Mitch Report
Antony Kaspi & Mark Ziemann
date generated: 2021-10-11
Background
Mitch performs unidimensional and multidimensional gene set enrichment analysis. The concept behind this dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12). This implementation is suited to R based workflows of multi-omics datasets. This software was developed by Antony Kaspi and Mark Ziemann. Learn more about Mitch at the website: https://github.com/markziemann/Mitch
Input profiles
Here is the first few lines of the input profile.
## diab PMX
## 0610006L08Rik -5.5412223 1.7043723
## 0610007P14Rik -0.5043192 0.5154128
## 0610009B22Rik -1.1468556 0.7601283
## 0610009E02Rik -1.0617246 0.7364015
## 0610009L18Rik -3.4134523 2.9613348
## 0610009O20Rik -1.1413048 1.7889029| Profile metrics | |
|---|---|
| num_genes_in_profile | 28178 |
| duplicated_genes_present | 0 |
| num_profile_genes_in_sets | 1392 |
| num_profile_genes_not_in_sets | 26786 |
| profile_pearson_correl | -0.74519 |
| profile_spearman_correl | -0.68447 |
Here is a plot of the input profiles. Note the dynamic ranges. 
Here is the contour plot of the profile including all detected genes. 
Input genesets
Here are some metrics about the gene sets used: GMT file of genesets:| Gene sets metrics | |
|---|---|
| num_genesets | 76 |
| num_genesets_excluded | 30 |
| num_genesets_included | 46 |
Gene sets by quadrant
Number of significant gene sets (FDR<0.05)= 10 
Interactive enrichment scatterplot
All sets with FDR<0.05. Try hovering over the points.
Top N sets irrespective of FDR. Try hovering over the points.
A heatmap of S values for top results
A plot of effect size versus significance
Significance is the -log2(p.adjustMANOVA) and effect size is the s.dist which is the hypotenuse of the s scores.
Results table
Top N= 46 gene sets| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.diab | s.PMX | p.diab | p.PMX |
|---|---|---|---|---|---|---|---|---|
| Downstream-signaling-events-of-B-Cell-Receptor-(BCR) | 79 | 3.30e-06 | 0.000152 | 0.27300 | 0.04770 | -0.26800 | 4.63e-01 | 3.70e-05 |
| Cell-Cycle-Checkpoints | 249 | 1.04e-05 | 0.000238 | 0.22700 | 0.15300 | -0.16800 | 3.01e-05 | 4.81e-06 |
| APC:Cdc20-mediated-degradation-of-cell-cycle-proteins-prior-to-satisfation-of-the-cell-cycle-checkpoint | 71 | 3.41e-05 | 0.000523 | 0.33700 | 0.15000 | -0.30100 | 2.85e-02 | 1.11e-05 |
| APC/C-mediated-degradation-of-cell-cycle-proteins | 85 | 6.82e-05 | 0.000628 | 0.31000 | 0.15200 | -0.27100 | 1.56e-02 | 1.57e-05 |
| Regulation-of-mitotic-cell-cycle | 85 | 6.82e-05 | 0.000628 | 0.31000 | 0.15200 | -0.27100 | 1.56e-02 | 1.57e-05 |
| Cell-Cycle,-Mitotic | 479 | 9.44e-05 | 0.000724 | 0.14200 | 0.11400 | -0.08490 | 1.78e-05 | 1.41e-03 |
| Cell-Cycle | 603 | 1.23e-04 | 0.000811 | 0.12300 | 0.10100 | -0.07100 | 2.22e-05 | 2.83e-03 |
| Integrin-cell-surface-interactions | 64 | 7.60e-04 | 0.004370 | 0.25100 | -0.06970 | 0.24100 | 3.35e-01 | 8.62e-04 |
| Signaling-by-the-B-Cell-Receptor-(BCR) | 120 | 2.66e-03 | 0.013600 | 0.10200 | -0.06580 | -0.07850 | 2.13e-01 | 1.37e-01 |
| Antigen-activates-B-Cell-Receptor-(BCR)-leading-to-generation-of-second-messengers | 42 | 4.05e-03 | 0.018600 | 0.38300 | -0.27900 | 0.26300 | 1.74e-03 | 3.22e-03 |
| Senescence-Associated-Secretory-Phenotype-(SASP) | 48 | 2.29e-02 | 0.096000 | 0.29100 | 0.22500 | -0.18500 | 6.93e-03 | 2.65e-02 |
| Cell-surface-interactions-at-the-vascular-wall | 126 | 3.05e-02 | 0.117000 | 0.11200 | -0.01840 | 0.11100 | 7.22e-01 | 3.14e-02 |
| TP53-Regulates-Transcription-of-Genes-Involved-in-G2-Cell-Cycle-Arrest | 18 | 3.47e-02 | 0.123000 | 0.33100 | 0.31500 | -0.10000 | 2.06e-02 | 4.63e-01 |
| TP53-Regulates-Transcription-of-Cell-Cycle-Genes | 46 | 4.69e-02 | 0.154000 | 0.21700 | 0.19900 | -0.08560 | 1.95e-02 | 3.15e-01 |
| Regulation-of-necroptotic-cell-death | 26 | 5.72e-02 | 0.166000 | 0.29500 | 0.13300 | -0.26300 | 2.42e-01 | 2.02e-02 |
| Apoptotic-cleavage-of-cell-adhesion–proteins | 10 | 6.09e-02 | 0.166000 | 0.34600 | 0.34300 | -0.04410 | 6.00e-02 | 8.09e-01 |
| ERBB2-Regulates-Cell-Motility | 14 | 6.13e-02 | 0.166000 | 0.32500 | 0.08050 | -0.31400 | 6.02e-01 | 4.16e-02 |
| Aberrant-regulation-of-mitotic-cell-cycle-due-to-RB1-defects | 36 | 7.21e-02 | 0.182000 | 0.24700 | 0.21700 | -0.11900 | 2.42e-02 | 2.17e-01 |
| Diseases-of-mitotic-cell-cycle | 38 | 7.53e-02 | 0.182000 | 0.24100 | 0.21000 | -0.11800 | 2.49e-02 | 2.08e-01 |
| Nef-mediates-down-modulation-of-cell-surface-receptors-by-recruiting-them-to-clathrin-adapters | 20 | 8.70e-02 | 0.200000 | 0.18900 | 0.03000 | 0.18600 | 8.17e-01 | 1.49e-01 |
| Assembly-and-cell-surface-presentation-of-NMDA-receptors | 25 | 9.83e-02 | 0.215000 | 0.14300 | 0.12200 | 0.07460 | 2.91e-01 | 5.18e-01 |
| Regulation-of-beta-cell-development | 35 | 1.04e-01 | 0.217000 | 0.26700 | -0.20100 | 0.17500 | 3.91e-02 | 7.25e-02 |
| Programmed-Cell-Death | 185 | 1.24e-01 | 0.247000 | 0.11000 | 0.06830 | -0.08610 | 1.09e-01 | 4.31e-02 |
| Sema4D-induced-cell-migration-and-growth-cone-collapse | 19 | 1.52e-01 | 0.292000 | 0.21400 | 0.21100 | -0.03740 | 1.11e-01 | 7.78e-01 |
| Cell-Cell-communication | 110 | 2.02e-01 | 0.361000 | 0.08630 | 0.08400 | -0.01970 | 1.28e-01 | 7.21e-01 |
| Cell-extracellular-matrix-interactions | 16 | 2.04e-01 | 0.361000 | 0.15000 | -0.13200 | -0.07030 | 3.59e-01 | 6.27e-01 |
| Cell-junction-organization | 78 | 2.17e-01 | 0.369000 | 0.14100 | 0.11400 | -0.08300 | 8.08e-02 | 2.05e-01 |
| MET-promotes-cell-motility | 29 | 2.30e-01 | 0.378000 | 0.18600 | -0.07010 | 0.17200 | 5.13e-01 | 1.09e-01 |
| FOXO-mediated-transcription-of-cell-cycle-genes | 15 | 2.62e-01 | 0.416000 | 0.31400 | 0.23600 | -0.20700 | 1.14e-01 | 1.65e-01 |
| Cell-cell-junction-organization | 53 | 2.74e-01 | 0.416000 | 0.09720 | 0.09700 | -0.00576 | 2.22e-01 | 9.42e-01 |
| VEGFR2-mediated-cell-proliferation | 19 | 2.81e-01 | 0.416000 | 0.23200 | 0.20600 | -0.10700 | 1.20e-01 | 4.20e-01 |
| TP53-Regulates-Transcription-of-Genes-Involved-in-G1-Cell-Cycle-Arrest | 13 | 3.67e-01 | 0.527000 | 0.24400 | 0.21900 | -0.10700 | 1.71e-01 | 5.02e-01 |
| NRIF-signals-cell-death-from-the-nucleus | 15 | 4.66e-01 | 0.650000 | 0.22100 | 0.12200 | -0.18400 | 4.13e-01 | 2.17e-01 |
| Cell-death-signalling-via-NRAGE,-NRIF-and-NADE | 73 | 5.41e-01 | 0.732000 | 0.04960 | 0.04900 | 0.00785 | 4.69e-01 | 9.08e-01 |
| FOXO-mediated-transcription-of-cell-death-genes | 15 | 7.17e-01 | 0.920000 | 0.15100 | -0.09070 | 0.12100 | 5.43e-01 | 4.17e-01 |
| Oncogene-Induced-Senescence | 31 | 7.36e-01 | 0.920000 | 0.05040 | -0.01480 | -0.04810 | 8.86e-01 | 6.43e-01 |
| Formation-of-Senescence-Associated-Heterochromatin-Foci-(SAHF) | 11 | 7.47e-01 | 0.920000 | 0.15200 | -0.07560 | 0.13200 | 6.64e-01 | 4.50e-01 |
| DNA-Damage/Telomere-Stress-Induced-Senescence | 28 | 7.74e-01 | 0.920000 | 0.05060 | 0.00999 | 0.04960 | 9.27e-01 | 6.49e-01 |
| Oxidative-Stress-Induced-Senescence | 62 | 7.86e-01 | 0.920000 | 0.05400 | -0.04890 | 0.02290 | 5.06e-01 | 7.55e-01 |
| Diseases-of-programmed-cell-death | 42 | 8.00e-01 | 0.920000 | 0.04360 | -0.04360 | 0.00020 | 6.25e-01 | 9.98e-01 |
| TP53-Regulates-Transcription-of-Cell-Death-Genes | 37 | 8.40e-01 | 0.943000 | 0.03730 | 0.00550 | 0.03690 | 9.54e-01 | 6.98e-01 |
| TP53-regulates-transcription-of-several-additional-cell-death-genes-whose-specific-roles-in-p53-dependent-apoptosis-remain-uncertain | 13 | 8.64e-01 | 0.946000 | 0.11200 | 0.07680 | -0.08170 | 6.32e-01 | 6.10e-01 |
| Cell-recruitment-(pro-inflammatory-response) | 24 | 9.00e-01 | 0.954000 | 0.06930 | -0.04450 | 0.05300 | 7.06e-01 | 6.53e-01 |
| TP53-regulates-transcription-of-additional-cell-cycle-genes-whose-exact-role-in-the-p53-pathway-remain-uncertain | 19 | 9.33e-01 | 0.954000 | 0.06210 | 0.04880 | -0.03840 | 7.13e-01 | 7.72e-01 |
| EGR2-and-SOX10-mediated-initiation-of-Schwann-cell-myelination | 27 | 9.34e-01 | 0.954000 | 0.04460 | -0.03980 | 0.02020 | 7.20e-01 | 8.56e-01 |
| Cellular-Senescence | 124 | 9.54e-01 | 0.954000 | 0.00952 | -0.00377 | -0.00874 | 9.42e-01 | 8.66e-01 |
Results (complete table)
Click HERE to show results for all gene sets
| set | setSize | pMANOVA | p.adjustMANOVA | s.dist | s.diab | s.PMX | p.diab | p.PMX |
|---|---|---|---|---|---|---|---|---|
| Downstream-signaling-events-of-B-Cell-Receptor-(BCR) | 79 | 3.30e-06 | 0.000152 | 0.27300 | 0.04770 | -0.26800 | 4.63e-01 | 3.70e-05 |
| Cell-Cycle-Checkpoints | 249 | 1.04e-05 | 0.000238 | 0.22700 | 0.15300 | -0.16800 | 3.01e-05 | 4.81e-06 |
| APC:Cdc20-mediated-degradation-of-cell-cycle-proteins-prior-to-satisfation-of-the-cell-cycle-checkpoint | 71 | 3.41e-05 | 0.000523 | 0.33700 | 0.15000 | -0.30100 | 2.85e-02 | 1.11e-05 |
| APC/C-mediated-degradation-of-cell-cycle-proteins | 85 | 6.82e-05 | 0.000628 | 0.31000 | 0.15200 | -0.27100 | 1.56e-02 | 1.57e-05 |
| Regulation-of-mitotic-cell-cycle | 85 | 6.82e-05 | 0.000628 | 0.31000 | 0.15200 | -0.27100 | 1.56e-02 | 1.57e-05 |
| Cell-Cycle,-Mitotic | 479 | 9.44e-05 | 0.000724 | 0.14200 | 0.11400 | -0.08490 | 1.78e-05 | 1.41e-03 |
| Cell-Cycle | 603 | 1.23e-04 | 0.000811 | 0.12300 | 0.10100 | -0.07100 | 2.22e-05 | 2.83e-03 |
| Integrin-cell-surface-interactions | 64 | 7.60e-04 | 0.004370 | 0.25100 | -0.06970 | 0.24100 | 3.35e-01 | 8.62e-04 |
| Signaling-by-the-B-Cell-Receptor-(BCR) | 120 | 2.66e-03 | 0.013600 | 0.10200 | -0.06580 | -0.07850 | 2.13e-01 | 1.37e-01 |
| Antigen-activates-B-Cell-Receptor-(BCR)-leading-to-generation-of-second-messengers | 42 | 4.05e-03 | 0.018600 | 0.38300 | -0.27900 | 0.26300 | 1.74e-03 | 3.22e-03 |
| Senescence-Associated-Secretory-Phenotype-(SASP) | 48 | 2.29e-02 | 0.096000 | 0.29100 | 0.22500 | -0.18500 | 6.93e-03 | 2.65e-02 |
| Cell-surface-interactions-at-the-vascular-wall | 126 | 3.05e-02 | 0.117000 | 0.11200 | -0.01840 | 0.11100 | 7.22e-01 | 3.14e-02 |
| TP53-Regulates-Transcription-of-Genes-Involved-in-G2-Cell-Cycle-Arrest | 18 | 3.47e-02 | 0.123000 | 0.33100 | 0.31500 | -0.10000 | 2.06e-02 | 4.63e-01 |
| TP53-Regulates-Transcription-of-Cell-Cycle-Genes | 46 | 4.69e-02 | 0.154000 | 0.21700 | 0.19900 | -0.08560 | 1.95e-02 | 3.15e-01 |
| Regulation-of-necroptotic-cell-death | 26 | 5.72e-02 | 0.166000 | 0.29500 | 0.13300 | -0.26300 | 2.42e-01 | 2.02e-02 |
| Apoptotic-cleavage-of-cell-adhesion–proteins | 10 | 6.09e-02 | 0.166000 | 0.34600 | 0.34300 | -0.04410 | 6.00e-02 | 8.09e-01 |
| ERBB2-Regulates-Cell-Motility | 14 | 6.13e-02 | 0.166000 | 0.32500 | 0.08050 | -0.31400 | 6.02e-01 | 4.16e-02 |
| Aberrant-regulation-of-mitotic-cell-cycle-due-to-RB1-defects | 36 | 7.21e-02 | 0.182000 | 0.24700 | 0.21700 | -0.11900 | 2.42e-02 | 2.17e-01 |
| Diseases-of-mitotic-cell-cycle | 38 | 7.53e-02 | 0.182000 | 0.24100 | 0.21000 | -0.11800 | 2.49e-02 | 2.08e-01 |
| Nef-mediates-down-modulation-of-cell-surface-receptors-by-recruiting-them-to-clathrin-adapters | 20 | 8.70e-02 | 0.200000 | 0.18900 | 0.03000 | 0.18600 | 8.17e-01 | 1.49e-01 |
| Assembly-and-cell-surface-presentation-of-NMDA-receptors | 25 | 9.83e-02 | 0.215000 | 0.14300 | 0.12200 | 0.07460 | 2.91e-01 | 5.18e-01 |
| Regulation-of-beta-cell-development | 35 | 1.04e-01 | 0.217000 | 0.26700 | -0.20100 | 0.17500 | 3.91e-02 | 7.25e-02 |
| Programmed-Cell-Death | 185 | 1.24e-01 | 0.247000 | 0.11000 | 0.06830 | -0.08610 | 1.09e-01 | 4.31e-02 |
| Sema4D-induced-cell-migration-and-growth-cone-collapse | 19 | 1.52e-01 | 0.292000 | 0.21400 | 0.21100 | -0.03740 | 1.11e-01 | 7.78e-01 |
| Cell-Cell-communication | 110 | 2.02e-01 | 0.361000 | 0.08630 | 0.08400 | -0.01970 | 1.28e-01 | 7.21e-01 |
| Cell-extracellular-matrix-interactions | 16 | 2.04e-01 | 0.361000 | 0.15000 | -0.13200 | -0.07030 | 3.59e-01 | 6.27e-01 |
| Cell-junction-organization | 78 | 2.17e-01 | 0.369000 | 0.14100 | 0.11400 | -0.08300 | 8.08e-02 | 2.05e-01 |
| MET-promotes-cell-motility | 29 | 2.30e-01 | 0.378000 | 0.18600 | -0.07010 | 0.17200 | 5.13e-01 | 1.09e-01 |
| FOXO-mediated-transcription-of-cell-cycle-genes | 15 | 2.62e-01 | 0.416000 | 0.31400 | 0.23600 | -0.20700 | 1.14e-01 | 1.65e-01 |
| Cell-cell-junction-organization | 53 | 2.74e-01 | 0.416000 | 0.09720 | 0.09700 | -0.00576 | 2.22e-01 | 9.42e-01 |
| VEGFR2-mediated-cell-proliferation | 19 | 2.81e-01 | 0.416000 | 0.23200 | 0.20600 | -0.10700 | 1.20e-01 | 4.20e-01 |
| TP53-Regulates-Transcription-of-Genes-Involved-in-G1-Cell-Cycle-Arrest | 13 | 3.67e-01 | 0.527000 | 0.24400 | 0.21900 | -0.10700 | 1.71e-01 | 5.02e-01 |
| NRIF-signals-cell-death-from-the-nucleus | 15 | 4.66e-01 | 0.650000 | 0.22100 | 0.12200 | -0.18400 | 4.13e-01 | 2.17e-01 |
| Cell-death-signalling-via-NRAGE,-NRIF-and-NADE | 73 | 5.41e-01 | 0.732000 | 0.04960 | 0.04900 | 0.00785 | 4.69e-01 | 9.08e-01 |
| FOXO-mediated-transcription-of-cell-death-genes | 15 | 7.17e-01 | 0.920000 | 0.15100 | -0.09070 | 0.12100 | 5.43e-01 | 4.17e-01 |
| Oncogene-Induced-Senescence | 31 | 7.36e-01 | 0.920000 | 0.05040 | -0.01480 | -0.04810 | 8.86e-01 | 6.43e-01 |
| Formation-of-Senescence-Associated-Heterochromatin-Foci-(SAHF) | 11 | 7.47e-01 | 0.920000 | 0.15200 | -0.07560 | 0.13200 | 6.64e-01 | 4.50e-01 |
| DNA-Damage/Telomere-Stress-Induced-Senescence | 28 | 7.74e-01 | 0.920000 | 0.05060 | 0.00999 | 0.04960 | 9.27e-01 | 6.49e-01 |
| Oxidative-Stress-Induced-Senescence | 62 | 7.86e-01 | 0.920000 | 0.05400 | -0.04890 | 0.02290 | 5.06e-01 | 7.55e-01 |
| Diseases-of-programmed-cell-death | 42 | 8.00e-01 | 0.920000 | 0.04360 | -0.04360 | 0.00020 | 6.25e-01 | 9.98e-01 |
| TP53-Regulates-Transcription-of-Cell-Death-Genes | 37 | 8.40e-01 | 0.943000 | 0.03730 | 0.00550 | 0.03690 | 9.54e-01 | 6.98e-01 |
| TP53-regulates-transcription-of-several-additional-cell-death-genes-whose-specific-roles-in-p53-dependent-apoptosis-remain-uncertain | 13 | 8.64e-01 | 0.946000 | 0.11200 | 0.07680 | -0.08170 | 6.32e-01 | 6.10e-01 |
| Cell-recruitment-(pro-inflammatory-response) | 24 | 9.00e-01 | 0.954000 | 0.06930 | -0.04450 | 0.05300 | 7.06e-01 | 6.53e-01 |
| TP53-regulates-transcription-of-additional-cell-cycle-genes-whose-exact-role-in-the-p53-pathway-remain-uncertain | 19 | 9.33e-01 | 0.954000 | 0.06210 | 0.04880 | -0.03840 | 7.13e-01 | 7.72e-01 |
| EGR2-and-SOX10-mediated-initiation-of-Schwann-cell-myelination | 27 | 9.34e-01 | 0.954000 | 0.04460 | -0.03980 | 0.02020 | 7.20e-01 | 8.56e-01 |
| Cellular-Senescence | 124 | 9.54e-01 | 0.954000 | 0.00952 | -0.00377 | -0.00874 | 9.42e-01 | 8.66e-01 |
Detailed Gene set reports
Downstream-signaling-events-of-B-Cell-Receptor-(BCR)
| metric | value |
|---|---|
| setSize | 79 |
| pMANOVA | 3.3e-06 |
| p.adjustMANOVA | 0.000152 |
| s.dist | 0.273 |
| s.diab | 0.0477 |
| s.PMX | -0.268 |
| p.diab | 0.463 |
| p.PMX | 3.7e-05 |
| Gene | diab | PMX |
|---|---|---|
| Nfkbia | 14941 | -14953 |
| Ppia | 14608 | -14924 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rps27a | 13894 | -14715 |
| Psma7 | 13781 | -14022 |
| Psmc3 | 13783 | -13466 |
| Psmb3 | 12063 | -13952 |
| Psmb6 | 11789 | -12835 |
| Hras | 12615 | -11955 |
| Nras | 11707 | -12390 |
| Ikbkg | 12618 | -11493 |
| Nfkbib | 12056 | -11601 |
| Psma6 | 9985 | -12478 |
| Psma3 | 9490 | -12548 |
| Map3k7 | 10607 | -11166 |
| Rel | 10291 | -11414 |
| Ppp3ca | 12376 | -9089 |
| Psmb5 | 10041 | -10541 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Bcl10 | -5706 | 6387 |
| Btrc | -1383 | 8479 |
| Calm1 | 152 | -11443 |
| Card11 | -7798 | 11685 |
| Chuk | -8103 | -8635 |
| Cul1 | 114 | -11623 |
| Fbxw11 | -10435 | 9702 |
| Fkbp1a | -4088 | 2763 |
| Hras | 12615 | -11955 |
| Ikbkb | -1527 | -10168 |
| Ikbkg | 12618 | -11493 |
| Kras | 8243 | -12396 |
| Malt1 | -6834 | 10147 |
| Map3k7 | 10607 | -11166 |
| Nfatc1 | -2618 | -8153 |
| Nfatc2 | 9333 | 9956 |
| Nfatc3 | -9186 | 3699 |
| Nfkb1 | 234 | 10216 |
| Nfkbia | 14941 | -14953 |
| Nfkbib | 12056 | -11601 |
| Nfkbie | -7903 | 8218 |
| Nras | 11707 | -12390 |
| Ppia | 14608 | -14924 |
| Ppp3ca | 12376 | -9089 |
| Ppp3cb | -6472 | 4604 |
| Ppp3r1 | 8691 | -9297 |
| Prkcb | -7742 | 7077 |
| Psma1 | -6738 | -7608 |
| Psma2 | 2844 | -13370 |
| Psma3 | 9490 | -12548 |
| Psma4 | 4617 | -12505 |
| Psma5 | 5504 | -11202 |
| Psma6 | 9985 | -12478 |
| Psma7 | 13781 | -14022 |
| Psma8 | -7575 | 7041 |
| Psmb1 | 6104 | -12225 |
| Psmb10 | 8202 | -4783 |
| Psmb11 | 5872 | -6129 |
| Psmb2 | 7847 | -11836 |
| Psmb3 | 12063 | -13952 |
| Psmb4 | -4466 | -8497 |
| Psmb5 | 10041 | -10541 |
| Psmb6 | 11789 | -12835 |
| Psmb7 | 175 | -13055 |
| Psmb8 | -5795 | 2962 |
| Psmb9 | -3858 | 5687 |
| Psmc1 | 11705 | -6393 |
| Psmc2 | -10211 | 7777 |
| Psmc3 | 13783 | -13466 |
| Psmc4 | -7487 | 10029 |
| Psmc5 | 5939 | -5097 |
| Psmc6 | -5320 | -12074 |
| Psmd1 | -4486 | -6816 |
| Psmd10 | -5266 | 7738 |
| Psmd11 | -4239 | -7981 |
| Psmd12 | -5190 | -6195 |
| Psmd13 | 10924 | -7634 |
| Psmd14 | -9498 | 2769 |
| Psmd2 | -11276 | 10253 |
| Psmd3 | 5369 | 146 |
| Psmd4 | 8666 | -10398 |
| Psmd5 | -1595 | -6026 |
| Psmd6 | -1663 | -8390 |
| Psmd7 | -9175 | -8611 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Psme2b | 158 | 1873 |
| Psme3 | -3827 | 9126 |
| Psme4 | -4545 | -7955 |
| Psmf1 | 3006 | 8610 |
| Rasgrp1 | -3739 | -13175 |
| Rasgrp3 | -12035 | 12755 |
| Rel | 10291 | -11414 |
| Rela | 7998 | -10978 |
| Rps27a | 13894 | -14715 |
| Skp1a | -9392 | 1413 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
Cell-Cycle-Checkpoints
| metric | value |
|---|---|
| setSize | 249 |
| pMANOVA | 1.04e-05 |
| p.adjustMANOVA | 0.000238 |
| s.dist | 0.227 |
| s.diab | 0.153 |
| s.PMX | -0.168 |
| p.diab | 3.01e-05 |
| p.PMX | 4.81e-06 |
| Gene | diab | PMX |
|---|---|---|
| Spc25 | 15273 | -15132 |
| Ppp2r5a | 14617 | -14818 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Brca1 | 14765 | -14101 |
| Rps27a | 13894 | -14715 |
| Rps27 | 13829 | -14647 |
| Dync1i2 | 13930 | -14334 |
| Dync1li2 | 13775 | -14349 |
| Cdkn1a | 15394 | -12557 |
