUCY2D	-5049.0
SAG	-5099.0
OR5H2	-5129.0
LRP12	-5147.0
EZR	-5179.0
OR52B2	-5244.0
MYO1C	-5402.0
OR8H1	-5470.0
OR5AN1	-5494.0
OR52W1	-5551.0
GNG13	-5594.0
OR6M1	-5659.0
OR2K2	-5730.0
OR4C16	-5737.0
OR5M1	-5747.0
SCN1B	-5938.0
GNB5	-5958.0
RGS9	-6201.0
OR2L8	-6217.0
OR4A16	-6243.0
CALM1	-6248.0
OR52E8	-6383.0
OR3A3	-6427.0
NMT1	-6446.0
KCNQ4	-6471.0
OR1S2	-6486.0
OR5M10	-6579.0
LRP1	-6665.0
OR2D2	-6847.0
RDH8	-6875.0
PLCB2	-6878.0
OR2G3	-6883.0
OR51E1	-6931.0
OR2B11	-6957.0
OR9G4	-7040.0
OR5D16	-7047.0
TAS2R13	-7089.0
OR5M9	-7095.0
TAS1R2	-7190.0
GRK7	-7308.0
OR2G2	-7401.0
NAPEPLD	-7448.0
RBP4	-7458.0
OR5M11	-7544.0
RPE65	-7590.0
LRP8	-7638.0
OR2Z1	-7639.0
OR8J1	-7731.0
OR2B2	-7776.0
OR6K6	-7812.0
OR9I1	-8012.0
OR9Q2	-8059.0
OR5L1	-8109.0
LPL	-8225.0
OR1L6	-8296.0
OR8U8	-8386.0
OR3A2	-8557.0
SLC24A1	-8580.0
OR1C1	-8586.0
OR7D2	-8631.0
OR5W2	-8666.0
MYO15A	-8922.0
OR52D1	-8958.0
OR10V1	-8996.0
OR5AR1	-9009.0
OR4N5	-9033.0
TAS2R43	-9081.0
OR52I1	-9094.0
OR52N2	-9142.0
APOM	-9320.0
ITPR3	-9355.0
OR4F15	-9363.0
OR4E2	-9366.0
GRXCR2	-9368.0
OR52J3	-9369.0
TWF2	-9384.0
OR3A1	-9423.0
BCO2	-9523.0
SDR9C7	-9596.0
OR5B2	-9630.0
OR2M4	-9637.0
PDE6A	-9746.0
DNAJC5	-9767.0
TRIOBP	-9808.0
HSD17B1	-9927.0
FNTB	-9950.0
OR2T8	-10008.0
TAS2R31	-10052.0
OR5M3	-10083.0
CHRNA9	-10102.0
OR10A6	-10206.0
LRAT	-10226.0
TAS2R5	-10238.0
OR9G1	-10241.5
OR9G9	-10241.5
TAS2R39	-10244.0
OR2AG2	-10277.0
TAS1R3	-10291.0
OR4F6	-10293.0
DHRS9	-10324.0
OR51G2	-10400.0
APOA2	-10415.0
OR5K2	-10435.0
OR10Q1	-10436.0
GRK1	-10550.0
OR5B17	-10574.0
OR51V1	-10596.0
OR4C6	-10603.0
OR7G3	-10605.0
TRPM4	-10666.0
OPN1SW	-10718.0
CABP2	-10757.0
OR52A5	-10758.0
OR2AE1	-10808.0
OR5C1	-10912.0
OR1M1	-10936.0
PDE6G	-10970.0
OR4K15	-10985.0
OR10Z1	-11069.0
OR51Q1	-11085.0
CNGA4	-11152.0
OR10P1	-11182.0
HSD17B6	-11265.0
CALHM1	-11348.0
GNB1	-11404.0
GPIHBP1	-11428.0
OR52K2	-11445.0
TAS2R4	-11502.0
SCNN1A	-11633.0
OR10H2	-11705.0
CALHM3	-11775.0
GUCA1B	-11798.0
OR52B6	-11802.0
OR4A5	-11904.0
OR5K3	-11935.0
CHRNA10	-11946.0
OR5M8	-11987.0
OR52L1	-12055.0
OR2M7	-12070.0
OR7E24	-12078.0
OR1K1	-12112.0

---

REACTOME_KERATINIZATION

REACTOME_KERATINIZATION

	1073
set	REACTOME_KERATINIZATION
setSize	210
pANOVA	1.39e-08
s.dist	0.227
p.adjustANOVA	7.6e-06

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRTAP3-3	9853
KRTAP4-7	9828
LCE2D	9810
KRTAP4-6	9792
LCE3D	9787
KRTAP2-3	9756
KRTAP9-9	9751
KRTAP22-1	9690
KRTAP12-1	9671
KRTAP5-11	9669
KRT23	9635
LCE2C	9555
KRTAP9-4	9517
SPRR3	9509
KRTAP19-3	9464
KRTAP6-2	9458
KRTAP5-10	9420
DSC1	9388
KRTAP1-4	9380
KRTAP4-4	9358

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRTAP3-3	9853
KRTAP4-7	9828
LCE2D	9810
KRTAP4-6	9792
LCE3D	9787
KRTAP2-3	9756
KRTAP9-9	9751
KRTAP22-1	9690
KRTAP12-1	9671
KRTAP5-11	9669
KRT23	9635
LCE2C	9555
KRTAP9-4	9517
SPRR3	9509
KRTAP19-3	9464
KRTAP6-2	9458
KRTAP5-10	9420
DSC1	9388
KRTAP1-4	9380
KRTAP4-4	9358
IVL	9305
KRTAP9-3	9281
KRTAP10-5	9250
KRTAP19-1	9217
LCE4A	9194
KRTAP25-1	9167
LELP1	9165
DSG1	9164
KRT6C	9161
KRTAP21-3	9120
KRT76	9109
DSG4	9070
KRTAP4-5	9028
RPTN	9018
KRTAP5-7	8984
KRTAP4-8	8972
KRT14	8961
LCE1E	8959
KRTAP1-3	8953
KRTAP4-11	8948
KRTAP2-2	8944
SPINK5	8925
LCE6A	8910
KRTAP19-7	8857
KRT40	8851
KRTAP12-4	8705
KRTAP1-5	8659
SPRR2A	8605
SPRR2G	8604
KRTAP12-3	8489
KRTAP5-4	8480
KRT33A	8459
LCE1C	8396
KRT9	8384
KRT37	8352
KRTAP20-1	8308
KRT35	8285
KRT15	8274
KRTAP13-3	8073
PKP1	8071
KRTAP10-3	8016
KRT4	7998
LCE5A	7984
LIPK	7884
KRTAP9-2	7799
KRTAP2-1	7737
LCE1A	7697
KRTAP10-1	7499
CASP14	7494
KLK12	7384
LCE2A	7338
KRTAP6-3	7319
KRT75	7252
KRTAP21-2	7159
KRTAP9-6	7059
CDSN	7028
KRT19	6770
KRT86	6616
KRTAP6-1	6504
SPRR2E	6467
KRT38	6392
FLG	6382
LCE3B	6339
KRTAP21-1	6245
KRT39	6214
KRTAP10-10	6059
DSP	6013
KRTAP19-8	5907
KRTAP5-3	5768
SPRR2F	5606
KRTAP15-1	5251
KRTAP10-9	5083
SPRR1B	4916
PRSS8	4635
LCE3E	4347
KRT73	4327
DSG2	4141
KLK5	4003
KRT6B	3873
KRT83	3792
KRT32	3760
KRT74	3646
PCSK6	3622
ST14	3570
TCHH	3514
KRT10	3394
KRTAP3-1	2939
KRTAP4-2	2857
KRT16	2701
KAZN	2366
KRT2	2340
KRT7	2132
KRT79	2114
KRTAP13-2	2082
KRT82	1785
LCE1F	1720
KRTAP4-3	1540
KRTAP20-2	1321
KRT78	1035
KRTAP19-4	981
KRT5	900
PKP2	847
KRTAP4-1	785
PERP	556
KRT71	169
KRT81	85
KRT27	69
KRTAP10-7	25
KRTAP29-1	-32
DSG3	-96
KRTAP5-5	-169
KRTAP13-1	-218
SPRR2D	-453
KRT34	-802
KRTAP26-1	-939
SPINK6	-1077
SPINK9	-1195
KRTAP5-8	-1489
KRT84	-1909
KLK13	-2196
KRT1	-2327
KRTAP5-6	-2372
KRTAP10-4	-2638
KRTAP19-6	-2991
KRT3	-3230
KRTAP5-9	-3365
LCE1B	-3754
KRTAP8-1	-3867
KRT28	-3998
KRT20	-4101
KRTAP10-6	-4233
LIPN	-4310
KRTAP24-1	-4380
KRT72	-4429
PI3	-4967
PKP4	-5476
KRTAP27-1	-5518
LCE2B	-5524
KRTAP23-1	-6048
KRT77	-6341
JUP	-6376
KRTAP10-11	-6442
SPRR1A	-6506
CAPN1	-6557
KRTAP19-5	-7106
KRT24	-7484
LIPM	-7485
CAPNS1	-7520
KRTAP13-4	-7651
KRTAP11-1	-7785
KRT80	-7979
LIPJ	-8149
CELA2A	-8318
KRTAP10-12	-8414
KRT18	-8633
DSC2	-8635
TGM5	-8709
KLK8	-8791
KRT85	-8858
KRT13	-8991
KRTAP10-8	-9130
PKP3	-9260
KRT31	-9436
KRTAP16-1	-9460
EVPL	-9533
KRT6A	-9538
KRTAP2-4	-9765
KRTAP5-2	-9886
KLK14	-9911
DSC3	-9944
KRT36	-10001
KRTAP3-2	-10088
KRTAP19-2	-10453
KRT12	-10567
KRTAP5-1	-10585
KRT26	-10650
KRTAP9-1	-10721
CSTA	-10905
PPL	-10978
KRT33B	-11005
KRT8	-11273
KRTAP17-1	-11386
KRT17	-11412
KRTAP1-1	-11448
FURIN	-11533
LCE3A	-11590
TGM1	-11599
KRT25	-11842
KRTAP12-2	-11949
KRTAP10-2	-12006

---

REACTOME_NEUTROPHIL_DEGRANULATION

REACTOME_NEUTROPHIL_DEGRANULATION

	1053
set	REACTOME_NEUTROPHIL_DEGRANULATION
setSize	460
pANOVA	1.39e-06
s.dist	-0.131
p.adjustANOVA	0.000571

Top enriched genes

Top 20 genes

GeneID	Gene Rank
S100P	-12027
AZU1	-12019
RNASE3	-11878
RAB44	-11827
FCGR3B	-11819
PTAFR	-11765
DGAT1	-11754
TYROBP	-11723
FCER1G	-11663
LYZ	-11609
RNASE2	-11591
NBEAL2	-11526
CAMP	-11486
TARM1	-11418
HP	-11347
DPP7	-11345
SURF4	-11331
DNAJC3	-11234
AGPAT2	-11181
GUSB	-11178

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
S100P	-12027
AZU1	-12019
RNASE3	-11878
RAB44	-11827
FCGR3B	-11819
PTAFR	-11765
DGAT1	-11754
TYROBP	-11723
FCER1G	-11663
LYZ	-11609
RNASE2	-11591
NBEAL2	-11526
CAMP	-11486
TARM1	-11418
HP	-11347
DPP7	-11345
SURF4	-11331
DNAJC3	-11234
AGPAT2	-11181
GUSB	-11178
SERPINB1	-11169
ADGRG3	-11161
S100A9	-11144
SIGLEC14	-11128
TRPM2	-11109
CLEC4C	-11066
TIMP2	-11060
OSCAR	-11038
CYB5R3	-11017
RHOA	-10972
ADAM8	-10957
CREG1	-10934
CTSZ	-10925
UNC13D	-10890
ITGB2	-10882
MVP	-10840
GRN	-10837
AP1M1	-10791
CD63	-10781
FOLR3	-10780
CTSG	-10716
PLD1	-10696
PGLYRP1	-10690
B4GALT1	-10659
CTSD	-10656
SLPI	-10614
MS4A3	-10546
CANT1	-10524
PFKL	-10519
CXCR2	-10515
CLEC12A	-10513
KCNAB2	-10450
CEACAM3	-10448
STK10	-10434
AP2A2	-10414
MGST1	-10399
RETN	-10296
ALAD	-10253
SLC15A4	-10250
FCGR2A	-10113
LTA4H	-10086
TOLLIP	-10076
ATP8B4	-10072
FUCA2	-10049
CYFIP1	-10047
DSN1	-10041
PSMD2	-10038
TICAM2	-10025
DOK3	-10015
QSOX1	-9988
C3	-9967
MNDA	-9954
CD300A	-9936
FPR2	-9903
TNFAIP6	-9902
ARL8A	-9896
SYNGR1	-9858
PDAP1	-9833
LAMP1	-9778
PPIE	-9776
DNAJC5	-9767
MMP25	-9738
ATP6V0C	-9699
GLIPR1	-9684
OLR1	-9612
TCIRG1	-9603
CHIT1	-9593
ACLY	-9570
IMPDH1	-9440
NRAS	-9345
AMPD3	-9281
PRG3	-9265
LPCAT1	-9234
PDXK	-9201
PYGB	-9165
GAA	-9160
PRDX6	-9103
ACTR1B	-9089
CTSB	-9029
ALOX5	-9020
BST2	-8975
RAB4B	-8972
CR1	-8956
ATP11A	-8950
CAB39	-8881
TMEM30A	-8841
SERPINA1	-8752
IGF2R	-8732
NCSTN	-8683
PTPRJ	-8552
CD59	-8454
NCKAP1L	-8389
ANPEP	-8360
C5AR1	-8334
CD14	-8233
ORM2	-8232
LTF	-8229
RHOG	-8185
ROCK1	-8181
RAB5C	-8174
PSMB7	-8167
CEACAM8	-8126
VAT1	-8057
VCP	-8043
RAB27A	-7978
PLAC8	-7912
PRKCD	-7879
NAPRT	-7876
GALNS	-7824
LILRB2	-7819
CRACR2A	-7810
DYNC1H1	-7804
EPX	-7755
HBB	-7751
MAPK1	-7647
COMMD3	-7577
TCN1	-7546
PRG2	-7539
SCAMP1	-7469
SERPINB6	-7444
PAFAH1B2	-7323
TXNDC5	-7289
S100A11	-7211
KCMF1	-7182
STK11IP	-7085
ITGAL	-7046
ITGAX	-6960
CXCR1	-6925
TLR2	-6741
GYG1	-6710
RAP1B	-6680
DBNL	-6651
CAPN1	-6557
NHLRC3	-6542
PTGES2	-6477
ARMC8	-6444
S100A8	-6408
EEF2	-6398
JUP	-6376
AOC1	-6367
SLC27A2	-6309
IQGAP2	-6291
CAND1	-6264
CD68	-6250
CD58	-6215
LGALS3	-6179
CPNE1	-6092
GLB1	-6067
HVCN1	-6058
CFD	-6051
ATG7	-6042
NEU1	-6004
RAB18	-5919
ACTR2	-5826
GCA	-5768
CTSA	-5671
SERPINB10	-5627
DDOST	-5593
TNFRSF1B	-5582
LAMTOR1	-5574
AGL	-5511
RAC1	-5471
ALDOA	-5349
PSMD13	-5161
ORMDL3	-5153
SIGLEC9	-5087
BRI3	-5052
SNAP29	-5043
HEBP2	-4914
TMBIM1	-4901
RAB14	-4878
STOM	-4867
C1orf35	-4848
SPTAN1	-4822
CXCL1	-4817
CD93	-4727
GSTP1	-4595
ADA2	-4554
C6orf120	-4533
CKAP4	-4522
PLAU	-4491
RAB24	-4350
PSMD1	-4322
IQGAP1	-4277
GSN	-4251
TRAPPC1	-4197
RAB5B	-4193
GSDMD	-4074
VAMP8	-4047
ADGRE3	-4041
CAP1	-3968
SELL	-3929
PRSS3	-3781
BPI	-3751
GM2A	-3713
S100A7	-3643
DYNC1LI1	-3617
PTX3	-3531
HMOX2	-3482
DOCK2	-3481
DIAPH1	-3476
IST1	-3419
ITGAV	-3056
RAB10	-3046
IRAG2	-3035
ACAA1	-3023
SLC2A5	-2896
MPO	-2851
ARSB	-2835
ARHGAP45	-2786
CAT	-2776
PTPRN2	-2731
FGL2	-2725
MANBA	-2686
NPC2	-2608
ITGAM	-2602
PLEKHO2	-2565
ELANE	-2542
CTSS	-2453
ALDOC	-2424
ADGRE5	-2346
KRT1	-2327
PSMA5	-2270
P2RX1	-2250
FAF2	-2238
UBR4	-2210
PRTN3	-2183
HEXB	-2179
PYCARD	-2170
CMTM6	-2149
PTPN6	-2123
RAB37	-2035
ANXA2	-1995
NME2	-1941
RAB7A	-1836
SLC11A1	-1795
CRISPLD2	-1752
STING1	-1684
FGR	-1652
PLAUR	-1650
ATP11B	-1613
CHI3L1	-1611
KPNB1	-1610
MAPK14	-1601
SIRPA	-1592
CEACAM1	-1490
SLC44A2	-1352
DNAJC13	-1325
STBD1	-1269
CLEC4D	-1234
VCL	-1222
HSPA1B	-1221
HPSE	-1210
PSMD6	-1201
CCT2	-1182
CRISP3	-1162
TMEM63A	-1158
DYNLT1	-1027
CD177	-937
RAB3A	-912
ATAD3B	-888
ABCA13	-778
VNN1	-770
CLEC5A	-762
HSPA8	-751
ALDH3B1	-747
HK3	-656
PGM2	-621
CYBA	-592
CYSTM1	-546
CD53	-413
PKM	-362
DERA	-315
RAB6A	-286
LILRA3	-261
APRT	-231
XRCC5	-187
ARSA	-175
PGM1	-160
SIRPB1	-138
RAB31	-104
GPI	-34
ANO6	-6
DYNLL1	26
PGAM1	27
FABP5	133
VAPA	159
CPNE3	235
TMEM179B	285
ATP6V0A1	425
PSMC3	511
SRP14	550
HSP90AA1	563
LAIR1	590
A1BG	674
ACP3	698
CST3	792
FUCA1	820
ATP8A1	838
GGH	1039
CEP290	1087
CPPED1	1126
APEH	1295
ORM1	1366
TUBB	1394
SDCBP	1468
PSMD12	1473
CHRNB4	1643
LRRC7	1862
CSNK2B	1887
MAN2B1	1897
RAP1A	2073
COTL1	2089
PYGL	2090
PSMD11	2103
ATP6V1D	2216
HSP90AB1	2253
PRCP	2258
ASAH1	2304
YPEL5	2322
VPS35L	2341
CTSH	2500
BST1	2539
ENPP4	2549
HLA-A	2617
GMFG	2695
ARHGAP9	2729
EEF1A1	2745
HMGB1	2754
HGSNAT	2884
QPCT	2907
COMMD9	2910
MLEC	3021
NFKB1	3151
PIGR	3223
CSTB	3247
AHSG	3250
TSPAN14	3285
PSMD14	3291
PSAP	3410
RAP2B	3413
TMC6	3469
PPIA	3479
PSMD3	3550
RHOF	3620
FCAR	3707
PSMA2	3743
LAMTOR2	3777
CD36	3843
APAF1	3974
XRCC6	4006
LRG1	4106
CDA	4129
NFAM1	4278
PSMD7	4369
IMPDH2	4456
ARG1	4473
RAB3D	4535
OSTF1	4627
FTL	4671
SERPINA3	4743
ERP44	4757
GPR84	4929
SLC2A3	4940
FLG2	5049
ARPC5	5098
CTSC	5130
ADAM10	5192
DEGS1	5324
C3AR1	5455
GNS	5528
ILF2	5562
PSMB1	5600
GHDC	5627
HSPA6	5708
NFASC	5911
CDK13	5930
TOM1	5937
BIN2	5969
DSP	6013
PA2G4	6219
CD55	6247
CCT8	6338
SLCO4C1	6399
PTPRB	6460
PNP	6479
CD44	6533
NIT2	6615
MME	6617
B2M	6679
COPB1	6688
ACTR10	6689
PSEN1	6700
AGA	6756
RNASET2	6772
GOLGA7	6782
PPBP	7177
NDUFC2	7216
CNN2	7257
HLA-C	7317
TUBB4B	7335
SVIP	7336
SNAP25	7342
LCN2	7692
IDH1	7698
HLA-B	7828
FTH1	7833
TTR	7877
SNAP23	7885
PECAM1	7966
PKP1	8071
CD47	8141
PSMC2	8147
MIF	8239
FCN1	8247
FRK	8262
PADI2	8309
GDI2	8312
MMP9	8323
FPR1	8456
LAMTOR3	8466
PTPRC	8483
HSPA1A	8559
SIGLEC5	8670
SERPINB12	8853
HRNR	8877
MMP8	8935
MCEMP1	9148
DSG1	9164
LILRB3	9171
SERPINB3	9302
MGAM	9347
DSC1	9388
OLFM4	9404
S100A12	9525
DEFA4	9539
CALML5	9573
TBC1D10C	9599
CD33	9673
CEACAM6	9736

---

REACTOME_METABOLISM_OF_LIPIDS

REACTOME_METABOLISM_OF_LIPIDS

	880
set	REACTOME_METABOLISM_OF_LIPIDS
setSize	709
pANOVA	4.41e-06
s.dist	-0.101
p.adjustANOVA	0.00145

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FITM1	-11993
GDPD3	-11964
SMPD4	-11940
HSD3B7	-11906
PLA2G4B	-11895
DGAT1	-11754
PISD	-11623
SCAP	-11614
MOGAT2	-11554
ELOVL3	-11539
PNPLA2	-11444
LSS	-11419
CYP21A2	-11410
ARF1	-11363
GPD1	-11352
SREBF1	-11280
SLC27A5	-11268
AGPAT3	-11261
MFSD2A	-11240
AGPAT2	-11181

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FITM1	-11993
GDPD3	-11964
SMPD4	-11940
HSD3B7	-11906
PLA2G4B	-11895
DGAT1	-11754
PISD	-11623
SCAP	-11614
MOGAT2	-11554
ELOVL3	-11539
PNPLA2	-11444
LSS	-11419
CYP21A2	-11410
ARF1	-11363
GPD1	-11352
SREBF1	-11280
SLC27A5	-11268
AGPAT3	-11261
MFSD2A	-11240
AGPAT2	-11181
PTGDS	-11163
CERS3	-11124
HSD17B7	-11006
TSPOAP1	-11002
CRAT	-10960
CARM1	-10948
CSNK1G2	-10944
OSBPL2	-10887
GPX2	-10812
LTC4S	-10778
CERS2	-10753
THEM5	-10731
APOA5	-10728
INPP5D	-10722
CYP17A1	-10715
CYP11B1	-10709
NCOR2	-10707
INPP5E	-10700
PLD1	-10696
CHKB	-10634
SYNJ2	-10589
PGS1	-10563
ABCC1	-10504
GBA1	-10478
SGMS2	-10461
ACSF3	-10430
APOA2	-10415
HACD1	-10384
RXRA	-10375
ACSBG1	-10316
NEU2	-10268
PTGS2	-10240
SREBF2	-10197
FADS1	-10179
GGT5	-10147
SBF1	-10143
LTA4H	-10086
CIDEC	-9977
HSD17B1	-9927
OSBPL5	-9875
PRKACA	-9870
MCAT	-9782
CREBBP	-9764
MED25	-9704
HMGCS1	-9702
GLIPR1	-9684
ELOVL4	-9666
PTPMT1	-9661
PLA2G2D	-9631
VAC14	-9611
SLC10A1	-9608
MVD	-9581
PPARA	-9572
ACLY	-9570
SLC25A1	-9545
LIPE	-9542
ACACB	-9522
CYP11A1	-9504
CSNK2A2	-9451
MED26	-9449
ACAT1	-9352
PNPLA7	-9322
GGT1	-9308
GDE1	-9271
ACOX3	-9255
LPCAT1	-9234
PLEKHA2	-9223
CYP4F2	-9208
PLA2G15	-9206
DEGS2	-9199
FASN	-9192
PLD3	-9178
SLC51A	-9148
PTGES	-9144
FDX2	-9111
DPEP1	-9087
CPT1A	-9084
SQLE	-9083
ESYT1	-9061
DECR2	-9052
ALOX5	-9020
ACOT7	-9003
UBE2I	-8988
NRF1	-8974
PCYT2	-8923
ACADS	-8912
ACADL	-8902
PPARD	-8871
INSIG1	-8838
INPP4B	-8826
ACAD10	-8822
MECR	-8820
FAR2	-8816
MBTPS1	-8808
GBA2	-8803
ELOVL5	-8758
SRD5A3	-8754
PLD6	-8699
PPT1	-8678
MED8	-8677
CHKA	-8672
PLA2G6	-8669
CYP4F3	-8655
INPPL1	-8610
MAPKAPK2	-8608
ARF3	-8585
CERS6	-8499
PIK3R1	-8469
ARSI	-8459
CYP27B1	-8437
MTMR3	-8423
ELOVL1	-8416
MTMR12	-8402
OSBPL7	-8394
MED7	-8384
ACAA2	-8320
STARD10	-8283
MTF1	-8251
ALDH3B2	-8239
TXNRD1	-8203
PLAAT5	-8168
SPNS2	-8164
PIP5K1C	-8119
LGMN	-8097
TNFAIP8L1	-8060
THRAP3	-7980
TPTE	-7969
OSBPL9	-7939
PMVK	-7938
SUMF1	-7891
MBOAT2	-7726
PRKAG2	-7718
STAR	-7556
PLA2G12A	-7517
GDPD5	-7508
MED31	-7479
ACOX2	-7477
PLIN2	-7471
B3GALNT1	-7457
BDH1	-7455
HMGCL	-7454
SMPD1	-7453
ELOVL2	-7442
MED27	-7424
LIPH	-7423
DGAT2	-7371
SLC51B	-7310
PPP1CC	-7284
GPX4	-7245
INPP5K	-7218
SGMS1	-7192
G0S2	-7162
ACBD7	-7123
ETNK2	-7080
MED1	-7048
PIP4K2B	-7031
FADS2	-7026
PTDSS1	-7021
SIN3B	-7010
PTGS1	-6919
LPCAT3	-6901
DECR1	-6852
GGPS1	-6842
GRHL1	-6813
SLCO1A2	-6777
SAMD8	-6759
PITPNB	-6726
CERK	-6667
ALOX12B	-6655
LHB	-6642
PIK3R5	-6616
UGT8	-6548
PPARGC1B	-6514
CPT1B	-6493
PTGES2	-6477
MED17	-6473
DBI	-6453
HPGD	-6416
FIG4	-6400
SLC27A1	-6374
SERPINA6	-6373
HDAC3	-6372
SPHK2	-6371
SLC27A2	-6309
PCCB	-6305
PIK3R2	-6257
INSIG2	-6245
PRKD2	-6218
ACHE	-6174
IDI2	-6134
CHPT1	-6121
CPNE1	-6092
TMEM86B	-6076
GLB1	-6067
ACACA	-6054
TRIB3	-6043
CERS5	-6021
NEU1	-6004
PIAS4	-5999
PI4K2A	-5982
ALOX12	-5934
CYP4F22	-5893
ACOT1	-5882
HMGCLL1	-5877
STARD3	-5802
RAB4A	-5793
NUDT19	-5767
PITPNM2	-5762
ACER3	-5728
HADHB	-5692
PLPP6	-5677
CTSA	-5671
PNPLA8	-5622
ECHS1	-5611
TSPO	-5558
HELZ2	-5553
PLEKHA6	-5540
HPGDS	-5458
LPCAT2	-5445
MMAA	-5404
LPCAT4	-5372
CSNK2A1	-5317
TNFAIP8L2	-5251
PI4KA	-5250
INPP4A	-5219
ACSM3	-5209
PLPP1	-5167
ABCC3	-5165
PNPLA6	-5164
ORMDL3	-5153
SEC24B	-5148
GPAT4	-5113
ESRRA	-5111
PLD2	-5090
MED23	-5081
SPTSSA	-5057
PI4KB	-5010
SLC22A5	-4976
PITPNM1	-4971
MED13L	-4962
PLB1	-4929
SACM1L	-4926
ACSL1	-4910
GPD2	-4908
RAB14	-4878
ECI2	-4865
CHAT	-4854
HSD17B12	-4843
B4GALNT1	-4793
DHCR7	-4749
NR1H2	-4713
HSD11B2	-4699
CPT2	-4693
STARD4	-4687
CPTP	-4661
VAPB	-4633
BMAL1	-4632
PON2	-4602
DDHD2	-4592
PLA2G4F	-4523
ACBD5	-4475
HMGCS2	-4466
FAM120B	-4457
SGPP1	-4435
CYP4F8	-4420
ACSL3	-4353
PTDSS2	-4341
NCOA3	-4313
MED19	-4280
MMUT	-4265
CDK19	-4242
ASAH2	-4241
LPIN1	-4232
CYP2D6	-4218
CYP51A1	-4187
SCD	-4167
SEC24C	-4094
SPTLC2	-4082
HEXA	-4063
SRD5A1	-4039
PCCA	-4000
MBOAT1	-3974
PIK3R6	-3963
MED24	-3953
OSBPL8	-3920
MED21	-3892
MIGA2	-3870
PLD4	-3831
ACSS3	-3803
ALOX15B	-3774
MED6	-3752
GM2A	-3713
EP300	-3709
SLC27A3	-3686
GALC	-3684
AKR1C2	-3578
LPIN2	-3566
FDX1	-3548
PECR	-3540
LPIN3	-3530
ALAS1	-3526
NR1D1	-3520
GPD1L	-3477
CGA	-3466
PLEKHA8	-3458
ARSK	-3403
TGS1	-3371
CYP1A2	-3364
ESYT2	-3349
MTMR7	-3332
PIK3C2B	-3287
INPP5F	-3285
NFYA	-3268
PIK3CB	-3260
HSD17B11	-3257
CBR4	-3243
PLA2G2A	-3175
PLA2G2E	-3128
SGPL1	-3093
AACS	-3078
PLA2G4D	-3038
ACAA1	-3023
AGPAT4	-3008
ABHD3	-2981
FAR1	-2965
LBR	-2962
ABCB11	-2958
STARD6	-2934
CDS2	-2932
PRXL2B	-2927
ABHD4	-2925
PLA2G1B	-2921
PLEKHA5	-2910
NEU4	-2846
GNPAT	-2841
OXCT1	-2839
ARSB	-2835
PLIN3	-2830
CRLS1	-2811
ACOT11	-2788
PIK3C3	-2764
PTPN13	-2670
FAAH	-2651
ACER2	-2617
PIK3CG	-2606
FITM2	-2532
ACSL5	-2521
SLC44A4	-2512
CYP27A1	-2491
CHD9	-2377
CYP2U1	-2364
LDLRAP1	-2324
OSBPL1A	-2313
CUBN	-2307
FA2H	-2303
FABP3	-2264
PLBD1	-2245
AGPAT5	-2235
NR1H3	-2192
HEXB	-2179
PPP1CA	-2151
VDR	-2141
SEC24D	-2117
NCOA2	-2061
HADHA	-1978
CIDEA	-1937
PTGR2	-1930
GLB1L	-1895
GPAT2	-1873
PLEKHA1	-1871
GLTP	-1800
ACOT8	-1799
PI4K2B	-1772
ENPP7	-1762
PLA2R1	-1747
ARNT	-1688
MED9	-1667
SMPD3	-1666
KPNB1	-1610
HSD17B13	-1603
HACL1	-1563
EHHADH	-1526
CERS1	-1506
SLC25A17	-1487
ALOX5AP	-1467
PEMT	-1427
ARSG	-1418
STARD7	-1377
ACOT13	-1363
SLC44A2	-1352
ACOT12	-1329
PPM1L	-1272
TBL1XR1	-1268
CYP4B1	-1264
GPS2	-1263
NFYC	-1144
SPHK1	-1134
FABP4	-1123
PLAAT1	-1121
CEPT1	-1118
ME1	-1114
MVK	-1076
FHL2	-1046
APOA1	-1006
FDPS	-955
MSMO1	-920
ACOT6	-892
HMGCR	-848
SCP2	-843
HAO2	-810
MTMR4	-776
HSD3B2	-761
ALDH3B1	-747
ACSF2	-743
ACAD11	-724
NCOA6	-687
PLA1A	-633
MED22	-622
MTMR9	-611
CERS4	-606
ALPI	-545
SBF2	-536
GK2	-512
HACD2	-511
LCLAT1	-496
MLYCD	-366
MGLL	-292
ESYT3	-259
SPTSSB	-232
SUMO2	-224
TECR	-193
SYNJ1	-178
ARSA	-175
PLA2G4C	-80
RXRB	-77
TECRL	-73
FDFT1	-19
ACER1	37
FABP5	133
PLEKHA4	154
VAPA	159
HACD3	184
SRD5A2	201
ACADVL	212
DDHD1	217
CYP1B1	231
CPNE3	235
CROT	238
ETNK1	257
MTMR14	298
PCYT1A	331
PIP5K1A	335
ALDH3A2	347
NDUFAB1	369
ECI1	380
THRSP	419
PIP4P1	461
PEX11A	462
PLEKHA3	479
ACSBG2	532
PPARG	544
PIK3R4	631
TNFRSF21	669
HSD17B14	673
CYP2E1	676
ETNPPL	721
RUFY1	727
MED13	879
OSBP	946
SEC23A	1053
THEM4	1054
CERT1	1093
ELOVL7	1103
NFYB	1122
GPX1	1181
SC5D	1224
PPP1CB	1227
PHYH	1242
NEU3	1259
ACP6	1266
PLPP3	1285
CLOCK	1292
PIP4K2A	1306
BDH2	1310
RGL1	1446
AHR	1457
MED18	1647
PIP5K1B	1695
SMARCD3	1713
MCEE	1714
CYP39A1	1752
PTGR1	1766
PLAAT3	1820
CSNK2B	1887
CPNE6	1915
AGPAT1	2004
PIK3CA	2017
UGCG	2020
SCD5	2075
NCOR1	2130
MBOAT7	2137
STARD3NL	2152
PRKAA2	2223
PLA2G4A	2243
PTEN	2245
ASAH1	2304
CDS1	2320
GPCPD1	2338
CYP2R1	2532
ABCA1	2567
TM7SF2	2578
AKR1C3	2596
SIN3A	2603
PIK3C2A	2634
NCOA1	2647
PTGES3	2667
LPGAT1	2703
HSD17B3	2714
CDIPT	2722
ACSM6	2730
PRKD3	2775
CYP2J2	2860
ACOX1	2896
TBXAS1	2937
HADH	2988
ELOVL6	3026
MTMR6	3027
ACOT2	3045
CPNE7	3085
NR1H4	3110
DPEP2	3140
SPTLC1	3189
ACOXL	3206
MED30	3257
PLA2G4E	3334
PSAP	3410
DHRS7B	3411
ARSJ	3502
SUMF2	3509
RAN	3537
SAR1B	3547
SULT2A1	3679
MTMR2	3687
GSTM4	3688
PPARGC1A	3706
ABCB4	3716
BAAT	3723
CD36	3843
GDPD1	3859
PLAAT4	3914
MED10	3991
ACOT4	4029
TIAM2	4047
HSD17B4	4053
ALOXE3	4079
RORA	4123
AKR1C4	4150
ANGPTL4	4163
OSBPL10	4165
MED20	4245
MORC2	4247
AGPS	4272
PIK3R3	4324
ACBD6	4331
MED16	4350
ALB	4370
CYP19A1	4396
SELENOI	4483
ORMDL1	4487
AMACR	4589
PCTP	4601
MTMR10	4619
ABHD5	4631
PNPLA5	4657
PTGIS	4753
CCNC	4769
ACBD4	4822
MIGA1	4845
IDI1	4847
PIK3C2G	4876
KDSR	4879
ACADM	4900
ARNT2	4944
OSBPL3	5048
AKR1B1	5059
SLC44A1	5089
PHOSPHO1	5096
LRP2	5099
AGK	5106
PITPNM3	5139
SP1	5167
PPT2	5181
UGT1A9	5210
INPP5J	5214
FDXR	5229
MED28	5231
POMC	5282
DEGS1	5324
PON3	5337
AGMO	5384
MOGAT1	5432
RAB5A	5433
FABP7	5470
NUDT7	5511
ACAT2	5517
SLC44A3	5523
PRKAB2	5526
FABP9	5567
TNFAIP8L3	5656
PNPLA3	5711
CDK8	5803
ARV1	5846
SLC44A5	5859
CYP24A1	5882
AGT	5893
SGPP2	5920
BCHE	5967
TNFAIP8	6009
PIK3CD	6010
CH25H	6116
SLCO1B3	6125
PIKFYVE	6155
PRKD1	6170
MED29	6254
ENPP6	6279
CBR1	6313
SLCO1B1	6349
NPAS2	6411
ACSL6	6437
PRKACB	6462
OLAH	6503
CYP4F11	6534
DPEP3	6636
GC	6683
PLIN1	6734
LIPI	6739
SLC25A20	6755
AKR1D1	6795
FABP12	6812
MED15	6831
HSD11B1	6848
SEC24A	6864
PIP4K2C	6872
HSD3B1	7105
CYP7B1	7142
HSD17B2	7178
ORMDL2	7237
OSBPL6	7295
PLA2G3	7310
HILPDA	7328
CYP4A11	7433
PRKACG	7445
DHCR24	7458
EPHX2	7478
AKR1B15	7655
CYP7A1	7716
ALOX15	7719
MED4	7772
CYP1A1	7913
MOGAT3	7914
CYP46A1	7934
PLAAT2	8134
HSD17B8	8178
GPAM	8224
CAV1	8260
SPTLC3	8270
PLPP2	8317
CYP2C8	8325
FABP1	8379
SMPD2	8408
HACD4	8460
TPTE2	8482
PLA2G10	8487
AKR1C1	8495
ANKRD1	8556
FABP2	8748
CYP3A4	8758
FABP6	8946
STARD5	8990
PLA2G2F	8995
PON1	9209
PLA2G5	9231
MED11	9273
SLC10A2	9314
CYP11B2	9391
CYP2C9	9440
CYP2C19	9615
CYP4A22	9719
CYP8B1	9720