| Psma7 | 13781 | -14022 |
| Ppp2cb | 14291 | -13381 |
| Zwint | 12999 | -14462 |
| Psmc3 | 13783 | -13466 |
| Rbbp8 | 13717 | -12966 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Bre | 14292 | -12007 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ahctf1 | -10865 | -10185 |
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Atm | 11462 | 2585 |
| Atr | 4265 | -9369 |
| Atrip | 8548 | -28 |
| Aurkb | 6296 | -7654 |
| B9d2 | -5649 | 8837 |
| Babam1 | -5669 | 6529 |
| Bard1 | 7141 | -328 |
| Birc5 | 12522 | -11275 |
| Blm | 13734 | -11646 |
| Brca1 | 14765 | -14101 |
| Brcc3 | 3410 | -9434 |
| Bre | 14292 | -12007 |
| Brip1 | 12955 | -13168 |
| Bub1 | 7301 | 7957 |
| Bub1b | 11232 | 4229 |
| Bub3 | -11165 | 11759 |
| Ccna2 | 12043 | -6678 |
| Ccnb1 | 14031 | -8068 |
| Ccnb2 | 10799 | -9616 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdc16 | 10625 | -286 |
| Cdc20 | 13126 | -4714 |
| Cdc23 | 180 | 8382 |
| Cdc25a | 3462 | -12613 |
| Cdc25c | 9859 | -6321 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdc45 | 8657 | -7688 |
| Cdc6 | -2324 | 4582 |
| Cdc7 | -9107 | 8769 |
| Cdca8 | 3238 | -2833 |
| Cdk1 | 12509 | -9455 |
| Cdk2 | 12902 | -12285 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Cenpa | 3435 | 5318 |
| Cenpc1 | -3272 | -8022 |
| Cenpe | 4365 | -6647 |
| Cenpf | 13427 | -379 |
| Cenph | 10433 | -9250 |
| Cenpi | 8123 | -7481 |
| Cenpk | 9317 | -8016 |
| Cenpl | -1784 | -10457 |
| Cenpm | 11559 | -9488 |
| Cenpn | 9068 | 4694 |
| Cenpo | 4588 | -8699 |
| Cenpp | 5610 | 4078 |
| Cenpq | -8830 | -3341 |
| Cenpt | 13110 | -10179 |
| Cenpu | 11737 | -7832 |
| Chek1 | 10916 | -6645 |
| Chek2 | -5693 | 11236 |
| Ckap5 | -1941 | 9831 |
| Clasp1 | 8043 | -6017 |
| Clasp2 | 14039 | -9470 |
| Clip1 | -3196 | -4018 |
| Clspn | -4322 | 6551 |
| Dbf4 | 11748 | -11992 |
| Dna2 | -7971 | 5856 |
| Dsn1 | 12989 | -13118 |
| Dync1h1 | 12037 | 3704 |
| Dync1i1 | 7564 | 7503 |
| Dync1i2 | 13930 | -14334 |
| Dync1li1 | 10870 | -10085 |
| Dync1li2 | 13775 | -14349 |
| Dynll1 | -10023 | -2241 |
| Dynll2 | -12351 | 10871 |
| Ercc6l | -7435 | 2783 |
| Exo1 | 11044 | -10136 |
| Fam175a | 6799 | 4765 |
| Gtse1 | 14189 | 5321 |
| H2afx | -3852 | 6424 |
| Herc2 | -7744 | 11170 |
| Hus1 | -10726 | 1804 |
| Incenp | 5723 | -3327 |
| Itgb3bp | 4897 | -8304 |
| Kat5 | 4420 | 6683 |
| Kif18a | -3219 | -3152 |
| Kif2a | 11818 | -4454 |
| Kif2c | 10981 | -8403 |
| Kntc1 | 11653 | -11626 |
| Mad1l1 | -2336 | 6065 |
| Mad2l1 | 12617 | -8263 |
| Mapre1 | 3104 | 2535 |
| Mcm10 | 3403 | 4685 |
| Mcm2 | -1041 | 10178 |
| Mcm3 | 3215 | 4597 |
| Mcm4 | -1878 | -3408 |
| Mcm5 | -4271 | 7491 |
| Mcm6 | 5041 | 5685 |
| Mcm7 | 6463 | 7251 |
| Mcm8 | 11218 | -4422 |
| Mdc1 | -4783 | 9438 |
| Mdm2 | 15095 | -7329 |
| Mdm4 | -4386 | -13416 |
| Mis12 | -8150 | 7697 |
| Mre11a | -5960 | 7726 |
| Nbn | -7224 | -4610 |
| Ndc80 | 11305 | -7543 |
| Nde1 | -6074 | 8864 |
| Ndel1 | -6462 | -13712 |
| Nsl1 | 2968 | 2930 |
| Nudc | 9181 | -10432 |
| Nuf2 | 8710 | -9737 |
| Nup107 | -4524 | -6225 |
| Nup133 | -6405 | 10731 |
| Nup160 | -7196 | -7326 |
| Nup37 | -4813 | 9951 |
| Nup43 | 8894 | -8868 |
| Nup85 | -9207 | 9918 |
| Nup98 | 10837 | 4406 |
| Orc1 | 9734 | -7991 |
| Orc2 | 2889 | -9894 |
| Orc3 | -4717 | 3382 |
| Orc4 | -5269 | -2439 |
| Orc5 | 10597 | -8072 |
| Orc6 | 374 | -7010 |
| Pafah1b1 | 4117 | -10743 |
| Pcbp4 | -10989 | 12360 |
| Phf20 | 12053 | -14031 |
| Pias4 | -9679 | 8206 |
| Pkmyt1 | 10003 | -8959 |
| Plk1 | 9395 | -5777 |
| Pmf1 | 13680 | -10495 |
| Ppp1cc | 13589 | -11988 |
| Ppp2ca | 2443 | 326 |
| Ppp2cb | 14291 | -13381 |
| Ppp2r1a | 11507 | 3755 |
| Ppp2r1b | -3062 | -7202 |
| Ppp2r5a | 14617 | -14818 |
| Ppp2r5b | -2576 | 4479 |
| Ppp2r5c | 12442 | -9365 |
| Ppp2r5d | 11554 | 1834 |
| Ppp2r5e | -4849 | 4842 |
| Psma1 | -6738 | -7608 |
| Psma2 | 2844 | -13370 |
| Psma3 | 9490 | -12548 |
| Psma4 | 4617 | -12505 |
| Psma5 | 5504 | -11202 |
| Psma6 | 9985 | -12478 |
| Psma7 | 13781 | -14022 |
| Psma8 | -7575 | 7041 |
| Psmb1 | 6104 | -12225 |
| Psmb10 | 8202 | -4783 |
| Psmb11 | 5872 | -6129 |
| Psmb2 | 7847 | -11836 |
| Psmb3 | 12063 | -13952 |
| Psmb4 | -4466 | -8497 |
| Psmb5 | 10041 | -10541 |
| Psmb6 | 11789 | -12835 |
| Psmb7 | 175 | -13055 |
| Psmb8 | -5795 | 2962 |
| Psmb9 | -3858 | 5687 |
| Psmc1 | 11705 | -6393 |
| Psmc2 | -10211 | 7777 |
| Psmc3 | 13783 | -13466 |
| Psmc4 | -7487 | 10029 |
| Psmc5 | 5939 | -5097 |
| Psmc6 | -5320 | -12074 |
| Psmd1 | -4486 | -6816 |
| Psmd10 | -5266 | 7738 |
| Psmd11 | -4239 | -7981 |
| Psmd12 | -5190 | -6195 |
| Psmd13 | 10924 | -7634 |
| Psmd14 | -9498 | 2769 |
| Psmd2 | -11276 | 10253 |
| Psmd3 | 5369 | 146 |
| Psmd4 | 8666 | -10398 |
| Psmd5 | -1595 | -6026 |
| Psmd6 | -1663 | -8390 |
| Psmd7 | -9175 | -8611 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Psme2b | 158 | 1873 |
| Psme3 | -3827 | 9126 |
| Psme4 | -4545 | -7955 |
| Psmf1 | 3006 | 8610 |
| Rad1 | -6955 | 4321 |
| Rad17 | 226 | -6799 |
| Rad50 | 9654 | -3235 |
| Rad9a | 8550 | 4566 |
| Rad9b | 6251 | -7308 |
| Ranbp2 | -1884 | -9227 |
| Rangap1 | -4113 | 2101 |
| Rbbp8 | 13717 | -12966 |
| Rcc2 | 2405 | 7611 |
| Rfc2 | -6748 | 11476 |
| Rfc3 | 13044 | -6703 |
| Rfc4 | 3874 | 2158 |
| Rfc5 | 12334 | 8699 |
| Rfwd2 | -2988 | -5509 |
| Rhno1 | 7419 | -5059 |
| Rmi1 | -9220 | 10169 |
| Rmi2 | 9282 | 3955 |
| Rnf168 | -4091 | -149 |
| Rnf8 | -2987 | -6982 |
| Rpa1 | -5523 | 11078 |
| Rpa2 | 6898 | -2423 |
| Rpa3 | -2462 | 3353 |
| Rps27 | 13829 | -14647 |
| Rps27a | 13894 | -14715 |
| Sec13 | 9849 | -12486 |
| Seh1l | 9415 | -7505 |
| Sfn | 9301 | 71 |
| Sgol1 | -1679 | 7844 |
| Sgol2a | 8718 | -3548 |
| Ska1 | 6709 | -10296 |
| Ska2 | -9526 | 7541 |
| Spc24 | 13403 | -11390 |
| Spc25 | 15273 | -15132 |
| Spdl1 | 10773 | -10080 |
| Sumo1 | -5337 | -10745 |
| Taok1 | -4234 | -10641 |
| Top3a | -8478 | -5110 |
| Topbp1 | 4504 | -5842 |
| Trp53 | -7681 | 5460 |
| Trp53bp1 | -9861 | 10372 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
| Ube2v2 | -8928 | 4163 |
| Uimc1 | -4365 | 352 |
| Wee1 | 249 | -14752 |
| Wrn | -3128 | 5665 |
| Xpo1 | -10778 | 9680 |
| Ywhab | -3531 | -52 |
| Ywhae | 2275 | -8018 |
| Ywhag | -10205 | 10203 |
| Ywhah | 3055 | -11126 |
| Ywhaq | 12431 | -12558 |
| Zfp385a | 15036 | -8764 |
| Zw10 | -5911 | 7531 |
| Zwilch | 13125 | -12780 |
| Zwint | 12999 | -14462 |
APC:Cdc20-mediated-degradation-of-cell-cycle-proteins-prior-to-satisfation-of-the-cell-cycle-checkpoint
| metric | value |
|---|---|
| setSize | 71 |
| pMANOVA | 3.41e-05 |
| p.adjustMANOVA | 0.000523 |
| s.dist | 0.337 |
| s.diab | 0.15 |
| s.PMX | -0.301 |
| p.diab | 0.0285 |
| p.PMX | 1.11e-05 |
| Gene | diab | PMX |
|---|---|---|
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rps27a | 13894 | -14715 |
| Psma7 | 13781 | -14022 |
| Psmc3 | 13783 | -13466 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Psmb3 | 12063 | -13952 |
| Nek2 | 14119 | -11365 |
| Ube2d1 | 11721 | -13291 |
| Psmb6 | 11789 | -12835 |
| Psma6 | 9985 | -12478 |
| Psma3 | 9490 | -12548 |
| Cdk1 | 12509 | -9455 |
| Psmb5 | 10041 | -10541 |
| Mad2l1 | 12617 | -8263 |
| Psmb2 | 7847 | -11836 |
| Psmd4 | 8666 | -10398 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Bub1b | 11232 | 4229 |
| Bub3 | -11165 | 11759 |
| Ccna2 | 12043 | -6678 |
| Cdc16 | 10625 | -286 |
| Cdc20 | 13126 | -4714 |
| Cdc23 | 180 | 8382 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdk1 | 12509 | -9455 |
| Mad2l1 | 12617 | -8263 |
| Nek2 | 14119 | -11365 |
| Psma1 | -6738 | -7608 |
| Psma2 | 2844 | -13370 |
| Psma3 | 9490 | -12548 |
| Psma4 | 4617 | -12505 |
| Psma5 | 5504 | -11202 |
| Psma6 | 9985 | -12478 |
| Psma7 | 13781 | -14022 |
| Psma8 | -7575 | 7041 |
| Psmb1 | 6104 | -12225 |
| Psmb10 | 8202 | -4783 |
| Psmb11 | 5872 | -6129 |
| Psmb2 | 7847 | -11836 |
| Psmb3 | 12063 | -13952 |
| Psmb4 | -4466 | -8497 |
| Psmb5 | 10041 | -10541 |
| Psmb6 | 11789 | -12835 |
| Psmb7 | 175 | -13055 |
| Psmb8 | -5795 | 2962 |
| Psmb9 | -3858 | 5687 |
| Psmc1 | 11705 | -6393 |
| Psmc2 | -10211 | 7777 |
| Psmc3 | 13783 | -13466 |
| Psmc4 | -7487 | 10029 |
| Psmc5 | 5939 | -5097 |
| Psmc6 | -5320 | -12074 |
| Psmd1 | -4486 | -6816 |
| Psmd10 | -5266 | 7738 |
| Psmd11 | -4239 | -7981 |
| Psmd12 | -5190 | -6195 |
| Psmd13 | 10924 | -7634 |
| Psmd14 | -9498 | 2769 |
| Psmd2 | -11276 | 10253 |
| Psmd3 | 5369 | 146 |
| Psmd4 | 8666 | -10398 |
| Psmd5 | -1595 | -6026 |
| Psmd6 | -1663 | -8390 |
| Psmd7 | -9175 | -8611 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Psme2b | 158 | 1873 |
| Psme3 | -3827 | 9126 |
| Psme4 | -4545 | -7955 |
| Psmf1 | 3006 | 8610 |
| Rps27a | 13894 | -14715 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
APC/C-mediated-degradation-of-cell-cycle-proteins
| metric | value |
|---|---|
| setSize | 85 |
| pMANOVA | 6.82e-05 |
| p.adjustMANOVA | 0.000628 |
| s.dist | 0.31 |
| s.diab | 0.152 |
| s.PMX | -0.271 |
| p.diab | 0.0156 |
| p.PMX | 1.57e-05 |
| Gene | diab | PMX |
|---|---|---|
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rb1 | 15102 | -13818 |
| Rps27a | 13894 | -14715 |
| Psma7 | 13781 | -14022 |
| Psmc3 | 13783 | -13466 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Psmb3 | 12063 | -13952 |
| Nek2 | 14119 | -11365 |
| Cdk2 | 12902 | -12285 |
| Ube2d1 | 11721 | -13291 |
| Pttg1 | 13199 | -11759 |
| Psmb6 | 11789 | -12835 |
| Psma6 | 9985 | -12478 |
| Psma3 | 9490 | -12548 |
| Cdk1 | 12509 | -9455 |
| Ccnb1 | 14031 | -8068 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Aurka | 12135 | -7881 |
| Aurkb | 6296 | -7654 |
| Btrc | -1383 | 8479 |
| Bub1b | 11232 | 4229 |
| Bub3 | -11165 | 11759 |
| Ccna2 | 12043 | -6678 |
| Ccnb1 | 14031 | -8068 |
| Cdc14a | -8389 | 10394 |
| Cdc16 | 10625 | -286 |
| Cdc20 | 13126 | -4714 |
| Cdc23 | 180 | 8382 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdk1 | 12509 | -9455 |
| Cdk2 | 12902 | -12285 |
| Cul1 | 114 | -11623 |
| Fbxo5 | -1870 | 5491 |
| Fzr1 | -2715 | 9851 |
| Mad2l1 | 12617 | -8263 |
| Nek2 | 14119 | -11365 |
| Plk1 | 9395 | -5777 |
| Psma1 | -6738 | -7608 |
| Psma2 | 2844 | -13370 |
| Psma3 | 9490 | -12548 |
| Psma4 | 4617 | -12505 |
| Psma5 | 5504 | -11202 |
| Psma6 | 9985 | -12478 |
| Psma7 | 13781 | -14022 |
| Psma8 | -7575 | 7041 |
| Psmb1 | 6104 | -12225 |
| Psmb10 | 8202 | -4783 |
| Psmb11 | 5872 | -6129 |
| Psmb2 | 7847 | -11836 |
| Psmb3 | 12063 | -13952 |
| Psmb4 | -4466 | -8497 |
| Psmb5 | 10041 | -10541 |
| Psmb6 | 11789 | -12835 |
| Psmb7 | 175 | -13055 |
| Psmb8 | -5795 | 2962 |
| Psmb9 | -3858 | 5687 |
| Psmc1 | 11705 | -6393 |
| Psmc2 | -10211 | 7777 |
| Psmc3 | 13783 | -13466 |
| Psmc4 | -7487 | 10029 |
| Psmc5 | 5939 | -5097 |
| Psmc6 | -5320 | -12074 |
| Psmd1 | -4486 | -6816 |
| Psmd10 | -5266 | 7738 |
| Psmd11 | -4239 | -7981 |
| Psmd12 | -5190 | -6195 |
| Psmd13 | 10924 | -7634 |
| Psmd14 | -9498 | 2769 |
| Psmd2 | -11276 | 10253 |
| Psmd3 | 5369 | 146 |
| Psmd4 | 8666 | -10398 |
| Psmd5 | -1595 | -6026 |
| Psmd6 | -1663 | -8390 |
| Psmd7 | -9175 | -8611 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Psme2b | 158 | 1873 |
| Psme3 | -3827 | 9126 |
| Psme4 | -4545 | -7955 |
| Psmf1 | 3006 | 8610 |
| Pttg1 | 13199 | -11759 |
| Rb1 | 15102 | -13818 |
| Rps27a | 13894 | -14715 |
| Skp1a | -9392 | 1413 |
| Skp2 | -9937 | 5846 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
Regulation-of-mitotic-cell-cycle
| metric | value |
|---|---|
| setSize | 85 |
| pMANOVA | 6.82e-05 |
| p.adjustMANOVA | 0.000628 |
| s.dist | 0.31 |
| s.diab | 0.152 |
| s.PMX | -0.271 |
| p.diab | 0.0156 |
| p.PMX | 1.57e-05 |
| Gene | diab | PMX |
|---|---|---|
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rb1 | 15102 | -13818 |
| Rps27a | 13894 | -14715 |
| Psma7 | 13781 | -14022 |
| Psmc3 | 13783 | -13466 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Psmb3 | 12063 | -13952 |
| Nek2 | 14119 | -11365 |
| Cdk2 | 12902 | -12285 |
| Ube2d1 | 11721 | -13291 |
| Pttg1 | 13199 | -11759 |
| Psmb6 | 11789 | -12835 |
| Psma6 | 9985 | -12478 |
| Psma3 | 9490 | -12548 |
| Cdk1 | 12509 | -9455 |
| Ccnb1 | 14031 | -8068 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Aurka | 12135 | -7881 |
| Aurkb | 6296 | -7654 |
| Btrc | -1383 | 8479 |
| Bub1b | 11232 | 4229 |
| Bub3 | -11165 | 11759 |
| Ccna2 | 12043 | -6678 |
| Ccnb1 | 14031 | -8068 |
| Cdc14a | -8389 | 10394 |
| Cdc16 | 10625 | -286 |
| Cdc20 | 13126 | -4714 |
| Cdc23 | 180 | 8382 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdk1 | 12509 | -9455 |
| Cdk2 | 12902 | -12285 |
| Cul1 | 114 | -11623 |
| Fbxo5 | -1870 | 5491 |
| Fzr1 | -2715 | 9851 |
| Mad2l1 | 12617 | -8263 |
| Nek2 | 14119 | -11365 |
| Plk1 | 9395 | -5777 |
| Psma1 | -6738 | -7608 |
| Psma2 | 2844 | -13370 |
| Psma3 | 9490 | -12548 |
| Psma4 | 4617 | -12505 |
| Psma5 | 5504 | -11202 |
| Psma6 | 9985 | -12478 |
| Psma7 | 13781 | -14022 |
| Psma8 | -7575 | 7041 |
| Psmb1 | 6104 | -12225 |
| Psmb10 | 8202 | -4783 |
| Psmb11 | 5872 | -6129 |
| Psmb2 | 7847 | -11836 |
| Psmb3 | 12063 | -13952 |
| Psmb4 | -4466 | -8497 |
| Psmb5 | 10041 | -10541 |
| Psmb6 | 11789 | -12835 |
| Psmb7 | 175 | -13055 |
| Psmb8 | -5795 | 2962 |
| Psmb9 | -3858 | 5687 |
| Psmc1 | 11705 | -6393 |
| Psmc2 | -10211 | 7777 |
| Psmc3 | 13783 | -13466 |
| Psmc4 | -7487 | 10029 |
| Psmc5 | 5939 | -5097 |
| Psmc6 | -5320 | -12074 |
| Psmd1 | -4486 | -6816 |
| Psmd10 | -5266 | 7738 |
| Psmd11 | -4239 | -7981 |
| Psmd12 | -5190 | -6195 |
| Psmd13 | 10924 | -7634 |
| Psmd14 | -9498 | 2769 |
| Psmd2 | -11276 | 10253 |
| Psmd3 | 5369 | 146 |
| Psmd4 | 8666 | -10398 |
| Psmd5 | -1595 | -6026 |
| Psmd6 | -1663 | -8390 |
| Psmd7 | -9175 | -8611 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Psme2b | 158 | 1873 |
| Psme3 | -3827 | 9126 |
| Psme4 | -4545 | -7955 |
| Psmf1 | 3006 | 8610 |
| Pttg1 | 13199 | -11759 |
| Rb1 | 15102 | -13818 |
| Rps27a | 13894 | -14715 |
| Skp1a | -9392 | 1413 |
| Skp2 | -9937 | 5846 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
Cell-Cycle,-Mitotic
| metric | value |
|---|---|
| setSize | 479 |
| pMANOVA | 9.44e-05 |
| p.adjustMANOVA | 0.000724 |
| s.dist | 0.142 |
| s.diab | 0.114 |
| s.PMX | -0.0849 |
| p.diab | 1.78e-05 |
| p.PMX | 0.00141 |
| Gene | diab | PMX |
|---|---|---|
| Ccnd3 | 15351 | -15060 |
| Spc25 | 15273 | -15132 |
| Chmp4c | 14654 | -14956 |
| Ppp2r5a | 14617 | -14818 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rb1 | 15102 | -13818 |
| Optn | 15124 | -13664 |
| Cdkn2b | 14383 | -14293 |
| Rps27a | 13894 | -14715 |
| Rps27 | 13829 | -14647 |
| Nek6 | 13921 | -14431 |
| Dync1i2 | 13930 | -14334 |
| Dync1li2 | 13775 | -14349 |
| Golga2 | 14538 | -13457 |
| E2f1 | 14773 | -13127 |
| Cdkn1a | 15394 | -12557 |
| Psma7 | 13781 | -14022 |
| Ube2i | 13984 | -13775 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| 1700123L14Rik | -2109.5 | 2317.5 |
| Aaas | 13184.0 | 10673.0 |
| Abl1 | 6603.0 | -4424.0 |
| Actr1a | 10383.0 | -8216.0 |
| Ahctf1 | -10865.0 | -10185.0 |
| Ajuba | -11055.0 | 10965.0 |
| Akap9 | 5910.0 | -8203.0 |
| Akt1 | 11899.0 | -4407.0 |
| Akt2 | -10282.0 | 10289.0 |
| Akt3 | -23.0 | -6307.0 |
| Alms1 | -11955.0 | 12031.0 |
| Anapc1 | -11278.0 | 10450.0 |
| Anapc10 | -40.0 | -7692.0 |
| Anapc11 | -4767.0 | -2276.0 |
| Anapc15 | -2513.0 | -9553.0 |
| Anapc16 | 13128.0 | -13447.0 |
| Anapc2 | -3217.0 | 9388.0 |
| Anapc4 | 14276.0 | -12248.0 |
| Anapc5 | 14536.0 | -12088.0 |
| Anapc7 | 10824.0 | -6183.0 |
| Ankle2 | 2982.0 | 3698.0 |
| Arpp19 | -10703.0 | 11233.0 |
| Aurka | 12135.0 | -7881.0 |
| Aurkb | 6296.0 | -7654.0 |
| B9d2 | -5649.0 | 8837.0 |
| Banf1 | 9290.0 | -8382.0 |
| Birc5 | 12522.0 | -11275.0 |
| Blzf1 | 7887.0 | -3336.0 |
| Bmyc | 6106.0 | 3479.0 |
| Bora | 10161.0 | -12351.0 |
| Btrc | -1383.0 | 8479.0 |
| Bub1 | 7301.0 | 7957.0 |
| Bub1b | 11232.0 | 4229.0 |
| Bub3 | -11165.0 | 11759.0 |
| Cables1 | 2270.0 | 12575.0 |
| Cc2d1b | 8641.0 | 7466.0 |
| Ccna2 | 12043.0 | -6678.0 |
| Ccnb1 | 14031.0 | -8068.0 |
| Ccnb2 | 10799.0 | -9616.0 |
| Ccnd1 | 10280.0 | 12715.0 |
| Ccnd2 | -10391.0 | 11271.0 |
| Ccnd3 | 15351.0 | -15060.0 |
| Ccne1 | 8507.0 | -10924.0 |
| Ccne2 | 4837.0 | -11061.0 |
| Ccnh | -9565.0 | 9010.0 |
| Ccp110 | -3885.0 | -8946.0 |
| Cdc14a | -8389.0 | 10394.0 |
| Cdc16 | 10625.0 | -286.0 |
| Cdc20 | 13126.0 | -4714.0 |
| Cdc23 | 180.0 | 8382.0 |
| Cdc25a | 3462.0 | -12613.0 |
| Cdc25b | 8473.0 | 6982.0 |
| Cdc25c | 9859.0 | -6321.0 |
| Cdc26 | 8205.0 | -5823.0 |
| Cdc27 | -6730.0 | -6274.0 |
| Cdc45 | 8657.0 | -7688.0 |
| Cdc6 | -2324.0 | 4582.0 |
| Cdc7 | -9107.0 | 8769.0 |
| Cdca5 | 6525.0 | 30.0 |
| Cdca8 | 3238.0 | -2833.0 |
| Cdk1 | 12509.0 | -9455.0 |
| Cdk11b | 10589.0 | -10741.0 |
| Cdk2 | 12902.0 | -12285.0 |
| Cdk4 | 7497.0 | 6438.0 |
| Cdk5rap2 | -7137.0 | 3897.0 |
| Cdk6 | -8022.0 | -8784.0 |
| Cdk7 | -6948.0 | 4688.0 |
| Cdkn1a | 15394.0 | -12557.0 |
| Cdkn1b | 4380.0 | 258.0 |
| Cdkn1c | 11412.0 | 12041.0 |
| Cdkn2b | 14383.0 | -14293.0 |
| Cdkn2c | -1158.0 | 9132.0 |
| Cdkn2d | 5293.0 | 2129.0 |
| Cdt1 | 8222.0 | -9768.0 |
| Cenpa | 3435.0 | 5318.0 |
| Cenpc1 | -3272.0 | -8022.0 |
| Cenpe | 4365.0 | -6647.0 |
| Cenpf | 13427.0 | -379.0 |
| Cenph | 10433.0 | -9250.0 |
| Cenpi | 8123.0 | -7481.0 |
| Cenpj | -11728.0 | 6522.0 |
| Cenpk | 9317.0 | -8016.0 |
| Cenpl | -1784.0 | -10457.0 |
| Cenpm | 11559.0 | -9488.0 |
| Cenpn | 9068.0 | 4694.0 |
| Cenpo | 4588.0 | -8699.0 |
| Cenpp | 5610.0 | 4078.0 |
| Cenpq | -8830.0 | -3341.0 |
| Cenpt | 13110.0 | -10179.0 |
| Cenpu | 11737.0 | -7832.0 |
| Cep131 | 11325.0 | -5598.0 |
| Cep135 | -3810.0 | 8621.0 |
| Cep152 | -1773.0 | 196.0 |
| Cep164 | 8128.0 | 5691.0 |
| Cep192 | 52.0 | 8736.0 |
| Cep250 | -3793.0 | 9525.0 |
| Cep290 | -10441.0 | 11686.0 |
| Cep41 | -10073.0 | 11800.0 |
| Cep57 | 8021.0 | -13087.0 |
| Cep63 | -3404.0 | -10352.0 |