---

REACTOME_INNATE_IMMUNE_SYSTEM

REACTOME_INNATE_IMMUNE_SYSTEM

	227
set	REACTOME_INNATE_IMMUNE_SYSTEM
setSize	1002
pANOVA	1.76e-05
s.dist	-0.0801
p.adjustANOVA	0.00482

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SFTPA2	-12043
S100P	-12027
AZU1	-12019
FCGR3A	-11998
RNASE3	-11878
RAB44	-11827
FCGR3B	-11819
IFNB1	-11777
PTAFR	-11765
DGAT1	-11754
TYROBP	-11723
UBA7	-11683
CD300LB	-11675
FCER1G	-11663
LYZ	-11609
RNASE2	-11591
NBEAL2	-11526
CAMP	-11486
TREX1	-11463
POLR3E	-11461

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SFTPA2	-12043.0
S100P	-12027.0
AZU1	-12019.0
FCGR3A	-11998.0
RNASE3	-11878.0
RAB44	-11827.0
FCGR3B	-11819.0
IFNB1	-11777.0
PTAFR	-11765.0
DGAT1	-11754.0
TYROBP	-11723.0
UBA7	-11683.0
CD300LB	-11675.0
FCER1G	-11663.0
LYZ	-11609.0
RNASE2	-11591.0
NBEAL2	-11526.0
CAMP	-11486.0
TREX1	-11463.0
POLR3E	-11461.0
CLEC4A	-11454.0
DEFB126	-11440.0
CDC34	-11430.0
GNLY	-11422.0
TARM1	-11418.0
AGER	-11415.0
HP	-11347.0
DPP7	-11345.0
SURF4	-11331.0
HMOX1	-11301.0
C4BPA	-11284.0
DNAJC3	-11234.0
NOD2	-11218.0
AGPAT2	-11181.0
GUSB	-11178.0
SERPINB1	-11169.0
ADGRG3	-11161.0
S100A9	-11144.0
REG3A	-11138.0
SIGLEC14	-11128.0
TRPM2	-11109.0
ART1	-11070.0
CLEC4C	-11066.0
TIMP2	-11060.0
OSCAR	-11038.0
CYB5R3	-11017.0
ATP6V0D1	-11015.0
NCKIPSD	-11007.0
MAPK3	-10990.0
TRIM21	-10979.0
RHOA	-10972.0
ADAM8	-10957.0
CREG1	-10934.0
CTSZ	-10925.0
IFNA6	-10918.0
UNC93B1	-10899.0
UNC13D	-10890.0
ITGB2	-10882.0
MVP	-10840.0
GRN	-10837.0
AP1M1	-10791.0
CD63	-10781.0
FOLR3	-10780.0
HRAS	-10751.0
CTSG	-10716.0
PLD1	-10696.0
PGLYRP1	-10690.0
C4A	-10672.5
C4B	-10672.5
B4GALT1	-10659.0
CLEC7A	-10657.0
CTSD	-10656.0
RPS6KA1	-10646.0
SLPI	-10614.0
ATP6V0B	-10580.0
MS4A3	-10546.0
CANT1	-10524.0
PFKL	-10519.0
CXCR2	-10515.0
CLEC12A	-10513.0
DNM2	-10470.0
NFATC1	-10460.0
KCNAB2	-10450.0
CEACAM3	-10448.0
DEFB121	-10447.0
STK10	-10434.0
AP2A2	-10414.0
DEFB115	-10409.0
MGST1	-10399.0
MAVS	-10369.0
CD4	-10366.0
TRAF2	-10365.0
TRAF6	-10304.0
RETN	-10296.0
FCN3	-10284.0
ALAD	-10253.0
SLC15A4	-10250.0
SIGIRR	-10245.0
PDPK1	-10204.0
NCF2	-10203.0
DDX41	-10154.0
FCGR2A	-10113.0
MUC5B	-10096.0
ATP6V1C2	-10091.0
LTA4H	-10086.0
P2RX7	-10082.0
TOLLIP	-10076.0
ATP8B4	-10072.0
FUCA2	-10049.0
CYFIP1	-10047.0
DSN1	-10041.0
PSMD2	-10038.0
TICAM2	-10025.0
DOK3	-10015.0
QSOX1	-9988.0
CASP10	-9975.0
C3	-9967.0
MNDA	-9954.0
CD300A	-9936.0
CFHR2	-9931.0
PLPP5	-9907.0
FPR2	-9903.0
TNFAIP6	-9902.0
ARL8A	-9896.0
PRKACA	-9870.0
TRIM56	-9868.0
SYNGR1	-9858.0
VTN	-9848.0
PDAP1	-9833.0
MAPKAPK3	-9830.0
CARD9	-9824.0
LAMP1	-9778.0
PPIE	-9776.0
DNAJC5	-9767.0
CREBBP	-9764.0
F2	-9740.0
MMP25	-9738.0
SRC	-9726.0
TKFC	-9722.0
ATP6V0C	-9699.0
LEAP2	-9688.0
GLIPR1	-9684.0
OLR1	-9612.0
ARPC1B	-9607.0
TCIRG1	-9603.0
CHIT1	-9593.0
ACLY	-9570.0
SFTPD	-9508.0
RNF135	-9502.0
NCR2	-9463.0
ATP6V1B2	-9453.0
IMPDH1	-9440.0
FADD	-9413.0
ITPR3	-9355.0
NRAS	-9345.0
CARD11	-9331.0
RELA	-9312.0
DHX58	-9309.0
AMPD3	-9281.0
MS4A2	-9266.0
PRG3	-9265.0
LPCAT1	-9234.0
PDXK	-9201.0
PLD3	-9178.0
PYGB	-9165.0
MYO9B	-9163.0
GAA	-9160.0
CGAS	-9126.0
RPS6KA5	-9125.0
PRDX6	-9103.0
RIPK1	-9090.0
ACTR1B	-9089.0
NLRC5	-9067.0
CTSB	-9029.0
ALOX5	-9020.0
BST2	-8975.0
RAB4B	-8972.0
MEFV	-8959.0
CR1	-8956.0
ATP11A	-8950.0
PELI2	-8931.0
SEMG1	-8885.0
CAB39	-8881.0
FGB	-8843.0
TMEM30A	-8841.0
MUC3A	-8814.0
RELB	-8771.0
DEFA6	-8755.0
SERPINA1	-8752.0
IGF2R	-8732.0
NLRC3	-8696.0
NCSTN	-8683.0
PLA2G6	-8669.0
NCF4	-8612.0
MAPKAPK2	-8608.0
IFNA14	-8601.0
PTPRJ	-8552.0
MAP3K14	-8484.0
PIK3R1	-8469.0
CD59	-8454.0
LRRC14	-8422.0
SARM1	-8415.0
NCKAP1L	-8389.0
POLR2L	-8369.0
CPN2	-8365.0
ANPEP	-8360.0
C5AR1	-8334.0
C8A	-8292.0
CD14	-8233.0
ORM2	-8232.0
LTF	-8229.0
RHOG	-8185.0
ROCK1	-8181.0
RAB5C	-8174.0
PSMB7	-8167.0
CEACAM8	-8126.0
ATP6V0A2	-8120.0
LGMN	-8097.0
TIRAP	-8085.0
VAT1	-8057.0
VCP	-8043.0
TP53	-8010.0
TAB2	-7994.0
RAB27A	-7978.0
N4BP1	-7935.0
BAIAP2	-7933.0
PLAC8	-7912.0
KRAS	-7903.0
PRKCD	-7879.0
NAPRT	-7876.0
PSMD8	-7863.0
BRK1	-7841.0
ITPR1	-7839.0
GALNS	-7824.0
LILRB2	-7819.0
CRACR2A	-7810.0
DYNC1H1	-7804.0
UBA3	-7758.0
EPX	-7755.0
HBB	-7751.0
LY96	-7675.0
MAPK1	-7647.0
COMMD3	-7577.0
DEFB123	-7547.0
TCN1	-7546.0
PRG2	-7539.0
ATP6V1B1	-7474.0
SCAMP1	-7469.0
SERPINB6	-7444.0
IFI16	-7417.0
IRAK3	-7363.0
POLR1D	-7356.0
LYN	-7353.0
LPO	-7325.0
PAFAH1B2	-7323.0
BPIFA1	-7294.0
TXNDC5	-7289.0
LIMK1	-7288.0
TICAM1	-7278.0
ARPC1A	-7219.0
S100A11	-7211.0
CFB	-7210.0
KCMF1	-7182.0
CDC42	-7164.0
NFATC2	-7111.0
STK11IP	-7085.0
ITGAL	-7046.0
NLRC4	-7008.0
TLR1	-7006.0
ITGAX	-6960.0
TANK	-6950.0
CXCR1	-6925.0
TLR2	-6741.0
CCL17	-6735.0
NLRX1	-6733.0
CREB1	-6716.0
CLU	-6713.0
GYG1	-6710.0
RAP1B	-6680.0
DBNL	-6651.0
PRKDC	-6637.0
PSME4	-6624.0
IFNA1	-6605.0
WASL	-6596.0
TREM1	-6567.0
CAPN1	-6557.0
NHLRC3	-6542.0
VAV3	-6523.0
ATP6V1E2	-6518.0
RIPK3	-6517.0
MAP2K3	-6505.0
PTGES2	-6477.0
ARMC8	-6444.0
TBK1	-6415.0
S100A8	-6408.0
EEF2	-6398.0
JUP	-6376.0
AOC1	-6367.0
MAPK9	-6360.0
CD180	-6348.0
DEFB110	-6344.0
SLC27A2	-6309.0
IQGAP2	-6291.0
CASP2	-6289.0
CAND1	-6264.0
POLR3C	-6259.0
PIK3R2	-6257.0
CD300E	-6256.0
CD68	-6250.0
CALM1	-6248.0
SOS1	-6228.0
CD58	-6215.0
LGALS3	-6179.0
POLR3K	-6171.0
MAPK7	-6156.0
CTSL	-6148.0
RNASE7	-6142.0
C5	-6129.0
CPNE1	-6092.0
GLB1	-6067.0
HVCN1	-6058.0
CFD	-6051.0
FBXW11	-6050.0
ATG7	-6042.0
ELMO1	-6023.0
NEU1	-6004.0
WIPF2	-5943.0
ITPR2	-5932.0
RAB18	-5919.0
CUL1	-5886.0
MYO5A	-5866.0
CFHR5	-5857.0
ACTR2	-5826.0
CLEC4E	-5785.0
GCA	-5768.0
PAK2	-5763.0
CTSA	-5671.0
TXN	-5656.0
BPIFB6	-5644.0
SERPINB10	-5627.0
PPP2R1A	-5620.0
YES1	-5599.0
DDOST	-5593.0
TNFRSF1B	-5582.0
LAMTOR1	-5574.0
NCK1	-5559.0
AGL	-5511.0
RAC1	-5471.0
WIPF1	-5465.0
TEC	-5418.0
VAV2	-5410.0
MYO1C	-5402.0
ALDOA	-5349.0
MAPK11	-5323.0
NLRP3	-5298.0
PANX1	-5260.0
ELMO2	-5259.0
TRAF3	-5228.0
UBE2M	-5223.0
DUSP6	-5212.0
HTN3	-5210.0
SIGLEC15	-5171.0
PSMD13	-5161.0
ORMDL3	-5153.0
ABL1	-5137.0
SKP1	-5130.0
PLD2	-5090.0
SIGLEC9	-5087.0
MUCL1	-5086.0
BRI3	-5052.0
SNAP29	-5043.0
CPN1	-5029.0
IRAK4	-4973.0
PI3	-4967.0
HEBP2	-4914.0
TMBIM1	-4901.0
RAB14	-4878.0
STOM	-4867.0
C1orf35	-4848.0
SPTAN1	-4822.0
CXCL1	-4817.0
PLCG2	-4748.0
CD93	-4727.0
GSTP1	-4595.0
PTPN11	-4589.0
ADA2	-4554.0
C6orf120	-4533.0
CKAP4	-4522.0
PLAU	-4491.0
PSMB2	-4485.0
PSMD5	-4468.0
TIFA	-4453.0
STAT6	-4449.0
ABI2	-4422.0
POLR3A	-4409.0
PSMD4	-4377.0
USP14	-4362.0
RAB24	-4350.0
PELI3	-4327.0
PSMD1	-4322.0
PPP2CA	-4303.0
IQGAP1	-4277.0
LRRFIP1	-4258.0
GSN	-4251.0
C8G	-4240.0
CHUK	-4213.0
TRAPPC1	-4197.0
RAB5B	-4193.0
CTSV	-4172.0
CASP9	-4118.0
TNIP2	-4114.0
GSDMD	-4074.0
CD46	-4054.0
VAMP8	-4047.0
ADGRE3	-4041.0
ATP6V1H	-4034.0
DNM3	-4015.0
PSMC1	-4003.0
CAP1	-3968.0
MAP2K6	-3941.0
RASGRP2	-3932.0
SELL	-3929.0
C6	-3927.0
TLR5	-3894.0
PPP2R1B	-3877.0
ARPC3	-3860.0
CASP4	-3854.0
PLD4	-3831.0
CPB2	-3807.0
PSMF1	-3800.0
PSMB10	-3782.0
PRSS3	-3781.0
NF2	-3770.0
BPI	-3751.0
GM2A	-3713.0
PSMB9	-3711.0
EP300	-3709.0
CCR6	-3681.0
S100A7	-3643.0
DYNC1LI1	-3617.0
PPP3CA	-3593.0
PLPP4	-3582.0
TRIM25	-3581.0
PTX3	-3531.0
TRIM4	-3505.0
HMOX2	-3482.0
DOCK2	-3481.0
DIAPH1	-3476.0
RNF216	-3460.0
DEFB118	-3454.0
IST1	-3419.0
ATG5	-3406.0
POLR3G	-3378.0
DEFB134	-3317.0
PRKCE	-3273.0
PIK3CB	-3260.0
ATP6V1C1	-3254.0
ECSIT	-3198.0
DNM1	-3177.0
PLA2G2A	-3175.0
CAPZA2	-3154.0
DEFB1	-3136.0
CYFIP2	-3066.0
ITGAV	-3056.0
RAB10	-3046.0
IRAG2	-3035.0
ACAA1	-3023.0
CCR2	-3021.0
VRK3	-3014.0
SLC2A5	-2896.0
CRK	-2873.0
MPO	-2851.0
ARSB	-2835.0
ATP6V1A	-2825.0
TLR10	-2816.0
ARHGAP45	-2786.0
DUSP3	-2785.0
CAT	-2776.0
NKIRAS1	-2772.0
PIK3C3	-2764.0
POLR3D	-2756.0
PTPRN2	-2731.0
FGL2	-2725.0
CTNNB1	-2706.0
PIN1	-2693.0
MANBA	-2686.0
RPS6KA2	-2625.0
NPC2	-2608.0
ITGAM	-2602.0
JUN	-2590.0
WIPF3	-2581.0
IFNA2	-2571.0
PLEKHO2	-2565.0
ELANE	-2542.0
BCL2L1	-2540.0
AIM2	-2489.0
MAP2K4	-2474.0
MALT1	-2471.0
CTSS	-2453.0
CRCP	-2430.0
DTX4	-2429.0
ALDOC	-2424.0
ATP6V1G3	-2405.0
ATP6V0E2	-2391.0
PSMB11	-2381.0
RAF1	-2378.0
PTPN4	-2361.0
ADGRE5	-2346.0
KRT1	-2327.0
PSMA5	-2270.0
P2RX1	-2250.0
FAF2	-2238.0
UBR4	-2210.0
PROS1	-2193.0
MAP3K1	-2191.0
PRTN3	-2183.0
HEXB	-2179.0
PYCARD	-2170.0
ATF1	-2160.0
CMTM6	-2149.0
UBE2K	-2135.0
PTPN6	-2123.0
NOD1	-2098.0
ARPC2	-2036.0
RAB37	-2035.0
ATP6V1F	-2033.0
MRE11	-2030.0
ANXA2	-1995.0
NME2	-1941.0
CLEC10A	-1931.0
NFATC3	-1884.0
DOCK1	-1837.0
RAB7A	-1836.0
SLC11A1	-1795.0
ATP6V1E1	-1785.0
NLRP1	-1780.0
CRISPLD2	-1752.0
NFKB2	-1736.0
UBE2L6	-1730.0
CD81	-1724.0
PPP2R5D	-1699.0
STING1	-1684.0
TAB1	-1680.0
PPP3R1	-1672.0
FGR	-1652.0
PLAUR	-1650.0
ATP11B	-1613.0
CHI3L1	-1611.0
KPNB1	-1610.0
MAPK14	-1601.0
SIRPA	-1592.0
ISG15	-1555.0
CEACAM1	-1490.0
PGLYRP2	-1453.0
ATF2	-1383.0
WASF2	-1372.0
NFKBIB	-1367.0
IRAK2	-1366.0
FOS	-1359.0
SLC44A2	-1352.0
SEM1	-1346.0
NOS2	-1338.0
DNAJC13	-1325.0
NCKAP1	-1320.0
STBD1	-1269.0
DEFB104A	-1249.5
DEFB104B	-1249.5
POLR2F	-1243.0
CLEC4D	-1234.0
VCL	-1222.0
HSPA1B	-1221.0
HPSE	-1210.0
PSMD6	-1201.0
CCT2	-1182.0
CRISP3	-1162.0
TMEM63A	-1158.0
MUC16	-1152.0
TLR6	-1113.0
SAA1	-1095.0
PPP2CB	-1082.0
FCER1A	-1071.0
GAB2	-1066.0
C5AR2	-1045.0
DYNLT1	-1027.0
MAP2K1	-974.0
CD177	-937.0
RAB3A	-912.0
ATAD3B	-888.0
CD209	-874.0
ABCA13	-778.0
VNN1	-770.0
CLEC5A	-762.0
HSPA8	-751.0
ALDH3B1	-747.0
UBE2N	-700.0
WASF3	-686.0
HK3	-656.0
MUC17	-651.0
TLR4	-646.0
ZBP1	-640.0
C7	-632.0
PGM2	-621.0
PCBP2	-605.0
CYBA	-592.0
IKBKB	-552.0
CYSTM1	-546.0
PSMB6	-534.0
POLR2K	-528.0
FYN	-487.0
ABI1	-466.0
RAC2	-415.0
CD53	-413.0
PKM	-362.0
DEFB116	-344.0
PSMC4	-326.0
VAV1	-323.0
DERA	-315.0
RAB6A	-286.0
COLEC11	-272.0
ATOX1	-267.0
LILRA3	-261.0
MUC5AC	-258.0
APRT	-231.0
XRCC5	-187.0
ARSA	-175.0
PGM1	-160.0
KLRD1	-151.0
SIRPB1	-138.0
ACTR3	-130.0
TAX1BP1	-124.0
RAB31	-104.0
PSMA3	-63.0
GPI	-34.0
ANO6	-6.0
DYNLL1	26.0
PGAM1	27.0
HTN1	42.0
PSMA8	45.0
MEF2C	62.0
CRP	126.0
FABP5	133.0
VAPA	159.0
PSMA1	206.0
CPNE3	235.0
POLR2H	252.0
TMEM179B	285.0
NLRP4	325.0
PSMD9	385.0
C1R	389.0
IKBKE	423.0
ATP6V0A1	425.0
BPIFB1	476.0
PSMC3	511.0
CAPZA1	546.0
SRP14	550.0
HSP90AA1	563.0
PSME1	574.0
DEFB135	583.0
LAIR1	590.0
PPP3CB	607.0
BCL2	630.0
PIK3R4	631.0
A1BG	674.0
ACP3	698.0
ATP6V0A4	742.0
PSTPIP1	786.0
CST3	792.0
FUCA1	820.0
DHX36	829.0
ATP8A1	838.0
MYH9	883.0
APP	942.0
GGH	1039.0
ATP6V0E1	1057.0
ICAM3	1086.0
CEP290	1087.0
CPPED1	1126.0
KLRK1	1154.0
CFH	1248.0
PAK1	1260.0
CASP1	1269.0
RIGI	1281.0
APEH	1295.0
AAMP	1346.0
ORM1	1366.0
TUBB	1394.0
ALPK1	1415.0
MUC12	1420.0
WASF1	1436.0
CASP8	1467.0
SDCBP	1468.0
PSMD12	1473.0
SOCS1	1493.0
IRF7	1582.0
CHRNB4	1643.0
DUSP4	1644.0
UBE2D2	1756.0
UBE2D3	1842.0
CD19	1851.0
LRRC7	1862.0
CSNK2B	1887.0
MAN2B1	1897.0
PIK3CA	2017.0
UBE2D1	2022.0
TXNIP	2064.0
RAP1A	2073.0
COTL1	2089.0
PYGL	2090.0
APOB	2093.0
PSMD11	2103.0
RASGRP4	2165.0
ATP6V1D	2216.0
MAP2K7	2221.0
HSP90AB1	2253.0
PRCP	2258.0
LBP	2284.0
ASAH1	2304.0
YPEL5	2322.0
C4BPB	2334.0
VPS35L	2341.0
POLR3B	2342.0
GZMM	2422.0
AHCYL1	2482.0
CTSH	2500.0
BST1	2539.0
ENPP4	2549.0
ACTG1	2573.0
HCK	2605.0
HLA-A	2617.0
GMFG	2695.0
ARHGAP9	2729.0
EEF1A1	2745.0
HMGB1	2754.0
DUSP7	2757.0
PRKCQ	2767.0
DHX9	2781.0
MUC15	2814.0
TLR9	2856.0
HGSNAT	2884.0
QPCT	2907.0
COMMD9	2910.0
PSME3	2934.0
NOS3	2969.0
MLEC	3021.0
EEA1	3053.0
SERPING1	3064.0
MUC4	3092.0
NFKB1	3151.0
MUC6	3184.0
NFKBIA	3202.0
PIGR	3223.0
CSTB	3247.0
AHSG	3250.0
PGLYRP4	3253.0
TSPAN14	3285.0
PSMD14	3291.0
DEFB132	3384.0
DEFB125	3402.0
PSAP	3410.0
RAP2B	3413.0
TMC6	3469.0
PPIA	3479.0
RASGRP1	3527.0
ATP6V1G1	3534.0
PSMD3	3550.0
MAP3K8	3561.0
UBE2V1	3562.0
RHOF	3620.0
PSMC5	3651.0
FCAR	3707.0
PSMA2	3743.0
CHGA	3767.0
LAMTOR2	3777.0
IFNA16	3808.0
CD36	3843.0
IFIH1	3865.0
PELI1	3909.0
BIRC2	3936.0
APAF1	3974.0
XRCC6	4006.0
BCL10	4080.0
LRG1	4106.0
CDA	4129.0
BIRC3	4171.0
TNFAIP3	4187.0
ATG12	4221.0
PSMC6	4259.0
RNF125	4274.0
NFAM1	4278.0
RBSN	4336.0
RIPK2	4343.0
POLR3H	4348.0
PSMD7	4369.0
PSMB8	4390.0
IMPDH2	4456.0
ARG1	4473.0
IKBIP	4480.0
PSMA7	4493.0
MBL2	4498.0
RAB3D	4535.0
SUGT1	4549.0
PSMB4	4570.0
OSTF1	4627.0
FTL	4671.0
C1QC	4687.0
SERPINA3	4743.0
ERP44	4757.0
SYK	4767.0
TRIM32	4786.0
NOS1	4844.0
TOMM70	4850.0
GPR84	4929.0
SLC2A3	4940.0
ITCH	5007.0
PSMA6	5015.0
FLG2	5049.0
ARPC5	5098.0
LAT2	5115.0
CTSC	5130.0
ADAM10	5192.0
S100B	5197.0
CFHR4	5201.0
HERC5	5202.0
DEFA5	5219.5
ARPC4	5323.0
DEGS1	5324.0
MAPK13	5346.0
C3AR1	5455.0
CYLD	5465.0
GNS	5528.0
ILF2	5562.0
PSMB1	5600.0
IRF3	5604.0
MYO10	5616.0
GHDC	5627.0
SHC1	5628.0
IL1B	5632.0
CD247	5640.0
BTRC	5660.0
HSPA6	5708.0
CTSK	5761.0
TREM2	5764.0
MASP2	5813.0
MYH2	5841.0
NKIRAS2	5850.0
POLR1C	5872.0
TLR3	5877.0
PRKCSH	5888.0
NFASC	5911.0
CDK13	5930.0
TOM1	5937.0
BIN2	5969.0
BPIFA2	5988.0
DSP	6013.0
ACTB	6120.0
IFNA5	6169.0
RPS27A	6202.0
PA2G4	6219.0
CD55	6247.0
PTK2	6296.0
CCT8	6338.0
CR2	6343.0
MAPK8	6356.0
C2	6372.0
SLCO4C1	6399.0
MAP3K7	6414.0
PTPRB	6460.0
PRKACB	6462.0
PNP	6479.0
MUC21	6495.0
CD44	6533.0
FCN2	6576.0
NIT2	6615.0
MME	6617.0
MUC7	6633.0
HSP90B1	6662.0
B2M	6679.0
COPB1	6688.0
ACTR10	6689.0
PSEN1	6700.0
ICAM2	6725.0
AGA	6756.0
RNASET2	6772.0
LY86	6779.0
GOLGA7	6782.0
PSMA4	6896.0
GRB2	6943.0
SFTPA1	6966.0
DEFB133	6970.0
UBA52	7023.0
DEFB127	7034.0
REG3G	7107.0
FGG	7132.0
PPBP	7177.0
MEF2A	7210.0
NDUFC2	7216.0
MUC1	7245.0
CNN2	7257.0
TXK	7291.0
PSME2	7312.0
HLA-C	7317.0
TUBB4B	7335.0
SVIP	7336.0
SNAP25	7342.0
MAPK10	7349.0
HLA-E	7373.0
UBC	7391.0
DEFB113	7443.0
PRKACG	7445.0
POLR2E	7449.0
MAPK12	7473.0
CFI	7507.0
LCN2	7692.0
IDH1	7698.0
USP18	7790.0
MUC13	7805.0
RNASE8	7825.0
HLA-B	7828.0
EPPIN-WFDC6	7831.0
FTH1	7833.0
DEFB119	7845.0
LCP2	7873.0
TTR	7877.0
SNAP23	7885.0
S100A1	7936.0
PECAM1	7966.0
CNPY3	7991.0
LAT	8043.0
SIKE1	8063.0
MYD88	8066.0
PKP1	8071.0
PLCG1	8112.0
PSMB5	8115.0
CD47	8141.0
PSMC2	8147.0
C1S	8164.0
DEFB124	8186.0
UBB	8218.0
MIF	8239.0
FCN1	8247.0
PSMB3	8251.0
FRK	8262.0
CLEC6A	8292.0
PADI2	8309.0
GDI2	8312.0
MMP9	8323.0
FGA	8332.0
GSDME	8339.0
DEFB114	8343.0
ATP6V1G2	8380.0
FPR1	8456.0
LAMTOR3	8466.0
PTPRC	8483.0
COLEC10	8491.0
PGLYRP3	8492.0
RNASE6	8522.0
HSPA1A	8559.0
POLR3F	8563.0
DEFB136	8579.0
SIGLEC5	8670.0
EPPIN	8724.0
MASP1	8750.0
SERPINB12	8853.0
IFNA8	8871.0
HRNR	8877.0
ATP6V0D2	8885.0
MMP8	8935.0
MUC20	8947.0
ITK	8970.0
CFL1	8973.0
DCD	9022.0
BPIFB4	9049.0
C9	9092.0
IFNA21	9119.0
BPIFB2	9128.0
DEFB129	9146.0
MCEMP1	9148.0
C1QA	9149.0
DEFB128	9157.0
DSG1	9164.0
LILRB3	9171.0
CCL22	9179.0
S100A7A	9189.0
ITLN1	9271.0
SERPINB3	9302.0
C1QB	9306.0
LCK	9316.0
C8B	9331.0
MGAM	9347.0
POLR3GL	9373.0
DSC1	9388.0
OLFM4	9404.0
S100A12	9525.0
DEFA4	9539.0
CALML5	9573.0
GRAP2	9593.0
TBC1D10C	9599.0
IFNA13	9648.0
CD33	9673.0
CEACAM6	9736.0
CD3G	9855.0
IFNA7	9857.0

---

REACTOME_CHROMATIN_MODIFYING_ENZYMES

REACTOME_CHROMATIN_MODIFYING_ENZYMES

	558
set	REACTOME_CHROMATIN_MODIFYING_ENZYMES
setSize	252
pANOVA	4.12e-05
s.dist	-0.15
p.adjustANOVA	0.00966

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KMT2D	-11849
MTA1	-11612
H2BC26	-11565
DOT1L	-11442
SETD1A	-11236
PADI6	-11230
H3C12	-11204
WDR5	-11145
H2AC25	-11059
CARM1	-10948
BRD1	-10935
KAT8	-10869
PHF2	-10856
NCOR2	-10707
KDM4B	-10581
TADA2B	-10549
PRMT1	-10488
SETD6	-10364
COPRS	-10184
MBD3	-10056

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KMT2D	-11849.0
MTA1	-11612.0
H2BC26	-11565.0
DOT1L	-11442.0
SETD1A	-11236.0
PADI6	-11230.0
H3C12	-11204.0
WDR5	-11145.0
H2AC25	-11059.0
CARM1	-10948.0
BRD1	-10935.0
KAT8	-10869.0
PHF2	-10856.0
NCOR2	-10707.0
KDM4B	-10581.0
TADA2B	-10549.0
PRMT1	-10488.0
SETD6	-10364.0
COPRS	-10184.0
MBD3	-10056.0
KAT2B	-10050.0
H2AZ2	-9922.0
SMARCD1	-9904.0
ATXN7L3	-9843.0
CREBBP	-9764.0
TRRAP	-9712.0
SMARCA4	-9645.0
KANSL3	-9638.0
KDM3B	-9562.0
JADE1	-9482.0
ELP6	-9474.0
H3C8	-9465.0
H3C3	-9339.0
TAF5L	-9333.0
RELA	-9312.0
H2BC1	-9258.0
KMT5A	-9227.0
DMAP1	-9222.0
SUDS3	-9102.0
EP400	-9016.0
SUPT20H	-8970.0
H2BC13	-8955.0
H2AC1	-8908.0
PHF20	-8821.0
DNMT3A	-8756.0
JADE2	-8703.0
EHMT1	-8668.0
KMT2E	-8622.0
TADA1	-8600.0
CHD3	-8493.0
H2AC12	-8434.0
H2AC15	-8351.0
KAT6B	-8307.0
H2AC16	-8268.0
SETD3	-8184.0
ARID1A	-8158.0
NSD2	-7884.0
SMARCC2	-7750.0
KDM2A	-7686.0
HAT1	-7664.0
PADI1	-7598.0
MSL1	-7529.0
KANSL1	-7516.0
ELP3	-7378.0
H2AC21	-7252.0
ARID1B	-7237.0
H2BC15	-7227.0
ENY2	-7202.0
H2BC11	-7099.0
H2BC8	-7060.0
PRMT3	-6984.0
H2BC10	-6977.0
RCOR1	-6929.0
KDM4A	-6904.0
EHMT2	-6775.0
H2AC8	-6751.0
H2AC13	-6730.0
BRMS1	-6607.0
SMARCE1	-6519.0
PBRM1	-6498.0
ARID2	-6441.0
AEBP2	-6409.0
HDAC3	-6372.0
ING5	-6214.0
H2AZ1	-6211.0
H2BC21	-6060.0
H2AC6	-6049.0
KMT2C	-6024.0
H4C13	-5978.0
H3C11	-5690.0
EPC1	-5683.0
PADI3	-5652.0
JAK2	-5400.0
MORF4L1	-5381.0
GATAD2A	-5351.0
KAT6A	-5306.0
NSD3	-5202.0
KDM4D	-5126.0
ARID4B	-5114.0
CHD4	-4900.0
ELP4	-4798.0
H2AX	-4784.0
H3C10	-4692.0
TAF12	-4631.0
KDM2B	-4609.0
MCRS1	-4479.0
KDM5B	-4459.0
YEATS2	-4361.0
EZH2	-4305.0
SETD2	-4276.0
SMARCD2	-4160.0
SGF29	-4120.0
SMYD2	-4023.0
SETD1B	-3943.0
PHF21A	-3883.0
HDAC10	-3826.0
ACTL6B	-3773.0
SMYD3	-3768.0
ASH1L	-3740.0
EP300	-3709.0
SMARCC1	-3694.0
SAP18	-3665.0
DPY30	-3640.0
KMT5B	-3516.0
SUZ12	-3439.0
H2BC5	-3284.0
MSL2	-3253.0
H2BC12	-3226.0
KDM4C	-3155.0
SMARCA2	-3060.0
SAP30L	-3058.0
KMT5C	-2935.0
SETDB1	-2857.0
ARID5B	-2696.0
H2AC20	-2661.0
SETD7	-2655.0
H3C6	-2591.0
H3C1	-2553.0
PADI4	-2488.0
HDAC2	-2399.0
ING4	-2247.0
PRMT5	-2220.0
HDAC1	-2197.0
KAT2A	-2185.0
NCOA2	-2061.0
H2AJ	-2052.0
PRDM16	-2025.0
CDK4	-2008.0
ATXN7	-1970.0
MTA2	-1969.0
KAT5	-1924.0
EED	-1848.0
NFKB2	-1736.0
SUPT3H	-1644.0
H4C2	-1542.0
KDM1B	-1516.0
PAX3	-1434.0
KMT2B	-1414.0
PRMT7	-1393.0
ATF2	-1383.0
SUV39H2	-1310.0
H3C2	-1296.0
TBL1XR1	-1268.0
GPS2	-1263.0
KANSL2	-1174.0
KDM3A	-960.0
BRD8	-885.0
MTA3	-827.0
H2BC4	-667.0
MECOM	-664.0
KDM5A	-644.0
ING3	-589.0
SAP130	-162.0
REST	-139.0
RBBP4	-119.0
H4C8	118.0
BRPF1	121.0
ASH2L	345.0
BRPF3	346.0
MEAF6	512.0
ELP1	515.0
H4C3	548.0
ACTL6A	666.0
WDR77	730.0
RUVBL2	743.0
PRMT6	906.0
H2AC4	1158.0
CLOCK	1292.0
ARID4A	1389.0
KDM7A	1506.0
SMARCD3	1713.0
SUPT7L	1735.0
USP22	1819.0
ELP2	1826.0
NSD1	1832.0
H2AC7	1901.5
H2BC7	1901.5
ZZZ3	2000.0
RIOX2	2051.0
TAF9	2113.0
NCOR1	2130.0
RUVBL1	2146.0
DR1	2189.0
MBIP	2283.0
GATAD2B	2373.0
ELP5	2496.0
H3C4	2601.0
NCOA1	2647.0
MRGBP	3094.0
H2AC11	3095.0
NFKB1	3151.0
JMJD6	3463.0
TAF6L	3690.0
KDM1A	3744.0
RPS2	3798.0
H2BC3	3960.0
BRWD1	4044.0
KDM6B	4284.0
TADA2A	4329.0
H4C5	4340.0
HMG20B	4461.0
CCND1	4512.0
TADA3	4764.0
KAT7	4787.0
RBBP5	4947.0
VPS72	5691.0
ACTB	6120.0
SMARCB1	6293.0
KMT2A	6412.0
PRDM9	6560.0
H2BC17	6788.0
ATF7IP	7138.0
H2BC6	7354.0
H4C1	7519.0
H4C11	7668.0
H4C6	7701.0
H2AC17	7742.0
SETDB2	7802.0
YEATS4	7823.0
H4C16	7938.0
H4C4	8046.0
PADI2	8309.0
H2BC9	8440.5
H3C7	8440.5
H2BC14	8529.0
H4C9	8578.0
TAF10	8637.0
H4C12	8975.0
SAP30	9057.0
H2AC14	9533.0
H2AC18	9604.5
H2AC19	9604.5