| Cep70 | 12768.0 | 392.0 |
| Cep72 | 8804.0 | 5042.0 |
| Cep76 | -5040.0 | 5787.0 |
| Cep78 | -9622.0 | 4307.0 |
| Cetn2 | -9237.0 | 3491.0 |
| Chmp2a | 6531.0 | -8482.0 |
| Chmp2b | 11049.0 | -9912.0 |
| Chmp3 | 8777.0 | -13102.0 |
| Chmp4b | 13369.0 | -13601.0 |
| Chmp4c | 14654.0 | -14956.0 |
| Chmp6 | 9126.0 | 9611.0 |
| Chmp7 | -7612.0 | 12648.0 |
| Ckap5 | -1941.0 | 9831.0 |
| Cks1b | 12264.0 | -6528.0 |
| Clasp1 | 8043.0 | -6017.0 |
| Clasp2 | 14039.0 | -9470.0 |
| Clip1 | -3196.0 | -4018.0 |
| Cnep1r1 | 4530.0 | -11794.0 |
| Cntrl | 10308.0 | -9086.0 |
| Csnk1d | 4297.0 | -10796.0 |
| Csnk1e | 10966.0 | -7406.0 |
| Csnk2a1 | 111.0 | -6883.0 |
| Csnk2a2 | 4776.0 | -8371.0 |
| Csnk2b | 4564.0 | -136.0 |
| Ctdnep1 | -10262.0 | 11004.0 |
| Cul1 | 114.0 | -11623.0 |
| Dbf4 | 11748.0 | -11992.0 |
| Dctn1 | 4613.0 | 8656.0 |
| Dctn2 | 13574.0 | -8129.0 |
| Dctn3 | 13985.0 | -13682.0 |
| Dhfr | -11741.0 | 10911.0 |
| Dna2 | -7971.0 | 5856.0 |
| Dsn1 | 12989.0 | -13118.0 |
| Dync1h1 | 12037.0 | 3704.0 |
| Dync1i1 | 7564.0 | 7503.0 |
| Dync1i2 | 13930.0 | -14334.0 |
| Dync1li1 | 10870.0 | -10085.0 |
| Dync1li2 | 13775.0 | -14349.0 |
| Dynll1 | -10023.0 | -2241.0 |
| Dynll2 | -12351.0 | 10871.0 |
| Dyrk1a | 6379.0 | -5909.0 |
| E2f1 | 14773.0 | -13127.0 |
| E2f2 | -10922.0 | 8773.0 |
| E2f3 | 9873.0 | 3869.0 |
| E2f4 | -8258.0 | 5909.0 |
| E2f5 | -12272.0 | 11795.0 |
| E2f6 | -11558.0 | 12122.0 |
| Emd | 9167.0 | -10589.0 |
| Eml4 | 398.0 | 4690.0 |
| Ensa | 4482.0 | -12626.0 |
| Ep300 | -10091.0 | 9600.0 |
| Ercc6l | -7435.0 | 2783.0 |
| Esco1 | -6644.0 | 1090.0 |
| Esco2 | 11918.0 | -9481.0 |
| Espl1 | 7494.0 | -361.0 |
| Fbxl18 | -8136.0 | 9051.0 |
| Fbxl7 | -276.0 | 7460.0 |
| Fbxo5 | -1870.0 | 5491.0 |
| Fbxw11 | -10435.0 | 9702.0 |
| Fen1 | 7543.0 | 234.0 |
| Fkbpl | -5916.0 | 4598.0 |
| Foxm1 | 12715.0 | -5772.0 |
| Fzr1 | -2715.0 | 9851.0 |
| Gins1 | -4499.0 | 1259.0 |
| Gins2 | 14037.0 | -12388.0 |
| Gins3 | -2737.0 | -3111.0 |
| Gins4 | 6658.0 | -4395.0 |
| Gmnn | 12869.0 | -13700.0 |
| Golga2 | 14538.0 | -13457.0 |
| Gorasp1 | -11150.0 | 12579.0 |
| Gorasp2 | 2975.0 | 3355.0 |
| Gsk3b | -6315.0 | 7700.0 |
| Gtse1 | 14189.0 | 5321.0 |
| H2afx | -3852.0 | 6424.0 |
| Haus1 | 9580.0 | -4996.0 |
| Haus2 | -1376.0 | -9517.0 |
| Haus3 | 12682.0 | -12876.0 |
| Haus4 | 13772.0 | -8411.0 |
| Haus5 | 3099.0 | 5247.0 |
| Haus6 | -4075.0 | -11789.0 |
| Haus7 | 14036.0 | -9664.0 |
| Haus8 | 9204.0 | 3914.0 |
| Hdac1 | -10878.0 | 10117.0 |
| Hdac8 | 5664.0 | -6069.0 |
| Hmmr | 13358.0 | -11832.0 |
| Hsp90aa1 | -12505.0 | 4614.0 |
| Hsp90ab1 | -12580.0 | 11764.0 |
| Incenp | 5723.0 | -3327.0 |
| Ist1 | 8650.0 | 5536.0 |
| Itgb3bp | 4897.0 | -8304.0 |
| Jak2 | -8549.0 | -13401.0 |
| Kif18a | -3219.0 | -3152.0 |
| Kif20a | 13428.0 | -4447.0 |
| Kif23 | 14225.0 | -12979.0 |
| Kif2a | 11818.0 | -4454.0 |
| Kif2c | 10981.0 | -8403.0 |
| Kmt5a | 5653.0 | 6397.0 |
| Kntc1 | 11653.0 | -11626.0 |
| Kpnb1 | 10908.0 | 1199.0 |
| Lbr | -12455.0 | 12869.0 |
| Lcmt1 | 13397.0 | -7684.0 |
| Lemd2 | 4754.0 | 6810.0 |
| Lemd3 | 2945.0 | -5014.0 |
| Lig1 | 13161.0 | -4756.0 |
| Lin37 | -7391.0 | 6267.0 |
| Lin52 | 9562.0 | -7056.0 |
| Lin54 | -5778.0 | 5287.0 |
| Lin9 | 7699.0 | -11842.0 |
| Lmna | 5606.0 | 3857.0 |
| Lmnb1 | -9916.0 | 8126.0 |
| Lpin1 | 13638.0 | -14073.0 |
| Lpin2 | 12674.0 | -14612.0 |
| Lpin3 | 14358.0 | -8350.0 |
| Lyn | -7639.0 | 6.0 |
| Mad1l1 | -2336.0 | 6065.0 |
| Mad2l1 | 12617.0 | -8263.0 |
| Mapk1 | 6867.0 | -10406.0 |
| Mapk3 | 10588.0 | -6813.0 |
| Mapre1 | 3104.0 | 2535.0 |
| Mastl | 9321.0 | -5732.0 |
| Mau2 | 13230.0 | -13597.0 |
| Max | 13684.0 | -12344.0 |
| Mcm10 | 3403.0 | 4685.0 |
| Mcm2 | -1041.0 | 10178.0 |
| Mcm3 | 3215.0 | 4597.0 |
| Mcm4 | -1878.0 | -3408.0 |
| Mcm5 | -4271.0 | 7491.0 |
| Mcm6 | 5041.0 | 5685.0 |
| Mcm7 | 6463.0 | 7251.0 |
| Mcm8 | 11218.0 | -4422.0 |
| Mcph1 | 8663.0 | -388.0 |
| Mis12 | -8150.0 | 7697.0 |
| Mnat1 | 5792.0 | 4333.0 |
| Mybl2 | 11695.0 | -13356.0 |
| Mzt1 | 10494.0 | -12063.0 |
| Mzt2 | 10538.0 | -7815.0 |
| Ncapd2 | 10711.0 | -105.0 |
| Ncapd3 | 11681.0 | -13198.0 |
| Ncapg | 8006.0 | 5170.0 |
| Ncapg2 | 13407.0 | -8517.0 |
| Ncaph | 9662.0 | -7763.0 |
| Ncaph2 | 4224.0 | 91.0 |
| Ndc1 | 13238.0 | -12109.0 |
| Ndc80 | 11305.0 | -7543.0 |
| Nde1 | -6074.0 | 8864.0 |
| Ndel1 | -6462.0 | -13712.0 |
| Nedd1 | -5802.0 | -9203.0 |
| Nek2 | 14119.0 | -11365.0 |
| Nek6 | 13921.0 | -14431.0 |
| Nek7 | -8839.0 | 7258.0 |
| Nek9 | -8705.0 | 11327.0 |
| Ninl | 12966.0 | -10855.0 |
| Nipbl | -7169.0 | -3159.0 |
| Nme7 | -10054.0 | 6679.0 |
| Nsl1 | 2968.0 | 2930.0 |
| Nudc | 9181.0 | -10432.0 |
| Nuf2 | 8710.0 | -9737.0 |
| Numa1 | -6029.0 | 10210.0 |
| Nup107 | -4524.0 | -6225.0 |
| Nup133 | -6405.0 | 10731.0 |
| Nup153 | -10729.0 | 9979.0 |
| Nup155 | 11046.0 | -12223.0 |
| Nup160 | -7196.0 | -7326.0 |
| Nup188 | -6119.0 | 7249.0 |
| Nup205 | 5816.0 | 3749.0 |
| Nup210 | 14542.0 | -63.0 |
| Nup214 | 13088.0 | -10974.0 |
| Nup35 | -8231.0 | 10983.0 |
| Nup37 | -4813.0 | 9951.0 |
| Nup43 | 8894.0 | -8868.0 |
| Nup54 | -6950.0 | 2963.0 |
| Nup62 | -8836.0 | 8004.0 |
| Nup85 | -9207.0 | 9918.0 |
| Nup88 | 14341.0 | -12858.0 |
| Nup93 | 12551.0 | 5537.0 |
| Nup98 | 10837.0 | 4406.0 |
| Nupl1 | 11303.0 | -7772.0 |
| Odf2 | 12329.0 | -8688.0 |
| Ofd1 | 12344.0 | -10416.0 |
| Optn | 15124.0 | -13664.0 |
| Orc1 | 9734.0 | -7991.0 |
| Orc2 | 2889.0 | -9894.0 |
| Orc3 | -4717.0 | 3382.0 |
| Orc4 | -5269.0 | -2439.0 |
| Orc5 | 10597.0 | -8072.0 |
| Orc6 | 374.0 | -7010.0 |
| Pafah1b1 | 4117.0 | -10743.0 |
| Pcm1 | 11605.0 | -13363.0 |
| Pcna | 13367.0 | -14114.0 |
| Pcnt | 11489.0 | -8081.0 |
| Pds5a | -2274.0 | -8133.0 |
| Pds5b | -8117.0 | 11104.0 |
| Phf8 | -1381.0 | -4659.0 |
| Phlda1 | -8040.0 | 9959.0 |
| Pkmyt1 | 10003.0 | -8959.0 |
| Plk1 | 9395.0 | -5777.0 |
| Plk4 | 2268.0 | -7402.0 |
| Pmf1 | 13680.0 | -10495.0 |
| Pola1 | -8880.0 | 5777.0 |
| Pola2 | 8004.0 | -5681.0 |
| Pold1 | 5255.0 | 4543.0 |
| Pold2 | 12631.0 | -8485.0 |
| Pold3 | -4233.0 | 6741.0 |
| Pold4 | 7034.0 | -12051.0 |
| Pole | 11606.0 | -7660.0 |
| Pole2 | -7143.0 | -143.0 |
| Pole3 | 10431.0 | -13031.0 |
| Pole4 | -11603.0 | 7992.0 |
| Pom121 | 9659.0 | -12785.0 |
| Ppme1 | 3702.0 | 3.0 |
| Ppp1cb | 4565.0 | -10643.0 |
| Ppp1cc | 13589.0 | -11988.0 |
| Ppp1r12a | 3470.0 | -9878.0 |
| Ppp1r12b | -7715.0 | 11767.0 |
| Ppp2ca | 2443.0 | 326.0 |
| Ppp2cb | 14291.0 | -13381.0 |
| Ppp2r1a | 11507.0 | 3755.0 |
| Ppp2r1b | -3062.0 | -7202.0 |
| Ppp2r2a | -1142.0 | -9444.0 |
| Ppp2r2d | 12749.0 | -14570.0 |
| Ppp2r3d | -3033.0 | 6807.0 |
| Ppp2r5a | 14617.0 | -14818.0 |
| Ppp2r5b | -2576.0 | 4479.0 |
| Ppp2r5c | 12442.0 | -9365.0 |
| Ppp2r5d | 11554.0 | 1834.0 |
| Ppp2r5e | -4849.0 | 4842.0 |
| Prim1 | -8624.0 | 10425.0 |
| Prim2 | -9097.0 | 5742.0 |
| Prkar2b | -11024.0 | 2146.0 |
| Prkca | -11577.0 | 11021.0 |
| Prkcb | -7742.0 | 7077.0 |
| Psma1 | -6738.0 | -7608.0 |
| Psma2 | 2844.0 | -13370.0 |
| Psma3 | 9490.0 | -12548.0 |
| Psma4 | 4617.0 | -12505.0 |
| Psma5 | 5504.0 | -11202.0 |
| Psma6 | 9985.0 | -12478.0 |
| Psma7 | 13781.0 | -14022.0 |
| Psma8 | -7575.0 | 7041.0 |
| Psmb1 | 6104.0 | -12225.0 |
| Psmb10 | 8202.0 | -4783.0 |
| Psmb11 | 5872.0 | -6129.0 |
| Psmb2 | 7847.0 | -11836.0 |
| Psmb3 | 12063.0 | -13952.0 |
| Psmb4 | -4466.0 | -8497.0 |
| Psmb5 | 10041.0 | -10541.0 |
| Psmb6 | 11789.0 | -12835.0 |
| Psmb7 | 175.0 | -13055.0 |
| Psmb8 | -5795.0 | 2962.0 |
| Psmb9 | -3858.0 | 5687.0 |
| Psmc1 | 11705.0 | -6393.0 |
| Psmc2 | -10211.0 | 7777.0 |
| Psmc3 | 13783.0 | -13466.0 |
| Psmc4 | -7487.0 | 10029.0 |
| Psmc5 | 5939.0 | -5097.0 |
| Psmc6 | -5320.0 | -12074.0 |
| Psmd1 | -4486.0 | -6816.0 |
| Psmd10 | -5266.0 | 7738.0 |
| Psmd11 | -4239.0 | -7981.0 |
| Psmd12 | -5190.0 | -6195.0 |
| Psmd13 | 10924.0 | -7634.0 |
| Psmd14 | -9498.0 | 2769.0 |
| Psmd2 | -11276.0 | 10253.0 |
| Psmd3 | 5369.0 | 146.0 |
| Psmd4 | 8666.0 | -10398.0 |
| Psmd5 | -1595.0 | -6026.0 |
| Psmd6 | -1663.0 | -8390.0 |
| Psmd7 | -9175.0 | -8611.0 |
| Psmd8 | 14709.0 | -14720.0 |
| Psmd9 | 14751.0 | -14675.0 |
| Psme1 | 14335.0 | -14654.0 |
| Psme2b | 158.0 | 1873.0 |
| Psme3 | -3827.0 | 9126.0 |
| Psme4 | -4545.0 | -7955.0 |
| Psmf1 | 3006.0 | 8610.0 |
| Ptk6 | -8916.0 | 7487.0 |
| Pttg1 | 13199.0 | -11759.0 |
| Rab1a | -8474.0 | 2511.0 |
| Rab1b | -6847.0 | 3621.0 |
| Rab2a | -8200.0 | -6726.0 |
| Rab8a | -7413.0 | -3395.0 |
| Rad21 | -6091.0 | -9748.0 |
| Rae1 | -2818.0 | 7959.0 |
| Ran | -340.0 | -458.0 |
| Ranbp2 | -1884.0 | -9227.0 |
| Rangap1 | -4113.0 | 2101.0 |
| Rb1 | 15102.0 | -13818.0 |
| Rbbp4 | -12462.0 | 12126.0 |
| Rbl1 | -9375.0 | 11563.0 |
| Rbl2 | 11787.0 | -7420.0 |
| Rbx1 | 2286.0 | 4532.0 |
| Rcc1 | -11744.0 | 12735.0 |
| Rcc2 | 2405.0 | 7611.0 |
| Rfc1 | 9267.0 | -10537.0 |
| Rfc2 | -6748.0 | 11476.0 |
| Rfc3 | 13044.0 | -6703.0 |
| Rfc4 | 3874.0 | 2158.0 |
| Rfc5 | 12334.0 | 8699.0 |
| Rpa1 | -5523.0 | 11078.0 |
| Rpa2 | 6898.0 | -2423.0 |
| Rpa3 | -2462.0 | 3353.0 |
| Rps27 | 13829.0 | -14647.0 |
| Rps27a | 13894.0 | -14715.0 |
| Rrm2 | 14293.0 | -13094.0 |
| Sdccag8 | 10406.0 | -11798.0 |
| Sec13 | 9849.0 | -12486.0 |
| Seh1l | 9415.0 | -7505.0 |
| Set | -7029.0 | 5919.0 |
| Sfi1 | -8788.0 | 8246.0 |
| Sgol1 | -1679.0 | 7844.0 |
| Sgol2a | 8718.0 | -3548.0 |
| Sirt2 | 9215.0 | -457.0 |
| Ska1 | 6709.0 | -10296.0 |
| Ska2 | -9526.0 | 7541.0 |
| Skp1a | -9392.0 | 1413.0 |
| Skp2 | -9937.0 | 5846.0 |
| Smc1a | 3009.0 | -11954.0 |
| Smc2 | 194.0 | -3587.0 |
| Smc3 | 9972.0 | -12948.0 |
| Smc4 | -3258.0 | -8259.0 |
| Spast | -7791.0 | 2757.0 |
| Spc24 | 13403.0 | -11390.0 |
| Spc25 | 15273.0 | -15132.0 |
| Spdl1 | 10773.0 | -10080.0 |
| Src | 8646.0 | 4243.0 |
| Ssna1 | -6691.0 | -6655.0 |
| Stag1 | -9666.0 | 10304.0 |
| Stag2 | 2947.0 | -13895.0 |
| Sumo1 | -5337.0 | -10745.0 |
| Taok1 | -4234.0 | -10641.0 |
| Tfdp1 | -7152.0 | 7854.0 |
| Tfdp2 | 12095.0 | -12073.0 |
| Tk1 | -11584.0 | 10053.0 |
| Tmpo | -11972.0 | 12265.0 |
| Tnpo1 | 9194.0 | -10888.0 |
| Top2a | 11131.0 | -17.0 |
| Tpr | -7568.0 | -3358.0 |
| Tpx2 | 12040.0 | 4167.0 |
| Trp53 | -7681.0 | 5460.0 |
| Tuba1a | -2804.0 | -5493.0 |
| Tuba1b | 6722.0 | 5365.0 |
| Tuba4a | -4434.0 | 8186.0 |
| Tuba8 | 12324.0 | -4975.0 |
| Tubal3 | 876.5 | -1222.5 |
| Tubb1 | -3307.0 | -456.0 |
| Tubb2a | 11648.0 | -11653.0 |
| Tubb2b | 14029.0 | -12592.0 |
| Tubb3 | -1623.0 | 4178.0 |
| Tubb4a | 4305.0 | 7032.0 |
| Tubb4b | -7669.0 | 7704.0 |
| Tubb5 | 4901.0 | -6793.0 |
| Tubb6 | -9629.0 | 9882.0 |
| Tubg1 | 6654.0 | 8230.0 |
| Tubg2 | 7002.0 | 2507.0 |
| Tubgcp2 | 12709.0 | 9053.0 |
| Tubgcp3 | 10323.0 | -8943.0 |
| Tubgcp4 | -10450.0 | 8640.0 |
| Tubgcp5 | 3415.0 | -10011.0 |
| Tubgcp6 | -10196.0 | 8388.0 |
| Tyms | 7851.0 | -10098.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Ube2c | 9861.0 | -8024.0 |
| Ube2d1 | 11721.0 | -13291.0 |
| Ube2e1 | -10811.0 | 7252.0 |
| Ube2i | 13984.0 | -13775.0 |
| Ube2s | 9693.0 | -6037.0 |
| Uso1 | -8372.0 | 5238.0 |
| Vps4a | -10273.0 | 7118.0 |
| Vrk1 | -3620.0 | 7646.0 |
| Vrk2 | -4483.0 | 1847.0 |
| Wapl | -3476.0 | -10206.0 |
| Wee1 | 249.0 | -14752.0 |
| Xpo1 | -10778.0 | 9680.0 |
| Ywhae | 2275.0 | -8018.0 |
| Ywhag | -10205.0 | 10203.0 |
| Zw10 | -5911.0 | 7531.0 |
| Zwilch | 13125.0 | -12780.0 |
| Zwint | 12999.0 | -14462.0 |
Cell-Cycle
| metric | value |
|---|---|
| setSize | 603 |
| pMANOVA | 0.000123 |
| p.adjustMANOVA | 0.000811 |
| s.dist | 0.123 |
| s.diab | 0.101 |
| s.PMX | -0.071 |
| p.diab | 2.22e-05 |
| p.PMX | 0.00283 |
| Gene | diab | PMX |
|---|---|---|
| Ccnd3 | 15351 | -15060 |
| Spc25 | 15273 | -15132 |
| Nop10 | 14932 | -15027 |
| Chmp4c | 14654 | -14956 |
| Ppp2r5a | 14617 | -14818 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Rb1 | 15102 | -13818 |
| Brca1 | 14765 | -14101 |
| Optn | 15124 | -13664 |
| Cdkn2b | 14383 | -14293 |
| Rps27a | 13894 | -14715 |
| Rps27 | 13829 | -14647 |
| Nek6 | 13921 | -14431 |
| Dync1i2 | 13930 | -14334 |
| Dync1li2 | 13775 | -14349 |
| Sun2 | 14577 | -13431 |
| Golga2 | 14538 | -13457 |
| Rsf1 | 13831 | -14144 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| 1700123L14Rik | -2109.5 | 2317.5 |
| Aaas | 13184.0 | 10673.0 |
| Abl1 | 6603.0 | -4424.0 |
| Acd | -4896.0 | 9107.0 |
| Actr1a | 10383.0 | -8216.0 |
| Ahctf1 | -10865.0 | -10185.0 |
| Ajuba | -11055.0 | 10965.0 |
| Akap9 | 5910.0 | -8203.0 |
| Akt1 | 11899.0 | -4407.0 |
| Akt2 | -10282.0 | 10289.0 |
| Akt3 | -23.0 | -6307.0 |
| Alms1 | -11955.0 | 12031.0 |
| Anapc1 | -11278.0 | 10450.0 |
| Anapc10 | -40.0 | -7692.0 |
| Anapc11 | -4767.0 | -2276.0 |
| Anapc15 | -2513.0 | -9553.0 |
| Anapc16 | 13128.0 | -13447.0 |
| Anapc2 | -3217.0 | 9388.0 |
| Anapc4 | 14276.0 | -12248.0 |
| Anapc5 | 14536.0 | -12088.0 |
| Anapc7 | 10824.0 | -6183.0 |
| Ankle2 | 2982.0 | 3698.0 |
| Ankrd28 | 13265.0 | -13915.0 |
| Arpp19 | -10703.0 | 11233.0 |
| Atm | 11462.0 | 2585.0 |
| Atr | 4265.0 | -9369.0 |
| Atrip | 8548.0 | -28.0 |
| Atrx | 11763.0 | -12296.0 |
| Aurka | 12135.0 | -7881.0 |
| Aurkb | 6296.0 | -7654.0 |
| B9d2 | -5649.0 | 8837.0 |
| Babam1 | -5669.0 | 6529.0 |
| Banf1 | 9290.0 | -8382.0 |
| Bard1 | 7141.0 | -328.0 |
| Birc5 | 12522.0 | -11275.0 |
| Blm | 13734.0 | -11646.0 |
| Blzf1 | 7887.0 | -3336.0 |
| Bmyc | 6106.0 | 3479.0 |
| Bora | 10161.0 | -12351.0 |
| Brca1 | 14765.0 | -14101.0 |
| Brca2 | 12113.0 | -14047.0 |
| Brcc3 | 3410.0 | -9434.0 |
| Bre | 14292.0 | -12007.0 |
| Brip1 | 12955.0 | -13168.0 |
| Btrc | -1383.0 | 8479.0 |
| Bub1 | 7301.0 | 7957.0 |
| Bub1b | 11232.0 | 4229.0 |
| Bub3 | -11165.0 | 11759.0 |
| Cables1 | 2270.0 | 12575.0 |
| Cc2d1b | 8641.0 | 7466.0 |
| Ccna2 | 12043.0 | -6678.0 |
| Ccnb1 | 14031.0 | -8068.0 |
| Ccnb2 | 10799.0 | -9616.0 |
| Ccnd1 | 10280.0 | 12715.0 |
| Ccnd2 | -10391.0 | 11271.0 |
| Ccnd3 | 15351.0 | -15060.0 |
| Ccne1 | 8507.0 | -10924.0 |
| Ccne2 | 4837.0 | -11061.0 |
| Ccnh | -9565.0 | 9010.0 |
| Ccp110 | -3885.0 | -8946.0 |
| Cdc14a | -8389.0 | 10394.0 |
| Cdc16 | 10625.0 | -286.0 |
| Cdc20 | 13126.0 | -4714.0 |
| Cdc23 | 180.0 | 8382.0 |
| Cdc25a | 3462.0 | -12613.0 |
| Cdc25b | 8473.0 | 6982.0 |
| Cdc25c | 9859.0 | -6321.0 |
| Cdc26 | 8205.0 | -5823.0 |
| Cdc27 | -6730.0 | -6274.0 |
| Cdc45 | 8657.0 | -7688.0 |
| Cdc6 | -2324.0 | 4582.0 |
| Cdc7 | -9107.0 | 8769.0 |
| Cdca5 | 6525.0 | 30.0 |
| Cdca8 | 3238.0 | -2833.0 |
| Cdk1 | 12509.0 | -9455.0 |
| Cdk11b | 10589.0 | -10741.0 |
| Cdk2 | 12902.0 | -12285.0 |
| Cdk4 | 7497.0 | 6438.0 |
| Cdk5rap2 | -7137.0 | 3897.0 |
| Cdk6 | -8022.0 | -8784.0 |
| Cdk7 | -6948.0 | 4688.0 |
| Cdkn1a | 15394.0 | -12557.0 |
| Cdkn1b | 4380.0 | 258.0 |
| Cdkn1c | 11412.0 | 12041.0 |
| Cdkn2b | 14383.0 | -14293.0 |
| Cdkn2c | -1158.0 | 9132.0 |
| Cdkn2d | 5293.0 | 2129.0 |
| Cdt1 | 8222.0 | -9768.0 |
| Cenpa | 3435.0 | 5318.0 |
| Cenpc1 | -3272.0 | -8022.0 |
| Cenpe | 4365.0 | -6647.0 |
| Cenpf | 13427.0 | -379.0 |
| Cenph | 10433.0 | -9250.0 |
| Cenpi | 8123.0 | -7481.0 |
| Cenpj | -11728.0 | 6522.0 |
| Cenpk | 9317.0 | -8016.0 |
| Cenpl | -1784.0 | -10457.0 |
| Cenpm | 11559.0 | -9488.0 |
| Cenpn | 9068.0 | 4694.0 |
| Cenpo | 4588.0 | -8699.0 |
| Cenpp | 5610.0 | 4078.0 |
| Cenpq | -8830.0 | -3341.0 |
| Cenpt | 13110.0 | -10179.0 |
| Cenpu | 11737.0 | -7832.0 |
| Cenpw | 10269.0 | -7741.0 |
| Cep131 | 11325.0 | -5598.0 |
| Cep135 | -3810.0 | 8621.0 |
| Cep152 | -1773.0 | 196.0 |
| Cep164 | 8128.0 | 5691.0 |
| Cep192 | 52.0 | 8736.0 |
| Cep250 | -3793.0 | 9525.0 |
| Cep290 | -10441.0 | 11686.0 |
| Cep41 | -10073.0 | 11800.0 |
| Cep57 | 8021.0 | -13087.0 |
| Cep63 | -3404.0 | -10352.0 |
| Cep70 | 12768.0 | 392.0 |
| Cep72 | 8804.0 | 5042.0 |
| Cep76 | -5040.0 | 5787.0 |
| Cep78 | -9622.0 | 4307.0 |
| Cetn2 | -9237.0 | 3491.0 |
| Chek1 | 10916.0 | -6645.0 |
| Chek2 | -5693.0 | 11236.0 |
| Chmp2a | 6531.0 | -8482.0 |
| Chmp2b | 11049.0 | -9912.0 |
| Chmp3 | 8777.0 | -13102.0 |
| Chmp4b | 13369.0 | -13601.0 |
| Chmp4c | 14654.0 | -14956.0 |
| Chmp6 | 9126.0 | 9611.0 |
| Chmp7 | -7612.0 | 12648.0 |
| Chtf18 | -999.0 | 5623.0 |
| Chtf8 | -11988.0 | 12646.0 |
| Ckap5 | -1941.0 | 9831.0 |
| Cks1b | 12264.0 | -6528.0 |
| Clasp1 | 8043.0 | -6017.0 |
| Clasp2 | 14039.0 | -9470.0 |
| Clip1 | -3196.0 | -4018.0 |
| Clspn | -4322.0 | 6551.0 |
| Cnep1r1 | 4530.0 | -11794.0 |
| Cntrl | 10308.0 | -9086.0 |
| Csnk1d | 4297.0 | -10796.0 |
| Csnk1e | 10966.0 | -7406.0 |
| Csnk2a1 | 111.0 | -6883.0 |
| Csnk2a2 | 4776.0 | -8371.0 |
| Csnk2b | 4564.0 | -136.0 |
| Ctc1 | 8890.0 | 4858.0 |
| Ctdnep1 | -10262.0 | 11004.0 |
| Cul1 | 114.0 | -11623.0 |
| Daxx | -6696.0 | 7271.0 |
| Dbf4 | 11748.0 | -11992.0 |
| Dctn1 | 4613.0 | 8656.0 |
| Dctn2 | 13574.0 | -8129.0 |
| Dctn3 | 13985.0 | -13682.0 |
| Dhfr | -11741.0 | 10911.0 |
| Dido1 | -9774.0 | -9656.0 |
| Dkc1 | -9010.0 | 7070.0 |
| Dmc1 | 10141.0 | 1641.0 |
| Dna2 | -7971.0 | 5856.0 |
| Dscc1 | 9583.0 | -5359.0 |
| Dsn1 | 12989.0 | -13118.0 |
| Dync1h1 | 12037.0 | 3704.0 |
| Dync1i1 | 7564.0 | 7503.0 |
| Dync1i2 | 13930.0 | -14334.0 |
| Dync1li1 | 10870.0 | -10085.0 |
| Dync1li2 | 13775.0 | -14349.0 |
| Dynll1 | -10023.0 | -2241.0 |
| Dynll2 | -12351.0 | 10871.0 |
| Dyrk1a | 6379.0 | -5909.0 |
| E2f1 | 14773.0 | -13127.0 |
| E2f2 | -10922.0 | 8773.0 |
| E2f3 | 9873.0 | 3869.0 |
| E2f4 | -8258.0 | 5909.0 |
| E2f5 | -12272.0 | 11795.0 |
| E2f6 | -11558.0 | 12122.0 |
| Emd | 9167.0 | -10589.0 |
| Eml4 | 398.0 | 4690.0 |
| Ensa | 4482.0 | -12626.0 |
| Ep300 | -10091.0 | 9600.0 |
| Ercc6l | -7435.0 | 2783.0 |
| Esco1 | -6644.0 | 1090.0 |
| Esco2 | 11918.0 | -9481.0 |
| Espl1 | 7494.0 | -361.0 |
| Exo1 | 11044.0 | -10136.0 |
| Fam175a | 6799.0 | 4765.0 |
| Fbxl18 | -8136.0 | 9051.0 |
| Fbxl7 | -276.0 | 7460.0 |
| Fbxo5 | -1870.0 | 5491.0 |
| Fbxw11 | -10435.0 | 9702.0 |
| Fen1 | 7543.0 | 234.0 |
| Fkbp6 | 4694.5 | -4905.0 |
| Fkbpl | -5916.0 | 4598.0 |
| Foxm1 | 12715.0 | -5772.0 |
| Fzr1 | -2715.0 | 9851.0 |
| Gar1 | -5704.0 | -2440.0 |
| Gins1 | -4499.0 | 1259.0 |
| Gins2 | 14037.0 | -12388.0 |
| Gins3 | -2737.0 | -3111.0 |
| Gins4 | 6658.0 | -4395.0 |
| Gmnn | 12869.0 | -13700.0 |
| Golga2 | 14538.0 | -13457.0 |
| Gorasp1 | -11150.0 | 12579.0 |
| Gorasp2 | 2975.0 | 3355.0 |
| Gsk3b | -6315.0 | 7700.0 |
| Gtse1 | 14189.0 | 5321.0 |
| H2afx | -3852.0 | 6424.0 |
| Haus1 | 9580.0 | -4996.0 |
| Haus2 | -1376.0 | -9517.0 |
| Haus3 | 12682.0 | -12876.0 |
| Haus4 | 13772.0 | -8411.0 |
| Haus5 | 3099.0 | 5247.0 |
| Haus6 | -4075.0 | -11789.0 |
| Haus7 | 14036.0 | -9664.0 |
| Haus8 | 9204.0 | 3914.0 |
| Hdac1 | -10878.0 | 10117.0 |
| Hdac8 | 5664.0 | -6069.0 |
| Herc2 | -7744.0 | 11170.0 |
| Hjurp | -9582.0 | 11276.0 |
| Hmmr | 13358.0 | -11832.0 |
| Hsp90aa1 | -12505.0 | 4614.0 |
| Hsp90ab1 | -12580.0 | 11764.0 |
| Hspa2 | 14737.0 | -9848.0 |
| Hus1 | -10726.0 | 1804.0 |
| Incenp | 5723.0 | -3327.0 |
| Ist1 | 8650.0 | 5536.0 |
| Itgb3bp | 4897.0 | -8304.0 |
| Jak2 | -8549.0 | -13401.0 |
| Kat5 | 4420.0 | 6683.0 |
| Kif18a | -3219.0 | -3152.0 |
| Kif20a | 13428.0 | -4447.0 |
| Kif23 | 14225.0 | -12979.0 |
| Kif2a | 11818.0 | -4454.0 |
| Kif2c | 10981.0 | -8403.0 |
| Kmt5a | 5653.0 | 6397.0 |
| Kntc1 | 11653.0 | -11626.0 |
| Kpnb1 | 10908.0 | 1199.0 |
| Lbr | -12455.0 | 12869.0 |
| Lcmt1 | 13397.0 | -7684.0 |
| Lemd2 | 4754.0 | 6810.0 |
| Lemd3 | 2945.0 | -5014.0 |
| Lig1 | 13161.0 | -4756.0 |
| Lin37 | -7391.0 | 6267.0 |
| Lin52 | 9562.0 | -7056.0 |
| Lin54 | -5778.0 | 5287.0 |
| Lin9 | 7699.0 | -11842.0 |
| Lmna | 5606.0 | 3857.0 |
| Lmnb1 | -9916.0 | 8126.0 |
| Lpin1 | 13638.0 | -14073.0 |
| Lpin2 | 12674.0 | -14612.0 |
| Lpin3 | 14358.0 | -8350.0 |
| Lyn | -7639.0 | 6.0 |
| Mad1l1 | -2336.0 | 6065.0 |
| Mad2l1 | 12617.0 | -8263.0 |
| Mapk1 | 6867.0 | -10406.0 |
| Mapk3 | 10588.0 | -6813.0 |
| Mapre1 | 3104.0 | 2535.0 |
| Mastl | 9321.0 | -5732.0 |
| Mau2 | 13230.0 | -13597.0 |
| Max | 13684.0 | -12344.0 |
| Mcm10 | 3403.0 | 4685.0 |
| Mcm2 | -1041.0 | 10178.0 |
| Mcm3 | 3215.0 | 4597.0 |
| Mcm4 | -1878.0 | -3408.0 |
| Mcm5 | -4271.0 | 7491.0 |
| Mcm6 | 5041.0 | 5685.0 |
| Mcm7 | 6463.0 | 7251.0 |
| Mcm8 | 11218.0 | -4422.0 |
| Mcph1 | 8663.0 | -388.0 |
| Mdc1 | -4783.0 | 9438.0 |
| Mdm2 | 15095.0 | -7329.0 |
| Mdm4 | -4386.0 | -13416.0 |
| Mis12 | -8150.0 | 7697.0 |
| Mis18a | 5424.0 | -6523.0 |
| Mis18bp1 | 10046.0 | -3755.0 |
| Mlh1 | -6045.0 | 6377.0 |
| Mlh3 | -10415.0 | 11077.0 |
| Mnat1 | 5792.0 | 4333.0 |
| Mnd1 | -10696.0 | 5540.0 |
| Mre11a | -5960.0 | 7726.0 |
| Msh4 | 11993.0 | -8386.0 |
| Msh5 | 12959.0 | -11537.0 |
| Mybl2 | 11695.0 | -13356.0 |
| Mzt1 | 10494.0 | -12063.0 |
| Mzt2 | 10538.0 | -7815.0 |
| Nbn | -7224.0 | -4610.0 |
| Ncapd2 | 10711.0 | -105.0 |
| Ncapd3 | 11681.0 | -13198.0 |
| Ncapg | 8006.0 | 5170.0 |
| Ncapg2 | 13407.0 | -8517.0 |
| Ncaph | 9662.0 | -7763.0 |
| Ncaph2 | 4224.0 | 91.0 |
| Ndc1 | 13238.0 | -12109.0 |
| Ndc80 | 11305.0 | -7543.0 |
| Nde1 | -6074.0 | 8864.0 |
| Ndel1 | -6462.0 | -13712.0 |
| Nedd1 | -5802.0 | -9203.0 |
| Nek2 | 14119.0 | -11365.0 |
| Nek6 | 13921.0 | -14431.0 |
| Nek7 | -8839.0 | 7258.0 |
| Nek9 | -8705.0 | 11327.0 |
| Nhp2 | -4543.0 | -7331.0 |
| Ninl | 12966.0 | -10855.0 |
| Nipbl | -7169.0 | -3159.0 |
| Nme7 | -10054.0 | 6679.0 |
| Nop10 | 14932.0 | -15027.0 |
| Nsl1 | 2968.0 | 2930.0 |
| Nudc | 9181.0 | -10432.0 |
| Nuf2 | 8710.0 | -9737.0 |
| Numa1 | -6029.0 | 10210.0 |
| Nup107 | -4524.0 | -6225.0 |
| Nup133 | -6405.0 | 10731.0 |
| Nup153 | -10729.0 | 9979.0 |
| Nup155 | 11046.0 | -12223.0 |
| Nup160 | -7196.0 | -7326.0 |
| Nup188 | -6119.0 | 7249.0 |
| Nup205 | 5816.0 | 3749.0 |
| Nup210 | 14542.0 | -63.0 |
| Nup214 | 13088.0 | -10974.0 |
| Nup35 | -8231.0 | 10983.0 |
| Nup37 | -4813.0 | 9951.0 |
| Nup43 | 8894.0 | -8868.0 |
| Nup54 | -6950.0 | 2963.0 |
| Nup62 | -8836.0 | 8004.0 |
| Nup85 | -9207.0 | 9918.0 |
| Nup88 | 14341.0 | -12858.0 |
| Nup93 | 12551.0 | 5537.0 |
| Nup98 | 10837.0 | 4406.0 |
| Nupl1 | 11303.0 | -7772.0 |
| Obfc1 | 10962.0 | 1945.0 |
| Odf2 | 12329.0 | -8688.0 |
| Ofd1 | 12344.0 | -10416.0 |
| Oip5 | 10805.0 | -8534.0 |
| Optn | 15124.0 | -13664.0 |
| Orc1 | 9734.0 | -7991.0 |
| Orc2 | 2889.0 | -9894.0 |
| Orc3 | -4717.0 | 3382.0 |
| Orc4 | -5269.0 | -2439.0 |
| Orc5 | 10597.0 | -8072.0 |
| Orc6 | 374.0 | -7010.0 |
| Pafah1b1 | 4117.0 | -10743.0 |
| Pcbp4 | -10989.0 | 12360.0 |
| Pcm1 | 11605.0 | -13363.0 |
| Pcna | 13367.0 | -14114.0 |
| Pcnt | 11489.0 | -8081.0 |
| Pds5a | -2274.0 | -8133.0 |
| Pds5b | -8117.0 | 11104.0 |
| Phf20 | 12053.0 | -14031.0 |
| Phf8 | -1381.0 | -4659.0 |
| Phlda1 | -8040.0 | 9959.0 |
| Pias4 | -9679.0 | 8206.0 |
| Pif1 | 7985.0 | -7316.0 |
| Pkmyt1 | 10003.0 | -8959.0 |
| Plk1 | 9395.0 | -5777.0 |
| Plk4 | 2268.0 | -7402.0 |
| Pmf1 | 13680.0 | -10495.0 |
| Pola1 | -8880.0 | 5777.0 |
| Pola2 | 8004.0 | -5681.0 |
| Pold1 | 5255.0 | 4543.0 |
| Pold2 | 12631.0 | -8485.0 |
| Pold3 | -4233.0 | 6741.0 |
| Pold4 | 7034.0 | -12051.0 |
| Pole | 11606.0 | -7660.0 |
| Pole2 | -7143.0 | -143.0 |
| Pole3 | 10431.0 | -13031.0 |
| Pole4 | -11603.0 | 7992.0 |
| Polr2a | 5917.0 | 6827.0 |
| Polr2b | -9995.0 | 7496.0 |
| Polr2c | -2600.0 | 9289.0 |
| Polr2d | -4100.0 | 39.0 |
| Polr2e | 11726.0 | -9159.0 |
| Polr2f | 11374.0 | -6543.0 |
| Polr2g | 11118.0 | -13257.0 |
| Polr2h | 224.0 | -7426.0 |
| Polr2i | 13554.0 | -12640.0 |
| Polr2j | 9902.0 | -6099.0 |
| Polr2k | 7520.0 | -11503.0 |
| Polr2l | 6213.0 | 4463.0 |
| Pom121 | 9659.0 | -12785.0 |
| Pot1a | -4539.0 | 2798.0 |
| Ppme1 | 3702.0 | 3.0 |
| Ppp1cb | 4565.0 | -10643.0 |
| Ppp1cc | 13589.0 | -11988.0 |
| Ppp1r12a | 3470.0 | -9878.0 |
| Ppp1r12b | -7715.0 | 11767.0 |
| Ppp2ca | 2443.0 | 326.0 |
| Ppp2cb | 14291.0 | -13381.0 |
| Ppp2r1a | 11507.0 | 3755.0 |
| Ppp2r1b | -3062.0 | -7202.0 |
| Ppp2r2a | -1142.0 | -9444.0 |
| Ppp2r2d | 12749.0 | -14570.0 |
| Ppp2r3d | -3033.0 | 6807.0 |
| Ppp2r5a | 14617.0 | -14818.0 |
| Ppp2r5b | -2576.0 | 4479.0 |
| Ppp2r5c | 12442.0 | -9365.0 |
| Ppp2r5d | 11554.0 | 1834.0 |
| Ppp2r5e | -4849.0 | 4842.0 |
| Ppp6c | 5727.0 | -12586.0 |
| Ppp6r3 | -10825.0 | 11674.0 |
| Prdm9 | -4544.0 | -5660.0 |
| Prim1 | -8624.0 | 10425.0 |
| Prim2 | -9097.0 | 5742.0 |
| Prkar2b | -11024.0 | 2146.0 |
| Prkca | -11577.0 | 11021.0 |
| Prkcb | -7742.0 | 7077.0 |
| Psma1 | -6738.0 | -7608.0 |
| Psma2 | 2844.0 | -13370.0 |
| Psma3 | 9490.0 | -12548.0 |
| Psma4 | 4617.0 | -12505.0 |
| Psma5 | 5504.0 | -11202.0 |
| Psma6 | 9985.0 | -12478.0 |
| Psma7 | 13781.0 | -14022.0 |
| Psma8 | -7575.0 | 7041.0 |
| Psmb1 | 6104.0 | -12225.0 |
| Psmb10 | 8202.0 | -4783.0 |
| Psmb11 | 5872.0 | -6129.0 |
| Psmb2 | 7847.0 | -11836.0 |
| Psmb3 | 12063.0 | -13952.0 |
| Psmb4 | -4466.0 | -8497.0 |
| Psmb5 | 10041.0 | -10541.0 |
| Psmb6 | 11789.0 | -12835.0 |
| Psmb7 | 175.0 | -13055.0 |
| Psmb8 | -5795.0 | 2962.0 |
| Psmb9 | -3858.0 | 5687.0 |
| Psmc1 | 11705.0 | -6393.0 |
| Psmc2 | -10211.0 | 7777.0 |
| Psmc3 | 13783.0 | -13466.0 |
| Psmc3ip | -8272.0 | 1931.0 |
| Psmc4 | -7487.0 | 10029.0 |
| Psmc5 | 5939.0 | -5097.0 |
| Psmc6 | -5320.0 | -12074.0 |
| Psmd1 | -4486.0 | -6816.0 |
| Psmd10 | -5266.0 | 7738.0 |
| Psmd11 | -4239.0 | -7981.0 |
| Psmd12 | -5190.0 | -6195.0 |
| Psmd13 | 10924.0 | -7634.0 |
| Psmd14 | -9498.0 | 2769.0 |
| Psmd2 | -11276.0 | 10253.0 |
| Psmd3 | 5369.0 | 146.0 |
| Psmd4 | 8666.0 | -10398.0 |
| Psmd5 | -1595.0 | -6026.0 |
| Psmd6 | -1663.0 | -8390.0 |
| Psmd7 | -9175.0 | -8611.0 |
| Psmd8 | 14709.0 | -14720.0 |
| Psmd9 | 14751.0 | -14675.0 |
| Psme1 | 14335.0 | -14654.0 |
| Psme2b | 158.0 | 1873.0 |
| Psme3 | -3827.0 | 9126.0 |
| Psme4 | -4545.0 | -7955.0 |
| Psmf1 | 3006.0 | 8610.0 |
| Ptk6 | -8916.0 | 7487.0 |
| Pttg1 | 13199.0 | -11759.0 |
| Rab1a | -8474.0 | 2511.0 |
| Rab1b | -6847.0 | 3621.0 |
| Rab2a | -8200.0 | -6726.0 |
| Rab8a | -7413.0 | -3395.0 |
| Rad1 | -6955.0 | 4321.0 |
| Rad17 | 226.0 | -6799.0 |
| Rad21 | -6091.0 | -9748.0 |
| Rad50 | 9654.0 | -3235.0 |
| Rad51 | 9950.0 | -249.0 |
| Rad51c | -11332.0 | 10034.0 |
| Rad9a | 8550.0 | 4566.0 |
| Rad9b | 6251.0 | -7308.0 |
| Rae1 | -2818.0 | 7959.0 |
| Ran | -340.0 | -458.0 |
| Ranbp2 | -1884.0 | -9227.0 |
| Rangap1 | -4113.0 | 2101.0 |
| Rb1 | 15102.0 | -13818.0 |
| Rbbp4 | -12462.0 | 12126.0 |
| Rbbp7 | 225.0 | -7926.0 |
| Rbbp8 | 13717.0 | -12966.0 |
| Rbl1 | -9375.0 | 11563.0 |
| Rbl2 | 11787.0 | -7420.0 |
| Rbx1 | 2286.0 | 4532.0 |
| Rcc1 | -11744.0 | 12735.0 |
| Rcc2 | 2405.0 | 7611.0 |
| Rec8 | 13624.0 | 8232.0 |
| Rfc1 | 9267.0 | -10537.0 |
| Rfc2 | -6748.0 | 11476.0 |
| Rfc3 | 13044.0 | -6703.0 |
| Rfc4 | 3874.0 | 2158.0 |
| Rfc5 | 12334.0 | 8699.0 |
| Rfwd2 | -2988.0 | -5509.0 |
| Rhno1 | 7419.0 | -5059.0 |
| Rmi1 | -9220.0 | 10169.0 |
| Rmi2 | 9282.0 | 3955.0 |
| Rnf168 | -4091.0 | -149.0 |
| Rnf8 | -2987.0 | -6982.0 |
| Rpa1 | -5523.0 | 11078.0 |
| Rpa2 | 6898.0 | -2423.0 |
| Rpa3 | -2462.0 | 3353.0 |
| Rps27 | 13829.0 | -14647.0 |
| Rps27a | 13894.0 | -14715.0 |
| Rrm2 | 14293.0 | -13094.0 |
| Rsf1 | 13831.0 | -14144.0 |
| Rtel1 | 5442.0 | 9777.0 |
| Ruvbl1 | -5892.0 | 8551.0 |
| Ruvbl2 | -9067.0 | 7462.0 |
| Sdccag8 | 10406.0 | -11798.0 |
| Sec13 | 9849.0 | -12486.0 |
| Seh1l | 9415.0 | -7505.0 |
| Set | -7029.0 | 5919.0 |
| Sfi1 | -8788.0 | 8246.0 |
| Sfn | 9301.0 | 71.0 |
| Sgol1 | -1679.0 | 7844.0 |
| Sgol2a | 8718.0 | -3548.0 |
| Shq1 | -5132.0 | -3585.0 |
| Sirt2 | 9215.0 | -457.0 |
| Ska1 | 6709.0 | -10296.0 |
| Ska2 | -9526.0 | 7541.0 |
| Skp1a | -9392.0 | 1413.0 |
| Skp2 | -9937.0 | 5846.0 |
| Smarca5 | -10192.0 | 3369.0 |
| Smc1a | 3009.0 | -11954.0 |
| Smc1b | -377.5 | 2676.0 |
| Smc2 | 194.0 | -3587.0 |
| Smc3 | 9972.0 | -12948.0 |
| Smc4 | -3258.0 | -8259.0 |
| Spast | -7791.0 | 2757.0 |
| Spc24 | 13403.0 | -11390.0 |
| Spc25 | 15273.0 | -15132.0 |
| Spdl1 | 10773.0 | -10080.0 |
| Spo11 | -8743.0 | 11358.0 |
| Src | 8646.0 | 4243.0 |
| Ssna1 | -6691.0 | -6655.0 |
| Stag1 | -9666.0 | 10304.0 |
| Stag2 | 2947.0 | -13895.0 |
| Stag3 | -10429.0 | 8496.0 |
| Sumo1 | -5337.0 | -10745.0 |
| Sun1 | 5347.0 | 8326.0 |
| Sun2 | 14577.0 | -13431.0 |
| Syce1 | 8655.0 | -2386.0 |
| Syce2 | 12391.0 | -6751.0 |
| Sycp2 | -8183.0 | 6602.0 |
| Sycp3 | -8114.0 | 7074.0 |
| Syne2 | -7818.0 | -7089.0 |
| Taok1 | -4234.0 | -10641.0 |
| Ten1 | -7854.0 | -8245.0 |
| Terf1 | -3395.0 | -5560.0 |
| Terf2 | -15.0 | -5815.0 |
| Terf2ip | -6777.0 | 9210.0 |
| Tert | 13272.0 | 17.0 |
| Tex12 | -2109.5 | 2317.5 |
| Tex15 | 14085.0 | -4780.0 |
| Tfdp1 | -7152.0 | 7854.0 |
| Tfdp2 | 12095.0 | -12073.0 |
| Tinf2 | 6319.0 | -3531.0 |
| Tk1 | -11584.0 | 10053.0 |
| Tmpo | -11972.0 | 12265.0 |
| Tnpo1 | 9194.0 | -10888.0 |
| Top2a | 11131.0 | -17.0 |
| Top3a | -8478.0 | -5110.0 |
| Topbp1 | 4504.0 | -5842.0 |
| Tpr | -7568.0 | -3358.0 |
| Tpx2 | 12040.0 | 4167.0 |
| Trp53 | -7681.0 | 5460.0 |
| Trp53bp1 | -9861.0 | 10372.0 |
| Tuba1a | -2804.0 | -5493.0 |
| Tuba1b | 6722.0 | 5365.0 |
| Tuba4a | -4434.0 | 8186.0 |
| Tuba8 | 12324.0 | -4975.0 |
| Tubal3 | 876.5 | -1222.5 |
| Tubb1 | -3307.0 | -456.0 |
| Tubb2a | 11648.0 | -11653.0 |
| Tubb2b | 14029.0 | -12592.0 |
| Tubb3 | -1623.0 | 4178.0 |
| Tubb4a | 4305.0 | 7032.0 |
| Tubb4b | -7669.0 | 7704.0 |
| Tubb5 | 4901.0 | -6793.0 |
| Tubb6 | -9629.0 | 9882.0 |
| Tubg1 | 6654.0 | 8230.0 |
| Tubg2 | 7002.0 | 2507.0 |
| Tubgcp2 | 12709.0 | 9053.0 |
| Tubgcp3 | 10323.0 | -8943.0 |
| Tubgcp4 | -10450.0 | 8640.0 |
| Tubgcp5 | 3415.0 | -10011.0 |
| Tubgcp6 | -10196.0 | 8388.0 |
| Tyms | 7851.0 | -10098.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Ube2c | 9861.0 | -8024.0 |
| Ube2d1 | 11721.0 | -13291.0 |
| Ube2e1 | -10811.0 | 7252.0 |
| Ube2i | 13984.0 | -13775.0 |
| Ube2s | 9693.0 | -6037.0 |
| Ube2v2 | -8928.0 | 4163.0 |
| Uimc1 | -4365.0 | 352.0 |
| Uso1 | -8372.0 | 5238.0 |
| Vps4a | -10273.0 | 7118.0 |
| Vrk1 | -3620.0 | 7646.0 |
| Vrk2 | -4483.0 | 1847.0 |
| Wapl | -3476.0 | -10206.0 |
| Wee1 | 249.0 | -14752.0 |
| Wrap53 | -6869.0 | 11009.0 |
| Wrn | -3128.0 | 5665.0 |
| Xpo1 | -10778.0 | 9680.0 |
| Ywhab | -3531.0 | -52.0 |
| Ywhae | 2275.0 | -8018.0 |
| Ywhag | -10205.0 | 10203.0 |
| Ywhah | 3055.0 | -11126.0 |
| Ywhaq | 12431.0 | -12558.0 |
| Zfp385a | 15036.0 | -8764.0 |
| Zw10 | -5911.0 | 7531.0 |
| Zwilch | 13125.0 | -12780.0 |
| Zwint | 12999.0 | -14462.0 |
Integrin-cell-surface-interactions
| metric | value |
|---|---|
| setSize | 64 |
| pMANOVA | 0.00076 |
| p.adjustMANOVA | 0.00437 |
| s.dist | 0.251 |
| s.diab | -0.0697 |
| s.PMX | 0.241 |
| p.diab | 0.335 |
| p.PMX | 0.000862 |
| Gene | diab | PMX |
|---|---|---|
| Kdr | -12645 | 12884 |
| Itgax | -12597 | 12908 |
| Itgb7 | -12362 | 12913 |
| Itga9 | -12089 | 12867 |
| Itgb6 | -12023 | 12923 |
| Itgal | -11771 | 12813 |
| Jam3 | -11372 | 12730 |
| Col16a1 | -12297 | 11347 |
| Cd44 | -11921 | 11492 |
| Itga4 | -10182 | 12732 |
| Icam2 | -10654 | 12128 |
| Col4a4 | -10655 | 12060 |
| Hspg2 | -9709 | 12765 |
| Pecam1 | -9053 | 12320 |
| Itga8 | -9554 | 11089 |
| Vcam1 | -10545 | 8429 |
| Col4a3 | -8719 | 8992 |
| Col9a3 | -7324 | 5896 |
| Itgam | -8058 | 4871 |
| Icam5 | -4768 | 7615 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Agrn | -2557.0 | 10075.0 |
| Bsg | 10831.0 | -9772.0 |
| Cd44 | -11921.0 | 11492.0 |
| Cd47 | -5391.0 | -2458.0 |
| Cdh1 | -174.0 | 12292.0 |
| Col13a1 | 13283.0 | -13105.0 |
| Col16a1 | -12297.0 | 11347.0 |
| Col18a1 | 12226.0 | 5466.0 |
| Col23a1 | 6766.0 | -9684.0 |
| Col4a1 | 5904.0 | 7644.0 |
| Col4a2 | 12342.0 | 7010.0 |
| Col4a3 | -8719.0 | 8992.0 |
| Col4a4 | -10655.0 | 12060.0 |
| Col9a1 | -1304.5 | 3868.0 |
| Col9a2 | 4094.0 | 1499.0 |
| Col9a3 | -7324.0 | 5896.0 |
| Comp | 13019.0 | -12258.0 |
| F11r | 11089.0 | -13222.0 |
| Fbn1 | -1557.0 | 11139.0 |
| Fga | 14188.0 | -14645.0 |
| Fgb | 13155.0 | -10094.0 |
| Fgg | 14936.0 | -14182.0 |
| Fn1 | 12346.0 | 6126.0 |
| Hspg2 | -9709.0 | 12765.0 |
| Icam1 | 12408.0 | -14411.0 |
| Icam2 | -10654.0 | 12128.0 |
| Icam4 | -187.0 | 1799.0 |
| Icam5 | -4768.0 | 7615.0 |
| Itga1 | 9086.0 | 6502.0 |
| Itga10 | -7763.0 | -6633.0 |
| Itga11 | 11456.0 | 11485.0 |
| Itga2 | 7236.0 | -6041.0 |
| Itga2b | 4836.0 | -5064.0 |
| Itga3 | 9099.0 | 6566.0 |
| Itga4 | -10182.0 | 12732.0 |
| Itga5 | -6316.0 | 4295.0 |
| Itga6 | 10749.0 | -2876.0 |
| Itga7 | 11604.0 | -4725.0 |
| Itga8 | -9554.0 | 11089.0 |
| Itga9 | -12089.0 | 12867.0 |
| Itgad | -3776.0 | 1513.5 |
| Itgae | -4002.0 | 8879.0 |
| Itgal | -11771.0 | 12813.0 |
| Itgam | -8058.0 | 4871.0 |
| Itgav | 14776.0 | -14797.0 |
| Itgax | -12597.0 | 12908.0 |
| Itgb1 | 5869.0 | -13098.0 |
| Itgb2l | 4949.0 | -3001.0 |
| Itgb3 | 12310.0 | -13769.0 |
| Itgb5 | 3113.0 | 12053.0 |
| Itgb6 | -12023.0 | 12923.0 |
| Itgb7 | -12362.0 | 12913.0 |
| Itgb8 | -8645.0 | -5178.0 |
| Jam2 | -8656.0 | -7659.0 |
| Jam3 | -11372.0 | 12730.0 |
| Kdr | -12645.0 | 12884.0 |
| Lum | -2412.0 | 11141.0 |
| Madcam1 | 4094.0 | -2795.0 |
| Pecam1 | -9053.0 | 12320.0 |
| Spp1 | 15190.0 | -14758.0 |
| Thbs1 | 4377.0 | 10927.0 |
| Tnc | 5679.0 | 9966.0 |
| Vcam1 | -10545.0 | 8429.0 |
| Vtn | -9042.0 | -9360.0 |
Signaling-by-the-B-Cell-Receptor-(BCR)
| metric | value |
|---|---|
| setSize | 120 |
| pMANOVA | 0.00266 |
| p.adjustMANOVA | 0.0136 |
| s.dist | 0.102 |
| s.diab | -0.0658 |
| s.PMX | -0.0785 |
| p.diab | 0.213 |
| p.PMX | 0.137 |
| Gene | diab | PMX |
|---|---|---|
| Psmd7 | -9175 | -8611 |
| Chuk | -8103 | -8635 |
| Psmc6 | -5320 | -12074 |
| Psma1 | -6738 | -7608 |
| Rasgrp1 | -3739 | -13175 |
| Nck1 | -4016 | -10473 |
| Psmb4 | -4466 | -8497 |
| Psme4 | -4545 | -7955 |
| Psmd11 | -4239 | -7981 |
| Trpc1 | -6951 | -4789 |
| Psmd12 | -5190 | -6195 |
| Ighv14-1 | -4909 | -6534 |
| Psmd1 | -4486 | -6816 |
| Ubb | -3411 | -7959 |
| Dapp1 | -3460 | -6642 |
| Nfatc1 | -2618 | -8153 |
| Ikbkb | -1527 | -10168 |
| Psmd6 | -1663 | -8390 |
| Psmd5 | -1595 | -6026 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ahcyl1 | 6832.0 | -14545.0 |
| Bcl10 | -5706.0 | 6387.0 |
| Blk | 3046.0 | 7612.0 |
| Blnk | 14946.0 | -14514.0 |
| Btk | -6343.0 | 9675.0 |
| Btrc | -1383.0 | 8479.0 |
| Calm1 | 152.0 | -11443.0 |
| Card11 | -7798.0 | 11685.0 |
| Cd19 | -7122.0 | 7102.0 |
| Cd22 | -11312.0 | 11195.0 |
| Cd79a | -11203.0 | 8822.0 |
| Cd79b | -10852.0 | 12150.0 |
| Chuk | -8103.0 | -8635.0 |
| Cul1 | 114.0 | -11623.0 |
| Dapp1 | -3460.0 | -6642.0 |
| Fbxw11 | -10435.0 | 9702.0 |
| Fkbp1a | -4088.0 | 2763.0 |
| Fyn | -6985.0 | 9856.0 |
| Grb2 | 8972.0 | 3406.0 |
| Hras | 12615.0 | -11955.0 |
| Ighd | -11252.0 | 12232.0 |
| Ighm | -9802.0 | 12152.0 |
| Ighv14-1 | -4909.0 | -6534.0 |
| Ighv3-1 | -3456.5 | 2317.5 |
| Ighv5-4 | -8748.0 | 6914.0 |
| Ighv9-1 | -5234.0 | 4881.0 |
| Igkc | -12203.0 | 11173.0 |
| Igkv1-135 | -9391.0 | 12146.0 |
| Igkv14-130 | -3167.5 | 2317.5 |
| Igkv17-127 | -10984.0 | 6315.0 |
| Igkv2-137 | 6752.0 | -10319.0 |
| Igll1 | 11837.0 | -7314.0 |
| Ikbkb | -1527.0 | -10168.0 |
| Ikbkg | 12618.0 | -11493.0 |
| Itpr1 | 10796.0 | -11700.0 |
| Itpr2 | 13551.0 | 7710.0 |
| Itpr3 | 11003.0 | 2102.0 |
| Kras | 8243.0 | -12396.0 |
| Lyn | -7639.0 | 6.0 |
| Malt1 | -6834.0 | 10147.0 |
| Map3k7 | 10607.0 | -11166.0 |
| Nck1 | -4016.0 | -10473.0 |
| Nfatc1 | -2618.0 | -8153.0 |
| Nfatc2 | 9333.0 | 9956.0 |
| Nfatc3 | -9186.0 | 3699.0 |
| Nfkb1 | 234.0 | 10216.0 |
| Nfkbia | 14941.0 | -14953.0 |
| Nfkbib | 12056.0 | -11601.0 |
| Nfkbie | -7903.0 | 8218.0 |
| Nras | 11707.0 | -12390.0 |
| Orai1 | -6072.0 | 1991.0 |
| Orai2 | 10183.0 | -2454.0 |
| Pik3ap1 | -9717.0 | 10026.0 |
| Pik3cd | -8249.0 | 9542.0 |
| Pik3r1 | -5226.0 | 4551.0 |
| Plcg2 | -2480.0 | 12667.0 |
| Ppia | 14608.0 | -14924.0 |
| Ppp3ca | 12376.0 | -9089.0 |
| Ppp3cb | -6472.0 | 4604.0 |
| Ppp3r1 | 8691.0 | -9297.0 |
| Prkcb | -7742.0 | 7077.0 |
| Psma1 | -6738.0 | -7608.0 |