---

REACTOME_ASPIRIN_ADME

REACTOME_ASPIRIN_ADME

	1595
set	REACTOME_ASPIRIN_ADME
setSize	42
pANOVA	8.22e-05
s.dist	0.351
p.adjustANOVA	0.0169

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2C19	9615
ACSM4	9534
CYP2C9	9440
ACSM2A	9029
CYP3A4	8758
CYP2C8	8325
UGT2B7	7929
GLYATL3	7263
GLYAT	7053
UGT2B4	6754
UGT2B11	6737
GLYATL1	6659
UGT1A3	6311
BCHE	5967
UGT1A8	5490
UGT1A7	5370
UGT1A9	5210
UGT2B15	5178
ABCC2	5010
UGT1A4	4750

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2C19	9615
ACSM4	9534
CYP2C9	9440
ACSM2A	9029
CYP3A4	8758
CYP2C8	8325
UGT2B7	7929
GLYATL3	7263
GLYAT	7053
UGT2B4	6754
UGT2B11	6737
GLYATL1	6659
UGT1A3	6311
BCHE	5967
UGT1A8	5490
UGT1A7	5370
UGT1A9	5210
UGT2B15	5178
ABCC2	5010
UGT1A4	4750
ALB	4370
UGT1A6	4015
UGT2A1	3483
UGT3A1	3215
UGT1A5	2913
UGT2A2	2619
CES2	2397
SLC22A7	2226
UGT1A1	2139
ACSM5	1529
CYP2E1	676
UGT3A2	-275
CES1	-660
SLCO2B1	-3865
CYP2D6	-4218
BSG	-4269
UGT2A3	-4607
SLC16A1	-4820
ABCC3	-5165
GLYATL2	-8693
UGT2B17	-8880
ACSM2B	-10230

---

REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES

	394
set	REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES
setSize	30
pANOVA	0.000125
s.dist	0.405
p.adjustANOVA	0.0227

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
GRAP2	9593
LCK	9316
ITK	8970
HLA-DRA	8538
PLCG1	8112
LAT	8043
LCP2	7873
ENAH	7000
HLA-DPB1	6475
CD247	5640
CD101	4962
EVL	4855
HLA-DQA1	4376
HLA-DRB5	3407
ZAP70	3178
HLA-DQA2	2476
VASP	1418

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
GRAP2	9593
LCK	9316
ITK	8970
HLA-DRA	8538
PLCG1	8112
LAT	8043
LCP2	7873
ENAH	7000
HLA-DPB1	6475
CD247	5640
CD101	4962
EVL	4855
HLA-DQA1	4376
HLA-DRB5	3407
ZAP70	3178
HLA-DQA2	2476
VASP	1418
PAK1	1260
FYB1	684
HLA-DRB1	520
HLA-DQB2	507
HLA-DQB1	-3560
PLCG2	-4748
NCK1	-5559
PAK2	-5763
HLA-DPA1	-7387
CD4	-10366

---

REACTOME_RHOC_GTPASE_CYCLE

REACTOME_RHOC_GTPASE_CYCLE

	1370
set	REACTOME_RHOC_GTPASE_CYCLE
setSize	71
pANOVA	0.00036
s.dist	-0.245
p.adjustANOVA	0.0576

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF5	-11880
PREX1	-11127
PKN3	-10997
RHOA	-10972
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
PKN1	-9980
STX5	-9876
MCAM	-9835
ANLN	-9294
MYO9B	-9163
PIK3R1	-8469
MACO1	-8426
SLK	-8352
ROCK1	-8181
IQGAP3	-7949
ARHGAP18	-7762
ABR	-7628
VANGL1	-7498

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF5	-11880
PREX1	-11127
PKN3	-10997
RHOA	-10972
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
PKN1	-9980
STX5	-9876
MCAM	-9835
ANLN	-9294
MYO9B	-9163
PIK3R1	-8469
MACO1	-8426
SLK	-8352
ROCK1	-8181
IQGAP3	-7949
ARHGAP18	-7762
ABR	-7628
VANGL1	-7498
ARHGAP26	-7366
TFRC	-7152
ARHGAP1	-7025
BCR	-6531
FLOT2	-6527
JUP	-6376
CIT	-5523
VAV2	-5410
ARHGEF10	-5092
LMAN1	-5039
ARHGEF17	-4965
STOM	-4867
AKAP13	-4682
VAPB	-4633
ARHGAP21	-4511
ACBD5	-4475
FLOT1	-4439
ARHGEF1	-4410
IQGAP1	-4277
DAAM1	-3726
DIAPH1	-3476
ARHGAP39	-2999
LBR	-2962
ARHGEF40	-2699
ERBIN	-2546
ROCK2	-2459
VAMP3	-2222
FMNL2	-2212
TJP2	-2027
MCF2L	-1866
PKN2	-1812
TMPO	-1808
FMNL3	-1625
RTKN	-903
ARHGAP35	-669
ARHGDIA	-335
STARD13	344
ARHGEF28	410
DEPDC1B	418
ABCD3	1002
DIAPH3	2307
ARHGEF11	3152
DLC1	3276
ARHGEF12	3332
ARHGEF10L	4077
C1QBP	4992
ARHGEF25	5241
ARHGAP5	5904
RHOC	6854
ARHGAP32	7862
CAV1	8260

---

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

	1585
set	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3
setSize	679
pANOVA	0.00039
s.dist	-0.0798
p.adjustANOVA	0.0576

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	-12026
ARHGEF5	-11880
PLEKHG4	-11600
ROPN1	-11594
H2BC26	-11565
DVL3	-11552
H3C12	-11204
INCENP	-11201
S100A9	-11144
PREX1	-11127
LIMK2	-11100
YWHAB	-11084
NCKIPSD	-11007
PKN3	-10997
MAPK3	-10990
RHOA	-10972
DOCK6	-10904
TPM4	-10880
PARD6B	-10848
PLD1	-10696

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	-12026.0
ARHGEF5	-11880.0
PLEKHG4	-11600.0
ROPN1	-11594.0
H2BC26	-11565.0
DVL3	-11552.0
H3C12	-11204.0
INCENP	-11201.0
S100A9	-11144.0
PREX1	-11127.0
LIMK2	-11100.0
YWHAB	-11084.0
NCKIPSD	-11007.0
PKN3	-10997.0
MAPK3	-10990.0
RHOA	-10972.0
DOCK6	-10904.0
TPM4	-10880.0
PARD6B	-10848.0
PLD1	-10696.0
CAVIN1	-10678.0
VANGL2	-10613.0
HGS	-10582.0
RACGAP1	-10526.0
SRGAP2	-10441.0
STK10	-10434.0
KIF2B	-10339.0
EFHD2	-10225.0
PDPK1	-10204.0
NCF2	-10203.0
ARHGEF18	-10202.0
PRC1	-10185.0
SLC1A5	-10165.0
STK38	-10155.0
GFOD1	-10098.0
CYFIP1	-10047.0
DSN1	-10041.0
DYNC1LI2	-10030.0
CENPA	-10026.0
KIF5A	-10003.0
PKN1	-9980.0
CUL3	-9965.0
H2AZ2	-9922.0
GIT1	-9920.0
PGRMC2	-9912.0
PARD6A	-9890.5
TRAK1	-9887.0
STX5	-9876.0
MCAM	-9835.0
TUBA3C	-9788.0
PLEKHG6	-9771.0
ARHGEF2	-9756.0
ACTC1	-9754.0
TRA2B	-9745.0
TUBB1	-9731.0
SRC	-9726.0
KCTD13	-9663.0
ARPC1B	-9607.0
NDUFS3	-9549.0
H3C8	-9465.0
H3C3	-9339.0
RCC2	-9316.0
DYNLL2	-9313.0
DVL1	-9299.0
ANLN	-9294.0
SLITRK3	-9275.0
ANKLE2	-9272.0
H2BC1	-9258.0
TUBA1C	-9236.0
ARAP1	-9230.0
MYO9B	-9163.0
MAD1L1	-9158.0
ITGB1	-9073.0
ESYT1	-9061.0
STEAP3	-9042.0
CLASP1	-9015.0
ECT2	-9008.0
TUBA3E	-8966.0
ARHGAP17	-8957.0
H2BC13	-8955.0
RPS27	-8947.0
RND2	-8865.0
FARP2	-8827.0
YWHAQ	-8800.0
GPS1	-8747.0
WDR81	-8721.0
RANGAP1	-8701.0
CKB	-8697.0
NCF4	-8612.0
GMIP	-8602.0
PIK3R1	-8469.0
ARFGAP2	-8462.0
PAK4	-8450.0
MACO1	-8426.0
NCKAP1L	-8389.0
SLK	-8352.0
CPNE8	-8237.0
RAC3	-8230.0
FAM169A	-8201.0
ARHGAP33	-8188.0
RHOG	-8185.0
ROCK1	-8181.0
SPEN	-8099.0
PLEKHG2	-8089.0
VCP	-8043.0
IQGAP3	-7949.0
BAIAP2	-7933.0
STAM2	-7929.0
PRKCD	-7879.0
YWHAE	-7851.0
BRK1	-7841.0
FERMT2	-7831.0
DYNC1H1	-7804.0
WWP2	-7765.0
ARHGAP18	-7762.0
PRKCZ	-7754.0
NUP37	-7738.0
DDRGK1	-7736.0
ARHGAP29	-7729.0
ARHGEF19	-7725.0
ARHGAP11B	-7698.0
MAPK1	-7647.0
DDX39B	-7629.0
ABR	-7628.0
FNBP1	-7625.0
MYH14	-7587.0
MTR	-7507.0
VANGL1	-7498.0
RND3	-7436.0
RHPN2	-7410.0
MSI2	-7392.0
ARHGAP26	-7366.0
NUDC	-7335.0
BIRC5	-7316.0
LIMK1	-7288.0
PPP1CC	-7284.0
CENPP	-7256.0
H2BC15	-7227.0
TAOK3	-7221.0
ARPC1A	-7219.0
KLC1	-7189.0
SLITRK5	-7175.0
CDC42	-7164.0
TFRC	-7152.0
PHIP	-7103.0
H2BC11	-7099.0
NISCH	-7083.0
H2BC8	-7060.0
ARHGAP1	-7025.0
GOLGA3	-7023.0
LRRC1	-7017.0
ARHGAP23	-7015.0
H2BC10	-6977.0
CENPF	-6797.0
MYH11	-6762.0
NUP85	-6754.0
H2AC8	-6751.0
CENPQ	-6658.0
CLASP2	-6653.0
PLXND1	-6625.0
WASL	-6596.0
ARFGAP3	-6592.0
TRIP10	-6543.0
BCR	-6531.0
FLOT2	-6527.0
VAV3	-6523.0
KLC4	-6508.0
S100A8	-6408.0
JUP	-6376.0
RHPN1	-6364.0
ZNF512B	-6357.0
IQGAP2	-6291.0
LRRC41	-6274.0
SRRM1	-6266.0
PIK3R2	-6257.0
CPSF7	-6255.0
CALM1	-6248.0
SOS1	-6228.0
H2AZ1	-6211.0
AAAS	-6185.0
ANKFY1	-6176.0
DOCK3	-6155.0
KLC2	-6153.0
TEX2	-6145.0
RALBP1	-6130.0
TMEM87A	-6124.0
WDR91	-6091.0
CDC42EP2	-6084.0
PPP2R5E	-6080.0
FGD3	-6068.0
H2BC21	-6060.0
H2AC6	-6049.0
NUF2	-5988.0
H4C13	-5978.0
WIPF2	-5943.0
SHKBP1	-5917.0
KIF2C	-5909.0
DOCK8	-5851.0
ACTR2	-5826.0
PAK2	-5763.0
H3C11	-5690.0
FRS3	-5633.0
PPP2R1A	-5620.0
BLTP3B	-5587.0
LAMTOR1	-5574.0
NET1	-5573.0
NCK1	-5559.0
CIT	-5523.0
RHOBTB3	-5520.0
PKP4	-5476.0
RAC1	-5471.0
WIPF1	-5465.0
VAV2	-5410.0
NDEL1	-5396.0
PLXNA1	-5378.0
KLK2	-5364.0
MRTFA	-5354.0
MAPK11	-5323.0
MYL9	-5269.0
ELMO2	-5259.0
DLG5	-5220.0
KIF2A	-5206.0
ABL1	-5137.0
ARHGEF7	-5104.0
ARHGEF10	-5092.0
PLD2	-5090.0
GNA13	-5076.0
SPDL1	-5046.0
LMAN1	-5039.0
SYDE1	-4999.0
MIS12	-4990.0
ARHGEF17	-4965.0
MAP3K11	-4957.0
EMC3	-4898.0
STOM	-4867.0
SPTAN1	-4822.0
H2AX	-4784.0
TRAK2	-4779.0
SRF	-4762.0
H3C10	-4692.0
ZWINT	-4685.0
AKAP13	-4682.0
VAPB	-4633.0
ARAP3	-4556.0
CKAP4	-4522.0
ARHGAP21	-4511.0
DOCK5	-4496.0
ACBD5	-4475.0
FLOT1	-4439.0
ABI2	-4422.0
ARHGEF1	-4410.0
RHOT2	-4393.0
SFN	-4372.0
NOXA1	-4354.0
PPP2CA	-4303.0
EPHA2	-4298.0
IQGAP1	-4277.0
WHAMM	-4268.0
SGO2	-4256.0
GIT2	-4248.0
NDE1	-4186.0
ARHGEF26	-4184.0
CKAP5	-4180.0
MYO9A	-4177.0
CENPN	-4141.0
ARHGAP28	-4121.0
HTR7	-4046.0
MEN1	-3969.0
BASP1	-3948.0
PPP2R1B	-3877.0
ARPC3	-3860.0
CCDC88A	-3840.0
NF2	-3770.0
DAAM1	-3726.0
BAIAP2L2	-3719.0
JAG1	-3708.0
PPP1R12B	-3690.0
TUBB2A	-3682.0
SCRIB	-3674.0
MFN2	-3647.0
SWAP70	-3638.0
DYNC1LI1	-3617.0
CCNE1	-3606.0
FAM135A	-3529.0
HMOX2	-3482.0
DOCK2	-3481.0
DIAPH1	-3476.0
DNMBP	-3394.0
VRK2	-3354.0
FAM91A1	-3322.0
CPD	-3312.0
H2BC5	-3284.0
FGD4	-3233.0
H2BC12	-3226.0
ARHGAP27	-3204.0
KDM4C	-3155.0
COPS4	-3148.0
YWHAG	-3140.0
RNF20	-3138.0
CYFIP2	-3066.0
LEMD3	-3030.0
HSPE1	-3019.0
SRGAP1	-3018.0
PRAG1	-3013.0
ARHGAP39	-2999.0
LBR	-2962.0
PTK2B	-2883.0
PLIN3	-2830.0
SOWAHC	-2812.0
ARHGAP45	-2786.0
PIK3C3	-2764.0
HNRNPC	-2737.0
YWHAH	-2710.0
CTNNB1	-2706.0
ARHGEF40	-2699.0
PIN1	-2693.0
PTPN13	-2670.0
H2AC20	-2661.0
H3C6	-2591.0
WIPF3	-2581.0
H3C1	-2553.0
ERBIN	-2546.0
MYL12B	-2538.0
LETM1	-2527.0
PLEKHG3	-2525.0
SGO1	-2511.0
ROCK2	-2459.0
PFN2	-2427.0
ITGB3BP	-2415.0
GOPC	-2392.0
CDC42BPB	-2386.0
CCT7	-2338.0
RHOU	-2309.0
CENPT	-2308.0
TUBA1A	-2281.0
KNL1	-2274.0
TMEM59	-2265.0
TNFAIP1	-2260.0
CENPU	-2249.0
FAF2	-2238.0
VAMP3	-2222.0
FMNL2	-2212.0
ARHGAP24	-2119.0
ITSN1	-2089.0
NCOA2	-2061.0
H2AJ	-2052.0
ARPC2	-2036.0
TJP2	-2027.0
ARHGAP10	-1992.0
ITSN2	-1986.0
NSL1	-1968.0
OBSCN	-1917.0
SKA2	-1869.0
MCF2L	-1866.0
DOCK1	-1837.0
RAB7A	-1836.0
PPP1R12A	-1831.0
PRKCA	-1822.0
PKN2	-1812.0
CLIP1	-1810.0
TMPO	-1808.0
SAMM50	-1778.0
SKA1	-1739.0
ARAP2	-1708.0
PPP2R5D	-1699.0
NUP133	-1674.0
TUBAL3	-1663.0
FMNL3	-1625.0
SPTBN1	-1621.0
MAPK14	-1601.0
STAM	-1561.0
H4C2	-1542.0
KIDINS220	-1536.0
RHOV	-1528.0
CDC37	-1510.0
PRKCB	-1454.0
NUP98	-1397.0
FARP1	-1384.0
WASF2	-1372.0
PLXNB1	-1330.0
NCKAP1	-1320.0
NSFL1C	-1297.0
H3C2	-1296.0
STBD1	-1269.0
NCK2	-1242.0
CDH1	-1241.0
ARHGAP20	-1200.0
CCT2	-1182.0
FAM13B	-1135.0
DBT	-1133.0
PPP2CB	-1082.0
CDC25C	-1055.0
H3-3A	-1015.0
RTKN	-903.0
CDCA8	-902.0
OSBPL11	-900.0
UACA	-875.0
DOCK7	-750.0
SLC4A7	-709.0
TUBA4B	-707.0
WASF3	-686.0
SOS2	-671.0
ARHGAP35	-669.0
H2BC4	-667.0
CENPH	-647.0
RRAS2	-618.0
UBXN11	-617.0
CHN2	-604.0
CYBA	-592.0
ARHGAP12	-563.0
MPP7	-547.0
RAPGEF1	-467.0
ABI1	-466.0
TAGAP	-420.0
RAC2	-415.0
DYNC1I2	-374.0
CENPS	-358.0
ARHGDIA	-335.0
VAV1	-323.0
SH3RF1	-303.0
WDR11	-220.0
PDE5A	-196.0
YWHAZ	-146.0
ACTR3	-130.0
ALS2	-102.0
CCDC115	-87.0
XPO1	-11.0
NIPSNAP2	5.0
DYNLL1	26.0
PMF1	76.0
KIF14	97.0
H4C8	118.0
ARHGAP25	124.0
PLEKHG4B	131.0
TWF1	157.0
KIF5B	190.0
CTNNA1	230.0
ARHGEF3	242.0
CDC42SE2	267.0
FAM13A	276.0
STARD13	344.0
ALDH3A2	347.0
TUBB6	387.0
FGD2	390.0
CDKN1B	405.0
ARHGEF28	410.0
DEPDC1B	418.0
SHMT2	436.0
CDC42EP3	463.0
SYDE2	483.0
PCDH7	517.0
CLTC	529.0
H4C3	548.0
B9D2	554.0
HSP90AA1	563.0
ARHGAP40	599.0
PIK3R4	631.0
EPSTI1	641.0
DOCK9	702.0
ARHGAP22	731.0
ABL2	736.0
ZW10	752.0
DOCK10	761.0
MYH9	883.0
AKAP12	919.0
PREX2	931.0
RHOBTB1	961.0
H3-3B	1000.0
ABCD3	1002.0
TUBA4A	1016.0
ARHGAP15	1019.0
ARHGEF4	1055.0
H2AC4	1158.0
NGEF	1185.0
PPP1CB	1227.0
SEH1L	1257.0
PAK1	1260.0
TUBA1B	1291.0
CDC42BPA	1300.0
MYH10	1309.0
PEAK1	1325.0
CENPO	1350.0
WASF1	1436.0
FRS2	1458.0
PICALM	1483.0
FMNL1	1516.0
MAPRE1	1549.0
ANKRD26	1558.0
TUBA8	1565.0
PLEKHG5	1630.0
RALGAPA1	1663.0
VHL	1667.0
SH3BP1	1749.0
TUBB8	1769.0
TRIO	1806.0
ZWILCH	1868.0
PPP2R5C	1870.0
H2AC7	1901.5
H2BC7	1901.5
TPM3	1972.0
PIK3CA	2017.0
KNTC1	2034.0
PAK5	2054.0
DLG4	2057.0
GARRE1	2083.0
ARHGDIG	2094.0
RASGRF2	2104.0
NDUFA5	2149.0
NDC80	2184.0
HINT2	2235.0
HSP90AB1	2253.0
RHOBTB2	2273.0
VIM	2293.0
DIAPH3	2307.0
SCAI	2309.0
LMNB1	2321.0
CEP97	2328.0
RANBP2	2395.0
BAIAP2L1	2411.0
ARHGAP11A	2521.0
KIF18A	2526.0
PPP1R14A	2561.0
PAFAH1B1	2571.0
ACTG1	2573.0
ARHGAP44	2594.0
H3C4	2601.0
CTTN	2608.0
LIN7B	2616.0
RAP1GDS1	2717.0
ARHGAP9	2729.0
MAD2L1	2747.0
MYO6	2826.0
FAM83B	2876.0
TUBB4A	2909.0
RHOB	2970.0
ARHGAP31	2987.0
RHOQ	3006.0
CENPM	3009.0
ACTN1	3023.0
CDC20	3030.0
GJA1	3042.0
CENPL	3096.0
CDC42EP4	3116.0
TUBB3	3143.0
ARHGEF11	3152.0
ZAP70	3178.0
PPP2R5B	3187.0
PLK1	3211.0
PFN1	3225.0
DLC1	3276.0
MYO19	3300.0
ARHGEF12	3332.0
CSK	3354.0
MYL6	3386.0
CCT6A	3430.0
ARHGEF16	3461.0
PPP2R5A	3466.0
DOCK4	3500.0
FGD5	3516.0
MFN1	3576.0
RHOF	3620.0
ADD3	3669.0
AHCTF1	3696.0
DEF6	3729.0
KDM1A	3744.0
PLEKHG1	3789.0
MYLK	3793.0
TMOD3	3820.0
H2BC3	3960.0
DVL2	3968.0
WDR6	3977.0
CENPK	4004.0
TIAM2	4047.0
STMN2	4063.0
CAPZB	4075.0
ARHGEF10L	4077.0
SCFD1	4119.0
DSG2	4141.0
SPATA13	4148.0
KLC3	4184.0
RASAL2	4218.0
CCP110	4250.0
GRB7	4264.0
PIK3R3	4324.0
H4C5	4340.0
TXNL1	4366.0
DYNC1I1	4409.0
RHOJ	4455.0
POTEE	4476.0
KALRN	4576.0
MTX1	4706.0
TIAM1	4715.0
SH3PXD2A	4740.0
EVL	4855.0
STIP1	4898.0
BUB1B	4981.0
RBBP6	4987.0
C1QBP	4992.0
DBN1	4995.0
ARPC5	5098.0
KTN1	5170.0
RND1	5189.0
PAK6	5228.0
ARHGEF25	5241.0
DDX4	5264.0
RHOT1	5281.0
ARL13B	5290.0
KLK3	5302.0
ARPC4	5323.0
NUP160	5375.0
TAX1BP3	5434.0
SEC13	5529.0
KCTD3	5543.0
SRGAP3	5800.0
ARHGAP5	5904.0
TAOK1	5952.0
DST	5982.0
CENPC	5998.0
DSP	6013.0
CHN1	6091.0
ACTB	6120.0
SENP1	6187.0
TOR1AIP1	6206.0
PTK2	6296.0
BUB1	6603.0
RHOD	6750.0
H2BC17	6788.0
RHOC	6854.0
NUP43	6907.0
GRB2	6943.0
TUBB2B	6990.0
FILIP1	7083.0
ARHGAP8	7109.0
AMIGO2	7179.0
ARHGAP19	7278.0
ARHGEF39	7279.0
TUBB4B	7335.0
H2BC6	7354.0
CENPE	7359.0
NOXO1	7385.0
ARHGDIB	7447.0
H4C1	7519.0
COPS2	7523.0
ARHGAP42	7588.0
H4C11	7668.0
BUB3	7688.0
H4C6	7701.0
NUP107	7722.0
AURKB	7777.0
MUC13	7805.0
SEMA4F	7830.0
ARHGAP30	7842.0
SPC24	7861.0
ARHGAP32	7862.0
CFTR	7876.0
SNAP23	7885.0
FNBP1L	7920.0
H4C16	7938.0
ARHGEF15	7949.0
CDC42EP1	8007.0
H4C4	8046.0
RHOH	8152.0
CAV1	8260.0
IL32	8314.0
SPC25	8422.0
H2BC9	8440.5
H3C7	8440.5
H2BC14	8529.0
H4C9	8578.0
NOX3	8735.0
CDC42EP5	8763.0
YKT6	8795.0
CFL1	8973.0
H4C12	8975.0
DSG1	9164.0
LCK	9316.0
H2AC14	9533.0
H2AC18	9604.5
H2AC19	9604.5

---

REACTOME_PHOSPHOLIPID_METABOLISM

REACTOME_PHOSPHOLIPID_METABOLISM

	136
set	REACTOME_PHOSPHOLIPID_METABOLISM
setSize	201
pANOVA	0.000439
s.dist	-0.144
p.adjustANOVA	0.0576

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GDPD3	-11964
PLA2G4B	-11895
DGAT1	-11754
PISD	-11623
PNPLA2	-11444
ARF1	-11363
GPD1	-11352
AGPAT3	-11261
MFSD2A	-11240
AGPAT2	-11181
INPP5D	-10722
INPP5E	-10700
PLD1	-10696
CHKB	-10634
SYNJ2	-10589
PGS1	-10563
SBF1	-10143
OSBPL5	-9875
PTPMT1	-9661
PLA2G2D	-9631

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GDPD3	-11964
PLA2G4B	-11895
DGAT1	-11754
PISD	-11623
PNPLA2	-11444
ARF1	-11363
GPD1	-11352
AGPAT3	-11261
MFSD2A	-11240
AGPAT2	-11181
INPP5D	-10722
INPP5E	-10700
PLD1	-10696
CHKB	-10634
SYNJ2	-10589
PGS1	-10563
SBF1	-10143
OSBPL5	-9875
PTPMT1	-9661
PLA2G2D	-9631
VAC14	-9611
CSNK2A2	-9451
PNPLA7	-9322
GDE1	-9271
LPCAT1	-9234
PLEKHA2	-9223
PLA2G15	-9206
PLD3	-9178
PCYT2	-8923
INPP4B	-8826
PLD6	-8699
CHKA	-8672
PLA2G6	-8669
INPPL1	-8610
ARF3	-8585
PIK3R1	-8469
MTMR3	-8423
MTMR12	-8402
STARD10	-8283
PLAAT5	-8168
PIP5K1C	-8119
TNFAIP8L1	-8060
TPTE	-7969
MBOAT2	-7726
PLA2G12A	-7517
GDPD5	-7508
LIPH	-7423
DGAT2	-7371
INPP5K	-7218
ETNK2	-7080
PIP4K2B	-7031
PTDSS1	-7021
LPCAT3	-6901
PITPNB	-6726
PIK3R5	-6616
FIG4	-6400
PIK3R2	-6257
ACHE	-6174
CHPT1	-6121
CPNE1	-6092
TMEM86B	-6076
PI4K2A	-5982
RAB4A	-5793
PITPNM2	-5762
HADHB	-5692
PNPLA8	-5622
PLEKHA6	-5540
LPCAT2	-5445
LPCAT4	-5372
CSNK2A1	-5317
TNFAIP8L2	-5251
PI4KA	-5250
INPP4A	-5219
PNPLA6	-5164
GPAT4	-5113
PLD2	-5090
PI4KB	-5010
PITPNM1	-4971
PLB1	-4929
SACM1L	-4926
GPD2	-4908
RAB14	-4878
CHAT	-4854
DDHD2	-4592
PLA2G4F	-4523
PTDSS2	-4341
LPIN1	-4232
MBOAT1	-3974
PIK3R6	-3963
OSBPL8	-3920
MIGA2	-3870
PLD4	-3831
LPIN2	-3566
LPIN3	-3530
GPD1L	-3477
PLEKHA8	-3458
MTMR7	-3332
PIK3C2B	-3287
INPP5F	-3285
PIK3CB	-3260
PLA2G2A	-3175
PLA2G2E	-3128
PLA2G4D	-3038
AGPAT4	-3008
ABHD3	-2981
CDS2	-2932
ABHD4	-2925
PLA2G1B	-2921
PLEKHA5	-2910
GNPAT	-2841
CRLS1	-2811
PIK3C3	-2764
PTPN13	-2670
PIK3CG	-2606
SLC44A4	-2512
PLBD1	-2245
AGPAT5	-2235
HADHA	-1978
GPAT2	-1873
PLEKHA1	-1871
PI4K2B	-1772
PLA2R1	-1747
PEMT	-1427
STARD7	-1377
SLC44A2	-1352
PLAAT1	-1121
CEPT1	-1118
MTMR4	-776
PLA1A	-633
MTMR9	-611
ALPI	-545
SBF2	-536
LCLAT1	-496
MGLL	-292
SYNJ1	-178
PLA2G4C	-80
PLEKHA4	154
DDHD1	217
CPNE3	235
ETNK1	257
MTMR14	298
PCYT1A	331
PIP5K1A	335
PIP4P1	461
PLEKHA3	479
PIK3R4	631
ETNPPL	721
RUFY1	727
ACP6	1266
PIP4K2A	1306
PIP5K1B	1695
PLAAT3	1820
CSNK2B	1887
CPNE6	1915
AGPAT1	2004
PIK3CA	2017
MBOAT7	2137
PLA2G4A	2243
PTEN	2245
CDS1	2320
GPCPD1	2338
PIK3C2A	2634
LPGAT1	2703
CDIPT	2722
MTMR6	3027
CPNE7	3085
PLA2G4E	3334
MTMR2	3687
GDPD1	3859
PLAAT4	3914
OSBPL10	4165
PIK3R3	4324
SELENOI	4483
PCTP	4601
MTMR10	4619
MIGA1	4845
PIK3C2G	4876
SLC44A1	5089
PHOSPHO1	5096
AGK	5106
PITPNM3	5139
INPP5J	5214
RAB5A	5433
SLC44A3	5523
TNFAIP8L3	5656
PNPLA3	5711
SLC44A5	5859
BCHE	5967
TNFAIP8	6009
PIK3CD	6010
PIKFYVE	6155
ENPP6	6279
LIPI	6739
PIP4K2C	6872
PLA2G3	7310
PLAAT2	8134
GPAM	8224
TPTE2	8482
PLA2G10	8487
PLA2G2F	8995
PLA2G5	9231

---

REACTOME_RHOB_GTPASE_CYCLE

REACTOME_RHOB_GTPASE_CYCLE

	1369
set	REACTOME_RHOB_GTPASE_CYCLE
setSize	67
pANOVA	0.000456
s.dist	-0.248
p.adjustANOVA	0.0576

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF5	-11880
PREX1	-11127
PKN3	-10997
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
PKN1	-9980
MCAM	-9835
ARHGEF2	-9756
ACTC1	-9754
ANLN	-9294
MYO9B	-9163
ECT2	-9008
PIK3R1	-8469
SLK	-8352
ROCK1	-8181
IQGAP3	-7949
ABR	-7628
VANGL1	-7498
RHPN2	-7410

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF5	-11880
PREX1	-11127
PKN3	-10997
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
PKN1	-9980
MCAM	-9835
ARHGEF2	-9756
ACTC1	-9754
ANLN	-9294
MYO9B	-9163
ECT2	-9008
PIK3R1	-8469
SLK	-8352
ROCK1	-8181
IQGAP3	-7949
ABR	-7628
VANGL1	-7498
RHPN2	-7410
ARHGAP26	-7366
TFRC	-7152
ARHGAP1	-7025
BCR	-6531
FLOT2	-6527
JUP	-6376
PIK3R2	-6257
NET1	-5573
CIT	-5523
VAV2	-5410
ARHGEF10	-5092
ARHGEF17	-4965
STOM	-4867
AKAP13	-4682
ARHGAP21	-4511
FLOT1	-4439
ARHGEF1	-4410
MYO9A	-4177
DAAM1	-3726
DIAPH1	-3476
ARHGAP39	-2999
SOWAHC	-2812
ERBIN	-2546
ROCK2	-2459
VAMP3	-2222
TJP2	-2027
MCF2L	-1866
PKN2	-1812
RTKN	-903
ARHGAP35	-669
ARHGEF3	242
STARD13	344
ARHGEF28	410
DEPDC1B	418
PCDH7	517
ARHGDIG	2094
DIAPH3	2307
RHOB	2970
ARHGEF11	3152
DLC1	3276
ARHGEF12	3332
ARHGEF10L	4077
ARHGEF25	5241
ARHGAP5	5904
ARHGAP32	7862
SNAP23	7885
CAV1	8260

---

REACTOME_XENOBIOTICS

REACTOME_XENOBIOTICS

	435
set	REACTOME_XENOBIOTICS
setSize	22
pANOVA	0.000664
s.dist	0.419
p.adjustANOVA	0.0778

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2C19	9615.0
CYP3A5	9543.5
CYP2A13	9441.0
CYP2C9	9440.0
CYP3A4	8758.0
CYP2C18	8687.0
CYP2B6	8597.0
CYP2C8	8325.0
CYP1A1	7913.0
ARNT2	4944.0
CYP2J2	2860.0
CYP2W1	2847.0
AHR	1457.0
CYP2A7	1080.0
CYP2E1	676.0
CYP2F1	408.0
CYP3A7	-1097.0
ARNT	-1688.0
CYP1A2	-3364.0
CYP3A43	-3464.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2C19	9615.0
CYP3A5	9543.5
CYP2A13	9441.0
CYP2C9	9440.0
CYP3A4	8758.0
CYP2C18	8687.0
CYP2B6	8597.0
CYP2C8	8325.0
CYP1A1	7913.0
ARNT2	4944.0
CYP2J2	2860.0
CYP2W1	2847.0
AHR	1457.0
CYP2A7	1080.0
CYP2E1	676.0
CYP2F1	408.0
CYP3A7	-1097.0
ARNT	-1688.0
CYP1A2	-3364.0
CYP3A43	-3464.0
CYP2D6	-4218.0
CYP2S1	-4351.0

---

REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

	216
set	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS
setSize	14
pANOVA	0.000817
s.dist	0.517
p.adjustANOVA	0.0892

Top enriched genes

Top 20 genes

GeneID	Gene Rank
C1QB	9306
C1QA	9149
MASP1	8750
COLEC10	8491
FCN1	8247
C1S	8164
FCN2	6576
MASP2	5813
C1QC	4687
MBL2	4498
C1R	389
CRP	126
COLEC11	-272
FCN3	-10284

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
C1QB	9306
C1QA	9149
MASP1	8750
COLEC10	8491
FCN1	8247
C1S	8164
FCN2	6576
MASP2	5813
C1QC	4687
MBL2	4498
C1R	389
CRP	126
COLEC11	-272
FCN3	-10284

---

REACTOME_RHOA_GTPASE_CYCLE

REACTOME_RHOA_GTPASE_CYCLE

	1345
set	REACTOME_RHOA_GTPASE_CYCLE
setSize	142
pANOVA	0.000869
s.dist	-0.162
p.adjustANOVA	0.0892

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF5	-11880
PLEKHG4	-11600
PREX1	-11127
PKN3	-10997
RHOA	-10972
PLD1	-10696
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
ARHGEF18	-10202
PKN1	-9980
PGRMC2	-9912
STX5	-9876
MCAM	-9835
PLEKHG6	-9771
ARHGEF2	-9756
ACTC1	-9754
ANLN	-9294
ARAP1	-9230
MYO9B	-9163