| Psma2 | 2844.0 | -13370.0 |
| Psma3 | 9490.0 | -12548.0 |
| Psma4 | 4617.0 | -12505.0 |
| Psma5 | 5504.0 | -11202.0 |
| Psma6 | 9985.0 | -12478.0 |
| Psma7 | 13781.0 | -14022.0 |
| Psma8 | -7575.0 | 7041.0 |
| Psmb1 | 6104.0 | -12225.0 |
| Psmb10 | 8202.0 | -4783.0 |
| Psmb11 | 5872.0 | -6129.0 |
| Psmb2 | 7847.0 | -11836.0 |
| Psmb3 | 12063.0 | -13952.0 |
| Psmb4 | -4466.0 | -8497.0 |
| Psmb5 | 10041.0 | -10541.0 |
| Psmb6 | 11789.0 | -12835.0 |
| Psmb7 | 175.0 | -13055.0 |
| Psmb8 | -5795.0 | 2962.0 |
| Psmb9 | -3858.0 | 5687.0 |
| Psmc1 | 11705.0 | -6393.0 |
| Psmc2 | -10211.0 | 7777.0 |
| Psmc3 | 13783.0 | -13466.0 |
| Psmc4 | -7487.0 | 10029.0 |
| Psmc5 | 5939.0 | -5097.0 |
| Psmc6 | -5320.0 | -12074.0 |
| Psmd1 | -4486.0 | -6816.0 |
| Psmd10 | -5266.0 | 7738.0 |
| Psmd11 | -4239.0 | -7981.0 |
| Psmd12 | -5190.0 | -6195.0 |
| Psmd13 | 10924.0 | -7634.0 |
| Psmd14 | -9498.0 | 2769.0 |
| Psmd2 | -11276.0 | 10253.0 |
| Psmd3 | 5369.0 | 146.0 |
| Psmd4 | 8666.0 | -10398.0 |
| Psmd5 | -1595.0 | -6026.0 |
| Psmd6 | -1663.0 | -8390.0 |
| Psmd7 | -9175.0 | -8611.0 |
| Psmd8 | 14709.0 | -14720.0 |
| Psmd9 | 14751.0 | -14675.0 |
| Psme1 | 14335.0 | -14654.0 |
| Psme2b | 158.0 | 1873.0 |
| Psme3 | -3827.0 | 9126.0 |
| Psme4 | -4545.0 | -7955.0 |
| Psmf1 | 3006.0 | 8610.0 |
| Ptpn6 | -8957.0 | 10520.0 |
| Rasgrp1 | -3739.0 | -13175.0 |
| Rasgrp3 | -12035.0 | 12755.0 |
| Rel | 10291.0 | -11414.0 |
| Rela | 7998.0 | -10978.0 |
| Rps27a | 13894.0 | -14715.0 |
| Sh3kbp1 | 6066.0 | -2951.0 |
| Skp1a | -9392.0 | 1413.0 |
| Sos1 | -11977.0 | 9665.0 |
| Stim1 | 14942.0 | -14174.0 |
| Syk | -11535.0 | 11301.0 |
| Trpc1 | -6951.0 | -4789.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Vav1 | -9886.0 | 7973.0 |
Antigen-activates-B-Cell-Receptor-(BCR)-leading-to-generation-of-second-messengers
| metric | value |
|---|---|
| setSize | 42 |
| pMANOVA | 0.00405 |
| p.adjustMANOVA | 0.0186 |
| s.dist | 0.383 |
| s.diab | -0.279 |
| s.PMX | 0.263 |
| p.diab | 0.00174 |
| p.PMX | 0.00322 |
| Gene | diab | PMX |
|---|---|---|
| Ighd | -11252 | 12232 |
| Igkc | -12203 | 11173 |
| Cd79b | -10852 | 12150 |
| Syk | -11535 | 11301 |
| Cd22 | -11312 | 11195 |
| Ighm | -9802 | 12152 |
| Sos1 | -11977 | 9665 |
| Igkv1-135 | -9391 | 12146 |
| Cd79a | -11203 | 8822 |
| Pik3ap1 | -9717 | 10026 |
| Ptpn6 | -8957 | 10520 |
| Vav1 | -9886 | 7973 |
| Pik3cd | -8249 | 9542 |
| Igkv17-127 | -10984 | 6315 |
| Fyn | -6985 | 9856 |
| Btk | -6343 | 9675 |
| Ighv5-4 | -8748 | 6914 |
| Cd19 | -7122 | 7102 |
| Plcg2 | -2480 | 12667 |
| Ighv9-1 | -5234 | 4881 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ahcyl1 | 6832.0 | -14545.0 |
| Blk | 3046.0 | 7612.0 |
| Blnk | 14946.0 | -14514.0 |
| Btk | -6343.0 | 9675.0 |
| Calm1 | 152.0 | -11443.0 |
| Cd19 | -7122.0 | 7102.0 |
| Cd22 | -11312.0 | 11195.0 |
| Cd79a | -11203.0 | 8822.0 |
| Cd79b | -10852.0 | 12150.0 |
| Dapp1 | -3460.0 | -6642.0 |
| Fyn | -6985.0 | 9856.0 |
| Grb2 | 8972.0 | 3406.0 |
| Ighd | -11252.0 | 12232.0 |
| Ighm | -9802.0 | 12152.0 |
| Ighv14-1 | -4909.0 | -6534.0 |
| Ighv3-1 | -3456.5 | 2317.5 |
| Ighv5-4 | -8748.0 | 6914.0 |
| Ighv9-1 | -5234.0 | 4881.0 |
| Igkc | -12203.0 | 11173.0 |
| Igkv1-135 | -9391.0 | 12146.0 |
| Igkv14-130 | -3167.5 | 2317.5 |
| Igkv17-127 | -10984.0 | 6315.0 |
| Igkv2-137 | 6752.0 | -10319.0 |
| Igll1 | 11837.0 | -7314.0 |
| Itpr1 | 10796.0 | -11700.0 |
| Itpr2 | 13551.0 | 7710.0 |
| Itpr3 | 11003.0 | 2102.0 |
| Lyn | -7639.0 | 6.0 |
| Nck1 | -4016.0 | -10473.0 |
| Orai1 | -6072.0 | 1991.0 |
| Orai2 | 10183.0 | -2454.0 |
| Pik3ap1 | -9717.0 | 10026.0 |
| Pik3cd | -8249.0 | 9542.0 |
| Pik3r1 | -5226.0 | 4551.0 |
| Plcg2 | -2480.0 | 12667.0 |
| Ptpn6 | -8957.0 | 10520.0 |
| Sh3kbp1 | 6066.0 | -2951.0 |
| Sos1 | -11977.0 | 9665.0 |
| Stim1 | 14942.0 | -14174.0 |
| Syk | -11535.0 | 11301.0 |
| Trpc1 | -6951.0 | -4789.0 |
| Vav1 | -9886.0 | 7973.0 |
Senescence-Associated-Secretory-Phenotype-(SASP)
| metric | value |
|---|---|
| setSize | 48 |
| pMANOVA | 0.0229 |
| p.adjustMANOVA | 0.096 |
| s.dist | 0.291 |
| s.diab | 0.225 |
| s.PMX | -0.185 |
| p.diab | 0.00693 |
| p.PMX | 0.0265 |
| Gene | diab | PMX |
|---|---|---|
| Cebpb | 15167 | -15133 |
| Stat3 | 14430 | -14454 |
| Cdkn2b | 14383 | -14293 |
| Rps27a | 13894 | -14715 |
| Cdkn1a | 15394 | -12557 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Cdk2 | 12902 | -12285 |
| Ube2d1 | 11721 | -13291 |
| Rps6ka2 | 14482 | -10261 |
| Jun | 9574 | -13518 |
| Rela | 7998 | -10978 |
| Ccna2 | 12043 | -6678 |
| Ube2c | 9861 | -8024 |
| Mapk3 | 10588 | -6813 |
| Mapk1 | 6867 | -10406 |
| Anapc7 | 10824 | -6183 |
| Ube2s | 9693 | -6037 |
| Cdc26 | 8205 | -5823 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278.0 | 10450.0 |
| Anapc10 | -40.0 | -7692.0 |
| Anapc11 | -4767.0 | -2276.0 |
| Anapc15 | -2513.0 | -9553.0 |
| Anapc16 | 13128.0 | -13447.0 |
| Anapc2 | -3217.0 | 9388.0 |
| Anapc4 | 14276.0 | -12248.0 |
| Anapc5 | 14536.0 | -12088.0 |
| Anapc7 | 10824.0 | -6183.0 |
| Ccna2 | 12043.0 | -6678.0 |
| Cdc16 | 10625.0 | -286.0 |
| Cdc23 | 180.0 | 8382.0 |
| Cdc26 | 8205.0 | -5823.0 |
| Cdc27 | -6730.0 | -6274.0 |
| Cdk2 | 12902.0 | -12285.0 |
| Cdk4 | 7497.0 | 6438.0 |
| Cdk6 | -8022.0 | -8784.0 |
| Cdkn1a | 15394.0 | -12557.0 |
| Cdkn1b | 4380.0 | 258.0 |
| Cdkn2b | 14383.0 | -14293.0 |
| Cdkn2c | -1158.0 | 9132.0 |
| Cdkn2d | 5293.0 | 2129.0 |
| Cebpb | 15167.0 | -15133.0 |
| Ehmt1 | -4418.0 | -10516.0 |
| Ehmt2 | 4354.0 | 10437.0 |
| Fos | 5077.0 | 22.0 |
| Fzr1 | -2715.0 | 9851.0 |
| H2afx | -3852.0 | 6424.0 |
| Igfbp7 | -6756.0 | -9670.0 |
| Il1a | 876.5 | -1222.5 |
| Il6 | -2929.0 | 3096.0 |
| Jun | 9574.0 | -13518.0 |
| Mapk1 | 6867.0 | -10406.0 |
| Mapk3 | 10588.0 | -6813.0 |
| Mapk7 | -1452.0 | 6080.0 |
| Nfkb1 | 234.0 | 10216.0 |
| Rela | 7998.0 | -10978.0 |
| Rps27a | 13894.0 | -14715.0 |
| Rps6ka1 | 13571.0 | 8925.0 |
| Rps6ka2 | 14482.0 | -10261.0 |
| Rps6ka3 | -7830.0 | 5782.0 |
| Stat3 | 14430.0 | -14454.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Ube2c | 9861.0 | -8024.0 |
| Ube2d1 | 11721.0 | -13291.0 |
| Ube2e1 | -10811.0 | 7252.0 |
| Ube2s | 9693.0 | -6037.0 |
Cell-surface-interactions-at-the-vascular-wall
| metric | value |
|---|---|
| setSize | 126 |
| pMANOVA | 0.0305 |
| p.adjustMANOVA | 0.117 |
| s.dist | 0.112 |
| s.diab | -0.0184 |
| s.PMX | 0.111 |
| p.diab | 0.722 |
| p.PMX | 0.0314 |
| Gene | diab | PMX |
|---|---|---|
| Itgax | -12597 | 12908 |
| Proc | -12617 | 12555 |
| Jchain | -12711 | 11904 |
| Itgal | -11771 | 12813 |
| Grb7 | -12186 | 12119 |
| Igha | -12348 | 11945 |
| Jam3 | -11372 | 12730 |
| Selplg | -11481 | 12035 |
| Cd44 | -11921 | 11492 |
| Igkc | -12203 | 11173 |
| Itga4 | -10182 | 12732 |
| Sirpa | -10000 | 12631 |
| Atp1b2 | -10533 | 11952 |
| Angpt1 | -10474 | 11969 |
| Sdc2 | -11747 | 10378 |
| Glg1 | -10508 | 11595 |
| Ighm | -9802 | 12152 |
| Sos1 | -11977 | 9665 |
| Igkv1-135 | -9391 | 12146 |
| Pecam1 | -9053 | 12320 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Amica1 | 3041.0 | 6302.0 |
| Angpt1 | -10474.0 | 11969.0 |
| Angpt2 | 10452.0 | -12811.0 |
| Angpt4 | -6900.0 | 10132.0 |
| Apob | 14399.0 | -9778.0 |
| Atp1b1 | 15270.0 | -15047.0 |
| Atp1b2 | -10533.0 | 11952.0 |
| Atp1b3 | 9790.0 | -13383.0 |
| Bsg | 10831.0 | -9772.0 |
| Cav1 | -3675.0 | 10920.0 |
| Cd177 | 3257.0 | 4081.0 |
| Cd2 | -8170.0 | 11027.0 |
| Cd244 | -11574.0 | 9198.0 |
| Cd44 | -11921.0 | 11492.0 |
| Cd47 | -5391.0 | -2458.0 |
| Cd48 | -9932.0 | 9677.0 |
| Cd74 | -8967.0 | 7810.0 |
| Cd84 | -7621.0 | 4187.0 |
| Cd99l2 | -10908.0 | 394.0 |
| Ceacam1 | 10562.0 | 8936.0 |
| Dok2 | 13393.0 | -14065.0 |
| Epcam | 14975.0 | -14340.0 |
| Esam | 13721.0 | -14152.0 |
| F11r | 11089.0 | -13222.0 |
| F2 | -12078.0 | 3049.0 |
| Fcamr | -12383.0 | 8129.0 |
| Fcer1g | -7456.0 | 1655.0 |
| Fn1 | 12346.0 | 6126.0 |
| Fyn | -6985.0 | 9856.0 |
| Gas6 | 13061.0 | 11070.0 |
| Glg1 | -10508.0 | 11595.0 |
| Gm1123 | 9928.0 | -12705.0 |
| Gp6 | -5160.0 | 6084.0 |
| Gpc1 | 15341.0 | -15137.0 |
| Grb14 | 14357.0 | -7399.0 |
| Grb2 | 8972.0 | 3406.0 |
| Grb7 | -12186.0 | 12119.0 |
| Gypa | -10015.0 | 10411.0 |
| Gypc | -1420.0 | 1939.0 |
| Hras | 12615.0 | -11955.0 |
| Igha | -12348.0 | 11945.0 |
| Ighm | -9802.0 | 12152.0 |
| Ighv14-1 | -4909.0 | -6534.0 |
| Ighv3-1 | -3456.5 | 2317.5 |
| Ighv5-4 | -8748.0 | 6914.0 |
| Ighv9-1 | -5234.0 | 4881.0 |
| Igkc | -12203.0 | 11173.0 |
| Igkv1-135 | -9391.0 | 12146.0 |
| Igkv14-130 | -3167.5 | 2317.5 |
| Igkv17-127 | -10984.0 | 6315.0 |
| Igkv2-137 | 6752.0 | -10319.0 |
| Igll1 | 11837.0 | -7314.0 |
| Iglv3 | -6624.0 | 4066.0 |
| Inpp5d | 42.0 | 6163.0 |
| Itga3 | 9099.0 | 6566.0 |
| Itga4 | -10182.0 | 12732.0 |
| Itga5 | -6316.0 | 4295.0 |
| Itga6 | 10749.0 | -2876.0 |
| Itgal | -11771.0 | 12813.0 |
| Itgam | -8058.0 | 4871.0 |
| Itgav | 14776.0 | -14797.0 |
| Itgax | -12597.0 | 12908.0 |
| Itgb1 | 5869.0 | -13098.0 |
| Itgb2l | 4949.0 | -3001.0 |
| Itgb3 | 12310.0 | -13769.0 |
| Jam2 | -8656.0 | -7659.0 |
| Jam3 | -11372.0 | 12730.0 |
| Jchain | -12711.0 | 11904.0 |
| Kras | 8243.0 | -12396.0 |
| L1cam | 15340.0 | -13068.0 |
| Lck | -8490.0 | 10472.0 |
| Lyn | -7639.0 | 6.0 |
| Mag | 6844.0 | -8991.0 |
| Mertk | -7988.0 | -12712.0 |
| Mif | 15323.0 | -14988.0 |
| Nras | 11707.0 | -12390.0 |
| Olr1 | 3032.0 | 2093.0 |
| Pecam1 | -9053.0 | 12320.0 |
| Pf4 | -6840.0 | 3083.0 |
| Pick1 | 8170.0 | -2819.0 |
| Pik3ca | 5274.0 | -12270.0 |
| Pik3cb | -11168.0 | 9586.0 |
| Pik3r1 | -5226.0 | 4551.0 |
| Pik3r2 | -4478.0 | 11254.0 |
| Plcg1 | 15140.0 | -14853.0 |
| Ppia | 14608.0 | -14924.0 |
| Ppil2 | 8843.0 | -12309.0 |
| Proc | -12617.0 | 12555.0 |
| Procr | 6693.0 | 2958.0 |
| Pros1 | 13867.0 | -7111.0 |
| Psg16 | 13818.0 | -14670.0 |
| Ptpn11 | -3808.0 | 6242.0 |
| Ptpn6 | -8957.0 | 10520.0 |
| Sdc1 | 14043.0 | 1649.0 |
| Sdc2 | -11747.0 | 10378.0 |
| Sdc3 | -8537.0 | 11348.0 |
| Sdc4 | -5140.0 | 12375.0 |
| Sele | 11756.0 | -10988.0 |
| Sell | -11269.0 | 9620.0 |
| Selp | 13119.0 | -12994.0 |
| Selplg | -11481.0 | 12035.0 |
| Shc1 | -8826.0 | 9471.0 |
| Sirpa | -10000.0 | 12631.0 |
| Slc16a1 | 14346.0 | -8035.0 |
| Slc16a3 | 11553.0 | -11018.0 |
| Slc16a8 | 11805.0 | -13519.0 |
| Slc3a2 | 12234.0 | -4863.0 |
| Slc7a10 | 7075.0 | -7559.0 |
| Slc7a11 | 11318.0 | -11511.0 |
| Slc7a5 | 14136.0 | -14270.0 |
| Slc7a6 | 12977.0 | -8707.0 |
| Slc7a7 | 9157.0 | 5962.0 |
| Slc7a8 | 13603.0 | 2754.0 |
| Slc7a9 | 10955.0 | -10703.0 |
| Sos1 | -11977.0 | 9665.0 |
| Spn | -3874.0 | 11441.0 |
| Src | 8646.0 | 4243.0 |
| Tek | 3697.0 | 6880.0 |
| Tgfb1 | -11489.0 | 7819.0 |
| Thbd | -2608.0 | 1465.0 |
| Tnfrsf10b | 14466.0 | 8404.0 |
| Trem1 | 6582.0 | 255.0 |
| Tspan7 | 14518.0 | -13734.0 |
| Vpreb1 | 10228.0 | 2737.0 |
| Vpreb3 | -3463.0 | 6270.0 |
| Yes1 | 4717.0 | -6854.0 |
TP53-Regulates-Transcription-of-Genes-Involved-in-G2-Cell-Cycle-Arrest
| metric | value |
|---|---|
| setSize | 18 |
| pMANOVA | 0.0347 |
| p.adjustMANOVA | 0.123 |
| s.dist | 0.331 |
| s.diab | 0.315 |
| s.PMX | -0.1 |
| p.diab | 0.0206 |
| p.PMX | 0.463 |
| Gene | diab | PMX |
|---|---|---|
| Pcna | 13367 | -14114 |
| Tfdp2 | 12095 | -12073 |
| Zfp385a | 15036 | -8764 |
| Cdk1 | 12509 | -9455 |
| Ccnb1 | 14031 | -8068 |
| Aurka | 12135 | -7881 |
| Rbl2 | 11787 | -7420 |
| Cdc25c | 9859 | -6321 |
| Carm1 | 8621 | -6979 |
| Prmt1 | 12405 | -3165 |
| Gadd45a | 2843 | -9278 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Aurka | 12135 | -7881 |
| Bax | 11957 | 8555 |
| Carm1 | 8621 | -6979 |
| Ccnb1 | 14031 | -8068 |
| Cdc25c | 9859 | -6321 |
| Cdk1 | 12509 | -9455 |
| E2f4 | -8258 | 5909 |
| Ep300 | -10091 | 9600 |
| Gadd45a | 2843 | -9278 |
| Pcna | 13367 | -14114 |
| Prmt1 | 12405 | -3165 |
| Rbl1 | -9375 | 11563 |
| Rbl2 | 11787 | -7420 |
| Sfn | 9301 | 71 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Trp53 | -7681 | 5460 |
| Zfp385a | 15036 | -8764 |
TP53-Regulates-Transcription-of-Cell-Cycle-Genes
| metric | value |
|---|---|
| setSize | 46 |
| pMANOVA | 0.0469 |
| p.adjustMANOVA | 0.154 |
| s.dist | 0.217 |
| s.diab | 0.199 |
| s.PMX | -0.0856 |
| p.diab | 0.0195 |
| p.PMX | 0.315 |
| Gene | diab | PMX |
|---|---|---|
| Btg2 | 15122 | -14014 |
| Rgcc | 14711 | -13598 |
| Plk3 | 14013 | -14168 |
| E2f1 | 14773 | -13127 |
| Cdkn1a | 15394 | -12557 |
| Pcna | 13367 | -14114 |
| Cdk2 | 12902 | -12285 |
| Tfdp2 | 12095 | -12073 |
| Zfp385a | 15036 | -8764 |
| Cdk1 | 12509 | -9455 |
| Plagl1 | 14219 | -8257 |
| Ccnb1 | 14031 | -8068 |
| Aurka | 12135 | -7881 |
| Ccne1 | 8507 | -10924 |
| Rbl2 | 11787 | -7420 |
| Ccna2 | 12043 | -6678 |
| Cnot6l | 6231 | -12283 |
| Cdc25c | 9859 | -6321 |
| Carm1 | 8621 | -6979 |
| Tnks1bp1 | 4119 | -14130 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Arid3a | -9238 | 8570 |
| Aurka | 12135 | -7881 |
| Bax | 11957 | 8555 |
| Btg2 | 15122 | -14014 |
| Carm1 | 8621 | -6979 |
| Ccna2 | 12043 | -6678 |
| Ccnb1 | 14031 | -8068 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdc25c | 9859 | -6321 |
| Cdk1 | 12509 | -9455 |
| Cdk2 | 12902 | -12285 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Cenpj | -11728 | 6522 |
| Cnot1 | 2862 | 4781 |
| Cnot10 | 8561 | 1690 |
| Cnot11 | -131 | 2908 |
| Cnot2 | -6965 | 6675 |
| Cnot3 | -8690 | 6241 |
| Cnot4 | -7023 | 1964 |
| Cnot6 | -4378 | 2900 |
| Cnot6l | 6231 | -12283 |
| Cnot7 | -8230 | -5989 |
| Cnot8 | -10527 | 7261 |
| E2f1 | 14773 | -13127 |
| E2f4 | -8258 | 5909 |
| E2f7 | -6064 | 9808 |
| E2f8 | 3208 | 5434 |
| Ep300 | -10091 | 9600 |
| Gadd45a | 2843 | -9278 |
| Pcbp4 | -10989 | 12360 |
| Pcna | 13367 | -14114 |
| Plagl1 | 14219 | -8257 |
| Plk2 | 13531 | 11848 |
| Plk3 | 14013 | -14168 |
| Prmt1 | 12405 | -3165 |
| Rbl1 | -9375 | 11563 |
| Rbl2 | 11787 | -7420 |
| Rgcc | 14711 | -13598 |
| Sfn | 9301 | 71 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Tnks1bp1 | 4119 | -14130 |
| Trp53 | -7681 | 5460 |
| Zfp385a | 15036 | -8764 |
Regulation-of-necroptotic-cell-death
| metric | value |
|---|---|
| setSize | 26 |
| pMANOVA | 0.0572 |
| p.adjustMANOVA | 0.166 |
| s.dist | 0.295 |
| s.diab | 0.133 |
| s.PMX | -0.263 |
| p.diab | 0.242 |
| p.PMX | 0.0202 |
| Gene | diab | PMX |
|---|---|---|
| Sdcbp | 15153 | -15107 |
| Rps27a | 13894 | -14715 |
| Flot1 | 14308 | -13529 |
| Birc3 | 14412 | -13340 |
| Fas | 13656 | -13454 |
| Flot2 | 13212 | -12960 |
| Cflar | 9464 | -13798 |
| Mlkl | 11932 | -10030 |
| Peli1 | 8961 | -12690 |
| Birc2 | 7611 | -10452 |
| Uba52 | 4596 | -6796 |
| Traf2 | 3101 | -8023 |
| Ripk3 | 7523 | -131 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Birc2 | 7611 | -10452 |
| Birc3 | 14412 | -13340 |
| Casp8 | -8679 | -12376 |
| Cdc37 | -1879 | -4421 |
| Cflar | 9464 | -13798 |
| Fadd | -9345 | 10811 |
| Fas | 13656 | -13454 |
| Fasl | -3718 | 6336 |
| Flot1 | 14308 | -13529 |
| Flot2 | 13212 | -12960 |
| Hsp90aa1 | -12505 | 4614 |
| Mlkl | 11932 | -10030 |
| Ogt | -3769 | -9582 |
| Pdcd6ip | -5824 | 3458 |
| Peli1 | 8961 | -12690 |
| Ripk1 | -961 | -5249 |
| Ripk3 | 7523 | -131 |
| Rps27a | 13894 | -14715 |
| Sdcbp | 15153 | -15107 |
| Stub1 | 122 | 4556 |
| Tnfrsf10b | 14466 | 8404 |
| Tnfsf10 | -12009 | 11185 |
| Tradd | -7820 | 11319 |
| Traf2 | 3101 | -8023 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
Apoptotic-cleavage-of-cell-adhesion–proteins
| metric | value |
|---|---|
| setSize | 10 |
| pMANOVA | 0.0609 |
| p.adjustMANOVA | 0.166 |
| s.dist | 0.346 |
| s.diab | 0.343 |
| s.PMX | -0.0441 |
| p.diab | 0.06 |
| p.PMX | 0.809 |
| Gene | diab | PMX |
|---|---|---|
| Dsg2 | 15025 | -13950 |
| Ocln | 13628 | -14190 |
| Dsp | 12069 | -12608 |
| Casp3 | 13749 | -9807 |
| Pkp1 | 11012 | -12124 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Casp3 | 13749 | -9807 |
| Cdh1 | -174 | 12292 |
| Ctnnb1 | -12039 | 12412 |
| Dsg1b | 7980 | 4247 |
| Dsg2 | 15025 | -13950 |
| Dsp | 12069 | -12608 |
| Ocln | 13628 | -14190 |
| Pkp1 | 11012 | -12124 |
| Tjp1 | 7975 | 4697 |
| Tjp2 | -7784 | 12172 |
ERBB2-Regulates-Cell-Motility
| metric | value |
|---|---|
| setSize | 14 |
| pMANOVA | 0.0613 |
| p.adjustMANOVA | 0.166 |
| s.dist | 0.325 |
| s.diab | 0.0805 |
| s.PMX | -0.314 |
| p.diab | 0.602 |
| p.PMX | 0.0416 |
| Gene | diab | PMX |
|---|---|---|
| Diaph1 | 15185.0 | -14589.0 |
| Btc | 14781.0 | -12517.0 |
| Erbb4 | 11714.0 | -13547.0 |
| Erbb3 | 7910.0 | -12688.0 |
| Nrg2 | 6153.0 | -9590.0 |
| Nrg3 | 1803.5 | -1222.5 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Btc | 14781.0 | -12517.0 |
| Diaph1 | 15185.0 | -14589.0 |
| Egf | -9319.0 | 1676.0 |
| Egfr | -4839.0 | 7088.0 |
| Erbb2 | -310.0 | -10575.0 |
| Erbb3 | 7910.0 | -12688.0 |
| Erbb4 | 11714.0 | -13547.0 |
| Ereg | 1803.5 | 699.0 |
| Hbegf | -6264.0 | -7909.0 |
| Memo1 | -6848.0 | -2919.0 |
| Nrg1 | 7244.0 | 7473.0 |
| Nrg2 | 6153.0 | -9590.0 |
| Nrg3 | 1803.5 | -1222.5 |
| Nrg4 | -4847.0 | -8269.0 |
Aberrant-regulation-of-mitotic-cell-cycle-due-to-RB1-defects
| metric | value |
|---|---|
| setSize | 36 |
| pMANOVA | 0.0721 |
| p.adjustMANOVA | 0.182 |
| s.dist | 0.247 |
| s.diab | 0.217 |
| s.PMX | -0.119 |
| p.diab | 0.0242 |
| p.PMX | 0.217 |
| Gene | diab | PMX |
|---|---|---|
| Ccnd3 | 15351 | -15060 |
| Rb1 | 15102 | -13818 |
| E2f1 | 14773 | -13127 |
| Cdkn1a | 15394 | -12557 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Cdk2 | 12902 | -12285 |
| Ube2d1 | 11721 | -13291 |
| Tfdp2 | 12095 | -12073 |
| Ccne1 | 8507 | -10924 |
| Ube2c | 9861 | -8024 |
| Anapc7 | 10824 | -6183 |
| Ube2s | 9693 | -6037 |
| Ccne2 | 4837 | -11061 |
| Cdc26 | 8205 | -5823 |
| Cdc16 | 10625 | -286 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Ccnd1 | 10280 | 12715 |
| Ccnd2 | -10391 | 11271 |
| Ccnd3 | 15351 | -15060 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdc16 | 10625 | -286 |