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF5	-11880
PLEKHG4	-11600
PREX1	-11127
PKN3	-10997
RHOA	-10972
PLD1	-10696
CAVIN1	-10678
RACGAP1	-10526
STK10	-10434
ARHGEF18	-10202
PKN1	-9980
PGRMC2	-9912
STX5	-9876
MCAM	-9835
PLEKHG6	-9771
ARHGEF2	-9756
ACTC1	-9754
ANLN	-9294
ARAP1	-9230
MYO9B	-9163
ECT2	-9008
GMIP	-8602
PIK3R1	-8469
MACO1	-8426
SLK	-8352
ROCK1	-8181
IQGAP3	-7949
ARHGAP18	-7762
DDRGK1	-7736
ARHGAP29	-7729
ARHGEF19	-7725
ARHGAP11B	-7698
ABR	-7628
VANGL1	-7498
RHPN2	-7410
ARHGAP26	-7366
TFRC	-7152
ARHGAP1	-7025
ARHGAP23	-7015
BCR	-6531
FLOT2	-6527
VAV3	-6523
JUP	-6376
RHPN1	-6364
PIK3R2	-6257
AAAS	-6185
TEX2	-6145
TMEM87A	-6124
NET1	-5573
CIT	-5523
VAV2	-5410
ARHGEF7	-5104
ARHGEF10	-5092
LMAN1	-5039
ARHGEF17	-4965
EMC3	-4898
STOM	-4867
AKAP13	-4682
VAPB	-4633
ARAP3	-4556
ARHGAP21	-4511
ACBD5	-4475
FLOT1	-4439
ARHGEF1	-4410
IQGAP1	-4277
MYO9A	-4177
ARHGAP28	-4121
DAAM1	-3726
HMOX2	-3482
DOCK2	-3481
DIAPH1	-3476
SRGAP1	-3018
ARHGAP39	-2999
LBR	-2962
SOWAHC	-2812
ARHGAP45	-2786
ARHGEF40	-2699
ERBIN	-2546
PLEKHG3	-2525
ROCK2	-2459
FAF2	-2238
VAMP3	-2222
ARHGAP24	-2119
TJP2	-2027
ARHGAP10	-1992
OBSCN	-1917
MCF2L	-1866
PKN2	-1812
TMPO	-1808
ARAP2	-1708
FMNL3	-1625
FARP1	-1384
STBD1	-1269
ARHGAP20	-1200
RTKN	-903
ARHGAP35	-669
TAGAP	-420
ARHGDIA	-335
VAV1	-323
CCDC115	-87
ARHGEF3	242
FAM13A	276
STARD13	344
ARHGEF28	410
DEPDC1B	418
PCDH7	517
ARHGAP40	599
ARHGAP22	731
PREX2	931
ABCD3	1002
ARHGEF4	1055
NGEF	1185
PLEKHG5	1630
TRIO	1806
RASGRF2	2104
DIAPH3	2307
ARHGAP11A	2521
ARHGAP44	2594
ARHGAP9	2729
ARHGAP31	2987
ARHGEF11	3152
DLC1	3276
ARHGEF12	3332
DEF6	3729
ARHGEF10L	4077
SCFD1	4119
KALRN	4576
TIAM1	4715
C1QBP	4992
KTN1	5170
ARHGEF25	5241
ARHGAP5	5904
ARHGAP8	7109
ARHGAP19	7278
ARHGDIB	7447
ARHGAP42	7588
ARHGAP30	7842
ARHGAP32	7862
SNAP23	7885
ARHGEF15	7949
CAV1	8260
YKT6	8795

---

REACTOME_MEMBRANE_TRAFFICKING

REACTOME_MEMBRANE_TRAFFICKING

	374
set	REACTOME_MEMBRANE_TRAFFICKING
setSize	603
pANOVA	0.00122
s.dist	-0.0771
p.adjustANOVA	0.106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	-12026
SLC2A8	-11757
TOR1A	-11702
CHMP4A	-11522
PACSIN2	-11499
GRK2	-11491
ARF1	-11363
TBC1D13	-11361
SURF4	-11331
HPS1	-11320
RIN1	-11282
AGPAT3	-11261
TBC1D24	-11131
ASPSCR1	-11094
HPS4	-11090
YWHAB	-11084
ARFRP1	-11080
BIN1	-11025
PPP6R3	-11022
CTSZ	-10925

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	-12026
SLC2A8	-11757
TOR1A	-11702
CHMP4A	-11522
PACSIN2	-11499
GRK2	-11491
ARF1	-11363
TBC1D13	-11361
SURF4	-11331
HPS1	-11320
RIN1	-11282
AGPAT3	-11261
TBC1D24	-11131
ASPSCR1	-11094
HPS4	-11090
YWHAB	-11084
ARFRP1	-11080
BIN1	-11025
PPP6R3	-11022
CTSZ	-10925
AKT1	-10886
TBC1D2	-10801
AP1M1	-10791
CSNK1D	-10770
ULK1	-10702
DENND4B	-10655
SYNJ2	-10589
HGS	-10582
TRAPPC10	-10547
AKT2	-10544
KIFC2	-10529
RACGAP1	-10526
TBC1D20	-10498
DNM2	-10470
EPN1	-10465
DENND3	-10462
PREB	-10446
AP2A2	-10414
CD4	-10366
KIF2B	-10339
TBC1D10A	-10318
GJB3	-10306
RAB32	-10171
GOSR2	-10162
SBF1	-10143
TRAPPC2L	-10112
BLOC1S1	-10095
COPS5	-10067
DYNC1LI2	-10030
ARRB1	-10007
KIF5A	-10003
TSC2	-9932
RAB38	-9888
STX5	-9876
GALNT1	-9831
TUBA3C	-9788
TBC1D14	-9733
TUBB1	-9731
SRC	-9726
AREG	-9604
GAK	-9589
GJC2	-9514
VPS51	-9513
VPS4A	-9485
CHMP2A	-9473
SEC16A	-9376
DYNLL2	-9313
GGA1	-9302
VPS37B	-9256
AGFG1	-9249
TUBA1C	-9236
TGFA	-9233
AP1G2	-9166
CLTA	-9154
RAB35	-9152
GJB4	-9115
EXOC7	-9074
CLTB	-9039
TUBA3E	-8966
MON1B	-8900
LMAN1L	-8877
AVP	-8823
YWHAQ	-8800
ARF6	-8794
SERPINA1	-8752
GPS1	-8747
IGF2R	-8732
KIF1C	-8690
PLA2G6	-8669
PRKAB1	-8651
SEC31A	-8587
ARF3	-8585
EXOC8	-8501
KIF3C	-8474
ARFGAP2	-8462
ANKRD27	-8457
AP4M1	-8455
CD59	-8454
VPS25	-8439
LMAN2	-8427
CUX1	-8315
DCTN2	-8285
TMED10	-8244
SNX18	-8213
KIFC1	-8212
CLINT1	-8202
RAB5C	-8174
BICD2	-8144
EREG	-8140
SYT8	-8135
RIN3	-8121
PIP5K1C	-8119
RIC1	-8052
RAB27A	-7978
STAM2	-7929
YWHAE	-7851
RAB11B	-7842
DYNC1H1	-7804
TPD52	-7745
PRKAG2	-7718
ARFGAP1	-7715
TRAPPC12	-7709
GBF1	-7657
COG4	-7656
FNBP1	-7625
DCTN4	-7465
RAB6B	-7399
DTNBP1	-7360
VPS37C	-7326
PAFAH1B2	-7323
AP1B1	-7321
KIF12	-7318
NSF	-7297
TXNDC5	-7289
VPS52	-7223
ARPC1A	-7219
AP3B1	-7204
KLC1	-7189
TFRC	-7152
ARRB2	-7141
AP2M1	-7112
CHMP4C	-7109
MADD	-7059
PACSIN3	-7043
SNAP91	-7022
GORASP1	-6962
RABGAP1	-6953
USE1	-6880
GOLGB1	-6873
GOLGA2	-6845
TRAPPC13	-6806
RABEP1	-6739
EXOC2	-6721
STON1	-6704
COPA	-6640
WASL	-6596
ARFGAP3	-6592
TRIP10	-6543
COG3	-6530
TRAPPC9	-6509
KLC4	-6508
NAPG	-6394
SH3GL1	-6377
CALM1	-6248
HIP1R	-6184
KIF13B	-6162
CHRM2	-6157
COPS7B	-6154
KLC2	-6153
EXOC6	-6096
TBC1D16	-6085
TBC1D15	-6069
TMED3	-6010
GOLGA1	-5941
RAB18	-5919
KIF2C	-5909
CHMP2B	-5904
ANKRD28	-5892
SYT2	-5890
SNF8	-5874
MYO5A	-5866
TMED2	-5863
ACTR2	-5826
DAB2	-5814
RAB4A	-5793
MVB12B	-5780
DENND1C	-5772
GGA2	-5735
HBEGF	-5706
TBC1D1	-5667
HIP1	-5638
VTI1A	-5634
ACTR1A	-5584
COPS7A	-5567
KIF22	-5561
RHOBTB3	-5520
RAC1	-5471
MYO1C	-5402
COPE	-5379
GGA3	-5371
DNAJC6	-5344
RAB36	-5341
COPS6	-5338
CBL	-5273
VPS53	-5266
CYTH1	-5255
KIF2A	-5206
GALNT2	-5200
EPN2	-5166
SEC24B	-5148
COPZ1	-5093
TRAPPC6B	-5062
SNAP29	-5043
LMAN1	-5039
DENND1B	-5024
TSG101	-4903
RAB14	-4878
DENND6A	-4825
SPTAN1	-4822
DENND5A	-4768
CNIH3	-4703
KIF1A	-4665
DENND1A	-4655
MAN2A1	-4502
AP4E1	-4417
VPS28	-4397
RALGAPA2	-4396
SFN	-4372
MVB12A	-4286
KIF3B	-4282
TRAPPC1	-4197
RAB5B	-4193
COPS3	-4178
GOLGA5	-4150
SEC24C	-4094
VPS37D	-4048
VAMP8	-4047
TMED9	-4026
DNM3	-4015
GJB7	-4004
ACBD3	-3966
TOR1B	-3921
TRAPPC3	-3911
KDELR2	-3890
ARPC3	-3860
BLOC1S6	-3827
TRAPPC4	-3732
TUBB2A	-3682
DYNC1LI1	-3617
KIF20A	-3509
EPS15L1	-3473
RALA	-3346
COPB2	-3316
CPD	-3312
CHMP3	-3295
COPG1	-3289
RABGEF1	-3279
REPS1	-3271
SEC23IP	-3247
TRAPPC6A	-3225
DENND4C	-3218
DNM1	-3177
CAPZA2	-3154
COPS4	-3148
YWHAG	-3140
SEC22A	-3132
CNIH1	-3109
CLVS2	-3101
RAB10	-3046
GJD2	-2967
KIF16B	-2947
GCC2	-2928
AP1S1	-2838
PLIN3	-2830
CHMP6	-2715
YWHAH	-2710
GJB6	-2695
STX18	-2650
COG1	-2647
SH3GL2	-2631
AKT3	-2517
TMF1	-2510
AP1S3	-2481
CHMP4B	-2443
COPS8	-2428
BNIP1	-2426
LDLRAP1	-2324
ANK3	-2306
TUBA1A	-2281
VAMP3	-2222
GOLGA4	-2165
VPS36	-2164
AP2B1	-2137
SEC24D	-2117
ITSN1	-2089
FOLR1	-2084
RAB8A	-2070
ARPC2	-2036
STON2	-2017
MAP1LC3B	-2004
ITSN2	-1986
TJP1	-1974
EXOC4	-1961
GOSR1	-1952
ARCN1	-1947
NAA30	-1892
FZD4	-1854
RAB7A	-1836
KIF9	-1814
DENND6B	-1801
EXOC3	-1786
NAA35	-1669
TUBAL3	-1663
COG7	-1639
SPTBN1	-1621
EGFR	-1590
BET1L	-1567
STAM	-1561
COPG2	-1557
SYT11	-1525
TSC1	-1502
STX17	-1492
MAN2A2	-1488
KIF1B	-1478
RAB27B	-1477
GABARAPL2	-1455
ARF5	-1444
GJB2	-1375
FCHO1	-1356
RAB33B	-1349
LMAN2L	-1345
TRAPPC8	-1336
VPS54	-1322
SCARB2	-1306
GABARAP	-1294
KIF20B	-1285
MIA2	-1228
MAN1A2	-1170
MIA3	-1128
LDLR	-1067
AP4B1	-945
USP6NL	-944
AAK1	-922
FCHO2	-916
RAB3A	-912
NECAP2	-886
RAB11A	-847
SNX2	-788
KIF21B	-758
HSPA8	-751
STX6	-725
TUBA4B	-707
CLTCL1	-661
CYTH3	-629
SBF2	-536
EPGN	-505
WNT5A	-457
TBC1D7	-442
DYNC1I2	-374
COG5	-300
TMEM115	-287
RAB6A	-286
BLOC1S4	-206
SYNJ1	-178
KIF25	-167
YWHAZ	-146
PRKAG3	-137
ACTR3	-130
DENND2A	-110
RAB31	-104
ALS2	-102
KIF18B	-98
ARFIP2	0
DYNLL1	26
DCTN1	60
RGP1	64
SPTBN4	74
KIF5B	190
SYT9	198
GCC1	228
PPP6R1	248
SLC2A4	303
EXOC5	307
VPS4B	311
UBQLN1	328
KIF27	338
SEC22C	353
TUBB6	387
PRKAG1	401
KDELR1	413
STX4	432
BICD1	442
AGTR1	484
CLTC	529
CAPZA1	546
SPTB	606
SYS1	615
TACR1	692
PPP6C	723
ZW10	752
GRK3	757
RAB43	796
KIF26A	873
MYH9	883
RALGAPB	908
OPTN	913
COL7A1	936
APP	942
TUBA4A	1016
AP3S1	1051
SEC23A	1053
PUM1	1056
COG8	1061
GJD3	1096
SPTA1	1100
SNX9	1160
KIF23	1192
STX10	1254
TUBA1B	1291
DCTN3	1324
LNPEP	1375
DENND4A	1408
MON1A	1411
PICALM	1483
MAN1A1	1485
TBC1D10B	1494
CHMP7	1498
TUBA8	1565
KIF15	1595
KIAA0319	1674
CNIH2	1707
TUBB8	1769
TMED7	1779
NAPA	1853
RAB3GAP1	1867
ANK2	1944
MCFD2	1949
AP2A1	1991
STX16	1994
DENND2C	2063
APOB	2093
ARL1	2107
COG2	2126
TRIP11	2181
PRKAA2	2223
PLA2G4A	2243
SLC18A3	2277
CYTH2	2346
NBAS	2384
RAB1B	2396
SPTBN5	2404
USO1	2420
KIF19	2480
VTA1	2501
KIF26B	2502
KIF18A	2526
PAFAH1B1	2571
ACTG1	2573
COG6	2574
CTTN	2608
PIK3C2A	2634
SNX5	2664
C2CD5	2707
MYO6	2826
TUBB4A	2909
RINT1	2945
RHOQ	3006
GJA1	3042
TUBB3	3143
MAN1C1	3148
SH3GL3	3157
GAPVD1	3219
SORT1	3232
RAB3IP	3308
VAMP4	3348
PAFAH1B3	3357
ALPP	3374
KIF11	3432
AMPH	3465
SAR1B	3547
UBAP1	3559
TFG	3563
VPS37A	3587
NAPB	3648
SYTL1	3666
TRAPPC5	3682
ANK1	3694
F5	3783
CHMP5	3826
RIN2	3851
AP1G1	3910
DVL2	3968
GJD4	4007
GJC1	4014
EXOC1	4049
CAPZB	4075
SCFD1	4119
DENND5B	4139
KLC3	4184
EGF	4243
DYNC1I1	4409
DNASE2	4457
RAB3GAP2	4503
ALS2CL	4513
ADRB2	4529
SGIP1	4532
TBC1D4	4543
RAB13	4624
SEC22B	4626
STXBP3	4656
FTL	4671
AP1M2	4681
DCTN5	4684
EPS15	4747
KIFAP3	4842
TBC1D17	4983
TRAPPC11	5030
ARPC5	5098
LRP2	5099
VPS45	5107
CTSC	5130
SCOC	5133
GJA3	5191
BET1	5206
ARPC4	5323
KIF3A	5389
TPD52L1	5404
RAB5A	5433
PRKAB2	5526
GNS	5528
SEC13	5529
AP4S1	5533
BLOC1S3	5584
DENND2B	5587
PACSIN1	5594
SYT1	5622
DCTN6	5635
SPTBN2	5686
RABEPK	5852
NEDD8	5890
RAB8B	5905
CLVS1	5978
GOLIM4	6000
CYTH4	6072
ACTB	6120
NAA38	6132
SH3D19	6137
RPS27A	6202
VAMP2	6211
CD55	6247
DENND2D	6323
SNAPIN	6386
BTC	6417
TGOLN2	6423
AP2S1	6513
COPB1	6688
ACTR10	6689
INS	6732
KIF6	6733
GJA10	6828
SEC24A	6864
RAB30	6927
GRB2	6943
TUBB2B	6990
UBA52	7023
KIF4B	7316
TUBB4B	7335
CENPE	7359
RAB21	7366
RAB3IL1	7383
UBC	7391
COPS2	7523
ARF4	7562
NECAP1	7576
RAB1A	7620
SEC16B	7694
KIF21A	7816
RINL	7821
FTH1	7833
CFTR	7876
SNAP23	7885
FNBP1L	7920
TF	7948
UBB	8218
RAB12	8283
M6PR	8301
GDI2	8312
GJA8	8358
CAPZA3	8517
COPZ2	8567
GJA5	8674
KDELR3	8719
GJB5	8775
YKT6	8795
GJA9	8820
RAB39A	8923
GJA4	9056
GRIA1	9139
CHML	9497
TBC1D10C	9599
IL7R	9617
CD3G	9855
CD3D	9867

---

REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS

REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS

	789
set	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS
setSize	62
pANOVA	0.00127
s.dist	-0.237
p.adjustANOVA	0.106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
AMDHD2	-11555
ST3GAL4	-11197
ST3GAL6	-10924
GMPPA	-10480
NEU2	-10268
PMM2	-9960
DPM1	-9801
ST3GAL2	-9798
ST8SIA3	-9601
MVD	-9581
NPL	-9262
NUDT14	-9194
SRD5A3	-8754
SLC35C1	-8564
UAP1	-8507
GFUS	-8162
ST6GALNAC6	-8105
GMPPB	-7894
PMM1	-7757
DOLPP1	-7586

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
AMDHD2	-11555
ST3GAL4	-11197
ST3GAL6	-10924
GMPPA	-10480
NEU2	-10268
PMM2	-9960
DPM1	-9801
ST3GAL2	-9798
ST8SIA3	-9601
MVD	-9581
NPL	-9262
NUDT14	-9194
SRD5A3	-8754
SLC35C1	-8564
UAP1	-8507
GFUS	-8162
ST6GALNAC6	-8105
GMPPB	-7894
PMM1	-7757
DOLPP1	-7586
FCSK	-7472
DHDDS	-7131
DPM3	-6760
CMAS	-6173
GLB1	-6067
NEU1	-6004
ST6GALNAC2	-5883
CTSA	-5671
ST8SIA5	-5352
NUS1	-5279
DOLK	-5122
GMDS	-4621
FUOM	-4357
ALG5	-3844
GNE	-3830
NEU4	-2846
FPGT	-2768
ST3GAL1	-2708
NANP	-2598
NAGK	-2480
GFPT2	-2053
ST6GAL2	-1781
ST3GAL3	-1475
NANS	-1176
ST6GALNAC5	-33
GFPT1	756
SLC35A1	912
NEU3	1259
DPM2	1632
ST3GAL5	1646
ST8SIA6	1969
GNPNAT1	1971
ST6GALNAC4	2129
ST8SIA4	3299
ST6GAL1	3359
ST6GALNAC3	3722
SLC17A5	4039
MPI	4161
ST8SIA2	5694
ST8SIA1	6609
PGM3	6720
ST6GALNAC1	9180

---

REACTOME_TCR_SIGNALING

REACTOME_TCR_SIGNALING

	391
set	REACTOME_TCR_SIGNALING
setSize	113
pANOVA	0.00128
s.dist	0.175
p.adjustANOVA	0.106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
GRAP2	9593
TRAT1	9322
LCK	9316
ITK	8970
HLA-DRA	8538
PTPRC	8483
PSMB3	8251
UBB	8218
PSMC2	8147
PSMB5	8115
PLCG1	8112
LAT	8043
LCP2	7873
UBC	7391
PSME2	7312
UBA52	7023
ENAH	7000

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
GRAP2	9593
TRAT1	9322
LCK	9316
ITK	8970
HLA-DRA	8538
PTPRC	8483
PSMB3	8251
UBB	8218
PSMC2	8147
PSMB5	8115
PLCG1	8112
LAT	8043
LCP2	7873
UBC	7391
PSME2	7312
UBA52	7023
ENAH	7000
PSMA4	6896
PAG1	6645
HLA-DPB1	6475
MAP3K7	6414
RPS27A	6202
BTRC	5660
CD247	5640
PSMB1	5600
PSMA6	5015
CD101	4962
EVL	4855
PSMB4	4570
PSMA7	4493
PSMB8	4390
HLA-DQA1	4376
PSMD7	4369
RIPK2	4343
PSMC6	4259
BCL10	4080
PSMA2	3743
PSMC5	3651
UBE2V1	3562
PSMD3	3550
HLA-DRB5	3407
CSK	3354
PSMD14	3291
NFKBIA	3202
ZAP70	3178
NFKB1	3151
PSME3	2934
PRKCQ	2767
HLA-DQA2	2476
PTEN	2245
PSMD11	2103
UBE2D1	2022
PIK3CA	2017
UBE2D2	1756
PSMD12	1473
VASP	1418
PAK1	1260
FYB1	684
PSME1	574
HLA-DRB1	520
PSMC3	511
HLA-DQB2	507
PSMD9	385
PSMA1	206
PSMA8	45
PSMA3	-63
PSMC4	-326
PSMB6	-534
IKBKB	-552
UBE2N	-700
PSMD6	-1201
SEM1	-1346
PSMA5	-2270
PSMB11	-2381
MALT1	-2471
PTPN22	-2643
PIK3CB	-3260
HLA-DQB1	-3560
PSMB9	-3711
PSMB10	-3782
PSMF1	-3800
PSMC1	-4003
CHUK	-4213
PSMD1	-4322
PSMD4	-4377
PSMD5	-4468
PSMB2	-4485
PLCG2	-4748
SKP1	-5130
PSMD13	-5161
NCK1	-5559
PAK2	-5763
CUL1	-5886
FBXW11	-6050
PIK3R2	-6257
PSME4	-6624
HLA-DPA1	-7387
PSMD8	-7863
TAB2	-7994
PSMB7	-8167
PIK3R1	-8469
PTPRJ	-8552
RELA	-9312
CARD11	-9331
PSMD2	-10038
PDPK1	-10204
TRAF6	-10304
CD4	-10366
INPP5D	-10722
CDC34	-11430

---

REACTOME_SIGNALING_BY_VEGF

REACTOME_SIGNALING_BY_VEGF

	339
set	REACTOME_SIGNALING_BY_VEGF
setSize	102
pANOVA	0.00129
s.dist	-0.184
p.adjustANOVA	0.106

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RHOA	-10972
AKT1	-10886
HRAS	-10751
AKT2	-10544
CDH5	-10425
VEGFB	-10231
PDPK1	-10204
NCF2	-10203
MLST8	-10183
CTNND1	-10123
CYFIP1	-10047
PRKACA	-9870
MAPKAPK3	-9830
SRC	-9726
ITPR3	-9355
NRAS	-9345
PXN	-8993
NCF4	-8612
MAPKAPK2	-8608
PIK3R1	-8469

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RHOA	-10972
AKT1	-10886
HRAS	-10751
AKT2	-10544
CDH5	-10425
VEGFB	-10231
PDPK1	-10204
NCF2	-10203
MLST8	-10183
CTNND1	-10123
CYFIP1	-10047
PRKACA	-9870
MAPKAPK3	-9830
SRC	-9726
ITPR3	-9355
NRAS	-9345
PXN	-8993
NCF4	-8612
MAPKAPK2	-8608
PIK3R1	-8469
NCKAP1L	-8389
MTOR	-8301
ROCK1	-8181
BAIAP2	-7933
KRAS	-7903
PRKCD	-7879
BRK1	-7841
ITPR1	-7839
PRKCZ	-7754
VEGFA	-7397
CDC42	-7164
VAV3	-6523
SH2D2A	-6426
JUP	-6376
PIK3R2	-6257
CALM1	-6248
TRIB3	-6043
ELMO1	-6023
ITPR2	-5932
PAK2	-5763
SHB	-5647
NCK1	-5559
RAC1	-5471
VAV2	-5410
MAPK11	-5323
ELMO2	-5259
SHC2	-4951
RICTOR	-4636
ABI2	-4422
FLT4	-4140
PIK3CB	-3260
RASA1	-3259
FLT1	-3229
CYFIP2	-3066
ITGAV	-3056
PTK2B	-2883
CRK	-2873
CTNNB1	-2706
AKT3	-2517
ROCK2	-2459
DOCK1	-1837
PRKCA	-1822
MAPK14	-1601
PRKCB	-1454
WASF2	-1372
NCKAP1	-1320
NCK2	-1242
SPHK1	-1134
PRR5	-962
MAPKAP1	-935
WASF3	-686
CYBA	-592
FYN	-487
ABI1	-466
VAV1	-323
CTNNA1	230
NRP1	305
HSP90AA1	563
THEM4	1054
PAK1	1260
AAMP	1346
BCAR1	1380
WASF1	1436
PIK3CA	2017
AHCYL1	2482
ACTG1	2573
PGF	2820
NOS3	2969
ITGB3	3419
MAPK13	5346
HSPB1	5538
ACTB	6120
NRP2	6126
PTK2	6296
PRKACB	6462
PRKACG	7445
MAPK12	7473
VEGFC	7479
AXL	7541
KDR	8072
PLCG1	8112
CAV1	8260

---

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

	1082
set	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE
setSize	125
pANOVA	0.00143
s.dist	0.165
p.adjustANOVA	0.11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LCE2D	9810
LCE3D	9787
KRT23	9635
LCE2C	9555
SPRR3	9509
DSC1	9388
IVL	9305
LCE4A	9194
LELP1	9165
DSG1	9164
KRT6C	9161
KRT76	9109
DSG4	9070
RPTN	9018
KRT14	8961
LCE1E	8959
SPINK5	8925
LCE6A	8910
KRT40	8851
SPRR2A	8605

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LCE2D	9810
LCE3D	9787
KRT23	9635
LCE2C	9555
SPRR3	9509
DSC1	9388
IVL	9305
LCE4A	9194
LELP1	9165
DSG1	9164
KRT6C	9161
KRT76	9109
DSG4	9070
RPTN	9018
KRT14	8961
LCE1E	8959
SPINK5	8925
LCE6A	8910
KRT40	8851
SPRR2A	8605
SPRR2G	8604
KRT33A	8459
LCE1C	8396
KRT9	8384
KRT37	8352
KRT35	8285
KRT15	8274
PKP1	8071
KRT4	7998
LCE5A	7984
LIPK	7884
LCE1A	7697
CASP14	7494
KLK12	7384
LCE2A	7338
KRT75	7252
CDSN	7028
KRT19	6770
KRT86	6616
SPRR2E	6467
KRT38	6392
FLG	6382
LCE3B	6339
KRT39	6214
DSP	6013
SPRR2F	5606
SPRR1B	4916
PRSS8	4635
LCE3E	4347
KRT73	4327
DSG2	4141
KLK5	4003
KRT6B	3873
KRT83	3792
KRT32	3760
KRT74	3646
PCSK6	3622
ST14	3570
TCHH	3514
KRT10	3394
KRT16	2701
KAZN	2366
KRT2	2340
KRT7	2132
KRT79	2114
KRT82	1785
LCE1F	1720
KRT78	1035
KRT5	900
PKP2	847
PERP	556
KRT71	169
KRT81	85
KRT27	69
DSG3	-96
SPRR2D	-453
KRT34	-802
SPINK6	-1077
SPINK9	-1195
KRT84	-1909
KLK13	-2196
KRT1	-2327
KRT3	-3230
LCE1B	-3754
KRT28	-3998
KRT20	-4101
LIPN	-4310
KRT72	-4429
PI3	-4967
PKP4	-5476
LCE2B	-5524
KRT77	-6341
JUP	-6376
SPRR1A	-6506
CAPN1	-6557
KRT24	-7484
LIPM	-7485
CAPNS1	-7520
KRT80	-7979
LIPJ	-8149
CELA2A	-8318
KRT18	-8633
DSC2	-8635
TGM5	-8709
KLK8	-8791
KRT85	-8858
KRT13	-8991
PKP3	-9260
KRT31	-9436
EVPL	-9533
KRT6A	-9538
KLK14	-9911
DSC3	-9944
KRT36	-10001
KRT12	-10567
KRT26	-10650
CSTA	-10905
PPL	-10978
KRT33B	-11005
KRT8	-11273
KRT17	-11412
FURIN	-11533
LCE3A	-11590
TGM1	-11599
KRT25	-11842

---

REACTOME_RHO_GTPASE_CYCLE

REACTOME_RHO_GTPASE_CYCLE

	1368
set	REACTOME_RHO_GTPASE_CYCLE
setSize	423
pANOVA	0.00147
s.dist	-0.0901
p.adjustANOVA	0.11

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ARHGEF5	-11880
PLEKHG4	-11600
PREX1	-11127
PKN3	-10997
RHOA	-10972
DOCK6	-10904
TPM4	-10880
PARD6B	-10848
PLD1	-10696
CAVIN1	-10678
VANGL2	-10613
HGS	-10582
RACGAP1	-10526
SRGAP2	-10441
STK10	-10434
EFHD2	-10225
NCF2	-10203
ARHGEF18	-10202
SLC1A5	-10165
STK38	-10155

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ARHGEF5	-11880.0
PLEKHG4	-11600.0
PREX1	-11127.0
PKN3	-10997.0
RHOA	-10972.0
DOCK6	-10904.0
TPM4	-10880.0
PARD6B	-10848.0
PLD1	-10696.0
CAVIN1	-10678.0
VANGL2	-10613.0
HGS	-10582.0
RACGAP1	-10526.0
SRGAP2	-10441.0
STK10	-10434.0
EFHD2	-10225.0
NCF2	-10203.0
ARHGEF18	-10202.0
SLC1A5	-10165.0
STK38	-10155.0
GFOD1	-10098.0
CYFIP1	-10047.0
PKN1	-9980.0
CUL3	-9965.0
GIT1	-9920.0
PGRMC2	-9912.0
PARD6A	-9890.5
STX5	-9876.0
MCAM	-9835.0
PLEKHG6	-9771.0
ARHGEF2	-9756.0
ACTC1	-9754.0
TRA2B	-9745.0
SRC	-9726.0
KCTD13	-9663.0
NDUFS3	-9549.0
ANLN	-9294.0
SLITRK3	-9275.0
ANKLE2	-9272.0
ARAP1	-9230.0
MYO9B	-9163.0
ITGB1	-9073.0
ESYT1	-9061.0
STEAP3	-9042.0
ECT2	-9008.0
ARHGAP17	-8957.0
RND2	-8865.0
FARP2	-8827.0
GPS1	-8747.0
WDR81	-8721.0
CKB	-8697.0
NCF4	-8612.0
GMIP	-8602.0
PIK3R1	-8469.0
ARFGAP2	-8462.0
PAK4	-8450.0
MACO1	-8426.0
NCKAP1L	-8389.0
SLK	-8352.0
CPNE8	-8237.0
RAC3	-8230.0
FAM169A	-8201.0
ARHGAP33	-8188.0
RHOG	-8185.0
ROCK1	-8181.0
SPEN	-8099.0
PLEKHG2	-8089.0
VCP	-8043.0
IQGAP3	-7949.0
BAIAP2	-7933.0
STAM2	-7929.0
BRK1	-7841.0
FERMT2	-7831.0
WWP2	-7765.0
ARHGAP18	-7762.0
DDRGK1	-7736.0
ARHGAP29	-7729.0
ARHGEF19	-7725.0
ARHGAP11B	-7698.0
DDX39B	-7629.0
ABR	-7628.0
FNBP1	-7625.0
MTR	-7507.0
VANGL1	-7498.0
RND3	-7436.0
RHPN2	-7410.0
MSI2	-7392.0
ARHGAP26	-7366.0
NUDC	-7335.0
TAOK3	-7221.0
SLITRK5	-7175.0
CDC42	-7164.0
TFRC	-7152.0
PHIP	-7103.0
NISCH	-7083.0
ARHGAP1	-7025.0
GOLGA3	-7023.0
LRRC1	-7017.0
ARHGAP23	-7015.0
PLXND1	-6625.0
WASL	-6596.0
ARFGAP3	-6592.0
TRIP10	-6543.0
BCR	-6531.0
FLOT2	-6527.0
VAV3	-6523.0
JUP	-6376.0
RHPN1	-6364.0
ZNF512B	-6357.0
IQGAP2	-6291.0
SRRM1	-6266.0
PIK3R2	-6257.0
CPSF7	-6255.0
SOS1	-6228.0
AAAS	-6185.0
ANKFY1	-6176.0
DOCK3	-6155.0
TEX2	-6145.0
RALBP1	-6130.0
TMEM87A	-6124.0
WDR91	-6091.0
CDC42EP2	-6084.0
FGD3	-6068.0
WIPF2	-5943.0
SHKBP1	-5917.0
DOCK8	-5851.0
PAK2	-5763.0
FRS3	-5633.0
BLTP3B	-5587.0
LAMTOR1	-5574.0
NET1	-5573.0
NCK1	-5559.0
CIT	-5523.0
PKP4	-5476.0
RAC1	-5471.0
WIPF1	-5465.0
VAV2	-5410.0
PLXNA1	-5378.0
ELMO2	-5259.0
DLG5	-5220.0
ARHGEF7	-5104.0
ARHGEF10	-5092.0
PLD2	-5090.0
GNA13	-5076.0
LMAN1	-5039.0
SYDE1	-4999.0
ARHGEF17	-4965.0
MAP3K11	-4957.0
EMC3	-4898.0
STOM	-4867.0
SPTAN1	-4822.0
AKAP13	-4682.0
VAPB	-4633.0
ARAP3	-4556.0
CKAP4	-4522.0
ARHGAP21	-4511.0
DOCK5	-4496.0
ACBD5	-4475.0
FLOT1	-4439.0
ABI2	-4422.0
ARHGEF1	-4410.0
NOXA1	-4354.0
EPHA2	-4298.0
IQGAP1	-4277.0
WHAMM	-4268.0
GIT2	-4248.0
ARHGEF26	-4184.0
MYO9A	-4177.0
ARHGAP28	-4121.0
BASP1	-3948.0
CCDC88A	-3840.0
DAAM1	-3726.0
BAIAP2L2	-3719.0
JAG1	-3708.0
SCRIB	-3674.0
SWAP70	-3638.0
FAM135A	-3529.0
HMOX2	-3482.0
DOCK2	-3481.0
DIAPH1	-3476.0
DNMBP	-3394.0
VRK2	-3354.0
FAM91A1	-3322.0
CPD	-3312.0
FGD4	-3233.0
ARHGAP27	-3204.0
COPS4	-3148.0
RNF20	-3138.0
CYFIP2	-3066.0
LEMD3	-3030.0
HSPE1	-3019.0
SRGAP1	-3018.0
PRAG1	-3013.0
ARHGAP39	-2999.0
LBR	-2962.0
PTK2B	-2883.0
SOWAHC	-2812.0
ARHGAP45	-2786.0
HNRNPC	-2737.0
ARHGEF40	-2699.0
PTPN13	-2670.0
WIPF3	-2581.0
ERBIN	-2546.0
LETM1	-2527.0
PLEKHG3	-2525.0
ROCK2	-2459.0
GOPC	-2392.0
CDC42BPB	-2386.0
CCT7	-2338.0
RHOU	-2309.0
TMEM59	-2265.0
TNFAIP1	-2260.0
FAF2	-2238.0
VAMP3	-2222.0
FMNL2	-2212.0
ARHGAP24	-2119.0
ITSN1	-2089.0
TJP2	-2027.0
ARHGAP10	-1992.0
ITSN2	-1986.0
OBSCN	-1917.0
MCF2L	-1866.0
DOCK1	-1837.0
RAB7A	-1836.0
PKN2	-1812.0
TMPO	-1808.0
SAMM50	-1778.0
ARAP2	-1708.0
FMNL3	-1625.0
SPTBN1	-1621.0
STAM	-1561.0
KIDINS220	-1536.0
RHOV	-1528.0
CDC37	-1510.0
FARP1	-1384.0
WASF2	-1372.0
PLXNB1	-1330.0
NCKAP1	-1320.0
NSFL1C	-1297.0
STBD1	-1269.0
NCK2	-1242.0
ARHGAP20	-1200.0
CCT2	-1182.0
FAM13B	-1135.0
DBT	-1133.0
RTKN	-903.0
OSBPL11	-900.0
UACA	-875.0
DOCK7	-750.0
SLC4A7	-709.0
WASF3	-686.0
SOS2	-671.0
ARHGAP35	-669.0
RRAS2	-618.0
UBXN11	-617.0
CHN2	-604.0
CYBA	-592.0
ARHGAP12	-563.0
MPP7	-547.0
RAPGEF1	-467.0
ABI1	-466.0
TAGAP	-420.0
RAC2	-415.0
ARHGDIA	-335.0
VAV1	-323.0
SH3RF1	-303.0
WDR11	-220.0
PDE5A	-196.0
ALS2	-102.0
CCDC115	-87.0
NIPSNAP2	5.0
KIF14	97.0
ARHGAP25	124.0
PLEKHG4B	131.0
TWF1	157.0
ARHGEF3	242.0
CDC42SE2	267.0
FAM13A	276.0
STARD13	344.0
ALDH3A2	347.0
FGD2	390.0
ARHGEF28	410.0
DEPDC1B	418.0
SHMT2	436.0
CDC42EP3	463.0
SYDE2	483.0
PCDH7	517.0
CLTC	529.0
HSP90AA1	563.0
ARHGAP40	599.0
EPSTI1	641.0
DOCK9	702.0
ARHGAP22	731.0
ABL2	736.0
DOCK10	761.0
AKAP12	919.0
PREX2	931.0
RHOBTB1	961.0
ABCD3	1002.0
ARHGAP15	1019.0
ARHGEF4	1055.0
NGEF	1185.0
PAK1	1260.0
TUBA1B	1291.0
CDC42BPA	1300.0
PEAK1	1325.0
WASF1	1436.0
FRS2	1458.0
PICALM	1483.0
FMNL1	1516.0
ANKRD26	1558.0
PLEKHG5	1630.0
RALGAPA1	1663.0
SH3BP1	1749.0
TRIO	1806.0
TPM3	1972.0
PIK3CA	2017.0
PAK5	2054.0
GARRE1	2083.0
ARHGDIG	2094.0
RASGRF2	2104.0
NDUFA5	2149.0
HINT2	2235.0
HSP90AB1	2253.0
RHOBTB2	2273.0
VIM	2293.0
DIAPH3	2307.0
LMNB1	2321.0
CEP97	2328.0
BAIAP2L1	2411.0
ARHGAP11A	2521.0
ACTG1	2573.0
ARHGAP44	2594.0
ARHGAP9	2729.0
MYO6	2826.0
FAM83B	2876.0
RHOB	2970.0
ARHGAP31	2987.0
RHOQ	3006.0
ACTN1	3023.0
GJA1	3042.0
CDC42EP4	3116.0
ARHGEF11	3152.0
ZAP70	3178.0
DLC1	3276.0
ARHGEF12	3332.0
CSK	3354.0
CCT6A	3430.0
ARHGEF16	3461.0
DOCK4	3500.0
FGD5	3516.0
RHOF	3620.0
ADD3	3669.0
DEF6	3729.0
PLEKHG1	3789.0
TMOD3	3820.0
WDR6	3977.0
TIAM2	4047.0
STMN2	4063.0
CAPZB	4075.0
ARHGEF10L	4077.0
SCFD1	4119.0
DSG2	4141.0
SPATA13	4148.0
RASAL2	4218.0
CCP110	4250.0
GRB7	4264.0
PIK3R3	4324.0
TXNL1	4366.0
RHOJ	4455.0
POTEE	4476.0
KALRN	4576.0
MTX1	4706.0
TIAM1	4715.0
SH3PXD2A	4740.0
STIP1	4898.0
RBBP6	4987.0
C1QBP	4992.0
DBN1	4995.0
KTN1	5170.0
RND1	5189.0
PAK6	5228.0
ARHGEF25	5241.0
DDX4	5264.0
ARL13B	5290.0
KCTD3	5543.0
SRGAP3	5800.0
ARHGAP5	5904.0
DST	5982.0
DSP	6013.0
CHN1	6091.0
ACTB	6120.0
SENP1	6187.0
TOR1AIP1	6206.0
RHOD	6750.0
RHOC	6854.0
GRB2	6943.0
FILIP1	7083.0
ARHGAP8	7109.0
AMIGO2	7179.0
ARHGAP19	7278.0
ARHGEF39	7279.0
NOXO1	7385.0
ARHGDIB	7447.0
COPS2	7523.0
ARHGAP42	7588.0
MUC13	7805.0
SEMA4F	7830.0
ARHGAP30	7842.0
ARHGAP32	7862.0
CFTR	7876.0
SNAP23	7885.0
FNBP1L	7920.0
ARHGEF15	7949.0
CDC42EP1	8007.0
RHOH	8152.0
CAV1	8260.0
IL32	8314.0
NOX3	8735.0
CDC42EP5	8763.0
YKT6	8795.0
DSG1	9164.0
LCK	9316.0