| Cdc23 | 180 | 8382 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdk2 | 12902 | -12285 |
| Cdk4 | 7497 | 6438 |
| Cdk6 | -8022 | -8784 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Cdkn1c | 11412 | 12041 |
| E2f1 | 14773 | -13127 |
| E2f2 | -10922 | 8773 |
| E2f3 | 9873 | 3869 |
| Fzr1 | -2715 | 9851 |
| Rb1 | 15102 | -13818 |
| Skp2 | -9937 | 5846 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
Diseases-of-mitotic-cell-cycle
| metric | value |
|---|---|
| setSize | 38 |
| pMANOVA | 0.0753 |
| p.adjustMANOVA | 0.182 |
| s.dist | 0.241 |
| s.diab | 0.21 |
| s.PMX | -0.118 |
| p.diab | 0.0249 |
| p.PMX | 0.208 |
| Gene | diab | PMX |
|---|---|---|
| Ccnd3 | 15351 | -15060 |
| Rb1 | 15102 | -13818 |
| E2f1 | 14773 | -13127 |
| Cdkn1a | 15394 | -12557 |
| Anapc16 | 13128 | -13447 |
| Anapc5 | 14536 | -12088 |
| Anapc4 | 14276 | -12248 |
| Cdk2 | 12902 | -12285 |
| Ube2d1 | 11721 | -13291 |
| Tfdp2 | 12095 | -12073 |
| Atrx | 11763 | -12296 |
| Ccne1 | 8507 | -10924 |
| Ube2c | 9861 | -8024 |
| Anapc7 | 10824 | -6183 |
| Ube2s | 9693 | -6037 |
| Ccne2 | 4837 | -11061 |
| Cdc26 | 8205 | -5823 |
| Cdc16 | 10625 | -286 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Anapc1 | -11278 | 10450 |
| Anapc10 | -40 | -7692 |
| Anapc11 | -4767 | -2276 |
| Anapc15 | -2513 | -9553 |
| Anapc16 | 13128 | -13447 |
| Anapc2 | -3217 | 9388 |
| Anapc4 | 14276 | -12248 |
| Anapc5 | 14536 | -12088 |
| Anapc7 | 10824 | -6183 |
| Atrx | 11763 | -12296 |
| Ccnd1 | 10280 | 12715 |
| Ccnd2 | -10391 | 11271 |
| Ccnd3 | 15351 | -15060 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdc16 | 10625 | -286 |
| Cdc23 | 180 | 8382 |
| Cdc26 | 8205 | -5823 |
| Cdc27 | -6730 | -6274 |
| Cdk2 | 12902 | -12285 |
| Cdk4 | 7497 | 6438 |
| Cdk6 | -8022 | -8784 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Cdkn1c | 11412 | 12041 |
| Daxx | -6696 | 7271 |
| E2f1 | 14773 | -13127 |
| E2f2 | -10922 | 8773 |
| E2f3 | 9873 | 3869 |
| Fzr1 | -2715 | 9851 |
| Rb1 | 15102 | -13818 |
| Skp2 | -9937 | 5846 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Ube2c | 9861 | -8024 |
| Ube2d1 | 11721 | -13291 |
| Ube2e1 | -10811 | 7252 |
| Ube2s | 9693 | -6037 |
Nef-mediates-down-modulation-of-cell-surface-receptors-by-recruiting-them-to-clathrin-adapters
| metric | value |
|---|---|
| setSize | 20 |
| pMANOVA | 0.087 |
| p.adjustMANOVA | 0.2 |
| s.dist | 0.189 |
| s.diab | 0.03 |
| s.PMX | 0.186 |
| p.diab | 0.817 |
| p.PMX | 0.149 |
| Gene | diab | PMX |
|---|---|---|
| Ap2a1 | 9324 | 5186 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ap1b1 | 13743 | -84 |
| Ap1g1 | -5711 | 5760 |
| Ap1m1 | -8412 | 11386 |
| Ap1m2 | 14596 | -10523 |
| Ap1s1 | -4270 | 5668 |
| Ap1s2 | 6287 | -8915 |
| Ap1s3 | -6241 | 8053 |
| Ap2a1 | 9324 | 5186 |
| Ap2a2 | -8561 | 11221 |
| Ap2b1 | -9075 | 10334 |
| Ap2m1 | 11298 | -6224 |
| Ap2s1 | 11182 | -5073 |
| Arf1 | -4458 | -3277 |
| Atp6v1h | 9566 | -8530 |
| B2m | 15002 | -15005 |
| Cd28 | -8163 | 8355 |
| Cd4 | -2373 | 10589 |
| Cd8b1 | -4721 | 10118 |
| Lck | -8490 | 10472 |
| Pacs1 | 14041 | -8312 |
Assembly-and-cell-surface-presentation-of-NMDA-receptors
| metric | value |
|---|---|
| setSize | 25 |
| pMANOVA | 0.0983 |
| p.adjustMANOVA | 0.215 |
| s.dist | 0.143 |
| s.diab | 0.122 |
| s.PMX | 0.0746 |
| p.diab | 0.291 |
| p.PMX | 0.518 |
| Gene | diab | PMX |
|---|---|---|
| Nefl | 14459 | 9119 |
| Nbea | 11248 | 7890 |
| Dlg3 | 9912 | 3835 |
| Lin7b | 8739 | 3638 |
| Grin1 | 8164 | 3365 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Actn2 | 13375 | -10971 |
| Apba1 | -6642 | 5916 |
| Camk2a | -8582 | 9297 |
| Camk2b | 12864 | -14402 |
| Camk2d | 14624 | -13868 |
| Camk2g | -9180 | 8979 |
| Cask | 13958 | -14155 |
| Dlg1 | 12024 | -11729 |
| Dlg2 | -8800 | 12793 |
| Dlg3 | 9912 | 3835 |
| Dlg4 | -7223 | 10585 |
| Grin1 | 8164 | 3365 |
| Grin2a | 8133 | -4772 |
| Grin2b | 7538 | -7715 |
| Grin2c | -8070 | 8860 |
| Grin2d | 4321 | -10284 |
| Grin3a | -10410 | 11126 |
| Grin3b | -11710 | 11922 |
| Kif17 | 7565 | -426 |
| Lin7a | -12341 | 7926 |
| Lin7b | 8739 | 3638 |
| Lin7c | -616 | -14468 |
| Lrrc7 | 12248 | -12822 |
| Nbea | 11248 | 7890 |
| Nefl | 14459 | 9119 |
Regulation-of-beta-cell-development
| metric | value |
|---|---|
| setSize | 35 |
| pMANOVA | 0.104 |
| p.adjustMANOVA | 0.217 |
| s.dist | 0.267 |
| s.diab | -0.201 |
| s.PMX | 0.175 |
| p.diab | 0.0391 |
| p.PMX | 0.0725 |
| Gene | diab | PMX |
|---|---|---|
| Hnf1b | -12434 | 12749 |
| Hes1 | -12015 | 11774 |
| Kat2a | -10869 | 12432 |
| Hnf4a | -11415 | 11016 |
| Hnf4g | -12654 | 9829 |
| Akt2 | -10282 | 10289 |
| Nr5a2 | -10147 | 10004 |
| Ep300 | -10091 | 9600 |
| Maml1 | -10807 | 8005 |
| Hnf1a | -10121 | 6985 |
| Notch1 | -8821 | 7415 |
| Foxa3 | -7263 | 7425 |
| Mafa | -5950 | 6802 |
| Gck | -7462 | 1439 |
| Mamld1 | -1846 | 4284 |
| Kat2b | -8046 | 291 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Akt1 | 11899.0 | -4407.0 |
| Akt2 | -10282.0 | 10289.0 |
| Akt3 | -23.0 | -6307.0 |
| Crebbp | 7115.0 | -7498.0 |
| Ep300 | -10091.0 | 9600.0 |
| Fgf10 | -8605.0 | -10192.0 |
| Foxa2 | 2533.5 | 3915.0 |
| Foxa3 | -7263.0 | 7425.0 |
| Foxo1 | 8079.0 | -10792.0 |
| Gck | -7462.0 | 1439.0 |
| Hes1 | -12015.0 | 11774.0 |
| Hnf1a | -10121.0 | 6985.0 |
| Hnf1b | -12434.0 | 12749.0 |
| Hnf4a | -11415.0 | 11016.0 |
| Hnf4g | -12654.0 | 9829.0 |
| Ins2 | 3527.5 | 4487.0 |
| Kat2a | -10869.0 | 12432.0 |
| Kat2b | -8046.0 | 291.0 |
| Mafa | -5950.0 | 6802.0 |
| Maml1 | -10807.0 | 8005.0 |
| Maml2 | 9185.0 | 8307.0 |
| Maml3 | 14706.0 | -12992.0 |
| Mamld1 | -1846.0 | 4284.0 |
| Neurod1 | 876.5 | -1222.5 |
| Nkx2-2 | 2785.0 | -7084.0 |
| Nkx6-1 | 3912.0 | 8261.0 |
| Notch1 | -8821.0 | 7415.0 |
| Nr5a2 | -10147.0 | 10004.0 |
| Onecut3 | 1803.5 | 3123.0 |
| Pax6 | 5690.5 | -5972.0 |
| Pklr | 15118.0 | -15004.0 |
| Ptf1a | 876.5 | -1222.5 |
| Rbpj | -8609.0 | -6259.0 |
| Slc2a2 | 14424.0 | -9637.0 |
| Snw1 | 11427.0 | -10740.0 |
Programmed-Cell-Death
| metric | value |
|---|---|
| setSize | 185 |
| pMANOVA | 0.124 |
| p.adjustMANOVA | 0.247 |
| s.dist | 0.11 |
| s.diab | 0.0683 |
| s.PMX | -0.0861 |
| p.diab | 0.109 |
| p.PMX | 0.0431 |
| Gene | diab | PMX |
|---|---|---|
| Sdcbp | 15153 | -15107 |
| Chmp4c | 14654 | -14956 |
| Psmd8 | 14709 | -14720 |
| Psmd9 | 14751 | -14675 |
| Psme1 | 14335 | -14654 |
| Dsg2 | 15025 | -13950 |
| Stat3 | 14430 | -14454 |
| Sptan1 | 14829 | -14042 |
| Rps27a | 13894 | -14715 |
| E2f1 | 14773 | -13127 |
| Flot1 | 14308 | -13529 |
| Ocln | 13628 | -14190 |
| Psma7 | 13781 | -14022 |
| Birc3 | 14412 | -13340 |
| Bcl2l1 | 13386 | -13994 |
| Psmc3 | 13783 | -13466 |
| Pmaip1 | 15067 | -12274 |
| Fas | 13656 | -13454 |
| Chmp4b | 13369 | -13601 |
| Ppp3cc | 12629 | -13978 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Acin1 | 4961.0 | -6070.0 |
| Add1 | -10711.0 | 8903.0 |
| Akt1 | 11899.0 | -4407.0 |
| Akt2 | -10282.0 | 10289.0 |
| Akt3 | -23.0 | -6307.0 |
| Apaf1 | -3549.0 | 11897.0 |
| Apc | 13349.0 | -8999.0 |
| Apip | 10598.0 | -8306.0 |
| Appl1 | 8488.0 | -13267.0 |
| Arhgap10 | -12730.0 | 13015.0 |
| Aven | -9158.0 | 11505.0 |
| Bad | -4775.0 | 1095.0 |
| Bak1 | 14669.0 | -8609.0 |
| Bax | 11957.0 | 8555.0 |
| Bcap31 | -10749.0 | -2252.0 |
| Bcl2 | -6750.0 | 11042.0 |
| Bcl2l1 | 13386.0 | -13994.0 |
| Bcl2l11 | 10641.0 | -10810.0 |
| Bid | -5300.0 | 6403.0 |
| Birc2 | 7611.0 | -10452.0 |
| Birc3 | 14412.0 | -13340.0 |
| Bmf | -9386.0 | 7691.0 |
| Bmx | -2611.0 | 8210.0 |
| C1qbp | -5400.0 | 10357.0 |
| Casp1 | -11186.0 | 11334.0 |
| Casp3 | 13749.0 | -9807.0 |
| Casp4 | -6856.0 | -8055.0 |
| Casp6 | -1176.0 | 5396.0 |
| Casp7 | 11312.0 | 4968.0 |
| Casp8 | -8679.0 | -12376.0 |
| Casp9 | -10349.0 | 10594.0 |
| Cd14 | 11247.0 | -14430.0 |
| Cdc37 | -1879.0 | -4421.0 |
| Cdh1 | -174.0 | 12292.0 |
| Cflar | 9464.0 | -13798.0 |
| Chmp2a | 6531.0 | -8482.0 |
| Chmp2b | 11049.0 | -9912.0 |
| Chmp3 | 8777.0 | -13102.0 |
| Chmp4b | 13369.0 | -13601.0 |
| Chmp4c | 14654.0 | -14956.0 |
| Chmp6 | 9126.0 | 9611.0 |
| Chmp7 | -7612.0 | 12648.0 |
| Clspn | -4322.0 | 6551.0 |
| Ctnnb1 | -12039.0 | 12412.0 |
| Cycs | 8402.0 | -13138.0 |
| Dapk1 | -3551.0 | 5160.0 |
| Dapk2 | -5181.0 | 12350.0 |
| Dapk3 | -221.0 | -3347.0 |
| Dbnl | 9368.0 | 7787.0 |
| Dffa | -1172.0 | 12098.0 |
| Dffb | 11853.0 | -11341.0 |
| Diablo | -5963.0 | 8829.0 |
| Dnm1l | 8840.0 | -11982.0 |
| Dsg1b | 7980.0 | 4247.0 |
| Dsg2 | 15025.0 | -13950.0 |
| Dsp | 12069.0 | -12608.0 |
| Dynll1 | -10023.0 | -2241.0 |
| Dynll2 | -12351.0 | 10871.0 |
| E2f1 | 14773.0 | -13127.0 |
| Fadd | -9345.0 | 10811.0 |
| Fas | 13656.0 | -13454.0 |
| Fasl | -3718.0 | 6336.0 |
| Flot1 | 14308.0 | -13529.0 |
| Flot2 | 13212.0 | -12960.0 |
| Fnta | 12029.0 | -12661.0 |
| Gas2 | -12652.0 | 10306.0 |
| Gsdmd | -5959.0 | 7991.0 |
| Gsn | 14953.0 | -5680.0 |
| Hmgb2 | -1509.0 | 5671.0 |
| Hsp90aa1 | -12505.0 | 4614.0 |
| Il18 | 9046.0 | 6574.0 |
| Il1a | 876.5 | -1222.5 |
| Il1b | -10853.0 | 6461.0 |
| Irf1 | -9511.0 | 10928.0 |
| Irf2 | -4303.0 | -418.0 |
| Kpna1 | 7639.0 | -11114.0 |
| Kpnb1 | 10908.0 | 1199.0 |
| Lmna | 5606.0 | 3857.0 |
| Lmnb1 | -9916.0 | 8126.0 |
| Ly96 | 201.0 | -8287.0 |
| Maged1 | -11852.0 | 11971.0 |
| Mapk1 | 6867.0 | -10406.0 |
| Mapk3 | 10588.0 | -6813.0 |
| Mapk8 | 86.0 | 2880.0 |
| Mapt | -11830.0 | 11877.0 |
| Mlkl | 11932.0 | -10030.0 |
| Nmt1 | -8697.0 | 6173.0 |
| Ocln | 13628.0 | -14190.0 |
| Ogt | -3769.0 | -9582.0 |
| Oma1 | -3059.0 | 5581.0 |
| Opa1 | 343.0 | -428.0 |
| Pak2 | -11115.0 | 10419.0 |
| Pdcd6ip | -5824.0 | 3458.0 |
| Peli1 | 8961.0 | -12690.0 |
| Pkp1 | 11012.0 | -12124.0 |
| Plec | 11898.0 | -8539.0 |
| Pmaip1 | 15067.0 | -12274.0 |
| Ppp1r13b | 12643.0 | 273.0 |
| Ppp3cc | 12629.0 | -13978.0 |
| Ppp3r1 | 8691.0 | -9297.0 |
| Prkcd | 11350.0 | -8872.0 |
| Prkcq | -6737.0 | 3402.0 |
| Psma1 | -6738.0 | -7608.0 |
| Psma2 | 2844.0 | -13370.0 |
| Psma3 | 9490.0 | -12548.0 |
| Psma4 | 4617.0 | -12505.0 |
| Psma5 | 5504.0 | -11202.0 |
| Psma6 | 9985.0 | -12478.0 |
| Psma7 | 13781.0 | -14022.0 |
| Psma8 | -7575.0 | 7041.0 |
| Psmb1 | 6104.0 | -12225.0 |
| Psmb10 | 8202.0 | -4783.0 |
| Psmb11 | 5872.0 | -6129.0 |
| Psmb2 | 7847.0 | -11836.0 |
| Psmb3 | 12063.0 | -13952.0 |
| Psmb4 | -4466.0 | -8497.0 |
| Psmb5 | 10041.0 | -10541.0 |
| Psmb6 | 11789.0 | -12835.0 |
| Psmb7 | 175.0 | -13055.0 |
| Psmb8 | -5795.0 | 2962.0 |
| Psmb9 | -3858.0 | 5687.0 |
| Psmc1 | 11705.0 | -6393.0 |
| Psmc2 | -10211.0 | 7777.0 |
| Psmc3 | 13783.0 | -13466.0 |
| Psmc4 | -7487.0 | 10029.0 |
| Psmc5 | 5939.0 | -5097.0 |
| Psmc6 | -5320.0 | -12074.0 |
| Psmd1 | -4486.0 | -6816.0 |
| Psmd10 | -5266.0 | 7738.0 |
| Psmd11 | -4239.0 | -7981.0 |
| Psmd12 | -5190.0 | -6195.0 |
| Psmd13 | 10924.0 | -7634.0 |
| Psmd14 | -9498.0 | 2769.0 |
| Psmd2 | -11276.0 | 10253.0 |
| Psmd3 | 5369.0 | 146.0 |
| Psmd4 | 8666.0 | -10398.0 |
| Psmd5 | -1595.0 | -6026.0 |
| Psmd6 | -1663.0 | -8390.0 |
| Psmd7 | -9175.0 | -8611.0 |
| Psmd8 | 14709.0 | -14720.0 |
| Psmd9 | 14751.0 | -14675.0 |
| Psme1 | 14335.0 | -14654.0 |
| Psme2b | 158.0 | 1873.0 |
| Psme3 | -3827.0 | 9126.0 |
| Psme4 | -4545.0 | -7955.0 |
| Psmf1 | 3006.0 | 8610.0 |
| Ptk2 | 9305.0 | 2859.0 |
| Ripk1 | -961.0 | -5249.0 |
| Ripk3 | 7523.0 | -131.0 |
| Rock1 | 4877.0 | -11833.0 |
| Rps27a | 13894.0 | -14715.0 |
| Satb1 | -8419.0 | 10588.0 |
| Sdcbp | 15153.0 | -15107.0 |
| Sfn | 9301.0 | 71.0 |
| Sptan1 | 14829.0 | -14042.0 |
| Stat3 | 14430.0 | -14454.0 |
| Stk24 | 12867.0 | -7841.0 |
| Stk26 | 13103.0 | -8575.0 |
| Stub1 | 122.0 | 4556.0 |
| Tfdp1 | -7152.0 | 7854.0 |
| Tfdp2 | 12095.0 | -12073.0 |
| Ticam1 | -7259.0 | 6702.0 |
| Ticam2 | 4701.0 | -9812.0 |
| Tjp1 | 7975.0 | 4697.0 |
| Tjp2 | -7784.0 | 12172.0 |
| Tlr4 | -8099.0 | 6708.0 |
| Tnfrsf10b | 14466.0 | 8404.0 |
| Tnfsf10 | -12009.0 | 11185.0 |
| Tradd | -7820.0 | 11319.0 |
| Traf2 | 3101.0 | -8023.0 |
| Trp53 | -7681.0 | 5460.0 |
| Trp53bp2 | 12692.0 | -12481.0 |
| Trp63 | -5205.0 | -10040.0 |
| Trp73 | 5178.0 | 5617.0 |
| Uaca | -9406.0 | 12139.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Unc5a | -8229.0 | 9426.0 |
| Unc5b | 14534.0 | 9226.0 |
| Vim | -6719.0 | 11410.0 |
| Ywhab | -3531.0 | -52.0 |
| Ywhae | 2275.0 | -8018.0 |
| Ywhag | -10205.0 | 10203.0 |
| Ywhah | 3055.0 | -11126.0 |
| Ywhaq | 12431.0 | -12558.0 |
Sema4D-induced-cell-migration-and-growth-cone-collapse
| metric | value |
|---|---|
| setSize | 19 |
| pMANOVA | 0.152 |
| p.adjustMANOVA | 0.292 |
| s.dist | 0.214 |
| s.diab | 0.211 |
| s.PMX | -0.0374 |
| p.diab | 0.111 |
| p.PMX | 0.778 |
| Gene | diab | PMX |
|---|---|---|
| Myl6 | 11221 | -14108 |
| Limk2 | 14475 | -9474 |
| Myl12b | 10115 | -13120 |
| Rhob | 9640 | -12113 |
| Rock2 | 7938 | -13372 |
| Myh14 | 10015 | -8495 |
| Rock1 | 4877 | -11833 |
| Plxnb1 | 11092 | -4388 |
| Myl9 | 9432 | -4957 |
| Arhgef11 | 9956 | -369 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Arhgef11 | 9956 | -369 |
| Arhgef12 | -12030 | 10200 |
| Erbb2 | -310 | -10575 |
| Limk1 | 11390 | 3370 |
| Limk2 | 14475 | -9474 |
| Myh10 | 9979 | 12027 |
| Myh11 | 10080 | 12361 |
| Myh14 | 10015 | -8495 |
| Myh9 | -3199 | 2907 |
| Myl12b | 10115 | -13120 |
| Myl6 | 11221 | -14108 |
| Myl9 | 9432 | -4957 |
| Plxnb1 | 11092 | -4388 |
| Rhob | 9640 | -12113 |
| Rhoc | -10110 | 8403 |
| Rnd1 | -10960 | 10295 |
| Rock1 | 4877 | -11833 |
| Rock2 | 7938 | -13372 |
| Sema4d | -12323 | 13004 |
Cell-Cell-communication
| metric | value |
|---|---|
| setSize | 110 |
| pMANOVA | 0.202 |
| p.adjustMANOVA | 0.361 |
| s.dist | 0.0863 |
| s.diab | 0.084 |
| s.PMX | -0.0197 |
| p.diab | 0.128 |
| p.PMX | 0.721 |
| Gene | diab | PMX |
|---|---|---|
| Nectin1 | 15040 | -14466 |
| Sptbn1 | 14290 | -14606 |
| Sptan1 | 14829 | -14042 |
| Cdh6 | 14279 | -14377 |
| Cldn19 | 14026 | -14397 |
| Cask | 13958 | -14155 |
| Cldn3 | 13399 | -14457 |
| Lamc2 | 15047 | -12749 |
| Parva | 14174 | -13205 |
| Itgb4 | 14708 | -12358 |
| Nectin2 | 14700 | -12326 |
| Lamb3 | 12930 | -13656 |
| Cldn4 | 14680 | -11852 |
| Cldn15 | 14862 | -11517 |
| Cd151 | 12960 | -12761 |
| Cd2ap | 13647 | -11788 |
| Col17a1 | 13341 | -11901 |
| Dst | 12167 | -12864 |
| Cdh4 | 12570 | -12281 |
| Iqgap1 | 14527 | -10145 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Actn1 | -2955.0 | -9395.0 |
| Actn2 | 13375.0 | -10971.0 |
| Actn3 | 11524.0 | 2632.0 |
| Actn4 | 5239.0 | 9097.0 |
| Arhgef6 | 10050.0 | 5932.0 |
| Cadm1 | -12680.0 | 12287.0 |
| Cadm2 | -7082.0 | 12271.0 |
| Cadm3 | 4497.0 | 5204.0 |
| Cask | 13958.0 | -14155.0 |
| Cd151 | 12960.0 | -12761.0 |
| Cd2ap | 13647.0 | -11788.0 |
| Cd47 | -5391.0 | -2458.0 |
| Cdh1 | -174.0 | 12292.0 |
| Cdh10 | -3437.0 | 7052.5 |
| Cdh11 | -9468.0 | 12564.0 |
| Cdh13 | -11949.0 | 12201.0 |
| Cdh17 | 4740.0 | -8372.0 |
| Cdh2 | -12474.0 | 5089.0 |
| Cdh24 | -3952.0 | 8158.0 |
| Cdh3 | 14386.0 | -9982.0 |
| Cdh4 | 12570.0 | -12281.0 |
| Cdh5 | -9073.0 | 12582.0 |
| Cdh6 | 14279.0 | -14377.0 |
| Cdh8 | 1803.5 | -2073.5 |
| Cldn1 | 12954.0 | 2518.0 |
| Cldn10 | -12555.0 | 9350.0 |
| Cldn11 | 11784.0 | -9936.0 |
| Cldn12 | -10344.0 | -6381.0 |
| Cldn14 | 13725.0 | -8003.0 |
| Cldn15 | 14862.0 | -11517.0 |
| Cldn16 | -7272.0 | 7202.0 |
| Cldn17 | -5763.0 | 1333.0 |
| Cldn18 | -11451.0 | 9869.0 |
| Cldn19 | 14026.0 | -14397.0 |
| Cldn2 | 7747.0 | -14483.0 |
| Cldn20 | -119.0 | -6513.0 |
| Cldn23 | 10399.0 | -12378.0 |
| Cldn3 | 13399.0 | -14457.0 |
| Cldn4 | 14680.0 | -11852.0 |
| Cldn5 | -4673.0 | 11618.0 |
| Cldn6 | -8284.0 | 5503.0 |
| Cldn7 | 13810.0 | -9723.0 |
| Cldn8 | 13832.0 | 3064.0 |
| Cldn9 | -6452.0 | -4993.0 |
| Col17a1 | 13341.0 | -11901.0 |
| Crb3 | 11061.0 | 5579.0 |
| Ctnna1 | 5895.0 | 2751.0 |
| Ctnnb1 | -12039.0 | 12412.0 |
| Dst | 12167.0 | -12864.0 |
| F11r | 11089.0 | -13222.0 |
| Fblim1 | -2605.0 | -9339.0 |
| Fermt2 | -6317.0 | -9249.0 |
| Flna | -8364.0 | 9099.0 |
| Flnc | 5925.0 | -12857.0 |
| Fyb | -11760.0 | 9306.0 |
| Fyn | -6985.0 | 9856.0 |
| Grb2 | 8972.0 | 3406.0 |
| Ilk | -313.0 | -495.0 |
| Iqgap1 | 14527.0 | -10145.0 |
| Itga6 | 10749.0 | -2876.0 |
| Itgb1 | 5869.0 | -13098.0 |
| Itgb4 | 14708.0 | -12358.0 |
| Jup | -4725.0 | 9124.0 |
| Kirrel | -5626.0 | 10328.0 |
| Kirrel2 | 8017.0 | 6175.0 |
| Kirrel3 | -9431.0 | 2836.0 |
| Lama3 | -9254.0 | 7235.0 |
| Lamb3 | 12930.0 | -13656.0 |
| Lamc2 | 15047.0 | -12749.0 |
| Lims1 | -8618.0 | 3597.0 |
| Lims2 | -11479.0 | 10148.0 |
| Magi2 | -8986.0 | 11098.0 |
| Mpp5 | -10314.0 | -13200.0 |
| Nck1 | -4016.0 | -10473.0 |
| Nck2 | -5920.0 | 1627.0 |
| Nectin1 | 15040.0 | -14466.0 |
| Nectin2 | 14700.0 | -12326.0 |
| Nectin3 | -11266.0 | 9186.0 |
| Nectin4 | 10771.0 | 7852.0 |
| Nphs1 | 9978.0 | 11962.0 |
| Pard3 | -7793.0 | -5508.0 |
| Pard6a | 2407.0 | -8357.0 |
| Pard6b | -34.0 | 10283.0 |
| Pard6g | 11905.0 | 6083.0 |
| Parva | 14174.0 | -13205.0 |
| Parvb | -6686.0 | -4411.0 |
| Pik3ca | 5274.0 | -12270.0 |
| Pik3cb | -11168.0 | 9586.0 |
| Pik3r1 | -5226.0 | 4551.0 |
| Pik3r2 | -4478.0 | 11254.0 |
| Plec | 11898.0 | -8539.0 |
| Prkci | 7391.0 | -10491.0 |
| Ptk2 | 9305.0 | 2859.0 |
| Ptk2b | -11310.0 | 12917.0 |
| Ptpn11 | -3808.0 | 6242.0 |
| Ptpn6 | -8957.0 | 10520.0 |
| Pvr | 12149.0 | -11086.0 |
| Pxn | 5824.0 | -177.0 |
| Rsu1 | -7576.0 | -2947.0 |
| Sdk1 | 14935.0 | -6001.0 |
| Sdk2 | 14079.0 | -7766.0 |
| Sirpa | -10000.0 | 12631.0 |
| Skap2 | 5625.0 | -6565.0 |
| Sptan1 | 14829.0 | -14042.0 |
| Sptbn1 | 14290.0 | -14606.0 |
| Src | 8646.0 | 4243.0 |
| Tesk1 | 7984.0 | 9088.0 |
| Tyrobp | -4198.0 | -8348.0 |
| Vasp | -3832.0 | 4449.0 |
| Wasl | 6310.0 | -10820.0 |
Cell-extracellular-matrix-interactions
| metric | value |
|---|---|
| setSize | 16 |
| pMANOVA | 0.204 |
| p.adjustMANOVA | 0.361 |
| s.dist | 0.15 |
| s.diab | -0.132 |
| s.PMX | -0.0703 |
| p.diab | 0.359 |
| p.PMX | 0.627 |
| Gene | diab | PMX |
|---|---|---|
| Fermt2 | -6317 | -9249 |
| Parvb | -6686 | -4411 |
| Actn1 | -2955 | -9395 |
| Fblim1 | -2605 | -9339 |
| Rsu1 | -7576 | -2947 |
| Ilk | -313 | -495 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Actn1 | -2955 | -9395 |
| Arhgef6 | 10050 | 5932 |
| Fblim1 | -2605 | -9339 |
| Fermt2 | -6317 | -9249 |
| Flna | -8364 | 9099 |
| Flnc | 5925 | -12857 |
| Ilk | -313 | -495 |
| Itgb1 | 5869 | -13098 |
| Lims1 | -8618 | 3597 |
| Lims2 | -11479 | 10148 |
| Parva | 14174 | -13205 |
| Parvb | -6686 | -4411 |
| Pxn | 5824 | -177 |
| Rsu1 | -7576 | -2947 |
| Tesk1 | 7984 | 9088 |
| Vasp | -3832 | 4449 |
Cell-junction-organization
| metric | value |
|---|---|
| setSize | 78 |
| pMANOVA | 0.217 |
| p.adjustMANOVA | 0.369 |
| s.dist | 0.141 |
| s.diab | 0.114 |
| s.PMX | -0.083 |
| p.diab | 0.0808 |
| p.PMX | 0.205 |
| Gene | diab | PMX |
|---|---|---|
| Nectin1 | 15040 | -14466 |
| Cdh6 | 14279 | -14377 |
| Cldn19 | 14026 | -14397 |
| Cldn3 | 13399 | -14457 |
| Lamc2 | 15047 | -12749 |
| Parva | 14174 | -13205 |
| Itgb4 | 14708 | -12358 |
| Nectin2 | 14700 | -12326 |
| Lamb3 | 12930 | -13656 |
| Cldn4 | 14680 | -11852 |
| Cldn15 | 14862 | -11517 |
| Cd151 | 12960 | -12761 |
| Col17a1 | 13341 | -11901 |
| Dst | 12167 | -12864 |
| Cdh4 | 12570 | -12281 |
| F11r | 11089 | -13222 |
| Cdh3 | 14386 | -9982 |
| Pvr | 12149 | -11086 |
| Cldn7 | 13810 | -9723 |
| Cldn23 | 10399 | -12378 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Actn1 | -2955.0 | -9395.0 |
| Arhgef6 | 10050.0 | 5932.0 |
| Cadm1 | -12680.0 | 12287.0 |
| Cadm2 | -7082.0 | 12271.0 |
| Cadm3 | 4497.0 | 5204.0 |
| Cd151 | 12960.0 | -12761.0 |
| Cdh1 | -174.0 | 12292.0 |
| Cdh10 | -3437.0 | 7052.5 |
| Cdh11 | -9468.0 | 12564.0 |
| Cdh13 | -11949.0 | 12201.0 |
| Cdh17 | 4740.0 | -8372.0 |
| Cdh2 | -12474.0 | 5089.0 |
| Cdh24 | -3952.0 | 8158.0 |
| Cdh3 | 14386.0 | -9982.0 |
| Cdh4 | 12570.0 | -12281.0 |
| Cdh5 | -9073.0 | 12582.0 |
| Cdh6 | 14279.0 | -14377.0 |
| Cdh8 | 1803.5 | -2073.5 |
| Cldn1 | 12954.0 | 2518.0 |
| Cldn10 | -12555.0 | 9350.0 |
| Cldn11 | 11784.0 | -9936.0 |
| Cldn12 | -10344.0 | -6381.0 |
| Cldn14 | 13725.0 | -8003.0 |
| Cldn15 | 14862.0 | -11517.0 |
| Cldn16 | -7272.0 | 7202.0 |
| Cldn17 | -5763.0 | 1333.0 |
| Cldn18 | -11451.0 | 9869.0 |
| Cldn19 | 14026.0 | -14397.0 |
| Cldn2 | 7747.0 | -14483.0 |
| Cldn20 | -119.0 | -6513.0 |
| Cldn23 | 10399.0 | -12378.0 |
| Cldn3 | 13399.0 | -14457.0 |
| Cldn4 | 14680.0 | -11852.0 |
| Cldn5 | -4673.0 | 11618.0 |
| Cldn6 | -8284.0 | 5503.0 |
| Cldn7 | 13810.0 | -9723.0 |
| Cldn8 | 13832.0 | 3064.0 |
| Cldn9 | -6452.0 | -4993.0 |
| Col17a1 | 13341.0 | -11901.0 |
| Crb3 | 11061.0 | 5579.0 |
| Ctnna1 | 5895.0 | 2751.0 |
| Ctnnb1 | -12039.0 | 12412.0 |
| Dst | 12167.0 | -12864.0 |
| F11r | 11089.0 | -13222.0 |
| Fblim1 | -2605.0 | -9339.0 |
| Fermt2 | -6317.0 | -9249.0 |
| Flna | -8364.0 | 9099.0 |
| Flnc | 5925.0 | -12857.0 |
| Ilk | -313.0 | -495.0 |
| Itga6 | 10749.0 | -2876.0 |
| Itgb1 | 5869.0 | -13098.0 |
| Itgb4 | 14708.0 | -12358.0 |
| Jup | -4725.0 | 9124.0 |
| Lama3 | -9254.0 | 7235.0 |
| Lamb3 | 12930.0 | -13656.0 |
| Lamc2 | 15047.0 | -12749.0 |
| Lims1 | -8618.0 | 3597.0 |
| Lims2 | -11479.0 | 10148.0 |
| Mpp5 | -10314.0 | -13200.0 |
| Nectin1 | 15040.0 | -14466.0 |
| Nectin2 | 14700.0 | -12326.0 |
| Nectin3 | -11266.0 | 9186.0 |
| Nectin4 | 10771.0 | 7852.0 |
| Pard3 | -7793.0 | -5508.0 |
| Pard6a | 2407.0 | -8357.0 |
| Pard6b | -34.0 | 10283.0 |
| Pard6g | 11905.0 | 6083.0 |
| Parva | 14174.0 | -13205.0 |
| Parvb | -6686.0 | -4411.0 |
| Plec | 11898.0 | -8539.0 |
| Prkci | 7391.0 | -10491.0 |
| Pvr | 12149.0 | -11086.0 |
| Pxn | 5824.0 | -177.0 |
| Rsu1 | -7576.0 | -2947.0 |
| Sdk1 | 14935.0 | -6001.0 |
| Sdk2 | 14079.0 | -7766.0 |
| Tesk1 | 7984.0 | 9088.0 |
| Vasp | -3832.0 | 4449.0 |
MET-promotes-cell-motility
| metric | value |
|---|---|
| setSize | 29 |
| pMANOVA | 0.23 |
| p.adjustMANOVA | 0.378 |
| s.dist | 0.186 |
| s.diab | -0.0701 |
| s.PMX | 0.172 |
| p.diab | 0.513 |
| p.PMX | 0.109 |
| Gene | diab | PMX |
|---|---|---|
| Met | -12780 | 12742 |
| Lama4 | -12738 | 12562 |
| Tns3 | -12632 | 12630 |
| Lama2 | -12274 | 12567 |
| Lamc3 | -12142 | 12570 |
| Crkl | -11519 | 10889 |
| Hgf | -12068 | 9941 |
| Lamb1 | -8857 | 11401 |
| Lama1 | -6518 | 12437 |
| Lama3 | -9254 | 7235 |
| Rac1 | -4047 | 262 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Crk | -5870 | -9136 |
| Crkl | -11519 | 10889 |
| Dock7 | 14759 | -14157 |
| Gab1 | -9889 | -8445 |
| Grb2 | 8972 | 3406 |
| Hgf | -12068 | 9941 |
| Itga2 | 7236 | -6041 |
| Itga3 | 9099 | 6566 |
| Itgb1 | 5869 | -13098 |
| Lama1 | -6518 | 12437 |
| Lama2 | -12274 | 12567 |
| Lama3 | -9254 | 7235 |
| Lama4 | -12738 | 12562 |
| Lama5 | 14788 | -8076 |
| Lamb1 | -8857 | 11401 |
| Lamb2 | 7606 | 8928 |
| Lamb3 | 12930 | -13656 |
| Lamc1 | 13297 | -9372 |
| Lamc2 | 15047 | -12749 |
| Lamc3 | -12142 | 12570 |
| Met | -12780 | 12742 |
| Ptk2 | 9305 | 2859 |
| Rac1 | -4047 | 262 |
| Rap1a | -234 | -12456 |
| Rap1b | -1828 | -11439 |
| Rapgef1 | 6711 | 11910 |
| Src | 8646 | 4243 |
| Tns3 | -12632 | 12630 |
| Tns4 | 7660 | 4798 |
FOXO-mediated-transcription-of-cell-cycle-genes
| metric | value |
|---|---|
| setSize | 15 |
| pMANOVA | 0.262 |
| p.adjustMANOVA | 0.416 |
| s.dist | 0.314 |
| s.diab | 0.236 |
| s.PMX | -0.207 |
| p.diab | 0.114 |
| p.PMX | 0.165 |
| Gene | diab | PMX |
|---|---|---|
| Btg1 | 15032 | -15019 |
| Foxo3 | 14625 | -14429 |
| Klf4 | 13879 | -14736 |
| Ccng2 | 13968 | -14417 |
| Cdkn1a | 15394 | -12557 |
| Rbl2 | 11787 | -7420 |
| Foxo1 | 8079 | -10792 |
| Smad4 | 10397 | -4745 |
| Gadd45a | 2843 | -9278 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Btg1 | 15032 | -15019 |
| Cav1 | -3675 | 10920 |
| Ccng2 | 13968 | -14417 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Foxo1 | 8079 | -10792 |
| Foxo3 | 14625 | -14429 |
| Foxo4 | -4785 | 2785 |
| Gadd45a | 2843 | -9278 |
| Klf4 | 13879 | -14736 |
| Pcbp4 | -10989 | 12360 |
| Rbl2 | 11787 | -7420 |
| Smad2 | -9935 | 4570 |
| Smad3 | -11617 | 12814 |
| Smad4 | 10397 | -4745 |
Cell-cell-junction-organization
| metric | value |
|---|---|
| setSize | 53 |
| pMANOVA | 0.274 |
| p.adjustMANOVA | 0.416 |
| s.dist | 0.0972 |
| s.diab | 0.097 |
| s.PMX | -0.00576 |
| p.diab | 0.222 |
| p.PMX | 0.942 |
| Gene | diab | PMX |
|---|---|---|
| Nectin1 | 15040 | -14466 |
| Cdh6 | 14279 | -14377 |
| Cldn19 | 14026 | -14397 |
| Cldn3 | 13399 | -14457 |
| Nectin2 | 14700 | -12326 |
| Cldn4 | 14680 | -11852 |
| Cldn15 | 14862 | -11517 |
| Cdh4 | 12570 | -12281 |
| F11r | 11089 | -13222 |
| Cdh3 | 14386 | -9982 |
| Pvr | 12149 | -11086 |
| Cldn7 | 13810 | -9723 |
| Cldn23 | 10399 | -12378 |
| Cldn11 | 11784 | -9936 |
| Cldn2 | 7747 | -14483 |
| Cldn14 | 13725 | -8003 |
| Sdk2 | 14079 | -7766 |
| Sdk1 | 14935 | -6001 |
| Prkci | 7391 | -10491 |
| Cdh17 | 4740 | -8372 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Cadm1 | -12680.0 | 12287.0 |
| Cadm2 | -7082.0 | 12271.0 |
| Cadm3 | 4497.0 | 5204.0 |
| Cdh1 | -174.0 | 12292.0 |
| Cdh10 | -3437.0 | 7052.5 |
| Cdh11 | -9468.0 | 12564.0 |
| Cdh13 | -11949.0 | 12201.0 |
| Cdh17 | 4740.0 | -8372.0 |
| Cdh2 | -12474.0 | 5089.0 |
| Cdh24 | -3952.0 | 8158.0 |
| Cdh3 | 14386.0 | -9982.0 |
| Cdh4 | 12570.0 | -12281.0 |
| Cdh5 | -9073.0 | 12582.0 |
| Cdh6 | 14279.0 | -14377.0 |
| Cdh8 | 1803.5 | -2073.5 |
| Cldn1 | 12954.0 | 2518.0 |
| Cldn10 | -12555.0 | 9350.0 |
| Cldn11 | 11784.0 | -9936.0 |
| Cldn12 | -10344.0 | -6381.0 |
| Cldn14 | 13725.0 | -8003.0 |
| Cldn15 | 14862.0 | -11517.0 |
| Cldn16 | -7272.0 | 7202.0 |
| Cldn17 | -5763.0 | 1333.0 |
| Cldn18 | -11451.0 | 9869.0 |
| Cldn19 | 14026.0 | -14397.0 |
| Cldn2 | 7747.0 | -14483.0 |
| Cldn20 | -119.0 | -6513.0 |
| Cldn23 | 10399.0 | -12378.0 |
| Cldn3 | 13399.0 | -14457.0 |
| Cldn4 | 14680.0 | -11852.0 |
| Cldn5 | -4673.0 | 11618.0 |
| Cldn6 | -8284.0 | 5503.0 |
| Cldn7 | 13810.0 | -9723.0 |
| Cldn8 | 13832.0 | 3064.0 |
| Cldn9 | -6452.0 | -4993.0 |
| Crb3 | 11061.0 | 5579.0 |
| Ctnna1 | 5895.0 | 2751.0 |
| Ctnnb1 | -12039.0 | 12412.0 |
| F11r | 11089.0 | -13222.0 |
| Jup | -4725.0 | 9124.0 |
| Mpp5 | -10314.0 | -13200.0 |
| Nectin1 | 15040.0 | -14466.0 |
| Nectin2 | 14700.0 | -12326.0 |
| Nectin3 | -11266.0 | 9186.0 |
| Nectin4 | 10771.0 | 7852.0 |
| Pard3 | -7793.0 | -5508.0 |
| Pard6a | 2407.0 | -8357.0 |
| Pard6b | -34.0 | 10283.0 |
| Pard6g | 11905.0 | 6083.0 |
| Prkci | 7391.0 | -10491.0 |
| Pvr | 12149.0 | -11086.0 |
| Sdk1 | 14935.0 | -6001.0 |
| Sdk2 | 14079.0 | -7766.0 |
VEGFR2-mediated-cell-proliferation
| metric | value |
|---|---|
| setSize | 19 |
| pMANOVA | 0.281 |
| p.adjustMANOVA | 0.416 |
| s.dist | 0.232 |
| s.diab | 0.206 |
| s.PMX | -0.107 |
| p.diab | 0.12 |
| p.PMX | 0.42 |
| Gene | diab | PMX |
|---|---|---|
| Plcg1 | 15140 | -14853 |
| Sphk1 | 14600 | -15084 |
| Hras | 12615 | -11955 |
| Pdpk1 | 11828 | -12301 |
| Nras | 11707 | -12390 |
| Itpr1 | 10796 | -11700 |
| Kras | 8243 | -12396 |
| Prkcd | 11350 | -8872 |
| Ahcyl1 | 6832 | -14545 |
| Calm1 | 152 | -11443 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ahcyl1 | 6832 | -14545 |
| Calm1 | 152 | -11443 |
| Hras | 12615 | -11955 |
| Itpr1 | 10796 | -11700 |
| Itpr2 | 13551 | 7710 |
| Itpr3 | 11003 | 2102 |
| Kdr | -12645 | 12884 |
| Kras | 8243 | -12396 |
| Nras | 11707 | -12390 |
| Pdpk1 | 11828 | -12301 |
| Plcg1 | 15140 | -14853 |
| Prkca | -11577 | 11021 |
| Prkcb | -7742 | 7077 |
| Prkcd | 11350 | -8872 |
| Prkcz | -5521 | 12776 |
| Rasa1 | -6341 | 6192 |
| Sphk1 | 14600 | -15084 |
| Src | 8646 | 4243 |
| Vegfa | -12713 | 12720 |
TP53-Regulates-Transcription-of-Genes-Involved-in-G1-Cell-Cycle-Arrest
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.367 |
| p.adjustMANOVA | 0.527 |
| s.dist | 0.244 |
| s.diab | 0.219 |
| s.PMX | -0.107 |
| p.diab | 0.171 |
| p.PMX | 0.502 |
| Gene | diab | PMX |
|---|---|---|
| E2f1 | 14773 | -13127 |
| Cdkn1a | 15394 | -12557 |
| Cdk2 | 12902 | -12285 |
| Zfp385a | 15036 | -8764 |
| Ccne1 | 8507 | -10924 |
| Ccna2 | 12043 | -6678 |
| Ccne2 | 4837 | -11061 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Arid3a | -9238 | 8570 |
| Ccna2 | 12043 | -6678 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdk2 | 12902 | -12285 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| E2f1 | 14773 | -13127 |
| E2f7 | -6064 | 9808 |
| E2f8 | 3208 | 5434 |
| Pcbp4 | -10989 | 12360 |
| Trp53 | -7681 | 5460 |
| Zfp385a | 15036 | -8764 |
NRIF-signals-cell-death-from-the-nucleus
| metric | value |
|---|---|
| setSize | 15 |
| pMANOVA | 0.466 |
| p.adjustMANOVA | 0.65 |
| s.dist | 0.221 |
| s.diab | 0.122 |
| s.PMX | -0.184 |
| p.diab | 0.413 |
| p.PMX | 0.217 |
| Gene | diab | PMX |
|---|---|---|
| Rps27a | 13894 | -14715 |
| Traf6 | 13741 | -14203 |
| Aph1b | 13941 | -13577 |
| Ncstn | 14410 | -12169 |
| Ngfr | 10298 | -6900 |
| Psen2 | 7176 | -5828 |
| Itgb3bp | 4897 | -8304 |
| Uba52 | 4596 | -6796 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Aph1a | -620 | 4686 |
| Aph1b | 13941 | -13577 |
| Itgb3bp | 4897 | -8304 |
| Mapk8 | 86 | 2880 |
| Ncstn | 14410 | -12169 |
| Ngf | -6631 | 2748 |
| Ngfr | 10298 | -6900 |
| Psen1 | -11531 | 9651 |
| Psen2 | 7176 | -5828 |
| Psenen | -7498 | 6057 |
| Rps27a | 13894 | -14715 |
| Sqstm1 | -7943 | 9582 |
| Traf6 | 13741 | -14203 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
Cell-death-signalling-via-NRAGE,-NRIF-and-NADE
| metric | value |
|---|---|
| setSize | 73 |
| pMANOVA | 0.541 |
| p.adjustMANOVA | 0.732 |
| s.dist | 0.0496 |
| s.diab | 0.049 |
| s.PMX | 0.00785 |
| p.diab | 0.469 |
| p.PMX | 0.908 |
| Gene | diab | PMX |
|---|---|---|
| Arhgef17 | 9033 | 10831 |
| Arhgef18 | 12070 | 6649 |
| Arhgef6 | 10050 | 5932 |
| Arhgef2 | 5161 | 9462 |
| Abr | 5382 | 8593 |
| Mcf2l | 10616 | 1746 |
| Mcf2 | 6383 | 2501 |
| Mapk8 | 86 | 2880 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Aatf | 9765 | -12186 |
| Abr | 5382 | 8593 |
| Akap13 | 9135 | -13489 |
| Aph1a | -620 | 4686 |
| Aph1b | 13941 | -13577 |
| Arhgef1 | -4280 | 7936 |
| Arhgef10 | -7339 | 9915 |
| Arhgef10l | -12170 | 12996 |
| Arhgef11 | 9956 | -369 |
| Arhgef12 | -12030 | 10200 |
| Arhgef15 | -12052 | 12723 |
| Arhgef16 | -1056 | 9094 |
| Arhgef17 | 9033 | 10831 |
| Arhgef18 | 12070 | 6649 |
| Arhgef19 | -10659 | 11682 |
| Arhgef2 | 5161 | 9462 |
| Arhgef26 | 12067 | -13084 |
| Arhgef3 | 14506 | -14694 |
| Arhgef33 | 14828 | -14427 |
| Arhgef37 | 14978 | -14679 |
| Arhgef38 | 13842 | -9440 |
| Arhgef39 | -12435 | 12532 |
| Arhgef4 | 15266 | -12127 |
| Arhgef40 | -9136 | 6457 |
| Arhgef5 | 12939 | -13338 |
| Arhgef6 | 10050 | 5932 |
| Arhgef7 | 12872 | -10663 |
| Arhgef9 | 14955 | -14756 |
| Bad | -4775 | 1095 |
| Bcl2l11 | 10641 | -10810 |
| Casp2 | 8278 | -11205 |
| Casp3 | 13749 | -9807 |
| Ect2 | -1535 | -11756 |
| Fgd1 | -3945 | 4745 |
| Fgd2 | -10217 | 12011 |
| Fgd3 | -8287 | -12454 |
| Fgd4 | -1468 | 11977 |
| Gna13 | 5728 | -8712 |
| Itgb3bp | 4897 | -8304 |
| Itsn1 | -6360 | 7586 |
| Kalrn | 13678 | -5190 |
| Maged1 | -11852 | 11971 |
| Mapk8 | 86 | 2880 |
| Mcf2 | 6383 | 2501 |
| Mcf2l | 10616 | 1746 |
| Ncstn | 14410 | -12169 |
| Net1 | 14636 | -15123 |
| Ngef | -11571 | -8755 |
| Ngf | -6631 | 2748 |
| Ngfr | 10298 | -6900 |
| Obscn | -6032 | 7137 |
| Plekhg2 | -10885 | 11872 |
| Plekhg5 | -1787 | 80 |
| Prex1 | -8529 | 12218 |
| Psen1 | -11531 | 9651 |
| Psen2 | 7176 | -5828 |
| Psenen | -7498 | 6057 |
| Rac1 | -4047 | 262 |
| Rasgrf2 | 9870 | -9198 |
| Rps27a | 13894 | -14715 |
| Sos1 | -11977 | 9665 |
| Sos2 | -5483 | 3046 |
| Sqstm1 | -7943 | 9582 |
| Tiam1 | 13330 | -11554 |
| Tiam2 | -6226 | 500 |
| Traf6 | 13741 | -14203 |
| Trio | -9497 | 12173 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
| Vav1 | -9886 | 7973 |
| Vav2 | -4852 | 12450 |
| Vav3 | 14614 | -14980 |
| Ywhae | 2275 | -8018 |
FOXO-mediated-transcription-of-cell-death-genes
| metric | value |
|---|---|
| setSize | 15 |
| pMANOVA | 0.717 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.151 |
| s.diab | -0.0907 |
| s.PMX | 0.121 |
| p.diab | 0.543 |
| p.PMX | 0.417 |
| Gene | diab | PMX |
|---|---|---|
| Nfya | -12328 | 12716 |
| Bcl6 | -11275 | 12055 |
| Pink1 | -11162 | 11930 |
| Ep300 | -10091 | 9600 |
| Nfyb | -7061 | 7045 |
| Stk11 | -4042 | 10593 |
| Fasl | -3718 | 6336 |
| Nfyc | -3343 | 5943 |
| Foxo4 | -4785 | 2785 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Bcl2l11 | 10641 | -10810 |
| Bcl6 | -11275 | 12055 |
| Cited2 | 13876 | -12832 |
| Crebbp | 7115 | -7498 |
| Ddit3 | 13910 | -13026 |
| Ep300 | -10091 | 9600 |
| Fasl | -3718 | 6336 |
| Foxo1 | 8079 | -10792 |
| Foxo3 | 14625 | -14429 |
| Foxo4 | -4785 | 2785 |
| Nfya | -12328 | 12716 |
| Nfyb | -7061 | 7045 |
| Nfyc | -3343 | 5943 |
| Pink1 | -11162 | 11930 |
| Stk11 | -4042 | 10593 |
Oncogene-Induced-Senescence
| metric | value |
|---|---|
| setSize | 31 |
| pMANOVA | 0.736 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.0504 |
| s.diab | -0.0148 |
| s.PMX | -0.0481 |
| p.diab | 0.886 |
| p.PMX | 0.643 |
| Gene | diab | PMX |
|---|---|---|
| Cdk6 | -8022 | -8784 |
| Mdm4 | -4386 | -13416 |
| Id1 | -5552 | -9376 |
| Erf | -4112 | -11941 |
| Ubb | -3411 | -7959 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ago1 | 13694 | -4416 |
| Ago3 | -10688 | 9354 |
| Ago4 | 4723 | 6013 |
| Cdk4 | 7497 | 6438 |
| Cdk6 | -8022 | -8784 |
| Cdkn2b | 14383 | -14293 |
| Cdkn2c | -1158 | 9132 |
| Cdkn2d | 5293 | 2129 |
| E2f1 | 14773 | -13127 |
| E2f2 | -10922 | 8773 |
| E2f3 | 9873 | 3869 |
| Erf | -4112 | -11941 |
| Ets1 | -12235 | 12571 |
| Ets2 | -11047 | 10868 |
| Id1 | -5552 | -9376 |
| Mapk1 | 6867 | -10406 |
| Mapk3 | 10588 | -6813 |
| Mdm2 | 15095 | -7329 |
| Mdm4 | -4386 | -13416 |
| Mov10 | -9876 | 4432 |
| Rb1 | 15102 | -13818 |
| Rps27a | 13894 | -14715 |
| Sp1 | -10774 | 4387 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Tnrc6a | 8288 | -10563 |
| Tnrc6b | -8828 | 9395 |
| Tnrc6c | -6877 | 11145 |
| Trp53 | -7681 | 5460 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
Formation-of-Senescence-Associated-Heterochromatin-Foci-(SAHF)
| metric | value |
|---|---|
| setSize | 11 |
| pMANOVA | 0.747 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.152 |
| s.diab | -0.0756 |
| s.PMX | 0.132 |
| p.diab | 0.664 |
| p.PMX | 0.45 |
| Gene | diab | PMX |
|---|---|---|
| Ubn1 | -10645 | 11079 |
| Lmnb1 | -9916 | 8126 |
| Ep400 | -6397 | 9291 |
| Trp53 | -7681 | 5460 |
| Cabin1 | -3241 | 8514 |
| Hira | -2684 | 4510 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Asf1a | -6271 | -233 |
| Cabin1 | -3241 | 8514 |
| Cdkn1a | 15394 | -12557 |
| Ep400 | -6397 | 9291 |
| Hira | -2684 | 4510 |
| Hmga1 | 14417 | -11978 |
| Hmga2 | 4574 | 275 |
| Lmnb1 | -9916 | 8126 |
| Rb1 | 15102 | -13818 |
| Trp53 | -7681 | 5460 |
| Ubn1 | -10645 | 11079 |
DNA-Damage/Telomere-Stress-Induced-Senescence
| metric | value |
|---|---|
| setSize | 28 |
| pMANOVA | 0.774 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.0506 |
| s.diab | 0.00999 |
| s.PMX | 0.0496 |
| p.diab | 0.927 |
| p.PMX | 0.649 |
| Gene | diab | PMX |
|---|---|---|
| Atm | 11462 | 2585 |
| Kat5 | 4420 | 6683 |
| Hmga2 | 4574 | 275 |
| Cdkn1b | 4380 | 258 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Acd | -4896 | 9107 |
| Asf1a | -6271 | -233 |
| Atm | 11462 | 2585 |
| Cabin1 | -3241 | 8514 |
| Ccna2 | 12043 | -6678 |
| Ccne1 | 8507 | -10924 |
| Ccne2 | 4837 | -11061 |
| Cdk2 | 12902 | -12285 |
| Cdkn1a | 15394 | -12557 |
| Cdkn1b | 4380 | 258 |
| Ep400 | -6397 | 9291 |
| H2afx | -3852 | 6424 |
| Hira | -2684 | 4510 |
| Hmga1 | 14417 | -11978 |
| Hmga2 | 4574 | 275 |
| Kat5 | 4420 | 6683 |
| Lmnb1 | -9916 | 8126 |
| Mre11a | -5960 | 7726 |
| Nbn | -7224 | -4610 |
| Pot1a | -4539 | 2798 |
| Rad50 | 9654 | -3235 |
| Rb1 | 15102 | -13818 |