---

REACTOME_DRUG_ADME

REACTOME_DRUG_ADME

	1593
set	REACTOME_DRUG_ADME
setSize	103
pANOVA	0.00202
s.dist	0.176
p.adjustANOVA	0.144

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GSTA2	9816
CYP2C19	9615
ADH1A	9596
GSTA1	9554
ACSM4	9534
CYP2C9	9440
PON1	9209
ACSM2A	9029
CYP3A4	8758
SULT1A1	8614
AKR1C1	8495
NAT2	8421
CYP2C8	8325
UGT2B7	7929
SLC22A8	7313
GLYATL3	7263
GLYAT	7053
HSD11B1	6848
UGT2B4	6754
UGT2B11	6737

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GSTA2	9816
CYP2C19	9615
ADH1A	9596
GSTA1	9554
ACSM4	9534
CYP2C9	9440
PON1	9209
ACSM2A	9029
CYP3A4	8758
SULT1A1	8614
AKR1C1	8495
NAT2	8421
CYP2C8	8325
UGT2B7	7929
SLC22A8	7313
GLYATL3	7263
GLYAT	7053
HSD11B1	6848
UGT2B4	6754
UGT2B11	6737
SLC28A2	6694
GLYATL1	6659
PNP	6479
SLCO1B1	6349
UGT1A3	6311
SLCO1B3	6125
BCHE	5967
UGT1A10	5546
UGT1A8	5490
ADK	5441
ADAL	5399
UGT1A7	5370
PON3	5337
UGT1A9	5210
UGT2B15	5178
SLC28A3	5140
ABCC2	5010
SULT1E1	4912
UGT1A4	4750
IMPDH2	4456
NUDT15	4425
ALB	4370
UGT1A6	4015
SULT2A1	3679
UGT2A1	3483
UGT3A1	3215
UGT1A5	2913
PCK1	2796
UGT2A2	2619
CES2	2397
SLC22A7	2226
UGT1A1	2139
SLC22A1	1818
ABCC5	1715
ACSM5	1529
SLC22A2	1333
XDH	1198
CYP2E1	676
ABCG2	493
SLC29A1	318
UGT3A2	-275
VAV1	-323
CES1	-660
ABCB1	-1047
SULT1C4	-1706
NME2	-1941
ABCC4	-2611
GGT6	-2799
NAT1	-3453
SLCO2B1	-3865
ACY1	-3978
CYP2D6	-4218
BSG	-4269
GUK1	-4275
TPMT	-4346
GSTP1	-4595
UGT2A3	-4607
HSD11B2	-4699
SLC16A1	-4820
ADA	-5127
ABCC3	-5165
CNDP2	-5276
VAV2	-5410
RAC1	-5471
NT5C2	-6244
SERPINA6	-6373
VAV3	-6523
NME1	-6701
SLCO1A2	-6777
GMPS	-6802
GSTM1	-7009
SLC22A3	-7230
GLYATL2	-8693
UGT2B17	-8880
GGT1	-9308
IMPDH1	-9440
SLC29A2	-9615
SLC29A3	-9664
GGT5	-10147
GGT7	-10212
ACSM2B	-10230
ABCC1	-10504
ITPA	-10532

---

REACTOME_LEISHMANIA_INFECTION

REACTOME_LEISHMANIA_INFECTION

	1509
set	REACTOME_LEISHMANIA_INFECTION
setSize	156
pANOVA	0.0024
s.dist	-0.141
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FCGR3A	-11998
DVL3	-11552
FURIN	-11533
GNB1	-11404
HMOX1	-11301
ADORA2B	-11046
NCKIPSD	-11007
MAPK3	-10990
ADCY4	-10862
P2RX4	-10742
CTSG	-10716
ADCY7	-10573
GGT5	-10147
FCGR2A	-10113
P2RX7	-10082
CYFIP1	-10047
C3	-9967
GNG5	-9946
GNAI2	-9906
PRKACA	-9870

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FCGR3A	-11998
DVL3	-11552
FURIN	-11533
GNB1	-11404
HMOX1	-11301
ADORA2B	-11046
NCKIPSD	-11007
MAPK3	-10990
ADCY4	-10862
P2RX4	-10742
CTSG	-10716
ADCY7	-10573
GGT5	-10147
FCGR2A	-10113
P2RX7	-10082
CYFIP1	-10047
C3	-9967
GNG5	-9946
GNAI2	-9906
PRKACA	-9870
SRC	-9726
GNG3	-9620
ARPC1B	-9607
ITPR3	-9355
RELA	-9312
GGT1	-9308
DVL1	-9299
MYO9B	-9163
DPEP1	-9087
MEFV	-8959
PRKAR1A	-8424
NCKAP1L	-8389
BAIAP2	-7933
BRK1	-7841
ITPR1	-7839
MAPK1	-7647
PRKAR1B	-7414
LYN	-7353
ARPC1A	-7219
CDC42	-7164
ADCY9	-7087
IL10	-6869
ADCY6	-6804
CREB1	-6716
WASL	-6596
VAV3	-6523
GNG2	-6362
CALM1	-6248
ADAM17	-6210
GNG4	-6103
ELMO1	-6023
GNB5	-5958
WIPF2	-5943
ITPR2	-5932
GNAS	-5876
MYO5A	-5866
ACTR2	-5826
TXN	-5656
YES1	-5599
GNG13	-5594
NCK1	-5559
RAC1	-5471
WIPF1	-5465
VAV2	-5410
MYO1C	-5402
CYSLTR2	-5384
NLRP3	-5298
ELMO2	-5259
ABL1	-5137
GNAZ	-4931
PRKAR2A	-4872
GNG11	-4806
PLCG2	-4748
ADCY3	-4480
ABI2	-4422
NOXA1	-4354
GSDMD	-4074
ARPC3	-3860
GNG7	-3737
IL6	-3644
IL18	-3577
GNAI3	-3336
CYFIP2	-3066
CRK	-2873
JUN	-2590
WIPF3	-2581
GNG10	-2266
PYCARD	-2170
ARPC2	-2036
DOCK1	-1837
GNB2	-1741
NFKB2	-1736
FGR	-1652
MAPK14	-1601
ENTPD1	-1568
ADCY1	-1452
WASF2	-1372
NCKAP1	-1320
RHBDF2	-1316
PRKAR2B	-1049
WASF3	-686
CYBA	-592
FYN	-487
ABI1	-466
WNT5A	-457
VAV1	-323
ACTR3	-130
FZD7	533
PSTPIP1	786
MYH9	883
APP	942
GNB4	1060
CASP1	1269
GNAI1	1426
WASF1	1436
TXNIP	2064
HSP90AB1	2253
AHCYL1	2482
ACTG1	2573
HCK	2605
PLK2	2880
DPEP2	3140
NFKB1	3151
GNG8	3224
GNB3	3259
GNAT3	3652
DVL2	3968
SUGT1	4549
SYK	4767
ADCY8	5094
ARPC5	5098
ARPC4	5323
ADCY5	5369
C3AR1	5455
MYO10	5616
IL1B	5632
CD247	5640
CD163	5706
MYH2	5841
ENTPD5	5898
GNG12	5942
ADCY2	5947
ACTB	6120
PTK2	6296
MAPK8	6356
PRKACB	6462
DPEP3	6636
GRB2	6943
NOXO1	7385
PRKACG	7445
NT5E	7525
IL1A	7925
PLCG1	8112
GNGT2	9612
GNGT1	9652
CD3G	9855

---

REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

	319
set	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI
setSize	18
pANOVA	0.00245
s.dist	-0.412
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FURIN	-11533
ATP2A3	-11251
LFNG	-11213
ST3GAL4	-11197
NOTCH1	-10959
ST3GAL6	-10924
B4GALT1	-10659
ATP2A1	-10383
TMED2	-5863
SEL1L	-4135
ATP2A2	-2675
NOTCH3	-2188
ST3GAL3	-1475
NOTCH2	-485
RAB6A	-286
NOTCH4	744
RFNG	816
MFNG	1617

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FURIN	-11533
ATP2A3	-11251
LFNG	-11213
ST3GAL4	-11197
NOTCH1	-10959
ST3GAL6	-10924
B4GALT1	-10659
ATP2A1	-10383
TMED2	-5863
SEL1L	-4135
ATP2A2	-2675
NOTCH3	-2188
ST3GAL3	-1475
NOTCH2	-485
RAB6A	-286
NOTCH4	744
RFNG	816
MFNG	1617

---

REACTOME_TBC_RABGAPS

REACTOME_TBC_RABGAPS

	1237
set	REACTOME_TBC_RABGAPS
setSize	40
pANOVA	0.00256
s.dist	-0.276
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TBC1D13	-11361
TBC1D24	-11131
TBC1D2	-10801
ULK1	-10702
TBC1D20	-10498
TBC1D10A	-10318
TSC2	-9932
TBC1D14	-9733
GGA1	-9302
RAB35	-9152
ARF6	-8794
RAB5C	-8174
RAB11B	-7842
RAB6B	-7399
RABGAP1	-6953
RABEP1	-6739
TBC1D16	-6085
TBC1D15	-6069
RAB4A	-5793
GGA2	-5735

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TBC1D13	-11361
TBC1D24	-11131
TBC1D2	-10801
ULK1	-10702
TBC1D20	-10498
TBC1D10A	-10318
TSC2	-9932
TBC1D14	-9733
GGA1	-9302
RAB35	-9152
ARF6	-8794
RAB5C	-8174
RAB11B	-7842
RAB6B	-7399
RABGAP1	-6953
RABEP1	-6739
TBC1D16	-6085
TBC1D15	-6069
RAB4A	-5793
GGA2	-5735
GGA3	-5371
RAB5B	-4193
RABGEF1	-3279
RAB8A	-2070
MAP1LC3B	-2004
RAB7A	-1836
TSC1	-1502
GABARAPL2	-1455
RAB33B	-1349
GABARAP	-1294
RAB11A	-847
TBC1D7	-442
RAB6A	-286
OPTN	913
TBC1D10B	1494
SYTL1	3666
TBC1D17	4983
RAB5A	5433
RAB8B	5905
TBC1D10C	9599

---

REACTOME_ESTROGEN_STIMULATED_SIGNALING_THROUGH_PRKCZ

REACTOME_ESTROGEN_STIMULATED_SIGNALING_THROUGH_PRKCZ

	1490
set	REACTOME_ESTROGEN_STIMULATED_SIGNALING_THROUGH_PRKCZ
setSize	6
pANOVA	0.00263
s.dist	-0.709
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
HRAS	-10751
PDPK1	-10204
NRAS	-9345
KRAS	-7903
PRKCZ	-7754
MAPK1	-7647

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
HRAS	-10751
PDPK1	-10204
NRAS	-9345
KRAS	-7903
PRKCZ	-7754
MAPK1	-7647

---

REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

	399
set	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS
setSize	83
pANOVA	0.00266
s.dist	-0.191
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
FCGR3A	-11998
NCKIPSD	-11007
MAPK3	-10990
PLD1	-10696
FCGR2A	-10113
CYFIP1	-10047
PLPP5	-9907
SRC	-9726
ARPC1B	-9607
ITPR3	-9355
PLD3	-9178
MYO9B	-9163
PLA2G6	-8669
PIK3R1	-8469
NCKAP1L	-8389
BAIAP2	-7933
PRKCD	-7879
BRK1	-7841
ITPR1	-7839
MAPK1	-7647

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
FCGR3A	-11998
NCKIPSD	-11007
MAPK3	-10990
PLD1	-10696
FCGR2A	-10113
CYFIP1	-10047
PLPP5	-9907
SRC	-9726
ARPC1B	-9607
ITPR3	-9355
PLD3	-9178
MYO9B	-9163
PLA2G6	-8669
PIK3R1	-8469
NCKAP1L	-8389
BAIAP2	-7933
PRKCD	-7879
BRK1	-7841
ITPR1	-7839
MAPK1	-7647
LYN	-7353
LIMK1	-7288
ARPC1A	-7219
CDC42	-7164
WASL	-6596
VAV3	-6523
PIK3R2	-6257
ELMO1	-6023
WIPF2	-5943
ITPR2	-5932
MYO5A	-5866
ACTR2	-5826
YES1	-5599
NCK1	-5559
RAC1	-5471
WIPF1	-5465
VAV2	-5410
MYO1C	-5402
ELMO2	-5259
ABL1	-5137
PLD2	-5090
PLCG2	-4748
ABI2	-4422
ARPC3	-3860
PLD4	-3831
NF2	-3770
PLPP4	-3582
PRKCE	-3273
PIK3CB	-3260
CYFIP2	-3066
CRK	-2873
WIPF3	-2581
ARPC2	-2036
DOCK1	-1837
FGR	-1652
WASF2	-1372
NCKAP1	-1320
WASF3	-686
FYN	-487
ABI1	-466
VAV1	-323
ACTR3	-130
HSP90AA1	563
MYH9	883
PAK1	1260
WASF1	1436
PIK3CA	2017
HSP90AB1	2253
AHCYL1	2482
ACTG1	2573
HCK	2605
SYK	4767
ARPC5	5098
ARPC4	5323
MYO10	5616
CD247	5640
MYH2	5841
ACTB	6120
PTK2	6296
GRB2	6943
PLCG1	8112
CFL1	8973
CD3G	9855

---

REACTOME_LINOLEIC_ACID_LA_METABOLISM

REACTOME_LINOLEIC_ACID_LA_METABOLISM

	409
set	REACTOME_LINOLEIC_ACID_LA_METABOLISM
setSize	7
pANOVA	0.00275
s.dist	-0.654
p.adjustANOVA	0.156

Top enriched genes

Top 20 genes

GeneID	Gene Rank
ELOVL3	-11539
FADS1	-10179
ELOVL5	-8758
ELOVL1	-8416
ELOVL2	-7442
FADS2	-7026
ACSL1	-4910

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
ELOVL3	-11539
FADS1	-10179
ELOVL5	-8758
ELOVL1	-8416
ELOVL2	-7442
FADS2	-7026
ACSL1	-4910

---

REACTOME_DEVELOPMENTAL_BIOLOGY

REACTOME_DEVELOPMENTAL_BIOLOGY

	76
set	REACTOME_DEVELOPMENTAL_BIOLOGY
setSize	1115
pANOVA	0.00296
s.dist	0.0527
p.adjustANOVA	0.162

Top enriched genes

Top 20 genes

GeneID	Gene Rank
KRTAP3-3	9853.0
KRTAP4-7	9828.0
LCE2D	9810.0
KRTAP4-6	9792.0
LCE3D	9787.0
KRTAP2-3	9756.0
KRTAP9-9	9751.0
KRTAP22-1	9690.0
KRTAP12-1	9671.0
KRTAP5-11	9669.0
KRT23	9635.0
H2AC18	9604.5
H2AC19	9604.5
LCE2C	9555.0
H2AC14	9533.0
KRTAP9-4	9517.0
SPRR3	9509.0
KRTAP19-3	9464.0
KRTAP6-2	9458.0
KRTAP5-10	9420.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
KRTAP3-3	9853.0
KRTAP4-7	9828.0
LCE2D	9810.0
KRTAP4-6	9792.0
LCE3D	9787.0
KRTAP2-3	9756.0
KRTAP9-9	9751.0
KRTAP22-1	9690.0
KRTAP12-1	9671.0
KRTAP5-11	9669.0
KRT23	9635.0
H2AC18	9604.5
H2AC19	9604.5
LCE2C	9555.0
H2AC14	9533.0
KRTAP9-4	9517.0
SPRR3	9509.0
KRTAP19-3	9464.0
KRTAP6-2	9458.0
KRTAP5-10	9420.0
DSC1	9388.0
KRTAP1-4	9380.0
KRTAP4-4	9358.0
IVL	9305.0
KRTAP9-3	9281.0
MED11	9273.0
KRTAP10-5	9250.0
KRTAP19-1	9217.0
LCE4A	9194.0
KRTAP25-1	9167.0
LELP1	9165.0
DSG1	9164.0
KRT6C	9161.0
MYF5	9131.0
RRAS	9124.0
KRTAP21-3	9120.0
KRT76	9109.0
DPPA4	9100.0
DSG4	9070.0
KRTAP4-5	9028.0
RPTN	9018.0
KRTAP5-7	8984.0
H4C12	8975.0
CFL1	8973.0
KRTAP4-8	8972.0
KRT14	8961.0
LCE1E	8959.0
KRTAP1-3	8953.0
KRTAP4-11	8948.0
KRTAP2-2	8944.0
SPINK5	8925.0
LEF1	8915.0
LCE6A	8910.0
KRTAP19-7	8857.0
KRT40	8851.0
WNT1	8839.0
RPL29	8825.0
FLRT3	8740.0
KRTAP12-4	8705.0
KRTAP1-5	8659.0
LGI4	8655.0
RPL39L	8650.0
EFNA4	8629.0
HNF4G	8617.0
CAP2	8610.0
SPRR2A	8605.0
SPRR2G	8604.0
RPL38	8599.0
H4C9	8578.0
H2BC14	8529.0
KRTAP12-3	8489.0
PTPRC	8483.0
KRTAP5-4	8480.0
KRT33A	8459.0
NODAL	8443.0
H2BC9	8440.5
H3C7	8440.5
LCE1C	8396.0
SCN11A	8385.0
KRT9	8384.0
KRT37	8352.0
MMP9	8323.0
KRTAP20-1	8308.0
SCN2A	8302.0
KRT35	8285.0
KRT15	8274.0
PSMB3	8251.0
UBB	8218.0
RPS18	8202.0
DMRT1	8188.0
PSMC2	8147.0
PSMB5	8115.0
PLCG1	8112.0
KRTAP13-3	8073.0
PKP1	8071.0
H4C4	8046.0
KRTAP10-3	8016.0
KRT4	7998.0
LCE5A	7984.0
ZNF335	7941.0
H4C16	7938.0
LIPK	7884.0
VLDLR	7869.0
KRTAP9-2	7799.0
MED4	7772.0
KRTAP2-1	7737.0
EFNB3	7728.0
H4C6	7701.0
LCE1A	7697.0
H4C11	7668.0
RPL27	7657.0
PAX4	7651.0
LGI2	7631.0
MYL12A	7590.0
CNTN2	7539.0
NCAN	7534.0
H4C1	7519.0
RPL7A	7517.0
KRTAP10-1	7499.0
CASP14	7494.0
MAPK12	7473.0
POLR2E	7449.0
PRKACG	7445.0
UBC	7391.0
KLK12	7384.0
H2BC6	7354.0
EOMES	7345.0
LCE2A	7338.0
TUBB4B	7335.0
KRTAP6-3	7319.0
KIF4B	7316.0
PSME2	7312.0
COL6A5	7304.0
MYF6	7287.0
CLDN7	7286.0
RPLP1	7277.0
KRT75	7252.0
RPS8	7241.0
MEF2A	7210.0
NTN1	7190.0
POLR2I	7160.0
KRTAP21-2	7159.0
RPS28	7157.0
FOXA3	7154.0
E2F1	7116.0
KRTAP9-6	7059.0
ARTN	7054.0
CDSN	7028.0
UBA52	7023.0
RPL36	7013.0
RPS9	7010.0
ENAH	7000.0
TUBB2B	6990.0
EFNA2	6987.0
GRB2	6943.0
ABLIM3	6902.0
ACVR1C	6899.0
PSMA4	6896.0
RHOC	6854.0
MED15	6831.0
H2BC17	6788.0
KRT19	6770.0
PLIN1	6734.0
INS	6732.0
CXCR4	6711.0
CDON	6707.0
PSEN1	6700.0
DAND5	6699.0
CD72	6690.0
NEUROG3	6670.0
NRCAM	6666.0
SCN3A	6640.0
KRT86	6616.0
RPL37	6552.0
RPL19	6543.0
SDC2	6516.0
LAMC1	6515.0
AP2S1	6513.0
PAGR1	6507.0
KRTAP6-1	6504.0
SPRR2E	6467.0
PRKACB	6462.0
RPL23A	6452.0
KMT2A	6412.0
KRT38	6392.0
FLG	6382.0
FGF2	6378.0
TEAD1	6362.0
MAPK8	6356.0
LCE3B	6339.0
RPL26L1	6328.0
TBPL2	6305.0
PSENEN	6297.0
PTK2	6296.0
WNT3A	6270.0
MED29	6254.0
KRTAP21-1	6245.0
NELL2	6220.0
KRT39	6214.0
RPS27A	6202.0
CER1	6157.0
NRP2	6126.0
ACTB	6120.0
ABLIM1	6082.0
KRTAP10-10	6059.0
DSP	6013.0
PIK3CD	6010.0
SCN1A	6002.0
EBF1	5985.0
RPL36AL	5928.5
NFASC	5911.0
KRTAP19-8	5907.0
EFNA5	5903.0
CDK8	5803.0
COL9A3	5801.0
SRGAP3	5800.0
TCF7	5784.0
KRTAP5-3	5768.0
TREM2	5764.0
POLR2C	5752.0
DAB1	5745.0
SCN2B	5724.0
CTCF	5696.0
ST8SIA2	5694.0
SPTBN2	5686.0
LGI1	5667.0
KCNQ3	5634.0
SHC1	5628.0
MYO10	5616.0
SPRR2F	5606.0
PSMB1	5600.0
MAFA	5595.0
DSCAM	5589.0
ONECUT3	5554.0
COL5A2	5534.0
ONECUT1	5475.0
MYC	5438.0
SHTN1	5426.0
RBM8A	5351.0
MAPK13	5346.0
NEUROD1	5333.0
ARPC4	5323.0
RPL23	5312.0
RPL3	5298.0
KRTAP15-1	5251.0
STAT3	5246.0
MAML2	5236.0
MED28	5231.0
PAK6	5228.0
ADAM10	5192.0
RND1	5189.0
NTN4	5182.0
UPF3A	5180.0
ARPC5	5098.0
ADAM22	5095.0
KRTAP10-9	5083.0
HOXA3	5047.0
PSMA6	5015.0
CACNA1D	4950.0
RBBP5	4947.0
RPL18A	4925.0
SPRR1B	4916.0
EVL	4855.0
TRPC7	4840.0
SEMA3A	4830.0
HNF1B	4795.0
RPL27A	4774.0
CCNC	4769.0
DLL3	4766.0
TIAM1	4715.0
LHX2	4707.0
ELOC	4694.0
EPHA1	4676.0
GFI1	4663.0
PRSS8	4635.0
CDH15	4621.0
KALRN	4576.0
RPS15	4571.0
PSMB4	4570.0
COL6A2	4526.0
CCND3	4523.0
PSMA7	4493.0
WNT10B	4463.0
RARG	4459.0
MET	4434.0
COL2A1	4429.0
PSMB8	4390.0
PSMD7	4369.0
MED16	4350.0
LCE3E	4347.0
SCN7A	4342.0
H4C5	4340.0
SEMA6D	4330.0
KRT73	4327.0
INSM1	4326.0
PIK3R3	4324.0
GRB7	4264.0
PSMC6	4259.0
MED20	4245.0
FOXL2	4237.0
RPL22	4227.0
SCN9A	4195.0
ANGPTL4	4163.0
GFRA4	4155.0
TEAD4	4152.0
DSG2	4141.0
GCK	4136.0
PIAS2	4117.0
HOXD4	4051.0
EPHB1	4050.0
RPS10	4013.0
KLK5	4003.0
MED10	3991.0
CACNB4	3981.0
COL4A3	3975.0
H2BC3	3960.0
BOC	3948.0
TFDP2	3903.0
HOXC4	3898.0
KRT6B	3873.0
CD36	3843.0
DPYSL3	3830.0
COL6A6	3803.0
GSPT1	3800.0
RPS2	3798.0
KRT83	3792.0
GATA4	3779.0
KRT32	3760.0
PSMA2	3743.0
RPS7	3735.0
TRPC3	3732.0
PPARGC1A	3706.0
YAP1	3695.0
ANK1	3694.0
RPL32	3678.0
PSMC5	3651.0
KRT74	3646.0
PCSK6	3622.0
RFX6	3591.0
ST14	3570.0
PSMD3	3550.0
RARB	3531.0
TCHH	3514.0
CEBPD	3507.0
RPS14	3506.0
EPHB2	3488.0
CRMP1	3457.0
ITGB3	3419.0
KRT10	3394.0
MYL6	3386.0
DSCAML1	3343.0
ARHGEF12	3332.0
ETF1	3331.0
ST8SIA4	3299.0
PSMD14	3291.0
HOXB4	3281.0
MED30	3257.0
RPL12	3236.0
PFN1	3225.0
HES1	3212.0
COL3A1	3200.0
FAU	3180.0
RAP1GAP	3169.0
ARHGEF11	3152.0
NFKB1	3151.0
TUBB3	3143.0
CDK5	3090.0
LAMA1	3031.0
RPS27L	2977.0
COL6A3	2972.0
RHOB	2970.0
SLC2A2	2960.0
RPL41	2942.0
TRPC1	2941.0
KRTAP3-1	2939.0
PSME3	2934.0
TUBB4A	2909.0
ADAM23	2889.0
KRTAP4-2	2857.0
PCK1	2796.0
NCAM1	2779.0
RPL10A	2777.0
PRKCQ	2767.0
PLXNA4	2723.0
RPS13	2709.0
KRT16	2701.0
GAP43	2692.0
CDKN1A	2683.0
NCOA1	2647.0
RPL3L	2627.0
UPF2	2614.0
H3C4	2601.0
ACTG1	2573.0
USP33	2555.0
ROBO1	2525.0
GDF1	2504.0
NR2F2	2450.0
PKNOX1	2435.0
RNPS1	2434.0
SNW1	2410.0
SPTBN5	2404.0
RPLP0	2389.0
HOXD1	2369.0
COL4A4	2368.0
KAZN	2366.0
NAB2	2361.0
DPYSL5	2350.0
KRT2	2340.0
WWTR1	2282.0
HSP90AB1	2253.0
GPC1	2202.0
PRX	2148.0
KRT7	2132.0
NCOR1	2130.0
WT1	2128.0
SEMA5A	2121.0
MESP2	2118.0
KRT79	2114.0
PSMD11	2103.0
DOK6	2086.0
KRTAP13-2	2082.0
SCD5	2075.0
EPHA4	2066.0
DLG4	2057.0
FOXO3	2056.0
PAK5	2054.0
SCN3B	2019.0
PIK3CA	2017.0
AP2A1	1991.0
SALL4	1956.0
MEF2B	1948.0
ANK2	1944.0
COL4A1	1939.0
GRB10	1913.0
ADAM11	1910.0
H2AC7	1901.5
H2BC7	1901.5
CSNK2B	1887.0
CTNNA2	1864.0
GATA6	1807.0
TRIO	1806.0
KRT82	1785.0
TUBB8	1769.0
LCE1F	1720.0
RPL8	1716.0
SMARCD3	1713.0
MEF2D	1710.0
ZFPM2	1701.0
MSGN1	1698.0
EPAS1	1654.0
MED18	1647.0
MIXL1	1640.0
CACNG2	1628.0
DHH	1604.0
TUBA8	1565.0
KRTAP4-3	1540.0
LAMA2	1533.0
SCN5A	1522.0
PSMD12	1473.0
SDCBP	1468.0
HIF3A	1466.0
FRS2	1458.0
GSK3B	1421.0
VASP	1418.0
FOXH1	1349.0
PSEN2	1327.0
KRTAP20-2	1321.0
MYH10	1309.0
RPS19	1298.0
EPHA10	1293.0
TUBA1B	1291.0
NUMB	1276.0
SCN4B	1272.0
PAK1	1260.0
CNOT6	1256.0
GFRA2	1246.0
RPSA	1235.0
NGEF	1185.0
PLXNA2	1168.0
DCC	1164.0
RGMB	1159.0
H2AC4	1158.0
RPL9	1151.0
SPTA1	1100.0
ROBO3	1058.0
KRT78	1035.0
CEBPB	1018.0
TUBA4A	1016.0
H3-3B	1000.0
KRTAP19-4	981.0
SCN10A	924.0
KRT5	900.0
MYH9	883.0
MED13	879.0
RPS15A	864.0
UNC5D	859.0
PDX1	851.0
FOXO1	849.0
PKP2	847.0
RPS3A	844.0
RPL15	813.0
KRTAP4-1	785.0
ABL2	736.0
ALCAM	699.0
RPL37A	621.0
CXCL12	612.0
PPP3CB	607.0
SPTB	606.0
SLIT3	601.0
PSME1	574.0
HSP90AA1	563.0
PERP	556.0
H4C3	548.0
PPARG	544.0
CLTC	529.0
PSMC3	511.0
EFNA1	449.0
ARHGEF28	410.0
TUBB6	387.0
PSMD9	385.0
SHC3	374.0
RELN	356.0
ASH2L	345.0
NRP1	305.0
SLC2A4	303.0
POLR2H	252.0
RGMA	236.0
CTNNA1	230.0
PSMA1	206.0
FGF9	170.0
KRT71	169.0
CACNA1C	140.0
RPL13A	136.5
H4C8	118.0
RPS20	111.0
RPS3	103.0
KRT81	85.0
ACVR2B	80.0
SPTBN4	74.0
KRT27	69.0
MEF2C	62.0
GFRA3	51.0
PSMA8	45.0
KRTAP10-7	25.0
COL4A2	23.0
KRTAP29-1	-32.0
NOG	-41.0
TBXT	-43.0
PSMA3	-63.0
DSG3	-96.0
RBBP4	-119.0
ACTR3	-130.0
KRTAP5-5	-169.0
RDX	-212.0
KRTAP13-1	-218.0
UTRN	-264.0
LEFTY2	-282.0
PSMC4	-326.0
RPS6	-330.0
RPL30	-338.0
MSI1	-450.0
SPRR2D	-453.0
FYN	-487.0
POLR2K	-528.0
PSMB6	-534.0
TRPC4	-540.0
RBPJ	-593.0
MED22	-622.0
DLL1	-631.0
RPL21	-645.0
CLTCL1	-661.0
H2BC4	-667.0
ARHGAP35	-669.0
SOS2	-671.0
NCOA6	-687.0
TUBA4B	-707.0
CACNA1I	-710.0
HSPA8	-751.0
EPHB6	-759.0
KRT34	-802.0
PAX6	-820.0
HMGCR	-848.0
GATA2	-849.0
EPHA3	-864.0
ITGA9	-865.0
RPL34	-917.0
KRTAP26-1	-939.0
RPL18	-941.0
DOK5	-947.0
COL5A3	-969.0
MAP2K1	-974.0
MYOD1	-995.0
SPAG9	-998.0
H3-3A	-1015.0
CACNG8	-1022.0
PCGF2	-1042.0
GAB2	-1066.0
OCLN	-1070.0
SPINK6	-1077.0
FABP4	-1123.0
PLXNC1	-1186.0
SPINK9	-1195.0
PSMD6	-1201.0
CDH1	-1241.0
NCK2	-1242.0
POLR2F	-1243.0
TBL1XR1	-1268.0
ITGA1	-1270.0
H3C2	-1296.0
HOXA1	-1298.0
PLXNB1	-1330.0
SEM1	-1346.0
SEMA4A	-1365.0
CACNB2	-1479.0
SNAI1	-1483.0
KRTAP5-8	-1489.0
PBX1	-1509.0
H4C2	-1542.0
RPL28	-1562.0
RPS6KA4	-1582.0
CHL1	-1588.0
EGFR	-1590.0
MAPK14	-1601.0
SPTBN1	-1621.0
TUBAL3	-1663.0
MED9	-1667.0
LHX9	-1717.0
EPHA6	-1718.0
GFRA1	-1740.0
AGAP2	-1773.0
PRKCA	-1822.0
DOCK1	-1837.0
STX1A	-1844.0
EED	-1848.0
TCF12	-1852.0
NCBP2	-1880.0
KRT84	-1909.0
APH1A	-1940.0
SCN8A	-1949.0
ADGRG6	-1982.0
RPL6	-1997.0
CDK4	-2008.0
ARPC2	-2036.0
IL6R	-2042.0
H2AJ	-2052.0
NCOA2	-2061.0
FOXP1	-2083.0
ITSN1	-2089.0
AP2B1	-2137.0
KAT2A	-2185.0
ADGRV1	-2195.0
KLK13	-2196.0
TSC22D1	-2236.0
PSMA5	-2270.0
AGRN	-2272.0
TUBA1A	-2281.0
ANK3	-2306.0
KRT1	-2327.0
CACNA1H	-2332.0
RPS16	-2334.0
RPL14	-2369.0
KRTAP5-6	-2372.0
CHD9	-2377.0
PSMB11	-2381.0
RARA	-2388.0
RPS5	-2393.0
HDAC2	-2399.0
PFN2	-2427.0
ROCK2	-2459.0
NOTO	-2514.0
AKT3	-2517.0
SHH	-2520.0
CACNA1S	-2528.0
MYL12B	-2538.0
H3C1	-2553.0
RBX1	-2572.0
CNTNAP1	-2582.0
JUN	-2590.0
H3C6	-2591.0
RPS6KA2	-2625.0
SLIT1	-2626.0
SH3GL2	-2631.0
KRTAP10-4	-2638.0
H2AC20	-2661.0
RPL17	-2701.0
HJV	-2702.0
CTNNB1	-2706.0
RPL35A	-2718.0
NR5A2	-2741.0
COL9A1	-2743.0
CUL2	-2866.0
RPL13	-2882.0
RPL11	-2943.0
BNIP2	-2986.0
KRTAP19-6	-2991.0
ARHGAP39	-2999.0
SRGAP1	-3018.0
GAB1	-3022.0
SEMA3E	-3051.0
ITGAV	-3056.0
RUNX1	-3102.0
KCNQ2	-3130.0
HOXA4	-3164.0
DNM1	-3177.0
RPL7	-3189.0
H2BC12	-3226.0
KRT3	-3230.0
RASA1	-3259.0
PIK3CB	-3260.0
H2BC5	-3284.0
KRTAP5-9	-3365.0
TGS1	-3371.0
SUZ12	-3439.0
CNOT9	-3575.0
CACNA1G	-3576.0
LHX3	-3596.0
CDH2	-3603.0
TCF4	-3618.0
TUBB2A	-3682.0
EP300	-3709.0
PSMB9	-3711.0
IHH	-3715.0
HNF4A	-3723.0
MED6	-3752.0
LCE1B	-3754.0
NR5A1	-3765.0
PSMB10	-3782.0
PSMF1	-3800.0
SEMA4D	-3817.0
COL5A1	-3838.0
LIN28A	-3852.0
ARPC3	-3860.0
KRTAP8-1	-3867.0
CASC3	-3868.0
SEMA7A	-3874.0
MED21	-3892.0
LDB1	-3900.0
MAP2K6	-3941.0
MED24	-3953.0
CAP1	-3968.0
GRIN2B	-3971.0
KRT28	-3998.0
UNC5B	-3999.0
PSMC1	-4003.0
HOXB3	-4011.0
DNM3	-4015.0
GDNF	-4044.0
RPS12	-4089.0
SOX2	-4100.0
KRT20	-4101.0
LAMB1	-4152.0
CYP51A1	-4187.0
TEAD2	-4190.0
ABLIM2	-4214.0
MAFB	-4221.0
SEMA6A	-4223.0
KRTAP10-6	-4233.0
CDK19	-4242.0
RPL4	-4255.0
MED19	-4280.0
EPHA2	-4298.0
RPS26	-4301.0
EZH2	-4305.0
LIPN	-4310.0
NCOA3	-4313.0
GRIN1	-4321.0
PSMD1	-4322.0
NR6A1	-4330.0
PSMD4	-4377.0
KRTAP24-1	-4380.0
MMP2	-4390.0
KRT72	-4429.0
NCBP1	-4432.0
FAM120B	-4457.0
PSMD5	-4468.0
DOK1	-4481.0
PSMB2	-4485.0
PABPC1	-4487.0
NAB1	-4489.0
DPYSL2	-4512.0
ISL1	-4568.0
NANOG	-4583.0
FOXA1	-4586.0
PTPN11	-4589.0
RPL35	-4617.0
PMP22	-4625.0
RPL26	-4649.0
UNC5A	-4683.0
H3C10	-4692.0
HOXD3	-4706.0
H2AX	-4784.0
MAML3	-4814.0
SPTAN1	-4822.0
PRKAR2A	-4872.0
SOX9	-4904.0
RPS11	-4948.0
SLIT2	-4960.0
MED13L	-4962.0
PI3	-4967.0
RPS24	-5018.0
TNF	-5068.0
MED23	-5081.0
ARHGEF7	-5104.0
SMAD3	-5128.0
ABL1	-5137.0
EGR2	-5145.0
PSMD13	-5161.0
ERBB2	-5169.0
EZR	-5179.0
CNTN1	-5225.0
DLG1	-5243.0
MYL9	-5269.0
CDH4	-5293.0
AJUBA	-5296.0
CEBPA	-5311.0
CSNK2A1	-5317.0
MAPK11	-5323.0
PTF1A	-5361.0
PLXNA1	-5378.0
VAV2	-5410.0
LEP	-5432.0
NEO1	-5436.0
ITGA5	-5452.0
RAC1	-5471.0
PKP4	-5476.0
EIF4G1	-5509.0
KRTAP27-1	-5518.0
LCE2B	-5524.0
HELZ2	-5553.0
NCK1	-5559.0
YES1	-5599.0
DRAP1	-5619.0
DOK4	-5621.0
PSPN	-5668.0
H3C11	-5690.0
BMP4	-5721.0
MAGOH	-5745.0
PAK2	-5763.0
SMAD4	-5774.0
ACVR2A	-5811.0
ACTR2	-5826.0
ROBO2	-5827.0
AKAP5	-5840.0
PRDM14	-5845.0
SCN1B	-5938.0
SALL1	-5940.0
ELOB	-5946.0
H4C13	-5978.0
NTN3	-5993.0
KMT2C	-6024.0
LGI3	-6040.0
KRTAP23-1	-6048.0
H2AC6	-6049.0
H2BC21	-6060.0
MAPK7	-6156.0
RPL31	-6186.0
TRIM33	-6206.0
H2AZ1	-6211.0
SOS1	-6228.0
SMAD2	-6230.0
RPS29	-6253.0
PIK3R2	-6257.0
DPYSL4	-6292.0
LHX4	-6320.0
POLR2B	-6330.0
IRS2	-6334.0
KRT77	-6341.0
ITGA2	-6359.0
HDAC3	-6372.0
JUP	-6376.0
PML	-6388.0
DOK2	-6430.0
WNT4	-6435.0
KRTAP10-11	-6442.0
MED17	-6473.0
FOXD3	-6500.0
SPRR1A	-6506.0
VAV3	-6523.0
CAPN1	-6557.0
TAL1	-6576.0
KLF4	-6582.0
WASL	-6596.0
PSME4	-6624.0
PLXND1	-6625.0
SIAH1	-6647.0
CLASP2	-6653.0
NRTN	-6682.0
UNC5C	-6712.0
CREB1	-6716.0
POLR2D	-6736.0
EFNA3	-6748.0
SOX10	-6749.0
H2AC8	-6751.0
MYH11	-6762.0
RPS25	-6807.0
EPHA8	-6882.0
CBFB	-6906.0
CDK5R1	-6922.0
RPS23	-6932.0
RPLP2	-6976.0
H2BC10	-6977.0
MAG	-6989.0
ZNF638	-7027.0
MED1	-7048.0
TBX6	-7056.0
H2BC8	-7060.0
RET	-7096.0
H2BC11	-7099.0
KRTAP19-5	-7106.0
AP2M1	-7112.0
MAGOHB	-7130.0
POU5F1	-7140.0
CDC42	-7164.0
ARPC1A	-7219.0
H2BC15	-7227.0
FLI1	-7270.0
PTPRA	-7287.0
LIMK1	-7288.0
RPL24	-7327.0
SIAH2	-7346.0
LYN	-7353.0
SCN4A	-7372.0
FOXF1	-7405.0
MED27	-7424.0
FOXA2	-7426.0
MED31	-7479.0
KRT24	-7484.0
LIPM	-7485.0
CAPNS1	-7520.0
CACNG3	-7526.0
EIF4A3	-7578.0
MYH14	-7587.0
MAPK1	-7647.0
KRTAP13-4	-7651.0
KRTAP11-1	-7785.0
CNTN6	-7788.0
ITGA2B	-7827.0
PSMD8	-7863.0
APH1B	-7881.0
KRAS	-7903.0
ZNF467	-7911.0
KRT80	-7979.0
THRAP3	-7980.0
EPHA5	-8050.0
PRNP	-8062.0
NKX2-2	-8103.0
PIP5K1C	-8119.0
LIPJ	-8149.0
PSMB7	-8167.0
CACNG4	-8177.0
ROCK1	-8181.0
KLF5	-8209.0
LPL	-8225.0
CDK2	-8236.0
CDX2	-8241.0
POLR2A	-8309.0
CELA2A	-8318.0
HHEX	-8345.0
MYB	-8346.0
POLR2L	-8369.0
MED7	-8384.0
KRTAP10-12	-8414.0
EPHB3	-8436.0
PAK4	-8450.0
RANBP9	-8460.0
PIK3R1	-8469.0
STX1B	-8506.0
GSC	-8538.0
KRT18	-8633.0
DSC2	-8635.0
EPHA7	-8654.0
ITGA10	-8656.0
DAG1	-8663.0
MED8	-8677.0
NCSTN	-8683.0
POLR2J	-8695.0
TGM5	-8709.0
TGFB1	-8731.0
POU3F1	-8770.0
KLK8	-8791.0
FARP2	-8827.0
MYOG	-8850.0
KRT85	-8858.0
CACNB3	-8891.0
PITPNA	-8910.0
EPHB4	-8933.0
RPS21	-8944.0
RPS27	-8947.0
H2BC13	-8955.0
TUBA3E	-8966.0
KRT13	-8991.0
CLASP1	-9015.0
CLTB	-9039.0
ITGB1	-9073.0
RPS6KA5	-9125.0
KRTAP10-8	-9130.0
TLN1	-9145.0
CLTA	-9154.0
MYO9B	-9163.0
TRPC6	-9198.0
FES	-9202.0
TUBA1C	-9236.0
H2BC1	-9258.0
PKP3	-9260.0
RELA	-9312.0
DKK1	-9337.0
H3C3	-9339.0
NRAS	-9345.0
NKX6-1	-9370.0
PAXIP1	-9371.0
FGFR1	-9383.0
EFNB2	-9412.0
KRT31	-9436.0
MED26	-9449.0
CSNK2A2	-9451.0
KRTAP16-1	-9460.0
H3C8	-9465.0
MEIS1	-9512.0
EVPL	-9533.0
KRT6A	-9538.0
PPARA	-9572.0
ARPC1B	-9607.0
SMARCA4	-9645.0
ACVR1B	-9660.0
MED25	-9704.0
SRC	-9726.0
TUBB1	-9731.0
CREBBP	-9764.0
KRTAP2-4	-9765.0
ADIPOQ	-9768.0
MPZ	-9773.0
TUBA3C	-9788.0
AMH	-9862.0
PRKACA	-9870.0
FGF10	-9871.0
KRTAP5-2	-9886.0
SPI1	-9909.0
KLK14	-9911.0
GIT1	-9920.0
H2AZ2	-9922.0
DSC3	-9944.0
COL6A1	-9964.0
HOXB1	-9966.0
KRT36	-10001.0
PKLR	-10034.0
PSMD2	-10038.0
KAT2B	-10050.0
POU3F2	-10058.0
HOXB2	-10075.0
POLR2G	-10081.0
KRTAP3-2	-10088.0
CACNB1	-10116.0
RPL22L1	-10140.0
SREBF2	-10197.0
RXRA	-10375.0
RPL5	-10388.0
AP2A2	-10414.0
SRGAP2	-10441.0
KRTAP19-2	-10453.0
COL9A2	-10457.0
DNM2	-10470.0
PDLIM7	-10539.0
AKT2	-10544.0
KRT12	-10567.0
KRTAP5-1	-10585.0
TFDP1	-10617.0
RPS6KA1	-10646.0
KRT26	-10650.0
ZSCAN10	-10681.0
DEK	-10685.0
NCOR2	-10707.0
KRTAP9-1	-10721.0
HRAS	-10751.0
HOXA2	-10775.0
AKT1	-10886.0
CSTA	-10905.0
ZSWIM8	-10914.0
CARM1	-10948.0
NOTCH1	-10959.0
RHOA	-10972.0
MBP	-10974.0
PPL	-10978.0
MAPK3	-10990.0
KRT33B	-11005.0
MAP2K2	-11023.0
LYPLA2	-11091.0
LIMK2	-11100.0
CSF3R	-11123.0
WDR5	-11145.0
PTGDS	-11163.0
MAML1	-11172.0
H3C12	-11204.0
KRT8	-11273.0
LEFTY1	-11278.0
SREBF1	-11280.0
HNF1A	-11341.0
ADIRF	-11378.0
KRTAP17-1	-11386.0
YY1	-11411.0
KRT17	-11412.0
TCF3	-11420.0
KRTAP1-1	-11448.0
IAPP	-11472.0
FURIN	-11533.0
H2BC26	-11565.0
LCE3A	-11590.0
TGM1	-11599.0
RPL10L	-11704.0
TYROBP	-11723.0
KRT25	-11842.0
KMT2D	-11849.0
CEBPE	-11947.0
KRTAP12-2	-11949.0
KRTAP10-2	-12006.0
TUBA3D	-12026.0

---

REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES

REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES

	622
set	REACTOME_IRE1ALPHA_ACTIVATES_CHAPERONES
setSize	48
pANOVA	0.00316
s.dist	-0.246
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLA2G4B	-11895
XBP1	-11275
DNAJC3	-11234
HYOU1	-11075
ATP6V0D1	-11015
PREB	-10446
KLHDC3	-10317
SSR1	-10286
EXTL3	-10224
GOSR2	-10162
ERN1	-9956
ZBTB17	-9908
CUL7	-9850
TLN1	-9145
EXTL1	-9037
SEC31A	-8587
MYDGF	-8579
YIF1A	-8567
DNAJB9	-7756
ARFGAP1	-7715

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLA2G4B	-11895
XBP1	-11275
DNAJC3	-11234
HYOU1	-11075
ATP6V0D1	-11015
PREB	-10446
KLHDC3	-10317
SSR1	-10286
EXTL3	-10224
GOSR2	-10162
ERN1	-9956
ZBTB17	-9908
CUL7	-9850
TLN1	-9145
EXTL1	-9037
SEC31A	-8587
MYDGF	-8579
YIF1A	-8567
DNAJB9	-7756
ARFGAP1	-7715
ADD1	-6921
WIPI1	-6765
PDIA5	-6643
CXXC1	-6474
WFS1	-6273
SRPRA	-5887
DNAJB11	-3987
EXTL2	-3905
SYVN1	-3216
LMNA	-3017
DCTN1	60
ACADVL	212
PDIA6	538
GFPT1	756
EDEM1	890
CTDSP2	1989
SERP1	2297
HSPA5	2317
HDGF	2894
PPP2R5B	3187
SRPRB	3458
DDX11	5250
SHC1	5628
TATDN2	5789
TPP1	6509
FKBP14	7374
GSK3A	8002
KDELR3	8719

---

REACTOME_VESICLE_MEDIATED_TRANSPORT

REACTOME_VESICLE_MEDIATED_TRANSPORT

	934
set	REACTOME_VESICLE_MEDIATED_TRANSPORT
setSize	642
pANOVA	0.00317
s.dist	-0.0682
p.adjustANOVA	0.163

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	-12026
SLC2A8	-11757
TOR1A	-11702
CHMP4A	-11522
PACSIN2	-11499
GRK2	-11491
ARF1	-11363
TBC1D13	-11361
HP	-11347
SURF4	-11331
HPS1	-11320
RIN1	-11282
AGPAT3	-11261
TBC1D24	-11131
ASPSCR1	-11094
HPS4	-11090
YWHAB	-11084
ARFRP1	-11080
HYOU1	-11075
BIN1	-11025

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	-12026
SLC2A8	-11757
TOR1A	-11702
CHMP4A	-11522
PACSIN2	-11499
GRK2	-11491
ARF1	-11363
TBC1D13	-11361
HP	-11347
SURF4	-11331
HPS1	-11320
RIN1	-11282
AGPAT3	-11261
TBC1D24	-11131
ASPSCR1	-11094
HPS4	-11090
YWHAB	-11084
ARFRP1	-11080
HYOU1	-11075
BIN1	-11025
PPP6R3	-11022
CTSZ	-10925
AKT1	-10886
TBC1D2	-10801
AP1M1	-10791
CSNK1D	-10770
ULK1	-10702
DENND4B	-10655
SYNJ2	-10589
HGS	-10582
TRAPPC10	-10547
AKT2	-10544
KIFC2	-10529
RACGAP1	-10526
TBC1D20	-10498
DNM2	-10470
EPN1	-10465
DENND3	-10462
PREB	-10446
AP2A2	-10414
CD4	-10366
KIF2B	-10339
MARCO	-10326
TBC1D10A	-10318
GJB3	-10306
RAB32	-10171
GOSR2	-10162
SBF1	-10143
TRAPPC2L	-10112
BLOC1S1	-10095
COPS5	-10067
DYNC1LI2	-10030
ARRB1	-10007
KIF5A	-10003
TSC2	-9932
RAB38	-9888
STX5	-9876
GALNT1	-9831
TUBA3C	-9788
TBC1D14	-9733
TUBB1	-9731
SRC	-9726
AREG	-9604
GAK	-9589
GJC2	-9514
VPS51	-9513
VPS4A	-9485
CHMP2A	-9473
SCARB1	-9444
STAB1	-9439
SEC16A	-9376
DYNLL2	-9313
GGA1	-9302
VPS37B	-9256
AGFG1	-9249
TUBA1C	-9236
TGFA	-9233
AP1G2	-9166
CLTA	-9154
RAB35	-9152
GJB4	-9115
EXOC7	-9074
CLTB	-9039
TUBA3E	-8966
MON1B	-8900
LMAN1L	-8877
AVP	-8823
YWHAQ	-8800
ARF6	-8794
SERPINA1	-8752
GPS1	-8747
IGF2R	-8732
KIF1C	-8690
PLA2G6	-8669
PRKAB1	-8651
SEC31A	-8587
ARF3	-8585
EXOC8	-8501
KIF3C	-8474
ARFGAP2	-8462
ANKRD27	-8457
AP4M1	-8455
CD59	-8454
VPS25	-8439
LMAN2	-8427
COLEC12	-8329
CUX1	-8315
DCTN2	-8285
TMED10	-8244
SNX18	-8213
KIFC1	-8212
CLINT1	-8202
RAB5C	-8174
BICD2	-8144
EREG	-8140
SYT8	-8135
RIN3	-8121
PIP5K1C	-8119
RIC1	-8052
RAB27A	-7978
STAM2	-7929
YWHAE	-7851
RAB11B	-7842
DYNC1H1	-7804
HBB	-7751
TPD52	-7745
PRKAG2	-7718
ARFGAP1	-7715
TRAPPC12	-7709
GBF1	-7657
COG4	-7656
FNBP1	-7625
DCTN4	-7465
RAB6B	-7399
APOL1	-7394
DTNBP1	-7360
VPS37C	-7326
PAFAH1B2	-7323
AP1B1	-7321
KIF12	-7318
NSF	-7297
TXNDC5	-7289
VPS52	-7223
ARPC1A	-7219
AP3B1	-7204
KLC1	-7189
TFRC	-7152
ARRB2	-7141
AP2M1	-7112
CHMP4C	-7109
MADD	-7059
PACSIN3	-7043
SNAP91	-7022
GORASP1	-6962
RABGAP1	-6953
USE1	-6880
GOLGB1	-6873
GOLGA2	-6845
TRAPPC13	-6806
SCARF1	-6758
RABEP1	-6739
EXOC2	-6721
STON1	-6704
LRP1	-6665
COPA	-6640
WASL	-6596
ARFGAP3	-6592
TRIP10	-6543
COG3	-6530
TRAPPC9	-6509
KLC4	-6508
NAPG	-6394
SH3GL1	-6377
CALM1	-6248
HIP1R	-6184
KIF13B	-6162
CHRM2	-6157
COPS7B	-6154
KLC2	-6153
EXOC6	-6096
TBC1D16	-6085
TBC1D15	-6069
TMED3	-6010
GOLGA1	-5941
RAB18	-5919
KIF2C	-5909
CHMP2B	-5904
ANKRD28	-5892
SYT2	-5890
SNF8	-5874
MYO5A	-5866
TMED2	-5863
ACTR2	-5826
DAB2	-5814
RAB4A	-5793
MVB12B	-5780
DENND1C	-5772
HSPH1	-5761
GGA2	-5735
HBEGF	-5706
TBC1D1	-5667
HIP1	-5638
VTI1A	-5634
ACTR1A	-5584
COPS7A	-5567
KIF22	-5561
RHOBTB3	-5520
RAC1	-5471
MYO1C	-5402
COPE	-5379
GGA3	-5371
HPR	-5370
DNAJC6	-5344
RAB36	-5341
COPS6	-5338
CBL	-5273
VPS53	-5266
CYTH1	-5255
KIF2A	-5206
GALNT2	-5200
EPN2	-5166
SEC24B	-5148
COPZ1	-5093
TRAPPC6B	-5062
SNAP29	-5043
LMAN1	-5039
DENND1B	-5024
TSG101	-4903
RAB14	-4878
DENND6A	-4825
SPTAN1	-4822
DENND5A	-4768
CNIH3	-4703
KIF1A	-4665
DENND1A	-4655
MAN2A1	-4502
AP4E1	-4417
VPS28	-4397
RALGAPA2	-4396
SFN	-4372
MVB12A	-4286
KIF3B	-4282
TRAPPC1	-4197
RAB5B	-4193
COPS3	-4178
GOLGA5	-4150
SEC24C	-4094
VPS37D	-4048
VAMP8	-4047
TMED9	-4026
DNM3	-4015
GJB7	-4004
ACBD3	-3966
TOR1B	-3921
TRAPPC3	-3911
KDELR2	-3890
ARPC3	-3860
SPARC	-3858
BLOC1S6	-3827
TRAPPC4	-3732
TUBB2A	-3682
DYNC1LI1	-3617
KIF20A	-3509
EPS15L1	-3473
RALA	-3346
COPB2	-3316
CPD	-3312
CHMP3	-3295
COPG1	-3289
RABGEF1	-3279
REPS1	-3271
SEC23IP	-3247
TRAPPC6A	-3225
DENND4C	-3218
DNM1	-3177
CAPZA2	-3154
COPS4	-3148
YWHAG	-3140
SEC22A	-3132
CNIH1	-3109
CLVS2	-3101
RAB10	-3046
GJD2	-2967
KIF16B	-2947
GCC2	-2928
AP1S1	-2838
PLIN3	-2830
CHMP6	-2715
YWHAH	-2710
GJB6	-2695
STX18	-2650
COG1	-2647
SH3GL2	-2631
AKT3	-2517
TMF1	-2510
AP1S3	-2481
CHMP4B	-2443
COPS8	-2428
BNIP1	-2426
LDLRAP1	-2324
ANK3	-2306
TUBA1A	-2281
VAMP3	-2222
GOLGA4	-2165
VPS36	-2164
AP2B1	-2137
SEC24D	-2117
ITSN1	-2089
FOLR1	-2084
RAB8A	-2070
ARPC2	-2036
STON2	-2017
MAP1LC3B	-2004
ITSN2	-1986
TJP1	-1974
EXOC4	-1961
GOSR1	-1952
ARCN1	-1947
NAA30	-1892
FZD4	-1854
RAB7A	-1836
KIF9	-1814
DENND6B	-1801
EXOC3	-1786
NAA35	-1669
TUBAL3	-1663
COG7	-1639
SPTBN1	-1621
EGFR	-1590
BET1L	-1567
STAM	-1561
COPG2	-1557
SYT11	-1525
TSC1	-1502
STX17	-1492
MAN2A2	-1488
KIF1B	-1478
RAB27B	-1477
GABARAPL2	-1455
ARF5	-1444
GJB2	-1375
FCHO1	-1356
RAB33B	-1349
LMAN2L	-1345
TRAPPC8	-1336
VPS54	-1322
SCARB2	-1306
GABARAP	-1294
KIF20B	-1285
MIA2	-1228
MAN1A2	-1170
SSC5D	-1165
MIA3	-1128
SAA1	-1095
LDLR	-1067
APOA1	-1006
AP4B1	-945
USP6NL	-944
COL1A1	-923
AAK1	-922
FCHO2	-916
RAB3A	-912
NECAP2	-886
RAB11A	-847
SNX2	-788
KIF21B	-758
HSPA8	-751
STX6	-725
TUBA4B	-707
CLTCL1	-661
CYTH3	-629
CALR	-616
SCARA5	-549
SBF2	-536
EPGN	-505
WNT5A	-457
TBC1D7	-442
DYNC1I2	-374
COG5	-300
TMEM115	-287
RAB6A	-286
COLEC11	-272
BLOC1S4	-206
SYNJ1	-178
KIF25	-167
YWHAZ	-146
PRKAG3	-137
ACTR3	-130
DENND2A	-110
RAB31	-104
ALS2	-102
KIF18B	-98
MSR1	-42
ARFIP2	0
COL4A2	23
DYNLL1	26
DCTN1	60
RGP1	64
SPTBN4	74
KIF5B	190
SYT9	198
GCC1	228
PPP6R1	248
SLC2A4	303
EXOC5	307
VPS4B	311
UBQLN1	328
KIF27	338
SEC22C	353
TUBB6	387
PRKAG1	401
KDELR1	413
STX4	432
BICD1	442
AGTR1	484
CLTC	529
CAPZA1	546
HSP90AA1	563
SPTB	606
SYS1	615
TACR1	692
PPP6C	723
ZW10	752
GRK3	757
RAB43	796
KIF26A	873
MYH9	883
RALGAPB	908
OPTN	913
COL7A1	936
APP	942
TUBA4A	1016
AP3S1	1051
SEC23A	1053
PUM1	1056
COG8	1061
GJD3	1096
SPTA1	1100
SNX9	1160
KIF23	1192
STX10	1254
TUBA1B	1291
DCTN3	1324
LNPEP	1375
DENND4A	1408
MON1A	1411
PICALM	1483
MAN1A1	1485
TBC1D10B	1494
CHMP7	1498
TUBA8	1565
KIF15	1595
KIAA0319	1674
CNIH2	1707
TUBB8	1769
TMED7	1779
NAPA	1853
RAB3GAP1	1867
COL4A1	1939
ANK2	1944
MCFD2	1949
AP2A1	1991
STX16	1994
DENND2C	2063
APOB	2093
ARL1	2107
COG2	2126
TRIP11	2181
PRKAA2	2223
PLA2G4A	2243
SLC18A3	2277
CYTH2	2346
HPX	2352
NBAS	2384
RAB1B	2396
SPTBN5	2404
USO1	2420
KIF19	2480
VTA1	2501
KIF26B	2502
KIF18A	2526
PAFAH1B1	2571
ACTG1	2573
COG6	2574
CTTN	2608
PIK3C2A	2634
SNX5	2664
C2CD5	2707
MYO6	2826
TUBB4A	2909
RINT1	2945
RHOQ	3006
GJA1	3042
TUBB3	3143
MAN1C1	3148
SH3GL3	3157
COL3A1	3200
GAPVD1	3219
SORT1	3232
RAB3IP	3308
VAMP4	3348
PAFAH1B3	3357
ALPP	3374
KIF11	3432
AMPH	3465
COL1A2	3519
SAR1B	3547
UBAP1	3559
TFG	3563
VPS37A	3587
NAPB	3648
SYTL1	3666
TRAPPC5	3682
ANK1	3694
APOE	3745
F5	3783
CHMP5	3826
CD36	3843
RIN2	3851
AP1G1	3910
DVL2	3968
GJD4	4007
GJC1	4014
EXOC1	4049
CAPZB	4075
SCFD1	4119
DENND5B	4139
KLC3	4184
EGF	4243
ALB	4370
DYNC1I1	4409
DNASE2	4457
RAB3GAP2	4503
ALS2CL	4513
ADRB2	4529
SGIP1	4532
TBC1D4	4543
RAB13	4624
SEC22B	4626
STXBP3	4656
FTL	4671
AP1M2	4681
DCTN5	4684
EPS15	4747
KIFAP3	4842
TBC1D17	4983
TRAPPC11	5030
ARPC5	5098
LRP2	5099
VPS45	5107
CTSC	5130
SCOC	5133
GJA3	5191
BET1	5206
ARPC4	5323
KIF3A	5389
TPD52L1	5404
RAB5A	5433
PRKAB2	5526
GNS	5528
SEC13	5529
AP4S1	5533
BLOC1S3	5584
DENND2B	5587
PACSIN1	5594
SYT1	5622
DCTN6	5635
SPTBN2	5686
CD163	5706
RABEPK	5852
NEDD8	5890
RAB8B	5905
CLVS1	5978
GOLIM4	6000
AMBP	6062
CYTH4	6072
ACTB	6120
NAA38	6132
SH3D19	6137
RPS27A	6202
VAMP2	6211
CD55	6247
DENND2D	6323
SNAPIN	6386
BTC	6417
TGOLN2	6423
AP2S1	6513
HSP90B1	6662
COPB1	6688
ACTR10	6689
INS	6732
KIF6	6733
GJA10	6828
SEC24A	6864
RAB30	6927
GRB2	6943
TUBB2B	6990
UBA52	7023
STAB2	7039
KIF4B	7316
TUBB4B	7335
CENPE	7359
RAB21	7366
RAB3IL1	7383
UBC	7391
COPS2	7523
ARF4	7562
NECAP1	7576
RAB1A	7620
SEC16B	7694
KIF21A	7816
RINL	7821
FTH1	7833
CFTR	7876
SNAP23	7885
FNBP1L	7920
TF	7948
UBB	8218
RAB12	8283
M6PR	8301
GDI2	8312
GJA8	8358
CAPZA3	8517
COPZ2	8567
JCHAIN	8651
GJA5	8674
KDELR3	8719
MASP1	8750
GJB5	8775
YKT6	8795
GJA9	8820
RAB39A	8923
GJA4	9056
GRIA1	9139
HBA2	9229
HBA1	9344
CHML	9497
SCGB3A2	9581
TBC1D10C	9599
IL7R	9617
CD3G	9855
CD3D	9867

---

REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

	200
set	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF
setSize	53
pANOVA	0.00341
s.dist	-0.233
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCAP	-11614
LSS	-11419
SREBF1	-11280
CARM1	-10948
RXRA	-10375
SREBF2	-10197
CREBBP	-9764
HMGCS1	-9702
MVD	-9581
PPARA	-9572
ACACB	-9522
FASN	-9192
SQLE	-9083
INSIG1	-8838
MBTPS1	-8808
MTF1	-8251
PMVK	-7938
MED1	-7048
GGPS1	-6842
INSIG2	-6245

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCAP	-11614
LSS	-11419
SREBF1	-11280
CARM1	-10948
RXRA	-10375
SREBF2	-10197
CREBBP	-9764
HMGCS1	-9702
MVD	-9581
PPARA	-9572
ACACB	-9522
FASN	-9192
SQLE	-9083
INSIG1	-8838
MBTPS1	-8808
MTF1	-8251
PMVK	-7938
MED1	-7048
GGPS1	-6842
INSIG2	-6245
ACACA	-6054
HELZ2	-5553
SEC24B	-5148
DHCR7	-4749
CYP51A1	-4187
SCD	-4167
SEC24C	-4094
TGS1	-3371
NFYA	-3268
CHD9	-2377
SEC24D	-2117
NCOA2	-2061
KPNB1	-1610
TBL1XR1	-1268
NFYC	-1144
MVK	-1076
FDPS	-955
HMGCR	-848
NCOA6	-687
FDFT1	-19
SEC23A	1053
NFYB	1122
SC5D	1224
SMARCD3	1713
TM7SF2	2578
NCOA1	2647
ELOVL6	3026
RAN	3537
SAR1B	3547
IDI1	4847
SP1	5167
SEC24A	6864
GPAM	8224

---

REACTOME_RAB_REGULATION_OF_TRAFFICKING

REACTOME_RAB_REGULATION_OF_TRAFFICKING

	1359
set	REACTOME_RAB_REGULATION_OF_TRAFFICKING
setSize	110
pANOVA	0.0035
s.dist	-0.161
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TBC1D13	-11361
HPS1	-11320
RIN1	-11282
TBC1D24	-11131
HPS4	-11090
AKT1	-10886
TBC1D2	-10801
ULK1	-10702
DENND4B	-10655
TRAPPC10	-10547
AKT2	-10544
TBC1D20	-10498
DENND3	-10462
TBC1D10A	-10318
RAB32	-10171
SBF1	-10143
TRAPPC2L	-10112
TSC2	-9932
RAB38	-9888
TBC1D14	-9733

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TBC1D13	-11361
HPS1	-11320
RIN1	-11282
TBC1D24	-11131
HPS4	-11090
AKT1	-10886
TBC1D2	-10801
ULK1	-10702
DENND4B	-10655
TRAPPC10	-10547
AKT2	-10544
TBC1D20	-10498
DENND3	-10462
TBC1D10A	-10318
RAB32	-10171
SBF1	-10143
TRAPPC2L	-10112
TSC2	-9932
RAB38	-9888
TBC1D14	-9733
GGA1	-9302
RAB35	-9152
MON1B	-8900
ARF6	-8794
ANKRD27	-8457
RAB5C	-8174
RIN3	-8121
RIC1	-8052
RAB27A	-7978
YWHAE	-7851
RAB11B	-7842
TRAPPC12	-7709
RAB6B	-7399
MADD	-7059
RABGAP1	-6953
TRAPPC13	-6806
RABEP1	-6739
TRAPPC9	-6509
TBC1D16	-6085
TBC1D15	-6069
RAB18	-5919
RAB4A	-5793
DENND1C	-5772
GGA2	-5735
GGA3	-5371
TRAPPC6B	-5062
DENND1B	-5024
RAB14	-4878
DENND6A	-4825
DENND5A	-4768
DENND1A	-4655
TRAPPC1	-4197
RAB5B	-4193
TRAPPC3	-3911
TRAPPC4	-3732
RABGEF1	-3279
TRAPPC6A	-3225
DENND4C	-3218
RAB10	-3046
AKT3	-2517
RAB8A	-2070
MAP1LC3B	-2004
RAB7A	-1836
DENND6B	-1801
TSC1	-1502
RAB27B	-1477
GABARAPL2	-1455
RAB33B	-1349
TRAPPC8	-1336
GABARAP	-1294
RAB3A	-912
RAB11A	-847
SBF2	-536
TBC1D7	-442
RAB6A	-286
DENND2A	-110
RAB31	-104
ALS2	-102
RGP1	64
OPTN	913
DENND4A	1408
MON1A	1411
TBC1D10B	1494
RAB3GAP1	1867
DENND2C	2063
RAB1B	2396
GAPVD1	3219
RAB3IP	3308
SYTL1	3666
TRAPPC5	3682
RIN2	3851
DENND5B	4139
RAB3GAP2	4503
ALS2CL	4513
RAB13	4624
TBC1D17	4983
TRAPPC11	5030
RAB5A	5433
DENND2B	5587
RAB8B	5905
DENND2D	6323
RAB21	7366
RAB3IL1	7383
RAB1A	7620
RINL	7821
RAB12	8283
GDI2	8312
RAB39A	8923
CHML	9497
TBC1D10C	9599

---

REACTOME_RAC2_GTPASE_CYCLE

REACTOME_RAC2_GTPASE_CYCLE

	1373
set	REACTOME_RAC2_GTPASE_CYCLE
setSize	81
pANOVA	0.00373
s.dist	-0.186
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PREX1	-11127
RACGAP1	-10526
NCF2	-10203
CYFIP1	-10047
GIT1	-9920
PGRMC2	-9912
MCAM	-9835
ANKLE2	-9272
ITGB1	-9073
ESYT1	-9061
ARHGAP17	-8957
NCF4	-8612
PIK3R1	-8469
PAK4	-8450
NCKAP1L	-8389
BRK1	-7841
ABR	-7628
VANGL1	-7498
ARHGAP26	-7366
TAOK3	-7221

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PREX1	-11127
RACGAP1	-10526
NCF2	-10203
CYFIP1	-10047
GIT1	-9920
PGRMC2	-9912
MCAM	-9835
ANKLE2	-9272
ITGB1	-9073
ESYT1	-9061
ARHGAP17	-8957
NCF4	-8612
PIK3R1	-8469
PAK4	-8450
NCKAP1L	-8389
BRK1	-7841
ABR	-7628
VANGL1	-7498
ARHGAP26	-7366
TAOK3	-7221
SLITRK5	-7175
CDC42	-7164
TFRC	-7152
ARHGAP1	-7025
BCR	-6531
VAV3	-6523
PIK3R2	-6257
DOCK3	-6155
PAK2	-5763
LAMTOR1	-5574
VAV2	-5410
PLD2	-5090
LMAN1	-5039
SYDE1	-4999
VAPB	-4633
ARHGAP21	-4511
ABI2	-4422
EPHA2	-4298
IQGAP1	-4277
GIT2	-4248
SWAP70	-3638
DOCK2	-3481
VRK2	-3354
LEMD3	-3030
ARHGAP39	-2999
LBR	-2962
ERBIN	-2546
VAMP3	-2222
DOCK1	-1837
RAB7A	-1836
TMPO	-1808
SAMM50	-1778
WASF2	-1372
NCKAP1	-1320
STBD1	-1269
ARHGAP35	-669
CYBA	-592
MPP7	-547
ABI1	-466
RAC2	-415
ARHGDIA	-335
VAV1	-323
DEPDC1B	418
DOCK10	761
PAK1	1260
TRIO	1806
PIK3CA	2017
GARRE1	2083
DIAPH3	2307
BAIAP2L1	2411
CDC42EP4	3116
DOCK4	3500
DEF6	3729
DSG2	4141
PIK3R3	4324
MTX1	4706
TIAM1	4715
ARHGAP42	7588
ARHGAP32	7862
CDC42EP1	8007
CAV1	8260

---

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

	1024
set	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION
setSize	1356
pANOVA	0.00379
s.dist	-0.0469
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	-12026
RAB44	-11827
LY6D	-11823
FCGR3B	-11819
PIGU	-11787
EEF2KMT	-11760
METTL22	-11741
AXIN1	-11718
B4GAT1	-11715
MTA1	-11612
NRN1L	-11579
H2BC26	-11565
AMDHD2	-11555
NPLOC4	-11550
FURIN	-11533
PRSS41	-11489
PNPLA2	-11444
CDC34	-11430
GPIHBP1	-11428
YY1	-11411