| Terf1 | -3395 | -5560 |
| Terf2 | -15 | -5815 |
| Terf2ip | -6777 | 9210 |
| Tinf2 | 6319 | -3531 |
| Trp53 | -7681 | 5460 |
| Ubn1 | -10645 | 11079 |
Oxidative-Stress-Induced-Senescence
| metric | value |
|---|---|
| setSize | 62 |
| pMANOVA | 0.786 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.054 |
| s.diab | -0.0489 |
| s.PMX | 0.0229 |
| p.diab | 0.506 |
| p.PMX | 0.755 |
| Gene | diab | PMX |
|---|---|---|
| Rbbp4 | -12462 | 12126 |
| Cbx4 | -12196 | 11468 |
| Mapk11 | -11176 | 11985 |
| Cbx8 | -11721 | 11385 |
| Phc1 | -10307 | 10457 |
| Ago3 | -10688 | 9354 |
| E2f2 | -10922 | 8773 |
| Map2k3 | -11214 | 8360 |
| Tnrc6b | -8828 | 9395 |
| Cbx6 | -6489 | 12600 |
| Tnrc6c | -6877 | 11145 |
| Eed | -9201 | 7028 |
| Cbx2 | -6995 | 8685 |
| Bmi1 | -6546 | 9252 |
| Tfdp1 | -7152 | 7854 |
| Suz12 | -6254 | 8020 |
| Mov10 | -9876 | 4432 |
| Trp53 | -7681 | 5460 |
| Mink1 | -4422 | 8509 |
| H2afx | -3852 | 6424 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Ago1 | 13694 | -4416 |
| Ago3 | -10688 | 9354 |
| Ago4 | 4723 | 6013 |
| Bmi1 | -6546 | 9252 |
| Cbx2 | -6995 | 8685 |
| Cbx4 | -12196 | 11468 |
| Cbx6 | -6489 | 12600 |
| Cbx8 | -11721 | 11385 |
| Cdk4 | 7497 | 6438 |
| Cdk6 | -8022 | -8784 |
| Cdkn2b | 14383 | -14293 |
| Cdkn2c | -1158 | 9132 |
| Cdkn2d | 5293 | 2129 |
| E2f1 | 14773 | -13127 |
| E2f2 | -10922 | 8773 |
| E2f3 | 9873 | 3869 |
| Eed | -9201 | 7028 |
| Ezh2 | 13058 | -14025 |
| Fos | 5077 | 22 |
| H2afx | -3852 | 6424 |
| Jun | 9574 | -13518 |
| Kdm6b | -3039 | -7197 |
| Map2k3 | -11214 | 8360 |
| Map2k4 | 9926 | -8899 |
| Map2k6 | 8630 | -9645 |
| Map2k7 | 12018 | -8043 |
| Map3k5 | 10364 | -13897 |
| Map4k4 | -6607 | 13 |
| Mapk1 | 6867 | -10406 |
| Mapk10 | 6586 | -10216 |
| Mapk11 | -11176 | 11985 |
| Mapk14 | -12047 | 34 |
| Mapk3 | 10588 | -6813 |
| Mapk8 | 86 | 2880 |
| Mapk9 | 12784 | -5874 |
| Mapkapk2 | 14192 | -11215 |
| Mapkapk3 | 8522 | 6234 |
| Mapkapk5 | 41 | 3388 |
| Mdm2 | 15095 | -7329 |
| Mdm4 | -4386 | -13416 |
| Mink1 | -4422 | 8509 |
| Mov10 | -9876 | 4432 |
| Phc1 | -10307 | 10457 |
| Phc2 | 9767 | -7629 |
| Phc3 | -8753 | -8471 |
| Rbbp4 | -12462 | 12126 |
| Rbbp7 | 225 | -7926 |
| Ring1 | -7720 | 3003 |
| Rnf2 | 5830 | -10843 |
| Rps27a | 13894 | -14715 |
| Scmh1 | 7958 | 5549 |
| Suz12 | -6254 | 8020 |
| Tfdp1 | -7152 | 7854 |
| Tfdp2 | 12095 | -12073 |
| Tnik | -1447 | 2760 |
| Tnrc6a | 8288 | -10563 |
| Tnrc6b | -8828 | 9395 |
| Tnrc6c | -6877 | 11145 |
| Trp53 | -7681 | 5460 |
| Txn1 | -6434 | -12085 |
| Uba52 | 4596 | -6796 |
| Ubb | -3411 | -7959 |
Diseases-of-programmed-cell-death
| metric | value |
|---|---|
| setSize | 42 |
| pMANOVA | 0.8 |
| p.adjustMANOVA | 0.92 |
| s.dist | 0.0436 |
| s.diab | -0.0436 |
| s.PMX | 2e-04 |
| p.diab | 0.625 |
| p.PMX | 0.998 |
| Gene | diab | PMX |
|---|---|---|
| Dnmt3a | -12219 | 12965 |
| Rbbp4 | -12462 | 12126 |
| Dnmt1 | -9863 | 10248 |
| Fadd | -9345 | 10811 |
| Prim1 | -8624 | 10425 |
| Tradd | -7820 | 11319 |
| App | -8366 | 10137 |
| Prdx1 | -11307 | 7421 |
| Lmnb1 | -9916 | 8126 |
| Eed | -9201 | 7028 |
| C1qbp | -5400 | 10357 |
| Prim2 | -9097 | 5742 |
| Pola1 | -8880 | 5777 |
| Suz12 | -6254 | 8020 |
| Trp53 | -7681 | 5460 |
| Capns2 | -3872 | 8278 |
| H2afx | -3852 | 6424 |
| Fasl | -3718 | 6336 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| App | -8366 | 10137 |
| Bcl2l11 | 10641 | -10810 |
| C1qbp | -5400 | 10357 |
| Capn1 | 15297 | -14590 |
| Capn2 | 14380 | -14044 |
| Capns1 | 10893 | -14245 |
| Capns2 | -3872 | 8278 |
| Casp8 | -8679 | -12376 |
| Cast | 13527 | -11562 |
| Cdc25a | 3462 | -12613 |
| Cdc25b | 8473 | 6982 |
| Cdc25c | 9859 | -6321 |
| Cdk5 | 9839 | 2913 |
| Cdk5r1 | -4054 | -4627 |
| Dnmt1 | -9863 | 10248 |
| Dnmt3a | -12219 | 12965 |
| Dnmt3b | 3290 | 280 |
| Eed | -9201 | 7028 |
| Ezh2 | 13058 | -14025 |
| Fadd | -9345 | 10811 |
| Fasl | -3718 | 6336 |
| Foxo3 | 14625 | -14429 |
| Golga2 | 14538 | -13457 |
| H2afx | -3852 | 6424 |
| Jun | 9574 | -13518 |
| Lmna | 5606 | 3857 |
| Lmnb1 | -9916 | 8126 |
| Pola1 | -8880 | 5777 |
| Pola2 | 8004 | -5681 |
| Prdx1 | -11307 | 7421 |
| Prdx2 | 14368 | -13945 |
| Prim1 | -8624 | 10425 |
| Prim2 | -9097 | 5742 |
| Rbbp4 | -12462 | 12126 |
| Rbbp7 | 225 | -7926 |
| Ripk1 | -961 | -5249 |
| Sod2 | 5661 | -10164 |
| Suz12 | -6254 | 8020 |
| Tradd | -7820 | 11319 |
| Traf2 | 3101 | -8023 |
| Trp53 | -7681 | 5460 |
| Ywhae | 2275 | -8018 |
TP53-Regulates-Transcription-of-Cell-Death-Genes
| metric | value |
|---|---|
| setSize | 37 |
| pMANOVA | 0.84 |
| p.adjustMANOVA | 0.943 |
| s.dist | 0.0373 |
| s.diab | 0.0055 |
| s.PMX | 0.0369 |
| p.diab | 0.954 |
| p.PMX | 0.698 |
| Gene | diab | PMX |
|---|---|---|
| Tnfrsf10b | 14466 | 8404 |
| Bax | 11957 | 8555 |
| Bcl2l14 | 14259 | 2653 |
| Atm | 11462 | 2585 |
| Trp73 | 5178 | 5617 |
| Ppp1r13b | 12643 | 273 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Aifm2 | 11725 | -3780 |
| Apaf1 | -3549 | 11897 |
| Atm | 11462 | 2585 |
| Bax | 11957 | 8555 |
| Bcl2l14 | 14259 | 2653 |
| Bcl6 | -11275 | 12055 |
| Bid | -5300 | 6403 |
| Birc5 | 12522 | -11275 |
| Bnip3l | -4880 | -13318 |
| Casp1 | -11186 | 11334 |
| Casp2 | 8278 | -11205 |
| Casp6 | -1176 | 5396 |
| Chm | -2990 | -10097 |
| Cradd | -9168 | 8664 |
| Crebbp | 7115 | -7498 |
| Fas | 13656 | -13454 |
| Igfbp3 | -12060 | 12876 |
| Ndrg1 | 12041 | -13368 |
| Nlrc4 | -12130 | 5387 |
| Perp | -11532 | 5317 |
| Pidd1 | -1135 | -8779 |
| Pmaip1 | 15067 | -12274 |
| Ppp1r13b | 12643 | 273 |
| Prelid1 | -4414 | 1639 |
| Rabggta | -12513 | 11451 |
| Rabggtb | 12899 | -14355 |
| Slmo1 | 5847 | -3763 |
| Steap3 | -11527 | 9153 |
| Tmem219 | -4797 | -6817 |
| Tnfrsf10b | 14466 | 8404 |
| Triap1 | -7647 | 2924 |
| Trp53 | -7681 | 5460 |
| Trp53bp2 | 12692 | -12481 |
| Trp53inp1 | 15269 | -14119 |
| Trp63 | -5205 | -10040 |
| Trp73 | 5178 | 5617 |
| Zfp420 | -5708 | 8399 |
TP53-regulates-transcription-of-several-additional-cell-death-genes-whose-specific-roles-in-p53-dependent-apoptosis-remain-uncertain
| metric | value |
|---|---|
| setSize | 13 |
| pMANOVA | 0.864 |
| p.adjustMANOVA | 0.946 |
| s.dist | 0.112 |
| s.diab | 0.0768 |
| s.PMX | -0.0817 |
| p.diab | 0.632 |
| p.PMX | 0.61 |
| Gene | diab | PMX |
|---|---|---|
| Rabggtb | 12899 | -14355 |
| Ndrg1 | 12041 | -13368 |
| Trp53bp2 | 12692 | -12481 |
| Birc5 | 12522 | -11275 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Bcl2l14 | 14259 | 2653 |
| Bcl6 | -11275 | 12055 |
| Birc5 | 12522 | -11275 |
| Chm | -2990 | -10097 |
| Ndrg1 | 12041 | -13368 |
| Perp | -11532 | 5317 |
| Ppp1r13b | 12643 | 273 |
| Rabggta | -12513 | 11451 |
| Rabggtb | 12899 | -14355 |
| Trp53 | -7681 | 5460 |
| Trp53bp2 | 12692 | -12481 |
| Trp63 | -5205 | -10040 |
| Trp73 | 5178 | 5617 |
Cell-recruitment-(pro-inflammatory-response)
| metric | value |
|---|---|
| setSize | 24 |
| pMANOVA | 0.9 |
| p.adjustMANOVA | 0.954 |
| s.dist | 0.0693 |
| s.diab | -0.0445 |
| s.PMX | 0.053 |
| p.diab | 0.706 |
| p.PMX | 0.653 |
| Gene | diab | PMX |
|---|---|---|
| Hsp90ab1 | -12580 | 11764 |
| Casp1 | -11186 | 11334 |
| Pstpip1 | -10529 | 11013 |
| Hmox1 | -10213 | 8284 |
| Mefv | -7814 | 9211 |
| Il1b | -10853 | 6461 |
| Nlrp3 | -8573 | 7411 |
| Gsdmd | -5959 | 7991 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| C3 | 15250.0 | -14907.0 |
| C3ar1 | -4139.0 | -6179.0 |
| Casp1 | -11186.0 | 11334.0 |
| Entpd1 | 15235.0 | -14142.0 |
| Entpd5 | -3477.0 | -2420.0 |
| Gsdmd | -5959.0 | 7991.0 |
| Hmox1 | -10213.0 | 8284.0 |
| Hsp90ab1 | -12580.0 | 11764.0 |
| Il18 | 9046.0 | 6574.0 |
| Il1a | 876.5 | -1222.5 |
| Il1b | -10853.0 | 6461.0 |
| Mefv | -7814.0 | 9211.0 |
| Nfkb1 | 234.0 | 10216.0 |
| Nfkb2 | 8531.0 | 1475.0 |
| Nlrp3 | -8573.0 | 7411.0 |
| Nt5e | -9052.0 | -9847.0 |
| P2rx4 | 13993.0 | -11444.0 |
| P2rx7 | 10761.0 | -3230.0 |
| Pstpip1 | -10529.0 | 11013.0 |
| Pycard | 10546.0 | 8949.0 |
| Rela | 7998.0 | -10978.0 |
| Sugt1 | 9604.0 | -6859.0 |
| Txn1 | -6434.0 | -12085.0 |
| Txnip | 15044.0 | -15001.0 |
TP53-regulates-transcription-of-additional-cell-cycle-genes-whose-exact-role-in-the-p53-pathway-remain-uncertain
| metric | value |
|---|---|
| setSize | 19 |
| pMANOVA | 0.933 |
| p.adjustMANOVA | 0.954 |
| s.dist | 0.0621 |
| s.diab | 0.0488 |
| s.PMX | -0.0384 |
| p.diab | 0.713 |
| p.PMX | 0.772 |
| Gene | diab | PMX |
|---|---|---|
| Btg2 | 15122 | -14014 |
| Rgcc | 14711 | -13598 |
| Plk3 | 14013 | -14168 |
| Plagl1 | 14219 | -8257 |
| Cnot6l | 6231 | -12283 |
| Cdc25c | 9859 | -6321 |
| Tnks1bp1 | 4119 | -14130 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Btg2 | 15122 | -14014 |
| Cdc25c | 9859 | -6321 |
| Cenpj | -11728 | 6522 |
| Cnot1 | 2862 | 4781 |
| Cnot10 | 8561 | 1690 |
| Cnot11 | -131 | 2908 |
| Cnot2 | -6965 | 6675 |
| Cnot3 | -8690 | 6241 |
| Cnot4 | -7023 | 1964 |
| Cnot6 | -4378 | 2900 |
| Cnot6l | 6231 | -12283 |
| Cnot7 | -8230 | -5989 |
| Cnot8 | -10527 | 7261 |
| Plagl1 | 14219 | -8257 |
| Plk2 | 13531 | 11848 |
| Plk3 | 14013 | -14168 |
| Rgcc | 14711 | -13598 |
| Tnks1bp1 | 4119 | -14130 |
| Trp53 | -7681 | 5460 |
EGR2-and-SOX10-mediated-initiation-of-Schwann-cell-myelination
| metric | value |
|---|---|
| setSize | 27 |
| pMANOVA | 0.934 |
| p.adjustMANOVA | 0.954 |
| s.dist | 0.0446 |
| s.diab | -0.0398 |
| s.PMX | 0.0202 |
| p.diab | 0.72 |
| p.PMX | 0.856 |
| Gene | diab | PMX |
|---|---|---|
| Nab2 | -12557 | 12629 |
| Lama2 | -12274 | 12567 |
| Lamb1 | -8857 | 11401 |
| Hdac2 | -9129 | 7139 |
| Egr2 | -8943 | 6151 |
| Yap1 | -7550 | 6222 |
| Smarca4 | -4424 | 10551 |
| Nab1 | -9570 | 4452 |
| Srebf2 | -4237 | 9342 |
| Pmp22 | -3954 | 6790 |
| Tead1 | -3955 | 2810 |
| Sox10 | -1524 | 3549 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Adgrg6 | 12923 | -14467 |
| Adgrv1 | 10549 | -5789 |
| Cyp51 | 11509 | -15089 |
| Dag1 | 14086 | 305 |
| Drp2 | 2856 | -2916 |
| Egr2 | -8943 | 6151 |
| Gjb1 | -1862 | -13995 |
| Hdac2 | -9129 | 7139 |
| Hmgcr | -11695 | -12651 |
| Lama2 | -12274 | 12567 |
| Lamb1 | -8857 | 11401 |
| Lamc1 | 13297 | -9372 |
| Mag | 6844 | -8991 |
| Mbp | 14194 | 3469 |
| Mpz | 11473 | -447 |
| Nab1 | -9570 | 4452 |
| Nab2 | -12557 | 12629 |
| Pmp22 | -3954 | 6790 |
| Pou3f1 | -1704 | -5253 |
| Prx | 5888 | -3055 |
| Smarca4 | -4424 | 10551 |
| Sox10 | -1524 | 3549 |
| Srebf2 | -4237 | 9342 |
| Tead1 | -3955 | 2810 |
| Utrn | 13490 | -12047 |
| Wwtr1 | 5283 | -14386 |
| Yap1 | -7550 | 6222 |
Cellular-Senescence
| metric | value |
|---|---|
| setSize | 124 |
| pMANOVA | 0.954 |
| p.adjustMANOVA | 0.954 |
| s.dist | 0.00952 |
| s.diab | -0.00377 |
| s.PMX | -0.00874 |
| p.diab | 0.942 |
| p.PMX | 0.866 |
| Gene | diab | PMX |
|---|---|---|
| Txn1 | -6434 | -12085 |
| Phc3 | -8753 | -8471 |
| Cdk6 | -8022 | -8784 |
| Igfbp7 | -6756 | -9670 |
| Mdm4 | -4386 | -13416 |
| Id1 | -5552 | -9376 |
| Erf | -4112 | -11941 |
| Ehmt1 | -4418 | -10516 |
| Cdc27 | -6730 | -6274 |
| Nbn | -7224 | -4610 |
| Ubb | -3411 | -7959 |
| Anapc15 | -2513 | -9553 |
| Kdm6b | -3039 | -7197 |
| Terf1 | -3395 | -5560 |
| Anapc11 | -4767 | -2276 |
| Asf1a | -6271 | -233 |
| Anapc10 | -40 | -7692 |
| Terf2 | -15 | -5815 |
Click HERE to show all gene set members
| diab | PMX | |
|---|---|---|
| Acd | -4896.0 | 9107.0 |
| Ago1 | 13694.0 | -4416.0 |
| Ago3 | -10688.0 | 9354.0 |
| Ago4 | 4723.0 | 6013.0 |
| Anapc1 | -11278.0 | 10450.0 |
| Anapc10 | -40.0 | -7692.0 |
| Anapc11 | -4767.0 | -2276.0 |
| Anapc15 | -2513.0 | -9553.0 |
| Anapc16 | 13128.0 | -13447.0 |
| Anapc2 | -3217.0 | 9388.0 |
| Anapc4 | 14276.0 | -12248.0 |
| Anapc5 | 14536.0 | -12088.0 |
| Anapc7 | 10824.0 | -6183.0 |
| Asf1a | -6271.0 | -233.0 |
| Atm | 11462.0 | 2585.0 |
| Bmi1 | -6546.0 | 9252.0 |
| Cabin1 | -3241.0 | 8514.0 |
| Cbx2 | -6995.0 | 8685.0 |
| Cbx4 | -12196.0 | 11468.0 |
| Cbx6 | -6489.0 | 12600.0 |
| Cbx8 | -11721.0 | 11385.0 |
| Ccna2 | 12043.0 | -6678.0 |
| Ccne1 | 8507.0 | -10924.0 |
| Ccne2 | 4837.0 | -11061.0 |
| Cdc16 | 10625.0 | -286.0 |
| Cdc23 | 180.0 | 8382.0 |
| Cdc26 | 8205.0 | -5823.0 |
| Cdc27 | -6730.0 | -6274.0 |
| Cdk2 | 12902.0 | -12285.0 |
| Cdk4 | 7497.0 | 6438.0 |
| Cdk6 | -8022.0 | -8784.0 |
| Cdkn1a | 15394.0 | -12557.0 |
| Cdkn1b | 4380.0 | 258.0 |
| Cdkn2b | 14383.0 | -14293.0 |
| Cdkn2c | -1158.0 | 9132.0 |
| Cdkn2d | 5293.0 | 2129.0 |
| Cebpb | 15167.0 | -15133.0 |
| E2f1 | 14773.0 | -13127.0 |
| E2f2 | -10922.0 | 8773.0 |
| E2f3 | 9873.0 | 3869.0 |
| Eed | -9201.0 | 7028.0 |
| Ehmt1 | -4418.0 | -10516.0 |
| Ehmt2 | 4354.0 | 10437.0 |
| Ep400 | -6397.0 | 9291.0 |
| Erf | -4112.0 | -11941.0 |
| Ets1 | -12235.0 | 12571.0 |
| Ets2 | -11047.0 | 10868.0 |
| Ezh2 | 13058.0 | -14025.0 |
| Fos | 5077.0 | 22.0 |
| Fzr1 | -2715.0 | 9851.0 |
| H2afx | -3852.0 | 6424.0 |
| Hira | -2684.0 | 4510.0 |
| Hmga1 | 14417.0 | -11978.0 |
| Hmga2 | 4574.0 | 275.0 |
| Id1 | -5552.0 | -9376.0 |
| Igfbp7 | -6756.0 | -9670.0 |
| Il1a | 876.5 | -1222.5 |
| Il6 | -2929.0 | 3096.0 |
| Jun | 9574.0 | -13518.0 |
| Kat5 | 4420.0 | 6683.0 |
| Kdm6b | -3039.0 | -7197.0 |
| Lmnb1 | -9916.0 | 8126.0 |
| Map2k3 | -11214.0 | 8360.0 |
| Map2k4 | 9926.0 | -8899.0 |
| Map2k6 | 8630.0 | -9645.0 |
| Map2k7 | 12018.0 | -8043.0 |
| Map3k5 | 10364.0 | -13897.0 |
| Map4k4 | -6607.0 | 13.0 |
| Mapk1 | 6867.0 | -10406.0 |
| Mapk10 | 6586.0 | -10216.0 |
| Mapk11 | -11176.0 | 11985.0 |
| Mapk14 | -12047.0 | 34.0 |
| Mapk3 | 10588.0 | -6813.0 |
| Mapk7 | -1452.0 | 6080.0 |
| Mapk8 | 86.0 | 2880.0 |
| Mapk9 | 12784.0 | -5874.0 |
| Mapkapk2 | 14192.0 | -11215.0 |
| Mapkapk3 | 8522.0 | 6234.0 |
| Mapkapk5 | 41.0 | 3388.0 |
| Mdm2 | 15095.0 | -7329.0 |
| Mdm4 | -4386.0 | -13416.0 |
| Mink1 | -4422.0 | 8509.0 |
| Mov10 | -9876.0 | 4432.0 |
| Mre11a | -5960.0 | 7726.0 |
| Nbn | -7224.0 | -4610.0 |
| Nfkb1 | 234.0 | 10216.0 |
| Phc1 | -10307.0 | 10457.0 |
| Phc2 | 9767.0 | -7629.0 |
| Phc3 | -8753.0 | -8471.0 |
| Pot1a | -4539.0 | 2798.0 |
| Rad50 | 9654.0 | -3235.0 |
| Rb1 | 15102.0 | -13818.0 |
| Rbbp4 | -12462.0 | 12126.0 |
| Rbbp7 | 225.0 | -7926.0 |
| Rela | 7998.0 | -10978.0 |
| Ring1 | -7720.0 | 3003.0 |
| Rnf2 | 5830.0 | -10843.0 |
| Rps27a | 13894.0 | -14715.0 |
| Rps6ka1 | 13571.0 | 8925.0 |
| Rps6ka2 | 14482.0 | -10261.0 |
| Rps6ka3 | -7830.0 | 5782.0 |
| Scmh1 | 7958.0 | 5549.0 |
| Sp1 | -10774.0 | 4387.0 |
| Stat3 | 14430.0 | -14454.0 |
| Suz12 | -6254.0 | 8020.0 |
| Terf1 | -3395.0 | -5560.0 |
| Terf2 | -15.0 | -5815.0 |
| Terf2ip | -6777.0 | 9210.0 |
| Tfdp1 | -7152.0 | 7854.0 |
| Tfdp2 | 12095.0 | -12073.0 |
| Tinf2 | 6319.0 | -3531.0 |
| Tnik | -1447.0 | 2760.0 |
| Tnrc6a | 8288.0 | -10563.0 |
| Tnrc6b | -8828.0 | 9395.0 |
| Tnrc6c | -6877.0 | 11145.0 |
| Trp53 | -7681.0 | 5460.0 |
| Txn1 | -6434.0 | -12085.0 |
| Uba52 | 4596.0 | -6796.0 |
| Ubb | -3411.0 | -7959.0 |
| Ube2c | 9861.0 | -8024.0 |
| Ube2d1 | 11721.0 | -13291.0 |
| Ube2e1 | -10811.0 | 7252.0 |
| Ube2s | 9693.0 | -6037.0 |
| Ubn1 | -10645.0 | 11079.0 |
Here is the session info with all the versions of packages used.
sessionInfo()## R version 4.1.1 (2021-08-10)
## Platform: x86_64-pc-linux-gnu (64-bit)
## Running under: Ubuntu 20.04.3 LTS
##
## Matrix products: default
## BLAS: /usr/lib/x86_64-linux-gnu/openblas-pthread/libblas.so.3
## LAPACK: /usr/lib/x86_64-linux-gnu/openblas-pthread/liblapack.so.3
##
## locale:
## [1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
## [3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
## [5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
## [7] LC_PAPER=en_US.UTF-8 LC_NAME=C
## [9] LC_ADDRESS=C LC_TELEPHONE=C
## [11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
##
## attached base packages:
## [1] parallel stats4 stats graphics grDevices utils datasets
## [8] methods base
##
## other attached packages:
## [1] pkgload_1.2.1 GGally_2.1.2
## [3] ggplot2_3.3.5 reshape2_1.4.4
## [5] beeswarm_0.4.0 gplots_3.1.1
## [7] gtools_3.9.2 tibble_3.1.4
## [9] echarts4r_0.4.1 kableExtra_1.3.4
## [11] dplyr_1.0.7 mitch_1.5.1
## [13] DESeq2_1.32.0 SummarizedExperiment_1.22.0
## [15] Biobase_2.52.0 MatrixGenerics_1.4.3
## [17] matrixStats_0.60.1 GenomicRanges_1.44.0
## [19] GenomeInfoDb_1.28.4 IRanges_2.26.0
## [21] S4Vectors_0.30.0 BiocGenerics_0.38.0
##
## loaded via a namespace (and not attached):
## [1] colorspace_2.0-2 ellipsis_0.3.2 rprojroot_2.0.2
## [4] XVector_0.32.0 rstudioapi_0.13 farver_2.1.0
## [7] bit64_4.0.5 AnnotationDbi_1.54.1 fansi_0.5.0
## [10] xml2_1.3.2 splines_4.1.1 cachem_1.0.6
## [13] geneplotter_1.70.0 knitr_1.34 jsonlite_1.7.2
## [16] annotate_1.70.0 png_0.1-7 shiny_1.6.0
## [19] compiler_4.1.1 httr_1.4.2 assertthat_0.2.1
## [22] Matrix_1.3-4 fastmap_1.1.0 later_1.3.0
## [25] htmltools_0.5.2 tools_4.1.1 gtable_0.3.0
## [28] glue_1.4.2 GenomeInfoDbData_1.2.6 Rcpp_1.0.7
## [31] jquerylib_0.1.4 vctrs_0.3.8 Biostrings_2.60.2
## [34] svglite_2.0.0 xfun_0.25 stringr_1.4.0
## [37] testthat_3.0.4 rvest_1.0.1 mime_0.11
## [40] lifecycle_1.0.0 XML_3.99-0.7 zlibbioc_1.38.0
## [43] MASS_7.3-54 scales_1.1.1 promises_1.2.0.1
## [46] RColorBrewer_1.1-2 yaml_2.2.1 memoise_2.0.0
## [49] gridExtra_2.3 sass_0.4.0 reshape_0.8.8
## [52] stringi_1.7.4 RSQLite_2.2.8 highr_0.9
## [55] genefilter_1.74.0 desc_1.3.0 caTools_1.18.2
## [58] BiocParallel_1.26.2 rlang_0.4.11 pkgconfig_2.0.3
## [61] systemfonts_1.0.2 bitops_1.0-7 evaluate_0.14
## [64] lattice_0.20-45 purrr_0.3.4 labeling_0.4.2
## [67] htmlwidgets_1.5.4 bit_4.0.4 tidyselect_1.1.1
## [70] plyr_1.8.6 magrittr_2.0.1 R6_2.5.1
## [73] generics_0.1.0 DelayedArray_0.18.0 DBI_1.1.1
## [76] pillar_1.6.2 withr_2.4.2 survival_3.2-13
## [79] KEGGREST_1.32.0 RCurl_1.98-1.4 crayon_1.4.1
## [82] KernSmooth_2.23-20 utf8_1.2.2 rmarkdown_2.10
## [85] locfit_1.5-9.4 grid_4.1.1 blob_1.2.2
## [88] digest_0.6.27 webshot_0.5.2 xtable_1.8-4
## [91] httpuv_1.6.2 munsell_0.5.0 viridisLite_0.4.0
## [94] bslib_0.3.0END of report