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	-12026.0
RAB44	-11827.0
LY6D	-11823.0
FCGR3B	-11819.0
PIGU	-11787.0
EEF2KMT	-11760.0
METTL22	-11741.0
AXIN1	-11718.0
B4GAT1	-11715.0
MTA1	-11612.0
NRN1L	-11579.0
H2BC26	-11565.0
AMDHD2	-11555.0
NPLOC4	-11550.0
FURIN	-11533.0
PRSS41	-11489.0
PNPLA2	-11444.0
CDC34	-11430.0
GPIHBP1	-11428.0
YY1	-11411.0
PIGC	-11365.0
ARF1	-11363.0
BTBD6	-11339.0
DNAJC3	-11234.0
NOD2	-11218.0
INCENP	-11201.0
ST3GAL4	-11197.0
WDR5	-11145.0
H2AC25	-11059.0
P4HB	-11055.0
B4GALT2	-11033.0
PPP6R3	-11022.0
PIGY	-11003.0
RPN1	-10989.0
RHOA	-10972.0
TPST2	-10966.0
CTSZ	-10925.0
ST3GAL6	-10924.0
PSCA	-10919.0
LAMB2	-10913.0
DNMT1	-10881.0
CTBP1	-10802.0
GALNT12	-10796.0
CSNK1D	-10770.0
APOA5	-10728.0
DCUN1D1	-10726.0
NCOR2	-10707.0
FOXK2	-10703.0
CCNF	-10688.0
ASGR2	-10679.0
C4A	-10672.5
B4GALT1	-10659.0
MARCHF6	-10597.0
HGS	-10582.0
MGAT4B	-10564.0
TADA2B	-10549.0
TRAPPC10	-10547.0
PIGX	-10538.0
ALG10	-10517.0
TBC1D20	-10498.0
GMPPA	-10480.0
JOSD2	-10455.0
DCUN1D2	-10452.0
PREB	-10446.0
DDB1	-10439.0
MOGS	-10437.0
APOA2	-10415.0
RCN1	-10397.0
ASB17	-10378.0
RXRA	-10375.0
MAVS	-10369.0
TRAF2	-10365.0
CLSPN	-10308.0
TRAF6	-10304.0
ART3	-10275.0
ASB6	-10271.0
NEU2	-10268.0
CUL9	-10218.0
B3GNTL1	-10189.0
GANAB	-10178.0
RAB32	-10171.0
GOSR2	-10162.0
RAB40C	-10145.0
USP10	-10138.0
TRAPPC2L	-10112.0
MUC5B	-10096.0
RAB25	-10092.0
COPS5	-10067.0
KAT2B	-10050.0
FUCA2	-10049.0
PSMD2	-10038.0
FBXO6	-10036.0
DYNC1LI2	-10030.0
ARRB1	-10007.0
QSOX1	-9988.0
TTLL13	-9984.0
RAB40B	-9983.0
C3	-9967.0
CUL3	-9965.0
PMM2	-9960.0
POMT2	-9916.0
RAB38	-9888.0
STX5	-9876.0
PEX10	-9869.0
LY6G6C	-9863.0
CUL7	-9850.0
FBXL20	-9845.0
GALNT1	-9831.0
DPM1	-9801.0
ST3GAL2	-9798.0
TUBA3C	-9788.0
CREBBP	-9764.0
FOXK1	-9760.0
F2	-9740.0
TUBB1	-9731.0
RAB17	-9730.0
TRRAP	-9712.0
WDR20	-9653.0
OTUD7B	-9641.0
AREG	-9604.0
PRSS21	-9602.0
ST8SIA3	-9601.0
RNF40	-9583.0
MVD	-9581.0
PPARA	-9572.0
FBXL18	-9568.0
PIGG	-9563.0
FBXL19	-9551.0
RNF135	-9502.0
HIPK2	-9492.0
WSB2	-9468.0
SP3	-9441.0
LYPD5	-9401.0
RAET1L	-9397.0
SEC16A	-9376.0
TTLL2	-9319.0
ING2	-9315.0
DYNLL2	-9313.0
RELA	-9312.0
ANKRD9	-9296.0
NPL	-9262.0
H2BC1	-9258.0
ACTR8	-9243.0
TUBA1C	-9236.0
TGFA	-9233.0
TRIM27	-9195.0
NUDT14	-9194.0
RAB2A	-9189.0
RAB35	-9152.0
SUDS3	-9102.0
VDAC1	-9100.0
RIPK1	-9090.0
DPH7	-9088.0
UBXN7	-9085.0
RAD23A	-9072.0
UHRF2	-9050.0
ADAMTS5	-9007.0
UBE2I	-8988.0
NUP62	-8984.0
RAB4B	-8972.0
PHC2	-8971.0
TUBA3E	-8966.0
USP24	-8965.0
H2BC13	-8955.0
DPP3	-8943.0
CP	-8942.0
UBE2F	-8934.0
RAET1G	-8916.0
H2AC1	-8908.0
LMAN1L	-8877.0
RNF144A	-8872.0
MUC3A	-8814.0
MBTPS1	-8808.0
DNMT3A	-8756.0
SRD5A3	-8754.0
SERPINA1	-8752.0
DDA1	-8748.0
GPS1	-8747.0
TGFB1	-8731.0
NUCB1	-8714.0
RANGAP1	-8701.0
DAG1	-8663.0
SEC31A	-8587.0
ARF3	-8585.0
SLC35C1	-8564.0
RAD18	-8560.0
UAP1	-8507.0
CHD3	-8493.0
ALG8	-8471.0
B4GALT5	-8464.0
ARFGAP2	-8462.0
ARSI	-8459.0
CD59	-8454.0
ALG12	-8435.0
H2AC12	-8434.0
LMAN2	-8427.0
ENGASE	-8400.0
ANO8	-8364.0
H2AC15	-8351.0
PIGB	-8311.0
DCTN2	-8285.0
H2AC16	-8268.0
ACTR5	-8263.0
TMED10	-8244.0
UBE2R2	-8190.0
NUP188	-8183.0
RAB5C	-8174.0
PSMB7	-8167.0
GFUS	-8162.0
NUP93	-8160.0
TTLL3	-8156.0
ST6GALNAC6	-8105.0
DERL2	-8084.0
USP34	-8072.0
NUP42	-8070.0
KEAP1	-8063.0
FBXW10	-8054.0
VCP	-8043.0
FN3K	-8024.0
TP53	-8010.0
MGAT3	-8000.0
TTLL12	-7987.0
IGFBP3	-7985.0
RAB27A	-7978.0
CHST10	-7977.0
SHISA5	-7936.0
ADRM1	-7931.0
STAM2	-7929.0
ASB1	-7922.0
GMPPB	-7894.0
SUMF1	-7891.0
PSMD8	-7863.0
METTL21A	-7844.0
RAB11B	-7842.0
ADAMTS13	-7829.0
UBE2L3	-7826.0
ADAMTS10	-7822.0
DYNC1H1	-7804.0
TTLL1	-7801.0
TNIP1	-7792.0
DPH5	-7763.0
UBA3	-7758.0
PMM1	-7757.0
NUP37	-7738.0
DCAF8	-7716.0
ARFGAP1	-7715.0
PGR	-7713.0
AGTPBP1	-7699.0
UBE2J2	-7667.0
GBF1	-7657.0
COG4	-7656.0
TRIM28	-7633.0
RING1	-7616.0
DOLPP1	-7586.0
COMMD3	-7577.0
SPSB3	-7575.0
VASH1	-7527.0
BLM	-7515.0
FCSK	-7472.0
DCTN4	-7465.0
HDAC4	-7446.0
HERC2	-7429.0
OTUD3	-7407.0
AMFR	-7404.0
RAB6B	-7399.0
APOL1	-7394.0
SIAH2	-7346.0
FBXO10	-7345.0
BIRC5	-7316.0
ASGR1	-7305.0
PIGQ	-7300.0
NSF	-7297.0
INO80E	-7291.0
ADAMTS1	-7261.0
H2AC21	-7252.0
H2BC15	-7227.0
ADAMTSL5	-7209.0
RTF1	-7153.0
FN3KRP	-7150.0
ARRB2	-7141.0
DHDDS	-7131.0
USP7	-7121.0
H2BC11	-7099.0
ZRANB1	-7074.0
IZUMO1R	-7062.0
H2BC8	-7060.0
OBSL1	-7042.0
USP20	-6998.0
CUL4A	-6991.0
PRMT3	-6984.0
H2BC10	-6977.0
GORASP1	-6962.0
MBD6	-6941.0
FBXO7	-6937.0
USP19	-6913.0
TFAP2B	-6892.0
VNN2	-6887.0
GOLGB1	-6873.0
ASB14	-6855.0
GOLGA2	-6845.0
GGCX	-6828.0
MBD1	-6817.0
NRIP1	-6815.0
DPM3	-6760.0
NUP85	-6754.0
H2AC8	-6751.0
H2AC13	-6730.0
AGBL5	-6725.0
UBE2G1	-6699.0
RAD21	-6668.0
L3MBTL2	-6664.0
GALNT16	-6646.0
LHB	-6642.0
COPA	-6640.0
PRKDC	-6637.0
PSME4	-6624.0
FBXO31	-6613.0
USP13	-6604.0
PIGS	-6599.0
ARFGAP3	-6592.0
COG3	-6530.0
TRAPPC9	-6509.0
VDAC2	-6497.0
CCNA1	-6496.0
KCTD7	-6492.0
EEF2	-6398.0
NAPG	-6394.0
PML	-6388.0
FBXO30	-6384.0
GALNT3	-6370.0
KLHL5	-6369.0
ASB7	-6336.0
TTLL4	-6314.0
UBE2G2	-6307.0
UBE2E1	-6295.0
ASB2	-6285.0
XPC	-6282.0
LRRC41	-6274.0
WFS1	-6273.0
CAND1	-6264.0
CALM1	-6248.0
COMMD5	-6242.0
SMAD2	-6230.0
NAE1	-6203.0
PROC	-6195.0
AAAS	-6185.0
CMAS	-6173.0
TFAP2A	-6169.0
NSMCE2	-6161.0
COPS7B	-6154.0
SCG3	-6152.0
CUL5	-6115.0
MBD5	-6107.0
RAB15	-6094.0
GLB1	-6067.0
MGAT1	-6065.0
H2BC21	-6060.0
FBXW11	-6050.0
H2AC6	-6049.0
TMED3	-6010.0
NEU1	-6004.0
PIAS4	-5999.0
H4C13	-5978.0
ELOB	-5946.0
RAB18	-5919.0
PRND	-5905.0
ANKRD28	-5892.0
CUL1	-5886.0
ST6GALNAC2	-5883.0
USP42	-5869.0
LYPD4	-5868.0
TMED2	-5863.0
SERPIND1	-5861.0
RAB4A	-5793.0
PENK	-5777.0
SMAD4	-5774.0
KIN	-5740.0
BMP4	-5721.0
ZBTB16	-5711.0
FBXW5	-5700.0
CTSA	-5671.0
TPST1	-5669.0
ADAMTS19	-5658.0
MFGE8	-5651.0
MUL1	-5643.0
RAB22A	-5604.0
JOSD1	-5602.0
DDOST	-5593.0
ACTR1A	-5584.0
NUP58	-5568.0
COPS7A	-5567.0
GALNT10	-5453.0
FBXO41	-5439.0
FAM20A	-5434.0
RTN4RL1	-5416.0
PIGP	-5407.0
WDTC1	-5385.0
COMMD8	-5382.0
COPE	-5379.0
DCAF5	-5355.0
MRTFA	-5354.0
ST8SIA5	-5352.0
RAB36	-5341.0
COPS6	-5338.0
USP37	-5335.0
LARGE2	-5321.0
NLRP3	-5298.0
NUS1	-5279.0
LYPD1	-5277.0
STAMBPL1	-5249.0
B3GNT3	-5241.0
TRAF3	-5228.0
UBE2M	-5223.0
GALNT2	-5200.0
USP48	-5195.0
B4GALT6	-5186.0
PSMD13	-5161.0
SEC24B	-5148.0
SKP1	-5130.0
SMAD3	-5128.0
OTUB2	-5125.0
DOLK	-5122.0
KLHL22	-5121.0
COPZ1	-5093.0
MUCL1	-5086.0
B3GNT8	-5082.0
TRAPPC6B	-5062.0
FBXO11	-5060.0
USP15	-5047.0
POMGNT1	-5040.0
LMAN1	-5039.0
NSMCE1	-5035.0
B3GLCT	-4986.0
FBXW2	-4958.0
B3GNT7	-4947.0
RAB14	-4878.0
SPTAN1	-4822.0
UBE2H	-4819.0
FBXL15	-4791.0
OTUB1	-4738.0
NR4A2	-4734.0
NR1H2	-4713.0
CBX8	-4711.0
ADAMTS18	-4710.0
CNIH3	-4703.0
PIAS3	-4688.0
RRAGA	-4672.0
GAN	-4663.0
CCNA2	-4657.0
GMDS	-4621.0
WSB1	-4612.0
KBTBD8	-4599.0
KLHL42	-4579.0
USP16	-4571.0
UGGT1	-4569.0
ART4	-4567.0
RCE1	-4564.0
NUP210	-4548.0
RAE1	-4537.0
CKAP4	-4522.0
TNKS	-4517.0
KBTBD7	-4510.0
SENP5	-4509.0
MAN2A1	-4502.0
NUP35	-4494.0
PSMB2	-4485.0
MCRS1	-4479.0
DCAF4	-4469.0
PSMD5	-4468.0
APLP2	-4403.0
VCPIP1	-4379.0
PSMD4	-4377.0
FBXO21	-4373.0
UBXN1	-4363.0
USP14	-4362.0
ASB13	-4358.0
FUOM	-4357.0
RAB24	-4350.0
ASB3	-4339.0
GATA3	-4331.0
UBE2W	-4328.0
PSMD1	-4322.0
NFE2L2	-4319.0
USP25	-4267.0
RAD23B	-4226.0
SKIC8	-4219.0
MATN3	-4206.0
TRAPPC1	-4197.0
RAB5B	-4193.0
COPS3	-4178.0
KLHL2	-4168.0
PUM2	-4153.0
LAMB1	-4152.0
SEL1L	-4135.0
SQSTM1	-4128.0
ADAMTS20	-4125.0
TNIP2	-4114.0
USP30	-4102.0
SEC24C	-4094.0
NUP205	-4091.0
AMTN	-4085.0
RNF103	-4062.0
UIMC1	-4038.0
FAM20C	-4030.0
TMED9	-4026.0
PSMC1	-4003.0
TULP4	-4002.0
TUSC3	-3991.0
MEN1	-3969.0
GALNT11	-3962.0
CDC73	-3958.0
EDEM2	-3940.0
GALNT7	-3919.0
TRAPPC3	-3911.0
NSMCE4A	-3907.0
POMT1	-3895.0
KDELR2	-3890.0
SENP8	-3851.0
ALG5	-3844.0
GNE	-3830.0
PSMF1	-3800.0
PSMB10	-3782.0
NR5A1	-3765.0
UMOD	-3763.0
SKP2	-3756.0
CBX2	-3745.0
FBXL8	-3744.0
ALG3	-3738.0
FBXO9	-3733.0
TRAPPC4	-3732.0
PSMB9	-3711.0
EP300	-3709.0
USP4	-3703.0
TUBB2A	-3682.0
IL6	-3644.0
DYNC1LI1	-3617.0
CDH2	-3603.0
TRIM25	-3581.0
PIAS1	-3564.0
ERCC8	-3550.0
TRIM4	-3505.0
DCUN1D3	-3493.0
IDE	-3478.0
CGA	-3466.0
SUZ12	-3439.0
LYPD2	-3430.0
USP49	-3422.0
SSPOP	-3404.0
ARSK	-3403.0
MYSM1	-3377.0
COMMD7	-3361.0
GPLD1	-3341.0
SMAD7	-3334.0
SPON2	-3330.0
EIF5A2	-3318.0
COPB2	-3316.0
PHC3	-3311.0
COPG1	-3289.0
H2BC5	-3284.0
GCNT7	-3250.0
SEC23IP	-3247.0
THSD1	-3228.0
H2BC12	-3226.0
TRAPPC6A	-3225.0
SYVN1	-3216.0
FN1	-3169.0
ADAMTS3	-3158.0
CAPZA2	-3154.0
COPS4	-3148.0
RNF20	-3138.0
SEC22A	-3132.0
CNIH1	-3109.0
ALG14	-3097.0
PIGN	-3091.0
LSAMP	-3088.0
STAG1	-3054.0
RAB10	-3046.0
GALNT17	-3039.0
OTOA	-3004.0
FOLR2	-2988.0
B3GNT2	-2985.0
ADAMTS16	-2920.0
TOP2B	-2870.0
NUP155	-2868.0
CUL2	-2866.0
MSLN	-2861.0
FBXL16	-2856.0
NEU4	-2846.0
ASB10	-2842.0
ARSB	-2835.0
RNF185	-2795.0
ETFBKMT	-2780.0
FPGT	-2768.0
NR5A2	-2741.0
HNRNPC	-2737.0
ST3GAL1	-2708.0
RAB2B	-2667.0
H2AC20	-2661.0
TTLL7	-2656.0
COG1	-2647.0
SPSB1	-2640.0
NANP	-2598.0
KLHL11	-2575.0
RBX1	-2572.0
ZNF350	-2559.0
UBE2V2	-2507.0
PEX14	-2506.0
EVA1A	-2494.0
NAGK	-2480.0
COP1	-2446.0
DPH6	-2432.0
COPS8	-2428.0
KCTD6	-2417.0
PROZ	-2404.0
HDAC2	-2399.0
UBD	-2396.0
POM121C	-2389.0
RARA	-2388.0
PSMB11	-2381.0
IGFBP5	-2362.0
DDX5	-2348.0
DPH1	-2341.0
IGFBP7	-2340.0
PIGV	-2335.0
USP47	-2318.0
MAN1B1	-2317.0
ANK3	-2306.0
RNF139	-2304.0
FBXW8	-2295.0
CNTN5	-2294.0
VCPKMT	-2292.0
ICMT	-2289.0
TUBA1A	-2281.0
PSMA5	-2270.0
RNF146	-2262.0
STC2	-2254.0
LY6K	-2215.0
PCSK9	-2205.0
EDEM3	-2198.0
HDAC1	-2197.0
PROS1	-2193.0
NR1H3	-2192.0
KAT2A	-2185.0
ESR1	-2162.0
HDAC7	-2148.0
VDR	-2141.0
UBE2K	-2135.0
RAB20	-2121.0
SEC24D	-2117.0
SNX3	-2114.0
NOD1	-2098.0
XRCC4	-2091.0
VWA1	-2088.0
FOLR1	-2084.0
RAB8A	-2070.0
NCOA2	-2061.0
GFPT2	-2053.0
TRIM13	-2043.0
NTM	-2038.0
RAB37	-2035.0
GALNT9	-2007.0
PEX2	-2005.0
ATXN7	-1970.0
GOSR1	-1952.0
ARCN1	-1947.0
SPP2	-1938.0
TP53BP1	-1919.0
DCUN1D5	-1914.0
DAXX	-1902.0
BABAM2	-1899.0
PEX5	-1881.0
B4GALT4	-1879.0
RAB7A	-1836.0
C1GALT1	-1832.0
TGFBR2	-1829.0
PIGM	-1818.0
ST6GAL2	-1781.0
NUP214	-1777.0
INO80	-1769.0
B3GNT6	-1766.0
BRCA1	-1738.0
NFKB2	-1736.0
RECK	-1733.0
TAB1	-1680.0
USP2	-1679.0
NUP133	-1674.0
TUBAL3	-1663.0
BAP1	-1660.0
NUP88	-1654.0
PLAUR	-1650.0
COG7	-1639.0
EEF1AKMT2	-1629.0
SPTBN1	-1621.0
COMMD1	-1585.0
BET1L	-1567.0
STAM	-1561.0
COPG2	-1557.0
SOCS3	-1554.0
B3GNT5	-1544.0
H4C2	-1542.0
HNRNPK	-1521.0
SENP2	-1517.0
KDM1B	-1516.0
STX17	-1492.0
MAN2A2	-1488.0
ADAMTS2	-1486.0
DNMT3B	-1481.0
RAB27B	-1477.0
ST3GAL3	-1475.0
RABGGTA	-1471.0
ARF5	-1444.0
TFAP2C	-1435.0
ARSG	-1418.0
INO80C	-1408.0
FBXL7	-1403.0
NUP98	-1397.0
RAD52	-1350.0
RAB33B	-1349.0
SEM1	-1346.0
LMAN2L	-1345.0
PIGK	-1339.0
USP12	-1331.0
ALG6	-1312.0
AGBL2	-1286.0
MELTF	-1279.0
CNTN3	-1267.0
AXIN2	-1260.0
DDB2	-1259.0
THBS2	-1230.0
MIA2	-1228.0
PSMD6	-1201.0
TPGS1	-1196.0
TPR	-1191.0
NANS	-1176.0
MAN1A2	-1170.0
TTLL9	-1168.0
FBXO2	-1166.0
RPA1	-1159.0
MUC16	-1152.0
MIA3	-1128.0
BARD1	-1096.0
PCGF2	-1042.0
SPSB2	-1028.0
APOA1	-1006.0
NEURL2	-997.0
RAB3A	-912.0
KBTBD6	-909.0
PHC1	-905.0
CDCA8	-902.0
ALG11	-896.0
CANX	-890.0
DCAF6	-856.0
RAB11A	-847.0
UBE2E3	-839.0
FUT8	-833.0
ADAMTS17	-825.0
SUMO1	-805.0
PALB2	-791.0
THRA	-789.0
LTBP1	-779.0
VNN1	-770.0
KNG1	-753.0
HSPA8	-751.0
DHPS	-719.0
TUBA4B	-707.0
LARGE1	-706.0
UBE2N	-700.0
EID3	-677.0
H2BC4	-667.0
MUC17	-651.0
ZNF131	-637.0
AGBL3	-620.0
CALR	-616.0
NRN1	-602.0
ADAMTSL2	-596.0
PIGF	-590.0
POMGNT2	-579.0
EEF1AKMT1	-564.0
ALPI	-545.0
PSMB6	-534.0
DMP1	-520.0
SOCS5	-494.0
CTR9	-472.0
ALG9	-406.0
DYNC1I2	-374.0
FBN1	-352.0
TTLL11	-337.0
PSMC4	-326.0
B3GALNT2	-307.0
COG5	-300.0
FBXL3	-297.0
TMEM115	-287.0
RAB6A	-286.0
MUC5AC	-258.0
USP5	-257.0
SMC5	-256.0
ADAMTS15	-242.0
RNF168	-229.0
SUMO2	-224.0
NTNG1	-182.0
ARSA	-175.0
B4GALNT2	-174.0
INO80D	-109.0
RNF123	-108.0
RAB31	-104.0
ASB16	-88.0
NUP50	-64.0
PSMA3	-63.0
FBXO27	-35.0
ST6GALNAC5	-33.0
DYNLL1	26.0
NOP58	31.0
PSMA8	45.0
ADAMTS9	49.0
PEX12	57.0
DCTN1	60.0
SPTBN4	74.0
VCAN	100.0
H4C8	118.0
FBXO44	144.0
DERL1	151.0
UCHL5	161.0
FSTL3	166.0
YOD1	171.0
ABRAXAS2	174.0
SERPINA10	175.0
PSMA1	206.0
MEPE	229.0
PLET1	240.0
GCNT1	246.0
PPP6R1	248.0
SMC3	296.0
SEC22C	353.0
PSMD9	385.0
SPSB4	386.0
TUBB6	387.0
ADAMTS4	396.0
KDELR1	413.0
IKBKE	423.0
FBXL14	459.0
PIGT	467.0
FBXL5	478.0
SBSPON	501.0
PSMC3	511.0
PDIA6	538.0
PPARG	544.0
CAPZA1	546.0
B3GNT4	547.0
H4C3	548.0
UFD1	551.0
PTRH2	560.0
PSME1	574.0
SMAD1	578.0
SPTB	606.0
POFUT2	627.0
ACTL6A	666.0
SAFB	670.0
PPP6C	723.0
SPP1	725.0
TPGS2	738.0
ADAMTS7	748.0
MDGA2	755.0
GFPT1	756.0
THRB	770.0
CST3	792.0
RAB43	796.0
ULBP2	804.0
FUCA1	820.0
ASB4	836.0
OPCML	853.0
EDEM1	890.0
SLC35A1	912.0
COL7A1	936.0
APP	942.0
BECN1	958.0
TOP2A	959.0
MAT2B	968.0
ASB18	976.0
BTBD1	978.0
TUBA4A	1016.0
TDG	1021.0
CNTN4	1024.0
NDC1	1029.0
MGAT4A	1034.0
SEC23A	1053.0
COG8	1061.0
LYPD8	1092.0
SPTA1	1100.0
MGAT5	1101.0
B3GNT9	1144.0
DCAF11	1157.0
H2AC4	1158.0
USP8	1171.0
UBA2	1179.0
ALPL	1205.0
TTL	1207.0
COMMD6	1222.0
NUB1	1231.0
USP3	1244.0
SEH1L	1257.0
NEU3	1259.0
RIGI	1281.0
TUBA1B	1291.0
ASB8	1315.0
OS9	1322.0
DCTN3	1324.0
CALU	1340.0
BGLAP	1369.0
CDKN2A	1410.0
SMURF2	1414.0
NFRKB	1416.0
MUC12	1420.0
GALNT14	1438.0
F10	1453.0
HIF3A	1466.0
PSMD12	1473.0
SPRN	1478.0
MAN1A1	1485.0
CHST8	1510.0
MDM4	1531.0
TUBA8	1565.0
UBE2T	1568.0
WAC	1572.0
UGGT2	1620.0
DPM2	1632.0
ST3GAL5	1646.0
EPAS1	1654.0
VHL	1667.0
ETFB	1706.0
CNIH2	1707.0
UBE2D2	1756.0
TUBB8	1769.0
TMED7	1779.0
TTLL5	1793.0
USP22	1819.0
UBE2D3	1842.0
NAPA	1853.0
PIGH	1882.0
H2AC7	1901.5
H2BC7	1901.5
ANK2	1944.0
STAMBP	1946.0
MCFD2	1949.0
USP21	1965.0
ST8SIA6	1969.0
GNPNAT1	1971.0
CDC25A	1996.0
EIF5A	2015.0
UBE2D1	2022.0
DPH3	2038.0
MDM2	2081.0
APOB	2093.0
RAB23	2098.0
PSMD11	2103.0
SEMA5A	2121.0
COG2	2126.0
ST6GALNAC4	2129.0
RUVBL1	2146.0
DNAJC24	2160.0
VDAC3	2180.0
FBXL12	2212.0
PTEN	2245.0
CBX4	2250.0
SOCS2	2259.0
UBA6	2281.0
SHPRH	2295.0
DDX17	2329.0
PIGL	2345.0
FEM1C	2379.0
GALNT5	2383.0
CBX5	2394.0
RANBP2	2395.0
RAB1B	2396.0
SPTBN5	2404.0
USO1	2420.0
LYPD6B	2438.0
GALNTL6	2439.0
APC	2461.0
SOCS6	2507.0
UCHL1	2530.0
DTL	2535.0
BST1	2539.0
WRN	2548.0
USP33	2555.0
NGLY1	2563.0
RABGGTB	2570.0
COG6	2574.0
SIN3A	2603.0
HLA-A	2617.0
UBE2Z	2645.0
NCOA1	2647.0
CDKN1A	2683.0
GCNT3	2684.0
POLB	2698.0
SEMA5B	2706.0
EEF1A1	2745.0
RFT1	2758.0
BMI1	2773.0
MUC15	2814.0
RWDD3	2821.0
GOLM1	2840.0
DCUN1D4	2877.0
FBXL13	2879.0
TUBB4A	2909.0
COMMD9	2910.0
PSME3	2934.0
THY1	2948.0
MLEC	3021.0
CDC20	3030.0
GALNT15	3033.0
ABRAXAS1	3078.0
MUC4	3092.0
H2AC11	3095.0
NR1H4	3110.0
TUBB3	3143.0
FBXW7	3145.0
MAN1C1	3148.0
MUC6	3184.0
RNF2	3188.0
TOP1	3201.0
NFKBIA	3202.0
SATB2	3218.0
NICN1	3235.0
SUMO3	3241.0
AHSG	3250.0
NTNG2	3273.0
TGFBR1	3279.0
PSMD14	3291.0
KLHL3	3293.0
ST8SIA4	3299.0
MDC1	3339.0
PRKN	3347.0
ST6GAL1	3359.0
MDGA1	3362.0
POMK	3387.0
PGAP1	3446.0
RAB19	3467.0
GCNT4	3485.0
ALPG	3493.0
ARSJ	3502.0
SUMF2	3509.0
POM121	3526.0
GALNT13	3539.0
SAR1B	3547.0
PSMD3	3550.0
TFG	3563.0
SELENOS	3574.0
IGFBP1	3621.0
LY6G6D	3634.0
FGF23	3639.0
NAPB	3648.0
PSMC5	3651.0
TECTA	3655.0
PIGW	3664.0
TRAPPC5	3682.0
ANK1	3694.0
PPARGC1A	3706.0
LY6E	3718.0
ST6GALNAC3	3722.0
AMBN	3738.0
PSMA2	3743.0
APOE	3745.0
MGAT4C	3755.0
GALNT6	3773.0
F5	3783.0
SCMH1	3791.0
RPS2	3798.0
KLHL25	3818.0
DAD1	3832.0
FBXL22	3838.0
GALNTL5	3862.0
IFIH1	3865.0
LY6H	3866.0
THSD7A	3869.0
BIRC2	3936.0
H2BC3	3960.0
RTN4RL2	3964.0
SAE1	3978.0
RNF181	3980.0
USP28	3987.0
TNKS2	4005.0
ASXL2	4038.0
SLC17A5	4039.0
CAPZB	4075.0
BCL10	4080.0
TFPT	4086.0
LEO1	4094.0
CAMKMT	4105.0
NR1I2	4109.0
DCAF13	4111.0
PIAS2	4117.0
SCFD1	4119.0
RORA	4123.0
MITF	4138.0
SMC6	4145.0
MPI	4161.0
BIRC3	4171.0
CDK1	4175.0
PEX13	4183.0
TNFAIP3	4187.0
UCHL3	4204.0
RAB34	4205.0
SP100	4216.0
FOXL2	4237.0
CCP110	4250.0
FKBP8	4254.0
PSMC6	4259.0
DCAF7	4286.0
HIF1A	4305.0
PARP1	4313.0
CD109	4318.0
H4C5	4340.0
RIPK2	4343.0
DCAF10	4359.0
PSMD7	4369.0
ALB	4370.0
PSMB8	4390.0
ASB15	4393.0
FBXO17	4399.0
DYNC1I1	4409.0
CSF1	4410.0
MANEA	4421.0
INO80B	4426.0
DPH2	4428.0
FBXO40	4460.0
PSMA7	4493.0
ADRB2	4529.0
RAB3D	4535.0
RAB3C	4550.0
BABAM1	4556.0
PSMB4	4570.0
MXRA8	4615.0
RAB13	4624.0
SEC22B	4626.0
NR3C1	4678.0
GP2	4680.0
DCTN5	4684.0
ELOC	4694.0
NPM1	4722.0
NR3C2	4723.0
GALNT4	4748.0
SPON1	4761.0
TADA3	4764.0
ADAMTS14	4807.0
TECTB	4832.0
UBE2Q2	4846.0
TOPORS	4848.0
TOMM70	4850.0
ENAM	4854.0
TTLL8	4877.0
ADAMTSL4	4886.0
LGALS1	4910.0
TTLL10	4923.0
RBBP5	4947.0
THBS1	4979.0
ADAMTS8	4989.0
ALG2	4997.0
PSMA6	5015.0
WDR48	5033.0
DOHH	5057.0
KLHL9	5112.0
SERPINC1	5125.0
AURKA	5126.0
CTSC	5130.0
KTN1	5170.0
GPAA1	5171.0
ADAM10	5192.0
FBXW12	5199.0
BET1	5206.0
CPM	5230.0
IGFBP4	5278.0
RHOT1	5281.0
RAB42	5338.0
THSD4	5342.0
CD52	5353.0
UBE2C	5371.0
NUP160	5375.0
HLTF	5381.0
ASB5	5383.0
TNIP3	5400.0
AGBL4	5406.0
RAB5A	5433.0
MYC	5438.0
PCNA	5459.0
CYLD	5465.0
SEC13	5529.0
RNF152	5547.0
PSMB1	5600.0
COMMD4	5615.0
DCTN6	5635.0
CISH	5649.0
BTRC	5660.0
SPTBN2	5686.0
ST8SIA2	5694.0
UBE2B	5705.0
TEX101	5714.0
FEM1A	5732.0
ALG1	5787.0
TOMM20	5791.0
RNF7	5824.0
PRKCSH	5888.0
NEDD8	5890.0
RAB8B	5905.0
MGAT2	5928.5
TMEM129	5981.0
FBXW4	6026.0
FBXW9	6085.0
DPAGT1	6089.0
FBXO15	6098.0
FBXO4	6102.0
NR2C1	6118.0
ACTB	6120.0
SVBP	6135.0
VGF	6156.0
LRRC49	6180.0
SENP1	6187.0
VASH2	6195.0
RPS27A	6202.0
PARK7	6229.0
CD55	6247.0
COMMD10	6301.0
KLHL41	6379.0
SPACA4	6397.0
MAP3K7	6414.0
TGOLN2	6423.0
CCN1	6456.0
KLHL21	6466.0
TNC	6481.0
MUC21	6495.0
TTLL6	6502.0
ADAMTS6	6512.0
LAMC1	6515.0
SDC2	6516.0
NOTUM	6517.0
LYPD3	6532.0
PIGZ	6555.0
RPN2	6556.0
ST8SIA1	6609.0
MUC7	6633.0
NUP153	6647.0
HSP90B1	6662.0
GALNT18	6665.0
COPB1	6688.0
ACTR10	6689.0
RAB26	6717.0
PGM3	6720.0
INS	6732.0
ITIH2	6741.0
PIGO	6745.0
LRR1	6747.0
DCAF17	6764.0
NEGR1	6773.0
PAF1	6778.0
PRSS23	6786.0
H2BC17	6788.0
FBXO22	6805.0
LMO7	6855.0
SEC24A	6864.0
OTUD7A	6868.0
PSMA4	6896.0
NUP43	6907.0
RAB30	6927.0
CHST4	6956.0
B4GALT3	6971.0
TUBB2B	6990.0
UBA52	7023.0
FSTL1	7080.0
UBE2S	7093.0
FGG	7132.0
OTULIN	7136.0
RAB29	7183.0
STT3A	7225.0
MUC1	7245.0
NUP54	7283.0
ALG10B	7292.0
FUT3	7293.0
KLHL20	7296.0
PSME2	7312.0
ADAMTSL1	7333.0
NSMCE3	7334.0
TUBB4B	7335.0
H2BC6	7354.0
RAB21	7366.0
UBC	7391.0
FBXO32	7456.0
FBXL4	7480.0
CCDC8	7488.0
HIC1	7515.0
H4C1	7519.0
THSD7B	7520.0
COPS2	7523.0
A4GNT	7542.0
ADAMTSL3	7560.0
ARF4	7562.0
MPDU1	7567.0
RAB1A	7620.0
H4C11	7668.0
FEM1B	7686.0
SEC16B	7694.0
H4C6	7701.0
NUP107	7722.0
H2AC17	7742.0
AURKB	7777.0
ATXN3	7788.0
USP18	7790.0
MUC13	7805.0
USP44	7834.0
RNF5	7851.0
CFTR	7876.0
H4C16	7938.0
TF	7948.0
F7	7951.0
DCAF16	7973.0
TMEM132A	8011.0
PDIA3	8026.0
H4C4	8046.0
ADAMTS12	8110.0
PSMB5	8115.0
PSMC2	8147.0
CEACAM7	8213.0
UBB	8218.0
PSMB3	8251.0
SCG2	8276.0
RAB12	8283.0
FGA	8332.0
AGBL1	8362.0
H2BC9	8440.5
AFP	8496.0
CAPZA3	8517.0
H2BC14	8529.0
COPZ2	8567.0
H4C9	8578.0
TAF10	8637.0
KDELR3	8719.0
PTP4A2	8727.0
ASXL1	8761.0
RAB3B	8771.0
YKT6	8795.0
SPARCL1	8832.0
COMMD2	8861.0
CHGB	8878.0
RAB39A	8923.0
MUC20	8947.0
H4C12	8975.0
BPIFB2	9128.0
GRIA1	9139.0
CEACAM5	9173.0
ST6GALNAC1	9180.0
GALNT8	9257.0
IL33	9324.0
SATB1	9435.0
CHML	9497.0
H2AC14	9533.0
HRC	9586.0
H2AC18	9604.5
H2AC19	9604.5

---

REACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

REACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

	1057
set	REACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS
setSize	63
pANOVA	0.0038
s.dist	-0.211
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
YWHAB	-11084
MAP2K2	-11023
MAPK3	-10990
HRAS	-10751
CAMK2G	-10103
ARRB1	-10007
TRAK1	-9887
SRC	-9726
KSR1	-9594
NRAS	-9345
TLN1	-9145
CLCN6	-9070
FGB	-8843
AGTRAP	-8466
KRAS	-7903
ITGA2B	-7827
MAPK1	-7647
MPRIP	-7550
PAPSS1	-7510
AP3B1	-7204

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
YWHAB	-11084
MAP2K2	-11023
MAPK3	-10990
HRAS	-10751
CAMK2G	-10103
ARRB1	-10007
TRAK1	-9887
SRC	-9726
KSR1	-9594
NRAS	-9345
TLN1	-9145
CLCN6	-9070
FGB	-8843
AGTRAP	-8466
KRAS	-7903
ITGA2B	-7827
MAPK1	-7647
MPRIP	-7550
PAPSS1	-7510
AP3B1	-7204
TENT4A	-7179
MARK3	-7170
ARRB2	-7141
SND1	-6745
RAP1B	-6680
BRAF	-6254
CALM1	-6248
PEBP1	-6044
ATG7	-6042
KIAA1549	-5922
AKAP9	-5545
JAK2	-5400
QKI	-5059
CNKSR1	-4314
IQGAP1	-4277
FN1	-3169
LMNA	-3017
AGGF1	-2897
RAF1	-2378
TRIM24	-1422
FAM114A2	-1410
VCL	-1222
MAP2K1	-974
BCL2L11	-666
VWF	-172
CAMK2D	-7
KSR2	1188
KDM7A	1506
CAMK2B	1914
RAP1A	2073
FXR1	2291
ACTG1	2573
FAM131B	2577
CSK	3354
ITGB3	3419
APBB1IP	4691
AGK	5106
ESRP1	5405
ACTB	6120
FGG	7132
CAMK2A	7918
ZC3HAV1	8212
FGA	8332

---

REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION

REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION

	786
set	REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION
setSize	299
pANOVA	0.004
s.dist	-0.0968
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TUBA3D	-12026
AMDHD2	-11555
ARF1	-11363
ST3GAL4	-11197
B4GALT2	-11033
PPP6R3	-11022
RPN1	-10989
CTSZ	-10925
ST3GAL6	-10924
CSNK1D	-10770
ASGR2	-10679
B4GALT1	-10659
MARCHF6	-10597
MGAT4B	-10564
TRAPPC10	-10547
ALG10	-10517
TBC1D20	-10498
GMPPA	-10480
PREB	-10446
MOGS	-10437

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TUBA3D	-12026.0
AMDHD2	-11555.0
ARF1	-11363.0
ST3GAL4	-11197.0
B4GALT2	-11033.0
PPP6R3	-11022.0
RPN1	-10989.0
CTSZ	-10925.0
ST3GAL6	-10924.0
CSNK1D	-10770.0
ASGR2	-10679.0
B4GALT1	-10659.0
MARCHF6	-10597.0
MGAT4B	-10564.0
TRAPPC10	-10547.0
ALG10	-10517.0
TBC1D20	-10498.0
GMPPA	-10480.0
PREB	-10446.0
MOGS	-10437.0
NEU2	-10268.0
GANAB	-10178.0
GOSR2	-10162.0
TRAPPC2L	-10112.0
DYNC1LI2	-10030.0
PMM2	-9960.0
STX5	-9876.0
DPM1	-9801.0
ST3GAL2	-9798.0
TUBA3C	-9788.0
TUBB1	-9731.0
AREG	-9604.0
ST8SIA3	-9601.0
MVD	-9581.0
SEC16A	-9376.0
DYNLL2	-9313.0
NPL	-9262.0
TUBA1C	-9236.0
TGFA	-9233.0
NUDT14	-9194.0
TUBA3E	-8966.0
LMAN1L	-8877.0
SRD5A3	-8754.0
SERPINA1	-8752.0
SEC31A	-8587.0
ARF3	-8585.0
SLC35C1	-8564.0
UAP1	-8507.0
ALG8	-8471.0
B4GALT5	-8464.0
ARFGAP2	-8462.0
CD59	-8454.0
ALG12	-8435.0
LMAN2	-8427.0
ENGASE	-8400.0
DCTN2	-8285.0
TMED10	-8244.0
GFUS	-8162.0
ST6GALNAC6	-8105.0
DERL2	-8084.0
VCP	-8043.0
MGAT3	-8000.0
CHST10	-7977.0
GMPPB	-7894.0
DYNC1H1	-7804.0
PMM1	-7757.0
ARFGAP1	-7715.0
GBF1	-7657.0
COG4	-7656.0
DOLPP1	-7586.0
FCSK	-7472.0
DCTN4	-7465.0
AMFR	-7404.0
ASGR1	-7305.0
NSF	-7297.0
DHDDS	-7131.0
GORASP1	-6962.0
GOLGB1	-6873.0
GOLGA2	-6845.0
DPM3	-6760.0
LHB	-6642.0
COPA	-6640.0
ARFGAP3	-6592.0
COG3	-6530.0
TRAPPC9	-6509.0
NAPG	-6394.0
CMAS	-6173.0
GLB1	-6067.0
MGAT1	-6065.0
TMED3	-6010.0
NEU1	-6004.0
ANKRD28	-5892.0
ST6GALNAC2	-5883.0
TMED2	-5863.0
CTSA	-5671.0
DDOST	-5593.0
ACTR1A	-5584.0
COPE	-5379.0
ST8SIA5	-5352.0
NUS1	-5279.0
B4GALT6	-5186.0
SEC24B	-5148.0
DOLK	-5122.0
COPZ1	-5093.0
TRAPPC6B	-5062.0
LMAN1	-5039.0
SPTAN1	-4822.0
CNIH3	-4703.0
GMDS	-4621.0
UGGT1	-4569.0
MAN2A1	-4502.0
UBXN1	-4363.0
FUOM	-4357.0
RAD23B	-4226.0
TRAPPC1	-4197.0
SEL1L	-4135.0
SEC24C	-4094.0
RNF103	-4062.0
TMED9	-4026.0
PSMC1	-4003.0
TUSC3	-3991.0
EDEM2	-3940.0
TRAPPC3	-3911.0
KDELR2	-3890.0
ALG5	-3844.0
GNE	-3830.0
UMOD	-3763.0
ALG3	-3738.0
TRAPPC4	-3732.0
TUBB2A	-3682.0
DYNC1LI1	-3617.0
CGA	-3466.0
COPB2	-3316.0
COPG1	-3289.0
SEC23IP	-3247.0
TRAPPC6A	-3225.0
SYVN1	-3216.0
CAPZA2	-3154.0
SEC22A	-3132.0
CNIH1	-3109.0
ALG14	-3097.0
NEU4	-2846.0
RNF185	-2795.0
FPGT	-2768.0
ST3GAL1	-2708.0
COG1	-2647.0
NANP	-2598.0
NAGK	-2480.0
MAN1B1	-2317.0
ANK3	-2306.0
RNF139	-2304.0
TUBA1A	-2281.0
EDEM3	-2198.0
SEC24D	-2117.0
FOLR1	-2084.0
GFPT2	-2053.0
TRIM13	-2043.0
GOSR1	-1952.0
ARCN1	-1947.0
B4GALT4	-1879.0
ST6GAL2	-1781.0
TUBAL3	-1663.0
COG7	-1639.0
SPTBN1	-1621.0
BET1L	-1567.0
COPG2	-1557.0
STX17	-1492.0
MAN2A2	-1488.0
ST3GAL3	-1475.0
ARF5	-1444.0
LMAN2L	-1345.0
ALG6	-1312.0
MIA2	-1228.0
NANS	-1176.0
MAN1A2	-1170.0
MIA3	-1128.0
ALG11	-896.0
CANX	-890.0
FUT8	-833.0
TUBA4B	-707.0
CALR	-616.0
ALG9	-406.0
DYNC1I2	-374.0
COG5	-300.0
TMEM115	-287.0
B4GALNT2	-174.0
ST6GALNAC5	-33.0
DYNLL1	26.0
DCTN1	60.0
SPTBN4	74.0
DERL1	151.0
PPP6R1	248.0
SEC22C	353.0
TUBB6	387.0
KDELR1	413.0
CAPZA1	546.0
SPTB	606.0
PPP6C	723.0
GFPT1	756.0
FUCA1	820.0
EDEM1	890.0
SLC35A1	912.0
COL7A1	936.0
TUBA4A	1016.0
MGAT4A	1034.0
SEC23A	1053.0
COG8	1061.0
SPTA1	1100.0
MGAT5	1101.0
NEU3	1259.0
TUBA1B	1291.0
OS9	1322.0
DCTN3	1324.0
MAN1A1	1485.0
CHST8	1510.0
TUBA8	1565.0
UGGT2	1620.0
DPM2	1632.0
ST3GAL5	1646.0
CNIH2	1707.0
TUBB8	1769.0
TMED7	1779.0
NAPA	1853.0
ANK2	1944.0
MCFD2	1949.0
ST8SIA6	1969.0
GNPNAT1	1971.0
COG2	2126.0
ST6GALNAC4	2129.0
RAB1B	2396.0
SPTBN5	2404.0
USO1	2420.0
NGLY1	2563.0
COG6	2574.0
RFT1	2758.0
TUBB4A	2909.0
MLEC	3021.0
TUBB3	3143.0
MAN1C1	3148.0
ST8SIA4	3299.0
ST6GAL1	3359.0
SAR1B	3547.0
TFG	3563.0
NAPB	3648.0
TRAPPC5	3682.0
ANK1	3694.0
ST6GALNAC3	3722.0
MGAT4C	3755.0
F5	3783.0
DAD1	3832.0
SLC17A5	4039.0
CAPZB	4075.0
SCFD1	4119.0
MPI	4161.0
DYNC1I1	4409.0
MANEA	4421.0
SEC22B	4626.0
DCTN5	4684.0
ALG2	4997.0
CTSC	5130.0
BET1	5206.0
SEC13	5529.0
DCTN6	5635.0
SPTBN2	5686.0
ST8SIA2	5694.0
ALG1	5787.0
PRKCSH	5888.0
MGAT2	5928.5
DPAGT1	6089.0
RPS27A	6202.0
CD55	6247.0
RPN2	6556.0
ST8SIA1	6609.0
COPB1	6688.0
ACTR10	6689.0
PGM3	6720.0
INS	6732.0
SEC24A	6864.0
B4GALT3	6971.0
TUBB2B	6990.0
UBA52	7023.0
STT3A	7225.0
ALG10B	7292.0
FUT3	7293.0
TUBB4B	7335.0
UBC	7391.0
ARF4	7562.0
MPDU1	7567.0
RAB1A	7620.0
SEC16B	7694.0
RNF5	7851.0
PDIA3	8026.0
UBB	8218.0
CAPZA3	8517.0
COPZ2	8567.0
KDELR3	8719.0
YKT6	8795.0
GRIA1	9139.0
ST6GALNAC1	9180.0

---

REACTOME_INTERLEUKIN_36_PATHWAY

REACTOME_INTERLEUKIN_36_PATHWAY

	1393
set	REACTOME_INTERLEUKIN_36_PATHWAY
setSize	7
pANOVA	0.00403
s.dist	0.628
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
IL36G	9780
IL36A	7726
IL36B	7720
IL1RL2	6590
IL1F10	4973
IL1RAP	2916
IL36RN	677

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
IL36G	9780
IL36A	7726
IL36B	7720
IL1RL2	6590
IL1F10	4973
IL1RAP	2916
IL36RN	677

---

REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET

REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET

	445
set	REACTOME_SYNTHESIS_OF_EPOXY_EET_AND_DIHYDROXYEICOSATRIENOIC_ACIDS_DHET
setSize	8
pANOVA	0.00409
s.dist	0.586
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP2C19	9615
CYP2C9	9440
CYP2C8	8325
CYP1A1	7913
EPHX2	7478
CYP2J2	2860
CYP1B1	231
CYP1A2	-3364

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP2C19	9615
CYP2C9	9440
CYP2C8	8325
CYP1A1	7913
EPHX2	7478
CYP2J2	2860
CYP1B1	231
CYP1A2	-3364

---

REACTOME_SYNTHESIS_OF_PG

REACTOME_SYNTHESIS_OF_PG

	127
set	REACTOME_SYNTHESIS_OF_PG
setSize	8
pANOVA	0.0041
s.dist	-0.586
p.adjustANOVA	0.164

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PLD1	-10696
PGS1	-10563
PTPMT1	-9661
PLD3	-9178
PLD6	-8699
PLD2	-5090
PLD4	-3831
CDS2	-2932

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PLD1	-10696
PGS1	-10563
PTPMT1	-9661
PLD3	-9178
PLD6	-8699
PLD2	-5090
PLD4	-3831
CDS2	-2932

---

REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

	486
set	REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP
setSize	41
pANOVA	0.00451
s.dist	-0.256
p.adjustANOVA	0.174

Top enriched genes

Top 20 genes

GeneID	Gene Rank
LSS	-11419
SREBF1	-11280
CARM1	-10948
RXRA	-10375
SREBF2	-10197
CREBBP	-9764
HMGCS1	-9702
MVD	-9581
PPARA	-9572
ACACB	-9522
FASN	-9192
SQLE	-9083
MTF1	-8251
PMVK	-7938
MED1	-7048
GGPS1	-6842
ACACA	-6054
HELZ2	-5553
DHCR7	-4749
CYP51A1	-4187

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
LSS	-11419
SREBF1	-11280
CARM1	-10948
RXRA	-10375
SREBF2	-10197
CREBBP	-9764
HMGCS1	-9702
MVD	-9581
PPARA	-9572
ACACB	-9522
FASN	-9192
SQLE	-9083
MTF1	-8251
PMVK	-7938
MED1	-7048
GGPS1	-6842
ACACA	-6054
HELZ2	-5553
DHCR7	-4749
CYP51A1	-4187
SCD	-4167
TGS1	-3371
NFYA	-3268
CHD9	-2377
NCOA2	-2061
TBL1XR1	-1268
NFYC	-1144
MVK	-1076
FDPS	-955
HMGCR	-848
NCOA6	-687
FDFT1	-19
NFYB	1122
SC5D	1224
SMARCD3	1713
TM7SF2	2578
NCOA1	2647
ELOVL6	3026
IDI1	4847
SP1	5167
GPAM	8224

---

REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

	778
set	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS
setSize	30
pANOVA	0.00455
s.dist	0.299
p.adjustANOVA	0.174

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SCN11A	8385
SCN2A	8302
NRCAM	6666
SCN3A	6640
ACTB	6120
SCN1A	6002
NFASC	5911
SCN2B	5724
SPTBN2	5686
KCNQ3	5634
SCN7A	4342
SCN9A	4195
ANK1	3694
ACTG1	2573
SPTBN5	2404
SCN3B	2019
ANK2	1944
SCN5A	1522
SCN4B	1272
SPTA1	1100

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SCN11A	8385
SCN2A	8302
NRCAM	6666
SCN3A	6640
ACTB	6120
SCN1A	6002
NFASC	5911
SCN2B	5724
SPTBN2	5686
KCNQ3	5634
SCN7A	4342
SCN9A	4195
ANK1	3694
ACTG1	2573
SPTBN5	2404
SCN3B	2019
ANK2	1944
SCN5A	1522
SCN4B	1272
SPTA1	1100
SCN10A	924
SPTB	606
SPTBN4	74
SPTBN1	-1621
SCN8A	-1949
ANK3	-2306
KCNQ2	-3130
SPTAN1	-4822
SCN1B	-5938
SCN4A	-7372

---

REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

	1284
set	REACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN
setSize	37
pANOVA	0.00517
s.dist	-0.266
p.adjustANOVA	0.193

Top enriched genes

Top 20 genes

GeneID	Gene Rank
SMARCD1	-9904
SMARCA4	-9645
HIPK2	-9492
CSNK2A2	-9451
CBX6	-9132
PHC2	-8971
YAF2	-8339
ARID1A	-8158
SMARCC2	-7750
RING1	-7616
ARID1B	-7237
RYBP	-7073
CBFB	-6906
SMARCE1	-6519
PBRM1	-6498
ARID2	-6441
CSNK2A1	-5317
CBX8	-4711
SMARCD2	-4160
ACTL6B	-3773

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
SMARCD1	-9904
SMARCA4	-9645
HIPK2	-9492
CSNK2A2	-9451
CBX6	-9132
PHC2	-8971
YAF2	-8339
ARID1A	-8158
SMARCC2	-7750
RING1	-7616
ARID1B	-7237
RYBP	-7073
CBFB	-6906
SMARCE1	-6519
PBRM1	-6498
ARID2	-6441
CSNK2A1	-5317
CBX8	-4711
SMARCD2	-4160
ACTL6B	-3773
CBX2	-3745
EP300	-3709
SMARCC1	-3694
PHC3	-3311
RUNX1	-3102
SMARCA2	-3060
PCGF5	-2493
AUTS2	-1412
PHC1	-905
ACTL6A	666
SMARCD3	1713
CSNK2B	1887
CBX4	2250
BMI1	2773
RNF2	3188
SCMH1	3791
SMARCB1	6293

---

REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

	428
set	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE
setSize	63
pANOVA	0.00565
s.dist	0.202
p.adjustANOVA	0.206

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CYP8B1	9720.0
CYP4A22	9719.0
CYP2C19	9615.0
CYP3A5	9543.5
CYP2A13	9441.0
CYP2C9	9440.0
CYP11B2	9391.0
CYP4F12	9276.0
CYP3A4	8758.0
CYP2C18	8687.0
CYP2B6	8597.0
CYP2C8	8325.0
CYP46A1	7934.0
CYP1A1	7913.0
CYP7A1	7716.0
CYP4A11	7433.0
CYP7B1	7142.0
CYP26A1	6706.0
CYP4F11	6534.0
CYP24A1	5882.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CYP8B1	9720.0
CYP4A22	9719.0
CYP2C19	9615.0
CYP3A5	9543.5
CYP2A13	9441.0
CYP2C9	9440.0
CYP11B2	9391.0
CYP4F12	9276.0
CYP3A4	8758.0
CYP2C18	8687.0
CYP2B6	8597.0
CYP2C8	8325.0
CYP46A1	7934.0
CYP1A1	7913.0
CYP7A1	7716.0
CYP4A11	7433.0
CYP7B1	7142.0
CYP26A1	6706.0
CYP4F11	6534.0
CYP24A1	5882.0
POMC	5282.0
FDXR	5229.0
ARNT2	4944.0
PTGIS	4753.0
CYP19A1	4396.0
NR1H4	3110.0
TBXAS1	2937.0
CYP2J2	2860.0
CYP2W1	2847.0
NCOA1	2647.0
CYP2R1	2532.0
CYP39A1	1752.0
AHR	1457.0
CYP2A7	1080.0
CYP2E1	676.0
CYP2F1	408.0
CYP1B1	231.0
CYP3A7	-1097.0
CYP4B1	-1264.0
ARNT	-1688.0
NCOA2	-2061.0
CYP2U1	-2364.0
CYP27A1	-2491.0
CYP1A2	-3364.0
CYP3A43	-3464.0
FDX1	-3548.0
CYP26B1	-3923.0
CYP51A1	-4187.0
CYP2D6	-4218.0
CYP2S1	-4351.0
CYP4F8	-4420.0
CYP4V2	-4577.0
CYP4F22	-5893.0
CYP26C1	-5908.0
CYP27B1	-8437.0
CYP4F3	-8655.0
FDX2	-9111.0
CYP4F2	-9208.0
CYP11A1	-9504.0
RXRA	-10375.0
CYP11B1	-10709.0
POR	-10855.0
CYP21A2	-11410.0

---

REACTOME_BIOLOGICAL_OXIDATIONS

REACTOME_BIOLOGICAL_OXIDATIONS

	427
set	REACTOME_BIOLOGICAL_OXIDATIONS
setSize	210
pANOVA	0.00596
s.dist	0.11
p.adjustANOVA	0.208

Top enriched genes

Top 20 genes

GeneID	Gene Rank
GSTA2	9816.0
CYP8B1	9720.0
CYP4A22	9719.0
CYP2C19	9615.0
ADH1A	9596.0
GSTA1	9554.0
CYP3A5	9543.5
ACSM4	9534.0
CYP2A13	9441.0
CYP2C9	9440.0
CYP11B2	9391.0
CYP4F12	9276.0
NNMT	9150.0
ACSM2A	9029.0
ADH1C	8760.0
CYP3A4	8758.0
CYP2C18	8687.0
SULT1A1	8614.0
CYP2B6	8597.0
SLC35B3	8572.0

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
GSTA2	9816.0
CYP8B1	9720.0
CYP4A22	9719.0
CYP2C19	9615.0
ADH1A	9596.0
GSTA1	9554.0
CYP3A5	9543.5
ACSM4	9534.0
CYP2A13	9441.0
CYP2C9	9440.0
CYP11B2	9391.0
CYP4F12	9276.0
NNMT	9150.0
ACSM2A	9029.0
ADH1C	8760.0
CYP3A4	8758.0
CYP2C18	8687.0
SULT1A1	8614.0
CYP2B6	8597.0
SLC35B3	8572.0
SULT1C2	8427.0
NAT2	8421.0
CYP2C8	8325.0
AOC3	8290.0
CYP46A1	7934.0
UGT2B7	7929.0
CYP1A1	7913.0
CYP7A1	7716.0
GSTA5	7436.0
CYP4A11	7433.0
GLYATL3	7263.0
MAT1A	7191.0
CYP7B1	7142.0
FMO3	7127.0
GLYAT	7053.0
BPNT1	6941.0
UGT2B4	6754.0
UGT2B11	6737.0
CYP26A1	6706.0
GLYATL1	6659.0
DPEP3	6636.0
CYP4F11	6534.0
UGT1A3	6311.0
CYP24A1	5882.0
UGT1A10	5546.0
UGT1A8	5490.0
UGT1A7	5370.0
POMC	5282.0
ADH1B	5245.0
FDXR	5229.0
UGT1A9	5210.0
CYB5B	5196.0
UGT2B15	5178.0
FMO2	5008.0
GSTO2	4961.0
ARNT2	4944.0
SULT1E1	4912.0
GSTM3	4893.0
PTGIS	4753.0
UGT1A4	4750.0
GSTO1	4729.0
SULT2B1	4517.0
GSTA3	4468.0
CYP19A1	4396.0
BPHL	4381.0
UGT1A6	4015.0
ADH6	3880.0
GSTM4	3688.0
SULT2A1	3679.0
AIP	3521.0
UGT2A1	3483.0
SULT1B1	3427.0
ADH4	3320.0
AKR7A3	3296.0
UGT3A1	3215.0
GSTA4	3183.0
DPEP2	3140.0
NR1H4	3110.0
TBXAS1	2937.0
UGT1A5	2913.0
CYP2J2	2860.0
CYP2W1	2847.0
PTGES3	2667.0
NCOA1	2647.0
MGST3	2632.0
UGT2A2	2619.0
CYP2R1	2532.0
CES2	2397.0
ABHD14B	2355.0
HSP90AB1	2253.0
CBR3	2150.0
UGT1A1	2139.0
ALDH1B1	1904.0
GSS	1873.0
AHCY	1866.0
CYP39A1	1752.0
ACSM5	1529.0
AHR	1457.0
TRMT112	1430.0
FMO1	1199.0
CYP2A7	1080.0
MAT2B	968.0
ABHD10	850.0
GGCT	759.0
CYP2E1	676.0
MTARC1	643.0
CYP2F1	408.0
ALDH2	339.0
CYP1B1	231.0
GCLC	-25.0
ACY3	-95.0
AKR1A1	-111.0
PAOX	-216.0
UGT3A2	-275.0
NQO2	-345.0
PAPSS2	-412.0
CES1	-660.0
OPLAH	-752.0
ALDH3A1	-871.0
ACSM1	-980.0
CYP3A7	-1097.0
CYP4B1	-1264.0
SLC35D1	-1446.0
CES3	-1599.0
AS3MT	-1658.0
CHAC1	-1664.0
ARNT	-1688.0
SULT1C4	-1706.0
SLC35B2	-1887.0
CMBL	-2014.0
NCOA2	-2061.0
AADAC	-2173.0
CYP2U1	-2364.0
CYP27A1	-2491.0
GGT6	-2799.0
SULT4A1	-2938.0
ESD	-2949.0
N6AMT1	-3015.0
GSTZ1	-3122.0
CYP1A2	-3364.0
MAT2A	-3447.0
NAT1	-3453.0
CYP3A43	-3464.0
FDX1	-3548.0
CHAC2	-3557.0
PODXL2	-3629.0
UGP2	-3801.0
MTARC2	-3896.0
CYP26B1	-3923.0
SMOX	-3945.0
ACY1	-3978.0
CYP51A1	-4187.0
CYP2D6	-4218.0
TPMT	-4346.0
CYP2S1	-4351.0
CYP4F8	-4420.0
CYP4V2	-4577.0
GSTP1	-4595.0
UGT2A3	-4607.0
MTRR	-4722.0
ALDH1A1	-4855.0
ADH7	-4862.0
SLC26A2	-5234.0
CNDP2	-5276.0
HPGDS	-5458.0
TPST1	-5669.0
CYP4F22	-5893.0
CYP26C1	-5908.0
SLC26A1	-6182.0
GSTK1	-6350.0
AOC1	-6367.0
PTGS1	-6919.0
GCLM	-6979.0
GSTM1	-7009.0
AKR7L	-7166.0
ACSS1	-7450.0
MTR	-7507.0
PAPSS1	-7510.0
SULT6B1	-7649.0
ACSS2	-7774.0
GSTM5	-8095.0
SULT1A2	-8281.0
CYP27B1	-8437.0
CYP4F3	-8655.0
GLYATL2	-8693.0
UGT2B17	-8880.0
BPNT2	-8946.0
DPEP1	-9087.0
FDX2	-9111.0
CYP4F2	-9208.0
GGT1	-9308.0
UGDH	-9336.0
MGST2	-9427.0
CYP11A1	-9504.0
ADH5	-9648.0
EPHX1	-9874.0
AOC2	-9915.0
GGT5	-10147.0
GGT7	-10212.0
ACSM2B	-10230.0
RXRA	-10375.0
MGST1	-10399.0
AKR7A2	-10496.0
CYP11B1	-10709.0
COMT	-10768.0
POR	-10855.0
TPST2	-10966.0
CYB5R3	-11017.0
CYP21A2	-11410.0
GSTM2	-11564.0

---

REACTOME_ATORVASTATIN_ADME

REACTOME_ATORVASTATIN_ADME

	1602
set	REACTOME_ATORVASTATIN_ADME
setSize	9
pANOVA	0.00596
s.dist	0.529
p.adjustANOVA	0.208

Top enriched genes

Top 20 genes

GeneID	Gene Rank
PON1	9209
CYP3A4	8758
SLCO1B1	6349
UGT1A3	6311
SLCO1B3	6125
PON3	5337
ABCC2	5010
ABCB1	-1047
SLCO2B1	-3865

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
PON1	9209
CYP3A4	8758
SLCO1B1	6349
UGT1A3	6311
SLCO1B3	6125
PON3	5337
ABCC2	5010
ABCB1	-1047
SLCO2B1	-3865

---

REACTOME_PTK6_REGULATES_RHO_GTPASES_RAS_GTPASE_AND_MAP_KINASES

REACTOME_PTK6_REGULATES_RHO_GTPASES_RAS_GTPASE_AND_MAP_KINASES

	1224
set	REACTOME_PTK6_REGULATES_RHO_GTPASES_RAS_GTPASE_AND_MAP_KINASES
setSize	14
pANOVA	0.00668
s.dist	-0.419
p.adjustANOVA	0.227

Top enriched genes

Top 20 genes

GeneID	Gene Rank
RHOA	-10972
HRAS	-10751
NRAS	-9345
PXN	-8993
PTK6	-8366
KRAS	-7903
ELMO1	-6023
RAC1	-5471
ELMO2	-5259
RASA1	-3259
CRK	-2873
DOCK1	-1837
ARHGAP35	-669
BCAR1	1380

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
RHOA	-10972
HRAS	-10751
NRAS	-9345
PXN	-8993
PTK6	-8366
KRAS	-7903
ELMO1	-6023
RAC1	-5471
ELMO2	-5259
RASA1	-3259
CRK	-2873
DOCK1	-1837
ARHGAP35	-669
BCAR1	1380

---

REACTOME_PD_1_SIGNALING

REACTOME_PD_1_SIGNALING

	646
set	REACTOME_PD_1_SIGNALING
setSize	21
pANOVA	0.00676
s.dist	0.341
p.adjustANOVA	0.227

Top enriched genes

Top 20 genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
LCK	9316
PDCD1	8558
HLA-DRA	8538
HLA-DPB1	6475
CD247	5640
HLA-DQA1	4376
HLA-DRB5	3407
CSK	3354
HLA-DQA2	2476
CD274	1700
HLA-DRB1	520
HLA-DQB2	507
PDCD1LG2	-1401
PTPN6	-2123
HLA-DQB1	-3560
PTPN11	-4589
HLA-DPA1	-7387

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
CD3D	9867
CD3G	9855
CD3E	9809
LCK	9316
PDCD1	8558
HLA-DRA	8538
HLA-DPB1	6475
CD247	5640
HLA-DQA1	4376
HLA-DRB5	3407
CSK	3354
HLA-DQA2	2476
CD274	1700
HLA-DRB1	520
HLA-DQB2	507
PDCD1LG2	-1401
PTPN6	-2123
HLA-DQB1	-3560
PTPN11	-4589
HLA-DPA1	-7387
CD4	-10366

---

REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

	1633
set	REACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES
setSize	7
pANOVA	0.00711
s.dist	-0.587
p.adjustANOVA	0.229

Top enriched genes

Top 20 genes

GeneID	Gene Rank
TALDO1	-11147
PGD	-10774
CREBBP	-9764
TKT	-8511
MAFG	-4954
NFE2L2	-4319
EP300	-3709

Click HERE to show all gene set members

All member genes

GeneID	Gene Rank
TALDO1	-11147
PGD	-10774
CREBBP	-9764
TKT	-8511
MAFG	-4954
NFE2L2	-4319
EP300	-3709

---

Here is the session info with all the versions of packages used.

sessionInfo()

## R version 4.3.2 (2023-10-31)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 22.04.3 LTS
## 
## Matrix products: default
## BLAS:   /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3 
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/libopenblasp-r0.3.20.so;  LAPACK version 3.10.0
## 
## locale:
##  [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
##  [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
##  [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
##  [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
##  [9] LC_ADDRESS=C               LC_TELEPHONE=C            
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
## 
## time zone: Etc/UTC
## tzcode source: system (glibc)
## 
## attached base packages:
## [1] parallel  stats4    stats     graphics  grDevices utils     datasets 
## [8] methods   base     
## 
## other attached packages:
##  [1] pkgload_1.3.3                                      
##  [2] GGally_2.2.0                                       
##  [3] ggplot2_3.4.4                                      
##  [4] reshape2_1.4.4                                     
##  [5] gtools_3.9.5                                       
##  [6] tibble_3.2.1                                       
##  [7] dplyr_1.1.4                                        
##  [8] echarts4r_0.4.5                                    
##  [9] png_0.1-8                                          
## [10] gridExtra_2.3                                      
## [11] missMethyl_1.36.0                                  
## [12] IlluminaHumanMethylation450kanno.ilmn12.hg19_0.6.1 
## [13] beeswarm_0.4.0                                     
## [14] kableExtra_1.3.4                                   
## [15] gplots_3.1.3                                       
## [16] mitch_1.15.0                                       
## [17] tictoc_1.2                                         
## [18] HGNChelper_0.8.1                                   
## [19] IlluminaHumanMethylationEPICanno.ilm10b4.hg19_0.6.0
## [20] IlluminaHumanMethylation450kmanifest_0.4.0         
## [21] minfi_1.48.0                                       
## [22] bumphunter_1.44.0                                  
## [23] locfit_1.5-9.8                                     
## [24] iterators_1.0.14                                   
## [25] foreach_1.5.2                                      
## [26] Biostrings_2.70.1                                  
## [27] XVector_0.42.0                                     
## [28] SummarizedExperiment_1.32.0                        
## [29] Biobase_2.62.0                                     
## [30] MatrixGenerics_1.14.0                              
## [31] matrixStats_1.2.0                                  
## [32] GenomicRanges_1.54.1                               
## [33] GenomeInfoDb_1.38.2                                
## [34] IRanges_2.36.0                                     
## [35] S4Vectors_0.40.2                                   
## [36] BiocGenerics_0.48.1                                
## [37] eulerr_7.0.0                                       
## [38] limma_3.58.1                                       
## 
## loaded via a namespace (and not attached):
##   [1] splines_4.3.2             later_1.3.2              
##   [3] BiocIO_1.12.0             bitops_1.0-7             
##   [5] filelock_1.0.3            preprocessCore_1.64.0    
##   [7] XML_3.99-0.16             lifecycle_1.0.4          
##   [9] lattice_0.22-5            MASS_7.3-60              
##  [11] base64_2.0.1              scrime_1.3.5             
##  [13] magrittr_2.0.3            sass_0.4.8               
##  [15] rmarkdown_2.25            jquerylib_0.1.4          
##  [17] yaml_2.3.8                httpuv_1.6.13            
##  [19] doRNG_1.8.6               askpass_1.2.0            
##  [21] DBI_1.1.3                 RColorBrewer_1.1-3       
##  [23] abind_1.4-5               zlibbioc_1.48.0          
##  [25] rvest_1.0.3               quadprog_1.5-8           
##  [27] purrr_1.0.2               RCurl_1.98-1.13          
##  [29] rappdirs_0.3.3            GenomeInfoDbData_1.2.11  
##  [31] genefilter_1.84.0         annotate_1.80.0          
##  [33] svglite_2.1.3             DelayedMatrixStats_1.24.0
##  [35] codetools_0.2-19          DelayedArray_0.28.0      
##  [37] xml2_1.3.6                tidyselect_1.2.0         
##  [39] beanplot_1.3.1            BiocFileCache_2.10.1     
##  [41] webshot_0.5.5             illuminaio_0.44.0        
##  [43] GenomicAlignments_1.38.0  jsonlite_1.8.8           
##  [45] multtest_2.58.0           ellipsis_0.3.2           
##  [47] survival_3.5-7            systemfonts_1.0.5        
##  [49] tools_4.3.2               progress_1.2.3           
##  [51] Rcpp_1.0.11               glue_1.6.2               
##  [53] SparseArray_1.2.2         xfun_0.41                
##  [55] HDF5Array_1.30.0          withr_2.5.2              
##  [57] fastmap_1.1.1             rhdf5filters_1.14.1      
##  [59] fansi_1.0.6               openssl_2.1.1            
##  [61] caTools_1.18.2            digest_0.6.33            
##  [63] R6_2.5.1                  mime_0.12                
##  [65] colorspace_2.1-0          biomaRt_2.58.0           
##  [67] RSQLite_2.3.4             utf8_1.2.4               
##  [69] tidyr_1.3.0               generics_0.1.3           
##  [71] data.table_1.14.10        rtracklayer_1.62.0       
##  [73] prettyunits_1.2.0         httr_1.4.7               
##  [75] htmlwidgets_1.6.4         S4Arrays_1.2.0           
##  [77] ggstats_0.5.1             pkgconfig_2.0.3          
##  [79] gtable_0.3.4              blob_1.2.4               
##  [81] siggenes_1.76.0           htmltools_0.5.7          
##  [83] scales_1.3.0              rstudioapi_0.15.0        
##  [85] knitr_1.45                tzdb_0.4.0               
##  [87] rjson_0.2.21              nlme_3.1-163             
##  [89] curl_5.2.0                org.Hs.eg.db_3.18.0      
##  [91] cachem_1.0.8              rhdf5_2.46.1             
##  [93] stringr_1.5.1             KernSmooth_2.23-22       
##  [95] AnnotationDbi_1.64.1      restfulr_0.0.15          
##  [97] GEOquery_2.70.0           pillar_1.9.0             
##  [99] grid_4.3.2                reshape_0.8.9            
## [101] vctrs_0.6.5               promises_1.2.1           
## [103] dbplyr_2.4.0              xtable_1.8-4             
## [105] evaluate_0.23             readr_2.1.4              
## [107] GenomicFeatures_1.54.1    cli_3.6.2                
## [109] compiler_4.3.2            Rsamtools_2.18.0         
## [111] rlang_1.1.2               crayon_1.5.2             
## [113] rngtools_1.5.2            nor1mix_1.3-2            
## [115] mclust_6.0.1              plyr_1.8.9               
## [117] stringi_1.8.3             viridisLite_0.4.2        
## [119] BiocParallel_1.36.0       munsell_0.5.0            
## [121] Matrix_1.6-1.1            hms_1.1.3                
## [123] sparseMatrixStats_1.14.0  bit64_4.0.5              
## [125] Rhdf5lib_1.24.1           KEGGREST_1.42.0          
## [127] statmod_1.5.0             shiny_1.8.0              
## [129] highr_0.10                memoise_2.0.1            
## [131] bslib_0.6.1               bit_4.0.5

END of report